Homo sapiens

133 known processes

JAG1

jagged 1

(Aliases: HJ1,AHD,MGC104644,AWS,CD339,JAGL1,AGS)

JAG1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aortic valve development GO:0003176 3 1.000
negative regulation of endothelial cell chemotaxis GO:2001027 4 1.000
cell fate commitment involved in pattern specification GO:0060581 1 1.000
Human
aortic valve morphogenesis GO:0003180 3 1.000
mitral valve development GO:0003174 3 1.000
cardiac cell fate specification GO:0060912 1 1.000
cardiac right ventricle morphogenesis GO:0003215 3 1.000
Mouse
positive regulation of cell fate specification GO:0042660 2 1.000
atrial septum morphogenesis GO:0060413 5 1.000
regulation of cardioblast differentiation GO:0051890 4 1.000
mitral valve morphogenesis GO:0003183 2 1.000
regulation of cell migration involved in sprouting angiogenesis GO:0090049 9 1.000
Human
atrioventricular valve development GO:0003171 3 1.000
i kappab phosphorylation GO:0007252 7 1.000
notch signaling involved in heart development GO:0061314 2 1.000
negative regulation of cell migration involved in sprouting angiogenesis GO:0090051 6 1.000
Human
cardiac atrium morphogenesis GO:0003209 7 1.000
cell migration involved in sprouting angiogenesis GO:0002042 19 1.000
Human
neuronal stem cell maintenance GO:0097150 5 1.000
cardiac atrium development GO:0003230 10 1.000
neuron fate commitment GO:0048663 2 1.000
Human
ventricular septum morphogenesis GO:0060412 3 1.000
muscle cell fate commitment GO:0042693 4 1.000
atrioventricular valve morphogenesis GO:0003181 2 1.000
cardioblast cell fate commitment GO:0042684 1 1.000
cellular response to gonadotropin stimulus GO:0071371 4 1.000
organ formation GO:0048645 3 1.000
heart valve morphogenesis GO:0003179 8 1.000
sprouting angiogenesis GO:0002040 29 1.000
Human
glial cell migration GO:0008347 4 1.000
cardioblast cell fate specification GO:0042685 1 1.000
atrial septum development GO:0003283 8 1.000
regulation of cardioblast cell fate specification GO:0042686 1 1.000
atrioventricular valve formation GO:0003190 1 1.000
regulation of epithelial cell migration GO:0010632 93 1.000
Human
regulation of cardiac cell fate specification GO:2000043 1 0.999
cardiac septum morphogenesis GO:0060411 9 0.999
Mouse
pulmonary valve morphogenesis GO:0003184 5 0.999
spinal cord development GO:0021510 4 0.999
Human
cardiac right ventricle formation GO:0003219 1 0.999
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003256 3 0.999
pulmonary valve development GO:0003177 5 0.999
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.999
cardiac chamber morphogenesis GO:0003206 26 0.999
Mouse
mesenchymal cell development GO:0014031 50 0.999
Mouse
motor neuron axon guidance GO:0008045 2 0.999
cardiac ventricle formation GO:0003211 2 0.999
cell differentiation in spinal cord GO:0021515 1 0.998
Human
hair cell differentiation GO:0035315 2 0.998
Zebrafish Mouse Rat
heart valve formation GO:0003188 2 0.998
negative regulation of muscle cell differentiation GO:0051148 17 0.997
regulation of muscle cell differentiation GO:0051147 31 0.997
negative regulation of epithelial cell migration GO:0010633 38 0.997
Human
negative regulation of myoblast differentiation GO:0045662 7 0.996
epithelium migration GO:0090132 119 0.996
Human
glomerulus vasculature development GO:0072012 6 0.995
hindbrain development GO:0030902 3 0.995
blood vessel development GO:0001568 172 0.995
regulation of endothelial cell migration GO:0010594 67 0.995
Human
mesodermal cell fate specification GO:0007501 2 0.995
kidney vasculature development GO:0061440 7 0.995
cell fate determination GO:0001709 3 0.994
blood vessel endothelial cell migration GO:0043534 42 0.994
Human
long term memory GO:0007616 2 0.994
regulation of striated muscle cell differentiation GO:0051153 25 0.994
glomerulus development GO:0032835 15 0.994
endothelial cell migration GO:0043542 86 0.994
Human
regulation of chemotaxis GO:0050920 74 0.993
