Homo sapiens

164 known processes

IL8

interleukin 8

(Aliases: LUCT,MDNCF,GCP1,NAF,GCP-1,NAP1,CXCL8,LYNAP,NAP-1,LECT,MONAP)

IL8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of acute inflammatory response GO:0002675 2 1.000
disruption by host of symbiont cells GO:0051852 2 1.000
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 18 1.000
regulation of granzyme a production GO:2000511 1 1.000
cellular response to fibroblast growth factor stimulus GO:0044344 39 1.000
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 1.000
cyclic nucleotide metabolic process GO:0009187 82 1.000
Human
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 1.000
mature natural killer cell chemotaxis GO:0035782 1 1.000
positive regulation of calcium ion transport into cytosol GO:0010524 20 0.999
Human
positive regulation of release of sequestered calcium ion into cytosol GO:0051281 16 0.999
Human
positive regulation of cd8 positive alpha beta t cell proliferation GO:2000566 1 0.999
positive regulation of t cell migration GO:2000406 13 0.999
Human
negative regulation of cd4 positive alpha beta t cell proliferation GO:2000562 1 0.999
regulation of camp metabolic process GO:0030814 52 0.998
Human
cellular response to molecule of bacterial origin GO:0071219 62 0.998
myeloid dendritic cell chemotaxis GO:0002408 3 0.998
positive regulation of killing of cells of other organism GO:0051712 4 0.998
negative regulation of lymphocyte chemotaxis GO:1901624 2 0.998
mhc class ii biosynthetic process GO:0045342 4 0.998
lymphocyte chemotaxis GO:0048247 17 0.997
Human
positive regulation of macrophage chemotaxis GO:0010759 3 0.997
cellular response to biotic stimulus GO:0071216 71 0.997
positive regulation of camp metabolic process GO:0030816 41 0.997
Human
negative regulation of cytolysis GO:0045918 3 0.996
positive regulation of homeostatic process GO:0032846 47 0.996
Human
acute inflammatory response GO:0002526 21 0.996
cellular response to interleukin 1 GO:0071347 35 0.996
positive regulation of t cell apoptotic process GO:0070234 4 0.995
regulation of chemotaxis GO:0050920 74 0.995
t cell chemotaxis GO:0010818 10 0.995
Human
cyclic nucleotide mediated signaling GO:0019935 26 0.995
Human
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.994
Human
regulation of killing of cells of other organism GO:0051709 4 0.994
regulation of camp mediated signaling GO:0043949 13 0.994
Human
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.993
negative regulation of chemokine mediated signaling pathway GO:0070100 5 0.993
granulocyte migration GO:0097530 40 0.993
neutrophil migration GO:1990266 25 0.993
g protein coupled receptor signaling pathway GO:0007186 207 0.992
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.992
regulation of neutrophil mediated killing of symbiont cell GO:0070949 1 0.992
regulation of lymphocyte migration GO:2000401 22 0.992
Human
regulation of reactive oxygen species metabolic process GO:2000377 41 0.991
cellular response to lipopolysaccharide GO:0071222 57 0.991
erk1 and erk2 cascade GO:0070371 104 0.991
regulation of leukocyte migration GO:0002685 63 0.990
Human
eosinophil activation involved in immune response GO:0002278 2 0.989
regulation of granzyme b production GO:0071661 1 0.989
negative regulation of homeostatic process GO:0032845 59 0.988
Human
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.988
chemokine mediated signaling pathway GO:0070098 16 0.987
Human
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.987
regulation of t cell chemotaxis GO:0010819 7 0.986
calcium ion transport GO:0006816 147 0.986
Human
positive regulation of behavior GO:0048520 60 0.986
response to lipopolysaccharide GO:0032496 70 0.985
neutrophil mediated cytotoxicity GO:0070942 1 0.984
regulation of viral process GO:0050792 103 0.984
positive regulation of camp mediated signaling GO:0043950 10 0.984
Human
camp metabolic process GO:0046058 61 0.984
Human
regulation of neutrophil chemotaxis GO:0090022 10 0.983
myeloid leukocyte migration GO:0097529 62 0.982
eosinophil chemotaxis GO:0048245 8 0.981
viral life cycle GO:0019058 132 0.981
