Homo sapiens

229 known processes

KDR

kinase insert domain receptor (a type III receptor tyrosine kinase)

(Aliases: CD309,VEGFR2,FLK1,VEGFR)

KDR biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of axon guidance GO:1902667 3 1.000
regulation of glomerulus development GO:0090192 3 1.000
angiogenesis involved in wound healing GO:0060055 4 0.999
positive regulation of peptidyl tyrosine autophosphorylation GO:1900086 1 0.999
positive regulation of map kinase activity GO:0043406 80 0.999
Human
negative regulation of phosphatidylinositol biosynthetic process GO:0010512 2 0.999
vascular wound healing GO:0061042 4 0.999
regulation of vascular wound healing GO:0061043 2 0.999
positive regulation of histone deacetylase activity GO:1901727 3 0.999
patterning of blood vessels GO:0001569 2 0.999
regulation of axon extension involved in axon guidance GO:0048841 2 0.999
positive regulation of vascular wound healing GO:0035470 1 0.998
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.998
retinal ganglion cell axon guidance GO:0031290 2 0.997
vegf activated platelet derived growth factor receptor signaling pathway GO:0038086 3 0.997
Human
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 2 0.997
regulation of mast cell chemotaxis GO:0060753 4 0.997
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 9 0.997
Human
vasculature development GO:0001944 181 0.996
positive regulation of focal adhesion assembly GO:0051894 11 0.996
positive regulation of mapk cascade GO:0043410 190 0.995
positive regulation of mast cell chemotaxis GO:0060754 4 0.995
activation of mapk activity GO:0000187 45 0.994
Human
cardiovascular system development GO:0072358 262 0.994
regulation of peptidyl tyrosine autophosphorylation GO:1900084 1 0.994
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.994
basophil chemotaxis GO:0002575 1 0.994
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway GO:0038091 3 0.993
Human
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.993
blood vessel development GO:0001568 172 0.992
blood vessel morphogenesis GO:0048514 162 0.991
regulation of map kinase activity GO:0043405 108 0.991
Human
positive regulation of glomerular mesangial cell proliferation GO:0072126 1 0.990
regulation of endothelial cell differentiation GO:0045601 4 0.990
Mouse
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 2 0.989
negative regulation of platelet activation GO:0010544 7 0.989
Human
regulation of mapk cascade GO:0043408 262 0.988
negative regulation of wound healing GO:0061045 25 0.988
Human
sprouting angiogenesis GO:0002040 29 0.987
Mouse
regulation of glomerular mesangial cell proliferation GO:0072124 3 0.986
positive regulation of endothelial cell migration GO:0010595 39 0.985
tor signaling GO:0031929 39 0.984
Fly
activation of protein kinase activity GO:0032147 90 0.982
Human
salivary gland morphogenesis GO:0007435 4 0.982
Fly
cell migration involved in kidney development GO:0035787 2 0.981
regulation of endothelial cell migration GO:0010594 67 0.979
motor neuron axon guidance GO:0008045 2 0.978
positive regulation of p38mapk cascade GO:1900745 8 0.976
circulatory system development GO:0072359 262 0.974
regulation of adherens junction organization GO:1903391 21 0.973
positive regulation of metanephric mesenchymal cell migration GO:2000591 2 0.973
negative regulation of axon guidance GO:1902668 1 0.973
angiogenesis GO:0001525 147 0.971
negative regulation of axon extension GO:0030517 2 0.971
tissue migration GO:0090130 119 0.969
cell matrix adhesion GO:0007160 85 0.968
negative regulation of coagulation GO:0050819 24 0.967
Human
focal adhesion assembly GO:0048041 30 0.964
cell migration involved in metanephros development GO:0035788 2 0.956
nerve development GO:0021675 4 0.954
regulation of phosphatidylinositol biosynthetic process GO:0010511 5 0.952
positive regulation of epithelial cell migration GO:0010634 55 0.949
regulation of blood coagulation GO:0030193 42 0.948
Human
regulation of locomotion GO:0040012 329 0.948
positive regulation of angiogenesis GO:0045766 51 0.943
regulation of smooth muscle cell migration GO:0014910 15 0.942
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.941
