Homo sapiens

208 known processes

JUP

junction plakoglobin

(Aliases: DP3,ARVD12,CTNNG,DPIII,PDGB,PKGB)

JUP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cardiac muscle cell cardiac muscle cell adhesion GO:0086042 1 1.000
keratinization GO:0031424 2 1.000
cardiac muscle cell action potential involved in contraction GO:0086002 21 1.000
negative regulation of catagen GO:0051796 1 1.000
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.998
cardiac muscle cell action potential GO:0086001 23 0.998
cell communication involved in cardiac conduction GO:0086065 18 0.996
mesendoderm development GO:0048382 1 0.994
cardiac muscle cell contraction GO:0086003 4 0.994
positive regulation of keratinocyte proliferation GO:0010838 4 0.992
catagen GO:0042637 3 0.991
ventricular cardiac muscle cell action potential GO:0086005 15 0.989
regulation of cardiac muscle cell contraction GO:0086004 23 0.988
blood circulation GO:0008015 113 0.985
regulation of heart rate GO:0002027 38 0.984
negative regulation of cell proliferation GO:0008285 228 0.984
Human
regulation of actin filament based process GO:0032970 141 0.977
circulatory system process GO:0003013 113 0.974
protein localization to adherens junction GO:0071896 2 0.972
Fly
actin filament based movement GO:0030048 17 0.972
bundle of his cell to purkinje myocyte communication GO:0086069 8 0.962
cellular response to endogenous stimulus GO:0071495 336 0.953
regulation of melanosome transport GO:1902908 1 0.952
single organismal cell cell adhesion GO:0016337 148 0.950
multicellular organismal signaling GO:0035637 34 0.942
striated muscle contraction GO:0006941 52 0.933
cell junction organization GO:0034330 79 0.933
regulation of cellular component movement GO:0051270 334 0.926
system process GO:0003008 349 0.924
biological adhesion GO:0022610 331 0.921
low density lipoprotein particle mediated signaling GO:0055096 1 0.918
muscle contraction GO:0006936 73 0.918
regulation of heart contraction GO:0008016 50 0.917
desmosome assembly GO:0002159 4 0.916
heparan sulfate proteoglycan biosynthetic process GO:0015012 8 0.915
Human
actin filament based process GO:0030029 224 0.908
regulation of heart rate by cardiac conduction GO:0086091 19 0.905
protein localization to membrane GO:0072657 160 0.902
regulation of cell migration GO:0030334 289 0.901
Worm
cardiac muscle contraction GO:0060048 34 0.899
canonical wnt signaling pathway GO:0060070 116 0.872
Human Fly
regulation of actin filament based movement GO:1903115 24 0.870
cell cell junction organization GO:0045216 69 0.868
rho protein signal transduction GO:0007266 26 0.868
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.862
cardiac conduction GO:0061337 23 0.862
cardiovascular system development GO:0072358 262 0.861
Zebrafish Fly
positive regulation of ossification GO:0045778 32 0.858
negative regulation of epidermis development GO:0045683 5 0.846
regulation of blood circulation GO:1903522 59 0.845
actin mediated cell contraction GO:0070252 12 0.845
muscle system process GO:0003012 81 0.842
regulation of cardiac muscle contraction GO:0055117 33 0.831
regulation of system process GO:0044057 101 0.831
regulation of melanin biosynthetic process GO:0048021 1 0.825
response to oxygen containing compound GO:1901700 369 0.823
intermediate filament based process GO:0045103 17 0.821
regulation of cell differentiation GO:0045595 393 0.808
Human Worm Fly
regulation of cell motility GO:2000145 299 0.807
Worm
single organism cellular localization GO:1902580 332 0.806
positive regulation of osteoblast differentiation GO:0045669 23 0.805
action potential GO:0001508 34 0.800
secondary metabolite biosynthetic process GO:0044550 2 0.797
salivary gland morphogenesis GO:0007435 4 0.792
adherens junction organization GO:0034332 36 0.783
Human Fly
regulation of striated muscle contraction GO:0006942 37 0.775
regulation of smooth muscle cell proliferation GO:0048660 28 0.772
Human
regulation of membrane potential GO:0042391 95 0.770
