|
|
skin development
|
GO:0043588 |
76 |
0.936
|
Human |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.929
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.923
|
Mouse |
|
|
membrane organization
|
GO:0061024 |
292 |
0.900
|
Human Worm |
|
|
epithelium development
|
GO:0060429 |
227 |
0.872
|
Human Fly |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.866
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.858
|
Mouse |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.854
|
Mouse Worm |
|
|
tube development
|
GO:0035295 |
125 |
0.843
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.842
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.838
|
Human |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.823
|
Human Zebrafish Fly |
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.818
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.809
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.807
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.794
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.789
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.785
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.774
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.771
|
Human |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.769
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.760
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.748
|
Human |
|
|
sensory perception of smell
|
GO:0007608 |
2 |
0.738
|
Fly |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.710
|
Human |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.709
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.702
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.689
|
|
|
|
negative regulation of low density lipoprotein particle receptor biosynthetic process
|
GO:0045715 |
3 |
0.688
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.684
|
|
|
|
regulation of lipoprotein metabolic process
|
GO:0050746 |
7 |
0.674
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.674
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.671
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.644
|
Human |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.640
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.632
|
Human |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.626
|
Fly |
|
|
wound healing
|
GO:0042060 |
115 |
0.614
|
Human |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.592
|
Human |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.592
|
Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.575
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.574
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.560
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.555
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.547
|
Human Worm |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.534
|
Human |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.526
|
Human |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.525
|
Fly |
|
|
lipid transport
|
GO:0006869 |
90 |
0.502
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.501
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.500
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.490
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.482
|
Worm Fly |
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.470
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
0.469
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.464
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.441
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.440
|
Human |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.427
|
Human Fly |
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.416
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.414
|
Fly |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.402
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.400
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.397
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.397
|
Mouse |
|
|
response to wounding
|
GO:0009611 |
168 |
0.395
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.390
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.385
|
Worm |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.381
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.380
|
Human |
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.366
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.363
|
Fly |
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.363
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.355
|
Fly |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.351
|
Human |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.347
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.343
|
Fly |
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
27 |
0.343
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.327
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.320
|
|
|
|
system process
|
GO:0003008 |
349 |
0.318
|
Human Worm Fly |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.316
|
Human |
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.303
|
Human |
|
|
cardiac right ventricle morphogenesis
|
GO:0003215 |
3 |
0.301
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.301
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.298
|
|
|
|
positive regulation of keratinocyte migration
|
GO:0051549 |
4 |
0.297
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.296
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.294
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
10 |
0.290
|
Human |
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.284
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.277
|
|
|
|
regulation of multicellular organismal metabolic process
|
GO:0044246 |
17 |
0.274
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.274
|
Human |
|
|
regulation of keratinocyte migration
|
GO:0051547 |
4 |
0.271
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.264
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.261
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.260
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.259
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.257
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.253
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.252
|
Fly |
|
|
gastrulation
|
GO:0007369 |
51 |
0.249
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.247
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.245
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.243
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.238
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.238
|
Fly |
|
|
blood coagulation
|
GO:0007596 |
76 |
0.232
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.226
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.225
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.223
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.220
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.218
|
Human |
|
|
cell matrix adhesion involved in ameboidal cell migration
|
GO:0003366 |
2 |
0.215
|
Human |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.212
|
Human |
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.210
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.210
|
Fly |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.209
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.208
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.207
|
Fly |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.206
|
|
|
|
keratinocyte migration
|
GO:0051546 |
6 |
0.205
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.205
|
Fly |
|
|
regulation of nitric oxide mediated signal transduction
|
GO:0010749 |
2 |
0.198
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.198
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.196
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.193
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.185
|
Fly |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.183
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.181
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.181
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.178
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.176
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.175
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.173
|
Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.173
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.171
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.169
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.169
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.168
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.168
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.165
|
|
|
|
wound healing spreading of cells
|
GO:0044319 |
8 |
0.164
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.164
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.163
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.163
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.163
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.161
|
Human |
|
|
nervous system development
|
GO:0007399 |
293 |
0.160
|
Fly |
|
|
negative regulation of lipid transport
|
GO:0032369 |
18 |
0.160
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.154
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.154
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.153
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.153
|
|
|
|
negative regulation of nitric oxide mediated signal transduction
|
GO:0010751 |
2 |
0.149
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.149
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.148
