Homo sapiens

0 known processes

INO80B

INO80 complex subunit B

(Aliases: hIes2,HMGA1L4,ZNHIT4,PAP-1BP,IES2,PAPA-1,HMGIYL4)

INO80B biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of myoblast differentiation GO:0045663 6 0.443
negative regulation of insulin like growth factor receptor signaling pathway GO:0043569 4 0.437
regulation of cellular amino acid metabolic process GO:0006521 6 0.271
cellular response to camp GO:0071320 21 0.247
amine metabolic process GO:0009308 44 0.181
response to lithium ion GO:0010226 2 0.154
regulation of cellular ketone metabolic process GO:0010565 50 0.139
regulation of striated muscle tissue development GO:0016202 26 0.138
cellular amino acid metabolic process GO:0006520 116 0.138
cellular ketone metabolic process GO:0042180 80 0.129
negative regulation of cell migration GO:0030336 102 0.127
myoblast differentiation GO:0045445 21 0.127
regulation of cellular amine metabolic process GO:0033238 11 0.126
muscle cell migration GO:0014812 19 0.122
negative regulation of cellular protein metabolic process GO:0032269 353 0.119
translation GO:0006412 132 0.112
response to oxygen containing compound GO:1901700 369 0.110
glycerolipid biosynthetic process GO:0045017 51 0.107
anatomical structure formation involved in morphogenesis GO:0048646 284 0.107
chromatin organization GO:0006325 351 0.106
regulation of lipid metabolic process GO:0019216 96 0.104
positive regulation of programmed cell death GO:0043068 249 0.101
positive regulation of leukocyte proliferation GO:0070665 48 0.101
regulation of dna replication GO:0006275 68 0.100
regulation of cell motility GO:2000145 299 0.096
chromatin modification GO:0016568 298 0.096
negative regulation of dna metabolic process GO:0051053 57 0.093
negative regulation of smooth muscle cell migration GO:0014912 7 0.093
cellular response to endogenous stimulus GO:0071495 336 0.090
response to alcohol GO:0097305 64 0.090
positive regulation of cellular amine metabolic process GO:0033240 7 0.090
lipid metabolic process GO:0006629 381 0.089
plasma membrane fusion GO:0045026 2 0.089
regulation of locomotion GO:0040012 329 0.088
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.085
cellular amine metabolic process GO:0044106 41 0.084
cellular lipid metabolic process GO:0044255 303 0.083
negative regulation of protein metabolic process GO:0051248 391 0.081
activation of mapk activity GO:0000187 45 0.081
cellular response to oxygen containing compound GO:1901701 276 0.080
negative regulation of protein phosphorylation GO:0001933 140 0.079
response to organic cyclic compound GO:0014070 204 0.078
negative regulation of phosphorylation GO:0042326 174 0.077
negative regulation of phosphate metabolic process GO:0045936 267 0.077
regulation of cellular component movement GO:0051270 334 0.076
positive regulation of protein kinase activity GO:0045860 190 0.074
negative regulation of dna replication GO:0008156 29 0.074
response to organonitrogen compound GO:0010243 156 0.073
negative regulation of developmental process GO:0051093 247 0.072
regulation of muscle cell differentiation GO:0051147 31 0.064
negative regulation of multicellular organismal process GO:0051241 317 0.064
positive regulation of transferase activity GO:0051347 227 0.062
response to lipid GO:0033993 206 0.062
regulation of protein serine threonine kinase activity GO:0071900 179 0.062
positive regulation of apoptotic process GO:0043065 246 0.061
single organism membrane fusion GO:0044801 37 0.061
positive regulation of phosphorylation GO:0042327 394 0.061
growth GO:0040007 202 0.060
positive regulation of muscle cell differentiation GO:0051149 15 0.058
positive regulation of cell proliferation GO:0008284 301 0.058
regulation of kinase activity GO:0043549 314 0.058
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.057
regulation of protein kinase activity GO:0045859 289 0.057
cellular response to organic cyclic compound GO:0071407 127 0.057
response to hormone GO:0009725 175 0.056
response to camp GO:0051591 25 0.056
glycerolipid metabolic process GO:0046486 107 0.056
activation of protein kinase activity GO:0032147 90 0.055
peptidyl tyrosine modification GO:0018212 170 0.055
muscle cell proliferation GO:0033002 35 0.055
regulation of cell development GO:0060284 161 0.054
negative regulation of smooth muscle cell proliferation GO:0048662 14 0.054
regulation of growth GO:0040008 165 0.053
skeletal muscle fiber development GO:0048741 12 0.052
regulation of striated muscle cell differentiation GO:0051153 25 0.051
response to inorganic substance GO:0010035 127 0.051
negative regulation of growth GO:0045926 97 0.051