regulation of ion homeostasis GO:2000021 73 0.981
Human
regulation of neutrophil mediated cytotoxicity GO:0070948 1 0.981
modification of morphology or physiology of other organism GO:0035821 43 0.981
regulation of calcium ion transport GO:0051924 79 0.981
Human
positive regulation of homotypic cell cell adhesion GO:0034112 4 0.981
negative regulation of natural killer cell chemotaxis GO:2000502 1 0.980
positive regulation of ion transport GO:0043270 87 0.979
Human
regulation of homeostatic process GO:0032844 121 0.979
Human
response to fibroblast growth factor GO:0071774 39 0.979
neutrophil mediated immunity GO:0002446 4 0.978
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.976
Human
camp mediated signaling GO:0019933 23 0.976
Human
neutrophil chemotaxis GO:0030593 24 0.975
granulocyte chemotaxis GO:0071621 37 0.975
regulation of calcium ion transport into cytosol GO:0010522 33 0.974
Human
lymphocyte migration GO:0072676 28 0.974
Human
cellular response to endogenous stimulus GO:0071495 336 0.974
positive regulation of calcium ion transport GO:0051928 51 0.973
Human
leukocyte migration GO:0050900 107 0.973
negative regulation of mhc class ii biosynthetic process GO:0045347 1 0.973
positive regulation of granzyme a production GO:2000513 1 0.973
negative regulation of lymphocyte migration GO:2000402 4 0.971
defense response GO:0006952 315 0.971
cytokine production GO:0001816 247 0.968
natural killer cell chemotaxis GO:0035747 6 0.968
regulation of ion transport GO:0043269 189 0.968
Human
response to biotic stimulus GO:0009607 276 0.968
positive regulation of response to external stimulus GO:0032103 88 0.968
regulation of smooth muscle cell proliferation GO:0048660 28 0.968
regulation of cytokine production GO:0001817 232 0.967
negative regulation of apoptotic process GO:0043066 316 0.966
regulation of defense response GO:0031347 154 0.965
cellular response to oxygen containing compound GO:1901701 276 0.965
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.964
response to molecule of bacterial origin GO:0002237 82 0.964
regulation of t cell migration GO:2000404 14 0.963
Human
negative regulation of apoptotic signaling pathway GO:2001234 97 0.962
negative regulation of alpha beta t cell proliferation GO:0046642 1 0.962
establishment of lymphocyte polarity GO:0001767 2 0.961
sequestering of metal ion GO:0051238 24 0.960
sequestering of calcium ion GO:0051208 17 0.958
response to cytokine GO:0034097 232 0.957
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.956
positive regulation of natural killer cell chemotaxis GO:2000503 5 0.955
positive regulation of cellular component movement GO:0051272 181 0.954
Human
cd8 positive alpha beta t cell activation GO:0036037 3 0.954
regulation of myeloid cell differentiation GO:0045637 81 0.951
positive regulation of lymphocyte migration GO:2000403 16 0.951
Human
negative regulation of sequestering of calcium ion GO:0051283 41 0.950
Human
viral process GO:0016032 146 0.949
cell chemotaxis GO:0060326 112 0.947
positive regulation of superoxide anion generation GO:0032930 4 0.947
cellular divalent inorganic cation homeostasis GO:0072503 128 0.946
Human
positive regulation of cytoplasmic transport GO:1903651 82 0.944
Human
modification by host of symbiont morphology or physiology GO:0051851 26 0.944
sodium ion transport GO:0006814 61 0.942
regulation of chemokine mediated signaling pathway GO:0070099 6 0.942
regulation of sequestering of calcium ion GO:0051282 41 0.941
Human
positive regulation of cell motility GO:2000147 177 0.940
Human
positive regulation of defense response GO:0031349 87 0.938
granzyme b production GO:0071613 1 0.937
apoptotic signaling pathway GO:0097190 268 0.937
regulation of apoptotic signaling pathway GO:2001233 175 0.937
cytokine mediated signaling pathway GO:0019221 109 0.936
Human
inflammatory response GO:0006954 79 0.936
positive regulation of calcidiol 1 monooxygenase activity GO:0060559 3 0.936
response to growth factor GO:0070848 205 0.935
cellular calcium ion homeostasis GO:0006874 117 0.933
Human
negative regulation of programmed cell death GO:0043069 321 0.933
positive regulation of intracellular protein transport GO:0090316 76 0.933
