Homo sapiens

115 known processes

IQGAP1

IQ motif containing GTPase activating protein 1

(Aliases: KIAA0051,SAR1,HUMORFA01,p195)

IQGAP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of actin filament polymerization GO:0030833 50 1.000
Human
actin filament organization GO:0007015 128 1.000
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.999
regulation of protein polymerization GO:0032271 63 0.998
Human
regulation of actin cytoskeleton organization GO:0032956 116 0.998
Human
positive regulation of cellular component organization GO:0051130 376 0.997
Human
endomembrane system organization GO:0010256 196 0.997
positive regulation of actin filament polymerization GO:0030838 38 0.997
Human
actin filament based process GO:0030029 224 0.997
Human
positive regulation of protein polymerization GO:0032273 45 0.994
Human
membrane organization GO:0061024 292 0.991
actin filament polymerization GO:0030041 45 0.988
Human
protein polymerization GO:0051258 71 0.988
Human
regulation of cytoskeleton organization GO:0051493 177 0.987
Human
epithelium development GO:0060429 227 0.987
actin polymerization or depolymerization GO:0008154 56 0.985
Human
regulation of actin filament length GO:0030832 56 0.985
Human
protein localization to organelle GO:0033365 280 0.984
positive regulation of cytoskeleton organization GO:0051495 83 0.983
Human
wound healing GO:0042060 115 0.982
positive regulation of organelle organization GO:0010638 195 0.980
Human
regulation of cellular component size GO:0032535 82 0.979
Human
single organism cellular localization GO:1902580 332 0.978
positive regulation of protein complex assembly GO:0031334 86 0.977
Human
small gtpase mediated signal transduction GO:0007264 78 0.976
syncytium formation by plasma membrane fusion GO:0000768 2 0.975
keratinocyte differentiation GO:0030216 36 0.971
regulation of cell adhesion GO:0030155 166 0.971
regulation of actin filament based process GO:0032970 141 0.969
Human
regulation of actin polymerization or depolymerization GO:0008064 56 0.965
Human
angiogenesis GO:0001525 147 0.964
actin cytoskeleton organization GO:0030036 207 0.964
Human
single organismal cell cell adhesion GO:0016337 148 0.962
cellular component morphogenesis GO:0032989 314 0.959
regulation of protein localization GO:0032880 296 0.955
cytokinesis GO:0000910 96 0.954
biological adhesion GO:0022610 331 0.953
cellular protein complex assembly GO:0043623 188 0.952
Human
regulation of transferase activity GO:0051338 355 0.935
organelle inheritance GO:0048308 2 0.932
single organism membrane organization GO:0044802 268 0.925
cell adhesion GO:0007155 325 0.924
protein targeting GO:0006605 187 0.894
protein localization to membrane GO:0072657 160 0.892
regulation of cellular component biogenesis GO:0044087 281 0.891
Human
purine nucleoside catabolic process GO:0006152 398 0.886
negative regulation of multicellular organismal process GO:0051241 317 0.886
positive regulation of cellular component biogenesis GO:0044089 158 0.883
Human
regulation of anatomical structure size GO:0090066 101 0.870
Human
muscle cell differentiation GO:0042692 63 0.867
single organism cell adhesion GO:0098602 179 0.857
growth GO:0040007 202 0.847
intracellular protein transport GO:0006886 270 0.838
post embryonic development GO:0009791 2 0.824
mapk cascade GO:0000165 288 0.819
tube development GO:0035295 125 0.818
peptidyl serine phosphorylation GO:0018105 101 0.804
nervous system development GO:0007399 293 0.803
positive regulation of wound healing GO:0090303 20 0.797
cellular macromolecular complex assembly GO:0034622 324 0.797
Human
regulation of cell morphogenesis GO:0022604 153 0.796
regulation of wound healing GO:0061041 56 0.791
tube morphogenesis GO:0035239 95 0.789
negative regulation of endopeptidase activity GO:0010951 84 0.786
positive regulation of cellular amine metabolic process GO:0033240 7 0.785