glomerular mesangial cell proliferation GO:0072110 3 0.939
metanephric mesenchymal cell migration GO:0035789 2 0.939
adherens junction organization GO:0034332 36 0.938
endothelial cell migration GO:0043542 86 0.937
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.937
cellular response to vascular endothelial growth factor stimulus GO:0035924 26 0.929
single organism cell adhesion GO:0098602 179 0.929
Human
regulation of retinal ganglion cell axon guidance GO:0090259 1 0.927
enzyme linked receptor protein signaling pathway GO:0007167 303 0.922
regulation of protein serine threonine kinase activity GO:0071900 179 0.920
Human
mapk cascade GO:0000165 288 0.919
positive regulation of cellular component movement GO:0051272 181 0.916
positive regulation of axon extension involved in axon guidance GO:0048842 1 0.915
positive regulation of cellular amine metabolic process GO:0033240 7 0.914
positive regulation of protein phosphorylation GO:0001934 313 0.914
regulation of cell migration GO:0030334 289 0.911
cell chemotaxis GO:0060326 112 0.907
Human
neural crest cell development GO:0014032 3 0.905
positive regulation of protein localization to early endosome GO:1902966 2 0.904
signal transduction by phosphorylation GO:0023014 297 0.903
cardiac vascular smooth muscle cell differentiation GO:0060947 2 0.901
positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway GO:0038033 4 0.901
negative regulation of hemostasis GO:1900047 22 0.898
Human
cellular amino acid metabolic process GO:0006520 116 0.897
regulation of transferase activity GO:0051338 355 0.897
Human
blood vessel maturation GO:0001955 1 0.893
regulation of cellular amino acid metabolic process GO:0006521 6 0.892
chemical homeostasis within a tissue GO:0048875 3 0.889
Mouse
vascular endothelial growth factor receptor signaling pathway GO:0048010 19 0.887
phosphatidylinositol mediated signaling GO:0048015 55 0.879
blood vessel endothelial cell migration GO:0043534 42 0.878
Mouse
regulation of vasculature development GO:1901342 97 0.871
regulation of histone deacetylase activity GO:1901725 3 0.864
positive regulation of protein kinase activity GO:0045860 190 0.861
Human
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.860
Human
vascular endothelial growth factor receptor 1 signaling pathway GO:0036323 1 0.852
Human
cerebral cortex cell migration GO:0021795 3 0.844
anatomical structure formation involved in morphogenesis GO:0048646 284 0.839
positive regulation of mesonephros development GO:0061213 2 0.838
leukocyte migration GO:0050900 107 0.837
Human
cell substrate adhesion GO:0031589 132 0.836
regulation of cell growth GO:0001558 135 0.833
response to growth factor GO:0070848 205 0.833
myeloid leukocyte migration GO:0097529 62 0.826
Human
branching morphogenesis of an epithelial tube GO:0048754 19 0.823
Mouse
cranial nerve morphogenesis GO:0021602 1 0.819
positive regulation of metanephros development GO:0072216 3 0.818
cell migration involved in sprouting angiogenesis GO:0002042 19 0.817
Mouse
positive regulation of endothelial cell proliferation GO:0001938 37 0.816
cellular amine metabolic process GO:0044106 41 0.814
regulation of mesonephros development GO:0061217 3 0.810
substrate dependent cerebral cortex tangential migration GO:0021825 2 0.808
positive regulation of phosphorylation GO:0042327 394 0.807
blood coagulation GO:0007596 76 0.807
Human
regulation of response to wounding GO:1903034 101 0.804
Human
lymphangiogenesis GO:0001946 7 0.804
Human
positive regulation of cell motility GO:2000147 177 0.804
peptidyl tyrosine phosphorylation GO:0018108 170 0.800
forebrain generation of neurons GO:0021872 3 0.795
urogenital system development GO:0001655 65 0.795
Fly
regulation of cell motility GO:2000145 299 0.791
regulation of cell junction assembly GO:1901888 29 0.785
organ morphogenesis GO:0009887 147 0.783
Fly
cell junction organization GO:0034330 79 0.772
regulation of cell proliferation involved in kidney development GO:1901722 3 0.771
cellular component morphogenesis GO:0032989 314 0.770
branching involved in salivary gland morphogenesis GO:0060445 1 0.768
venous blood vessel development GO:0060841 2 0.768
regulation of erk1 and erk2 cascade GO:0070372 99 0.767
