Homo sapiens

0 known processes

IPO11

importin 11

(Aliases: RanBP11)

IPO11 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of phosphorylation GO:0042327 394 0.184
glycosyl compound catabolic process GO:1901658 413 0.126
nucleoside catabolic process GO:0009164 408 0.124
organophosphate catabolic process GO:0046434 430 0.123
positive regulation of mapk cascade GO:0043410 190 0.119
positive regulation of nucleotide metabolic process GO:0045981 230 0.110
mapk cascade GO:0000165 288 0.109
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.107
cellular lipid metabolic process GO:0044255 303 0.104
regulation of mapk cascade GO:0043408 262 0.101
positive regulation of nucleotide catabolic process GO:0030813 185 0.098
purine ribonucleotide catabolic process GO:0009154 404 0.097
purine containing compound catabolic process GO:0072523 411 0.097
signal transduction by phosphorylation GO:0023014 297 0.096
purine ribonucleoside catabolic process GO:0046130 398 0.095
regulation of gtp catabolic process GO:0033124 180 0.092
nucleoside triphosphate catabolic process GO:0009143 394 0.090
cellular amine metabolic process GO:0044106 41 0.090
ribonucleoside triphosphate metabolic process GO:0009199 412 0.088
purine nucleoside triphosphate metabolic process GO:0009144 412 0.088
amine metabolic process GO:0009308 44 0.087
regulation of purine nucleotide catabolic process GO:0033121 205 0.085
nucleoside triphosphate metabolic process GO:0009141 422 0.084
positive regulation of gtp catabolic process GO:0033126 166 0.081
response to cytokine GO:0034097 232 0.078
cellular amino acid metabolic process GO:0006520 116 0.077
positive regulation of jnk cascade GO:0046330 52 0.077
cation transport GO:0006812 331 0.075
guanosine containing compound catabolic process GO:1901069 239 0.075
purine nucleoside catabolic process GO:0006152 398 0.074
cellular ion homeostasis GO:0006873 168 0.074
positive regulation of cellular amine metabolic process GO:0033240 7 0.073
regulation of nucleotide metabolic process GO:0006140 269 0.073
gtp catabolic process GO:0006184 237 0.073
glycerolipid metabolic process GO:0046486 107 0.072
purine nucleotide catabolic process GO:0006195 405 0.071
purine ribonucleoside metabolic process GO:0046128 437 0.071
multicellular organismal aging GO:0010259 3 0.071
regulation of cellular ketone metabolic process GO:0010565 50 0.069
positive regulation of gtpase activity GO:0043547 166 0.069
cellular response to endogenous stimulus GO:0071495 336 0.068
cellular chemical homeostasis GO:0055082 180 0.067
lipid metabolic process GO:0006629 381 0.066
ribonucleotide catabolic process GO:0009261 405 0.066
regulation of nucleoside metabolic process GO:0009118 209 0.065
nucleoside phosphate catabolic process GO:1901292 412 0.064
glycerolipid biosynthetic process GO:0045017 51 0.064
maintenance of location GO:0051235 112 0.063
post embryonic development GO:0009791 2 0.063
nucleotide catabolic process GO:0009166 408 0.063
cellular ketone metabolic process GO:0042180 80 0.063
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.062
system process GO:0003008 349 0.061
chemical homeostasis GO:0048878 306 0.060
gtp metabolic process GO:0046039 239 0.059
ribonucleoside catabolic process GO:0042454 406 0.059
regulation of anatomical structure morphogenesis GO:0022603 286 0.059
ribonucleoside triphosphate catabolic process GO:0009203 391 0.058
regulation of cellular response to stress GO:0080135 244 0.056
regulation of cellular amine metabolic process GO:0033238 11 0.055
regulation of purine nucleotide metabolic process GO:1900542 264 0.055
regulation of cellular amino acid metabolic process GO:0006521 6 0.054
cellular response to interleukin 1 GO:0071347 35 0.054
purine nucleoside triphosphate catabolic process GO:0009146 392 0.054
cation homeostasis GO:0055080 189 0.053
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.053
ion homeostasis GO:0050801 230 0.053
positive regulation of hydrolase activity GO:0051345 331 0.052
cellular calcium ion homeostasis GO:0006874 117 0.051
cytokine mediated signaling pathway GO:0019221 109 0.051
positive regulation of catabolic process GO:0009896 310 0.051
glycerophospholipid metabolic process GO:0006650 84 0.050
