|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.944
|
Worm Fly |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.933
|
Mouse Rat Worm Fly |
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.922
|
Mouse Rat Worm Fly |
|
|
microtubule based movement
|
GO:0007018 |
32 |
0.909
|
Mouse Rat Fly |
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.851
|
Fly |
|
|
membrane organization
|
GO:0061024 |
292 |
0.820
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.713
|
Fly |
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.699
|
Mouse Worm |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.693
|
Fly |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.688
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.682
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.667
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.658
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.655
|
Fly |
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.633
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.614
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.611
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.594
|
Fly |
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.577
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.577
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.551
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.547
|
Fly |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.544
|
Worm |
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.537
|
Fly |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.524
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.493
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.491
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.479
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.479
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.471
|
Worm Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.463
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.451
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.445
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.443
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.438
|
Worm |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.434
|
Worm |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.431
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.419
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.414
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.404
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.403
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.392
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.391
|
Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.379
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.376
|
Fly |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.376
|
Mouse Worm |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.370
|
Worm Fly |
|
|
glutamate metabolic process
|
GO:0006536 |
10 |
0.359
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.358
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.346
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.346
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.345
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.343
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.331
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.331
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.328
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.324
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.316
|
Worm |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.314
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.312
|
Mouse Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.308
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.307
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.305
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.301
|
Mouse Rat Worm Fly |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.294
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.283
|
Worm Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.282
|
Worm |
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.282
|
Fly |
|
|
oogenesis
|
GO:0048477 |
2 |
0.281
|
Fly |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.272
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.272
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.270
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.263
|
Worm |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.261
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.259
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.259
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.257
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.257
|
|
|
|
microtubule polymerization
|
GO:0046785 |
18 |
0.251
|
Fly |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.250
|
|
|
|
regulation of glutamine family amino acid metabolic process
|
GO:0000820 |
2 |
0.249
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.249
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.247
|
Fly |
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.247
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.247
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.247
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.243
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.239
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.238
|
Worm Fly |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.234
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.232
|
Worm Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.232
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.230
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.229
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.228
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.227
|
Worm |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.227
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.224
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.223
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.223
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.222
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.221
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.220
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.219
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.219
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.216
|
Fly |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.216
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.215
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.209
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.207
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.201
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.200
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.199
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.198
|
|
|
|
regulation of glucokinase activity
|
GO:0033131 |
2 |
0.197
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.196
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.196
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.196
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.194
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.194
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.194
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.191
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.190
|
|
|
|
protein depolymerization
|
GO:0051261 |
30 |
0.189
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.178
|
Fly |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.178
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.177
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
5 |
0.177
|
Worm |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.177
|
Worm |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.176
|
Worm Fly |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.173
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.171
|
Worm |
|
|
nuclear import
|
GO:0051170 |
106 |
0.170
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.169
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
5 |
0.167
|
Worm |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.165
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.165
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.163
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.163
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.163
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.160
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.158
|
Mouse Rat Worm |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.157
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.155
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.154
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.153
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.153
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.152
|
Worm Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.152
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.151
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.151
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.150
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
21 |
0.149
|
Mouse Rat Fly |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.148
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.145
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.144
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.144
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.143
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.141
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.141
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.141
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.141
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.140
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.139
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.138
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.136
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.134
|
Worm Fly |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.134
|
|
|
|
negative regulation of cellular carbohydrate metabolic process
|
GO:0010677 |
14 |
0.134
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.133
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.133
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.131
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.131
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.131
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.128
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.127
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.127
|
Worm |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.126
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.126
|
|
|
|
head development
|
GO:0060322 |
108 |
0.122
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.122
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.121
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.120
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.119
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.119
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.118
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.117
|
Worm Fly |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.116
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.116
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.115
|
Worm Fly |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.112
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.112
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.110
|
|
|
|
vesicle localization
|
GO:0051648 |
26 |
0.110
|
Mouse Rat Worm |
|
|
response to starvation
|
GO:0042594 |
59 |
0.109
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.109
|
Worm |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.108
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.108
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.107
|
Worm |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.106
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.105
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.105
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.104
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.103
|
Worm Fly |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.101
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.101
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.100
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.100
|
Worm Fly |
|
|
growth
|
GO:0040007 |
202 |
0.100
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.100
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.100
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.099
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.099
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.098
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.097
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.096
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.096
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.096
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.095
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.093
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.093
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.092
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.090
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.090
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.088
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.088
|
Worm Fly |
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.088
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.088
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.088
|
Fly |
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.088
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.087
|
Fly |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.087
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.087
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.085
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.085
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.084
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.084
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.084
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.083
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.081
|
Worm |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.081
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.080
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.080
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.080