positive regulation of locomotion GO:0040017 186 0.932
eosinophil degranulation GO:0043308 2 0.932
negative regulation of t helper 1 cell activation GO:2000518 1 0.924
myeloid cell differentiation GO:0030099 117 0.923
cellular response to lipid GO:0071396 127 0.921
response to other organism GO:0051707 261 0.917
killing of cells in other organism involved in symbiotic interaction GO:0051883 3 0.916
positive regulation of cell migration GO:0030335 172 0.916
Human
negative regulation of cell death GO:0060548 345 0.916
regulation of inflammatory response GO:0050727 46 0.914
reactive nitrogen species metabolic process GO:2001057 3 0.914
regulation of cell motility GO:2000145 299 0.913
Human
leukocyte chemotaxis GO:0030595 76 0.913
immune system development GO:0002520 195 0.912
disruption of cells of other organism involved in symbiotic interaction GO:0051818 3 0.912
positive regulation of protein import into nucleus GO:0042307 46 0.912
cytosolic calcium ion homeostasis GO:0051480 89 0.912
Human
reactive oxygen species metabolic process GO:0072593 75 0.910
response to organonitrogen compound GO:0010243 156 0.910
regulation of natural killer cell chemotaxis GO:2000501 6 0.909
rna replication GO:0039703 9 0.909
positive regulation of potassium ion transport GO:0043268 15 0.909
positive regulation of cell proliferation GO:0008284 301 0.902
positive regulation of nucleotide metabolic process GO:0045981 230 0.900
Human
release of sequestered calcium ion into cytosol GO:0051209 41 0.900
Human
calcium ion transport into cytosol GO:0060402 48 0.898
Human
chronic inflammatory response GO:0002544 2 0.898
negative regulation of cd4 positive alpha beta t cell activation GO:2000515 1 0.896
eosinophil activation GO:0043307 3 0.894
negative regulation of bone mineralization GO:0030502 7 0.893
regulation of anatomical structure morphogenesis GO:0022603 286 0.890
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.887
divalent metal ion transport GO:0070838 152 0.884
Human
positive regulation of transport GO:0051050 336 0.884
Human
cation transport GO:0006812 331 0.884
Human
positive regulation of leukocyte migration GO:0002687 46 0.883
Human
positive regulation of cytokine production GO:0001819 167 0.881
regulation of cell migration GO:0030334 289 0.880
Human
response to fatty acid GO:0070542 13 0.878
interaction with symbiont GO:0051702 26 0.876
t cell migration GO:0072678 16 0.876
Human
calcium ion homeostasis GO:0055074 122 0.875
Human
divalent inorganic cation transport GO:0072511 158 0.875
Human
response to interleukin 1 GO:0070555 47 0.873
positive regulation of nf kappab import into nucleus GO:0042346 13 0.873
regulation of protein import into nucleus GO:0042306 78 0.873
multi organism metabolic process GO:0044033 41 0.873
response to abiotic stimulus GO:0009628 336 0.870
second messenger mediated signaling GO:0019932 78 0.869
Human
regulation of response to external stimulus GO:0032101 222 0.869
blood vessel development GO:0001568 172 0.864
defense response to other organism GO:0098542 129 0.863
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.863
taxis GO:0042330 157 0.863
response to oxygen containing compound GO:1901700 369 0.862
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.859
regulation of c c chemokine binding GO:2001263 1 0.855
positive regulation of immune system process GO:0002684 283 0.851
Human
response to organic cyclic compound GO:0014070 204 0.850
positive regulation of chemotaxis GO:0050921 57 0.850
response to alcohol GO:0097305 64 0.849
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.846
regulation of erk1 and erk2 cascade GO:0070372 99 0.845
vasculature development GO:0001944 181 0.843
regulation of metal ion transport GO:0010959 120 0.842
Human
chemical homeostasis GO:0048878 306 0.842
Human
cell killing GO:0001906 34 0.840
response to external biotic stimulus GO:0043207 261 0.840
response to gamma radiation GO:0010332 14 0.837
potassium ion transport GO:0006813 62 0.837
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.836
regulation of angiogenesis GO:0045765 92 0.835