peptidyl tyrosine modification GO:0018212 170 0.767
signal transduction by phosphorylation GO:0023014 297 0.766
cytoplasmic transport GO:0016482 379 0.763
epithelial cell differentiation GO:0030855 141 0.759
vesicle mediated transport GO:0016192 371 0.751
embryonic morphogenesis GO:0048598 85 0.751
protein targeting to nucleus GO:0044744 104 0.742
synaptic vesicle endocytosis GO:0048488 2 0.734
actin nucleation GO:0045010 21 0.722
Human
positive regulation of protein localization to nucleus GO:1900182 48 0.719
negative regulation of protein processing GO:0010955 142 0.718
embryo development GO:0009790 123 0.715
muscle structure development GO:0061061 98 0.712
regulation of peptidase activity GO:0052547 180 0.711
ameboidal type cell migration GO:0001667 135 0.710
response to wounding GO:0009611 168 0.699
positive regulation of map kinase activity GO:0043406 80 0.699
positive regulation of cell proliferation GO:0008284 301 0.697
plasma membrane organization GO:0007009 115 0.692
cellular response to ammonium ion GO:0071242 4 0.691
regulation of protein targeting GO:1903533 91 0.691
generation of neurons GO:0048699 152 0.689
blood vessel development GO:0001568 172 0.688
protein localization to nucleus GO:0034504 136 0.686
regulation of protein transport GO:0051223 213 0.682
determination of adult lifespan GO:0008340 2 0.681
positive regulation of transport GO:0051050 336 0.680
microtubule based process GO:0007017 210 0.679
regulation of cytokine production GO:0001817 232 0.679
Mouse
peptidyl serine modification GO:0018209 106 0.677
cell development GO:0048468 328 0.663
regulation of kinase activity GO:0043549 314 0.663
glycosyl compound catabolic process GO:1901658 413 0.655
regulation of protein import into nucleus GO:0042306 78 0.650
neuron projection development GO:0031175 106 0.648
positive regulation of intracellular protein transport GO:0090316 76 0.646
organelle fission GO:0048285 149 0.645
Worm
cell morphogenesis GO:0000902 296 0.643
epidermal cell differentiation GO:0009913 45 0.633
regulation of mapk cascade GO:0043408 262 0.633
establishment of protein localization to organelle GO:0072594 172 0.631
regulation of cell projection organization GO:0031344 107 0.626
cellular amino acid metabolic process GO:0006520 116 0.625
vesicle organization GO:0016050 62 0.616
negative regulation of protein maturation GO:1903318 142 0.615
myotube differentiation GO:0014902 22 0.608
microtubule cytoskeleton organization GO:0000226 176 0.601
glial cell migration GO:0008347 4 0.599
cellular response to organic cyclic compound GO:0071407 127 0.599
chordate embryonic development GO:0043009 34 0.597
myoblast fusion GO:0007520 1 0.594
epithelial tube morphogenesis GO:0060562 38 0.589
mitochondrion distribution GO:0048311 3 0.588
regulation of cell motility GO:2000145 299 0.570
cell type specific apoptotic process GO:0097285 125 0.564
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.559
negative regulation of catalytic activity GO:0043086 335 0.559
regulation of neurogenesis GO:0050767 82 0.558
cellular response to endogenous stimulus GO:0071495 336 0.557
activation of mapk activity GO:0000187 45 0.552
positive regulation of developmental process GO:0051094 314 0.550
membrane budding GO:0006900 28 0.546
dna replication GO:0006260 116 0.543
oogenesis GO:0048477 2 0.542
purine ribonucleoside catabolic process GO:0046130 398 0.537
regulation of cell differentiation GO:0045595 393 0.535
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.534
digestive tract development GO:0048565 75 0.527
positive regulation of transferase activity GO:0051347 227 0.523
regulation of establishment of protein localization GO:0070201 242 0.516
establishment of organelle localization GO:0051656 59 0.514
purine nucleoside triphosphate catabolic process GO:0009146 392 0.510
regulation of cell migration GO:0030334 289 0.509
nuclear import GO:0051170 106 0.508
