Homo sapiens

175 known processes

KDM1A

lysine (K)-specific demethylase 1A

(Aliases: AOF2,LSD1,BHC110,KIAA0601,KDM1)

KDM1A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin modification GO:0016568 298 1.000
chromatin organization GO:0006325 351 1.000
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 1.000
histone modification GO:0016570 251 1.000
covalent chromatin modification GO:0016569 254 1.000
histone methylation GO:0016571 60 0.996
Mouse
atp dependent chromatin remodeling GO:0043044 25 0.996
methylation dependent chromatin silencing GO:0006346 3 0.973
macromolecule methylation GO:0043414 97 0.966
Mouse
protein deacylation GO:0035601 39 0.900
chromatin silencing at rdna GO:0000183 5 0.890
protein methylation GO:0006479 74 0.882
Mouse
digestive tract development GO:0048565 75 0.865
methylation GO:0032259 106 0.862
Mouse
chromatin remodeling GO:0006338 55 0.842
chromatin assembly or disassembly GO:0006333 78 0.836
macromolecule deacylation GO:0098732 41 0.789
peptidyl lysine modification GO:0018205 144 0.767
digestive system development GO:0055123 75 0.715
histone deacetylation GO:0016575 32 0.709
regulation of cell cycle GO:0051726 393 0.673
ribonucleoside monophosphate metabolic process GO:0009161 187 0.661
regulation of circadian rhythm GO:0042752 11 0.627
protein alkylation GO:0008213 74 0.594
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.564
response to abiotic stimulus GO:0009628 336 0.475
regulation of gene expression epigenetic GO:0040029 73 0.468
nucleoside monophosphate metabolic process GO:0009123 191 0.457
protein catabolic process GO:0030163 325 0.442
histone arginine methylation GO:0034969 6 0.428
wnt signaling pathway GO:0016055 156 0.427
histone lysine methylation GO:0034968 50 0.424
Mouse
tissue regeneration GO:0042246 3 0.421
cellular macromolecule catabolic process GO:0044265 380 0.398
cellular protein catabolic process GO:0044257 261 0.381
positive regulation of chromosome organization GO:2001252 41 0.342
regeneration GO:0031099 4 0.332
double strand break repair GO:0006302 101 0.313
regulation of megakaryocyte differentiation GO:0045652 22 0.313
Mouse
negative regulation of circadian rhythm GO:0042754 1 0.307
protein deacetylation GO:0006476 38 0.306
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.298
cellular response to decreased oxygen levels GO:0036294 51 0.267
hair follicle development GO:0001942 11 0.235
protein ubiquitination GO:0016567 314 0.232
negative regulation of intracellular signal transduction GO:1902532 183 0.222
positive regulation of protein autoubiquitination GO:1902499 2 0.219
peptidyl lysine acetylation GO:0018394 101 0.216
positive regulation of protein ubiquitination GO:0031398 53 0.214
mesenchymal cell development GO:0014031 50 0.212
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.208
positive regulation of cellular component organization GO:0051130 376 0.207
Rat
cellular response to hypoxia GO:0071456 51 0.204
ameboidal type cell migration GO:0001667 135 0.192
defense response GO:0006952 315 0.191
regulation of establishment of protein localization GO:0070201 242 0.191
cellular response to dna damage stimulus GO:0006974 379 0.190
cytokinesis GO:0000910 96 0.185
cellular macromolecular complex assembly GO:0034622 324 0.177
post embryonic development GO:0009791 2 0.170
taxis GO:0042330 157 0.160
secretion GO:0046903 254 0.160
regulation of protein ubiquitination GO:0031396 95 0.160
modification dependent macromolecule catabolic process GO:0043632 212 0.156
ubiquitin dependent protein catabolic process GO:0006511 206 0.151
rhythmic process GO:0048511 31 0.150
protein autoubiquitination GO:0051865 37 0.149
mesenchyme development GO:0060485 59 0.145
regulation of protein transport GO:0051223 213 0.137
digestive tract morphogenesis GO:0048546 56 0.135
