Homo sapiens

117 known processes

IFIT1

interferon-induced protein with tetratricopeptide repeats 1

(Aliases: IFI-56,C56,IFIT-1,ISG56,IFNAI1,IFI-56K,G10P1,GARG-16,IFI56,RNM561)

IFIT1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multi organism intracellular transport GO:1902583 14 1.000
intracellular transport of viral protein in host cell GO:0019060 4 1.000
extracellular transport GO:0006858 4 1.000
intracellular protein transport in other organism involved in symbiotic interaction GO:0051708 4 1.000
negative regulation of defense response to virus by host GO:0050689 4 0.999
regulation by virus of viral protein levels in host cell GO:0046719 4 0.999
viral life cycle GO:0019058 132 0.995
cellular response to dsrna GO:0071359 19 0.994
symbiont intracellular protein transport in host GO:0030581 4 0.992
transport of virus GO:0046794 14 0.992
intracellular transport of virus GO:0075733 14 0.990
multi organism localization GO:1902579 14 0.988
regulation of helicase activity GO:0051095 8 0.985
regulation of defense response to virus GO:0050688 33 0.983
multi organism transport GO:0044766 14 0.982
regulation of defense response to virus by host GO:0050691 22 0.977
response to dsrna GO:0043331 25 0.975
viral genome replication GO:0019079 50 0.974
cellular response to interferon alpha GO:0035457 4 0.973
Mouse
negative regulation of viral genome replication GO:0045071 35 0.970
response to cytokine GO:0034097 232 0.966
regulation of viral process GO:0050792 103 0.934
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.920
interaction with host GO:0051701 42 0.918
response to interferon alpha GO:0035455 11 0.915
Mouse
defense response to virus GO:0051607 71 0.909
negative regulation of viral process GO:0048525 66 0.900
response to biotic stimulus GO:0009607 276 0.900
response to external biotic stimulus GO:0043207 261 0.895
cellular response to type i interferon GO:0071357 12 0.891
interspecies interaction between organisms GO:0044419 156 0.886
response to other organism GO:0051707 261 0.883
negative regulation of defense response to virus GO:0050687 10 0.879
organophosphate biosynthetic process GO:0090407 163 0.862
cellular response to organic cyclic compound GO:0071407 127 0.858
multi organism cellular process GO:0044764 156 0.832
regulation of protein binding GO:0043393 66 0.830
negative regulation of binding GO:0051100 57 0.825
cellular response to exogenous dsrna GO:0071360 5 0.813
negative regulation of multi organism process GO:0043901 92 0.813
cellular response to cytokine stimulus GO:0071345 181 0.802
response to type i interferon GO:0034340 14 0.786
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.764
defense response GO:0006952 315 0.760
response to organic cyclic compound GO:0014070 204 0.750
regulation of multi organism process GO:0043900 157 0.727
positive regulation of viral process GO:0048524 37 0.726
regulation of viral genome replication GO:0045069 48 0.717
negative regulation of cell death GO:0060548 345 0.716
Human
regulation of defense response GO:0031347 154 0.716
intracellular protein transport GO:0006886 270 0.713
negative regulation of programmed cell death GO:0043069 321 0.713
Human
negative regulation of protein binding GO:0032091 35 0.698
positive regulation of rig i signaling pathway GO:1900246 4 0.676
negative regulation of helicase activity GO:0051097 2 0.665
immune response GO:0006955 307 0.634
negative regulation of apoptotic process GO:0043066 316 0.626
Human
response to nitrogen compound GO:1901698 184 0.611
negative regulation of response to external stimulus GO:0032102 83 0.579
chemical homeostasis GO:0048878 306 0.579
response to virus GO:0009615 126 0.565
regulation of binding GO:0051098 111 0.556
negative regulation of response to biotic stimulus GO:0002832 18 0.537
negative regulation of catalytic activity GO:0043086 335 0.531
negative regulation of cell proliferation GO:0008285 228 0.531
Human
response to phenylpropanoid GO:0080184 1 0.521
regulation of response to biotic stimulus GO:0002831 55 0.495
negative regulation of immune system process GO:0002683 136 0.488
positive regulation of cell death GO:0010942 263 0.457
Human
positive regulation of multi organism process GO:0043902 56 0.440
positive regulation of apoptotic process GO:0043065 246 0.438
Human
innate immune response GO:0045087 178 0.412
defense response to other organism GO:0098542 129 0.403
immune effector process GO:0002252 159 0.402
cellular response to nitrogen compound GO:1901699 144 0.313
negative regulation of defense response GO:0031348 47 0.310
negative regulation of hydrolase activity GO:0051346 182 0.306
positive regulation of programmed cell death GO:0043068 249 0.293
Human
negative regulation of immune effector process GO:0002698 38 0.286
viral process GO:0016032 146 0.281
