|
|
defense response
|
GO:0006952 |
315 |
0.950
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.895
|
Mouse |
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.839
|
Mouse |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.836
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.834
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.834
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.828
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
247 |
0.824
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.812
|
Mouse |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.811
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.768
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.701
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.690
|
Mouse |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.688
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.656
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.625
|
Mouse |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.620
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.607
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.603
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.601
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.593
|
Human Mouse |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.579
|
Mouse |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.569
|
Human |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.554
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.541
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.512
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.499
|
Human Mouse |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.495
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.491
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.485
|
Human |
|
|
positive regulation of interferon beta production
|
GO:0032728 |
17 |
0.469
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.460
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.434
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.422
|
Mouse |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.411
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.402
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.400
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.373
|
|
|
|
positive regulation of interleukin 13 biosynthetic process
|
GO:0045368 |
1 |
0.370
|
Human |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.365
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.358
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.355
|
|
|
|
positive regulation of interleukin 13 production
|
GO:0032736 |
4 |
0.351
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.348
|
Human |
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.347
|
|
|
|
regulation of type i interferon production
|
GO:0032479 |
26 |
0.322
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.320
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.320
|
|
|
|
negative regulation of calcium ion import
|
GO:0090281 |
1 |
0.314
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.310
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.302
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.295
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.290
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.279
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.276
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.274
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.270
|
Human |
|
|
response to muramyl dipeptide
|
GO:0032495 |
4 |
0.265
|
Human |
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.265
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.255
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.254
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.248
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.247
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.243
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.223
|
Human |
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.220
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.217
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.214
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.212
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.207
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.205
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.204
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.198
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.193
|
|
|
|
response to interferon gamma
|
GO:0034341 |
39 |
0.191
|
Mouse |
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
26 |
0.180
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.177
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.176
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.176
|
Human |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.172
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.172
|
|
|
|
regulation of interferon alpha production
|
GO:0032647 |
11 |
0.171
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.171
|
Human |
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.169
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.165
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.165
|
|
|
|
positive regulation of type i interferon production
|
GO:0032481 |
20 |
0.165
|
|
|
|
cellular response to interferon beta
|
GO:0035458 |
6 |
0.155
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.155
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.151
|
Mouse |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.140
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.138
|
Human |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.138
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.136
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.130
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.129
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.128
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.127
|
|
|
|
response to peptidoglycan
|
GO:0032494 |
3 |
0.125
|
Human |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.122
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.122
|
Mouse |
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
2 |
0.122
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.114
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.112
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.109
|
Mouse |
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.108
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.108
|
|
|
|
response to interferon beta
|
GO:0035456 |
11 |
0.106
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.105
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.096
|
|
|
|
interferon beta production
|
GO:0032608 |
23 |
0.096
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.095
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.095
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.094
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.093
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.093
|
Mouse |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.091
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.089
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.085
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.084
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.082
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.082
|
Mouse |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.082
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.080
|
Mouse |
|
|
cellular response to interferon gamma
|
GO:0071346 |
24 |
0.078
|
Mouse |
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.076
|
|
|
|
detection of chemical stimulus involved in sensory perception
|
GO:0050907 |
33 |
0.076
|
|
|
|
positive regulation of interleukin 4 biosynthetic process
|
GO:0045404 |
1 |
0.074
|
Human |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.074
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.074
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.073
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.070
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.069
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.069
|
Mouse |
|
|
regulation of interleukin 2 production
|
GO:0032663 |
19 |
0.069
|
Human |
|
|
nk t cell proliferation
|
GO:0001866 |
3 |
0.069
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.068
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.066
|
Mouse |
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.065
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.064
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.064
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.064
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.064
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.062
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.061
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.061
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.061
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.061
|
|
|
|
regulation of interferon beta production
|
GO:0032648 |
22 |
0.060
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.060
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.060
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.060
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.059
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.058
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.057
|
Human Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.056
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.056
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.056
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.056
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.053
|
Mouse |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.053
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.053
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.053
|
Mouse |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.052
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.052
|
|
|
|
regulation of interleukin 4 biosynthetic process
|
GO:0045402 |
2 |
0.051
|
Human |
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.051
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.050
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
23 |
0.050
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.050
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.050
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.050
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.050
|
|
|
|
interleukin 4 biosynthetic process
|
GO:0042097 |
2 |
0.049
|
Human |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.049
|
Mouse |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.049
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.048
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.048
|
Mouse |
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.048
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.047
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.046
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.045
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.044
|
|
|
|
interleukin 13 production
|
GO:0032616 |
7 |
0.044
|
Human |
|
|
innate immune response
|
GO:0045087 |
178 |
0.044
|
Mouse |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.043
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.043
|
Mouse |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.043
|
|
|
|
antigen processing and presentation via mhc class ib
|
GO:0002475 |
3 |
0.043
|
|
|
|
natural killer cell activation
|
GO:0030101 |
12 |
0.042
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
11 |
0.042
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.041
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.041
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.041
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.041
|
Mouse |
|
|
protein processing
|
GO:0016485 |
226 |
0.040
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.040
|
|
|
|
type i interferon biosynthetic process
|
GO:0045351 |
4 |
0.039
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.039
|
Human Mouse |
|
|
detection of chemical stimulus
|
GO:0009593 |
55 |
0.039
|
|
|
|
interleukin 2 production
|
GO:0032623 |
20 |
0.039
|
Human |
|
|
cell activation
|
GO:0001775 |
213 |
0.039
|
Mouse |
|
|
response to radiation
|
GO:0009314 |
151 |
0.039
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.039
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.039
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.038
|
Mouse |
|
|
cell development
|
GO:0048468 |
328 |
0.038
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.037
|
Mouse |
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.037
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
33 |
0.037
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.037
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.037
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.036
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.036
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.036
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.036
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.035
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.035
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.035
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.035
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.035
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.035
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.035
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.034
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.034
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.034
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.034
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.034
|
|
|
|
sensory perception of bitter taste
|
GO:0050913 |
28 |
0.034
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.033
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.033
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.033
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.033
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.032
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.032
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.032
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.032
|
Mouse |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.032