positive regulation of kinase activity GO:0033674 204 0.050
negative regulation of cell proliferation GO:0008285 228 0.049
regulation of dna metabolic process GO:0051052 153 0.049
positive regulation of cell death GO:0010942 263 0.048
positive regulation of t cell proliferation GO:0042102 33 0.048
negative regulation of cell motility GO:2000146 104 0.047
regulation of smooth muscle cell proliferation GO:0048660 28 0.047
fusion of sperm to egg plasma membrane GO:0007342 2 0.046
t cell activation GO:0042110 99 0.046
regulation of translation GO:0006417 89 0.046
regulation of muscle organ development GO:0048634 27 0.045
response to organophosphorus GO:0046683 41 0.045
regulation of cell activation GO:0050865 125 0.044
axonemal dynein complex assembly GO:0070286 11 0.044
positive regulation of cell differentiation GO:0045597 211 0.044
negative regulation of cellular component movement GO:0051271 106 0.044
leukocyte proliferation GO:0070661 74 0.043
smooth muscle cell proliferation GO:0048659 28 0.043
response to estradiol GO:0032355 23 0.043
regulation of muscle tissue development GO:1901861 26 0.042
blood vessel morphogenesis GO:0048514 162 0.042
heart development GO:0007507 95 0.042
striated muscle tissue development GO:0014706 59 0.040
mononuclear cell proliferation GO:0032943 71 0.040
regulation of leukocyte activation GO:0002694 115 0.040
insulin like growth factor receptor signaling pathway GO:0048009 13 0.039
dna replication GO:0006260 116 0.039
smooth muscle cell migration GO:0014909 18 0.039
regulation of t cell activation GO:0050863 77 0.038
lymphocyte activation GO:0046649 133 0.038
regulation of insulin like growth factor receptor signaling pathway GO:0043567 8 0.038
circulatory system development GO:0072359 262 0.038
response to purine containing compound GO:0014074 40 0.037
positive regulation of developmental process GO:0051094 314 0.037
enzyme linked receptor protein signaling pathway GO:0007167 303 0.037
positive regulation of lymphocyte proliferation GO:0050671 46 0.037
activated t cell proliferation GO:0050798 13 0.036
post embryonic development GO:0009791 2 0.036
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.036
regulation of lymphocyte activation GO:0051249 103 0.035
cell activation GO:0001775 213 0.035
negative regulation of phosphorus metabolic process GO:0010563 267 0.034
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.034
cellular response to hormone stimulus GO:0032870 125 0.034
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.034
response to estrogen GO:0043627 47 0.034
histone exchange GO:0043486 3 0.034
regulation of mononuclear cell proliferation GO:0032944 65 0.034
response to nitrogen compound GO:1901698 184 0.034
cellular response to nitrogen compound GO:1901699 144 0.034
histone h4 acetylation GO:0043967 47 0.034
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.033
membrane organization GO:0061024 292 0.033
positive regulation of leukocyte activation GO:0002696 80 0.033
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.032
regulation of cell differentiation GO:0045595 393 0.032
organophosphate catabolic process GO:0046434 430 0.032
leukocyte activation GO:0045321 164 0.032
determination of adult lifespan GO:0008340 2 0.031
positive regulation of t cell activation GO:0050870 54 0.031
response to retinoic acid GO:0032526 33 0.031
cardiovascular system development GO:0072358 262 0.031
positive regulation of cell activation GO:0050867 81 0.030
regulation of myotube differentiation GO:0010830 18 0.030
protein dna complex subunit organization GO:0071824 80 0.030
cellular response to organonitrogen compound GO:0071417 124 0.029
regulation of transferase activity GO:0051338 355 0.029
regulation of leukocyte proliferation GO:0070663 67 0.028
positive regulation of map kinase activity GO:0043406 80 0.028
regulation of lymphocyte proliferation GO:0050670 64 0.028
positive regulation of cell cycle GO:0045787 140 0.028
regulation of map kinase activity GO:0043405 108 0.027
positive regulation of lipid metabolic process GO:0045834 50 0.027
phospholipid metabolic process GO:0006644 99 0.027
positive regulation of mononuclear cell proliferation GO:0032946 47 0.027
regulation of cell migration GO:0030334 289 0.027
negative regulation of protein modification process GO:0031400 200 0.026
response to metal ion GO:0010038 84 0.026
regulation of lipid kinase activity GO:0043550 19 0.026
positive regulation of activated t cell proliferation GO:0042104 11 0.026
response to nutrient GO:0007584 20 0.026
lipid biosynthetic process GO:0008610 177 0.025
signal transduction by phosphorylation GO:0023014 297 0.025
