Homo sapiens

29 known processes

IFIT3

interferon-induced protein with tetratricopeptide repeats 3

(Aliases: GARG-49,IRG2,RIG-G,CIG-49,IFI60,ISG60,IFIT4)

IFIT3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of viral genome replication GO:0045071 35 0.999
Human
intracellular transport of viral protein in host cell GO:0019060 4 0.999
Human
intracellular protein transport in other organism involved in symbiotic interaction GO:0051708 4 0.999
Human
defense response to virus GO:0051607 71 0.999
Human
extracellular transport GO:0006858 4 0.999
Human
viral life cycle GO:0019058 132 0.998
Human
regulation of viral process GO:0050792 103 0.997
Human
negative regulation of defense response to virus by host GO:0050689 4 0.995
Human
viral genome replication GO:0019079 50 0.994
Human
response to interferon alpha GO:0035455 11 0.994
multi organism cellular process GO:0044764 156 0.993
Human
multi organism localization GO:1902579 14 0.992
Human
response to biotic stimulus GO:0009607 276 0.992
cellular response to interferon alpha GO:0035457 4 0.992
regulation of viral genome replication GO:0045069 48 0.991
Human
intracellular transport of virus GO:0075733 14 0.991
Human
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.990
Human
response to cytokine GO:0034097 232 0.989
Human Mouse
interspecies interaction between organisms GO:0044419 156 0.989
Human
response to external biotic stimulus GO:0043207 261 0.988
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.988
Human
regulation of defense response to virus GO:0050688 33 0.985
Human
viral process GO:0016032 146 0.984
Human
response to virus GO:0009615 126 0.983
defense response to other organism GO:0098542 129 0.980
Human
response to other organism GO:0051707 261 0.976
immune effector process GO:0002252 159 0.967
Human
regulation of multi organism process GO:0043900 157 0.966
Human
negative regulation of viral process GO:0048525 66 0.966
Human
transport of virus GO:0046794 14 0.965
Human
defense response GO:0006952 315 0.963
Human
immune response GO:0006955 307 0.958
Human
negative regulation of multi organism process GO:0043901 92 0.941
Human
cytokine production GO:0001816 247 0.932
regulation of defense response GO:0031347 154 0.929
Human
symbiont intracellular protein transport in host GO:0030581 4 0.923
Human
response to dsrna GO:0043331 25 0.918
Human
regulation by virus of viral protein levels in host cell GO:0046719 4 0.916
Human
positive regulation of cell death GO:0010942 263 0.906
Human
regulation of defense response to virus by host GO:0050691 22 0.879
Human
innate immune response GO:0045087 178 0.850
Human
cellular response to cytokine stimulus GO:0071345 181 0.847
Human Mouse
response to exogenous dsrna GO:0043330 10 0.838
Human
cellular response to dsrna GO:0071359 19 0.834
Human
regulation of immune effector process GO:0002697 91 0.830
Human
positive regulation of rig i signaling pathway GO:1900246 4 0.823
multi organism transport GO:0044766 14 0.780
Human
negative regulation of immune effector process GO:0002698 38 0.776
Human
negative regulation of binding GO:0051100 57 0.772
Human
regulation of response to external stimulus GO:0032101 222 0.758
Human
negative regulation of immune system process GO:0002683 136 0.754
Human
positive regulation of programmed cell death GO:0043068 249 0.742
Human
multi organism intracellular transport GO:1902583 14 0.717
Human
negative regulation of defense response to virus GO:0050687 10 0.704
Human
interaction with host GO:0051701 42 0.702
Human
regulation of response to biotic stimulus GO:0002831 55 0.695
Human
negative regulation of catalytic activity GO:0043086 335 0.670
Human
regulation of protein binding GO:0043393 66 0.649
Human
positive regulation of apoptotic process GO:0043065 246 0.648
Human
negative regulation of cell proliferation GO:0008285 228 0.614
cellular response to organic cyclic compound GO:0071407 127 0.562
Human
negative regulation of cell death GO:0060548 345 0.540
positive regulation of multi organism process GO:0043902 56 0.536
Human