mitral valve formation GO:0003192 1 0.993
regulation of myoblast differentiation GO:0045661 12 0.993
blood vessel morphogenesis GO:0048514 162 0.992
negative regulation of cell migration GO:0030336 102 0.992
Human
regulation of striated muscle tissue development GO:0016202 26 0.992
circulatory system development GO:0072359 262 0.992
cardiac septum development GO:0003279 13 0.991
Mouse
urogenital system development GO:0001655 65 0.990
Mouse
cardiocyte differentiation GO:0035051 23 0.990
Mouse
negative regulation of locomotion GO:0040013 118 0.990
Human
mesenchymal cell differentiation GO:0048762 52 0.990
Mouse
cardiac chamber formation GO:0003207 2 0.990
renal tubule development GO:0061326 19 0.990
Mouse
regulation of muscle organ development GO:0048634 27 0.989
cell chemotaxis GO:0060326 112 0.989
endothelial cell chemotaxis GO:0035767 13 0.989
endocardial cushion development GO:0003197 3 0.988
Mouse
somatic stem cell maintenance GO:0035019 4 0.988
distal tubule development GO:0072017 4 0.988
Mouse
epithelium development GO:0060429 227 0.987
Zebrafish Mouse Rat
heart valve development GO:0003170 8 0.987
regulation of muscle tissue development GO:1901861 26 0.987
regulation of behavior GO:0050795 82 0.987
positive regulation of cell proliferation GO:0008284 301 0.987
mesenchyme development GO:0060485 59 0.987
Mouse
regulation of endodermal cell fate specification GO:0042663 1 0.986
angiogenesis GO:0001525 147 0.985
Human
tissue migration GO:0090130 119 0.985
Human
epithelial cell fate commitment GO:0072148 3 0.984
mesodermal cell fate commitment GO:0001710 2 0.984
epithelial cell migration GO:0010631 119 0.984
Human
memory GO:0007613 3 0.984
nephron epithelium development GO:0072009 23 0.984
Mouse
positive regulation of notch signaling pathway GO:0045747 6 0.984
Mouse
cardiac vascular smooth muscle cell differentiation GO:0060947 2 0.983
skeletal muscle fiber development GO:0048741 12 0.981
cardiac cell fate commitment GO:0060911 7 0.981
negative regulation of multicellular organismal process GO:0051241 317 0.981
Human Mouse
vasculature development GO:0001944 181 0.980
nephron development GO:0072006 30 0.979
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.979
Human
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.979
kidney epithelium development GO:0072073 25 0.979
Mouse
tube morphogenesis GO:0035239 95 0.978
Zebrafish
digestive tract development GO:0048565 75 0.977
small gtpase mediated signal transduction GO:0007264 78 0.975
hair follicle morphogenesis GO:0031069 2 0.975
regeneration GO:0031099 4 0.974
Rat
positive regulation of cardiac muscle cell proliferation GO:0060045 2 0.972
ras protein signal transduction GO:0007265 73 0.971
vascular smooth muscle cell development GO:0097084 1 0.971
regulation of cell differentiation GO:0045595 393 0.971
kidney development GO:0001822 53 0.970
Mouse
negative regulation of developmental process GO:0051093 247 0.970
regulation of locomotion GO:0040012 329 0.970
Human
tissue regeneration GO:0042246 3 0.969
regulation of stem cell differentiation GO:2000736 56 0.969
morphogenesis of an epithelium GO:0002009 60 0.968
Mouse
peripheral nervous system development GO:0007422 2 0.968
tissue morphogenesis GO:0048729 96 0.967
Mouse
negative regulation of cell motility GO:2000146 104 0.967
Human
ameboidal type cell migration GO:0001667 135 0.967
Human
organ morphogenesis GO:0009887 147 0.966
Zebrafish Mouse Fly
embryonic hemopoiesis GO:0035162 4 0.963
stem cell development GO:0048864 69 0.963
cell proliferation in forebrain GO:0021846 1 0.963
digestive system development GO:0055123 75 0.962
ventricular septum development GO:0003281 5 0.962
cardiovascular system development GO:0072358 262 0.961
regulation of epithelial to mesenchymal transition GO:0010717 37 0.961
heart formation GO:0060914 2 0.960
regulation of cell migration GO:0030334 289 0.960
Human