negative regulation of axonogenesis GO:0050771 4 0.133
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.130
wound healing GO:0042060 115 0.128
purine nucleoside monophosphate metabolic process GO:0009126 186 0.127
endomembrane system organization GO:0010256 196 0.123
central nervous system development GO:0007417 123 0.122
Mouse Rat
cell fate determination GO:0001709 3 0.122
regulation of triglyceride metabolic process GO:0090207 11 0.122
chromatin silencing GO:0006342 12 0.117
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.116
regulation of protein autoubiquitination GO:1902498 3 0.116
canonical wnt signaling pathway GO:0060070 116 0.111
regulation of keratinocyte proliferation GO:0010837 11 0.110
negative regulation of protein modification process GO:0031400 200 0.105
Mouse
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.105
modification dependent protein catabolic process GO:0019941 209 0.104
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.104
proteasomal protein catabolic process GO:0010498 176 0.102
atp catabolic process GO:0006200 157 0.101
cellular response to oxidative stress GO:0034599 85 0.097
histone acetylation GO:0016573 93 0.097
regulation of protein localization GO:0032880 296 0.096
embryonic morphogenesis GO:0048598 85 0.096
negative regulation of multicellular organismal process GO:0051241 317 0.095
epithelial cell migration GO:0010631 119 0.093
histone h4 r3 methylation GO:0043985 3 0.091
circadian rhythm GO:0007623 21 0.091
posttranscriptional regulation of gene expression GO:0010608 213 0.090
megakaryocyte differentiation GO:0030219 25 0.087
Mouse
internal peptidyl lysine acetylation GO:0018393 97 0.086
response to decreased oxygen levels GO:0036293 96 0.082
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.082
positive regulation of organelle organization GO:0010638 195 0.081
microtubule based process GO:0007017 210 0.080
muscle organ development GO:0007517 56 0.079
dna repair GO:0006281 198 0.078
spindle organization GO:0007051 53 0.077
lipid catabolic process GO:0016042 84 0.077
chemotaxis GO:0006935 157 0.073
peptidyl lysine methylation GO:0018022 37 0.071
response to external biotic stimulus GO:0043207 261 0.071
cell division GO:0051301 168 0.070
regulation of canonical wnt signaling pathway GO:0060828 88 0.070
histone h4 deacetylation GO:0070933 8 0.070
response to nitrogen compound GO:1901698 184 0.068
Rat
protein acylation GO:0043543 138 0.068
negative regulation of gene expression epigenetic GO:0045814 19 0.066
cellular lipid catabolic process GO:0044242 65 0.063
protein localization to organelle GO:0033365 280 0.063
purine nucleoside monophosphate catabolic process GO:0009128 158 0.062
determination of adult lifespan GO:0008340 2 0.061
hair follicle morphogenesis GO:0031069 2 0.060
regulation of inflammatory response GO:0050727 46 0.060
oogenesis GO:0048477 2 0.060
circadian regulation of gene expression GO:0032922 8 0.060
regulation of cell motility GO:2000145 299 0.060
regulation of secretion by cell GO:1903530 177 0.060
cellular response to nitrogen compound GO:1901699 144 0.059
Rat
tube development GO:0035295 125 0.059
hair cycle GO:0042633 28 0.058
protein dephosphorylation GO:0006470 81 0.056
rna interference GO:0016246 4 0.056
regulation of response to external stimulus GO:0032101 222 0.056
generation of neurons GO:0048699 152 0.056
Rat
reproductive structure development GO:0048608 55 0.055
negative regulation of organelle organization GO:0010639 126 0.054
Mouse
protein modification by small protein conjugation GO:0032446 342 0.053
response to oxygen containing compound GO:1901700 369 0.052
Rat
regulation of myeloid cell differentiation GO:0045637 81 0.052
Mouse
vesicle mediated transport GO:0016192 371 0.052
negative regulation of wnt signaling pathway GO:0030178 69 0.051
regulation of cell growth GO:0001558 135 0.051
