Homo sapiens

266 known processes

KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

(Aliases: PBT,CD117,C-Kit,SCFR)

KIT biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amine metabolic process GO:0033238 11 0.937
amine metabolic process GO:0009308 44 0.912
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.909
cellular amino acid metabolic process GO:0006520 116 0.846
regulation of map kinase activity GO:0043405 108 0.830
cellular ketone metabolic process GO:0042180 80 0.821
regulation of cellular ketone metabolic process GO:0010565 50 0.810
regulation of kinase activity GO:0043549 314 0.809
positive regulation of cellular amine metabolic process GO:0033240 7 0.801
regulation of cellular amino acid metabolic process GO:0006521 6 0.794
regulation of transferase activity GO:0051338 355 0.738
regulation of mapk cascade GO:0043408 262 0.727
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.723
ras protein signal transduction GO:0007265 73 0.718
regulation of cell differentiation GO:0045595 393 0.709
Human Rat Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.662
cellular amine metabolic process GO:0044106 41 0.646
regulation of protein serine threonine kinase activity GO:0071900 179 0.634
myeloid cell differentiation GO:0030099 117 0.630
Mouse
regulation of protein kinase activity GO:0045859 289 0.585
positive regulation of kinase activity GO:0033674 204 0.562
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.551
positive regulation of developmental process GO:0051094 314 0.516
Human Rat
small gtpase mediated signal transduction GO:0007264 78 0.512
negative regulation of apoptotic process GO:0043066 316 0.507
Human Fly
peptidyl tyrosine modification GO:0018212 170 0.491
mapk cascade GO:0000165 288 0.488
leukocyte differentiation GO:0002521 98 0.469
Mouse
positive regulation of protein phosphorylation GO:0001934 313 0.460
peptidyl tyrosine phosphorylation GO:0018108 170 0.456
positive regulation of cell proliferation GO:0008284 301 0.436
Human Mouse Rat
positive regulation of cell differentiation GO:0045597 211 0.400
Rat
hemopoiesis GO:0030097 180 0.395
Human Mouse Fly
negative regulation of immune system process GO:0002683 136 0.378
enzyme linked receptor protein signaling pathway GO:0007167 303 0.364
hematopoietic or lymphoid organ development GO:0048534 186 0.361
Human Mouse Fly
epithelium development GO:0060429 227 0.354
Zebrafish Mouse Fly
immune system development GO:0002520 195 0.351
Human Mouse Fly
positive regulation of immune system process GO:0002684 283 0.351
cell activation GO:0001775 213 0.349
cellular response to endogenous stimulus GO:0071495 336 0.347
Human Mouse Fly
negative regulation of cell death GO:0060548 345 0.343
Human Mouse Fly
positive regulation of phosphorylation GO:0042327 394 0.341
lipid metabolic process GO:0006629 381 0.335
Human Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.313
Human
neural crest cell development GO:0014032 3 0.295
negative regulation of programmed cell death GO:0043069 321 0.294
Human Mouse Fly
glycerolipid metabolic process GO:0046486 107 0.293
Human
myeloid leukocyte differentiation GO:0002573 60 0.292
Mouse
positive regulation of map kinase activity GO:0043406 80 0.287
phosphatidylinositol mediated signaling GO:0048015 55 0.286
Human
biological adhesion GO:0022610 331 0.278
Human Mouse
rho protein signal transduction GO:0007266 26 0.262
regulation of cell migration GO:0030334 289 0.255
Human Rat
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.250
regulation of small gtpase mediated signal transduction GO:0051056 156 0.246
leukocyte activation GO:0045321 164 0.245
gtp metabolic process GO:0046039 239 0.241
positive regulation of transferase activity GO:0051347 227 0.237
regulation of myeloid cell differentiation GO:0045637 81 0.236
neural crest cell migration GO:0001755 2 0.234
cranial nerve development GO:0021545 4 0.233
regulation of locomotion GO:0040012 329 0.232
Human Rat
lipid biosynthetic process GO:0008610 177 0.232
cell type specific apoptotic process GO:0097285 125 0.226
Human Zebrafish