purine ribonucleoside metabolic process GO:0046128 437 0.505
cell migration involved in gastrulation GO:0042074 1 0.500
establishment or maintenance of cell polarity GO:0007163 31 0.498
organelle assembly GO:0070925 176 0.498
endocytosis GO:0006897 159 0.494
tissue morphogenesis GO:0048729 96 0.494
positive regulation of neutrophil apoptotic process GO:0033031 1 0.490
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.489
leukocyte migration GO:0050900 107 0.484
ribonucleoside catabolic process GO:0042454 406 0.480
regulation of cellular amine metabolic process GO:0033238 11 0.479
positive regulation of cell migration GO:0030335 172 0.479
mitotic cell cycle process GO:1903047 286 0.466
vasculature development GO:0001944 181 0.465
positive regulation of mapk cascade GO:0043410 190 0.464
epidermis development GO:0008544 59 0.462
organophosphate catabolic process GO:0046434 430 0.457
morphogenesis of embryonic epithelium GO:0016331 4 0.453
regulation of protein complex assembly GO:0043254 147 0.450
Human
positive regulation of rac gtpase activity GO:0032855 31 0.446
organelle localization GO:0051640 84 0.443
monocyte activation GO:0042117 3 0.440
negative regulation of phosphate metabolic process GO:0045936 267 0.438
Mouse
developmental growth GO:0048589 48 0.431
female gamete generation GO:0007292 2 0.428
embryonic epithelial tube formation GO:0001838 4 0.425
oocyte differentiation GO:0009994 2 0.412
regulation of vesicle mediated transport GO:0060627 130 0.405
regulation of anatomical structure morphogenesis GO:0022603 286 0.404
cellular amine metabolic process GO:0044106 41 0.404
secretion GO:0046903 254 0.399
Worm
cell projection assembly GO:0030031 126 0.399
protein import GO:0017038 130 0.392
ras protein signal transduction GO:0007265 73 0.390
activation of protein kinase activity GO:0032147 90 0.390
regulation of small gtpase mediated signal transduction GO:0051056 156 0.387
regulation of map kinase activity GO:0043405 108 0.386
regulation of locomotion GO:0040012 329 0.379
regulation of cellular amino acid metabolic process GO:0006521 6 0.373
regulation of protein processing GO:0070613 150 0.371
cell projection organization GO:0030030 252 0.360
filopodium assembly GO:0046847 18 0.360
negative regulation of peptidase activity GO:0010466 91 0.358
nucleoside triphosphate metabolic process GO:0009141 422 0.358
positive regulation of apoptotic signaling pathway GO:2001235 70 0.357
positive regulation of protein import into nucleus GO:0042307 46 0.356
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.356
cellular response to growth factor stimulus GO:0071363 197 0.354
neuromuscular junction development GO:0007528 3 0.350
ubiquitin dependent protein catabolic process GO:0006511 206 0.349
atp metabolic process GO:0046034 176 0.346
branching morphogenesis of an epithelial tube GO:0048754 19 0.345
positive regulation of programmed cell death GO:0043068 249 0.344
regulation of intracellular protein transport GO:0033157 123 0.344
regulation of intracellular transport GO:0032386 195 0.339
regulation of synaptic vesicle transport GO:1902803 3 0.338
response to organic cyclic compound GO:0014070 204 0.336
positive regulation of cell death GO:0010942 263 0.336
regulation of growth GO:0040008 165 0.333
purine nucleotide catabolic process GO:0006195 405 0.332
positive regulation of cellular component movement GO:0051272 181 0.330
digestive tract morphogenesis GO:0048546 56 0.329
negative regulation of proteolysis GO:0045861 132 0.325
viral budding GO:0046755 9 0.325
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.323
cell division GO:0051301 168 0.322
mitotic cell cycle GO:0000278 326 0.320
leukocyte activation GO:0045321 164 0.320
regulation of lymphocyte migration GO:2000401 22 0.318
peptidyl tyrosine phosphorylation GO:0018108 170 0.316
cell activation GO:0001775 213 0.314
regulation of proteolysis GO:0030162 293 0.314