regulation of response to external stimulus GO:0032101 222 0.245
regulation of immune effector process GO:0002697 91 0.215
regulation of mda 5 signaling pathway GO:0039533 4 0.198
nuclear transport GO:0051169 179 0.185
posttranscriptional gene silencing GO:0016441 25 0.176
regulation of rig i signaling pathway GO:0039535 6 0.161
response to exogenous dsrna GO:0043330 10 0.148
posttranscriptional regulation of gene expression GO:0010608 213 0.140
negative regulation of protein metabolic process GO:0051248 391 0.133
glycosylation GO:0070085 71 0.125
positive regulation of viral genome replication GO:0045070 15 0.124
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.115
cellular response to interferon beta GO:0035458 6 0.108
Mouse
immune system development GO:0002520 195 0.078
organonitrogen compound biosynthetic process GO:1901566 200 0.070
regulation of protein transport GO:0051223 213 0.066
positive regulation of intracellular protein transport GO:0090316 76 0.064
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.064
regulation of ribonuclease activity GO:0060700 3 0.062
negative regulation of cellular protein metabolic process GO:0032269 353 0.060
regulation of protein ubiquitination GO:0031396 95 0.051
modification dependent macromolecule catabolic process GO:0043632 212 0.050
organophosphate catabolic process GO:0046434 430 0.049
rig i signaling pathway GO:0039529 7 0.048
hemopoiesis GO:0030097 180 0.048
glucose metabolic process GO:0006006 45 0.043
rna interference GO:0016246 4 0.043
nucleoside diphosphate phosphorylation GO:0006165 12 0.042
nucleoside triphosphate metabolic process GO:0009141 422 0.041
protein targeting GO:0006605 187 0.040
regulation of nucleocytoplasmic transport GO:0046822 98 0.039
glycoprotein biosynthetic process GO:0009101 91 0.039
mda 5 signaling pathway GO:0039530 4 0.038
purine containing compound biosynthetic process GO:0072522 88 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.037
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039532 3 0.036
protein ubiquitination GO:0016567 314 0.034
carbohydrate derivative biosynthetic process GO:1901137 207 0.034
nucleotide catabolic process GO:0009166 408 0.034
protein modification by small protein conjugation GO:0032446 342 0.034
negative regulation of proteolysis GO:0045861 132 0.033
modification dependent protein catabolic process GO:0019941 209 0.033
regulation of gene expression epigenetic GO:0040029 73 0.032
release of cytochrome c from mitochondria GO:0001836 35 0.030
lipid biosynthetic process GO:0008610 177 0.029
negative regulation of transport GO:0051051 176 0.028
single organism carbohydrate metabolic process GO:0044723 193 0.028
t helper 2 cell cytokine production GO:0035745 3 0.028
secretion by cell GO:0032940 226 0.027
cellular macromolecular complex assembly GO:0034622 324 0.027
single organism cellular localization GO:1902580 332 0.027
cardiovascular system development GO:0072358 262 0.026
positive regulation of intracellular transport GO:0032388 104 0.025
positive regulation of proteolysis GO:0045862 142 0.025
lens morphogenesis in camera type eye GO:0002089 2 0.025
positive regulation of transferase activity GO:0051347 227 0.025
isg15 protein conjugation GO:0032020 5 0.025
negative regulation of protein maturation GO:1903318 142 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
mapk cascade GO:0000165 288 0.022
protein export from nucleus GO:0006611 29 0.022
cytoplasmic transport GO:0016482 379 0.022
positive regulation of kinase activity GO:0033674 204 0.022
cellular response to unfolded protein GO:0034620 16 0.022
ion homeostasis GO:0050801 230 0.021
cellular amino acid metabolic process GO:0006520 116 0.021
ribonucleoprotein complex assembly GO:0022618 78 0.021
negative regulation of gene silencing by rna GO:0060967 3 0.021
negative regulation of rig i signaling pathway GO:0039536 2 0.021
positive regulation of homeostatic process GO:0032846 47 0.021
cellular response to molecule of bacterial origin GO:0071219 62 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.020
cellular lipid metabolic process GO:0044255 303 0.020
protein catabolic process GO:0030163 325 0.020
positive regulation of developmental process GO:0051094 314 0.020
rna processing GO:0006396 255 0.019
regulation of protein localization GO:0032880 296 0.019
regulation of actin filament based process GO:0032970 141 0.019
gene silencing by rna GO:0031047 26 0.019
regulation of erythrocyte differentiation GO:0045646 17 0.019
negative regulation of protein ubiquitination GO:0031397 35 0.019
positive regulation of response to external stimulus GO:0032103 88 0.019
regulation of locomotion GO:0040012 329 0.019
intracellular receptor signaling pathway GO:0030522 104 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