response to organic cyclic compound GO:0014070 204 0.225
regulation of leukocyte proliferation GO:0070663 67 0.222
homeostasis of number of cells GO:0048872 40 0.218
Mouse Fly
regulation of leukocyte differentiation GO:1902105 61 0.216
regulation of stress activated mapk cascade GO:0032872 84 0.207
Human
circulatory system development GO:0072359 262 0.205
Human
signal transduction by phosphorylation GO:0023014 297 0.204
response to oxygen containing compound GO:1901700 369 0.201
Fly
regulation of jnk cascade GO:0046328 73 0.200
Human
positive regulation of dna replication GO:0045740 35 0.197
Human
cell development GO:0048468 328 0.194
Mouse Rat Fly
extrinsic apoptotic signaling pathway GO:0097191 119 0.189
developmental programmed cell death GO:0010623 3 0.185
Mouse
glycosyl compound catabolic process GO:1901658 413 0.182
negative regulation of homeostatic process GO:0032845 59 0.179
cellular lipid metabolic process GO:0044255 303 0.179
Human Mouse
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.179
Human
positive regulation of locomotion GO:0040017 186 0.176
Human Rat
gtp catabolic process GO:0006184 237 0.176
post embryonic development GO:0009791 2 0.176
Fly
regulation of cell activation GO:0050865 125 0.164
Human
nucleotide catabolic process GO:0009166 408 0.164
protein autophosphorylation GO:0046777 123 0.162
stress activated protein kinase signaling cascade GO:0031098 94 0.162
Human
embryonic hemopoiesis GO:0035162 4 0.161
Mouse Fly
photoreceptor cell differentiation GO:0046530 2 0.156
negative regulation of developmental process GO:0051093 247 0.155
Rat
epithelial cell differentiation GO:0030855 141 0.152
Zebrafish Mouse Fly
cellular cation homeostasis GO:0030003 163 0.141
Human
cation transport GO:0006812 331 0.140
positive regulation of cell motility GO:2000147 177 0.138
Human Rat
stem cell differentiation GO:0048863 93 0.137
Human Mouse Rat
glycerophospholipid metabolic process GO:0006650 84 0.137
Human
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.134
Human
regulation of ras protein signal transduction GO:0046578 155 0.132
positive regulation of small gtpase mediated signal transduction GO:0051057 12 0.129
startle response GO:0001964 3 0.128
endothelial cell migration GO:0043542 86 0.127
Human
apoptotic signaling pathway GO:0097190 268 0.127
phosphatidylinositol metabolic process GO:0046488 53 0.126
Human
calcium ion homeostasis GO:0055074 122 0.125
Human
cellular ion homeostasis GO:0006873 168 0.125
Human
leukocyte proliferation GO:0070661 74 0.124
positive regulation of jnk cascade GO:0046330 52 0.122
Human
activation of mapk activity GO:0000187 45 0.122
ameboidal type cell migration GO:0001667 135 0.120
Human Zebrafish Mouse Fly
inositol lipid mediated signaling GO:0048017 55 0.120
Human
motor neuron axon guidance GO:0008045 2 0.119
regulation of erk1 and erk2 cascade GO:0070372 99 0.119
Human
response to other organism GO:0051707 261 0.119
Fly
response to biotic stimulus GO:0009607 276 0.116
Fly
male sex differentiation GO:0046661 25 0.116
determination of adult lifespan GO:0008340 2 0.115
oogenesis GO:0048477 2 0.115
Fly
negative regulation of cell proliferation GO:0008285 228 0.114
regulation of cell motility GO:2000145 299 0.112
Human Rat
cation homeostasis GO:0055080 189 0.110
Human
ribonucleoside triphosphate catabolic process GO:0009203 391 0.110
ribonucleotide catabolic process GO:0009261 405 0.108
male genitalia development GO:0030539 1 0.108
Fly
regulation of behavior GO:0050795 82 0.107
Human
positive regulation of protein kinase activity GO:0045860 190 0.107
regulation of neuron differentiation GO:0045664 70 0.107
positive regulation of endothelial cell migration GO:0010595 39 0.106
Human
jnk cascade GO:0007254 80 0.106
Human
positive regulation of leukocyte proliferation GO:0070665 48 0.105
chemotaxis GO:0006935 157 0.104
positive regulation of cell migration GO:0030335 172 0.104
Human Rat
purine nucleotide catabolic process GO:0006195 405 0.104
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.102
Human
cell morphogenesis GO:0000902 296 0.101
Human Mouse Fly