small molecule catabolic process GO:0044282 92 0.051
regulation of defense response GO:0031347 154 0.050
nuclear division GO:0000280 128 0.050
protein secretion GO:0009306 98 0.049
vitamin d receptor signaling pathway GO:0070561 4 0.049
protein acetylation GO:0006473 116 0.049
growth GO:0040007 202 0.048
microtubule cytoskeleton organization GO:0000226 176 0.048
circadian behavior GO:0048512 2 0.048
purine ribonucleoside metabolic process GO:0046128 437 0.048
centrosome organization GO:0051297 58 0.048
regulation of cell cycle process GO:0010564 266 0.047
regulation of epithelial to mesenchymal transition GO:0010717 37 0.047
negative regulation of apoptotic process GO:0043066 316 0.047
regulation of dna metabolic process GO:0051052 153 0.046
negative regulation of protein transport GO:0051224 75 0.045
regulation of protein binding GO:0043393 66 0.044
notch signaling involved in heart development GO:0061314 2 0.044
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.043
negative regulation of catalytic activity GO:0043086 335 0.043
regulation of proteolysis GO:0030162 293 0.043
regulation of cell development GO:0060284 161 0.041
Rat
photoreceptor cell differentiation GO:0046530 2 0.041
secretion by cell GO:0032940 226 0.039
reproductive process GO:0022414 106 0.039
dna conformation change GO:0071103 113 0.038
positive regulation of cell proliferation GO:0008284 301 0.038
Mouse
fatty acid catabolic process GO:0009062 29 0.038
regulation of chromatin modification GO:1903308 51 0.038
Mouse
regulation of mitosis GO:0007088 63 0.037
cell fate specification GO:0001708 8 0.037
tissue migration GO:0090130 119 0.036
cell growth GO:0016049 160 0.036
epithelial cell proliferation GO:0050673 128 0.036
mitotic cytokinesis GO:0000281 19 0.036
protein maturation GO:0051604 233 0.036
positive regulation of apoptotic process GO:0043065 246 0.035
response to organic cyclic compound GO:0014070 204 0.035
Rat
dephosphorylation GO:0016311 209 0.035
protein targeting to nucleus GO:0044744 104 0.035
cellular response to oxygen levels GO:0071453 55 0.034
single organism reproductive process GO:0044702 98 0.034
nucleosome positioning GO:0016584 3 0.034
embryonic organ development GO:0048568 36 0.033
Mouse
small gtpase mediated signal transduction GO:0007264 78 0.032
protein deubiquitination GO:0016579 79 0.032
regulation of locomotion GO:0040012 329 0.032
nucleoside monophosphate catabolic process GO:0009125 159 0.032
alcohol metabolic process GO:0006066 114 0.031
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.031
nervous system development GO:0007399 293 0.031
Mouse Rat
regulation of epithelial cell proliferation GO:0050678 113 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
Mouse
negative regulation of developmental process GO:0051093 247 0.030
peptidyl arginine methylation to asymmetrical dimethyl arginine GO:0019919 2 0.030
establishment of protein localization to plasma membrane GO:0090002 68 0.030
multicellular organism reproduction GO:0032504 42 0.029
rhythmic behavior GO:0007622 2 0.029
locomotory behavior GO:0007626 1 0.029
hair cycle process GO:0022405 12 0.029
epidermis morphogenesis GO:0048730 3 0.029
negative regulation of cell development GO:0010721 48 0.029
response to radiation GO:0009314 151 0.029
monocarboxylic acid catabolic process GO:0072329 37 0.029
positive regulation of programmed cell death GO:0043068 249 0.028
axis elongation GO:0003401 4 0.028
reactive oxygen species biosynthetic process GO:1903409 4 0.028
multicellular organismal reproductive process GO:0048609 40 0.028
cellular response to lipid GO:0071396 127 0.028
epithelial to mesenchymal transition GO:0001837 48 0.028
regulation of cellular component movement GO:0051270 334 0.027
peptidyl arginine n methylation GO:0035246 6 0.027
ribonucleoside monophosphate catabolic process GO:0009158 158 0.027