positive regulation of kinase activity GO:0033674 204 0.763
Human
regulation of cell matrix adhesion GO:0001952 42 0.762
semaphorin plexin signaling pathway GO:0071526 4 0.755
positive regulation of cell substrate adhesion GO:0010811 37 0.749
regulation of vascular permeability GO:0043114 11 0.748
fibroblast proliferation GO:0048144 33 0.737
Human
regulation of behavior GO:0050795 82 0.732
positive regulation of cell proliferation GO:0008284 301 0.729
regulation of chemotaxis GO:0050920 74 0.727
lung alveolus development GO:0048286 4 0.723
Mouse
regulation of protein kinase activity GO:0045859 289 0.723
Human
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 2 0.714
regulation of cell differentiation GO:0045595 393 0.709
Human Mouse Fly
cell junction maintenance GO:0034331 4 0.707
Human
monocyte chemotaxis GO:0002548 20 0.700
Human
cellular response to hormone stimulus GO:0032870 125 0.693
Fly
regulation of kinase activity GO:0043549 314 0.689
Human
regulation of receptor internalization GO:0002090 15 0.687
positive regulation of cellular component organization GO:0051130 376 0.684
positive regulation of axon extension GO:0045773 4 0.680
chemotaxis GO:0006935 157 0.666
cell cell junction organization GO:0045216 69 0.666
positive regulation of glomerulus development GO:0090193 1 0.662
cell substrate adherens junction assembly GO:0007045 30 0.661
muscle cell proliferation GO:0033002 35 0.659
Human
response to wounding GO:0009611 168 0.656
Human
immune effector process GO:0002252 159 0.652
Human
vascular smooth muscle cell development GO:0097084 1 0.650
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.648
amine metabolic process GO:0009308 44 0.648
cellular ketone metabolic process GO:0042180 80 0.648
negative regulation of phosphate metabolic process GO:0045936 267 0.642
positive regulation of tyrosine phosphorylation of stat5 protein GO:0042523 11 0.634
Human
cyclic nucleotide metabolic process GO:0009187 82 0.633
vasculogenesis GO:0001570 8 0.630
Mouse
regulation of leukocyte chemotaxis GO:0002688 46 0.629
forebrain neuron differentiation GO:0021879 3 0.629
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.625
negative regulation of response to wounding GO:1903035 47 0.610
Human
peptidyl tyrosine modification GO:0018212 170 0.609
glomerulus development GO:0032835 15 0.606
negative regulation of cell proliferation GO:0008285 228 0.598
leukocyte chemotaxis GO:0030595 76 0.580
Human
single organismal cell cell adhesion GO:0016337 148 0.576
Human
cellular response to macrophage colony stimulating factor stimulus GO:0036006 4 0.576
Human
neuron differentiation GO:0030182 138 0.567
positive regulation of leukocyte chemotaxis GO:0002690 38 0.561
regulation of cellular component biogenesis GO:0044087 281 0.560
negative regulation of cell migration GO:0030336 102 0.558
positive regulation of transport GO:0051050 336 0.555
Human
regulation of cgmp metabolic process GO:0030823 9 0.553
biological adhesion GO:0022610 331 0.546
ectodermal placode formation GO:0060788 1 0.546
negative regulation of multicellular organismal process GO:0051241 317 0.544
Human
lung vasculature development GO:0060426 2 0.543
regulation of tyrosine phosphorylation of stat5 protein GO:0042522 12 0.542
Human
smooth muscle cell migration GO:0014909 18 0.538
Human
calcium ion import GO:0070509 23 0.536
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.530
negative chemotaxis GO:0050919 11 0.530
vascular endothelial growth factor signaling pathway GO:0038084 15 0.529
morphogenesis of a branching structure GO:0001763 21 0.527
Mouse
hemopoiesis GO:0030097 180 0.521
Human Mouse Fly
neural crest cell migration GO:0001755 2 0.519
regulation of epithelial cell migration GO:0010632 93 0.519
surfactant homeostasis GO:0043129 3 0.519
Mouse
negative regulation of axonogenesis GO:0050771 4 0.516
positive regulation of dna metabolic process GO:0051054 73 0.516
Human
melanin metabolic process GO:0006582 1 0.516
cell adhesion GO:0007155 325 0.510
nervous system development GO:0007399 293 0.504
Fly
mast cell chemotaxis GO:0002551 5 0.500
Human
negative regulation of endothelial cell apoptotic process GO:2000352 16 0.499