development of primary male sexual characteristics GO:0046546 23 0.101
regulation of dna metabolic process GO:0051052 153 0.101
Human
cellular response to oxygen containing compound GO:1901701 276 0.101
Fly
female gamete generation GO:0007292 2 0.100
Fly
blood vessel morphogenesis GO:0048514 162 0.100
Human
regulation of cell development GO:0060284 161 0.098
Rat
activation of protein kinase activity GO:0032147 90 0.097
negative regulation of leukocyte apoptotic process GO:2000107 16 0.097
stress activated mapk cascade GO:0051403 93 0.097
Human
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.096
Human
multicellular organismal aging GO:0010259 3 0.095
organophosphate biosynthetic process GO:0090407 163 0.095
mesenchyme development GO:0060485 59 0.094
cellular metal ion homeostasis GO:0006875 146 0.093
Human
protein localization to organelle GO:0033365 280 0.092
purine ribonucleoside metabolic process GO:0046128 437 0.092
divalent inorganic cation homeostasis GO:0072507 136 0.090
Human
cell fate determination GO:0001709 3 0.090
ribonucleoside catabolic process GO:0042454 406 0.090
g protein coupled receptor signaling pathway GO:0007186 207 0.089
embryonic organ development GO:0048568 36 0.088
Mouse Fly
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 3 0.088
Human
innate immune response GO:0045087 178 0.088
Fly
rap protein signal transduction GO:0032486 7 0.087
positive regulation of protein kinase b signaling GO:0051897 42 0.087
mast cell degranulation GO:0043303 4 0.087
cellular response to nitrogen compound GO:1901699 144 0.086
Fly
nucleoside triphosphate catabolic process GO:0009143 394 0.086
blastoderm segmentation GO:0007350 2 0.086
regulation of developmental pigmentation GO:0048070 2 0.085
Mouse
reproductive process GO:0022414 106 0.085
positive regulation of catabolic process GO:0009896 310 0.084
regulation of reactive oxygen species metabolic process GO:2000377 41 0.084
response to nitrogen compound GO:1901698 184 0.084
Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.084
segmentation GO:0035282 4 0.083
ion homeostasis GO:0050801 230 0.083
Human
positive regulation of cell adhesion GO:0045785 84 0.083
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.082
associative learning GO:0008306 1 0.081
Rat
regulation of purine nucleotide metabolic process GO:1900542 264 0.080
single organismal cell cell adhesion GO:0016337 148 0.079
Human Mouse
positive regulation of transport GO:0051050 336 0.079
Human
phosphatidylinositol 3 phosphate biosynthetic process GO:0036092 3 0.079
single organism reproductive process GO:0044702 98 0.078
t cell activation GO:0042110 99 0.078
Mouse
positive regulation of tyrosine phosphorylation of stat5 protein GO:0042523 11 0.077
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.076
cell projection organization GO:0030030 252 0.076
Mouse Rat Fly
nerve development GO:0021675 4 0.075
generation of neurons GO:0048699 152 0.075
Rat
regulation of dna replication GO:0006275 68 0.075
Human
regulation of leukocyte apoptotic process GO:2000106 25 0.074
cytokine mediated signaling pathway GO:0019221 109 0.074
cellular calcium ion homeostasis GO:0006874 117 0.073
Human
glycerolipid biosynthetic process GO:0045017 51 0.073
cellular response to organonitrogen compound GO:0071417 124 0.073
Fly
positive regulation of secretion GO:0051047 116 0.072
Human
nucleoside catabolic process GO:0009164 408 0.071
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.071
mitotic cell cycle GO:0000278 326 0.070
Fly
neuron projection development GO:0031175 106 0.070
cellular response to organic cyclic compound GO:0071407 127 0.070
actin cytoskeleton organization GO:0030036 207 0.069
lymphocyte activation GO:0046649 133 0.069
Mouse
positive regulation of cellular component movement GO:0051272 181 0.069
Human Rat
regulation of cell cycle GO:0051726 393 0.068
morphogenesis of embryonic epithelium GO:0016331 4 0.068
regulation of establishment of protein localization GO:0070201 242 0.067
Human
positive regulation of cell development GO:0010720 92 0.067
Rat
regulation of nucleotide catabolic process GO:0030811 205 0.066