lipoprotein particle mediated signaling GO:0055095 1 0.766
regulation of rho protein signal transduction GO:0035023 79 0.736
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.722
desmosome organization GO:0002934 5 0.716
skin development GO:0043588 76 0.696
Mouse
regulation of cell adhesion GO:0030155 166 0.691
Fly
regulation of muscle contraction GO:0006937 45 0.678
ribonucleotide catabolic process GO:0009261 405 0.669
hair follicle morphogenesis GO:0031069 2 0.669
cell fate determination GO:0001709 3 0.665
Worm Fly
glycosyl compound catabolic process GO:1901658 413 0.663
small gtpase mediated signal transduction GO:0007264 78 0.645
Worm
positive regulation of cell motility GO:2000147 177 0.630
cell substrate adhesion GO:0031589 132 0.624
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.619
pigment biosynthetic process GO:0046148 10 0.617
establishment of protein localization to membrane GO:0090150 121 0.617
regulation of protein localization GO:0032880 296 0.603
digestive tract development GO:0048565 75 0.602
Worm Fly
motor neuron axon guidance GO:0008045 2 0.602
epithelium development GO:0060429 227 0.597
Human Worm Fly
endomembrane system organization GO:0010256 196 0.596
negative regulation of interleukin 5 production GO:0032714 3 0.590
membrane organization GO:0061024 292 0.590
cerebral cortex radially oriented cell migration GO:0021799 1 0.584
cell migration involved in gastrulation GO:0042074 1 0.567
negative regulation of hair follicle maturation GO:0048817 1 0.549
nucleoside catabolic process GO:0009164 408 0.549
microtubule based process GO:0007017 210 0.544
Human Worm
negative regulation of stem cell proliferation GO:2000647 3 0.543
regulation of locomotion GO:0040012 329 0.538
Worm
cell junction assembly GO:0034329 67 0.535
positive regulation of cell cycle process GO:0090068 106 0.534
circulatory system development GO:0072359 262 0.530
Zebrafish Fly
heart process GO:0003015 62 0.524
negative regulation of binding GO:0051100 57 0.524
negative regulation of wnt signaling pathway GO:0030178 69 0.522
Zebrafish
neuroblast proliferation GO:0007405 4 0.508
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.483
single organism cell adhesion GO:0098602 179 0.479
organophosphate catabolic process GO:0046434 430 0.478
cell adhesion GO:0007155 325 0.474
tube development GO:0035295 125 0.469
Human Worm Fly
positive regulation of rho gtpase activity GO:0032321 56 0.469
segmentation GO:0035282 4 0.469
enzyme linked receptor protein signaling pathway GO:0007167 303 0.469
canonical wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition GO:0044334 2 0.463
Human
heart contraction GO:0060047 62 0.463
regulation of myeloid cell differentiation GO:0045637 81 0.462
proteoglycan metabolic process GO:0006029 29 0.456
Human
regulation of rho gtpase activity GO:0032319 66 0.433
pharynx development GO:0060465 1 0.432
Worm
cell activation GO:0001775 213 0.427
purine nucleoside catabolic process GO:0006152 398 0.426
wound healing GO:0042060 115 0.421
response to low density lipoprotein particle GO:0055098 4 0.421
taxis GO:0042330 157 0.419
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.417
wnt signaling pathway GO:0016055 156 0.415
Human Zebrafish Worm Fly
regulation of monophenol monooxygenase activity GO:0032771 1 0.414
regulation of neuron migration GO:2001222 3 0.400
positive regulation of cell division GO:0051781 59 0.399
epithelial cell differentiation GO:0030855 141 0.381
positive regulation of proteoglycan biosynthetic process GO:1902730 3 0.380
Human
keratinocyte differentiation GO:0030216 36 0.377
regulation of osteoblast differentiation GO:0045667 38 0.375
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.373
Human
apical junction assembly GO:0043297 19 0.367
Fly
plasma membrane organization GO:0007009 115 0.364
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.363
cell development GO:0048468 328 0.361
Human Fly
cellular response to oxygen containing compound GO:1901701 276 0.358
generation of neurons GO:0048699 152 0.354
