|
|
ciliary neurotrophic factor mediated signaling pathway
|
GO:0070120 |
5 |
1.000
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
1.000
|
|
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.999
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.999
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.997
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.997
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.997
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.990
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.990
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.990
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.988
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.985
|
|
|
|
interleukin 6 mediated signaling pathway
|
GO:0070102 |
7 |
0.982
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.981
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.977
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.977
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.976
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.975
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.975
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.969
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.940
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.935
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.929
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.924
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.897
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.895
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.873
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.832
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.826
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.808
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.805
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.804
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.798
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.797
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.772
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.755
|
|
|
|
interleukin 27 mediated signaling pathway
|
GO:0070106 |
1 |
0.743
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.738
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.731
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.727
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
11 |
0.710
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.698
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.668
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.665
|
Rat |
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.645
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.640
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
14 |
0.632
|
|
|
|
negative regulation of collagen metabolic process
|
GO:0010713 |
3 |
0.618
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.604
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.603
|
Rat |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.599
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.598
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.595
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.560
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.545
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.522
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.487
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.484
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.447
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.446
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.440
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.431
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.430
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.396
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.372
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.365
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.363
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.362
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.361
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.355
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.352
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.347
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.344
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.343
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.340
|
Rat |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.340
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.331
|
Zebrafish Mouse |
|
|
chemokine production
|
GO:0032602 |
32 |
0.327
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.324
|
Human |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.319
|
|
|
|
negative regulation of multicellular organismal metabolic process
|
GO:0044252 |
3 |
0.314
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.308
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.299
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.295
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.293
|
Rat |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.292
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.288
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.286
|
Human |
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
0.285
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.285
|
|
|
|
positive regulation of peptidyl serine phosphorylation of stat protein
|
GO:0033141 |
3 |
0.283
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.282
|
Human |
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.281
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.276
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.270
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.266
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.263
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
0.258
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.258
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.254
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.251
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.248
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.246
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
3 |
0.246
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.243
|
|
|
|
regulation of peptidyl serine phosphorylation of stat protein
|
GO:0033139 |
3 |
0.242
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.237
|
Mouse |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.229
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.227
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.226
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.225
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.221
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.221
|
Zebrafish Mouse |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.218
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.208
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.204
|
Zebrafish |
|
|
hormone secretion
|
GO:0046879 |
65 |
0.202
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.197
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.185
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.183
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.175
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.174
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.173
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.173
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
7 |
0.173
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
11 |
0.171
|
|
|
|
macrophage fusion
|
GO:0034238 |
1 |
0.169
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.169
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.166
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.164
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.164
|
Human |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.164
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.163
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.163
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.159
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.153
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.151
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.150
|
|
|
|
oncostatin m mediated signaling pathway
|
GO:0038165 |
3 |
0.147
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.145
|
Rat |
|
|
system process
|
GO:0003008 |
349 |
0.145
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.143
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.141
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.141
|
Rat |
|
|
interleukin 12 mediated signaling pathway
|
GO:0035722 |
3 |
0.140
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.140
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.139
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.139
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.138
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.138
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.137
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.134
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.134
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.133
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.132
|
Zebrafish |
|
|
response to other organism
|
GO:0051707 |
261 |
0.128
|
|
|
|
leukemia inhibitory factor signaling pathway
|
GO:0048861 |
3 |
0.127
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.126
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.126
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.123
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.123
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.122
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.121
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.120
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.119
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.118
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.117
|
|
|
|
negative regulation of collagen biosynthetic process
|
GO:0032966 |
2 |
0.115
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.115
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.115
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.115
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.115
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.115
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.114
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
2 |
0.112
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.111
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.110
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.109
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.107
|
Mouse |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.107
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.106
|
|
|
|
cellular response to interleukin 12
|
GO:0071349 |
3 |
0.106
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.105
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.105
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.103
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.103
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.103
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.098
|
|
|
|
response to growth hormone
|
GO:0060416 |
11 |
0.098
|
|
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
14 |
0.098
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.098
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.097
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.097
|
|
|
|
response to interleukin 6
|
GO:0070741 |
15 |
0.097
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.095
|
Zebrafish Mouse |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.095
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.092
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.088
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.087
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.087
|
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.087
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.086
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.085
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.085
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.084
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.084
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.083
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.083
|
|
|
|
growth hormone receptor signaling pathway
|
GO:0060396 |
10 |
0.082
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.082
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.082
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.082
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.081
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.080
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.080
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.079
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.079
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.079
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.079
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.079
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.079
|
Human |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.078
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.078
|
Rat |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.078
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.077
|
Zebrafish |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.077
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.077
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.075
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.075
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.075
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.075
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.075
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.074
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.074
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.073
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.073
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.072
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.071
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.071
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.071
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.071
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.069
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.068