compound eye development GO:0048749 1 0.066
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.066
Human
purine nucleoside catabolic process GO:0006152 398 0.066
actin filament based process GO:0030029 224 0.066
melanocyte differentiation GO:0030318 2 0.065
Zebrafish Mouse
neurogenesis GO:0022008 169 0.065
Rat
epithelial cell proliferation GO:0050673 128 0.065
Human Rat
response to lipid GO:0033993 206 0.065
reproductive system development GO:0061458 56 0.064
regulation of response to external stimulus GO:0032101 222 0.064
Human
mesenchymal cell differentiation GO:0048762 52 0.063
regulation of cell adhesion GO:0030155 166 0.063
Human
secretion GO:0046903 254 0.063
positive regulation of jak stat cascade GO:0046427 35 0.063
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.062
secretion by cell GO:0032940 226 0.062
guanosine containing compound catabolic process GO:1901069 239 0.061
cell chemotaxis GO:0060326 112 0.061
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.061
response to estrogen GO:0043627 47 0.060
positive regulation of leukocyte differentiation GO:1902107 37 0.060
cellular divalent inorganic cation homeostasis GO:0072503 128 0.060
Human
guanosine containing compound metabolic process GO:1901068 244 0.059
response to hormone GO:0009725 175 0.059
Mouse Fly
actin filament organization GO:0007015 128 0.059
Fly
axon regeneration GO:0031103 1 0.059
regulation of gtp catabolic process GO:0033124 180 0.059
cellular component morphogenesis GO:0032989 314 0.058
Human Mouse Fly
immune response GO:0006955 307 0.058
purine nucleoside triphosphate catabolic process GO:0009146 392 0.057
signal transduction in absence of ligand GO:0038034 22 0.056
response to oxidative stress GO:0006979 121 0.056
defense response GO:0006952 315 0.055
Mouse Fly
anatomical structure formation involved in morphogenesis GO:0048646 284 0.055
Human
regulation of cellular response to stress GO:0080135 244 0.055
Human
regulation of rho protein signal transduction GO:0035023 79 0.055
regulation of immune response GO:0050776 201 0.055
embryo development GO:0009790 123 0.054
Mouse Fly
regulation of nucleoside metabolic process GO:0009118 209 0.054
regulation of secretion by cell GO:1903530 177 0.054
Human
regulation of myeloid leukocyte differentiation GO:0002761 39 0.053
antimicrobial humoral response GO:0019730 26 0.053
Fly
reactive oxygen species metabolic process GO:0072593 75 0.053
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.051
response to bacterium GO:0009617 144 0.051
response to external biotic stimulus GO:0043207 261 0.050
Fly
microtubule based process GO:0007017 210 0.050
Fly
immune response regulating signaling pathway GO:0002764 97 0.050
astrocyte differentiation GO:0048708 4 0.049
neuron differentiation GO:0030182 138 0.049
response to organonitrogen compound GO:0010243 156 0.049
Fly
exocytosis GO:0006887 71 0.049
regeneration GO:0031099 4 0.049
locomotory behavior GO:0007626 1 0.048
positive regulation of immune response GO:0050778 159 0.048
regulation of epithelial cell proliferation GO:0050678 113 0.048
Human
cardiovascular system development GO:0072358 262 0.048
Human
spermatid development GO:0007286 4 0.048
Mouse
purine containing compound catabolic process GO:0072523 411 0.048
intracellular protein transport GO:0006886 270 0.048
regulation of leukocyte activation GO:0002694 115 0.048
posttranscriptional regulation of gene expression GO:0010608 213 0.047
mitotic cell cycle process GO:1903047 286 0.047
Fly
positive regulation of stress activated mapk cascade GO:0032874 60 0.047
Human
developmental process involved in reproduction GO:0003006 66 0.047
epithelial cell migration GO:0010631 119 0.046
Human Zebrafish Mouse Fly
protein catabolic process GO:0030163 325 0.046
positive regulation of cellular catabolic process GO:0031331 284 0.046
positive regulation of ras gtpase activity GO:0032320 117 0.046
nucleoside triphosphate metabolic process GO:0009141 422 0.046
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.046
reactive nitrogen species metabolic process GO:2001057 3 0.046