cell type specific apoptotic process GO:0097285 125 0.499
regulation of protein kinase c signaling GO:0090036 8 0.499
Human
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.497
Mouse
cell substrate junction assembly GO:0007044 35 0.495
kidney vasculature development GO:0061440 7 0.494
photoreceptor cell differentiation GO:0046530 2 0.492
regulation of stem cell differentiation GO:2000736 56 0.492
Human
endothelial cell chemotaxis GO:0035767 13 0.488
cell projection organization GO:0030030 252 0.487
Fly
positive regulation of locomotion GO:0040017 186 0.480
post embryonic organ development GO:0048569 1 0.478
Fly
platelet aggregation GO:0070527 32 0.477
Human
cell junction assembly GO:0034329 67 0.473
regulation of response to external stimulus GO:0032101 222 0.472
regulation of lipid kinase activity GO:0043550 19 0.470
Human
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.469
Human
blood circulation GO:0008015 113 0.468
metanephros development GO:0001656 16 0.468
coronary vasculature development GO:0060976 2 0.466
circulatory system process GO:0003013 113 0.465
regulation of cell substrate adhesion GO:0010810 68 0.455
positive regulation of protein kinase b signaling GO:0051897 42 0.455
positive regulation of chemotaxis GO:0050921 57 0.445
positive regulation of fibroblast proliferation GO:0048146 21 0.444
Human
epithelium migration GO:0090132 119 0.442
mesonephric epithelium development GO:0072163 14 0.442
regulation of protein localization GO:0032880 296 0.441
Human
negative regulation of cell death GO:0060548 345 0.440
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.439
platelet derived growth factor receptor alpha signaling pathway GO:0035790 1 0.434
Human
neuroblast proliferation GO:0007405 4 0.428
secretion GO:0046903 254 0.422
Human
regulation of coagulation GO:0050818 44 0.418
Human
lymph vessel morphogenesis GO:0036303 7 0.418
Human
positive regulation of transferase activity GO:0051347 227 0.416
Human
regulation of cellular component movement GO:0051270 334 0.416
vascular process in circulatory system GO:0003018 29 0.414
negative regulation of response to external stimulus GO:0032102 83 0.405
Human
granulocyte migration GO:0097530 40 0.399
regulation of protein localization to early endosome GO:1902965 2 0.399
cardiac muscle fiber development GO:0048739 4 0.397
regulation of positive chemotaxis GO:0050926 14 0.390
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.388
Human
cell growth GO:0016049 160 0.384
mesonephros development GO:0001823 17 0.381
response to nitrogen compound GO:1901698 184 0.380
Fly
myeloid leukocyte activation GO:0002274 34 0.378
Human
positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 0.376
Human
negative regulation of bone remodeling GO:0046851 4 0.373
chemokine production GO:0032602 32 0.373
Human
regulation of hematopoietic progenitor cell differentiation GO:1901532 24 0.370
Mouse
hemostasis GO:0007599 76 0.369
Human
erk1 and erk2 cascade GO:0070371 104 0.369
negative regulation of blood coagulation GO:0030195 22 0.366
Human
regulation of dna replication GO:0006275 68 0.364
Human
kit signaling pathway GO:0038109 1 0.363
Human
immune response GO:0006955 307 0.362
Human Fly
positive regulation of adherens junction organization GO:1903393 12 0.358
positive regulation of phospholipase activity GO:0010518 22 0.355
Human
secondary metabolic process GO:0019748 17 0.355
regulation of lipase activity GO:0060191 37 0.352
Human
response to biotic stimulus GO:0009607 276 0.348
Fly
single organism cellular localization GO:1902580 332 0.348
Human
behavior GO:0007610 112 0.348
epithelial cell proliferation GO:0050673 128 0.348
positive regulation of neural precursor cell proliferation GO:2000179 2 0.339
defense response GO:0006952 315 0.330
Fly
regulation of cell adhesion GO:0030155 166 0.329
positive regulation of jnk cascade GO:0046330 52 0.329
Human
central nervous system development GO:0007417 123 0.328
Fly
positive regulation of protein transport GO:0051222 135 0.327
Human
developmental maturation GO:0021700 28 0.325
Mouse
regulation of focal adhesion assembly GO:0051893 20 0.322
ameboidal type cell migration GO:0001667 135 0.321
mast cell migration GO:0097531 5 0.321
