|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
1.000
|
Human |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
1.000
|
Human |
|
|
detection of muramyl dipeptide
|
GO:0032498 |
1 |
1.000
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
1.000
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
1.000
|
Human Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.999
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.999
|
Fly |
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.997
|
Fly |
|
|
defense response to virus
|
GO:0051607 |
71 |
0.997
|
Fly |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.996
|
|
|
|
serine phosphorylation of stat protein
|
GO:0042501 |
4 |
0.995
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.994
|
|
|
|
regulation of interferon beta production
|
GO:0032648 |
22 |
0.994
|
Human |
|
|
i kappab phosphorylation
|
GO:0007252 |
7 |
0.992
|
Mouse |
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.991
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.990
|
Fly |
|
|
response to virus
|
GO:0009615 |
126 |
0.990
|
Fly |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.990
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.988
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.987
|
Fly |
|
|
amide biosynthetic process
|
GO:0043604 |
15 |
0.986
|
Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.985
|
Human |
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.985
|
Fly |
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
4 |
0.985
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.984
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.984
|
Human |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.982
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.980
|
Rat |
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.980
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.979
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.976
|
|
|
|
activation of jnkk activity
|
GO:0007256 |
1 |
0.976
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.972
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
12 |
0.972
|
Human |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.968
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
3 |
0.966
|
Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.966
|
Fly |
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.964
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.960
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.959
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.958
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.950
|
Fly |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.948
|
Human |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.947
|
Human |
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.937
|
Fly |
|
|
regulation of defense response to virus by host
|
GO:0050691 |
22 |
0.935
|
Fly |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.935
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.933
|
Fly |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.931
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.928
|
Rat |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.926
|
Fly |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.926
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.924
|
Fly |
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
12 |
0.923
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.923
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.921
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.915
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.912
|
|
|
|
positive regulation of mhc class i biosynthetic process
|
GO:0045345 |
4 |
0.912
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
11 |
0.911
|
Human |
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.911
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.910
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.910
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.905
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.903
|
Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.902
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.897
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.894
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.894
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.881
|
Mouse |
|
|
positive regulation of interleukin 1 beta secretion
|
GO:0050718 |
11 |
0.871
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.869
|
Fly |
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.868
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.867
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.863
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.859
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.859
|
Fly |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.853
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.852
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.847
|
Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.844
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.836
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.833
|
Fly |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.828
|
Fly |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.828
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.826
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.824
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.819
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.817
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.814
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.811
|
Fly |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.809
|
Fly |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.799
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.799
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.798
|
Human |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.795
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.795
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.783
|
Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.781
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.779
|
Rat |
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
9 |
0.776
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.776
|
Mouse |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.775
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.774
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
2 |
0.769
|
Fly |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.768
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.766
|
|
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
14 |
0.765
|
Fly |
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
1 |
0.764
|
Fly |
|
|
nf kappab import into nucleus
|
GO:0042348 |
22 |
0.752
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.748
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.748
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.726
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.724
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.722
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.721
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.721
|
|
|
|
translation
|
GO:0006412 |
132 |
0.718
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.718
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.716
|
|
|
|
positive regulation of interleukin 1 beta production
|
GO:0032731 |
13 |
0.716
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.716
|
Fly |
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
4 |
0.708
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.704
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.698
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.693
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.682
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.682
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.679
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.676
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.667
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.664
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.662
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.647
|
|
|
|
interleukin 1 production
|
GO:0032612 |
26 |
0.644
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.640
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.636
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.635
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.628
|
|
|
|
regulation of interferon alpha production
|
GO:0032647 |
11 |
0.626
|
Human |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.618
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.617
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.616
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.609
|
Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.606
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.606
|
Rat |
|
|
regulation of type i interferon production
|
GO:0032479 |
26 |
0.600
|
Human |
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.597
|
Fly |
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.596
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
12 |
0.594
|
|
|
|
epiboly involved in gastrulation with mouth forming second
|
GO:0055113 |
1 |
0.593
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.589
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.584
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.583
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.582
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.579
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.572
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.567
|
Fly |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.564
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.561
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.558
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.554
|
Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.552
