Homo sapiens

59 known processes

KAT2A

K(lysine) acetyltransferase 2A

(Aliases: GCN5L2,hGCN5,GCN5,MGC102791,PCAF-b)

KAT2A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone deubiquitination GO:0016578 16 1.000
internal protein amino acid acetylation GO:0006475 101 1.000
internal peptidyl lysine acetylation GO:0018393 97 1.000
chromatin modification GO:0016568 298 1.000
histone h3 acetylation GO:0043966 45 1.000
chromatin organization GO:0006325 351 0.999
covalent chromatin modification GO:0016569 254 0.999
histone acetylation GO:0016573 93 0.999
protein acetylation GO:0006473 116 0.996
histone modification GO:0016570 251 0.992
protein acylation GO:0043543 138 0.990
protein deubiquitination GO:0016579 79 0.980
peptidyl lysine acetylation GO:0018394 101 0.954
peptidyl lysine modification GO:0018205 144 0.943
dna templated transcription initiation GO:0006352 35 0.910
protein modification by small protein removal GO:0070646 92 0.623
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.564
histone h4 acetylation GO:0043967 47 0.507
Mouse Fly
post embryonic development GO:0009791 2 0.334
posttranscriptional regulation of gene expression GO:0010608 213 0.327
glial cell migration GO:0008347 4 0.273
regulation of cell cycle GO:0051726 393 0.199
chromatin remodeling GO:0006338 55 0.194
Human Fly
mitotic cell cycle GO:0000278 326 0.187
histone methylation GO:0016571 60 0.169
regulation of mitotic cell cycle GO:0007346 189 0.142
regulation of histone modification GO:0031056 47 0.137
neural tube formation GO:0001841 3 0.134
Mouse
regulation of growth rate GO:0040009 1 0.130
single organism cellular localization GO:1902580 332 0.110
cellular ketone metabolic process GO:0042180 80 0.109
Mouse
cellular amino acid metabolic process GO:0006520 116 0.105
histone exchange GO:0043486 3 0.100
regulation of cellular amino acid metabolic process GO:0006521 6 0.099
cytokinesis GO:0000910 96 0.099
cellular response to endogenous stimulus GO:0071495 336 0.087
Human
regulation of protein stability GO:0031647 87 0.086
nervous system development GO:0007399 293 0.082
Mouse Fly
methylation GO:0032259 106 0.079
neurogenesis GO:0022008 169 0.076
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.076
protein methylation GO:0006479 74 0.073
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.070
amine metabolic process GO:0009308 44 0.069
regeneration GO:0031099 4 0.065
establishment of tissue polarity GO:0007164 3 0.063
histone h3 k79 methylation GO:0034729 2 0.063
maintenance of location GO:0051235 112 0.063
epithelium development GO:0060429 227 0.061
Mouse
macromolecule methylation GO:0043414 97 0.061
nucleosome organization GO:0034728 66 0.060
cellular amine metabolic process GO:0044106 41 0.059
cellular response to dna damage stimulus GO:0006974 379 0.059
protein modification by small protein conjugation GO:0032446 342 0.058
protein dna complex subunit organization GO:0071824 80 0.058
regulation of cellular ketone metabolic process GO:0010565 50 0.056
Mouse
mitotic cell cycle process GO:1903047 286 0.056
regulation of chromatin organization GO:1902275 56 0.056
epithelial cell differentiation GO:0030855 141 0.054
regulation of chromosome organization GO:0033044 103 0.053
negative regulation of cell cycle GO:0045786 193 0.052
growth GO:0040007 202 0.051
Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.050
lipid localization GO:0010876 106 0.049
negative regulation of apoptotic process GO:0043066 316 0.047
purine nucleoside triphosphate metabolic process GO:0009144 412 0.046
protein alkylation GO:0008213 74 0.046
histone h3 k4 methylation GO:0051568 27 0.046
regulation of kinase activity GO:0043549 314 0.046
protein localization to organelle GO:0033365 280 0.045
chemotaxis GO:0006935 157 0.045
response to oxygen containing compound GO:1901700 369 0.045
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.044
organelle fission GO:0048285 149 0.044
mitochondrion organization GO:0007005 156 0.043
morphogenesis of a polarized epithelium GO:0001738 3 0.043
response to hormone GO:0009725 175 0.043
Human
tissue morphogenesis GO:0048729 96 0.042
Mouse
taxis GO:0042330 157 0.041
positive regulation of programmed cell death GO:0043068 249 0.040
tube closure GO:0060606 3 0.040
Mouse
regulation of chromatin modification GO:1903308 51 0.040
regulation of cell cycle process GO:0010564 266 0.040