positive regulation of stem cell differentiation GO:2000738 29 0.959
heart morphogenesis GO:0003007 48 0.959
Mouse
cell adhesion GO:0007155 325 0.958
positive regulation of epithelial to mesenchymal transition GO:0010718 22 0.957
response to growth factor GO:0070848 205 0.957
Human
regulation of blood vessel endothelial cell migration GO:0043535 30 0.956
Human
negative regulation of cell adhesion GO:0007162 64 0.956
oligodendrocyte development GO:0014003 6 0.955
positive regulation of developmental process GO:0051094 314 0.954
Mouse
regulation of cell adhesion GO:0030155 166 0.953
regulation of endothelial cell chemotaxis GO:2001026 9 0.953
negative regulation of cell substrate adhesion GO:0010812 24 0.953
negative regulation of angiogenesis GO:0016525 39 0.952
Human
biological adhesion GO:0022610 331 0.952
ventricular trabecula myocardium morphogenesis GO:0003222 1 0.951
embryonic morphogenesis GO:0048598 85 0.951
Zebrafish
epithelial to mesenchymal transition GO:0001837 48 0.948
regulation of cellular component movement GO:0051270 334 0.947
Human
tube development GO:0035295 125 0.946
Zebrafish Mouse
regulation of anatomical structure morphogenesis GO:0022603 286 0.944
Human
regulation of endothelial cell differentiation GO:0045601 4 0.944
negative regulation of cellular component movement GO:0051271 106 0.944
Human
regulation of myotube differentiation GO:0010830 18 0.942
female gamete generation GO:0007292 2 0.939
formation of primary germ layer GO:0001704 42 0.937
oogenesis GO:0048477 2 0.936
embryonic heart tube morphogenesis GO:0003143 8 0.935
positive regulation of cell cycle GO:0045787 140 0.934
negative regulation of blood vessel endothelial cell migration GO:0043537 16 0.933
Human
prostate gland morphogenesis GO:0060512 1 0.933
regulation of cell fate commitment GO:0010453 7 0.929
cellular response to vascular endothelial growth factor stimulus GO:0035924 26 0.929
Human
regulation of cellular component biogenesis GO:0044087 281 0.928
cardiac ventricle development GO:0003231 23 0.928
Mouse
negative regulation of stem cell differentiation GO:2000737 22 0.927
proximal tubule development GO:0072014 1 0.925
myoblast differentiation GO:0045445 21 0.925
cell development GO:0048468 328 0.924
muscle tissue development GO:0060537 62 0.920
regulation of cell motility GO:2000145 299 0.914
Human
regulation of vasculature development GO:1901342 97 0.912
Human
muscle structure development GO:0061061 98 0.912
cell substrate adhesion GO:0031589 132 0.911
negative regulation of cell proliferation GO:0008285 228 0.911
Human
regulation of smooth muscle cell proliferation GO:0048660 28 0.910
morphogenesis of an epithelial sheet GO:0002011 12 0.909
Mouse
stem cell maintenance GO:0019827 19 0.907
regulation of astrocyte differentiation GO:0048710 3 0.904
i kappab kinase nf kappab signaling GO:0007249 166 0.903
negative regulation of cell development GO:0010721 48 0.903
Mouse
stem cell differentiation GO:0048863 93 0.902
hair follicle maturation GO:0048820 3 0.901
muscle cell proliferation GO:0033002 35 0.901
regulation of cell cycle g1 s phase transition GO:1902806 42 0.899
cellular response to endogenous stimulus GO:0071495 336 0.899
Human
cardiac epithelial to mesenchymal transition GO:0060317 3 0.898
endocardium development GO:0003157 2 0.897
positive regulation of bmp signaling pathway GO:0030513 9 0.896
regulation of cell fate specification GO:0042659 5 0.896
notch signaling pathway GO:0007219 31 0.895
regulation of cardiac muscle tissue development GO:0055024 13 0.895
epidermis morphogenesis GO:0048730 3 0.894
negative regulation of vasculature development GO:1901343 43 0.893
Human
regulation of cell substrate adhesion GO:0010810 68 0.889
actin filament based process GO:0030029 224 0.888
endodermal cell fate commitment GO:0001711 4 0.887
mitotic cell cycle phase transition GO:0044772 162 0.884
negative regulation of cell differentiation GO:0045596 171 0.881