cellular homeostasis GO:0019725 196 0.050
sequestering of metal ion GO:0051238 24 0.050
cellular metal ion homeostasis GO:0006875 146 0.049
phospholipid metabolic process GO:0006644 99 0.049
regulation of nucleotide catabolic process GO:0030811 205 0.049
sequestering of calcium ion GO:0051208 17 0.049
determination of adult lifespan GO:0008340 2 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.047
positive regulation of nucleoside metabolic process GO:0045979 186 0.047
positive regulation of cellular catabolic process GO:0031331 284 0.046
metal ion transport GO:0030001 272 0.046
cellular cation homeostasis GO:0030003 163 0.045
acrosome reaction GO:0007340 6 0.045
regulation of ion transport GO:0043269 189 0.043
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.042
enzyme linked receptor protein signaling pathway GO:0007167 303 0.042
anatomical structure formation involved in morphogenesis GO:0048646 284 0.042
regulation of jnk cascade GO:0046328 73 0.041
lipid biosynthetic process GO:0008610 177 0.041
female gamete generation GO:0007292 2 0.041
apoptotic signaling pathway GO:0097190 268 0.041
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.040
cellular divalent inorganic cation homeostasis GO:0072503 128 0.040
stress activated protein kinase signaling cascade GO:0031098 94 0.039
divalent inorganic cation transport GO:0072511 158 0.039
chromatin organization GO:0006325 351 0.038
small gtpase mediated signal transduction GO:0007264 78 0.037
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.037
positive regulation of stress activated mapk cascade GO:0032874 60 0.037
chromatin modification GO:0016568 298 0.037
divalent inorganic cation homeostasis GO:0072507 136 0.036
ras protein signal transduction GO:0007265 73 0.036
positive regulation of intracellular transport GO:0032388 104 0.035
negative regulation of protein metabolic process GO:0051248 391 0.035
response to interleukin 1 GO:0070555 47 0.034
blood circulation GO:0008015 113 0.034
cellular response to growth factor stimulus GO:0071363 197 0.034
jnk cascade GO:0007254 80 0.034
regulation of transferase activity GO:0051338 355 0.034
regulation of ion homeostasis GO:2000021 73 0.033
positive regulation of locomotion GO:0040017 186 0.033
positive regulation of ion transport GO:0043270 87 0.033
regulation of cytoplasmic transport GO:1903649 149 0.033
calcium ion transport GO:0006816 147 0.033
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.033
nervous system development GO:0007399 293 0.033
regulation of stress activated mapk cascade GO:0032872 84 0.032
response to growth factor GO:0070848 205 0.032
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
cellular protein complex assembly GO:0043623 188 0.032
regulation of intracellular transport GO:0032386 195 0.032
cellular response to dna damage stimulus GO:0006974 379 0.031
histone modification GO:0016570 251 0.031
regulation of cellular component movement GO:0051270 334 0.031
actin filament based process GO:0030029 224 0.031
positive regulation of developmental process GO:0051094 314 0.031
regulation of cell migration GO:0030334 289 0.031
covalent chromatin modification GO:0016569 254 0.031
positive regulation of transport GO:0051050 336 0.031
vesicle mediated transport GO:0016192 371 0.030
calcium ion homeostasis GO:0055074 122 0.030
secretion by cell GO:0032940 226 0.030
second messenger mediated signaling GO:0019932 78 0.030
negative regulation of phosphorus metabolic process GO:0010563 267 0.030
stress activated mapk cascade GO:0051403 93 0.030
positive regulation of cell motility GO:2000147 177 0.029
regulation of metal ion transport GO:0010959 120 0.029
regulation of cell motility GO:2000145 299 0.029
cellular component morphogenesis GO:0032989 314 0.029
secretion GO:0046903 254 0.028
divalent metal ion transport GO:0070838 152 0.028
regulation of locomotion GO:0040012 329 0.028
negative regulation of catalytic activity GO:0043086 335 0.028
phosphatidylinositol metabolic process GO:0046488 53 0.028
cell morphogenesis GO:0000902 296 0.027
cytosolic calcium ion homeostasis GO:0051480 89 0.027
negative regulation of cell proliferation GO:0008285 228 0.026