Human
positive regulation of hyaluronan biosynthetic process GO:1900127 3 0.321
glomerulus vasculature development GO:0072012 6 0.319
endothelial cell differentiation GO:0045446 26 0.317
Mouse
regulation of cell migration involved in sprouting angiogenesis GO:0090049 9 0.316
regulation of cellular ketone metabolic process GO:0010565 50 0.314
positive regulation of positive chemotaxis GO:0050927 13 0.314
protein autophosphorylation GO:0046777 123 0.312
calcium mediated signaling using intracellular calcium source GO:0035584 7 0.309
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.308
positive regulation of dna replication GO:0045740 35 0.306
Human
mast cell activation involved in immune response GO:0002279 4 0.306
Human
regulation of kidney development GO:0090183 10 0.305
cgmp metabolic process GO:0046068 19 0.305
response to hypoxia GO:0001666 96 0.304
cellular response to nitrogen compound GO:1901699 144 0.304
Fly
nephron development GO:0072006 30 0.303
carbohydrate derivative biosynthetic process GO:1901137 207 0.301
cell morphogenesis involved in differentiation GO:0000904 144 0.300
regulation of neuron projection development GO:0010975 57 0.300
positive regulation of cell growth GO:0030307 48 0.298
positive regulation of behavior GO:0048520 60 0.295
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.290
Human
eye photoreceptor cell differentiation GO:0001754 2 0.289
positive regulation of neuroblast proliferation GO:0002052 2 0.287
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.285
nephron morphogenesis GO:0072028 15 0.285
positive regulation of cell differentiation GO:0045597 211 0.283
Mouse
regulation of nucleotide metabolic process GO:0006140 269 0.280
ion homeostasis GO:0050801 230 0.278
Human Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.277
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.277
Human
regulation of protein tyrosine kinase activity GO:0061097 36 0.276
Human
regulation of establishment of protein localization GO:0070201 242 0.276
Human
positive regulation of leukocyte migration GO:0002687 46 0.275
cellular response to stem cell factor stimulus GO:0036216 1 0.274
Human
anatomical structure homeostasis GO:0060249 100 0.273
Mouse
regulation of angiogenesis GO:0045765 92 0.273
regulation of stress activated mapk cascade GO:0032872 84 0.272
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.271
smooth muscle cell proliferation GO:0048659 28 0.269
Human
cellular response to oxygen containing compound GO:1901701 276 0.269
Fly
vesicle mediated transport GO:0016192 371 0.267
Human
lymph vessel development GO:0001945 9 0.266
Human Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.266
Human
dna replication GO:0006260 116 0.262
Human
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.259
regulation of cell substrate junction assembly GO:0090109 20 0.257
endothelium development GO:0003158 33 0.254
Mouse
endothelial cell proliferation GO:0001935 65 0.253
receptor internalization GO:0031623 43 0.252
limbic system development GO:0021761 3 0.250
blood vessel remodeling GO:0001974 2 0.249
telencephalon cell migration GO:0022029 4 0.247
stem cell differentiation GO:0048863 93 0.247
Human
hypothalamus development GO:0021854 1 0.246
tissue remodeling GO:0048771 16 0.243
positive regulation of axon guidance GO:1902669 1 0.242
regulation of neuron differentiation GO:0045664 70 0.242
platelet activation GO:0030168 44 0.242
Human
system process GO:0003008 349 0.242
positive regulation of wound healing GO:0090303 20 0.241
tube morphogenesis GO:0035239 95 0.241
Mouse Fly
positive regulation of smooth muscle cell migration GO:0014911 6 0.236
Human
negative regulation of apoptotic process GO:0043066 316 0.235
response to peptide GO:1901652 65 0.235
Fly
phospholipid metabolic process GO:0006644 99 0.234
Human
organophosphate catabolic process GO:0046434 430 0.232
response to organonitrogen compound GO:0010243 156 0.230
Fly
kidney development GO:0001822 53 0.229
regulation of purine nucleotide metabolic process GO:1900542 264 0.227
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 7 0.226
venous blood vessel morphogenesis GO:0048845 1 0.226
positive regulation of hydrolase activity GO:0051345 331 0.224