Fly
regulation of ossification GO:0030278 58 0.351
negative regulation of transforming growth factor beta2 production GO:0032912 2 0.351
negative regulation of protein binding GO:0032091 35 0.350
pituitary gland development GO:0021983 2 0.345
cellular response to nitrogen compound GO:1901699 144 0.342
guanosine containing compound catabolic process GO:1901069 239 0.340
vasculature development GO:0001944 181 0.334
melanin metabolic process GO:0006582 1 0.328
ras protein signal transduction GO:0007265 73 0.326
Worm
cellular response to hormone stimulus GO:0032870 125 0.325
cardiac muscle tissue development GO:0048738 39 0.323
cerebral cortex cell migration GO:0021795 3 0.312
intermediate filament organization GO:0045109 10 0.312
epidermis development GO:0008544 59 0.312
response to organonitrogen compound GO:0010243 156 0.296
nephron tubule formation GO:0072079 1 0.293
purine ribonucleoside catabolic process GO:0046130 398 0.292
cell cell signaling GO:0007267 155 0.291
Fly
organic hydroxy compound metabolic process GO:1901615 147 0.290
oogenesis GO:0048477 2 0.290
Fly
positive regulation of cell adhesion GO:0045785 84 0.290
chemotaxis GO:0006935 157 0.289
cell matrix adhesion GO:0007160 85 0.288
pigment granule localization GO:0051875 7 0.288
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.285
cell cell junction assembly GO:0007043 25 0.282
positive regulation of locomotion GO:0040017 186 0.282
regulation of cytokinesis GO:0032465 45 0.282
single organism nuclear import GO:1902593 104 0.277
regulation of neuroblast proliferation GO:1902692 3 0.277
ventricular cardiac muscle tissue development GO:0003229 14 0.275
negative regulation of developmental process GO:0051093 247 0.274
Zebrafish Fly
epiboly involved in gastrulation with mouth forming second GO:0055113 1 0.270
keratinocyte proliferation GO:0043616 17 0.268
cellular response to lipoprotein particle stimulus GO:0071402 1 0.268
purine ribonucleoside metabolic process GO:0046128 437 0.267
nucleotide catabolic process GO:0009166 408 0.267
protein localization to plasma membrane GO:0072659 93 0.266
guanosine containing compound metabolic process GO:1901068 244 0.266
tissue morphogenesis GO:0048729 96 0.266
Human Worm Fly
anatomical structure homeostasis GO:0060249 100 0.266
maintenance of cell polarity GO:0030011 2 0.265
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.264
Worm
heart development GO:0007507 95 0.263
Zebrafish Fly
melanin biosynthetic process GO:0042438 1 0.261
hindlimb morphogenesis GO:0035137 2 0.260
positive regulation of sulfur metabolic process GO:0051176 3 0.256
Human
heart formation GO:0060914 2 0.254
Fly
regulation of actin cytoskeleton organization GO:0032956 116 0.253
regulation of cell matrix adhesion GO:0001952 42 0.252
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.252
regulation of neural precursor cell proliferation GO:2000177 4 0.249
regulation of canonical wnt signaling pathway GO:0060828 88 0.248
purine ribonucleotide catabolic process GO:0009154 404 0.247
protein localization to nucleus GO:0034504 136 0.246
ossification GO:0001503 121 0.246
positive regulation of melanosome transport GO:1902910 1 0.240
positive regulation of epithelial cell proliferation GO:0050679 65 0.240
amine metabolic process GO:0009308 44 0.239
protein import GO:0017038 130 0.236
homotypic cell cell adhesion GO:0034109 47 0.236
regulation of wnt signaling pathway GO:0030111 123 0.235
Zebrafish
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.232
digestive system development GO:0055123 75 0.230
Worm Fly
osteoblast differentiation GO:0001649 92 0.230
regulation of myeloid leukocyte differentiation GO:0002761 39 0.229
cardiac cell fate specification GO:0060912 1 0.229
Fly
gastrulation GO:0007369 51 0.227
Worm Fly
positive regulation of protein transport GO:0051222 135 0.227
regulation of behavior GO:0050795 82 0.224
regulation of cell cycle process GO:0010564 266 0.223
Human
establishment of planar polarity GO:0001736 3 0.220
