Homo sapiens

170 known processes

IRAK3

interleukin-1 receptor-associated kinase 3

(Aliases: IRAKM,ASRT5,FLJ13601)

IRAK3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to bacterial lipoprotein GO:0071220 3 0.926
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.924
toll like receptor 2 signaling pathway GO:0034134 4 0.916
Human
regulation of tumor necrosis factor production GO:0032680 43 0.908
cytokine production GO:0001816 247 0.870
tumor necrosis factor production GO:0032640 43 0.849
negative regulation of tumor necrosis factor production GO:0032720 20 0.813
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 4 0.800
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.773
interleukin 17 production GO:0032620 12 0.730
positive regulation of toll like receptor signaling pathway GO:0034123 10 0.724
response to cytokine GO:0034097 232 0.705
cellular response to biotic stimulus GO:0071216 71 0.648
Human
response to peptidoglycan GO:0032494 3 0.611
Mouse
response to other organism GO:0051707 261 0.582
Human Mouse
cellular response to triacyl bacterial lipopeptide GO:0071727 2 0.539
growth of symbiont in host GO:0044117 1 0.504
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.503
negative regulation of growth of symbiont involved in interaction with host GO:0044146 2 0.477
cellular response to lipid GO:0071396 127 0.453
Human
response to bacterium GO:0009617 144 0.411
Human Mouse
response to lipoteichoic acid GO:0070391 3 0.409
cellular response to molecule of bacterial origin GO:0071219 62 0.408
Human
activation of immune response GO:0002253 114 0.400
Human Mouse
positive regulation of cytokine production GO:0001819 167 0.399
response to external biotic stimulus GO:0043207 261 0.392
Human Mouse
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.391
response to triacyl bacterial lipopeptide GO:0071725 2 0.379
detection of diacyl bacterial lipopeptide GO:0042496 2 0.373
regulation of chemokine biosynthetic process GO:0045073 4 0.337
interleukin 6 production GO:0032635 37 0.330
response to lipid GO:0033993 206 0.327
Human Mouse
response to lipopolysaccharide GO:0032496 70 0.326
Human Mouse
response to oxygen containing compound GO:1901700 369 0.322
Human Mouse
pattern recognition receptor signaling pathway GO:0002221 48 0.322
Human Mouse
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.319
positive regulation of phosphorylation GO:0042327 394 0.307
Human
immune response GO:0006955 307 0.306
Human Mouse
detection of bacterial lipoprotein GO:0042494 3 0.294
positive regulation of tumor necrosis factor production GO:0032760 21 0.288
defense response GO:0006952 315 0.276
Human Mouse
response to molecule of bacterial origin GO:0002237 82 0.268
Human Mouse
immune response activating signal transduction GO:0002757 90 0.257
Human Mouse
response to biotic stimulus GO:0009607 276 0.255
Human Mouse
positive regulation of immune response GO:0050778 159 0.246
Human Mouse
regulation of cytokine production GO:0001817 232 0.238
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.238
negative regulation of tumor necrosis factor superfamily cytokine production GO:1903556 20 0.237
toll like receptor 4 signaling pathway GO:0034142 12 0.235
regulation of protein transport GO:0051223 213 0.228
regulation of interleukin 17 production GO:0032660 12 0.211
positive regulation of immune system process GO:0002684 283 0.211
Human Mouse
mapk cascade GO:0000165 288 0.211
regulation of innate immune response GO:0045088 97 0.208
Human Mouse
positive regulation of interleukin 17 production GO:0032740 8 0.199
positive regulation of jnk cascade GO:0046330 52 0.195
response to diacyl bacterial lipopeptide GO:0071724 2 0.189
innate immune response activating signal transduction GO:0002758 48 0.183
Human Mouse
i kappab phosphorylation GO:0007252 7 0.178
positive regulation of mapk cascade GO:0043410 190 0.173
response to abiotic stimulus GO:0009628 336 0.171
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.164
Human