Human
positive regulation of ion transport GO:0043270 87 0.224
positive chemotaxis GO:0050918 33 0.224
cell development GO:0048468 328 0.223
Mouse Fly
development of primary male sexual characteristics GO:0046546 23 0.222
Human
regulation of chemokine production GO:0032642 31 0.222
Human
cytokine secretion GO:0050663 64 0.221
Human
positive regulation of cell migration GO:0030335 172 0.221
heart development GO:0007507 95 0.219
Mouse
innate immune response GO:0045087 178 0.217
Fly
inositol lipid mediated signaling GO:0048017 55 0.216
positive regulation of vasoconstriction GO:0045907 3 0.215
tyrosine phosphorylation of stat protein GO:0007260 33 0.215
Human
actin cytoskeleton organization GO:0030036 207 0.215
Human Fly
response to stem cell factor GO:0036215 1 0.211
Human
stress activated protein kinase signaling cascade GO:0031098 94 0.211
Human
negative regulation of catalytic activity GO:0043086 335 0.210
positive regulation of cell development GO:0010720 92 0.209
response to progesterone GO:0032570 5 0.208
positive regulation of neuron differentiation GO:0045666 40 0.205
regulation of blood vessel endothelial cell migration GO:0043535 30 0.205
positive regulation of nervous system development GO:0051962 54 0.204
post embryonic development GO:0009791 2 0.203
Fly
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.202
response to estrogen GO:0043627 47 0.199
actin filament based process GO:0030029 224 0.199
Human Fly
regulation of wound healing GO:0061041 56 0.197
Human
positive regulation of phosphoprotein phosphatase activity GO:0032516 9 0.195
Human
spindle elongation GO:0051231 4 0.194
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.194
coagulation GO:0050817 78 0.194
Human
regulation of cell cell adhesion GO:0022407 57 0.192
lactation GO:0007595 3 0.190
regulation of cellular response to stress GO:0080135 244 0.190
Human
extrinsic apoptotic signaling pathway GO:0097191 119 0.189
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 15 0.189
cytosolic calcium ion homeostasis GO:0051480 89 0.187
Human
apoptotic signaling pathway GO:0097190 268 0.186
positive regulation of calcium ion transport GO:0051928 51 0.186
activation of protein kinase b activity GO:0032148 14 0.184
positive regulation of neurogenesis GO:0050769 49 0.184
neuron projection development GO:0031175 106 0.183
taxis GO:0042330 157 0.182
regulation of leukocyte migration GO:0002685 63 0.180
regulation of mesenchymal stem cell differentiation GO:2000739 6 0.179
Human
kidney epithelium development GO:0072073 25 0.179
positive regulation of lipid metabolic process GO:0045834 50 0.178
Human
cellular response to endogenous stimulus GO:0071495 336 0.177
Human Fly
glycosyl compound catabolic process GO:1901658 413 0.176
tyrosine phosphorylation of stat5 protein GO:0042506 13 0.175
Human
neuron development GO:0048666 113 0.174
positive regulation of cell migration by vascular endothelial growth factor signaling pathway GO:0038089 5 0.173
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.172
Human
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 3 0.169
regulation of tissue remodeling GO:0034103 9 0.166
cellular response to hepatocyte growth factor stimulus GO:0035729 6 0.166
cellular response to glucocorticoid stimulus GO:0071385 4 0.166
positive regulation of immune system process GO:0002684 283 0.165
cytokine production involved in immune response GO:0002367 27 0.164
Human
peptidyl tyrosine autophosphorylation GO:0038083 5 0.164
Mouse
renal system development GO:0072001 63 0.164
Fly
positive regulation of developmental process GO:0051094 314 0.163
cellular response to hypoxia GO:0071456 51 0.163
vascular smooth muscle cell differentiation GO:0035886 3 0.162
cerebral cortex tangential migration GO:0021800 2 0.161
smooth muscle cell differentiation GO:0051145 8 0.161
regulation of system process GO:0044057 101 0.160
epithelium development GO:0060429 227 0.157
Mouse Fly
cellular metal ion homeostasis GO:0006875 146 0.157
Human
positive regulation of secretion by cell GO:1903532 108 0.157
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.156
Human Mouse Fly
nephron tubule development GO:0072080 17 0.155