organic acid catabolic process GO:0016054 71 0.027
regulation of mitotic cell cycle GO:0007346 189 0.026
cell projection morphogenesis GO:0048858 129 0.026
ribonucleoside triphosphate metabolic process GO:0009199 412 0.026
cellular response to insulin stimulus GO:0032869 41 0.026
positive regulation of dna metabolic process GO:0051054 73 0.026
mesenchymal cell differentiation GO:0048762 52 0.026
rna processing GO:0006396 255 0.025
Rat
regulation of protein localization to nucleus GO:1900180 85 0.025
keratinocyte proliferation GO:0043616 17 0.025
endothelial cell proliferation GO:0001935 65 0.025
protein import GO:0017038 130 0.025
sprouting angiogenesis GO:0002040 29 0.025
dna dependent dna replication GO:0006261 44 0.024
molting cycle GO:0042303 28 0.024
protein localization to nucleus GO:0034504 136 0.024
negative regulation of steroid biosynthetic process GO:0010894 15 0.024
neural crest cell development GO:0014032 3 0.024
immune system development GO:0002520 195 0.024
Mouse
fatty acid metabolic process GO:0006631 115 0.024
microtubule organizing center organization GO:0031023 62 0.024
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.024
oocyte differentiation GO:0009994 2 0.023
purine nucleoside catabolic process GO:0006152 398 0.023
apoptotic signaling pathway GO:0097190 268 0.023
regulation of receptor biosynthetic process GO:0010869 15 0.023
carboxylic acid catabolic process GO:0046395 71 0.023
response to oxidative stress GO:0006979 121 0.023
heat acclimation GO:0010286 3 0.022
pancreas development GO:0031016 19 0.022
negative regulation of epithelial cell proliferation GO:0050680 48 0.022
negative regulation of vitamin d biosynthetic process GO:0010957 5 0.022
chordate embryonic development GO:0043009 34 0.021
Mouse
regulation of cell differentiation GO:0045595 393 0.021
Mouse Rat
hormone secretion GO:0046879 65 0.021
positive regulation of chromatin modification GO:1903310 30 0.021
positive regulation of cell differentiation GO:0045597 211 0.021
Mouse Rat
positive regulation of cell death GO:0010942 263 0.020
cell migration involved in gastrulation GO:0042074 1 0.020
organic hydroxy compound metabolic process GO:1901615 147 0.020
positive regulation of histone modification GO:0031058 29 0.020
regulation of response to wounding GO:1903034 101 0.020
asymmetric stem cell division GO:0098722 1 0.020
regulation of protein secretion GO:0050708 86 0.020
response to lipid GO:0033993 206 0.020
response to other organism GO:0051707 261 0.020
nucleosome organization GO:0034728 66 0.020
response to wounding GO:0009611 168 0.020
establishment or maintenance of cell polarity GO:0007163 31 0.020
developmental process involved in reproduction GO:0003006 66 0.020
muscle structure development GO:0061061 98 0.019
Mouse
positive regulation of hematopoietic progenitor cell differentiation GO:1901534 5 0.019
Mouse
regulation of synaptic plasticity GO:0048167 3 0.019
response to hypoxia GO:0001666 96 0.019
negative regulation of lipid metabolic process GO:0045833 38 0.019
regulation of endopeptidase activity GO:0052548 170 0.019
reproductive system development GO:0061458 56 0.019
regulation of growth GO:0040008 165 0.019
negative regulation of cell cell adhesion by negative regulation of transcription from rna polymerase ii promoter GO:1900387 1 0.019
negative regulation of transport GO:0051051 176 0.019
protein processing GO:0016485 226 0.019
organelle fission GO:0048285 149 0.019
mrna metabolic process GO:0016071 175 0.019
Rat
response to metal ion GO:0010038 84 0.019
negative regulation of kinase activity GO:0033673 106 0.019
negative regulation of cell growth GO:0030308 83 0.019
chromatin assembly GO:0031497 61 0.018
peptidyl arginine omega n methylation GO:0035247 4 0.018
cellular response to external stimulus GO:0071496 111 0.018