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.147
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.146
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.145
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.145
|
Human |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.144
|
|
|
|
epithelial cell cell adhesion
|
GO:0090136 |
7 |
0.143
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.142
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.141
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.140
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.138
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.138
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.137
|
Fly |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.137
|
Fly |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.137
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.136
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.136
|
Mouse |
|
|
digestive tract development
|
GO:0048565 |
75 |
0.135
|
|
|
|
growth
|
GO:0040007 |
202 |
0.134
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.134
|
Fly |
|
|
limb development
|
GO:0060173 |
23 |
0.134
|
Human |
|
|
multicellular organismal macromolecule metabolic process
|
GO:0044259 |
29 |
0.133
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.133
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.132
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.132
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.129
|
Human |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.129
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.128
|
|
|
|
epiboly involved in wound healing
|
GO:0090505 |
8 |
0.125
|
Human |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.124
|
Fly |
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.123
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.123
|
Human |
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.122
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.121
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.121
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.119
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.116
|
Human |
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.115
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.113
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.112
|
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
38 |
0.112
|
Fly |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.112
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.109
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.108
|
Human |
|
|
digestive system development
|
GO:0055123 |
75 |
0.108
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.107
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.107
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.106
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.104
|
|
|
|
negative regulation of plasminogen activation
|
GO:0010757 |
4 |
0.103
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.102
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.101
|
Human |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.101
|
Fly |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.100
|
Fly |
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.099
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.097
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.097
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.096
|
|
|
|
phospholipid translocation
|
GO:0045332 |
2 |
0.095
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.095
|
|
|
|
entry into other organism involved in symbiotic interaction
|
GO:0051828 |
25 |
0.095
|
|
|
|
negative regulation of endothelial cell chemotaxis
|
GO:2001027 |
4 |
0.094
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.094
|
Human |
|
|
organic anion transport
|
GO:0015711 |
103 |
0.094
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.091
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.091
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.090
|
|
|
|
entry into host
|
GO:0044409 |
25 |
0.090
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.089
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.089
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.089
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.087
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.087
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.087
|
Fly |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.086
|
|
|
|
regulation of collagen catabolic process
|
GO:0010710 |
3 |
0.085
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.084
|
Fly |
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.082
|
|
|
|
collagen metabolic process
|
GO:0032963 |
28 |
0.081
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.078
|
|
|
|
anion transmembrane transport
|
GO:0098656 |
76 |
0.077
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.077
|
|
|
|
positive regulation of fibroblast migration
|
GO:0010763 |
3 |
0.077
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.075
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.075
|
Human |
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.075
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.074
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.074
|
Worm |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.074
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.073
|
Human |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.073
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.072
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.072
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.072
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.072
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.072
|
|
|
|
pharyngeal system development
|
GO:0060037 |
2 |
0.071
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.071
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.071
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
44 |
0.071
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.071
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.070
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.070
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.070
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.069
|
|
|
|
neutrophil migration
|
GO:1990266 |
25 |
0.068
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.067
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.067
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.067
|
Fly |
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.066
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.065
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.065
|
Fly |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.065
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.063
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.063
|
Worm |
|
|
neural crest cell migration
|
GO:0001755 |
2 |
0.062
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.061
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.061
|
Fly |
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.061
|
|
|
|
cardiac muscle cell fate commitment
|
GO:0060923 |
4 |
0.060
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.060
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.060
|
|
|
|
lipid translocation
|
GO:0034204 |
2 |
0.059
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.059
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.058
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.057
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.057
|
|
|
|
regulation of collagen metabolic process
|
GO:0010712 |
15 |
0.057
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.057
|
|
|
|
cell cell adhesion via plasma membrane adhesion molecules
|
GO:0098742 |
19 |
0.057
|
|
|
|
response to manganese ion
|
GO:0010042 |
2 |
0.056
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.055
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.055
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.055
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.054
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.054
|
Fly |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.054
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.054
|
|
|
|
movement in environment of other organism involved in symbiotic interaction
|
GO:0052192 |
25 |
0.054
|
|
|
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.053
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.053
|
Fly |
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.052
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.051
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.051
|
|
|
|
regulation of t cell chemotaxis
|
GO:0010819 |
7 |
0.051
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.051
|
Human |
|
|
macrophage fusion
|
GO:0034238 |
1 |
0.051
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.051
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.051
|
Human |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.050
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.050
|
Worm |
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.049
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.049
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.049
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.049
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.048
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.048
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.048
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.047
|
|
|
|
distal tubule development
|
GO:0072017 |
4 |
0.047
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.047