neural tube formation GO:0001841 3 0.314
protein autophosphorylation GO:0046777 123 0.313
negative regulation of hydrolase activity GO:0051346 182 0.304
regulation of protein serine threonine kinase activity GO:0071900 179 0.302
enzyme linked receptor protein signaling pathway GO:0007167 303 0.302
neuron differentiation GO:0030182 138 0.301
blood vessel morphogenesis GO:0048514 162 0.300
regulation of protein maturation GO:1903317 150 0.299
nucleoside catabolic process GO:0009164 408 0.291
cytoskeleton dependent cytokinesis GO:0061640 22 0.290
morphogenesis of an epithelium GO:0002009 60 0.289
regulation of nervous system development GO:0051960 88 0.281
activation of mapkk activity GO:0000186 18 0.281
cytokinetic process GO:0032506 12 0.278
immune system development GO:0002520 195 0.275
regulation of synaptic vesicle exocytosis GO:2000300 2 0.275
positive regulation of actin filament bundle assembly GO:0032233 25 0.274
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.271
lymphocyte migration GO:0072676 28 0.270
regulation of nucleocytoplasmic transport GO:0046822 98 0.267
negative regulation of trophoblast cell migration GO:1901164 3 0.267
maintenance of protein location in cell GO:0032507 56 0.265
single organism nuclear import GO:1902593 104 0.262
regulation of protein localization to nucleus GO:1900180 85 0.262
regulation of cell cell adhesion mediated by cadherin GO:2000047 4 0.261
multicellular organismal aging GO:0010259 3 0.259
epithelial cell migration GO:0010631 119 0.257
nucleoside triphosphate catabolic process GO:0009143 394 0.255
positive regulation of protein kinase activity GO:0045860 190 0.253
cell growth GO:0016049 160 0.253
negative regulation of cellular component movement GO:0051271 106 0.249
gastrulation GO:0007369 51 0.248
morphogenesis of a branching structure GO:0001763 21 0.247
digestive system development GO:0055123 75 0.247
exocytosis GO:0006887 71 0.247
ribonucleoside monophosphate catabolic process GO:0009158 158 0.246
atp catabolic process GO:0006200 157 0.245
amine metabolic process GO:0009308 44 0.244
protein modification by small protein conjugation GO:0032446 342 0.243
regulation of endopeptidase activity GO:0052548 170 0.242
oocyte development GO:0048599 1 0.240
nucleocytoplasmic transport GO:0006913 176 0.240
negative regulation of cytoskeleton organization GO:0051494 45 0.237
actin filament capping GO:0051693 4 0.237
nucleoside phosphate catabolic process GO:1901292 412 0.235
establishment of neuroblast polarity GO:0045200 1 0.234
positive regulation of cell motility GO:2000147 177 0.230
negative regulation of serine type peptidase activity GO:1902572 2 0.230
dendritic spine morphogenesis GO:0060997 3 0.224
modification dependent protein catabolic process GO:0019941 209 0.223
negative regulation of protein transport GO:0051224 75 0.220
negative regulation of transport GO:0051051 176 0.218
cellular response to nitrogen compound GO:1901699 144 0.215
immune response activating signal transduction GO:0002757 90 0.214
neuron development GO:0048666 113 0.213
negative regulation of actin filament polymerization GO:0030837 10 0.212
establishment of protein localization to membrane GO:0090150 121 0.211
ribonucleoside triphosphate catabolic process GO:0009203 391 0.211
negative regulation of protein metabolic process GO:0051248 391 0.210
cardiovascular system development GO:0072358 262 0.210
protein import into nucleus GO:0006606 104 0.208
positive regulation of hydrolase activity GO:0051345 331 0.207
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.206
pattern specification process GO:0007389 43 0.206
regulation of endocytosis GO:0030100 72 0.205
system process GO:0003008 349 0.204
protein maturation GO:0051604 233 0.203
protein processing GO:0016485 226 0.203
striated muscle cell differentiation GO:0051146 43 0.201
ribonucleoside triphosphate metabolic process GO:0009199 412 0.200