divalent inorganic cation homeostasis GO:0072507 136 0.834
Human
reactive oxygen species biosynthetic process GO:1903409 4 0.833
neutrophil mediated killing of symbiont cell GO:0070943 1 0.833
acute phase response GO:0006953 5 0.830
negative regulation of myeloid cell differentiation GO:0045638 42 0.829
metal ion transport GO:0030001 272 0.828
Human
negative regulation of c c chemokine binding GO:2001264 1 0.828
response to lipid GO:0033993 206 0.827
negative regulation of cell proliferation GO:0008285 228 0.824
positive regulation of smooth muscle cell proliferation GO:0048661 14 0.823
regulation of monocyte chemotaxis GO:0090025 11 0.822
defense response to fungus GO:0050832 4 0.819
positive regulation of myosin light chain kinase activity GO:0035505 1 0.818
positive regulation of cd8 positive alpha beta t cell activation GO:2001187 1 0.816
negative regulation of developmental process GO:0051093 247 0.815
establishment of t cell polarity GO:0001768 2 0.814
positive regulation of intracellular transport GO:0032388 104 0.814
Human
induction of positive chemotaxis GO:0050930 8 0.814
regulation of macrophage chemotaxis GO:0010758 4 0.810
positive regulation of granulocyte chemotaxis GO:0071624 9 0.809
negative regulation of multicellular organismal metabolic process GO:0044252 3 0.808
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.803
positive regulation of developmental process GO:0051094 314 0.802
multi organism cellular process GO:0044764 156 0.802
regulation of nucleotide metabolic process GO:0006140 269 0.800
Human
t helper 1 cell activation GO:0035711 1 0.799
regulation of viral genome replication GO:0045069 48 0.799
muscle cell proliferation GO:0033002 35 0.798
response to fungus GO:0009620 4 0.797
hemopoiesis GO:0030097 180 0.795
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.792
Human
secretion GO:0046903 254 0.788
cellular response to growth factor stimulus GO:0071363 197 0.787
macrophage chemotaxis GO:0048246 10 0.784
chemotaxis GO:0006935 157 0.782
metal ion homeostasis GO:0055065 169 0.781
Human
glial cell migration GO:0008347 4 0.781
regulation of behavior GO:0050795 82 0.781
granzyme a production GO:0035746 1 0.780
biomineral tissue development GO:0031214 39 0.779
regulation of cellular amino acid metabolic process GO:0006521 6 0.775
regulation of vasculature development GO:1901342 97 0.774
nucleocytoplasmic transport GO:0006913 176 0.774
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.773
cation homeostasis GO:0055080 189 0.773
Human
negative regulation of multicellular organismal process GO:0051241 317 0.769
regulation of cellular component movement GO:0051270 334 0.769
Human
regulation of intracellular transport GO:0032386 195 0.767
Human
regulation of cell adhesion GO:0030155 166 0.767
killing by host of symbiont cells GO:0051873 2 0.764
cellular chemical homeostasis GO:0055082 180 0.760
Human
response to glucocorticoid GO:0051384 13 0.759
positive regulation of myeloid cell differentiation GO:0045639 39 0.759
regulation of release of sequestered calcium ion into cytosol GO:0051279 27 0.758
Human
positive regulation of alpha beta t cell proliferation GO:0046641 5 0.757
regulation of leukocyte chemotaxis GO:0002688 46 0.755
regulation of nf kappab import into nucleus GO:0042345 22 0.755
regulation of neutrophil migration GO:1902622 10 0.744
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 38 0.742
biological adhesion GO:0022610 331 0.742
negative regulation of cell differentiation GO:0045596 171 0.740
wound healing GO:0042060 115 0.737
cellular cation homeostasis GO:0030003 163 0.737
Human
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.737
response to hormone GO:0009725 175 0.733
response to reactive oxygen species GO:0000302 61 0.728
single organism cellular localization GO:1902580 332 0.726
ion homeostasis GO:0050801 230 0.725
Human
response to endoplasmic reticulum stress GO:0034976 49 0.725
leukocyte mediated cytotoxicity GO:0001909 27 0.724
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.721
response to steroid hormone GO:0048545 80 0.721
response to estradiol GO:0032355 23 0.720
hematopoietic or lymphoid organ development GO:0048534 186 0.718