phospholipid biosynthetic process GO:0008654 44 0.046
microtubule cytoskeleton organization GO:0000226 176 0.046
Fly
regulation of hormone levels GO:0010817 125 0.045
neurological system process GO:0050877 163 0.045
Mouse Rat
lymphocyte homeostasis GO:0002260 4 0.045
response to estradiol GO:0032355 23 0.045
second messenger mediated signaling GO:0019932 78 0.045
Human
behavior GO:0007610 112 0.045
Human Rat
cell adhesion GO:0007155 325 0.045
Human Mouse
regulation of epithelial cell migration GO:0010632 93 0.044
Human
vesicle mediated transport GO:0016192 371 0.044
divalent inorganic cation transport GO:0072511 158 0.044
regulation of cellular component movement GO:0051270 334 0.044
Human Rat
regulation of homeostatic process GO:0032844 121 0.043
metal ion homeostasis GO:0055065 169 0.043
Human
response to acid chemical GO:0001101 66 0.043
negative regulation of cell differentiation GO:0045596 171 0.043
Rat
mesenchymal cell development GO:0014031 50 0.043
cytokine secretion GO:0050663 64 0.042
Human
regulation of mitotic cell cycle GO:0007346 189 0.042
positive regulation of cytoplasmic transport GO:1903651 82 0.042
positive regulation of mapk cascade GO:0043410 190 0.042
negative regulation of transport GO:0051051 176 0.042
metal ion transport GO:0030001 272 0.041
regulation of system process GO:0044057 101 0.041
regulation of nucleotide metabolic process GO:0006140 269 0.041
regulation of purine nucleotide catabolic process GO:0033121 205 0.041
cellular chemical homeostasis GO:0055082 180 0.041
Human
regulation of tyrosine phosphorylation of stat5 protein GO:0042522 12 0.041
single organism cellular localization GO:1902580 332 0.040
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.040
nervous system development GO:0007399 293 0.040
Rat Fly
positive regulation of rap gtpase activity GO:0032854 8 0.039
regulation of neurogenesis GO:0050767 82 0.039
Rat
regulation of protein catabolic process GO:0042176 155 0.039
regulation of gtpase activity GO:0043087 180 0.039
neuron projection regeneration GO:0031102 1 0.038
neuromuscular junction development GO:0007528 3 0.038
negative regulation of myeloid cell apoptotic process GO:0033033 4 0.038
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 16 0.038
nucleoside phosphate catabolic process GO:1901292 412 0.038
regulation of ion transport GO:0043269 189 0.038
phosphatidylinositol biosynthetic process GO:0006661 25 0.037
negative regulation of protein metabolic process GO:0051248 391 0.037
positive regulation of cytokine production GO:0001819 167 0.037
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.037
negative regulation of leukocyte differentiation GO:1902106 24 0.037
positive regulation of neuron projection development GO:0010976 34 0.037
positive regulation of programmed cell death GO:0043068 249 0.036
organophosphate catabolic process GO:0046434 430 0.036
positive regulation of protein transport GO:0051222 135 0.036
Human
neuron development GO:0048666 113 0.036
rhythmic behavior GO:0007622 2 0.036
regulation of cell projection organization GO:0031344 107 0.036
Rat
reactive oxygen species biosynthetic process GO:1903409 4 0.036
regulation of angiogenesis GO:0045765 92 0.036
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.036
positive regulation of cellular component organization GO:0051130 376 0.036
Human Rat
peripheral nervous system development GO:0007422 2 0.036
regulation of t cell activation GO:0050863 77 0.036
protein kinase b signaling GO:0043491 69 0.035
negative regulation of protein phosphorylation GO:0001933 140 0.035
regulation of endothelial cell migration GO:0010594 67 0.035
Human
regulation of lymphocyte activation GO:0051249 103 0.034
negative regulation of axon extension GO:0030517 2 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
immune effector process GO:0002252 159 0.034
ephrin receptor signaling pathway GO:0048013 15 0.034
oocyte differentiation GO:0009994 2 0.034
positive regulation of neurogenesis GO:0050769 49 0.034
Rat
regulation of protein kinase b signaling GO:0051896 61 0.034
negative regulation of catalytic activity GO:0043086 335 0.034