positive regulation of protein phosphorylation GO:0001934 313 0.200
negative regulation of cellular protein metabolic process GO:0032269 353 0.196
reproductive process GO:0022414 106 0.196
regulation of protein kinase activity GO:0045859 289 0.195
apoptotic signaling pathway GO:0097190 268 0.194
positive regulation of response to wounding GO:1903036 28 0.193
purine ribonucleotide catabolic process GO:0009154 404 0.193
nucleoside monophosphate catabolic process GO:0009125 159 0.189
response to hormone GO:0009725 175 0.189
single organism reproductive process GO:0044702 98 0.186
negative regulation of cell proliferation GO:0008285 228 0.185
organophosphate biosynthetic process GO:0090407 163 0.185
engulfment of apoptotic cell GO:0043652 2 0.185
regulation of exocytosis GO:0017157 46 0.178
protein catabolic process GO:0030163 325 0.177
response to inorganic substance GO:0010035 127 0.176
negative regulation of chondrocyte proliferation GO:1902731 1 0.173
extrinsic apoptotic signaling pathway GO:0097191 119 0.171
negative regulation of locomotion GO:0040013 118 0.170
ribonucleotide catabolic process GO:0009261 405 0.169
ribonucleoside monophosphate metabolic process GO:0009161 187 0.169
vesicle localization GO:0051648 26 0.166
kidney development GO:0001822 53 0.158
positive regulation of cell adhesion GO:0045785 84 0.157
circulatory system development GO:0072359 262 0.152
response to organonitrogen compound GO:0010243 156 0.151
anterior posterior axis specification embryo GO:0008595 2 0.150
regulation of cell cell adhesion GO:0022407 57 0.149
negative regulation of cell migration GO:0030336 102 0.148
muscle cell development GO:0055001 29 0.148
positive regulation of nucleotide catabolic process GO:0030813 185 0.146
leukocyte differentiation GO:0002521 98 0.141
synaptic vesicle exocytosis GO:0016079 3 0.140
positive regulation of phosphorylation GO:0042327 394 0.138
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.137
regulation of cell growth GO:0001558 135 0.137
mitotic nuclear division GO:0007067 119 0.134
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.133
Mouse
positive regulation of nucleotide metabolic process GO:0045981 230 0.130
establishment of cell polarity GO:0030010 22 0.130
actomyosin structure organization GO:0031032 59 0.128
negative regulation of intracellular signal transduction GO:1902532 183 0.128
cellular protein catabolic process GO:0044257 261 0.128
guanosine containing compound metabolic process GO:1901068 244 0.128
tissue migration GO:0090130 119 0.126
purine nucleoside triphosphate metabolic process GO:0009144 412 0.126
positive regulation of apoptotic process GO:0043065 246 0.125
spermatid differentiation GO:0048515 4 0.124
regulation of cellular ketone metabolic process GO:0010565 50 0.123
negative regulation of programmed cell death GO:0043069 321 0.123
regulation of cell cycle GO:0051726 393 0.123
tissue regeneration GO:0042246 3 0.122
striated muscle tissue development GO:0014706 59 0.121
negative regulation of apoptotic signaling pathway GO:2001234 97 0.121
urogenital system development GO:0001655 65 0.119
regulation of cytoplasmic transport GO:1903649 149 0.119
immune response GO:0006955 307 0.119
cellular macromolecule catabolic process GO:0044265 380 0.118
regulation of cell projection assembly GO:0060491 47 0.118
spermatid development GO:0007286 4 0.116
neuron projection morphogenesis GO:0048812 50 0.115
regulation of neuron projection development GO:0010975 57 0.115
nucleoside monophosphate metabolic process GO:0009123 191 0.114
myeloid cell differentiation GO:0030099 117 0.113
regulation of apoptotic signaling pathway GO:2001233 175 0.112
negative regulation of cell death GO:0060548 345 0.111
blood vessel maturation GO:0001955 1 0.111
negative regulation of protein complex assembly GO:0031333 43 0.111
arp2 3 complex mediated actin nucleation GO:0034314 17 0.110