cellular response to exogenous dsrna GO:0071360 5 0.530
Human
cellular response to type i interferon GO:0071357 12 0.529
Human
negative regulation of defense response GO:0031348 47 0.528
Human
chemical homeostasis GO:0048878 306 0.496
Human
cellular response to interferon beta GO:0035458 6 0.493
Mouse
intracellular protein transport GO:0006886 270 0.472
Human
response to nitrogen compound GO:1901698 184 0.456
Human
positive regulation of viral process GO:0048524 37 0.452
Human
negative regulation of programmed cell death GO:0043069 321 0.444
regulation of binding GO:0051098 111 0.413
Human
negative regulation of apoptotic process GO:0043066 316 0.397
negative regulation of response to external stimulus GO:0032102 83 0.356
Human
negative regulation of protein binding GO:0032091 35 0.346
Human
positive regulation of immune effector process GO:0002699 40 0.343
pattern recognition receptor signaling pathway GO:0002221 48 0.339
nucleotide biosynthetic process GO:0009165 109 0.308
glycosylation GO:0070085 71 0.254
regulation of rig i signaling pathway GO:0039535 6 0.220
regulation of transferase activity GO:0051338 355 0.209
negative regulation of hydrolase activity GO:0051346 182 0.196
Human
response to organic cyclic compound GO:0014070 204 0.196
Human Mouse
carbohydrate derivative biosynthetic process GO:1901137 207 0.193
regulation of cytokine production GO:0001817 232 0.174
nuclear transport GO:0051169 179 0.155
immune system development GO:0002520 195 0.129
posttranscriptional regulation of gene expression GO:0010608 213 0.123
hemopoiesis GO:0030097 180 0.114
negative regulation of protein metabolic process GO:0051248 391 0.107
negative regulation of response to biotic stimulus GO:0002832 18 0.103
Human
regulation of ribonuclease activity GO:0060700 3 0.101
regulation of cell migration GO:0030334 289 0.101
positive regulation of intracellular protein transport GO:0090316 76 0.100
organophosphate biosynthetic process GO:0090407 163 0.096
posttranscriptional gene silencing GO:0016441 25 0.093
regulation of nuclease activity GO:0032069 11 0.090
positive regulation of immune response GO:0050778 159 0.088
response to type i interferon GO:0034340 14 0.086
Human
rig i signaling pathway GO:0039529 7 0.085
positive regulation of cytokine production GO:0001819 167 0.073
positive regulation of immune system process GO:0002684 283 0.072
cellular macromolecule catabolic process GO:0044265 380 0.070
negative regulation of protein maturation GO:1903318 142 0.065
positive regulation of developmental process GO:0051094 314 0.062
metal ion transport GO:0030001 272 0.061
response to bacterium GO:0009617 144 0.060
mrna metabolic process GO:0016071 175 0.059
glucose metabolic process GO:0006006 45 0.059
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.057
nucleoside phosphate biosynthetic process GO:1901293 109 0.056
regulation of protein transport GO:0051223 213 0.056
regulation of cell differentiation GO:0045595 393 0.053
cellular response to nitrogen compound GO:1901699 144 0.053
Human
regulation of mda 5 signaling pathway GO:0039533 4 0.051
regulation of locomotion GO:0040012 329 0.051
positive regulation of defense response GO:0031349 87 0.051
negative regulation of cellular protein metabolic process GO:0032269 353 0.050
protein maturation GO:0051604 233 0.048
organonitrogen compound biosynthetic process GO:1901566 200 0.046
positive regulation of proteolysis GO:0045862 142 0.046
positive regulation of type i interferon production GO:0032481 20 0.045
regulation of apoptotic signaling pathway GO:2001233 175 0.044
regulation of nucleocytoplasmic transport GO:0046822 98 0.041
regulation of secretion by cell GO:1903530 177 0.041
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.039
regulation of protein localization GO:0032880 296 0.039
rna interference GO:0016246 4 0.038
positive regulation of cellular component organization GO:0051130 376 0.037
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.036
regulation of establishment of protein localization GO:0070201 242 0.036