regulation of cell motility GO:2000145 299 0.156
response to interleukin 1 GO:0070555 47 0.156
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.155
activation of innate immune response GO:0002218 55 0.154
Human Mouse
positive regulation of map kinase activity GO:0043406 80 0.152
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.149
Human
innate immune response GO:0045087 178 0.149
Human Mouse
cellular response to lipopolysaccharide GO:0071222 57 0.146
Human
interferon alpha biosynthetic process GO:0045349 4 0.132
nucleotide binding oligomerization domain containing signaling pathway GO:0070423 4 0.131
negative regulation of multicellular organismal process GO:0051241 317 0.130
negative regulation of protein phosphorylation GO:0001933 140 0.128
positive regulation of transferase activity GO:0051347 227 0.128
Human
positive regulation of innate immune response GO:0045089 79 0.126
Human Mouse
cellular response to bacterial lipopeptide GO:0071221 3 0.125
regulation of response to external stimulus GO:0032101 222 0.122
nucleotide catabolic process GO:0009166 408 0.122
growth involved in symbiotic interaction GO:0044110 2 0.121
regulation of protein secretion GO:0050708 86 0.121
jnk cascade GO:0007254 80 0.119
modulation of growth of symbiont involved in interaction with host GO:0044144 2 0.119
guanosine containing compound metabolic process GO:1901068 244 0.116
positive regulation of protein kinase activity GO:0045860 190 0.115
Human
positive regulation of protein secretion GO:0050714 60 0.114
regulation of interleukin 12 production GO:0032655 15 0.113
regulation of kinase activity GO:0043549 314 0.113
negative regulation of protein metabolic process GO:0051248 391 0.112
chemokine biosynthetic process GO:0042033 4 0.111
negative regulation of cellular protein metabolic process GO:0032269 353 0.111
positive regulation of stress activated mapk cascade GO:0032874 60 0.111
cellular response to oxygen containing compound GO:1901701 276 0.107
Human
ribonucleoside catabolic process GO:0042454 406 0.107
positive regulation of toll like receptor 4 signaling pathway GO:0034145 6 0.105
positive regulation of protein phosphorylation GO:0001934 313 0.100
Human
cell activation GO:0001775 213 0.097
growth of symbiont involved in interaction with host GO:0044116 2 0.096
regulation of protein localization GO:0032880 296 0.096
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.095
cellular response to diacyl bacterial lipopeptide GO:0071726 2 0.095
purine ribonucleotide catabolic process GO:0009154 404 0.094
cytokine mediated signaling pathway GO:0019221 109 0.093
response to bacterial lipoprotein GO:0032493 3 0.093
cellular amine metabolic process GO:0044106 41 0.090
negative regulation of interleukin 12 production GO:0032695 6 0.088
chemokine metabolic process GO:0050755 4 0.088
i kappab kinase nf kappab signaling GO:0007249 166 0.087
Human
negative regulation of catalytic activity GO:0043086 335 0.086
purine nucleoside triphosphate catabolic process GO:0009146 392 0.086
regulation of lipopolysaccharide mediated signaling pathway GO:0031664 13 0.085
positive regulation of leukocyte proliferation GO:0070665 48 0.085
inflammatory response GO:0006954 79 0.084
regulation of secretion GO:0051046 194 0.083
nucleoside phosphate catabolic process GO:1901292 412 0.083
detection of bacterial lipopeptide GO:0070340 3 0.082
protein catabolic process GO:0030163 325 0.081
regulation of establishment of protein localization GO:0070201 242 0.081
negative regulation of cholesterol transport GO:0032375 8 0.080
negative regulation of phosphorus metabolic process GO:0010563 267 0.078
positive regulation of cell motility GO:2000147 177 0.078
positive regulation of apoptotic process GO:0043065 246 0.076
activation of protein kinase activity GO:0032147 90 0.075
Human
cytokine secretion GO:0050663 64 0.075
regulation of nucleotide metabolic process GO:0006140 269 0.074
regulation of interleukin 6 production GO:0032675 37 0.072
positive regulation of cell proliferation GO:0008284 301 0.072
