|
|
epithelium development
|
GO:0060429 |
227 |
0.863
|
Zebrafish |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.841
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.833
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.798
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.793
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.793
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.770
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.712
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.709
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.679
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.677
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.653
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.652
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.617
|
Human Zebrafish Mouse |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.602
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.579
|
Mouse |
|
|
negative regulation of gastrulation
|
GO:2000542 |
4 |
0.577
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.556
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.554
|
Mouse |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.553
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.552
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.530
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.524
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.485
|
Zebrafish |
|
|
defense response
|
GO:0006952 |
315 |
0.478
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.466
|
Zebrafish |
|
|
response to wounding
|
GO:0009611 |
168 |
0.451
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.424
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.423
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.406
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.402
|
Human |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.396
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.395
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.390
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.390
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.387
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.384
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.381
|
Zebrafish |
|
|
response to lipid
|
GO:0033993 |
206 |
0.372
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.372
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.367
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.351
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.350
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.349
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.341
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.340
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.339
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.323
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.318
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.310
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.302
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.296
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.288
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.285
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.284
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.281
|
Zebrafish |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.279
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.273
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.266
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.261
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.255
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.254
|
Human |
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.246
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.245
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.242
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.241
|
|
|
|
positive regulation of keratinocyte migration
|
GO:0051549 |
4 |
0.237
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.232
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.232
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.231
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.230
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.228
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.226
|
Human |
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.225
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.224
|
Zebrafish |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.220
|
|
|
|
system process
|
GO:0003008 |
349 |
0.219
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.213
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.208
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.206
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.202
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.201
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.196
|
|
|
|
replacement ossification
|
GO:0036075 |
1 |
0.194
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.193
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.192
|
Zebrafish |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.192
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.191
|
Human |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.190
|
Human Zebrafish Mouse |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.187
|
|
|
|
regulation of keratinocyte migration
|
GO:0051547 |
4 |
0.186
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.186
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.184
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.183
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.182
|
Human |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.181
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.180
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.176
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.175
|
Zebrafish |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.174
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.171
|
Mouse |
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.171
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.170
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.168
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.167
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.167
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.163
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.162
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.162
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.162
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.161
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.160
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.156
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.154
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.154
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.154
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.152
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.151
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.149
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.148
|
Human |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.146
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.144
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.144
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.142
|
|
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.137
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.135
|
Zebrafish |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.134
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.134
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.133
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.132
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.130
|
Human |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.130
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.129
|
|
|
|
bone trabecula formation
|
GO:0060346 |
1 |
0.129
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.129
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.127
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.126
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.126
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.125
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.125
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.124
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.124
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.124
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.123
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.123
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.121
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.116
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.115
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.115
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.115
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.114
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.114
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.114
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.114
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.113
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.113
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.113
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.112
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.112
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.110
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.110
|
Mouse |
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.109
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.109
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.109
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.107
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.107
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.106
|
Human |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.106
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.103
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.103
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.102
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.101
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.101
|
Mouse |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.100
|
|
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.099
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.099
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.098
|
|
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.098
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.098
|
|
|
|
growth
|
GO:0040007 |
202 |
0.095
|
Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.095
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.095
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.095
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.094
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.092
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.090
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.090
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.089
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.088
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.087
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.086
|
Mouse |
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.086
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.086
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.086
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.085
|
|
|
|
negative regulation of endodermal cell differentiation
|
GO:1903225 |
2 |
0.085
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.085
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.085
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.084
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.084
|
Mouse |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.084
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.083
|
Human |
|
|
response to metal ion
|
GO:0010038 |
84 |
0.082
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.082
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.081
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.080
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.079
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.079
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.077
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.077
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.076
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.076
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.076
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.075
|
|
|
|
bone trabecula morphogenesis
|
GO:0061430 |
1 |
0.075
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.075
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.074
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.074
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.074
|
|
|
|
hemoglobin biosynthetic process
|
GO:0042541 |
3 |
0.073
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.073
|
|
|
|
positive regulation of steroid hormone biosynthetic process
|
GO:0090031 |
2 |
0.072
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.071
|
|
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
22 |
0.071
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.071
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.071
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.071
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.071
|
|
|
|
response to hyperoxia
|
GO:0055093 |
4 |
0.070
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.070
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.069
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.069
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.069
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.069
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.068
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.068
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.067
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.067
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.067
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.065
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.065