t cell differentiation in thymus GO:0033077 4 0.034
behavioral response to ethanol GO:0048149 2 0.034
positive regulation of mast cell activation GO:0033005 2 0.033
regulation of proteolysis GO:0030162 293 0.033
regulation of vasculature development GO:1901342 97 0.033
Human
regulation of microtubule based process GO:0032886 74 0.033
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.033
leukocyte apoptotic process GO:0071887 31 0.033
regulation of intracellular transport GO:0032386 195 0.033
positive regulation of rac gtpase activity GO:0032855 31 0.033
response to inorganic substance GO:0010035 127 0.033
cytoplasmic transport GO:0016482 379 0.033
cellular response to hormone stimulus GO:0032870 125 0.032
Mouse Fly
growth GO:0040007 202 0.032
positive regulation of apoptotic process GO:0043065 246 0.032
regulation of cytokine production GO:0001817 232 0.032
Human
negative regulation of intracellular signal transduction GO:1902532 183 0.032
cellular response to abiotic stimulus GO:0071214 117 0.032
regulation of growth GO:0040008 165 0.032
regulation of translation GO:0006417 89 0.032
positive regulation of myeloid cell differentiation GO:0045639 39 0.032
positive regulation of rho gtpase activity GO:0032321 56 0.032
regulation of neuron apoptotic process GO:0043523 35 0.032
keratinization GO:0031424 2 0.031
calcium ion transport GO:0006816 147 0.031
negative regulation of mitotic cell cycle GO:0045930 102 0.031
cell junction organization GO:0034330 79 0.031
Human
system process GO:0003008 349 0.031
Zebrafish Mouse Rat
neuron fate commitment GO:0048663 2 0.031
positive regulation of response to external stimulus GO:0032103 88 0.031
Human
regulation of neuron projection development GO:0010975 57 0.031
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.031
Human
regulation of cell substrate adhesion GO:0010810 68 0.031
Human
negative regulation of cell activation GO:0050866 33 0.031
Human
male gonad development GO:0008584 23 0.031
positive regulation of lipase activity GO:0060193 28 0.031
Human
reproductive structure development GO:0048608 55 0.031
tongue development GO:0043586 1 0.031
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.031
sex differentiation GO:0007548 45 0.031
g1 s transition of mitotic cell cycle GO:0000082 78 0.031
regulation of protein transport GO:0051223 213 0.031
Human
immune response activating signal transduction GO:0002757 90 0.031
oocyte development GO:0048599 1 0.030
positive regulation of epithelial cell proliferation GO:0050679 65 0.030
Human
regulation of glial cell differentiation GO:0045685 3 0.030
regulation of anatomical structure morphogenesis GO:0022603 286 0.030
Human Mouse Fly
cell cell signaling GO:0007267 155 0.030
Rat
regulation of mast cell degranulation GO:0043304 3 0.030
vegf activated platelet derived growth factor receptor signaling pathway GO:0038086 3 0.030
Human
glycerophospholipid biosynthetic process GO:0046474 40 0.030
cell division GO:0051301 168 0.030
Rat
hair follicle morphogenesis GO:0031069 2 0.030
regulation of synaptic plasticity GO:0048167 3 0.029
Rat
regulation of cellular component biogenesis GO:0044087 281 0.029
Human Rat
response to cytokine GO:0034097 232 0.029
circulatory system process GO:0003013 113 0.029
protein targeting GO:0006605 187 0.029
regulation of ras gtpase activity GO:0032318 128 0.029
hematopoietic progenitor cell differentiation GO:0002244 38 0.029
Mouse
sensory perception of pain GO:0019233 4 0.029
nuclear transport GO:0051169 179 0.029
cytokine production GO:0001816 247 0.028
inflammatory response GO:0006954 79 0.028
Mouse
positive regulation of dna metabolic process GO:0051054 73 0.028
Human
cellular macromolecular complex assembly GO:0034622 324 0.028
positive regulation of nucleoside metabolic process GO:0045979 186 0.028
regulation of nervous system development GO:0051960 88 0.028
Rat
positive regulation of gtp catabolic process GO:0033126 166 0.028
cd8 positive alpha beta t cell activation GO:0036037 3 0.028
regulation of cell morphogenesis GO:0022604 153 0.028
Human Mouse Fly