ras protein signal transduction GO:0007265 73 0.072
stress activated mapk cascade GO:0051403 93 0.070
toll like receptor signaling pathway GO:0002224 25 0.070
Human Mouse
positive regulation of cellular catabolic process GO:0031331 284 0.069
positive regulation of interleukin 8 production GO:0032757 36 0.069
regulation of nucleoside metabolic process GO:0009118 209 0.069
interleukin 12 production GO:0032615 15 0.069
regulation of vesicle mediated transport GO:0060627 130 0.068
positive regulation of cell differentiation GO:0045597 211 0.067
signal transduction by phosphorylation GO:0023014 297 0.067
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.065
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.065
protein oligomerization GO:0051259 173 0.065
Human
purine nucleotide catabolic process GO:0006195 405 0.065
purine ribonucleoside catabolic process GO:0046130 398 0.063
positive regulation of transport GO:0051050 336 0.063
detection of triacyl bacterial lipopeptide GO:0042495 2 0.061
regulation of protein serine threonine kinase activity GO:0071900 179 0.061
regulation of cellular amino acid metabolic process GO:0006521 6 0.061
positive regulation of toll like receptor 2 signaling pathway GO:0034137 2 0.061
regulation of interferon alpha biosynthetic process GO:0045354 4 0.060
negative regulation of protein modification process GO:0031400 200 0.060
regulation of cellular amine metabolic process GO:0033238 11 0.059
immune response regulating signaling pathway GO:0002764 97 0.059
Human Mouse
purine containing compound catabolic process GO:0072523 411 0.059
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.058
Human
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.058
regulation of purine nucleotide metabolic process GO:1900542 264 0.058
vesicle mediated transport GO:0016192 371 0.058
positive regulation of secretion by cell GO:1903532 108 0.058
negative regulation of phosphate metabolic process GO:0045936 267 0.058
positive regulation of chemokine production GO:0032722 22 0.057
secretion by cell GO:0032940 226 0.057
nucleoside triphosphate metabolic process GO:0009141 422 0.056
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.056
negative regulation of cytokine production GO:0001818 82 0.055
defense response to bacterium GO:0042742 63 0.055
regulation of cell activation GO:0050865 125 0.054
gtp metabolic process GO:0046039 239 0.054
secretion GO:0046903 254 0.053
nucleoside catabolic process GO:0009164 408 0.052
ribonucleoside triphosphate metabolic process GO:0009199 412 0.052
positive regulation of jun kinase activity GO:0043507 23 0.051
response to magnesium ion GO:0032026 3 0.051
purine ribonucleoside metabolic process GO:0046128 437 0.051
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.051
positive regulation of cytokine biosynthetic process GO:0042108 25 0.051
amine metabolic process GO:0009308 44 0.050
regulation of transferase activity GO:0051338 355 0.050
regulation of immune response GO:0050776 201 0.049
Human Mouse
nucleoside triphosphate catabolic process GO:0009143 394 0.049
positive regulation of interferon beta biosynthetic process GO:0045359 4 0.048
negative regulation of intracellular signal transduction GO:1902532 183 0.048
gtp catabolic process GO:0006184 237 0.048
positive regulation of toll like receptor 3 signaling pathway GO:0034141 1 0.047
regulation of mapk cascade GO:0043408 262 0.046
vasculature development GO:0001944 181 0.046
ribonucleotide catabolic process GO:0009261 405 0.046
regulation of cellular response to stress GO:0080135 244 0.045
regulation of leukocyte migration GO:0002685 63 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.045
response to bacterial lipopeptide GO:0070339 3 0.045
negative regulation of protein catabolic process GO:0042177 59 0.044
regulation of jun kinase activity GO:0043506 27 0.044
cell adhesion GO:0007155 325 0.044
response to organonitrogen compound GO:0010243 156 0.043
Mouse
regulation of jnk cascade GO:0046328 73 0.042