protein targeting GO:0006605 187 0.220
positive regulation of programmed cell death GO:0043068 249 0.219
Human
positive regulation of cell cycle GO:0045787 140 0.219
regulation of nucleocytoplasmic transport GO:0046822 98 0.218
endothelial cell migration GO:0043542 86 0.217
positive regulation of cell migration GO:0030335 172 0.215
negative regulation of hair follicle development GO:0051799 1 0.212
positive regulation of melanin biosynthetic process GO:0048023 1 0.209
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.208
purine containing compound catabolic process GO:0072523 411 0.208
cell projection assembly GO:0030031 126 0.208
regulation of cellular ketone metabolic process GO:0010565 50 0.206
female gamete generation GO:0007292 2 0.206
Fly
ventricular cardiac muscle tissue morphogenesis GO:0055010 14 0.205
regulation of myelination GO:0031641 1 0.203
positive regulation of cell differentiation GO:0045597 211 0.201
Human
hair follicle maturation GO:0048820 3 0.201
morphogenesis of a polarized epithelium GO:0001738 3 0.199
cellular response to indole 3 methanol GO:0071681 5 0.198
positive regulation of secondary metabolite biosynthetic process GO:1900378 1 0.197
regulation of monocyte differentiation GO:0045655 5 0.196
regulation of cardioblast differentiation GO:0051890 4 0.194
Fly
cell morphogenesis GO:0000902 296 0.194
Human Fly
establishment of protein localization to plasma membrane GO:0090002 68 0.194
regulation of cytoskeleton organization GO:0051493 177 0.193
Human
cardiac ventricle morphogenesis GO:0003208 20 0.193
purine nucleoside triphosphate catabolic process GO:0009146 392 0.192
central nervous system development GO:0007417 123 0.188
intracellular protein transport GO:0006886 270 0.188
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.187
muscle structure development GO:0061061 98 0.186
gland morphogenesis GO:0022612 8 0.184
negative regulation of cell differentiation GO:0045596 171 0.180
Fly
positive regulation of hydrolase activity GO:0051345 331 0.180
regulation of catagen GO:0051794 3 0.180
transforming growth factor beta production GO:0071604 14 0.179
neuron differentiation GO:0030182 138 0.178
Fly
regulation of stem cell proliferation GO:0072091 15 0.178
cell junction maintenance GO:0034331 4 0.176
embryonic epithelial tube formation GO:0001838 4 0.175
response to nitrogen compound GO:1901698 184 0.175
muscle tissue morphogenesis GO:0060415 19 0.174
lamellipodium assembly GO:0030032 26 0.171
cytoplasmic transport GO:0016482 379 0.169
regulation of muscle system process GO:0090257 53 0.169
positive regulation of immune system process GO:0002684 283 0.169
nitrogen compound transport GO:0071705 191 0.166
negative regulation of locomotion GO:0040013 118 0.165
embryonic forelimb morphogenesis GO:0035115 4 0.164
cellular response to organonitrogen compound GO:0071417 124 0.163
regulation of establishment of protein localization GO:0070201 242 0.162
neurotransmitter secretion GO:0007269 4 0.162
negative regulation of multicellular organismal process GO:0051241 317 0.161
Zebrafish Fly
mesodermal cell fate commitment GO:0001710 2 0.160
regulation of epithelial cell proliferation GO:0050678 113 0.158
ectoderm development GO:0007398 3 0.157
protein localization to cell surface GO:0034394 28 0.156
Human
pigment metabolic process GO:0042440 16 0.155
regulation of cell substrate adhesion GO:0010810 68 0.154
cellular response to organic cyclic compound GO:0071407 127 0.154
purine nucleoside triphosphate metabolic process GO:0009144 412 0.154
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.153
locomotory behavior GO:0007626 1 0.152
regulation of cellular amine metabolic process GO:0033238 11 0.151
morphogenesis of an epithelium GO:0002009 60 0.151
Human Worm Fly
regulation of hair follicle maturation GO:0048819 3 0.150
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.150
regulation of small gtpase mediated signal transduction GO:0051056 156 0.147
muscle tissue development GO:0060537 62 0.147