positive regulation of apoptotic process GO:0043065 246 0.026
phospholipid biosynthetic process GO:0008654 44 0.026
regulation of kinase activity GO:0043549 314 0.026
blood vessel morphogenesis GO:0048514 162 0.026
circulatory system process GO:0003013 113 0.026
positive regulation of cellular component movement GO:0051272 181 0.025
negative regulation of homeostatic process GO:0032845 59 0.025
rna processing GO:0006396 255 0.025
cellular response to interleukin 12 GO:0071349 3 0.025
regulation of calcium ion transport GO:0051924 79 0.025
intracellular protein transport GO:0006886 270 0.024
Yeast Mouse
positive regulation of cell migration GO:0030335 172 0.024
ameboidal type cell migration GO:0001667 135 0.024
locomotory behavior GO:0007626 1 0.024
regulation of cell differentiation GO:0045595 393 0.024
regulation of small gtpase mediated signal transduction GO:0051056 156 0.023
regulation of protein kinase activity GO:0045859 289 0.023
regulation of angiogenesis GO:0045765 92 0.023
protein autophosphorylation GO:0046777 123 0.023
oogenesis GO:0048477 2 0.023
mitotic cell cycle process GO:1903047 286 0.023
regulation of proteolysis GO:0030162 293 0.023
cell cycle phase transition GO:0044770 173 0.022
positive regulation of protein phosphorylation GO:0001934 313 0.022
regulation of protein serine threonine kinase activity GO:0071900 179 0.022
regulation of homeostatic process GO:0032844 121 0.021
glycerophospholipid biosynthetic process GO:0046474 40 0.021
positive regulation of calcium ion transport GO:0051928 51 0.021
regulation of blood vessel endothelial cell migration GO:0043535 30 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.021
regulation of calcium ion transport into cytosol GO:0010522 33 0.021
rho protein signal transduction GO:0007266 26 0.021
positive regulation of programmed cell death GO:0043068 249 0.021
negative regulation of wnt signaling pathway GO:0030178 69 0.021
regulation of epithelial cell migration GO:0010632 93 0.020
positive regulation of epithelial cell migration GO:0010634 55 0.020
tissue migration GO:0090130 119 0.020
negative regulation of protein modification process GO:0031400 200 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
single organism cellular localization GO:1902580 332 0.020
Yeast Mouse
positive regulation of cell death GO:0010942 263 0.020
protein catabolic process GO:0030163 325 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
regulation of cell morphogenesis GO:0022604 153 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
negative regulation of phosphate metabolic process GO:0045936 267 0.019
segmentation GO:0035282 4 0.019
growth GO:0040007 202 0.019
regulation of cell cycle GO:0051726 393 0.019
cardiovascular system development GO:0072358 262 0.019
single organism membrane organization GO:0044802 268 0.019
angiogenesis GO:0001525 147 0.019
negative regulation of sequestering of calcium ion GO:0051283 41 0.019
blood vessel development GO:0001568 172 0.019
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.019
regulation of sequestering of calcium ion GO:0051282 41 0.019
membrane organization GO:0061024 292 0.018
hippo signaling GO:0035329 20 0.018
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.018
phosphatidylinositol mediated signaling GO:0048015 55 0.018
cytoplasmic transport GO:0016482 379 0.018
Yeast Mouse
peptidyl serine phosphorylation GO:0018105 101 0.018
neuromuscular junction development GO:0007528 3 0.018
mitochondrion organization GO:0007005 156 0.018
regulation of protein localization GO:0032880 296 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.018
cellular macromolecule catabolic process GO:0044265 380 0.018
mitotic cell cycle GO:0000278 326 0.018
anterior posterior axis specification GO:0009948 2 0.018
negative regulation of transferase activity GO:0051348 124 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
vasculature development GO:0001944 181 0.018
interleukin 12 mediated signaling pathway GO:0035722 3 0.018
calcium ion transport into cytosol GO:0060402 48 0.018
release of sequestered calcium ion into cytosol GO:0051209 41 0.018
dephosphorylation GO:0016311 209 0.018
endothelial cell migration GO:0043542 86 0.018