cardiac conduction system development GO:0003161 2 0.881
negative regulation of gliogenesis GO:0014014 3 0.880
cellular response to growth factor stimulus GO:0071363 197 0.879
Human
positive regulation of mesoderm development GO:2000382 2 0.878
striated muscle cell differentiation GO:0051146 43 0.877
muscle organ development GO:0007517 56 0.875
regulation of cell cycle process GO:0010564 266 0.864
regulation of bmp signaling pathway GO:0030510 27 0.862
post embryonic development GO:0009791 2 0.858
Fly
negative regulation of programmed cell death GO:0043069 321 0.857
mesoderm development GO:0007498 14 0.855
somatic stem cell division GO:0048103 1 0.855
actin filament organization GO:0007015 128 0.854
positive regulation of locomotion GO:0040017 186 0.853
g1 s transition of mitotic cell cycle GO:0000082 78 0.852
smooth muscle cell proliferation GO:0048659 28 0.852
gland development GO:0048732 48 0.851
Zebrafish Fly
oligodendrocyte differentiation GO:0048709 7 0.847
negative regulation of endothelial cell migration GO:0010596 29 0.845
Human
taxis GO:0042330 157 0.842
multicellular organismal aging GO:0010259 3 0.842
collecting duct development GO:0072044 2 0.841
neurological system process GO:0050877 163 0.839
epidermal cell differentiation GO:0009913 45 0.838
Zebrafish Mouse Rat
negative regulation of cell death GO:0060548 345 0.838
positive regulation of cell differentiation GO:0045597 211 0.837
Mouse
myeloid cell differentiation GO:0030099 117 0.835
Mouse
regulation of pro b cell differentiation GO:2000973 1 0.834
gastrulation GO:0007369 51 0.834
chemotaxis GO:0006935 157 0.834
regulation of response to external stimulus GO:0032101 222 0.831
endoderm formation GO:0001706 33 0.831
bmp signaling pathway GO:0030509 49 0.830
positive regulation of neural precursor cell proliferation GO:2000179 2 0.830
cardiac endothelial cell differentiation GO:0003348 2 0.829
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.829
pericardium development GO:0060039 2 0.828
leukocyte activation GO:0045321 164 0.828
Human
wound healing GO:0042060 115 0.823
muscle fiber development GO:0048747 16 0.822
positive regulation of mitotic cell cycle GO:0045931 60 0.821
regulation of skeletal muscle fiber development GO:0048742 12 0.818
cardioblast differentiation GO:0010002 8 0.817
response to biotic stimulus GO:0009607 276 0.816
muscle cell development GO:0055001 29 0.814
determination of adult lifespan GO:0008340 2 0.813
epidermis development GO:0008544 59 0.810
Zebrafish Mouse Rat
negative regulation of behavior GO:0048521 15 0.810
positive regulation of cell motility GO:2000147 177 0.809
cardiac chamber development GO:0003205 30 0.809
Mouse
actin cytoskeleton organization GO:0030036 207 0.808
epithelial tube morphogenesis GO:0060562 38 0.805
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.804
positive regulation of small gtpase mediated signal transduction GO:0051057 12 0.798
ventral spinal cord development GO:0021517 1 0.795
Human
system process GO:0003008 349 0.793
morphogenesis of a branching structure GO:0001763 21 0.793
epithelial cell differentiation GO:0030855 141 0.792
Zebrafish Mouse Rat
striated muscle tissue development GO:0014706 59 0.786
regulation of receptor mediated endocytosis GO:0048259 32 0.784
regulation of ras protein signal transduction GO:0046578 155 0.784
digestive tract morphogenesis GO:0048546 56 0.783
muscle cell differentiation GO:0042692 63 0.782
regulation of cell cycle GO:0051726 393 0.781
cell cycle g1 s phase transition GO:0044843 80 0.780
cell cell signaling GO:0007267 155 0.779
Fly
regulation of ossification GO:0030278 58 0.779
Mouse
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 19 0.778
cytokine production GO:0001816 247 0.777
Human
regulation of heart growth GO:0060420 4 0.776
negative regulation of apoptotic process GO:0043066 316 0.772
stem cell division GO:0017145 2 0.768
somitogenesis GO:0001756 2 0.767