embryonic digestive tract morphogenesis GO:0048557 2 0.018
eye development GO:0001654 42 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.018
stem cell development GO:0048864 69 0.018
hippocampus development GO:0021766 1 0.018
response to alcohol GO:0097305 64 0.018
defense response to fungus GO:0050832 4 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.017
atp metabolic process GO:0046034 176 0.017
epidermis development GO:0008544 59 0.017
cell junction organization GO:0034330 79 0.017
cellular response to oxygen containing compound GO:1901701 276 0.017
Rat
negative regulation of histone methylation GO:0031061 6 0.017
Mouse
regulation of cellular amino acid metabolic process GO:0006521 6 0.017
cytoskeleton dependent cytokinesis GO:0061640 22 0.017
internal protein amino acid acetylation GO:0006475 101 0.017
female gamete generation GO:0007292 2 0.017
gonad development GO:0008406 34 0.017
sensory organ development GO:0007423 52 0.016
regulation of binding GO:0051098 111 0.016
neurogenesis GO:0022008 169 0.016
Rat
negative regulation of transferase activity GO:0051348 124 0.016
positive regulation of apoptotic signaling pathway GO:2001235 70 0.016
spindle assembly GO:0051225 29 0.016
inflammatory response GO:0006954 79 0.016
embryo development GO:0009790 123 0.016
Mouse
negative regulation of cellular component organization GO:0051129 235 0.016
Mouse
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.016
response to fungus GO:0009620 4 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
determination of dorsal ventral asymmetry GO:0048262 4 0.016
positive regulation of protein import into nucleus GO:0042307 46 0.016
limbic system development GO:0021761 3 0.015
negative regulation of growth GO:0045926 97 0.015
mitochondrion organization GO:0007005 156 0.015
response to organonitrogen compound GO:0010243 156 0.015
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
positive regulation of locomotion GO:0040017 186 0.015
gliogenesis GO:0042063 21 0.015
ribonucleotide catabolic process GO:0009261 405 0.015
regulation of intracellular protein transport GO:0033157 123 0.015
regulation of chromosome organization GO:0033044 103 0.015
Mouse
regulation of cell morphogenesis GO:0022604 153 0.015
positive regulation of secretion by cell GO:1903532 108 0.015
negative regulation of protein phosphorylation GO:0001933 140 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.015
cellular response to organonitrogen compound GO:0071417 124 0.015
Rat
endocytosis GO:0006897 159 0.014
dna replication GO:0006260 116 0.014
receptor mediated endocytosis GO:0006898 84 0.014
peptidyl lysine trimethylation GO:0018023 10 0.014
small molecule biosynthetic process GO:0044283 157 0.014
cellular response to extracellular stimulus GO:0031668 72 0.014
organelle assembly GO:0070925 176 0.014
camera type eye development GO:0043010 25 0.014
regulation of cell division GO:0051302 116 0.014
cellular lipid metabolic process GO:0044255 303 0.014
negative regulation of dna metabolic process GO:0051053 57 0.014
response to inorganic substance GO:0010035 127 0.014
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 20 0.014
regulation of secretion GO:0051046 194 0.014
negative regulation of cell morphogenesis involved in differentiation GO:0010771 24 0.014
regulation of wnt signaling pathway GO:0030111 123 0.013
cell cycle g2 m phase transition GO:0044839 43 0.013
cellular response to vitamin d GO:0071305 5 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
oxidation reduction process GO:0055114 396 0.013
cell morphogenesis GO:0000902 296 0.013
tricarboxylic acid metabolic process GO:0072350 4 0.013
intracellular protein transport GO:0006886 270 0.013
nuclear import GO:0051170 106 0.013
eyelid development in camera type eye GO:0061029 2 0.013
multi organism reproductive process GO:0044703 54 0.013