amide transport GO:0042886 76 0.717
regulation of leukocyte mediated immunity GO:0002703 38 0.716
maintenance of location GO:0051235 112 0.716
response to wounding GO:0009611 168 0.715
positive regulation of leukocyte mediated immunity GO:0002705 24 0.714
response to bacterium GO:0009617 144 0.712
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.709
regulation of protein localization GO:0032880 296 0.707
interspecies interaction between organisms GO:0044419 156 0.705
i kappab kinase nf kappab signaling GO:0007249 166 0.699
regulation of cell differentiation GO:0045595 393 0.696
viral genome replication GO:0019079 50 0.694
response to nitrogen compound GO:1901698 184 0.690
regulation of cell cell adhesion mediated by integrin GO:0033632 6 0.683
positive regulation of phosphorylation GO:0042327 394 0.681
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.679
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.679
positive regulation of protein localization to nucleus GO:1900182 48 0.676
leukocyte mediated immunity GO:0002443 59 0.674
positive regulation of jak stat cascade GO:0046427 35 0.674
cellular response to tumor necrosis factor GO:0071356 63 0.673
positive regulation of mapk cascade GO:0043410 190 0.672
mapk cascade GO:0000165 288 0.666
negative regulation of collagen biosynthetic process GO:0032966 2 0.660
single organism nuclear import GO:1902593 104 0.658
regulation of t helper 1 cell activation GO:2000517 1 0.654
regulation of mhc class ii biosynthetic process GO:0045346 4 0.653
nitrogen compound transport GO:0071705 191 0.649
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.648
positive regulation of keratinocyte migration GO:0051549 4 0.648
regulation of lymphocyte chemotaxis GO:1901623 12 0.648
positive regulation of granzyme b production GO:0071663 1 0.647
regulation of heterotypic cell cell adhesion GO:0034114 14 0.645
cellular homeostasis GO:0019725 196 0.645
Human
positive regulation of neutrophil chemotaxis GO:0090023 7 0.642
positive regulation of epithelial cell proliferation GO:0050679 65 0.635
peptide transport GO:0015833 74 0.634
regulation of leukocyte proliferation GO:0070663 67 0.630
nervous system development GO:0007399 293 0.629
single stranded viral rna replication via double stranded dna intermediate GO:0039692 9 0.625
positive regulation of t cell proliferation GO:0042102 33 0.624
regulation of cellular ketone metabolic process GO:0010565 50 0.624
positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 0.623
cytosolic calcium ion transport GO:0060401 48 0.623
Human
chemokine metabolic process GO:0050755 4 0.618
regulation of macrophage differentiation GO:0045649 9 0.617
regulation of leukocyte differentiation GO:1902105 61 0.615
cellular ion homeostasis GO:0006873 168 0.614
Human
cardiovascular system development GO:0072358 262 0.610
digestive tract development GO:0048565 75 0.610
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.610
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.609
regulation of cytoplasmic transport GO:1903649 149 0.608
Human
extrinsic apoptotic signaling pathway GO:0097191 119 0.608
leukocyte apoptotic process GO:0071887 31 0.607
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.605
Human
response to corticosteroid GO:0031960 15 0.605
intracellular protein transport GO:0006886 270 0.603
cellular metal ion homeostasis GO:0006875 146 0.594
Human
myeloid leukocyte mediated immunity GO:0002444 10 0.593
regulation of protein targeting GO:1903533 91 0.593
blood coagulation GO:0007596 76 0.592
negative regulation of lymphocyte apoptotic process GO:0070229 8 0.591
positive regulation of leukocyte proliferation GO:0070665 48 0.589
negative regulation of collagen metabolic process GO:0010713 3 0.588
viral rna genome replication GO:0039694 9 0.588
negative regulation of alpha beta t cell activation GO:0046636 3 0.579
positive regulation of monocyte chemotaxis GO:0090026 10 0.569
cellular lipid metabolic process GO:0044255 303 0.567
cellular response to organic cyclic compound GO:0071407 127 0.564
embryonic digestive tract development GO:0048566 10 0.563