regulation of cell development GO:0060284 161 0.147
Human
response to wounding GO:0009611 168 0.146
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.146
neural tube formation GO:0001841 3 0.146
actin cytoskeleton organization GO:0030036 207 0.144
brain development GO:0007420 97 0.144
regulation of nucleoside metabolic process GO:0009118 209 0.144
nucleoside phosphate catabolic process GO:1901292 412 0.143
glycoprotein biosynthetic process GO:0009101 91 0.143
Human
regulation of cell cycle GO:0051726 393 0.142
Human
internal peptidyl lysine acetylation GO:0018393 97 0.142
cytokine production GO:0001816 247 0.141
positive regulation of transport GO:0051050 336 0.141
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 1 0.140
Fly
cellular macromolecule catabolic process GO:0044265 380 0.139
multicellular organismal homeostasis GO:0048871 67 0.136
regulation of heart induction GO:0090381 2 0.136
Fly
regulation of mesenchymal cell proliferation GO:0010464 5 0.135
intermediate filament cytoskeleton organization GO:0045104 17 0.135
regulation of binding GO:0051098 111 0.135
nephron tubule epithelial cell differentiation GO:0072160 3 0.134
regulation of cytokine production GO:0001817 232 0.134
regulation of hair follicle development GO:0051797 5 0.134
negative regulation of cell fate specification GO:0009996 3 0.134
Fly
regulation of protein transport GO:0051223 213 0.131
hair cell differentiation GO:0035315 2 0.131
glial cell migration GO:0008347 4 0.130
stem cell proliferation GO:0072089 25 0.128
lamellipodium organization GO:0097581 30 0.128
cell morphogenesis involved in differentiation GO:0000904 144 0.127
Human
purine nucleotide catabolic process GO:0006195 405 0.124
gtp catabolic process GO:0006184 237 0.121
cell cell adhesion involved in gastrulation GO:0070586 6 0.121
mitotic cell cycle process GO:1903047 286 0.121
Worm
epidermal cell differentiation GO:0009913 45 0.119
leukocyte differentiation GO:0002521 98 0.119
peripheral nervous system development GO:0007422 2 0.118
muscle cell proliferation GO:0033002 35 0.118
Human
negative regulation of cell cell adhesion GO:0022408 27 0.117
Fly
epidermis morphogenesis GO:0048730 3 0.116
positive regulation of response to external stimulus GO:0032103 88 0.116
signal release GO:0023061 70 0.116
regulation of chromosome segregation GO:0051983 44 0.115
Human
coagulation GO:0050817 78 0.114
response to alcohol GO:0097305 64 0.113
protein localization to cell junction GO:1902414 3 0.112
Fly
adherens junction assembly GO:0034333 34 0.112
Human Fly
second messenger mediated signaling GO:0019932 78 0.112
regulation of microtubule cytoskeleton organization GO:0070507 61 0.112
Human
hair cycle process GO:0022405 12 0.111
positive regulation of gtpase activity GO:0043547 166 0.111
vascular process in circulatory system GO:0003018 29 0.111
rac protein signal transduction GO:0016601 12 0.109
negative regulation of cell motility GO:2000146 104 0.109
positive regulation of monophenol monooxygenase activity GO:0032773 1 0.109
positive regulation of chemotaxis GO:0050921 57 0.109
regulation of epidermis development GO:0045682 19 0.109
negative regulation of transforming growth factor beta production GO:0071635 4 0.108
regulation of determination of dorsal identity GO:2000015 2 0.108
regulation of cell morphogenesis GO:0022604 153 0.107
Human Fly
cell division GO:0051301 168 0.106
nervous system development GO:0007399 293 0.102
Fly
regulation of intracellular transport GO:0032386 195 0.102
regulation of nervous system development GO:0051960 88 0.102
hair cycle GO:0042633 28 0.102
positive regulation of leukocyte differentiation GO:1902107 37 0.100
positive regulation of cellular component movement GO:0051272 181 0.099
internal protein amino acid acetylation GO:0006475 101 0.098
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.098
Human
cardiac chamber morphogenesis GO:0003206 26 0.097
regulation of glial cell differentiation GO:0045685 3 0.097
oocyte differentiation GO:0009994 2 0.097