cytosolic calcium ion transport GO:0060401 48 0.018
protein targeting GO:0006605 187 0.018
Yeast Mouse
cellular macromolecular complex assembly GO:0034622 324 0.018
cellular response to cytokine stimulus GO:0071345 181 0.017
regulation of vasculature development GO:1901342 97 0.017
positive regulation of endothelial cell migration GO:0010595 39 0.017
organelle assembly GO:0070925 176 0.017
negative regulation of developmental process GO:0051093 247 0.017
regulation of endothelial cell migration GO:0010594 67 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
neurogenesis GO:0022008 169 0.017
phosphatidylinositol biosynthetic process GO:0006661 25 0.017
calcium mediated signaling GO:0019722 44 0.017
compound eye development GO:0048749 1 0.017
epithelial cell migration GO:0010631 119 0.017
positive regulation of angiogenesis GO:0045766 51 0.017
peptidyl serine modification GO:0018209 106 0.016
epithelium migration GO:0090132 119 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.016
actin cytoskeleton organization GO:0030036 207 0.016
cell type specific apoptotic process GO:0097285 125 0.016
regulation of protein transport GO:0051223 213 0.016
mitotic cell cycle phase transition GO:0044772 162 0.016
spermatid development GO:0007286 4 0.016
cell development GO:0048468 328 0.016
regulation of cell cycle process GO:0010564 266 0.016
blastoderm segmentation GO:0007350 2 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
Yeast Mouse
endomembrane system organization GO:0010256 196 0.016
inositol lipid mediated signaling GO:0048017 55 0.016
oxidation reduction process GO:0055114 396 0.016
immune response GO:0006955 307 0.015
regeneration GO:0031099 4 0.015
oocyte differentiation GO:0009994 2 0.015
regulation of ras protein signal transduction GO:0046578 155 0.015
g1 s transition of mitotic cell cycle GO:0000082 78 0.015
regulation of cell growth GO:0001558 135 0.015
canonical wnt signaling pathway GO:0060070 116 0.015
adult locomotory behavior GO:0008344 1 0.015
wnt signaling pathway GO:0016055 156 0.015
microtubule based process GO:0007017 210 0.015
regulation of cellular component biogenesis GO:0044087 281 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
protein localization to organelle GO:0033365 280 0.014
Yeast Mouse
microtubule cytoskeleton organization GO:0000226 176 0.014
exocytosis GO:0006887 71 0.014
response to other organism GO:0051707 261 0.014
cell part morphogenesis GO:0032990 137 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
spermatid differentiation GO:0048515 4 0.014
negative regulation of kinase activity GO:0033673 106 0.014
regulation of growth GO:0040008 165 0.014
negative regulation of cell death GO:0060548 345 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
regulation of map kinase activity GO:0043405 108 0.014
carbohydrate metabolic process GO:0005975 207 0.014
establishment of protein localization to organelle GO:0072594 172 0.013
Yeast Mouse
interleukin 1 mediated signaling pathway GO:0070498 12 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
negative regulation of protein kinase activity GO:0006469 98 0.013
oocyte development GO:0048599 1 0.013
dna repair GO:0006281 198 0.013
ncrna processing GO:0034470 83 0.013
response to hormone GO:0009725 175 0.013
protein processing GO:0016485 226 0.013
neurological system process GO:0050877 163 0.013
cell growth GO:0016049 160 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
reproductive process GO:0022414 106 0.013
protein acylation GO:0043543 138 0.013
transmembrane transport GO:0055085 399 0.013
response to external biotic stimulus GO:0043207 261 0.013
memory GO:0007613 3 0.013
negative regulation of glial cell proliferation GO:0060253 2 0.013
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
regulation of cell projection organization GO:0031344 107 0.013
response to abiotic stimulus GO:0009628 336 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.013
ncrna metabolic process GO:0034660 108 0.013
regulation of cell development GO:0060284 161 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
positive regulation of calcium ion transport into cytosol GO:0010524 20 0.012
protein ubiquitination GO:0016567 314 0.012