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.065
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.065
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.065
|
|
|
|
epiboly involved in wound healing
|
GO:0090505 |
8 |
0.064
|
|
|
|
regulation of endodermal cell differentiation
|
GO:1903224 |
3 |
0.064
|
|
|
|
elastic fiber assembly
|
GO:0048251 |
3 |
0.064
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.063
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.063
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.063
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.063
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.063
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.063
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.063
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.063
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.062
|
Mouse |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.062
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.061
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.061
|
|
|
|
endochondral ossification
|
GO:0001958 |
1 |
0.061
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.060
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
27 |
0.059
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.059
|
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.058
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.057
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.057
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.057
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
2 |
0.057
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.057
|
Mouse |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.056
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.056
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.056
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.056
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.056
|
|
|
|
detection of mechanical stimulus
|
GO:0050982 |
4 |
0.055
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.054
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.054
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.054
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.053
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.052
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.052
|
|
|
|
odontogenesis
|
GO:0042476 |
25 |
0.052
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.051
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.051
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.051
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.050
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.050
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.050
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.049
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.049
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.049
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.049
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.049
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.049
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.049
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.049
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.048
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.048
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.048
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.048
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.048
|
|
|
|
response to mercury ion
|
GO:0046689 |
4 |
0.048
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.048
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.047
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.047
|
Human |
|
|
collagen metabolic process
|
GO:0032963 |
28 |
0.047
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.046
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.046
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.046
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.045
|
|
|
|
detection of mechanical stimulus involved in sensory perception
|
GO:0050974 |
1 |
0.045
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.045
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.045
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.045
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.044
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.044
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.044
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.044
|
|
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.043
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.043
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.043
|
|
|
|
cellular response to camp
|
GO:0071320 |
21 |
0.043
|
Human |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.043
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.043
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.043
|
|
|
|
embryonic skeletal joint development
|
GO:0072498 |
2 |
0.043
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.043
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.043
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.042
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.042
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.042
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.042
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.042
|
|
|
|
multicellular organismal macromolecule metabolic process
|
GO:0044259 |
29 |
0.042
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.041
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.041
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.041
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.040
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.040
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.040
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.040
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.040
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.040
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.040
|
|
|
|
positive regulation of plasminogen activation
|
GO:0010756 |
3 |
0.040
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.039
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.039
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.039
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.039
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.039
|
Zebrafish |
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.039
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.039
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.039
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.039
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.039
|
|
|
|
cartilage condensation
|
GO:0001502 |
1 |
0.039
|
|
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.038
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.038
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.038
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.038
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.038
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.038
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.038
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.038
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.038
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.038
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.037
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.037
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.037
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.037
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.037
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.037
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.037
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.036
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.036
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.036
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.036
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.036
|
Human |
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.036
|
Human |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.036
|
|
|
|
macrophage fusion
|
GO:0034238 |
1 |
0.035
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.035
|
|
|
|
soft palate development
|
GO:0060023 |
3 |
0.035
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.035
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.035
|
Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.035
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.035
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.035
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.035
|
|
|
|
head development
|
GO:0060322 |
108 |
0.035
|
|
|
|
receptor transactivation
|
GO:0035624 |
4 |
0.034
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.034
|
|
|
|
monocyte activation
|
GO:0042117 |
3 |
0.034
|
|
|
|
response to epidermal growth factor
|
GO:0070849 |
14 |
0.034
|
|
|
|
epiboly
|
GO:0090504 |
9 |
0.033
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.033
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.033
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.033
|
|
|
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.033
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.033
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.033
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.033
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.032
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.032
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.032
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.032
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.032
|
|
|
|
regulation of lymphocyte chemotaxis
|
GO:1901623 |
12 |
0.032
|
|
|
|
bone development
|
GO:0060348 |
26 |
0.032
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.032
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.032
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.032
|
Zebrafish |
|
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.032
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.032
|
|
|
|
positive regulation of mesenchymal stem cell differentiation
|
GO:2000741 |
4 |
0.032
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.031
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.031
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.031
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.031
|
|
|
|
striated muscle cell development
|
GO:0055002 |
27 |
0.031
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.031
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.031
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.031
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.031
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.031
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.030
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.030
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.030
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.030
|
Zebrafish |
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.030
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.030
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.030
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.029
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.029
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.029
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.029
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.029
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.029
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.029
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.029
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.029
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.029
|
Human |
|
|
gland morphogenesis
|
GO:0022612 |
8 |
0.029
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.029
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.029
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.029
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.029
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.029
|
Zebrafish |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.029
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.028
|
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.028
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.028
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.028
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.028
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.028
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.027
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.027
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.027
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.027
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.027
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.027
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.027
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.027
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.027
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.027
|
Human |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.027
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.026
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.026
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.026
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.026
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.026
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.026
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.026
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.026
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.026
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.026
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.026
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.026
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
15 |
0.026
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.025
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.025
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.025
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.025
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.025
|
|