regulation of peptidase activity GO:0052547 180 0.561
cytoplasmic transport GO:0016482 379 0.559
Human
regulation of immune effector process GO:0002697 91 0.555
regulation of locomotion GO:0040012 329 0.553
negative regulation of t cell cytokine production GO:0002725 4 0.553
regulation of response to wounding GO:1903034 101 0.553
regulation of leukocyte mediated cytotoxicity GO:0001910 19 0.549
positive chemotaxis GO:0050918 33 0.548
positive regulation of cell cell adhesion GO:0022409 22 0.548
response to ionizing radiation GO:0010212 65 0.542
response to tumor necrosis factor GO:0034612 76 0.541
positive regulation of nitric oxide biosynthetic process GO:0045429 13 0.540
monocyte chemotaxis GO:0002548 20 0.538
regulation of cell cell adhesion GO:0022407 57 0.533
cell activation GO:0001775 213 0.532
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.531
disruption of cells of other organism GO:0044364 7 0.529
positive regulation of cell differentiation GO:0045597 211 0.528
regulation of single stranded viral rna replication via double stranded dna intermediate GO:0045091 8 0.527
regulation of myeloid leukocyte differentiation GO:0002761 39 0.526
regulation of macrophage derived foam cell differentiation GO:0010743 14 0.522
tube development GO:0035295 125 0.518
immune effector process GO:0002252 159 0.514
regulation of purine nucleotide metabolic process GO:1900542 264 0.509
Human
signal transduction in absence of ligand GO:0038034 22 0.508
leukocyte differentiation GO:0002521 98 0.505
blood vessel morphogenesis GO:0048514 162 0.505
negative regulation of biomineral tissue development GO:0070168 8 0.498
regulation of immune response GO:0050776 201 0.488
cellular response to cytokine stimulus GO:0071345 181 0.483
nuclear transport GO:0051169 179 0.479
nf kappab import into nucleus GO:0042348 22 0.478
response to radiation GO:0009314 151 0.476
peptide hormone secretion GO:0030072 50 0.474
superoxide metabolic process GO:0006801 20 0.473
intrinsic apoptotic signaling pathway GO:0097193 127 0.470
regulation of cell cycle GO:0051726 393 0.469
signal transduction by phosphorylation GO:0023014 297 0.465
interleukin 6 production GO:0032635 37 0.464
negative regulation of blood vessel morphogenesis GO:2000181 41 0.464
regulation of hematopoietic progenitor cell differentiation GO:1901532 24 0.461
regulation of transcription factor import into nucleus GO:0042990 39 0.459
regulation of hematopoietic stem cell proliferation GO:1902033 1 0.457
regulation of epithelial cell proliferation GO:0050678 113 0.457
monocyte aggregation GO:0070487 4 0.454
circulatory system development GO:0072359 262 0.452
regulation of multi organism process GO:0043900 157 0.444
establishment of protein localization to organelle GO:0072594 172 0.441
positive regulation of myeloid leukocyte mediated immunity GO:0002888 1 0.440
regulation of mononuclear cell proliferation GO:0032944 65 0.439
cell adhesion GO:0007155 325 0.438
receptor internalization GO:0031623 43 0.437
cytolysis GO:0019835 8 0.435
peptidyl tyrosine phosphorylation GO:0018108 170 0.433
negative regulation of megakaryocyte differentiation GO:0045653 16 0.432
vesicle mediated transport GO:0016192 371 0.429
regulation of acute inflammatory response GO:0002673 13 0.426
cellular amino acid metabolic process GO:0006520 116 0.424
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.423
ribonucleotide catabolic process GO:0009261 405 0.421
superoxide anion generation GO:0042554 11 0.421
positive regulation of lymphocyte proliferation GO:0050671 46 0.420
positive regulation of heterotypic cell cell adhesion GO:0034116 8 0.419
positive regulation of stress activated mapk cascade GO:0032874 60 0.416
regulation of sensory perception of pain GO:0051930 3 0.415
regulation of granulocyte chemotaxis GO:0071622 16 0.411
cellular amine metabolic process GO:0044106 41 0.410
regulation of interleukin 8 production GO:0032677 49 0.406
ion transmembrane transport GO:0034220 338 0.396
regulation of positive chemotaxis GO:0050926 14 0.395
regulation of blood vessel size GO:0050880 18 0.392
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.389