purine nucleoside catabolic process GO:0006152 398 0.042
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.041
Human
post embryonic development GO:0009791 2 0.041
positive regulation of defense response GO:0031349 87 0.041
Human Mouse
activation of nf kappab inducing kinase activity GO:0007250 9 0.040
Human
negative regulation of phosphorylation GO:0042326 174 0.040
regulation of protein kinase activity GO:0045859 289 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.038
cellular ketone metabolic process GO:0042180 80 0.038
type i interferon production GO:0032606 27 0.038
lymphocyte activation GO:0046649 133 0.038
cardiovascular system development GO:0072358 262 0.038
response to tumor necrosis factor GO:0034612 76 0.037
positive regulation of nucleoside metabolic process GO:0045979 186 0.037
interleukin 1 mediated signaling pathway GO:0070498 12 0.037
cellular response to lipoteichoic acid GO:0071223 3 0.037
positive regulation of nucleotide catabolic process GO:0030813 185 0.036
multicellular organismal aging GO:0010259 3 0.036
smooth muscle cell proliferation GO:0048659 28 0.036
sterol transport GO:0015918 39 0.036
organophosphate catabolic process GO:0046434 430 0.036
cdc42 protein signal transduction GO:0032488 4 0.036
endocytosis GO:0006897 159 0.036
regulation of locomotion GO:0040012 329 0.035
lipid localization GO:0010876 106 0.035
regulation of response to wounding GO:1903034 101 0.035
negative regulation of mapk cascade GO:0043409 56 0.035
macromolecular complex disassembly GO:0032984 60 0.034
positive regulation of nucleotide metabolic process GO:0045981 230 0.034
regulation of endocytosis GO:0030100 72 0.033
regulation of toll like receptor 2 signaling pathway GO:0034135 2 0.033
positive regulation of interferon alpha biosynthetic process GO:0045356 4 0.033
interleukin 8 production GO:0032637 51 0.033
anatomical structure formation involved in morphogenesis GO:0048646 284 0.033
cellular response to cytokine stimulus GO:0071345 181 0.033
positive regulation of cellular component organization GO:0051130 376 0.032
myeloid cell differentiation GO:0030099 117 0.032
response to fungus GO:0009620 4 0.032
lipid transport GO:0006869 90 0.032
cellular response to decreased oxygen levels GO:0036294 51 0.032
regulation of interleukin 12 biosynthetic process GO:0045075 1 0.031
chemokine production GO:0032602 32 0.031
g protein coupled receptor signaling pathway GO:0007186 207 0.031
wnt signaling pathway GO:0016055 156 0.031
cytoplasmic transport GO:0016482 379 0.030
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.030
response to inorganic substance GO:0010035 127 0.030
ribonucleoside triphosphate catabolic process GO:0009203 391 0.030
negative regulation of protein complex disassembly GO:0043242 20 0.030
morphogenesis of embryonic epithelium GO:0016331 4 0.030
regulation of growth GO:0040008 165 0.029
primary neural tube formation GO:0014020 3 0.029
positive regulation of lymphocyte activation GO:0051251 73 0.029
cellular amino acid metabolic process GO:0006520 116 0.029
small gtpase mediated signal transduction GO:0007264 78 0.029
reactive oxygen species biosynthetic process GO:1903409 4 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.028
cellular component disassembly GO:0022411 92 0.028
positive regulation of catabolic process GO:0009896 310 0.028
negative regulation of growth GO:0045926 97 0.028
regulation of cellular ketone metabolic process GO:0010565 50 0.028
oxidation reduction process GO:0055114 396 0.028
regulation of interferon beta biosynthetic process GO:0045357 4 0.028
negative regulation of catabolic process GO:0009895 104 0.028
peptidyl tyrosine modification GO:0018212 170 0.027
regulation of purine nucleotide catabolic process GO:0033121 205 0.027
detection of external biotic stimulus GO:0098581 19 0.027
regulation of reactive oxygen species metabolic process GO:2000377 41 0.027
response to metal ion GO:0010038 84 0.027
protein complex disassembly GO:0043241 52 0.027