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.546
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
24 |
0.537
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.534
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.534
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.527
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
26 |
0.526
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.524
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
22 |
0.524
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.514
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.510
|
Human |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.494
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.494
|
|
|
|
antifungal humoral response
|
GO:0019732 |
2 |
0.490
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.481
|
|
|
|
interferon beta production
|
GO:0032608 |
23 |
0.481
|
Human |
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.478
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.472
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.461
|
Fly |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.459
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.454
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
11 |
0.452
|
|
|
|
activation of nf kappab inducing kinase activity
|
GO:0007250 |
9 |
0.450
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.447
|
|
|
|
negative regulation of lipid storage
|
GO:0010888 |
11 |
0.438
|
|
|
|
fat soluble vitamin metabolic process
|
GO:0006775 |
19 |
0.430
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.423
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.422
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.420
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.420
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.412
|
Fly |
|
|
somitogenesis
|
GO:0001756 |
2 |
0.412
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.405
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.404
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.404
|
Rat |
|
|
protein import into nucleus translocation
|
GO:0000060 |
22 |
0.399
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.390
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.388
|
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.384
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.383
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.381
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.379
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.374
|
|
|
|
detection of peptidoglycan
|
GO:0032499 |
1 |
0.373
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.370
|
|
|
|
cholesterol transport
|
GO:0030301 |
39 |
0.370
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.370
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.367
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.365
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.363
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.355
|
|
|
|
system process
|
GO:0003008 |
349 |
0.353
|
Rat |
|
|
vitamin d metabolic process
|
GO:0042359 |
10 |
0.350
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.348
|
|
|
|
type i interferon production
|
GO:0032606 |
27 |
0.348
|
Human |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.340
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
37 |
0.337
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.337
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
15 |
0.335
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.334
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.334
|
Mouse |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.333
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.333
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.332
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.332
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.323
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.317
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.313
|
|
|
|
lactation
|
GO:0007595 |
3 |
0.313
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.312
|
|
|
|
regulation of mhc class i biosynthetic process
|
GO:0045343 |
4 |
0.304
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.296
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.294
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.291
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.289
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.285
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.281
|
|
|
|
negative regulation of interleukin 1 secretion
|
GO:0050711 |
4 |
0.279
|
|
|
|
n terminal protein amino acid modification
|
GO:0031365 |
13 |
0.274
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.270
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.269
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.268
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.267
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.267
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.265
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.262
|
|
|
|
sterol transport
|
GO:0015918 |
39 |
0.260
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
18 |
0.259
|
|
|
|
negative regulation of macrophage derived foam cell differentiation
|
GO:0010745 |
7 |
0.258
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.255
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.254
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.254
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.253
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.248
|
|
|
|
regulation of nf kappab import into nucleus
|
GO:0042345 |
22 |
0.245
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.245
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.242
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.238
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.235
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.232
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.230
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.230
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.229
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.227
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.226
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.224
|
|
|
|
positive regulation of type i interferon production
|
GO:0032481 |
20 |
0.223
|
Human |
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
34 |
0.223
|
|
|
|
negative regulation of transcription factor import into nucleus
|
GO:0042992 |
17 |
0.223
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.222
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
24 |
0.220
|
Fly |
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.218
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.215
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.214
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.209
|
|
|
|
interferon alpha production
|
GO:0032607 |
11 |
0.208
|
Human |
|
|
regulation of macrophage derived foam cell differentiation
|
GO:0010743 |
14 |
0.207
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.205
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.203
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.202
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.201
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.201
|
|
|
|
response to muramyl dipeptide
|
GO:0032495 |
4 |
0.200
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.199
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
17 |
0.197
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.196
|
|
|
|
positive regulation of interleukin 1 production
|
GO:0032732 |
14 |
0.195
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.193
|
|
|
|
cellular response to muramyl dipeptide
|
GO:0071225 |
3 |
0.193
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.193
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.192
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.192
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
21 |
0.192
|
|
|
|
detection of chemical stimulus
|
GO:0009593 |
55 |
0.192
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.191
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.190
|
Fly |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.188
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.186
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.185
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.184
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.181
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.181
|
|
|
|
nucleotide binding domain leucine rich repeat containing receptor signaling pathway
|
GO:0035872 |
5 |
0.179
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.178
|
|
|
|
peptide metabolic process
|
GO:0006518 |
51 |
0.177
|
Fly |
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.175
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.175
|
Fly |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.175
|
|
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.174
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.172
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.172
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.171
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.168
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.168
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.165
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.163
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.161
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.161
|
|
|
|
regulation of interleukin 1 secretion
|
GO:0050704 |
14 |
0.159
|
|
|
|
response to type i interferon
|
GO:0034340 |
14 |
0.158
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.157
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
7 |
0.156
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
3 |
0.154
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.154
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.153
|
Rat |