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.068
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.068
|
Zebrafish |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.068
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.067
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.067
|
|
|
|
negative regulation of hydrogen peroxide metabolic process
|
GO:0010727 |
3 |
0.067
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.066
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.066
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.066
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.066
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.065
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.065
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.065
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.063
|
Rat |
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.063
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.063
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.063
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.062
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.062
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.061
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.061
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.061
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.061
|
|
|
|
cortisol secretion
|
GO:0043400 |
4 |
0.061
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.061
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.060
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.059
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.058
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.058
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.057
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.057
|
Zebrafish |
|
|
response to peptide
|
GO:1901652 |
65 |
0.057
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.056
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.055
|
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.055
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.055
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.055
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.055
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.054
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.054
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.054
|
Zebrafish |
|
|
regeneration
|
GO:0031099 |
4 |
0.054
|
Zebrafish |
|
|
response to glucocorticoid
|
GO:0051384 |
13 |
0.054
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.053
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.053
|
Human |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.053
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
42 |
0.053
|
|
|
|
memory
|
GO:0007613 |
3 |
0.053
|
|
|
|
regulation of astrocyte differentiation
|
GO:0048710 |
3 |
0.052
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.052
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.052
|
|
|
|
regulation of neuron migration
|
GO:2001222 |
3 |
0.052
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.052
|
Zebrafish |
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.052
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.051
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.051
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.050
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.050
|
Human |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.050
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.050
|
|
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
3 |
0.049
|
|
|
|
growth
|
GO:0040007 |
202 |
0.049
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.049
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.048
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.048
|
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.048
|
|
|
|
negative regulation of reactive oxygen species biosynthetic process
|
GO:1903427 |
1 |
0.048
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.048
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.047
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.047
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.047
|
|
|
|
metanephric nephron tubule development
|
GO:0072234 |
3 |
0.047
|
|
|
|
negative regulation of hormone secretion
|
GO:0046888 |
15 |
0.047
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.047
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.046
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.046
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.046
|
Human |
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.046
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.046
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.045
|
|
|
|
response to interleukin 13
|
GO:0035962 |
4 |
0.045
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.044
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.044
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.044
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.044
|
Zebrafish Mouse |
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.044
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.044
|
Zebrafish |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.043
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.043
|
|
|
|
blood vessel remodeling
|
GO:0001974 |
2 |
0.043
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.043
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.043
|
|
|
|
renal vesicle development
|
GO:0072087 |
4 |
0.043
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.043
|
|
|
|
positive regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042511 |
8 |
0.042
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.042
|
Zebrafish |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.042
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.042
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.041
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.041
|
|
|
|
negative regulation of blood circulation
|
GO:1903523 |
4 |
0.041
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.041
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.041
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.041
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.041
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.041
|
Zebrafish |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.041
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.040
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.040
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
3 |
0.040
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.040
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.040
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.040
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.040
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.040
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.040
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.040
|
Rat |
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.040
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.040
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.040
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.039
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.039
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.039
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.039
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.038
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.038
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.038
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.038
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.038
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.037
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.037
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.037
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.037
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.037
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.037
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.036
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.036
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.036
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.036
|
Rat |
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.036
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.036
|
Zebrafish Mouse |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.036
|
Rat |
|
|
oogenesis
|
GO:0048477 |
2 |
0.035
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.035
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.035
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.035
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.035
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.035
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.035
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.035
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
37 |
0.035
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.035
|
|
|
|
cardiac muscle cell fate commitment
|
GO:0060923 |
4 |
0.035
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.035
|
Zebrafish |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.035
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.035
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.034
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.034
|
Rat |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.034
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.034
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.034
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.034
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.034
|
Zebrafish |
|
|
response to estrogen
|
GO:0043627 |
47 |
0.034
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.033
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.033
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.033
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.033
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
8 |
0.033
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.033
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.033
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.033
|
Zebrafish Mouse |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.033
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.032
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.032
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.032
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.032
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.032
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.031
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.031
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.031
|
Zebrafish Mouse |
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.031
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.031
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.031
|
Mouse |
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.031
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.031
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.031
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.031
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.031
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.031
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.031
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.030
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.030
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.030
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.030
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.030
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.030
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.030
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.030
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.030
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.029
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.029
|
|
|
|
response to dexamethasone
|
GO:0071548 |
1 |
0.029
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.029
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.029
|
Rat |
|
|
membrane organization
|
GO:0061024 |
292 |
0.029
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.029
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.029
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.029
|
|
|
|
respiratory system development
|
GO:0060541 |
22 |
0.029
|
|
|
|
acute inflammatory response
|
GO:0002526 |
21 |
0.028
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.028
|
|
|
|
response to interleukin 4
|
GO:0070670 |
7 |
0.028
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.028
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.028
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.028
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.028
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.028
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.028
|
Rat |
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.028
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.028
|
|
|
|
regulation of collagen metabolic process
|
GO:0010712 |
15 |
0.027
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.027
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.027
|
|
|
|
negative regulation of cellular carbohydrate metabolic process
|
GO:0010677 |
14 |
0.027
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.027
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.027
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.027
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.027
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.026
|
Mouse |
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.026
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.026
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.026
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.026
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.026
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.026
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.026
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.025
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.025
|
Zebrafish |
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.025
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.025
|
|
|
|
nephron tubule epithelial cell differentiation
|
GO:0072160 |
3 |
0.025
|
|
|
|
endocrine process
|
GO:0050886 |
25 |
0.025
|
|
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.025
|
|