neural tube formation GO:0001841 3 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
response to organic cyclic compound GO:0014070 204 0.027
Mouse
regulation of gtpase activity GO:0043087 180 0.027
regulation of nucleotide catabolic process GO:0030811 205 0.027
regeneration GO:0031099 4 0.027
negative regulation of cellular component organization GO:0051129 235 0.026
negative regulation of neurological system process GO:0031645 2 0.026
positive regulation of secretion GO:0051047 116 0.026
cellular response to dna damage stimulus GO:0006974 379 0.026
regulation of inflammatory response GO:0050727 46 0.026
fatty acid metabolic process GO:0006631 115 0.026
regulation of cellular component movement GO:0051270 334 0.026
detection of molecule of bacterial origin GO:0032490 10 0.026
regulation of interferon beta production GO:0032648 22 0.026
endothelial cell development GO:0001885 18 0.025
female gamete generation GO:0007292 2 0.025
epithelial cell differentiation GO:0030855 141 0.025
regulation of nik nf kappab signaling GO:1901222 11 0.025
Human
cellular ion homeostasis GO:0006873 168 0.025
positive regulation of humoral immune response GO:0002922 3 0.025
negative regulation of immune system process GO:0002683 136 0.025
Mouse
positive regulation of smooth muscle cell proliferation GO:0048661 14 0.025
positive regulation of mononuclear cell proliferation GO:0032946 47 0.025
positive regulation of programmed cell death GO:0043068 249 0.025
cell growth GO:0016049 160 0.025
regulation of secretion by cell GO:1903530 177 0.024
regulation of growth of symbiont in host GO:0044126 1 0.024
negative regulation of cholesterol efflux GO:0090370 2 0.024
response to nitrogen compound GO:1901698 184 0.024
Mouse
regulation of gtp catabolic process GO:0033124 180 0.024
reactive nitrogen species metabolic process GO:2001057 3 0.024
positive regulation of nik nf kappab signaling GO:1901224 10 0.024
Human
regulation of cell cycle GO:0051726 393 0.024
positive regulation of cytokine secretion GO:0050715 42 0.024
negative regulation of cell cycle GO:0045786 193 0.023
intracellular protein transport GO:0006886 270 0.023
immune effector process GO:0002252 159 0.023
Mouse
regulation of cell cycle process GO:0010564 266 0.023
regulation of erk1 and erk2 cascade GO:0070372 99 0.023
response to heat GO:0009408 21 0.023
glycosyl compound catabolic process GO:1901658 413 0.023
regulation of mononuclear cell proliferation GO:0032944 65 0.023
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.023
leukocyte migration GO:0050900 107 0.023
positive regulation of gtpase activity GO:0043547 166 0.022
positive regulation of gtp catabolic process GO:0033126 166 0.022
regulation of ras gtpase activity GO:0032318 128 0.022
protein autophosphorylation GO:0046777 123 0.022
Human Mouse
protein maturation GO:0051604 233 0.022
negative regulation of transport GO:0051051 176 0.022
regulation of cytokine mediated signaling pathway GO:0001959 41 0.022
Human
immune system development GO:0002520 195 0.022
Mouse
regulation of cytokine biosynthetic process GO:0042035 35 0.021
reactive oxygen species metabolic process GO:0072593 75 0.021
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.021
blood vessel development GO:0001568 172 0.021
epithelium development GO:0060429 227 0.021
positive regulation of kinase activity GO:0033674 204 0.021
Human
positive regulation of hydrolase activity GO:0051345 331 0.021
apoptotic signaling pathway GO:0097190 268 0.020
regulation of vasculature development GO:1901342 97 0.020
cardiac muscle cell contraction GO:0086003 4 0.020
negative regulation of transferase activity GO:0051348 124 0.020
neuromuscular junction development GO:0007528 3 0.020
leukocyte activation GO:0045321 164 0.020
regulation of leukocyte proliferation GO:0070663 67 0.020
interspecies interaction between organisms GO:0044419 156 0.020
regulation of immunoglobulin production GO:0002637 4 0.020
oogenesis GO:0048477 2 0.019
response to hypoxia GO:0001666 96 0.019