neural crest cell development GO:0014032 3 0.766
Mouse
cardiac muscle cell myoblast differentiation GO:0060379 5 0.765
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.765
regulation of cell projection organization GO:0031344 107 0.765
tissue remodeling GO:0048771 16 0.763
Mouse
cell morphogenesis involved in differentiation GO:0000904 144 0.756
regulation of mesodermal cell fate specification GO:0042661 2 0.756
hemopoiesis GO:0030097 180 0.753
Human Mouse Fly
positive regulation of cell migration GO:0030335 172 0.747
nervous system development GO:0007399 293 0.747
Human Zebrafish Mouse Rat Fly
regulation of mitotic cell cycle GO:0007346 189 0.737
heart development GO:0007507 95 0.737
kidney vasculature morphogenesis GO:0061439 1 0.729
negative regulation of neurogenesis GO:0050768 26 0.728
Mouse
hematopoietic or lymphoid organ development GO:0048534 186 0.725
Human Mouse Fly
renal system vasculature morphogenesis GO:0061438 1 0.724
endodermal cell fate specification GO:0001714 4 0.722
astrocyte differentiation GO:0048708 4 0.719
regulation of cardiac muscle cell proliferation GO:0060043 4 0.714
regulation of heart morphogenesis GO:2000826 4 0.714
positive regulation of phosphorylation GO:0042327 394 0.711
endocardial cell differentiation GO:0060956 2 0.708
regulation of cell morphogenesis GO:0022604 153 0.707
epithelial cell proliferation GO:0050673 128 0.703
regulation of angiogenesis GO:0045765 92 0.699
Human
neuroblast proliferation GO:0007405 4 0.698
negative regulation of response to external stimulus GO:0032102 83 0.697
gland morphogenesis GO:0022612 8 0.689
Fly
regulation of epithelial cell proliferation GO:0050678 113 0.684
embryonic organ development GO:0048568 36 0.681
Zebrafish
cell fate specification GO:0001708 8 0.681
blood circulation GO:0008015 113 0.678
cell morphogenesis GO:0000902 296 0.677
renal system development GO:0072001 63 0.674
Mouse
growth GO:0040007 202 0.673
venous blood vessel development GO:0060841 2 0.669
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.668
mitotic cell cycle process GO:1903047 286 0.666
pattern specification process GO:0007389 43 0.666
Human Zebrafish Fly
cardiac muscle tissue development GO:0048738 39 0.665
amine metabolic process GO:0009308 44 0.664
behavior GO:0007610 112 0.664
negative regulation of neuron differentiation GO:0045665 21 0.661
Mouse
negative regulation of glial cell proliferation GO:0060253 2 0.657
regulation of gastrulation GO:0010470 12 0.656
positive regulation of cell development GO:0010720 92 0.653
positive regulation of apoptotic process GO:0043065 246 0.652
pro b cell differentiation GO:0002328 1 0.646
filopodium assembly GO:0046847 18 0.644
cell cycle phase transition GO:0044770 173 0.639
myotube cell development GO:0014904 14 0.636
left right pattern formation GO:0060972 2 0.635
positive regulation of cellular component organization GO:0051130 376 0.629
connective tissue development GO:0061448 39 0.628
Zebrafish
cell fate commitment GO:0045165 27 0.623
Human Fly
embryonic hindlimb morphogenesis GO:0035116 2 0.623
appendage development GO:0048736 23 0.621
Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.620
positive regulation of cardiac muscle tissue growth GO:0055023 2 0.618
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.615
neuron projection development GO:0031175 106 0.609
negative regulation of glial cell differentiation GO:0045686 1 0.606
mesangial cell development GO:0072143 1 0.606
hindlimb morphogenesis GO:0035137 2 0.606
cellular component morphogenesis GO:0032989 314 0.605
positive regulation of epithelial cell proliferation GO:0050679 65 0.602
regulation of skeletal muscle tissue development GO:0048641 15 0.602
regulation of mitotic cell cycle phase transition GO:1901990 118 0.601
mitotic cell cycle GO:0000278 326 0.601
Fly
hepaticobiliary system development GO:0061008 10 0.601
Zebrafish
negative regulation of bmp signaling pathway GO:0030514 17 0.600
