Homo sapiens

33 known processes

KPNB1

karyopherin (importin) beta 1

(Aliases: IPOB,MGC2155,MGC2156,Impnb,NTF97,IMB1,MGC2157,IPO1)

KPNB1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nls bearing protein import into nucleus GO:0006607 2 1.000
Fly
protein targeting to nucleus GO:0044744 104 0.998
cytoplasmic transport GO:0016482 379 0.998
single organism cellular localization GO:1902580 332 0.997
nucleocytoplasmic transport GO:0006913 176 0.997
nucleus organization GO:0006997 28 0.996
Yeast
intracellular protein transport GO:0006886 270 0.996
protein localization to nucleus GO:0034504 136 0.992
nuclear transport GO:0051169 179 0.990
protein import into nucleus GO:0006606 104 0.989
rna transport GO:0050658 39 0.987
establishment of protein localization to organelle GO:0072594 172 0.984
protein targeting GO:0006605 187 0.981
protein import GO:0017038 130 0.981
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.979
Fly
single organism nuclear import GO:1902593 104 0.975
nuclear import GO:0051170 106 0.975
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.947
protein localization to organelle GO:0033365 280 0.943
positive regulation of protein transport GO:0051222 135 0.926
Fly
establishment of rna localization GO:0051236 39 0.919
regulation of protein localization GO:0032880 296 0.904
Fly
positive regulation of intracellular protein transport GO:0090316 76 0.882
Fly
nuclear pore organization GO:0006999 10 0.881
Yeast
nuclear export GO:0051168 69 0.878
regulation of nucleocytoplasmic transport GO:0046822 98 0.878
Fly
smad protein import into nucleus GO:0007184 13 0.876
enzyme linked receptor protein signaling pathway GO:0007167 303 0.857
positive regulation of cytoplasmic transport GO:1903651 82 0.848
Fly
regulation of cytoplasmic transport GO:1903649 149 0.826
Fly
positive regulation of protein import into nucleus GO:0042307 46 0.792
Fly
establishment of ribosome localization GO:0033753 4 0.779
rna localization GO:0006403 41 0.764
regulation of protein transport GO:0051223 213 0.754
Fly
regulation of protein import into nucleus GO:0042306 78 0.753
Fly
mitotic cell cycle GO:0000278 326 0.742
Worm Fly
nucleic acid transport GO:0050657 39 0.733
regulation of intracellular protein transport GO:0033157 123 0.729
Fly
nucleobase containing compound transport GO:0015931 51 0.680
positive regulation of intracellular transport GO:0032388 104 0.649
Fly
nuclear pore complex assembly GO:0051292 7 0.619
Yeast
rna export from nucleus GO:0006405 33 0.561
positive regulation of nfat protein import into nucleus GO:0051533 3 0.558
Fly
ribosomal protein import into nucleus GO:0006610 2 0.543
post embryonic development GO:0009791 2 0.541
regulation of intracellular transport GO:0032386 195 0.513
Fly
cellular macromolecular complex assembly GO:0034622 324 0.510
Yeast Fly
regulation of establishment of protein localization GO:0070201 242 0.493
Fly
positive regulation of transport GO:0051050 336 0.483
Fly
regulation of mitotic cell cycle GO:0007346 189 0.479
ribonucleoprotein complex export from nucleus GO:0071426 4 0.464
female gamete generation GO:0007292 2 0.459
Fly
regulation of protein localization to nucleus GO:1900180 85 0.445
Fly
regulation of protein targeting GO:1903533 91 0.437
Fly
mitotic cell cycle process GO:1903047 286 0.423
Worm Fly
chromatin modification GO:0016568 298 0.416
cellular response to growth factor stimulus GO:0071363 197 0.403
posttranscriptional regulation of gene expression GO:0010608 213 0.344
protein export from nucleus GO:0006611 29 0.341
meiosis i GO:0007127 4 0.298
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 4 0.290