regulation of epithelial cell proliferation GO:0050678 113 0.155
calcium ion transport GO:0006816 147 0.154
positive regulation of response to external stimulus GO:0032103 88 0.154
kidney vasculature morphogenesis GO:0061439 1 0.153
regulation of neural precursor cell proliferation GO:2000177 4 0.153
negative regulation of endopeptidase activity GO:0010951 84 0.150
positive regulation of vascular permeability GO:0043117 4 0.150
single organism reproductive process GO:0044702 98 0.149
Human Mouse Fly
regulation of smooth muscle cell proliferation GO:0048660 28 0.148
Human
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.147
Human
negative regulation of bone resorption GO:0045779 2 0.146
exocytosis GO:0006887 71 0.144
Human
cellular response to growth factor stimulus GO:0071363 197 0.144
regulation of cell morphogenesis GO:0022604 153 0.143
toxin transport GO:1901998 4 0.141
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.140
negative regulation of cell development GO:0010721 48 0.139
positive regulation of secretion GO:0051047 116 0.139
Human
anatomical structure maturation GO:0071695 9 0.139
positive regulation of neuron projection development GO:0010976 34 0.138
branching involved in ureteric bud morphogenesis GO:0001658 9 0.137
cell projection morphogenesis GO:0048858 129 0.136
axon extension involved in axon guidance GO:0048846 5 0.136
organic hydroxy compound metabolic process GO:1901615 147 0.133
positive regulation of epithelial cell proliferation GO:0050679 65 0.132
cell morphogenesis GO:0000902 296 0.130
muscle cell migration GO:0014812 19 0.129
Human
regulation of growth GO:0040008 165 0.128
renal tubule development GO:0061326 19 0.127
Fly
protein localization to endosome GO:0036010 8 0.127
gland development GO:0048732 48 0.125
Fly
regulation of nervous system development GO:0051960 88 0.123
positive regulation of endothelial cell chemotaxis GO:2001028 5 0.122
response to abiotic stimulus GO:0009628 336 0.122
negative regulation of phosphorus metabolic process GO:0010563 267 0.121
artery morphogenesis GO:0048844 7 0.120
oogenesis GO:0048477 2 0.120
Fly
leukocyte activation GO:0045321 164 0.119
Human
regulation of receptor mediated endocytosis GO:0048259 32 0.118
cellular response to alcohol GO:0097306 29 0.117
growth GO:0040007 202 0.115
regeneration GO:0031099 4 0.115
negative regulation of cellular protein metabolic process GO:0032269 353 0.114
cell activation GO:0001775 213 0.114
Human
cranial nerve development GO:0021545 4 0.114
regulation of cell activation GO:0050865 125 0.114
Human
response to cytokine GO:0034097 232 0.113
Human
response to oxygen containing compound GO:1901700 369 0.113
Fly
epithelial cell migration GO:0010631 119 0.113
response to decreased oxygen levels GO:0036293 96 0.112
regulation of cellular response to growth factor stimulus GO:0090287 76 0.111
Human
male gonad development GO:0008584 23 0.111
Human
cellular ion homeostasis GO:0006873 168 0.111
Human
regulation of peptidyl serine phosphorylation GO:0033135 50 0.111
regulation of endothelial cell apoptotic process GO:2000351 24 0.110
negative regulation of cellular component movement GO:0051271 106 0.109
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.109
tissue morphogenesis GO:0048729 96 0.108
Mouse Fly
negative regulation of gliogenesis GO:0014014 3 0.108
regulation of tyrosine phosphorylation of stat1 protein GO:0042510 11 0.108
Human
nephron epithelium morphogenesis GO:0072088 15 0.108
skeletal system development GO:0001501 79 0.107
cellular response to lipid GO:0071396 127 0.106
cellular lipid metabolic process GO:0044255 303 0.106
Human
forebrain development GO:0030900 26 0.105
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 16 0.102
Human
ectodermal placode development GO:0071696 1 0.102
regulation of reactive oxygen species metabolic process GO:2000377 41 0.101
cell proliferation involved in kidney development GO:0072111 3 0.100
regulation of anatomical structure size GO:0090066 101 0.100
negative regulation of multi organism process GO:0043901 92 0.100
mast cell cytokine production GO:0032762 1 0.100
Human

KDR disease predictions

Disease DO term ID Size Probability Func Analog Org