cell substrate adhesion GO:0031589 132 0.028
Human
cell matrix adhesion GO:0007160 85 0.028
Human
negative regulation of cell migration GO:0030336 102 0.027
actin mediated cell contraction GO:0070252 12 0.027
establishment of protein localization to organelle GO:0072594 172 0.027
regulation of actin filament based process GO:0032970 141 0.027
positive regulation of cell death GO:0010942 263 0.027
sequestering of metal ion GO:0051238 24 0.027
cell projection morphogenesis GO:0048858 129 0.027
regulation of lymphocyte proliferation GO:0050670 64 0.027
rac protein signal transduction GO:0016601 12 0.027
cellular response to lipid GO:0071396 127 0.027
positive regulation of cell projection organization GO:0031346 64 0.027
Rat
cell projection assembly GO:0030031 126 0.027
Mouse Rat Fly
negative regulation of locomotion GO:0040013 118 0.027
dephosphorylation GO:0016311 209 0.027
Human
negative regulation of alpha beta t cell activation GO:0046636 3 0.027
protein import GO:0017038 130 0.026
negative regulation of secretion GO:0051048 58 0.026
response to abiotic stimulus GO:0009628 336 0.026
Mouse Rat
positive regulation of neuron differentiation GO:0045666 40 0.026
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.026
regulation of metal ion transport GO:0010959 120 0.026
stem cell division GO:0017145 2 0.026
Rat
regulation of chemotaxis GO:0050920 74 0.026
Human
regulation of protein localization GO:0032880 296 0.026
Human
regulation of response to wounding GO:1903034 101 0.026
Human
regulation of rho gtpase activity GO:0032319 66 0.026
mononuclear cell proliferation GO:0032943 71 0.026
negative regulation of cytokine production GO:0001818 82 0.026
neuron death GO:0070997 65 0.025
humoral immune response GO:0006959 49 0.025
Fly
chemical homeostasis GO:0048878 306 0.025
Human
response to axon injury GO:0048678 1 0.025
cell cell junction maintenance GO:0045217 4 0.025
Human
positive regulation of leukocyte activation GO:0002696 80 0.025
translation GO:0006412 132 0.025
regulation of cell cycle g1 s phase transition GO:1902806 42 0.025
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.025
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.025
positive regulation of nucleotide catabolic process GO:0030813 185 0.025
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.024
inner ear morphogenesis GO:0042472 4 0.024
regulation of epithelial cell differentiation GO:0030856 24 0.024
tyrosine phosphorylation of stat5 protein GO:0042506 13 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.024
taxis GO:0042330 157 0.024
response to steroid hormone GO:0048545 80 0.024
calcium mediated signaling using intracellular calcium source GO:0035584 7 0.024
Human
regulation of dendritic cell apoptotic process GO:2000668 4 0.024
response to wounding GO:0009611 168 0.024
Human
jak stat cascade GO:0007259 46 0.024
regulation of neural precursor cell proliferation GO:2000177 4 0.024
cerebral cortex cell migration GO:0021795 3 0.024
erk1 and erk2 cascade GO:0070371 104 0.024
Human
lipid modification GO:0030258 84 0.023
Human
negative regulation of cell cycle GO:0045786 193 0.023
tyrosine phosphorylation of stat protein GO:0007260 33 0.023
regulation of autophagy GO:0010506 52 0.023
cellular macromolecule catabolic process GO:0044265 380 0.023
cytosolic calcium ion homeostasis GO:0051480 89 0.023
Human
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.023
cellular homeostasis GO:0019725 196 0.023
Human
phospholipid metabolic process GO:0006644 99 0.023
Human
carboxylic acid biosynthetic process GO:0046394 97 0.023
embryonic placenta development GO:0001892 1 0.023
negative regulation of cell development GO:0010721 48 0.023
single organism carbohydrate metabolic process GO:0044723 193 0.023

KIT disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.117
disease of cellular proliferation DOID:14566 174 0.117
organ system cancer DOID:0050686 164 0.055
musculoskeletal system disease DOID:17 223 0.034
connective tissue disease DOID:65 109 0.034
disease of metabolism DOID:0014667 295 0.027
gastrointestinal system cancer DOID:3119 52 0.024