|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
1.000
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
1.000
|
|
|
|
cellular response to bacterial lipoprotein
|
GO:0071220 |
3 |
1.000
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
1.000
|
Human |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
1.000
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
1.000
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.999
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.999
|
|
|
|
positive regulation of toll like receptor 4 signaling pathway
|
GO:0034145 |
6 |
0.999
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.999
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.999
|
Human |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.999
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.999
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.999
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.999
|
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
4 |
0.999
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.998
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.998
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.998
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.998
|
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.997
|
Human |
|
|
growth of symbiont in host
|
GO:0044117 |
1 |
0.997
|
|
|
|
positive regulation of toll like receptor signaling pathway
|
GO:0034123 |
10 |
0.996
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
25 |
0.995
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.994
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.993
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.993
|
|
|
|
positive regulation of toll like receptor 3 signaling pathway
|
GO:0034141 |
1 |
0.992
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.992
|
Human Mouse |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.990
|
Human Mouse Rat |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.989
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.988
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.986
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.985
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.985
|
|
|
|
response to bacterial lipopeptide
|
GO:0070339 |
3 |
0.984
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.979
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.978
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.973
|
|
|
|
regulation of type i interferon production
|
GO:0032479 |
26 |
0.973
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.968
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
4 |
0.966
|
|
|
|
positive regulation of interleukin 23 production
|
GO:0032747 |
4 |
0.965
|
|
|
|
positive regulation of toll like receptor 2 signaling pathway
|
GO:0034137 |
2 |
0.956
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.956
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.954
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.954
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.953
|
Human |
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
2 |
0.953
|
|
|
|
cellular response to bacterial lipopeptide
|
GO:0071221 |
3 |
0.947
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
2 |
0.947
|
|
|
|
modulation of growth of symbiont involved in interaction with host
|
GO:0044144 |
2 |
0.946
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.946
|
|
|
|
response to peptidoglycan
|
GO:0032494 |
3 |
0.944
|
Mouse |
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
4 |
0.944
|
|
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.941
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.941
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.933
|
Human |
|
|
type i interferon production
|
GO:0032606 |
27 |
0.924
|
|
|
|
negative regulation of tumor necrosis factor production
|
GO:0032720 |
20 |
0.923
|
Human |
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.919
|
Human |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.917
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
37 |
0.913
|
Human |
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.897
|
Human |
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.889
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.875
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
26 |
0.869
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.861
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
2 |
0.855
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.848
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
15 |
0.839
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.834
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.826
|
|
|
|
interleukin 17 production
|
GO:0032620 |
12 |
0.807
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.805
|
|
|
|
mrna stabilization
|
GO:0048255 |
18 |
0.784
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.783
|
Human |
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.782
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.782
|
|
|
|
type i interferon biosynthetic process
|
GO:0045351 |
4 |
0.782
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.775
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.763
|
|
|
|
activation of nf kappab inducing kinase activity
|
GO:0007250 |
9 |
0.751
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.731
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.727
|
Human |
|
|
regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031664 |
13 |
0.717
|
|
|
|
regulation of interleukin 17 production
|
GO:0032660 |
12 |
0.714
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
22 |
0.698
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.670
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.663
|
|
|
|
negative regulation of tumor necrosis factor mediated signaling pathway
|
GO:0010804 |
7 |
0.640
|
|
|
|
toll signaling pathway
|
GO:0008063 |
2 |
0.632
|
|
|
|
response to bacterial lipoprotein
|
GO:0032493 |
3 |
0.629
|
|
|
|
negative regulation of interleukin 12 production
|
GO:0032695 |
6 |
0.622
|
Human |
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.595
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.590
|
|
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
4 |
0.589
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.586
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.560
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.551
|
|
|
|
interleukin 1 mediated signaling pathway
|
GO:0070498 |
12 |
0.548
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.543
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.542
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.532
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.525
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.525
|
|
|
|
regulation of nik nf kappab signaling
|
GO:1901222 |
11 |
0.524
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.519
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.514
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.509
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.497
|
|
|
|
negative regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903556 |
20 |
0.495
|
Human |
|
|
regulation of chemokine biosynthetic process
|
GO:0045073 |
4 |
0.483
|
|
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
2 |
0.482
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.482
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
21 |
0.474
|
|
|
|
interleukin 12 production
|
GO:0032615 |
15 |
0.473
|
Human |
|
|
chemokine biosynthetic process
|
GO:0042033 |
4 |
0.469
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.463
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.457
|
Rat |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.454
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.440
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.424
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.417
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.414
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.409
|
Human |
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.408
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.408
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.406
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.399
|
Human |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.393
|
Mouse |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.393
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.390
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.389
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.383
|
|
|
|
3 utr mediated mrna stabilization
|
GO:0070935 |
8 |
0.381
|
|
|
|
regulation of tumor necrosis factor mediated signaling pathway
|
GO:0010803 |
12 |
0.376
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.363
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.363
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.360
|
|
|
|
positive regulation of chemokine biosynthetic process
|
GO:0045080 |
3 |
0.358
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.345
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.342
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
25 |
0.342
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.332
|
Human |
|
|
antifungal humoral response
|
GO:0019732 |
2 |
0.321
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.315
|
Human |
|
|
toll like receptor 3 signaling pathway
|
GO:0034138 |
4 |
0.315
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.306
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.303
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.299
|
Mouse |
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
36 |
0.299
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.290
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.284
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.281
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.279
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.276