cellular response to abiotic stimulus GO:0071214 117 0.019
positive regulation of interleukin 6 production GO:0032755 21 0.019
regulation of response to cytokine stimulus GO:0060759 46 0.019
Human
cellular component morphogenesis GO:0032989 314 0.019
cellular protein catabolic process GO:0044257 261 0.019
cellular lipid metabolic process GO:0044255 303 0.019
hindbrain development GO:0030902 3 0.019
positive regulation of endocytosis GO:0045807 42 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
toll signaling pathway GO:0008063 2 0.019
guanosine containing compound catabolic process GO:1901069 239 0.019
positive regulation of cellular component movement GO:0051272 181 0.019
cellular chemical homeostasis GO:0055082 180 0.019
cellular response to growth factor stimulus GO:0071363 197 0.018
positive regulation of behavior GO:0048520 60 0.018
positive regulation of ras gtpase activity GO:0032320 117 0.018
organic hydroxy compound transport GO:0015850 63 0.018
negative regulation of multi organism process GO:0043901 92 0.018
positive regulation of antimicrobial humoral response GO:0002760 1 0.018
regulation of map kinase activity GO:0043405 108 0.018
angiogenesis GO:0001525 147 0.018
neural tube closure GO:0001843 3 0.018
response to alcohol GO:0097305 64 0.018
tube closure GO:0060606 3 0.018
positive regulation of protein binding GO:0032092 24 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
positive regulation of cell migration GO:0030335 172 0.018
positive regulation of intracellular transport GO:0032388 104 0.018
regulation of binding GO:0051098 111 0.018
cell morphogenesis GO:0000902 296 0.018
regulation of cell adhesion GO:0030155 166 0.017
regulation of protein maturation GO:1903317 150 0.017
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.017
monocarboxylic acid metabolic process GO:0032787 185 0.017
protein targeting GO:0006605 187 0.017
response to oxygen levels GO:0070482 100 0.017
neuroblast proliferation GO:0007405 4 0.017
regulation of ras protein signal transduction GO:0046578 155 0.017
response to axon injury GO:0048678 1 0.017
cellular cation homeostasis GO:0030003 163 0.017
positive regulation of developmental process GO:0051094 314 0.017
Mouse
stem cell division GO:0017145 2 0.017
positive regulation of chemotaxis GO:0050921 57 0.017
response to ethanol GO:0045471 11 0.017
defense response to fungus GO:0050832 4 0.017
regulation of multi organism process GO:0043900 157 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
protein homooligomerization GO:0051260 100 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.016
positive regulation of transcription factor import into nucleus GO:0042993 25 0.016
regulation of stress activated mapk cascade GO:0032872 84 0.016
intracellular receptor signaling pathway GO:0030522 104 0.016
organic anion transport GO:0015711 103 0.016
positive regulation of locomotion GO:0040017 186 0.016
icosanoid metabolic process GO:0006690 35 0.016
negative regulation of interleukin 6 production GO:0032715 13 0.016
chemical homeostasis GO:0048878 306 0.016
cation homeostasis GO:0055080 189 0.016
growth GO:0040007 202 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
regulation of response to biotic stimulus GO:0002831 55 0.015
regulation of autophagy GO:0010506 52 0.015
compound eye development GO:0048749 1 0.015
mitotic cell cycle GO:0000278 326 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
nitrogen compound transport GO:0071705 191 0.015
cell development GO:0048468 328 0.015
negative regulation of cell differentiation GO:0045596 171 0.015
nervous system development GO:0007399 293 0.015
determination of adult lifespan GO:0008340 2 0.015
muscle system process GO:0003012 81 0.015
positive regulation of apoptotic signaling pathway GO:2001235 70 0.015
regulation of protein complex disassembly GO:0043244 28 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
nucleotide binding oligomerization domain containing 2 signaling pathway GO:0070431 4 0.014