blood vessel development GO:0001568 172 0.025
chromatin remodeling GO:0006338 55 0.025
multicellular organismal aging GO:0010259 3 0.025
apoptotic signaling pathway GO:0097190 268 0.025
lymphocyte proliferation GO:0046651 70 0.025
single organism membrane organization GO:0044802 268 0.024
regulation of cell growth GO:0001558 135 0.024
skeletal muscle tissue development GO:0007519 24 0.024
response to other organism GO:0051707 261 0.024
glycerophospholipid biosynthetic process GO:0046474 40 0.024
purine nucleoside monophosphate metabolic process GO:0009126 186 0.024
transmembrane transport GO:0055085 399 0.024
histone modification GO:0016570 251 0.024
histone acetylation GO:0016573 93 0.023
chromosome segregation GO:0007059 114 0.023
response to light stimulus GO:0009416 87 0.023
reproductive process GO:0022414 106 0.023
response to nutrient levels GO:0031667 81 0.023
response to abiotic stimulus GO:0009628 336 0.023
nucleoside monophosphate metabolic process GO:0009123 191 0.023
single organism cellular localization GO:1902580 332 0.023
positive regulation of mapk cascade GO:0043410 190 0.023
negative regulation of locomotion GO:0040013 118 0.022
developmental growth GO:0048589 48 0.021
response to acid chemical GO:0001101 66 0.021
posttranscriptional regulation of gene expression GO:0010608 213 0.021
vasculature development GO:0001944 181 0.021
response to mechanical stimulus GO:0009612 51 0.021
negative regulation of translation GO:0017148 37 0.021
regulation of mapk cascade GO:0043408 262 0.020
atp metabolic process GO:0046034 176 0.020
phosphatidylinositol metabolic process GO:0046488 53 0.019
regulation of skeletal muscle fiber development GO:0048742 12 0.019
purine nucleoside triphosphate catabolic process GO:0009146 392 0.019
cilium assembly GO:0042384 63 0.018
phospholipid biosynthetic process GO:0008654 44 0.018
biological adhesion GO:0022610 331 0.018
protein localization to organelle GO:0033365 280 0.018
organic acid biosynthetic process GO:0016053 97 0.018
cellular response to lipid GO:0071396 127 0.018
microtubule cytoskeleton organization GO:0000226 176 0.018
nucleosome organization GO:0034728 66 0.018
positive regulation of transport GO:0051050 336 0.018
positive regulation of cell cycle process GO:0090068 106 0.017
microtubule based process GO:0007017 210 0.017
purine containing compound catabolic process GO:0072523 411 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
response to external biotic stimulus GO:0043207 261 0.017
muscle structure development GO:0061061 98 0.017
regulation of activated t cell proliferation GO:0046006 12 0.017
positive regulation of immune system process GO:0002684 283 0.017
endosomal transport GO:0016197 129 0.016
chromatin assembly GO:0031497 61 0.016
peptidyl tyrosine phosphorylation GO:0018108 170 0.016
nucleoside catabolic process GO:0009164 408 0.016
positive regulation of dna metabolic process GO:0051054 73 0.016
positive regulation of organelle organization GO:0010638 195 0.016
segmentation GO:0035282 4 0.016
skeletal muscle organ development GO:0060538 26 0.016
cilium organization GO:0044782 68 0.016
negative regulation of developmental growth GO:0048640 10 0.016
vesicle mediated transport GO:0016192 371 0.016
regulation of cellular component biogenesis GO:0044087 281 0.015
cellular response to radiation GO:0071478 65 0.015
dna geometric change GO:0032392 32 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
positive regulation of cytokine production GO:0001819 167 0.015
nucleotide catabolic process GO:0009166 408 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
protein deubiquitination GO:0016579 79 0.015
response to uv GO:0009411 73 0.015
central nervous system development GO:0007417 123 0.015
cell fate determination GO:0001709 3 0.015
locomotory behavior GO:0007626 1 0.014
small molecule biosynthetic process GO:0044283 157 0.014
protein modification by small protein removal GO:0070646 92 0.014
myotube cell development GO:0014904 14 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
neuromuscular junction development GO:0007528 3 0.014
head development GO:0060322 108 0.014
myotube differentiation GO:0014902 22 0.014
intracellular protein transport GO:0006886 270 0.014
ribonucleoside catabolic process GO:0042454 406 0.014
anterior posterior axis specification GO:0009948 2 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
purine nucleoside monophosphate catabolic process GO:0009128 158 0.014
regulation of proteolysis GO:0030162 293 0.014
rna processing GO:0006396 255 0.014
protein catabolic process GO:0030163 325 0.014
spermatid differentiation GO:0048515 4 0.013