|
Human |
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
14 |
0.273
|
Rat |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.270
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.269
|
|
|
|
positive regulation of interferon beta biosynthetic process
|
GO:0045359 |
4 |
0.266
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
12 |
0.259
|
Mouse |
|
|
response to fungus
|
GO:0009620 |
4 |
0.258
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.255
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.254
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.247
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.246
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.233
|
Human |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.230
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.229
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
20 |
0.226
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.223
|
Rat |
|
|
positive regulation of protein binding
|
GO:0032092 |
24 |
0.222
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.221
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.221
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.216
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.214
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.213
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
12 |
0.203
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.198
|
Human |
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
17 |
0.198
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.197
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
12 |
0.196
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.194
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.191
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.190
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.188
|
|
|
|
i kappab phosphorylation
|
GO:0007252 |
7 |
0.178
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.178
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.175
|
Mouse |
|
|
myeloid dendritic cell activation
|
GO:0001773 |
4 |
0.174
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.174
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.170
|
|
|
|
detection of bacterial lipoprotein
|
GO:0042494 |
3 |
0.169
|
|
|
|
cellular response to triacyl bacterial lipopeptide
|
GO:0071727 |
2 |
0.166
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.165
|
|
|
|
macrophage cytokine production
|
GO:0010934 |
4 |
0.165
|
|
|
|
regulation of interferon alpha production
|
GO:0032647 |
11 |
0.164
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.163
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.157
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.156
|
Human |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.154
|
Mouse Rat |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.150
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.149
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.147
|
Human |
|
|
negative regulation of toll signaling pathway
|
GO:0045751 |
1 |
0.142
|
|
|
|
positive regulation of interleukin 4 production
|
GO:0032753 |
3 |
0.141
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.140
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.135
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.131
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.130
|
Mouse |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.130
|
|
|
|
regulation of toll signaling pathway
|
GO:0008592 |
1 |
0.129
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.129
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.127
|
Mouse |
|
|
positive regulation of cytokine mediated signaling pathway
|
GO:0001961 |
12 |
0.127
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
19 |
0.127
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
1 |
0.124
|
|
|
|
detection of diacyl bacterial lipopeptide
|
GO:0042496 |
2 |
0.124
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
18 |
0.124
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.123
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.122
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.122
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.119
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.118
|
Rat |
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.116
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.116
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.114
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.113
|
|
|
|
positive regulation of nik nf kappab signaling
|
GO:1901224 |
10 |
0.112
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.111
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.109
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
11 |
0.105
|
|
|
|
response to triacyl bacterial lipopeptide
|
GO:0071725 |
2 |
0.104
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.104
|
|
|
|
regulation of interferon beta production
|
GO:0032648 |
22 |
0.102
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.099
|
Human |
|
|
defense response to gram negative bacterium
|
GO:0050829 |
14 |
0.098
|
|
|
|
chemokine metabolic process
|
GO:0050755 |
4 |
0.098
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.098
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.096
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.095
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.094
|
|
|
|
negative regulation of macrophage cytokine production
|
GO:0010936 |
3 |
0.093
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.091
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
3 |
0.088
|
|
|
|
positive regulation of interleukin 6 biosynthetic process
|
GO:0045410 |
1 |
0.087
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.087
|
Mouse Rat |
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.086
|
|
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
9 |
0.085
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.085
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.084
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.083
|
|
|
|
interleukin 6 biosynthetic process
|
GO:0042226 |
5 |
0.082
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.082
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.081
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.081
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.081
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.081
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.080
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.078
|
Human Mouse |
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.078
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.077
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.076
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.074
|
Human |
|
|
rna stabilization
|
GO:0043489 |
18 |
0.073
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.073
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.072
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.071
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.071
|
|
|
|
growth
|
GO:0040007 |
202 |
0.070
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.070
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
12 |
0.069
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
1 |
0.069
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
1 |
0.069
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.069
|
Rat |
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
27 |
0.068
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.068
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.066
|
Mouse |
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.065
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.065
|
|
|
|
cellular response to diacyl bacterial lipopeptide
|
GO:0071726 |
2 |
0.065
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.063
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.063
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.062
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
17 |
0.061
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.059
|
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.058
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.058
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.058
|
Human |
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
1 |
0.058
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.057
|
|
|
|
positive regulation of t cell cytokine production
|
GO:0002726 |
4 |
0.057
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.056
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.056
|
Mouse Rat |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.055
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.055
|
|
|
|
regulation of toll like receptor 3 signaling pathway
|
GO:0034139 |
2 |
0.055
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
4 |
0.055
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.054
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.053
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
11 |
0.053
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.052
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.052
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.052
|
|
|
|
interleukin 4 biosynthetic process
|
GO:0042097 |
2 |
0.052
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.051
|
|
|
|
negative regulation of interleukin 6 production
|
GO:0032715 |
13 |
0.050
|
Human |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.049
|
Human |
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
21 |
0.049
|
|
|
|
negative regulation of type i interferon production
|
GO:0032480 |
5 |
0.049
|
|
|
|
interferon beta production
|
GO:0032608 |
23 |
0.049
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.047
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.047
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.046
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.046
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.046