cellular response to alcohol GO:0097306 29 0.096
somatic stem cell maintenance GO:0035019 4 0.096
Fly
anterior posterior axis specification GO:0009948 2 0.095
microtubule cytoskeleton organization GO:0000226 176 0.095
Human Worm
positive regulation of gtp catabolic process GO:0033126 166 0.094
protein oligomerization GO:0051259 173 0.094
Rat
head development GO:0060322 108 0.093
cellular response to peptide hormone stimulus GO:0071375 56 0.093
histone h4 acetylation GO:0043967 47 0.092
cellular amine metabolic process GO:0044106 41 0.092
positive regulation of cellular component organization GO:0051130 376 0.092
Human
regulation of chemotaxis GO:0050920 74 0.092
regulation of keratinocyte proliferation GO:0010837 11 0.091
cytokinesis GO:0000910 96 0.091
positive regulation of myeloid cell differentiation GO:0045639 39 0.091
regulation of endothelial cell differentiation GO:0045601 4 0.091
organ induction GO:0001759 4 0.090
Fly
neurogenesis GO:0022008 169 0.090
Fly
response to organic cyclic compound GO:0014070 204 0.090
regulation of leukocyte differentiation GO:1902105 61 0.089
ribonucleoside catabolic process GO:0042454 406 0.088
positive regulation of glycoprotein metabolic process GO:1903020 8 0.088
Human
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.088
embryonic hindlimb morphogenesis GO:0035116 2 0.087
hematopoietic or lymphoid organ development GO:0048534 186 0.086
muscle organ development GO:0007517 56 0.086
sulfur compound biosynthetic process GO:0044272 38 0.086
Human
male genitalia development GO:0030539 1 0.085
phenol containing compound metabolic process GO:0018958 12 0.085
positive regulation of catabolic process GO:0009896 310 0.085
nucleoside triphosphate catabolic process GO:0009143 394 0.085
hemopoiesis GO:0030097 180 0.084
regulation of vesicle mediated transport GO:0060627 130 0.084
posttranscriptional regulation of gene expression GO:0010608 213 0.084
protein maturation GO:0051604 233 0.083
regulation of transforming growth factor beta production GO:0071634 13 0.082
mitotic cell cycle GO:0000278 326 0.081
Worm
chromatin modification GO:0016568 298 0.081
specification of axis polarity GO:0065001 1 0.081
Worm
regulation of secondary metabolic process GO:0043455 2 0.081
blood vessel development GO:0001568 172 0.081
extrinsic apoptotic signaling pathway GO:0097191 119 0.081
negative regulation of cardioblast differentiation GO:0051892 2 0.081
Fly
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.080
regulation of neurogenesis GO:0050767 82 0.080
positive regulation of intracellular protein transport GO:0090316 76 0.080
regulation of response to wounding GO:1903034 101 0.080
negative regulation of apoptotic process GO:0043066 316 0.080
Human
myeloid leukocyte differentiation GO:0002573 60 0.079
cellular protein complex assembly GO:0043623 188 0.079
regulation of anatomical structure morphogenesis GO:0022603 286 0.078
Human Fly
response to lipid GO:0033993 206 0.078
Human
epithelial cell migration GO:0010631 119 0.077
positive regulation of heparan sulfate proteoglycan biosynthetic process GO:0010909 3 0.077
Human
anterior posterior axis specification embryo GO:0008595 2 0.077
nucleoside triphosphate metabolic process GO:0009141 422 0.077
cell projection morphogenesis GO:0048858 129 0.076
negative regulation of neural precursor cell proliferation GO:2000178 1 0.075
cardiac ventricle development GO:0003231 23 0.075
positive regulation of monooxygenase activity GO:0032770 14 0.074
positive regulation of cell substrate adhesion GO:0010811 37 0.073
epithelial cell proliferation GO:0050673 128 0.072
digestive tract morphogenesis GO:0048546 56 0.072
Worm Fly
positive regulation of cell proliferation GO:0008284 301 0.071
ameboidal type cell migration GO:0001667 135 0.071
leukocyte migration GO:0050900 107 0.071
regulation of gtpase activity GO:0043087 180 0.071
maintenance of location GO:0051235 112 0.071
defense response GO:0006952 315 0.071
regulation of secondary metabolite biosynthetic process GO:1900376 1 0.070