Human
regulation of peroxidase activity GO:2000468 2 0.108
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.108
cellular response to dna damage stimulus GO:0006974 379 0.106
regulation of synaptic vesicle endocytosis GO:1900242 1 0.106
specification of axis polarity GO:0065001 1 0.105
peptidyl tyrosine dephosphorylation GO:0035335 36 0.105
sterol transport GO:0015918 39 0.105
negative regulation of dna metabolic process GO:0051053 57 0.104
maintenance of protein location GO:0045185 57 0.104
blastoderm segmentation GO:0007350 2 0.104
actin filament bundle organization GO:0061572 54 0.104
neutrophil apoptotic process GO:0001781 2 0.103
regulation of synaptic vesicle recycling GO:1903421 1 0.103
muscle fiber development GO:0048747 16 0.102
regulation of multi organism process GO:0043900 157 0.101
positive regulation of kinase activity GO:0033674 204 0.100
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.100
motor neuron axon guidance GO:0008045 2 0.100
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.100
actin mediated cell contraction GO:0070252 12 0.099
regulation of phospholipase a2 activity GO:0032429 4 0.099
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.098
mitral valve development GO:0003174 3 0.096
regulation of stress fiber assembly GO:0051492 32 0.096
positive regulation of intracellular transport GO:0032388 104 0.095
maintenance of cell polarity GO:0030011 2 0.095
nuclear transport GO:0051169 179 0.094
response to growth factor GO:0070848 205 0.093
endosomal transport GO:0016197 129 0.093
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.092
regulation of dendrite morphogenesis GO:0048814 11 0.092
positive regulation of rho gtpase activity GO:0032321 56 0.092
negative regulation of organelle organization GO:0010639 126 0.091
positive regulation of nucleoside metabolic process GO:0045979 186 0.091
locomotory behavior GO:0007626 1 0.090
regulation of dna metabolic process GO:0051052 153 0.090
response to steroid hormone GO:0048545 80 0.090
mesonephric tubule morphogenesis GO:0072171 10 0.090
regulation of jnk cascade GO:0046328 73 0.090
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.089
regulation of cysteine type endopeptidase activity GO:2000116 127 0.088
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.088
developmental process involved in reproduction GO:0003006 66 0.088
regulation of serine type peptidase activity GO:1902571 2 0.087
cardiac muscle cell fate commitment GO:0060923 4 0.086
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.086
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.085
negative regulation of actin nucleation GO:0051126 3 0.085
macrophage fusion GO:0034238 1 0.085
positive regulation of exocytosis GO:0045921 35 0.085
regulation of neutrophil apoptotic process GO:0033029 1 0.084
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.083
response to external biotic stimulus GO:0043207 261 0.083
segmentation GO:0035282 4 0.083
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.082
skeletal system development GO:0001501 79 0.082
cell junction organization GO:0034330 79 0.081
microtubule based movement GO:0007018 32 0.081
regulation of cell matrix adhesion GO:0001952 42 0.081
regulation of dendritic spine development GO:0060998 5 0.081
cell fate commitment GO:0045165 27 0.080
regulation of cellular component movement GO:0051270 334 0.079
regulation of cellular response to stress GO:0080135 244 0.079
cellular response to oxygen containing compound GO:1901701 276 0.079
regulation of microtubule based process GO:0032886 74 0.079
chemotaxis GO:0006935 157 0.078
negative regulation of protein phosphorylation GO:0001933 140 0.078
embryonic placenta development GO:0001892 1 0.078
positive regulation of growth GO:0045927 58 0.077
blood coagulation GO:0007596 76 0.076
cell cell adhesion mediated by cadherin GO:0044331 4 0.075