negative regulation of protein modification process GO:0031400 200 0.018
carboxylic acid biosynthetic process GO:0046394 97 0.018
nucleoside phosphate biosynthetic process GO:1901293 109 0.018
regulation of cytoskeleton organization GO:0051493 177 0.018
protein localization to organelle GO:0033365 280 0.018
protein maturation GO:0051604 233 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
glycosyl compound catabolic process GO:1901658 413 0.017
protein import GO:0017038 130 0.017
nucleoside phosphate catabolic process GO:1901292 412 0.017
cellular response to oxygen containing compound GO:1901701 276 0.017
single organism nuclear import GO:1902593 104 0.017
wnt signaling pathway GO:0016055 156 0.017
nucleoside catabolic process GO:0009164 408 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
cellular protein catabolic process GO:0044257 261 0.016
regulation of transferase activity GO:0051338 355 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
mrna metabolic process GO:0016071 175 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
protein targeting to nucleus GO:0044744 104 0.016
organic acid biosynthetic process GO:0016053 97 0.015
small molecule biosynthetic process GO:0044283 157 0.015
single organism membrane organization GO:0044802 268 0.015
regulation of t helper 2 cell cytokine production GO:2000551 2 0.015
regulation of secretion by cell GO:1903530 177 0.015
regulation of intracellular transport GO:0032386 195 0.015
myeloid cell differentiation GO:0030099 117 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
protein lipidation GO:0006497 33 0.014
regulation of protein kinase activity GO:0045859 289 0.014
ameboidal type cell migration GO:0001667 135 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
positive regulation of immune system process GO:0002684 283 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
chromatin organization GO:0006325 351 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
determination of adult lifespan GO:0008340 2 0.014
ncrna metabolic process GO:0034660 108 0.014
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 8 0.014
carbohydrate homeostasis GO:0033500 31 0.013
carbohydrate metabolic process GO:0005975 207 0.013
glucose homeostasis GO:0042593 31 0.013
protein localization to membrane GO:0072657 160 0.013
response to molecule of bacterial origin GO:0002237 82 0.013
nucleotide biosynthetic process GO:0009165 109 0.013
actin filament based process GO:0030029 224 0.012
negative regulation of locomotion GO:0040013 118 0.012
mitochondrion organization GO:0007005 156 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
response to growth factor GO:0070848 205 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
cation homeostasis GO:0055080 189 0.012
mrna processing GO:0006397 133 0.012
protein k11 linked ubiquitination GO:0070979 24 0.012
protein oligomerization GO:0051259 173 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
purine containing compound catabolic process GO:0072523 411 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
regulation of cell motility GO:2000145 299 0.012
positive regulation of catabolic process GO:0009896 310 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
membrane organization GO:0061024 292 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.012
protein acylation GO:0043543 138 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
regulation of membrane potential GO:0042391 95 0.011
nuclear import GO:0051170 106 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
cellular protein complex assembly GO:0043623 188 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
regulation of nik nf kappab signaling GO:1901222 11 0.011
interferon gamma production GO:0032609 39 0.011
negative regulation of cell motility GO:2000146 104 0.011
negative regulation of transferase activity GO:0051348 124 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
double strand break repair GO:0006302 101 0.011
chemotaxis GO:0006935 157 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
purine nucleotide catabolic process GO:0006195 405 0.011
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 7 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
gene silencing GO:0016458 49 0.011
mitotic cell cycle process GO:1903047 286 0.011
visual behavior GO:0007632 2 0.010
regulation of nucleotide metabolic process GO:0006140 269 0.010
gene silencing by mirna GO:0035195 23 0.010
glycoprotein metabolic process GO:0009100 110 0.010
protein glycosylation GO:0006486 62 0.010
hematopoietic progenitor cell differentiation GO:0002244 38 0.010
cellular component morphogenesis GO:0032989 314 0.010

IFIT1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.024
central nervous system disease DOID:331 186 0.012
nervous system disease DOID:863 431 0.012