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.031
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.031
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.031
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.031
|
Mouse |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.031
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.031
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.030
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.030
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.030
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.030
|
Mouse |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.030
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.029
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.029
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.029
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.029
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.029
|
Mouse |
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.029
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.029
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.028
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.028
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.028
|
|
|
|
negative regulation of necrotic cell death
|
GO:0060547 |
3 |
0.028
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.028
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.028
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.027
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.027
|
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.027
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.027
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.026
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.026
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.026
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.026
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.026
|
|
|
|
interleukin 10 biosynthetic process
|
GO:0042091 |
2 |
0.026
|
Human |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.026
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
29 |
0.026
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
16 |
0.025
|
Human |
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
2 |
0.025
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.025
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.025
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.025
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.025
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.025
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.024
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.024
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.024
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.024
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.024
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.024
|
|
|
|
receptor mediated virion attachment to host cell
|
GO:0046813 |
4 |
0.024
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.024
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.024
|
|
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.024
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.023
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.023
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.023
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.023
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.023
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.023
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.023
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.023
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.023
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.023
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.023
|
|
|
|
adhesion of symbiont to host
|
GO:0044406 |
8 |
0.022
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.022
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.022
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.022
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.022
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.022
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.022
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.022
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.022
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.022
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.022
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.022
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.022
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.021
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.021
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.021
|
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.021
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.021
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.021
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.020
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.020
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.020
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.020
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.020
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.020
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.020
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.020
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.020
|
Human Mouse |
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.020
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.020
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.020
|
|
|
|
interleukin 6 mediated signaling pathway
|
GO:0070102 |
7 |
0.019
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.019
|
|
|
|
cd8 positive alpha beta t cell activation
|
GO:0036037 |
3 |
0.019
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.019
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.019
|
Mouse |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.019
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902042 |
15 |
0.019
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.019
|
|
|
|
translation
|
GO:0006412 |
132 |
0.019
|
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.019
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.019
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.018
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.018
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.018
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.018
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.018
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.018
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.018
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.018
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
13 |
0.018
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.018
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
27 |
0.018
|
|
|
|
positive regulation of natural killer cell proliferation
|
GO:0032819 |
3 |
0.017
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.017
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.017
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.017
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.017
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.017
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.017
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.017
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.017
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.017
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.017
|
|
|
|
negative regulation of mhc class ii biosynthetic process
|
GO:0045347 |
1 |
0.016
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.016
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
23 |
0.016
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.016
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.016
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.016
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.016
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.016
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.016
|
|
|
|
regulation of dendritic cell differentiation
|
GO:2001198 |
3 |
0.016
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
21 |
0.016
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.016
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
12 |
0.015
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.015
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
19 |
0.015
|
Mouse |
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.015
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.015
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.015
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.015
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.015
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.015
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.015
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.015
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.015
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.015
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.014
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.014
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.014
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.014
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.014
|
|
|
|
vasodilation
|
GO:0042311 |
4 |
0.014
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.014
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.014
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.014
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.014
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.014
|
|
|
|
negative regulation of reactive oxygen species biosynthetic process
|
GO:1903427 |
1 |
0.014
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
22 |
0.014
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.013
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.013
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.013
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.013
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.013
|
|
|
|
amide biosynthetic process
|
GO:0043604 |
15 |
0.013
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
3 |
0.013
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.013
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.013
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.013
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.013
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.013
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.013
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.013
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
24 |
0.013
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
12 |
0.013
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
15 |
0.013
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.013
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.013
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.013
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.013
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.013
|
|
|
|
interleukin 10 production
|
GO:0032613 |
17 |
0.013
|
Human |
|
|
transition metal ion transport
|
GO:0000041 |
23 |
0.013
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.012
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.012
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.012
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.012
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.012
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.012
|
Human Mouse |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.012
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.012
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.012
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.012
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.012
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.012
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.012
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.012
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.012
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.012
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
18 |
0.012
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.012
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
23 |
0.012
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.012
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.011
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
16 |
0.011
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.011
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.011
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.011
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
38 |
0.011
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
21 |
0.011
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.011
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.011
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.011
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.011
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.011
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.011
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
25 |
0.011
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.011
|
|
|
|
cellular response to muramyl dipeptide
|
GO:0071225 |
3 |
0.011
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.011
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
31 |
0.011
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.011
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.011
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.011
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.011
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.011
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
18 |
0.011
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.010
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.010
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.010
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
14 |
0.010
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.010
|
|
|
|
growth
|
GO:0040007 |
202 |
0.010
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.010
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.010
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.010
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.010
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.010
|
|