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.080
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.079
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.079
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.079
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.078
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.077
|
Fly |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.077
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.076
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.076
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.073
|
Fly |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.073
|
Worm |
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.073
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.073
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.072
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.072
|
Fly |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.071
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.071
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.071
|
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.071
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.070
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.070
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.070
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.069
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.069
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.069
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.069
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.068
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.068
|
|
|
|
mitotic spindle elongation
|
GO:0000022 |
4 |
0.068
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.068
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.067
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.067
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.067
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.067
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.067
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.067
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.067
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.066
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.066
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.066
|
Fly |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.066
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.066
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.064
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.064
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.063
|
|
|
|
insulin secretion
|
GO:0030073 |
39 |
0.063
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.063
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.063
|
|
|
|
axon extension
|
GO:0048675 |
13 |
0.062
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.062
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.061
|
Fly |
|
|
macroautophagy
|
GO:0016236 |
39 |
0.061
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.061
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.061
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.061
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.060
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.060
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.059
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.059
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.059
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.059
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.058
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.058
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.058
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.057
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.057
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.056
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.056
|
Worm |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.056
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.056
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.055
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.055
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.054
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.054
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.054
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.053
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.053
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.053
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.053
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.053
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.053
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.053
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.052
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.052
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.052
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.052
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.052
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.052
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.051
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.051
|
Worm Fly |
|
|
negative regulation of microtubule polymerization or depolymerization
|
GO:0031111 |
17 |
0.051
|
|
|
|
regulation of odontogenesis
|
GO:0042481 |
4 |
0.051
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.051
|
|
|
|
spindle elongation
|
GO:0051231 |
4 |
0.050
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.049
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.049
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.049
|
Fly |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.049
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.049
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.048
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.048
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.048
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.048
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.047
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.046
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.046
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.046
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.045
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.045
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.044
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.044
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.043
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.043
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.043
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.042
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.042
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.042
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.041
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.041
|
Worm Fly |
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.040
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.040
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.040
|
Worm Fly |
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.040
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.039
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.039
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.039
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.039
|
Fly |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.038
|
|
|
|
intermediate filament based process
|
GO:0045103 |
17 |
0.038
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.038
|
Worm |
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.038
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.037
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.037
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.037
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.037
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.037
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.036
|
Fly |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.036
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.036
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.036
|
Worm Fly |
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.035
|
|
|
|
establishment of spindle orientation
|
GO:0051294 |
9 |
0.035
|
Worm |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.035
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.034
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.034
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.034
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
15 |
0.034
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.033
|
Worm Fly |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.033
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.033
|
|
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
2 |
0.033
|
|
|
|
establishment of protein localization to mitochondrion
|
GO:0072655 |
22 |
0.033
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.033
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.033
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.033
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.032
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.032
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.031
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.031
|
|
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
17 |
0.031
|
|
|
|
negative regulation of carbohydrate metabolic process
|
GO:0045912 |
20 |
0.031
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.031
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.031
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.031
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.031
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.030
|
Fly |
|
|
spindle organization
|
GO:0007051 |
53 |
0.030
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.030
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.030
|
|
|
|
mitochondrial respiratory chain complex assembly
|
GO:0033108 |
23 |
0.030
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.030
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.030
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.030
|
|
|
|
glutamine family amino acid metabolic process
|
GO:0009064 |
17 |
0.029
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.029
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.029
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.029
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.029
|
|
|
|
phagocytosis
|
GO:0006909 |
42 |
0.029
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.029
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.029
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
27 |
0.029
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.028
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.028
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.028
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.028
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.028
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.028
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.028
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.028
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.027
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.027
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.027
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.027
|
Worm |
|
|
meiosis i
|
GO:0007127 |
4 |
0.027
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.027
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.027
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.027
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.027
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.027
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
16 |
0.027
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.026
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.026
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.026
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.026
|
|
|
|
microtubule depolymerization
|
GO:0007019 |
18 |
0.026
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.026
|
Fly |
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.025
|
|
|
|
negative regulation of microtubule depolymerization
|
GO:0007026 |
12 |
0.025
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.025
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.025
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.025
|
Worm Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.025
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.025
|
|
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.025
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.025
|
Fly |
|
|
vesicle organization
|
GO:0016050 |
62 |
0.025
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.024
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.024
|
|
|
|
apoptotic cell clearance
|
GO:0043277 |
12 |
0.024
|
|
|
|
microtubule anchoring
|
GO:0034453 |
24 |
0.024
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.024
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.024
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.023
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.023
|
Fly |
|
|
response to other organism
|
GO:0051707 |
261 |
0.023
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.023
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.023
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.023
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.023
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.023
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.023
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.023
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.023
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.023
|
Worm |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.023
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.023
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.022
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.022
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.022
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.022
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.022
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.022
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
20 |
0.022
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.022
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.022
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.022
|
|