metencephalon development GO:0022037 2 0.014
chromatin organization GO:0006325 351 0.014
locomotory behavior GO:0007626 1 0.014
mhc class ii biosynthetic process GO:0045342 4 0.014
defense response to virus GO:0051607 71 0.014
cell cycle phase transition GO:0044770 173 0.014
positive regulation of immune effector process GO:0002699 40 0.014
detection of lipopolysaccharide GO:0032497 3 0.014
response to decreased oxygen levels GO:0036293 96 0.014
cation transmembrane transport GO:0098655 238 0.014
cytokine biosynthetic process GO:0042089 37 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
single organism cellular localization GO:1902580 332 0.014
neurological system process GO:0050877 163 0.014
immunoglobulin secretion GO:0048305 1 0.014
somatic stem cell division GO:0048103 1 0.013
negative regulation of proteolysis GO:0045861 132 0.013
response to wounding GO:0009611 168 0.013
regulation of intracellular transport GO:0032386 195 0.013
cellular response to radiation GO:0071478 65 0.013
cation transport GO:0006812 331 0.013
regulation of cell growth GO:0001558 135 0.013
muscle cell proliferation GO:0033002 35 0.013
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
regulation of lipid transport GO:0032368 44 0.013
positive regulation of cellular amine metabolic process GO:0033240 7 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
regulation of viral process GO:0050792 103 0.013
maintenance of location GO:0051235 112 0.013
negative regulation of protein processing GO:0010955 142 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
cellular response to mechanical stimulus GO:0071260 39 0.013
purine nucleotide biosynthetic process GO:0006164 84 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
negative regulation of cell death GO:0060548 345 0.013
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.013
rho protein signal transduction GO:0007266 26 0.013
protein modification by small protein conjugation GO:0032446 342 0.013
aging GO:0007568 66 0.012
regulation of cell migration GO:0030334 289 0.012
neurotransmitter secretion GO:0007269 4 0.012
negative regulation of lipid transport GO:0032369 18 0.012
spermatid differentiation GO:0048515 4 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
positive regulation of wnt signaling pathway GO:0030177 54 0.012
response to radiation GO:0009314 151 0.012
positive regulation of response to biotic stimulus GO:0002833 18 0.012
nuclear transport GO:0051169 179 0.012
protein localization to organelle GO:0033365 280 0.012
nerve development GO:0021675 4 0.012
protein import into nucleus GO:0006606 104 0.012
spermatid development GO:0007286 4 0.012
protein ubiquitination GO:0016567 314 0.012
cell matrix adhesion GO:0007160 85 0.012
protein secretion GO:0009306 98 0.012
segmentation GO:0035282 4 0.012
erk1 and erk2 cascade GO:0070371 104 0.012
negative regulation of map kinase activity GO:0043407 27 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.012
positive regulation of cell death GO:0010942 263 0.012
endomembrane system organization GO:0010256 196 0.012
regulation of nucleocytoplasmic transport GO:0046822 98 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
mitotic cell cycle process GO:1903047 286 0.012
regulation of peptidase activity GO:0052547 180 0.012
antimicrobial humoral response GO:0019730 26 0.012

IRAK3 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.099
disease of cellular proliferation DOID:14566 174 0.099
organ system cancer DOID:0050686 164 0.073
eye disease DOID:5614 149 0.055
sensory system disease DOID:0050155 203 0.055
eye and adnexa disease DOID:1492 150 0.055
retinal disease DOID:5679 118 0.055
nervous system disease DOID:863 431 0.055
disease of metabolism DOID:0014667 295 0.050
inherited metabolic disorder DOID:655 242 0.028
musculoskeletal system disease DOID:17 223 0.024
disease of mental health DOID:150 70 0.017
retinal degeneration DOID:8466 89 0.015
neurodegenerative disease DOID:1289 102 0.013
central nervous system disease DOID:331 186 0.013