negative regulation of peptidase activity GO:0010466 91 0.034
glycoprotein biosynthetic process GO:0009101 91 0.034
response to molecule of bacterial origin GO:0002237 82 0.034
protein targeting to nucleus GO:0044744 104 0.034
rna processing GO:0006396 255 0.033
negative regulation of multicellular organismal process GO:0051241 317 0.032
immune response activating signal transduction GO:0002757 90 0.031
regulation of intracellular transport GO:0032386 195 0.030
regulation of innate immune response GO:0045088 97 0.030
positive regulation of cell differentiation GO:0045597 211 0.029
positive regulation of innate immune response GO:0045089 79 0.029
positive regulation of viral genome replication GO:0045070 15 0.029
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.029
response to interferon beta GO:0035456 11 0.028
Mouse
regulation of immune response GO:0050776 201 0.027
mapk cascade GO:0000165 288 0.027
organophosphate catabolic process GO:0046434 430 0.027
positive regulation of transferase activity GO:0051347 227 0.027
positive regulation of phosphorylation GO:0042327 394 0.026
secretion by cell GO:0032940 226 0.026
lipoprotein metabolic process GO:0042157 42 0.026
positive regulation of interferon beta production GO:0032728 17 0.026
cellular response to oxygen containing compound GO:1901701 276 0.026
receptor metabolic process GO:0043112 81 0.025
protein oligomerization GO:0051259 173 0.025
modification dependent macromolecule catabolic process GO:0043632 212 0.025
protein catabolic process GO:0030163 325 0.024
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 8 0.024
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.024
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039532 3 0.024
secretion GO:0046903 254 0.024
response to abiotic stimulus GO:0009628 336 0.024
cellular cation homeostasis GO:0030003 163 0.023
cellular protein catabolic process GO:0044257 261 0.022
cytoplasmic transport GO:0016482 379 0.022
single organism carbohydrate metabolic process GO:0044723 193 0.021
response to interferon gamma GO:0034341 39 0.021
regulation of ion transport GO:0043269 189 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
negative regulation of cell motility GO:2000146 104 0.021
cellular response to molecule of bacterial origin GO:0071219 62 0.020
positive regulation of homeostatic process GO:0032846 47 0.020
positive regulation of response to external stimulus GO:0032103 88 0.020
regulation of mapk cascade GO:0043408 262 0.020
regulation of helicase activity GO:0051095 8 0.020
Human
positive regulation of hydrolase activity GO:0051345 331 0.020
negative regulation of transferase activity GO:0051348 124 0.019
calcium ion homeostasis GO:0055074 122 0.019
regulation of cytoskeleton organization GO:0051493 177 0.019
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.019
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 7 0.018
release of cytochrome c from mitochondria GO:0001836 35 0.018
single organism cellular localization GO:1902580 332 0.018
negative regulation of complement activation lectin pathway GO:0001869 2 0.018
ncrna metabolic process GO:0034660 108 0.018
cardiovascular system development GO:0072358 262 0.018
macromolecule glycosylation GO:0043413 63 0.018
activation of innate immune response GO:0002218 55 0.018
negative regulation of proteolysis GO:0045861 132 0.017
protein acylation GO:0043543 138 0.017
leukocyte differentiation GO:0002521 98 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.016
mda 5 signaling pathway GO:0039530 4 0.016
purine nucleotide biosynthetic process GO:0006164 84 0.016
purine containing compound biosynthetic process GO:0072522 88 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
intracellular receptor signaling pathway GO:0030522 104 0.016
regulation of myeloid cell differentiation GO:0045637 81 0.016
regulation of protein catabolic process GO:0042176 155 0.016
regulation of cellular response to stress GO:0080135 244 0.016
immune response regulating signaling pathway GO:0002764 97 0.015