monocarboxylic acid biosynthetic process GO:0072330 67 0.039
positive regulation of cellular amine metabolic process GO:0033240 7 0.038
somitogenesis GO:0001756 2 0.037
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.036
anatomical structure formation involved in morphogenesis GO:0048646 284 0.034
Mouse
protein oligomerization GO:0051259 173 0.034
enteric nervous system development GO:0048484 1 0.033
response to lipid GO:0033993 206 0.033
embryo development GO:0009790 123 0.033
Mouse
immune system development GO:0002520 195 0.032
establishment of planar polarity GO:0001736 3 0.032
cell morphogenesis involved in differentiation GO:0000904 144 0.030
Fly
regulation of growth GO:0040008 165 0.029
regulation of embryonic development GO:0045995 20 0.029
endocytosis GO:0006897 159 0.029
regulation of transferase activity GO:0051338 355 0.029
determination of adult lifespan GO:0008340 2 0.029
lipid metabolic process GO:0006629 381 0.028
protein homooligomerization GO:0051260 100 0.028
cell morphogenesis GO:0000902 296 0.028
Fly
mitotic cell cycle phase transition GO:0044772 162 0.028
axis elongation GO:0003401 4 0.028
negative regulation of cell death GO:0060548 345 0.028
purine nucleoside catabolic process GO:0006152 398 0.027
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.027
cellular protein complex assembly GO:0043623 188 0.027
regulation of dna metabolic process GO:0051052 153 0.026
segmentation GO:0035282 4 0.026
Mouse
tissue regeneration GO:0042246 3 0.026
protein ubiquitination GO:0016567 314 0.025
regulation of protein kinase activity GO:0045859 289 0.025
microtubule cytoskeleton organization GO:0000226 176 0.025
positive regulation of cell death GO:0010942 263 0.025
positive regulation of kinase activity GO:0033674 204 0.024
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
positive regulation of gtpase activity GO:0043547 166 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.024
purine ribonucleoside catabolic process GO:0046130 398 0.024
metencephalon development GO:0022037 2 0.024
Mouse
thymus development GO:0048538 3 0.023
positive regulation of protein phosphorylation GO:0001934 313 0.023
dna repair GO:0006281 198 0.023
negative regulation of cell proliferation GO:0008285 228 0.023
Human
negative regulation of cell cycle process GO:0010948 121 0.022
rna processing GO:0006396 255 0.022
hindbrain development GO:0030902 3 0.021
Mouse
photoreceptor cell differentiation GO:0046530 2 0.021
cellular lipid metabolic process GO:0044255 303 0.021
modification dependent protein catabolic process GO:0019941 209 0.021
histone lysine methylation GO:0034968 50 0.021
cell development GO:0048468 328 0.021
Fly
regulation of nucleotide catabolic process GO:0030811 205 0.021
regulation of epithelial cell proliferation GO:0050678 113 0.020
peripheral nervous system development GO:0007422 2 0.020
intracellular receptor signaling pathway GO:0030522 104 0.020
neuron development GO:0048666 113 0.020
Fly
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.020
cation homeostasis GO:0055080 189 0.020
central nervous system development GO:0007417 123 0.020
Mouse
trabecula morphogenesis GO:0061383 2 0.020
negative regulation of programmed cell death GO:0043069 321 0.020
stem cell development GO:0048864 69 0.020
anterior posterior axis specification GO:0009948 2 0.020
positive regulation of apoptotic process GO:0043065 246 0.019
positive regulation of cell proliferation GO:0008284 301 0.019
establishment of protein localization to organelle GO:0072594 172 0.019
cellular divalent inorganic cation homeostasis GO:0072503 128 0.019
response to light stimulus GO:0009416 87 0.019
cell cycle phase transition GO:0044770 173 0.019
nucleocytoplasmic transport GO:0006913 176 0.019
positive regulation of cell differentiation GO:0045597 211 0.019
apoptotic signaling pathway GO:0097190 268 0.019
multicellular organismal aging GO:0010259 3 0.019
nucleotide catabolic process GO:0009166 408 0.019
receptor mediated endocytosis GO:0006898 84 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
neurotransmitter secretion GO:0007269 4 0.018
memory GO:0007613 3 0.018
chemical homeostasis GO:0048878 306 0.018
dna damage checkpoint GO:0000077 68 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
regulation of histone acetylation GO:0035065 19 0.018
response to abiotic stimulus GO:0009628 336 0.018