regulation of chemokine biosynthetic process GO:0045073 4 0.388
regulation of mapk cascade GO:0043408 262 0.382
negative regulation of immune system process GO:0002683 136 0.381
behavior GO:0007610 112 0.378
receptor metabolic process GO:0043112 81 0.373
regulation of cell killing GO:0031341 22 0.372
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.371
regulation of protein localization to nucleus GO:1900180 85 0.366
cell cycle arrest GO:0007050 71 0.366
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.359
chemokine biosynthetic process GO:0042033 4 0.356
positive regulation of apoptotic process GO:0043065 246 0.356
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.351
anatomical structure formation involved in morphogenesis GO:0048646 284 0.344
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.343
regulation of nucleocytoplasmic transport GO:0046822 98 0.342
hormone transport GO:0009914 68 0.338
regulation of establishment of protein localization GO:0070201 242 0.336
regulation of hormone secretion GO:0046883 57 0.332
positive regulation of sodium ion transport GO:0010765 14 0.330
response to inorganic substance GO:0010035 127 0.327
glial cell apoptotic process GO:0034349 7 0.324
regulation of interleukin 1 mediated signaling pathway GO:2000659 3 0.323
jak stat cascade GO:0007259 46 0.323
regulation of potassium ion transport GO:0043266 24 0.321
positive regulation of protein transport GO:0051222 135 0.319
positive regulation of jnk cascade GO:0046330 52 0.317
negative regulation of angiogenesis GO:0016525 39 0.314
cd4 positive alpha beta t cell activation GO:0035710 6 0.310
positive regulation of leukocyte chemotaxis GO:0002690 38 0.308
killing of cells of other organism GO:0031640 7 0.305
positive regulation of mononuclear cell proliferation GO:0032946 47 0.303
positive regulation of t cell chemotaxis GO:0010820 7 0.301
hematopoietic stem cell proliferation GO:0071425 6 0.301
regulation of sodium ion transport GO:0002028 24 0.301
leukocyte aggregation GO:0070486 8 0.298
production of molecular mediator of immune response GO:0002440 37 0.297
digestive system development GO:0055123 75 0.293
neutrophil apoptotic process GO:0001781 2 0.289
platelet activation GO:0030168 44 0.285
regulation of leukocyte activation GO:0002694 115 0.285
bone mineralization GO:0030282 34 0.285
sarcoplasmic reticulum calcium ion transport GO:0070296 13 0.279
neuron death GO:0070997 65 0.279
positive regulation of nucleotide catabolic process GO:0030813 185 0.279
cytokine biosynthetic process GO:0042089 37 0.278
positive regulation of programmed cell death GO:0043068 249 0.278
amine metabolic process GO:0009308 44 0.277
regulation of dna metabolic process GO:0051052 153 0.276
positive regulation of cell death GO:0010942 263 0.275
neuron apoptotic process GO:0051402 39 0.275
regulation of cd8 positive alpha beta t cell activation GO:2001185 2 0.267
positive regulation of catabolic process GO:0009896 310 0.267
positive regulation of synaptic transmission GO:0050806 4 0.265
megakaryocyte differentiation GO:0030219 25 0.263
hematopoietic progenitor cell differentiation GO:0002244 38 0.261
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.260
cellular response to organonitrogen compound GO:0071417 124 0.259
regulation of system process GO:0044057 101 0.259
kinin cascade GO:0002254 1 0.259
positive regulation of vitamin d biosynthetic process GO:0060557 3 0.258
system process GO:0003008 349 0.254
positive regulation of inflammatory response GO:0050729 10 0.254
myeloid leukocyte differentiation GO:0002573 60 0.253
female gamete generation GO:0007292 2 0.250
cellular response to lipoteichoic acid GO:0071223 3 0.249
angiogenesis GO:0001525 147 0.249
response to estrogen GO:0043627 47 0.247
response to prostaglandin e GO:0034695 6 0.245
regulation of stem cell proliferation GO:0072091 15 0.244
positive regulation of neutrophil migration GO:1902624 7 0.243
negative regulation of t cell proliferation GO:0042130 8 0.243
activation of phospholipase d activity GO:0031584 3 0.242

IL8 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.590
cancer DOID:162 167 0.263