growth GO:0040007 202 0.069
Fly
nucleoside monophosphate metabolic process GO:0009123 191 0.069
cellular ketone metabolic process GO:0042180 80 0.069
nucleocytoplasmic transport GO:0006913 176 0.069
regulation of protein kinase activity GO:0045859 289 0.068
Worm
semaphorin plexin signaling pathway GO:0071526 4 0.068
cellular component morphogenesis GO:0032989 314 0.067
Human Fly
regulation of microtubule based process GO:0032886 74 0.067
Human
regulation of apoptotic signaling pathway GO:2001233 175 0.067
gastrulation with mouth forming second GO:0001702 1 0.067
catenin import into nucleus GO:0035411 18 0.067
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.066
neuronal action potential GO:0019228 9 0.066
regulation of attachment of spindle microtubules to kinetochore GO:0051988 9 0.066
positive regulation of protein phosphorylation GO:0001934 313 0.065
Worm
forebrain development GO:0030900 26 0.065
cell growth GO:0016049 160 0.065
mating GO:0007618 1 0.065
Worm
positive regulation of neural precursor cell proliferation GO:2000179 2 0.065
anatomical structure formation involved in morphogenesis GO:0048646 284 0.065
Worm Fly
oocyte development GO:0048599 1 0.064
regulation of cellular component biogenesis GO:0044087 281 0.064
response to drug GO:0042493 81 0.064
Human
positive regulation of transcription factor import into nucleus GO:0042993 25 0.064
negative regulation of cell adhesion GO:0007162 64 0.063
Fly
regulation of leukocyte migration GO:0002685 63 0.063
ribonucleoside triphosphate catabolic process GO:0009203 391 0.063
regulation of ras gtpase activity GO:0032318 128 0.062
i kappab kinase nf kappab signaling GO:0007249 166 0.062
epithelium migration GO:0090132 119 0.062
positive regulation of ras gtpase activity GO:0032320 117 0.061
regulation of protein maturation GO:1903317 150 0.061
apoptotic signaling pathway GO:0097190 268 0.061
regulation of protein localization to cell surface GO:2000008 15 0.061
Human
neuron projection development GO:0031175 106 0.061
mesenchymal cell proliferation GO:0010463 7 0.061
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 19 0.060
innate immune response GO:0045087 178 0.060
regulation of immune response GO:0050776 201 0.060
positive regulation of organelle organization GO:0010638 195 0.060
regulation of protein localization to nucleus GO:1900180 85 0.060
neuron development GO:0048666 113 0.060
inflammatory response GO:0006954 79 0.060
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.060
protein catabolic process GO:0030163 325 0.059
positive regulation of phosphorylation GO:0042327 394 0.059
Worm
positive regulation of developmental process GO:0051094 314 0.058
Human Worm Fly
positive regulation of cytokinesis GO:0032467 29 0.058
protein localization to organelle GO:0033365 280 0.058
peptide cross linking GO:0018149 12 0.058
endothelial cell proliferation GO:0001935 65 0.058
regulation of response to external stimulus GO:0032101 222 0.058
blastoderm segmentation GO:0007350 2 0.057
nucleoside monophosphate catabolic process GO:0009125 159 0.057
lysosomal transport GO:0007041 33 0.057

JUP disease predictions

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 114 0.967
musculoskeletal system disease DOID:17 223 0.967
muscle tissue disease DOID:66 113 0.903
myopathy DOID:423 104 0.758
heart disease DOID:114 68 0.758
cardiomyopathy DOID:0050700 50 0.758
intrinsic cardiomyopathy DOID:0060036 50 0.758
cardiovascular system disease DOID:1287 106 0.758
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 9 0.758
urinary system disease DOID:18 40 0.309
disease of metabolism DOID:0014667 295 0.199
reproductive organ cancer DOID:193 23 0.150
Human
female reproductive organ cancer DOID:120 10 0.150
Human
cancer DOID:162 167 0.150
Human
disease of cellular proliferation DOID:14566 174 0.150
Human
organ system cancer DOID:0050686 164 0.150
Human
kidney disease DOID:557 36 0.134
carbohydrate metabolism disease DOID:0050013 32 0.106
acquired metabolic disease DOID:0060158 58 0.106