mrna metabolic process GO:0016071 175 0.018
response to uv GO:0009411 73 0.018
negative regulation of developmental process GO:0051093 247 0.018
protein dna complex assembly GO:0065004 64 0.018
mitotic nuclear division GO:0007067 119 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
regulation of mitotic cell cycle phase transition GO:1901990 118 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
inner ear morphogenesis GO:0042472 4 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
small molecule biosynthetic process GO:0044283 157 0.017
negative regulation of mitotic cell cycle GO:0045930 102 0.017
response to external biotic stimulus GO:0043207 261 0.017
reproductive process GO:0022414 106 0.017
generation of precursor metabolites and energy GO:0006091 68 0.017
response to other organism GO:0051707 261 0.016
ossification GO:0001503 121 0.016
mapk cascade GO:0000165 288 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
cytoplasmic transport GO:0016482 379 0.016
cellular protein catabolic process GO:0044257 261 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
oogenesis GO:0048477 2 0.016
histone deacetylation GO:0016575 32 0.016
respiratory chain complex iv assembly GO:0008535 9 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
rna splicing GO:0008380 131 0.016
protein stabilization GO:0050821 64 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.016
androgen receptor signaling pathway GO:0030521 34 0.016
mitochondrial respiratory chain complex i biogenesis GO:0097031 16 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
positive regulation of transport GO:0051050 336 0.016
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.015
histone h2a acetylation GO:0043968 12 0.015
regulation of receptor activity GO:0010469 47 0.015
regulation of peptidase activity GO:0052547 180 0.015
positive regulation of growth GO:0045927 58 0.015
negative regulation of catalytic activity GO:0043086 335 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
ovulation cycle GO:0042698 9 0.015
oocyte differentiation GO:0009994 2 0.015
blastoderm segmentation GO:0007350 2 0.015
organic acid biosynthetic process GO:0016053 97 0.015
biological adhesion GO:0022610 331 0.015
defense response GO:0006952 315 0.015
head development GO:0060322 108 0.015
Mouse
hepatocyte differentiation GO:0070365 1 0.015
female gamete generation GO:0007292 2 0.015
cellular macromolecular complex assembly GO:0034622 324 0.015
cellular homeostasis GO:0019725 196 0.014
fatty acid biosynthetic process GO:0006633 46 0.014
cell adhesion GO:0007155 325 0.014
dna replication GO:0006260 116 0.014
autonomic nervous system development GO:0048483 1 0.014
cardiovascular system development GO:0072358 262 0.014
system process GO:0003008 349 0.014
vesicle mediated transport GO:0016192 371 0.014
negative regulation of cellular protein metabolic process GO:0032269 353 0.014
regulation of binding GO:0051098 111 0.014
neural tube closure GO:0001843 3 0.014
Mouse
protein catabolic process GO:0030163 325 0.014
single organism reproductive process GO:0044702 98 0.014
regulation of cell cycle phase transition GO:1901987 126 0.014
rho protein signal transduction GO:0007266 26 0.014
monocarboxylic acid metabolic process GO:0032787 185 0.014
epithelial cell proliferation GO:0050673 128 0.014
protein import GO:0017038 130 0.014
mitotic cell cycle checkpoint GO:0007093 68 0.014
embryonic placenta development GO:0001892 1 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
er nucleus signaling pathway GO:0006984 23 0.014
neuron projection development GO:0031175 106 0.014
Fly
cell type specific apoptotic process GO:0097285 125 0.014
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.014
immune response GO:0006955 307 0.014
metal ion homeostasis GO:0055065 169 0.014
developmental programmed cell death GO:0010623 3 0.014
positive regulation of innate immune response GO:0045089 79 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
response to organonitrogen compound GO:0010243 156 0.013
Human
purine nucleotide catabolic process GO:0006195 405 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
innate immune response GO:0045087 178 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
canonical wnt signaling pathway GO:0060070 116 0.013
protein deacetylation GO:0006476 38 0.013
cellular chemical homeostasis GO:0055082 180 0.013