spermatid development GO:0007286 4 0.013
purine nucleoside catabolic process GO:0006152 398 0.013
negative regulation of catalytic activity GO:0043086 335 0.013
cellular protein catabolic process GO:0044257 261 0.013
oogenesis GO:0048477 2 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
cell development GO:0048468 328 0.013
peptidyl lysine modification GO:0018205 144 0.013
cell adhesion GO:0007155 325 0.013
regulation of skeletal muscle tissue development GO:0048641 15 0.013
internal peptidyl lysine acetylation GO:0018393 97 0.013
double strand break repair via homologous recombination GO:0000724 50 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.012
cell projection organization GO:0030030 252 0.012
response to corticosteroid GO:0031960 15 0.012
ribonucleoside triphosphate catabolic process GO:0009203 391 0.012
mapk cascade GO:0000165 288 0.012
cellular carbohydrate metabolic process GO:0044262 84 0.012
muscle organ development GO:0007517 56 0.012
phosphatidylinositol biosynthetic process GO:0006661 25 0.012
sister chromatid segregation GO:0000819 54 0.012
regulation of cytokine production GO:0001817 232 0.012
rhythmic behavior GO:0007622 2 0.012
cytoplasmic transport GO:0016482 379 0.012
positive regulation of cell migration GO:0030335 172 0.012
mating GO:0007618 1 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
organelle assembly GO:0070925 176 0.012
meiotic chromosome segregation GO:0045132 4 0.012
positive regulation of locomotion GO:0040017 186 0.012
female gamete generation GO:0007292 2 0.012
brain development GO:0007420 97 0.012
nucleoside triphosphate metabolic process GO:0009141 422 0.012
glycosyl compound catabolic process GO:1901658 413 0.012
protein import GO:0017038 130 0.012
response to steroid hormone GO:0048545 80 0.012
covalent chromatin modification GO:0016569 254 0.012
regulation of establishment of protein localization GO:0070201 242 0.011
nuclear division GO:0000280 128 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
regulation of cell cycle GO:0051726 393 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
purine ribonucleoside catabolic process GO:0046130 398 0.011
multi organism reproductive process GO:0044703 54 0.011
cellular macromolecule catabolic process GO:0044265 380 0.011
primary neural tube formation GO:0014020 3 0.011
retrograde transport endosome to golgi GO:0042147 45 0.011
metencephalon development GO:0022037 2 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
tripartite regional subdivision GO:0007351 2 0.011
circadian behavior GO:0048512 2 0.011
regulation of protein transport GO:0051223 213 0.011
cellular protein complex assembly GO:0043623 188 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
regulation of protein maturation GO:1903317 150 0.011
response to wounding GO:0009611 168 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
regulation of response to external stimulus GO:0032101 222 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
associative learning GO:0008306 1 0.010
tube closure GO:0060606 3 0.010
innate immune response GO:0045087 178 0.010
purine ribonucleoside metabolic process GO:0046128 437 0.010
defense response GO:0006952 315 0.010
regulation of cell cycle process GO:0010564 266 0.010
regeneration GO:0031099 4 0.010
reactive nitrogen species metabolic process GO:2001057 3 0.010
immune system development GO:0002520 195 0.010
response to biotic stimulus GO:0009607 276 0.010
positive regulation of cellular catabolic process GO:0031331 284 0.010
membrane lipid metabolic process GO:0006643 53 0.010
sphingolipid metabolic process GO:0006665 38 0.010
reactive oxygen species biosynthetic process GO:1903409 4 0.010
endocytosis GO:0006897 159 0.010
mitotic cell cycle process GO:1903047 286 0.010
cell growth GO:0016049 160 0.010
organ formation GO:0048645 3 0.010
mitochondrion organization GO:0007005 156 0.010

INO80B disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.138
primary immunodeficiency disease DOID:612 36 0.090
hematopoietic system disease DOID:74 100 0.087
blood protein disease DOID:620 16 0.081
agammaglobulinemia DOID:2583 16 0.081
b cell deficiency DOID:2115 17 0.081
common variable immunodeficiency DOID:12177 10 0.023
central nervous system disease DOID:331 186 0.015
nervous system disease DOID:863 431 0.015
disease of metabolism DOID:0014667 295 0.013
disease of cellular proliferation DOID:14566 174 0.013
bone disease DOID:0080001 88 0.012
musculoskeletal system disease DOID:17 223 0.012
connective tissue disease DOID:65 109 0.012
brain disease DOID:936 73 0.011
sensory system disease DOID:0050155 203 0.011
neurodegenerative disease DOID:1289 102 0.011