regulation of homeostatic process GO:0032844 121 0.015
negative regulation of locomotion GO:0040013 118 0.015
neurological system process GO:0050877 163 0.015
chemotaxis GO:0006935 157 0.015
apoptotic signaling pathway GO:0097190 268 0.015
myeloid cell differentiation GO:0030099 117 0.015
negative regulation of transport GO:0051051 176 0.015
activation of immune response GO:0002253 114 0.015
cation transport GO:0006812 331 0.015
regulation of protein secretion GO:0050708 86 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
response to oxygen containing compound GO:1901700 369 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.014
circulatory system development GO:0072359 262 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
regulation of protein localization to nucleus GO:1900180 85 0.014
negative regulation of protein modification process GO:0031400 200 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
glycoprotein metabolic process GO:0009100 110 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.013
nucleotide catabolic process GO:0009166 408 0.013
cell cycle arrest GO:0007050 71 0.013
protein localization to membrane GO:0072657 160 0.013
vasodilation GO:0042311 4 0.013
single organism nuclear import GO:1902593 104 0.013
regulation of protein kinase activity GO:0045859 289 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.012
epithelial cell migration GO:0010631 119 0.012
protein glycosylation GO:0006486 62 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
cellular response to lipid GO:0071396 127 0.012
vasculature development GO:0001944 181 0.012
taxis GO:0042330 157 0.012
glucose homeostasis GO:0042593 31 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
extrinsic apoptotic signaling pathway GO:0097191 119 0.012
regulation of cellular component movement GO:0051270 334 0.012
regulation of cell cycle GO:0051726 393 0.012
response to lipid GO:0033993 206 0.012
calcium ion import GO:0070509 23 0.012
vesicle mediated transport GO:0016192 371 0.011
positive regulation of kinase activity GO:0033674 204 0.011
regulation of t helper 2 cell cytokine production GO:2000551 2 0.011
negative regulation of apoptotic signaling pathway GO:2001234 97 0.011
response to radiation GO:0009314 151 0.011
protein import GO:0017038 130 0.011
divalent metal ion transport GO:0070838 152 0.011
protein localization to organelle GO:0033365 280 0.011
blood vessel development GO:0001568 172 0.011
transmembrane transport GO:0055085 399 0.011
negative regulation of developmental process GO:0051093 247 0.011
defense response to bacterium GO:0042742 63 0.011
protein export from nucleus GO:0006611 29 0.011
negative regulation of protein ubiquitination GO:0031397 35 0.011
stress activated mapk cascade GO:0051403 93 0.011
regulation of peptidase activity GO:0052547 180 0.011
protein ubiquitination GO:0016567 314 0.011
isg15 protein conjugation GO:0032020 5 0.011
metal ion homeostasis GO:0055065 169 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
endothelial cell migration GO:0043542 86 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
protein k11 linked ubiquitination GO:0070979 24 0.011
negative regulation of cell cycle GO:0045786 193 0.011
gene silencing by rna GO:0031047 26 0.010
regulation of hematopoietic progenitor cell differentiation GO:1901532 24 0.010
positive regulation of transport GO:0051050 336 0.010
protein targeting GO:0006605 187 0.010
positive regulation of protein phosphorylation GO:0001934 313 0.010
cellular protein complex assembly GO:0043623 188 0.010
nucleoside catabolic process GO:0009164 408 0.010
positive regulation of organelle organization GO:0010638 195 0.010
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.010
ion homeostasis GO:0050801 230 0.010
negative regulation of phosphate metabolic process GO:0045936 267 0.010

IFIT3 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.040
acquired metabolic disease DOID:0060158 58 0.040
central nervous system disease DOID:331 186 0.018
nervous system disease DOID:863 431 0.018