regulation of canonical wnt signaling pathway GO:0060828 88 0.012
cell division GO:0051301 168 0.012
positive regulation of homeostatic process GO:0032846 47 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
immune system development GO:0002520 195 0.012
hemopoiesis GO:0030097 180 0.012
meiosis i GO:0007127 4 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
nerve development GO:0021675 4 0.012
erbb signaling pathway GO:0038127 44 0.012
cellular protein catabolic process GO:0044257 261 0.012
peptidyl lysine modification GO:0018205 144 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
neural tube formation GO:0001841 3 0.012
response to interleukin 13 GO:0035962 4 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
regulation of actin filament based process GO:0032970 141 0.012
single organism reproductive process GO:0044702 98 0.012
rna interference GO:0016246 4 0.012
cell projection organization GO:0030030 252 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
cell adhesion GO:0007155 325 0.012
positive regulation of transferase activity GO:0051347 227 0.012
positive regulation of ras gtpase activity GO:0032320 117 0.012
cellular response to oxidative stress GO:0034599 85 0.012
response to oxidative stress GO:0006979 121 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
protein localization to nucleus GO:0034504 136 0.011
Yeast Mouse
response to biotic stimulus GO:0009607 276 0.011
tripartite regional subdivision GO:0007351 2 0.011
nuclear export GO:0051168 69 0.011
regulation of neurogenesis GO:0050767 82 0.011
regulation of cytokine production GO:0001817 232 0.011
cell projection morphogenesis GO:0048858 129 0.011
regulation of peptidase activity GO:0052547 180 0.011
response to fungus GO:0009620 4 0.011
nuclear division GO:0000280 128 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
cation transmembrane transport GO:0098655 238 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
negative regulation of gliogenesis GO:0014014 3 0.011
protein maturation GO:0051604 233 0.011
neuron projection development GO:0031175 106 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
peripheral nervous system development GO:0007422 2 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
regulation of neuron differentiation GO:0045664 70 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
erk1 and erk2 cascade GO:0070371 104 0.011
innate immune response GO:0045087 178 0.011
associative learning GO:0008306 1 0.011
protein targeting to nucleus GO:0044744 104 0.011
Yeast Mouse
regulation of intracellular protein transport GO:0033157 123 0.011
protein import into nucleus GO:0006606 104 0.011
Yeast Mouse
cellular response to oxygen containing compound GO:1901701 276 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
positive regulation of organelle organization GO:0010638 195 0.011
regulation of binding GO:0051098 111 0.011
positive regulation of immune system process GO:0002684 283 0.010
cell cycle g1 s phase transition GO:0044843 80 0.010
embryo development GO:0009790 123 0.010
response to oxygen containing compound GO:1901700 369 0.010
regulation of protein maturation GO:1903317 150 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010
nuclear transport GO:0051169 179 0.010
Yeast Mouse
response to interleukin 12 GO:0070671 3 0.010
positive regulation of cell proliferation GO:0008284 301 0.010
protein acetylation GO:0006473 116 0.010
hindbrain development GO:0030902 3 0.010
cellular component disassembly GO:0022411 92 0.010
positive regulation of kinase activity GO:0033674 204 0.010
regulation of protein complex assembly GO:0043254 147 0.010

IPO11 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.017
eye and adnexa disease DOID:1492 150 0.017
nervous system disease DOID:863 431 0.017
eye disease DOID:5614 149 0.017
disease of metabolism DOID:0014667 295 0.015
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014
inherited metabolic disorder DOID:655 242 0.012
musculoskeletal system disease DOID:17 223 0.012
central nervous system disease DOID:331 186 0.012
retinal disease DOID:5679 118 0.011
retinal degeneration DOID:8466 89 0.011
immune system disease DOID:2914 155 0.010