actin mediated cell contraction GO:0070252 12 0.013
multicellular organismal reproductive process GO:0048609 40 0.013
macromolecule deacylation GO:0098732 41 0.013
response to biotic stimulus GO:0009607 276 0.013
response to nitrogen compound GO:1901698 184 0.013
Human
purine containing compound catabolic process GO:0072523 411 0.013
calcium ion homeostasis GO:0055074 122 0.013
ion homeostasis GO:0050801 230 0.013
regulation of protein localization to nucleus GO:1900180 85 0.013
response to axon injury GO:0048678 1 0.013
glycoprotein metabolic process GO:0009100 110 0.013
Human
protein polyubiquitination GO:0000209 110 0.013
nitrogen compound transport GO:0071705 191 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
compound eye development GO:0048749 1 0.013
primary neural tube formation GO:0014020 3 0.012
Mouse
regulation of cell development GO:0060284 161 0.012
nucleotide excision repair GO:0006289 31 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.012
glial cell development GO:0021782 7 0.012
negative regulation of protein modification process GO:0031400 200 0.012
organophosphate catabolic process GO:0046434 430 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
Mouse
actin filament based movement GO:0030048 17 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
regulation of protein transport GO:0051223 213 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
cofactor metabolic process GO:0051186 87 0.012
organelle assembly GO:0070925 176 0.012
regulation of cell adhesion GO:0030155 166 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
eye photoreceptor cell differentiation GO:0001754 2 0.012
hemopoiesis GO:0030097 180 0.012
blastocyst development GO:0001824 3 0.012
oocyte development GO:0048599 1 0.012
spermatid development GO:0007286 4 0.012
mitochondrial membrane organization GO:0007006 40 0.012
regulation of protein localization GO:0032880 296 0.012
regulation of cytoplasmic transport GO:1903649 149 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
convergent extension GO:0060026 1 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
single organism membrane organization GO:0044802 268 0.011
gtp metabolic process GO:0046039 239 0.011
mammary gland morphogenesis GO:0060443 2 0.011
regulation of hormone levels GO:0010817 125 0.011
gland development GO:0048732 48 0.011
cellular cation homeostasis GO:0030003 163 0.011
locomotory behavior GO:0007626 1 0.011
gtp catabolic process GO:0006184 237 0.011
cytoskeleton dependent cytokinesis GO:0061640 22 0.011
regulation of defense response GO:0031347 154 0.011
positive regulation of ras gtpase activity GO:0032320 117 0.011
schwann cell development GO:0014044 1 0.011
lens development in camera type eye GO:0002088 2 0.011
detection of mechanical stimulus GO:0050982 4 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
leukocyte differentiation GO:0002521 98 0.010
purine nucleoside triphosphate catabolic process GO:0009146 392 0.010
positive regulation of catabolic process GO:0009896 310 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010
protein targeting to nucleus GO:0044744 104 0.010
carboxylic acid biosynthetic process GO:0046394 97 0.010
positive regulation of developmental process GO:0051094 314 0.010
gonad development GO:0008406 34 0.010
nuclear transcribed mrna catabolic process GO:0000956 48 0.010
rhythmic process GO:0048511 31 0.010
generation of neurons GO:0048699 152 0.010
Fly
regulation of gtp catabolic process GO:0033124 180 0.010
nucleoside monophosphate metabolic process GO:0009123 191 0.010
negative regulation of hydrolase activity GO:0051346 182 0.010
carbohydrate metabolic process GO:0005975 207 0.010
Human Mouse

KAT2A disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.084
neurodegenerative disease DOID:1289 102 0.084
nervous system disease DOID:863 431 0.084
disease of cellular proliferation DOID:14566 174 0.031
cancer DOID:162 167 0.029
disease of metabolism DOID:0014667 295 0.029
inherited metabolic disorder DOID:655 242 0.029
sensory system disease DOID:0050155 203 0.019
musculoskeletal system disease DOID:17 223 0.016
myopathy DOID:423 104 0.015
muscular disease DOID:0080000 114 0.015
muscle tissue disease DOID:66 113 0.015
organ system cancer DOID:0050686 164 0.013
eye and adnexa disease DOID:1492 150 0.011
eye disease DOID:5614 149 0.011
brain disease DOID:936 73 0.010