|
|
negative regulation of interleukin 8 biosynthetic process
|
GO:0045415 |
3 |
0.150
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.149
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.148
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.148
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.146
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.144
|
|
|
|
cytoplasmic sequestering of nf kappab
|
GO:0007253 |
7 |
0.144
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.144
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.142
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.141
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.141
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.140
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.140
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.140
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.139
|
Fly |
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.138
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.138
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.137
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.137
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.136
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.136
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.135
|
Fly |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.134
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.132
|
|
|
|
regulation of response to interferon gamma
|
GO:0060330 |
7 |
0.130
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.129
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.129
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.129
|
|
|
|
cerebral cortex development
|
GO:0021987 |
10 |
0.128
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.128
|
|
|
|
negative regulation of interleukin 1 beta production
|
GO:0032691 |
6 |
0.126
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.126
|
|
|
|
dicarboxylic acid metabolic process
|
GO:0043648 |
29 |
0.126
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.125
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.125
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.123
|
|
|
|
odontogenesis
|
GO:0042476 |
25 |
0.122
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.121
|
Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.120
|
|
|
|
positive regulation of response to cytokine stimulus
|
GO:0060760 |
13 |
0.118
|
|
|
|
protein complex localization
|
GO:0031503 |
31 |
0.116
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.116
|
|
|
|
regulation of transcription by galactose
|
GO:0000409 |
1 |
0.116
|
|
|
|
macrophage derived foam cell differentiation
|
GO:0010742 |
15 |
0.116
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.115
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
1 |
0.115
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.114
|
|
|
|
cytoplasmic sequestering of protein
|
GO:0051220 |
12 |
0.113
|
|
|
|
carbon catabolite activation of transcription from rna polymerase ii promoter
|
GO:0000436 |
3 |
0.113
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.113
|
|
|
|
negative regulation of interleukin 6 biosynthetic process
|
GO:0045409 |
3 |
0.112
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.111
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.111
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.111
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.110
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.110
|
Mouse |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.109
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.108
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.108
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.108
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
18 |
0.107
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.107
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.107
|
Fly |
|
|
interleukin 17 production
|
GO:0032620 |
12 |
0.107
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.106
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.106
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.106
|
|
|
|
retina homeostasis
|
GO:0001895 |
42 |
0.104
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.104
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.103
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.103
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.103
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
44 |
0.103
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.102
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.101
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.100
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.100
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.099
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.098
|
|
|
|
regulation of cellular amide metabolic process
|
GO:0034248 |
9 |
0.095
|
Fly |
|
|
response to peptidoglycan
|
GO:0032494 |
3 |
0.094
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.094
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
21 |
0.092
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.092
|
|
|
|
glycosylation
|
GO:0070085 |
71 |
0.092
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
12 |
0.092
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.091
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.091
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.090
|
|
|
|
toll signaling pathway
|
GO:0008063 |
2 |
0.088
|
|
|
|
positive regulation of nf kappab import into nucleus
|
GO:0042346 |
13 |
0.088
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.088
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.087
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.087
|
|
|
|
negative regulation of interleukin 1 beta secretion
|
GO:0050713 |
2 |
0.086
|
|
|
|
regulation of sterol transport
|
GO:0032371 |
21 |
0.086
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.086
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.086
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.085
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.085
|
|
|
|
protein k33 linked ubiquitination
|
GO:1990390 |
1 |
0.085
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.084
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.084
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
21 |
0.083
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.083
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.083
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.083
|
|
|
|
response to interferon gamma
|
GO:0034341 |
39 |
0.082
|
|
|
|
response to thyroid hormone
|
GO:0097066 |
9 |
0.082
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.082
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.082
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.082
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.081
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.081
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.081
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.081
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.081
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.081
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.081
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.080
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.080
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.080
|
Rat |
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.080
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.080
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.079
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.079
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.079
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.078
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.078
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.078
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.077
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.077
|
Mouse |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.076
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.076
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.076
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.076
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.075
|
|
|
|
carbon catabolite regulation of transcription from rna polymerase ii promoter
|
GO:0000429 |
3 |
0.075
|
|
|
|
mammary gland development
|
GO:0030879 |
17 |
0.075
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.074
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.074
|
|
|
|
vitamin metabolic process
|
GO:0006766 |
26 |
0.074
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.073
|
|
|
|
regulation of nik nf kappab signaling
|
GO:1901222 |
11 |
0.073
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.073
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.072
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.072
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.072
|
|
|
|
positive regulation of response to biotic stimulus
|
GO:0002833 |
18 |
0.072
|
Fly |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.071
|
|
|
|
negative regulation of tor signaling
|
GO:0032007 |
11 |
0.070
|
|
|
|
negative regulation of cytokine biosynthetic process
|
GO:0042036 |
11 |
0.070
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.070
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.069
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.069
|
Mouse |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.068
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.068
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.068
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.067
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.067
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.067
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.067
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.067
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.067
|
|