cellular heat acclimation GO:0070370 3 0.013
protein polymerization GO:0051258 71 0.013
positive regulation of cell motility GO:2000147 177 0.013
negative regulation of muscle organ development GO:0048635 12 0.013
regulation of glial cell differentiation GO:0045685 3 0.013
brain development GO:0007420 97 0.013
Mouse Rat
negative regulation of binding GO:0051100 57 0.013
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.012
cellular response to peptide GO:1901653 59 0.012
hemopoiesis GO:0030097 180 0.012
Mouse
cellular component morphogenesis GO:0032989 314 0.012
response to caffeine GO:0031000 3 0.012
ribonucleoside triphosphate catabolic process GO:0009203 391 0.012
regulation of cellular response to stress GO:0080135 244 0.012
osteoblast differentiation GO:0001649 92 0.012
positive regulation of synaptic transmission GO:0050806 4 0.012
regulation of intracellular transport GO:0032386 195 0.012
positive regulation of cell development GO:0010720 92 0.012
Rat
cell morphogenesis involved in differentiation GO:0000904 144 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
protein localization to plasma membrane GO:0072659 93 0.012
cellular response to peptide hormone stimulus GO:0071375 56 0.012
apical junction assembly GO:0043297 19 0.012
lipid oxidation GO:0034440 33 0.012
dna methylation or demethylation GO:0044728 19 0.012
neural tube patterning GO:0021532 2 0.012
development of primary sexual characteristics GO:0045137 35 0.012
regulation of sarcomere organization GO:0060297 3 0.012
positive regulation of cellular amine metabolic process GO:0033240 7 0.012
negative regulation of peptidase activity GO:0010466 91 0.012
nucleotide catabolic process GO:0009166 408 0.011
negative regulation of response to external stimulus GO:0032102 83 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
histone h3 k27 methylation GO:0070734 6 0.011
negative regulation of apoptotic signaling pathway GO:2001234 97 0.011
demethylation GO:0070988 37 0.011
response to ionizing radiation GO:0010212 65 0.011
sex differentiation GO:0007548 45 0.011
signal release GO:0023061 70 0.011
regulation of cellular amine metabolic process GO:0033238 11 0.011
purine nucleoside triphosphate metabolic process GO:0009144 412 0.011
generation of precursor metabolites and energy GO:0006091 68 0.011
regulation of protein localization to plasma membrane GO:1903076 40 0.011
convergent extension GO:0060026 1 0.011
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.011
positive regulation of response to external stimulus GO:0032103 88 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
fatty acid beta oxidation GO:0006635 22 0.011
secretory granule organization GO:0033363 2 0.011
protein dealkylation GO:0008214 17 0.011
cellular response to alcohol GO:0097306 29 0.011
single organism cellular localization GO:1902580 332 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
neuromuscular junction development GO:0007528 3 0.010
muscle tissue development GO:0060537 62 0.010
protein import into nucleus GO:0006606 104 0.010
cellular response to cytokine stimulus GO:0071345 181 0.010
single organism membrane fusion GO:0044801 37 0.010
signal transduction by p53 class mediator GO:0072331 72 0.010
response to extracellular stimulus GO:0009991 85 0.010
regulation of glial cell proliferation GO:0060251 4 0.010
notch signaling pathway GO:0007219 31 0.010
oocyte development GO:0048599 1 0.010

KDM1A disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.040
disease of cellular proliferation DOID:14566 174 0.040
organ system cancer DOID:0050686 164 0.015
retinal disease DOID:5679 118 0.012
retinal degeneration DOID:8466 89 0.012
sensory system disease DOID:0050155 203 0.012
eye and adnexa disease DOID:1492 150 0.012
nervous system disease DOID:863 431 0.012
eye disease DOID:5614 149 0.012