|
Mouse |
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.045
|
|
|
|
regulation of interleukin 6 biosynthetic process
|
GO:0045408 |
5 |
0.045
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.045
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.043
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.043
|
|
|
|
detection of bacterial lipopeptide
|
GO:0070340 |
3 |
0.043
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.043
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.043
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.043
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.042
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.042
|
|
|
|
glycosylation
|
GO:0070085 |
71 |
0.041
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.041
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.041
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.041
|
|
|
|
positive regulation of lipid storage
|
GO:0010884 |
10 |
0.040
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.040
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.040
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.040
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.040
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.040
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.040
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.039
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.039
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.039
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.039
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.039
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.039
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.039
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.039
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.039
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.039
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.038
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.038
|
Mouse |
|
|
positive regulation of transcription regulatory region dna binding
|
GO:2000679 |
8 |
0.038
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.037
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.037
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.036
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.036
|
Human |
|
|
histone modification
|
GO:0016570 |
251 |
0.036
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.035
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.035
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.035
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.034
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.034
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.034
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.034
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.034
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.033
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.033
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.033
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.033
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.033
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.032
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.032
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
13 |
0.032
|
|
|
|
regulation of interferon alpha biosynthetic process
|
GO:0045354 |
4 |
0.031
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.031
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.031
|
|
|
|
endothelial cell development
|
GO:0001885 |
18 |
0.031
|
|
|
|
regulation of interleukin 4 biosynthetic process
|
GO:0045402 |
2 |
0.030
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.030
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.030
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.030
|
|
|
|
regulation of cd40 signaling pathway
|
GO:2000348 |
3 |
0.030
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.030
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.030
|
Human |
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.030
|
|
|
|
tolerance induction
|
GO:0002507 |
6 |
0.029
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.029
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.029
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.029
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.029
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.029
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.028
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.028
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.028
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.028
|
Human |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.027
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.027
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.027
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.027
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.027
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.026
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.026
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
18 |
0.026
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.026
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.026
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.025
|
|
|
|
regulation of immunoglobulin secretion
|
GO:0051023 |
1 |
0.025
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.025
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.025
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.025
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.025
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.024
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.024
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.024
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.024
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.024
|
|
|
|
positive regulation of type i interferon production
|
GO:0032481 |
20 |
0.024
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.024
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.024
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.024
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.024
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.024
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.024
|
|
|
|
positive regulation of interferon alpha biosynthetic process
|
GO:0045356 |
4 |
0.024
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.023
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.023
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.023
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.023
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.023
|
Human |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.023
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.022
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.022
|
|
|
|
skeletal muscle contraction
|
GO:0003009 |
16 |
0.022
|
|
|
|
regulation of interleukin 13 biosynthetic process
|
GO:0045366 |
1 |
0.022
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.022
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.022
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.022
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.022
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.021
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.021
|
|
|
|
detection of triacyl bacterial lipopeptide
|
GO:0042495 |
2 |
0.021
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.021
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.021
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.021
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.021
|
|
|
|
regulation of macrophage cytokine production
|
GO:0010935 |
4 |
0.021
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.021
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.021
|
Rat |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.020
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.020
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.020
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.020
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.020
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.020
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.020
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.020
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.019
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
63 |
0.019
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.019
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.019
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
23 |
0.019
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.019
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.019
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.019
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
29 |
0.019
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.019
|
|
|
|
nucleotide binding domain leucine rich repeat containing receptor signaling pathway
|
GO:0035872 |
5 |
0.019
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.019
|
|
|
|
regulation of mrna stability
|
GO:0043488 |
23 |
0.019
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.018
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.018
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.018
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.018
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.018
|
|
|
|
regulation of rna stability
|
GO:0043487 |
23 |
0.018
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.018
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.018
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.018
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.018
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.018
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.018
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.018
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.018
|
|