positive regulation of fibroblast migration GO:0010763 3 0.075
epithelium migration GO:0090132 119 0.075
response to lipid GO:0033993 206 0.075
hair follicle morphogenesis GO:0031069 2 0.075
cytokine production GO:0001816 247 0.075
Mouse
positive regulation of axon extension GO:0045773 4 0.073
positive regulation of cell growth GO:0030307 48 0.073
morphogenesis of a branching epithelium GO:0061138 20 0.073
regulation of neuron apoptotic process GO:0043523 35 0.072
response to abiotic stimulus GO:0009628 336 0.072
regulation of actin nucleation GO:0051125 10 0.072
negative regulation of developmental process GO:0051093 247 0.072
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.072
actin cytoskeleton reorganization GO:0031532 37 0.071
response to nitrosative stress GO:0051409 4 0.070
positive regulation of protein transport GO:0051222 135 0.070
purine nucleoside monophosphate metabolic process GO:0009126 186 0.068
actin filament bundle assembly GO:0051017 54 0.068
mitotic cell cycle phase transition GO:0044772 162 0.068
neuroblast proliferation GO:0007405 4 0.068
regulation of establishment of planar polarity GO:0090175 5 0.067
skin development GO:0043588 76 0.067
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.067
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.067
cellular response to glucocorticoid stimulus GO:0071385 4 0.067
regulation of dendrite development GO:0050773 18 0.067
response to fibroblast growth factor GO:0071774 39 0.067
Mouse
neuroblast division GO:0055057 1 0.066
epithelial cell morphogenesis GO:0003382 8 0.066
positive regulation of jnk cascade GO:0046330 52 0.066
neurogenesis GO:0022008 169 0.066
response to other organism GO:0051707 261 0.065
regulation of nucleoside metabolic process GO:0009118 209 0.064
regulation of protein secretion GO:0050708 86 0.064
syncytium formation GO:0006949 4 0.064
negative regulation of mapk cascade GO:0043409 56 0.063
modification dependent macromolecule catabolic process GO:0043632 212 0.062
cerebral cortex cell migration GO:0021795 3 0.062
regulation of ras protein signal transduction GO:0046578 155 0.062
response to corticosteroid GO:0031960 15 0.062
blood circulation GO:0008015 113 0.061
regulation of t cell chemotaxis GO:0010819 7 0.061
negative regulation of cell motility GO:2000146 104 0.061
rho protein signal transduction GO:0007266 26 0.061
memory GO:0007613 3 0.060
response to biotic stimulus GO:0009607 276 0.060
positive regulation of cytoplasmic transport GO:1903651 82 0.060
elastic fiber assembly GO:0048251 3 0.060
regulation of stress activated mapk cascade GO:0032872 84 0.060
t cell activation GO:0042110 99 0.060
establishment of planar polarity GO:0001736 3 0.060
cell morphogenesis involved in differentiation GO:0000904 144 0.060
maintenance of location in cell GO:0051651 62 0.060
purine containing compound catabolic process GO:0072523 411 0.059
cellular ion homeostasis GO:0006873 168 0.059
regulation of neuron death GO:1901214 56 0.058
reproduction GO:0000003 63 0.058
Worm
cell chemotaxis GO:0060326 112 0.058
jnk cascade GO:0007254 80 0.058
regulation of peptidyl serine phosphorylation GO:0033135 50 0.058
regulation of neuron differentiation GO:0045664 70 0.057
negative regulation of apoptotic process GO:0043066 316 0.057

IQGAP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
kidney disease DOID:557 36 0.914
urinary system disease DOID:18 40 0.914
sensory system disease DOID:0050155 203 0.581
nervous system disease DOID:863 431 0.581
central nervous system disease DOID:331 186 0.192
neurodegenerative disease DOID:1289 102 0.192
disease of cellular proliferation DOID:14566 174 0.171
auditory system disease DOID:2742 53 0.146
autosomal dominant nonsyndromic deafness DOID:0050564 23 0.146
nonsyndromic deafness DOID:0050563 50 0.146
cancer DOID:162 167 0.143
neuropathy DOID:870 52 0.114
organ system cancer DOID:0050686 164 0.066