osteoblast differentiation GO:0001649 92 0.599
Mouse
salivary gland morphogenesis GO:0007435 4 0.599
Fly
neuron differentiation GO:0030182 138 0.597
Human Zebrafish Mouse Rat
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.596
regulation of osteoblast differentiation GO:0045667 38 0.593
Mouse
negative regulation of transport GO:0051051 176 0.592
positive regulation of neuroblast proliferation GO:0002052 2 0.590
cell surface receptor signaling pathway involved in heart development GO:0061311 8 0.589
epithelial cell development GO:0002064 34 0.588
Zebrafish
cell projection organization GO:0030030 252 0.587
cell projection assembly GO:0030031 126 0.582
response to hormone GO:0009725 175 0.581
renal interstitial fibroblast development GO:0072141 1 0.576
positive regulation of gliogenesis GO:0014015 4 0.576
mesodermal cell differentiation GO:0048333 10 0.569
embryonic appendage morphogenesis GO:0035113 9 0.563
response to gonadotropin GO:0034698 5 0.562
endodermal cell differentiation GO:0035987 31 0.556
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.554
trabecula morphogenesis GO:0061383 2 0.550
renal filtration cell differentiation GO:0061318 4 0.544
limb morphogenesis GO:0035108 16 0.539
regulation of myeloid cell differentiation GO:0045637 81 0.538
Mouse
regulation of endodermal cell differentiation GO:1903224 3 0.538
embryonic organ morphogenesis GO:0048562 24 0.538
Zebrafish
response to lipid GO:0033993 206 0.536
limb development GO:0060173 23 0.535
response to external biotic stimulus GO:0043207 261 0.534
appendage morphogenesis GO:0035107 16 0.534
Fly
cell cell signaling involved in cell fate commitment GO:0045168 5 0.532
Fly
defense response GO:0006952 315 0.523
response to wounding GO:0009611 168 0.520
regulation of growth GO:0040008 165 0.519
regionalization GO:0003002 29 0.518
Human Zebrafish Fly
regulation of cell cycle phase transition GO:1901987 126 0.517
regulation of glial cell proliferation GO:0060251 4 0.511
regulation of cell development GO:0060284 161 0.510
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.508
regulation of vesicle mediated transport GO:0060627 130 0.506
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.506
Human
mammary gland development GO:0030879 17 0.503
skeletal muscle tissue development GO:0007519 24 0.502
cell projection morphogenesis GO:0048858 129 0.501
regulation of cellular amine metabolic process GO:0033238 11 0.498
regulation of organ formation GO:0003156 4 0.494
cellular amine metabolic process GO:0044106 41 0.494
vascular process in circulatory system GO:0003018 29 0.489
positive regulation of jak stat cascade GO:0046427 35 0.489
positive regulation of cell death GO:0010942 263 0.489
coronary vasculature development GO:0060976 2 0.486
positive regulation of protein phosphorylation GO:0001934 313 0.485
cell growth GO:0016049 160 0.485
positive regulation of programmed cell death GO:0043068 249 0.482
cellular amino acid metabolic process GO:0006520 116 0.480
compound eye development GO:0048749 1 0.476
Fly
bone remodeling GO:0046849 11 0.474
developmental growth GO:0048589 48 0.473
prostate gland development GO:0030850 3 0.471
venous blood vessel morphogenesis GO:0048845 1 0.471
positive regulation of smooth muscle cell proliferation GO:0048661 14 0.467
head development GO:0060322 108 0.467
Zebrafish
generation of neurons GO:0048699 152 0.467
Human Zebrafish Mouse Rat
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.464
chordate embryonic development GO:0043009 34 0.454
epithelial cell differentiation involved in kidney development GO:0035850 9 0.452
heart looping GO:0001947 7 0.452
positive regulation of organ growth GO:0046622 2 0.449
respiratory tube development GO:0030323 20 0.446
homeostasis of number of cells GO:0048872 40 0.446
regulation of epidermis development GO:0045682 19 0.444
negative regulation of chemotaxis GO:0050922 13 0.444