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.047
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.046
|
|
|
|
cellular extravasation
|
GO:0045123 |
21 |
0.046
|
Human |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.045
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.045
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.045
|
|
|
|
odontogenesis
|
GO:0042476 |
25 |
0.045
|
Human |
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.044
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.044
|
|
|
|
movement in host environment
|
GO:0052126 |
25 |
0.044
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.044
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.044
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.044
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.044
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.044
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.043
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.043
|
|
|
|
elastic fiber assembly
|
GO:0048251 |
3 |
0.043
|
|
|
|
dendritic cell antigen processing and presentation
|
GO:0002468 |
1 |
0.043
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.043
|
|
|
|
appendage development
|
GO:0048736 |
23 |
0.043
|
Human Fly |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.043
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.042
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.042
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.042
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.042
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.042
|
Fly |
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.042
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.042
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.041
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.041
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.041
|
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.041
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.041
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.041
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.041
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.040
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.040
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.040
|
Human |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.040
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.040
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.039
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.039
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.039
|
|
|
|
regulation of lymphocyte chemotaxis
|
GO:1901623 |
12 |
0.039
|
|
|
|
negative regulation of trophoblast cell migration
|
GO:1901164 |
3 |
0.039
|
|
|
|
loop of henle development
|
GO:0072070 |
2 |
0.039
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.038
|
|
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.038
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.038
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.038
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.038
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.038
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.038
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.038
|
|
|
|
receptor transactivation
|
GO:0035624 |
4 |
0.038
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.037
|
Fly |
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.037
|
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.037
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.037
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.037
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.037
|
Human |
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.037
|
Fly |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.036
|
Fly |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.036
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.036
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.036
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.036
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.036
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.036
|
|
|
|
calcium independent cell matrix adhesion
|
GO:0007161 |
1 |
0.035
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.035
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.035
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.035
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
26 |
0.034
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.034
|
Human |
|
|
positive regulation of hemostasis
|
GO:1900048 |
11 |
0.034
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.034
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.034
|
|
|
|
endocardial cell differentiation
|
GO:0060956 |
2 |
0.034
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.034
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.034
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.034
|
|
|
|
transition metal ion transport
|
GO:0000041 |
23 |
0.033
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.033
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.033
|
Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.033
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.033
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.033
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.033
|
Worm |
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.033
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.033
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.033
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.032
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.032
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.032
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.032
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.032
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.032
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.032
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.031
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.031
|
Mouse |
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.031
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.031
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.031
|
Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.031
|
Fly |
|
|
cell cell adhesion mediated by integrin
|
GO:0033631 |
8 |
0.031
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.031
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.031
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.031
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.030
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.030
|
Worm |
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.030
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.030
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.030
|
Human |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.030
|
|
|
|
positive regulation of phagocytosis engulfment
|
GO:0060100 |
1 |
0.030
|
Worm |
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.030
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.030
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.029
|
|
|
|
mesoderm formation
|
GO:0001707 |
10 |
0.029
|
Human |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.029
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.029
|
Worm |
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
16 |
0.029
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.029
|
|
|
|
chondrocyte proliferation
|
GO:0035988 |
4 |
0.029
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.029
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.029
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.029
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.029
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.028
|
|
|
|
negative chemotaxis
|
GO:0050919 |
11 |
0.028
|
|
|
|
memory
|
GO:0007613 |
3 |
0.028
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.028
|
|
|
|
chronic inflammatory response
|
GO:0002544 |
2 |
0.028
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.028
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.028
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.028
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.028
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.027
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.027
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.027
|
|
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
22 |
0.027
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.027
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.027
|
Worm |
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.027
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.027
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.027
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.027
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.027
|
|
|
|
entry into cell of other organism involved in symbiotic interaction
|
GO:0051806 |
25 |
0.027
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.027
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.027
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.026
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.026
|
Human |
|
|
regulation of anoikis
|
GO:2000209 |
19 |
0.026
|
Human |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.026
|
|
|
|
negative regulation of fibroblast growth factor receptor signaling pathway
|
GO:0040037 |
2 |
0.026
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.026
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.026
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.026
|
|
|
|
lymphocyte migration
|
GO:0072676 |
28 |
0.026
|
|