response to other organism GO:0051707 261 0.440
neural tube development GO:0021915 9 0.432
regulation of cardiac muscle tissue growth GO:0055021 4 0.432
cardiac muscle cell proliferation GO:0060038 6 0.430
regulation of cell proliferation involved in heart morphogenesis GO:2000136 1 0.430
lymphangiogenesis GO:0001946 7 0.429
forebrain development GO:0030900 26 0.426
negative regulation of myotube differentiation GO:0010832 4 0.425
negative regulation of secretion by cell GO:1903531 52 0.425
lymphocyte activation GO:0046649 133 0.423
Human
renal system vasculature development GO:0061437 7 0.422
immune response GO:0006955 307 0.422
leukocyte differentiation GO:0002521 98 0.421
Human
cellular response to hormone stimulus GO:0032870 125 0.417
immune system development GO:0002520 195 0.417
Human Mouse Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.414
regulation of anoikis GO:2000209 19 0.411
neurogenesis GO:0022008 169 0.409
Human Zebrafish Mouse Rat Fly
segmentation GO:0035282 4 0.409
Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.401
vascular smooth muscle cell differentiation GO:0035886 3 0.397
positive regulation of heart growth GO:0060421 2 0.397
positive regulation of cell fate commitment GO:0010455 2 0.396
striated muscle cell development GO:0055002 27 0.396
response to organic cyclic compound GO:0014070 204 0.392
regulation of filopodium assembly GO:0051489 13 0.386
artery morphogenesis GO:0048844 7 0.386
keratinocyte differentiation GO:0030216 36 0.385
tube formation GO:0035148 10 0.381
response to follicle stimulating hormone GO:0032354 2 0.381
apoptotic process involved in morphogenesis GO:0060561 3 0.381
branching morphogenesis of an epithelial tube GO:0048754 19 0.372
glial cell differentiation GO:0010001 11 0.371
regulation of meiotic cell cycle GO:0051445 4 0.365
regulation of neuroblast proliferation GO:1902692 3 0.364
myotube differentiation GO:0014902 22 0.362
negative regulation of nervous system development GO:0051961 28 0.358
Mouse
cardiac muscle cell fate commitment GO:0060923 4 0.357
negative regulation of cell cycle GO:0045786 193 0.357
ossification GO:0001503 121 0.355
Mouse
myeloid dendritic cell differentiation GO:0043011 3 0.350
t cell activation GO:0042110 99 0.350
Human
cardiac left ventricle morphogenesis GO:0003214 6 0.349
single organismal cell cell adhesion GO:0016337 148 0.348
glomerular mesangial cell differentiation GO:0072008 2 0.346
cell proliferation involved in heart morphogenesis GO:0061323 1 0.346
regulation of small gtpase mediated signal transduction GO:0051056 156 0.344
cell division GO:0051301 168 0.340
regulation of neural precursor cell proliferation GO:2000177 4 0.339
regulation of blood vessel size GO:0050880 18 0.338
developmental programmed cell death GO:0010623 3 0.337
circulatory system process GO:0003013 113 0.333
defense response to bacterium GO:0042742 63 0.326
lung development GO:0030324 20 0.325
regulation of cell projection assembly GO:0060491 47 0.323
neuron development GO:0048666 113 0.323
Zebrafish
lymph vessel development GO:0001945 9 0.321
glial cell development GO:0021782 7 0.315
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.315
embryo development GO:0009790 123 0.309
Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.309
regulation of glial cell differentiation GO:0045685 3 0.306
embryonic heart tube development GO:0035050 9 0.304
pronephros development GO:0048793 2 0.304
skeletal muscle organ development GO:0060538 26 0.301
cardiac muscle tissue morphogenesis GO:0055008 18 0.297
canonical wnt signaling pathway GO:0060070 116 0.296
hair cycle GO:0042633 28 0.296
regulation of endocytosis GO:0030100 72 0.295
secretion by cell GO:0032940 226 0.292

JAG1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 106 0.910
heart disease DOID:114 68 0.834
hepatobiliary disease DOID:3118 7 0.682
gastrointestinal system disease DOID:77 36 0.682
liver disease DOID:409 7 0.682