positive regulation of cellular component organization GO:0051130 376 0.284
neurogenesis GO:0022008 169 0.268
regulation of chromosome segregation GO:0051983 44 0.264
oogenesis GO:0048477 2 0.249
Fly
signal transduction by phosphorylation GO:0023014 297 0.223
regulation of peptidase activity GO:0052547 180 0.217
mapk cascade GO:0000165 288 0.213
sister chromatid segregation GO:0000819 54 0.211
regulation of cell cycle GO:0051726 393 0.211
ribonucleoprotein complex subunit organization GO:0071826 81 0.211
response to growth factor GO:0070848 205 0.207
organelle fission GO:0048285 149 0.188
Fly
secretion GO:0046903 254 0.187
nitrogen compound transport GO:0071705 191 0.180
negative regulation of programmed cell death GO:0043069 321 0.180
ribosomal large subunit export from nucleus GO:0000055 3 0.178
centrosome organization GO:0051297 58 0.176
modification dependent protein catabolic process GO:0019941 209 0.172
ribonucleoprotein complex localization GO:0071166 4 0.172
cellular response to endogenous stimulus GO:0071495 336 0.169
cellular response to cytokine stimulus GO:0071345 181 0.169
microtubule cytoskeleton organization GO:0000226 176 0.159
Worm
ribosome localization GO:0033750 4 0.152
positive regulation of transcription factor import into nucleus GO:0042993 25 0.145
Fly
transcription factor import into nucleus GO:0042991 40 0.145
Fly
regulation of nucleoside metabolic process GO:0009118 209 0.145
Yeast
nervous system development GO:0007399 293 0.141
modification dependent macromolecule catabolic process GO:0043632 212 0.140
rna interference GO:0016246 4 0.138
cell division GO:0051301 168 0.135
chromatin organization GO:0006325 351 0.133
single organism reproductive process GO:0044702 98 0.127
Fly
regulation of gene expression epigenetic GO:0040029 73 0.125
positive regulation of protein localization to nucleus GO:1900182 48 0.118
Fly
small gtpase mediated signal transduction GO:0007264 78 0.115
multicellular organismal aging GO:0010259 3 0.113
negative regulation of cell death GO:0060548 345 0.111
embryo development GO:0009790 123 0.110
Worm
ribosomal subunit export from nucleus GO:0000054 4 0.107
nucleosome assembly GO:0006334 50 0.106
mitotic nuclear division GO:0007067 119 0.104
Fly
posttranscriptional gene silencing GO:0016441 25 0.104
taxis GO:0042330 157 0.102
establishment of organelle localization GO:0051656 59 0.099
reproductive structure development GO:0048608 55 0.096
vesicle mediated transport GO:0016192 371 0.095
ras protein signal transduction GO:0007265 73 0.095
regulation of small gtpase mediated signal transduction GO:0051056 156 0.093
Yeast
dna conformation change GO:0071103 113 0.089
mrna transport GO:0051028 30 0.089
peptidyl serine phosphorylation GO:0018105 101 0.089
purine nucleoside triphosphate metabolic process GO:0009144 412 0.087
chromatin remodeling GO:0006338 55 0.084
regulation of response to external stimulus GO:0032101 222 0.082
embryonic morphogenesis GO:0048598 85 0.080
embryo development ending in birth or egg hatching GO:0009792 34 0.077
Worm
reproductive system development GO:0061458 56 0.072
regulation of nucleotide catabolic process GO:0030811 205 0.072
Yeast
gene silencing by rna GO:0031047 26 0.071
negative regulation of transport GO:0051051 176 0.070
gtp catabolic process GO:0006184 237 0.068
pore complex assembly GO:0046931 9 0.067
Yeast
response to abiotic stimulus GO:0009628 336 0.067
chromatin assembly or disassembly GO:0006333 78 0.065
nucleotide catabolic process GO:0009166 408 0.065
regulation of cell division GO:0051302 116 0.062
posttranscriptional gene silencing by rna GO:0035194 25 0.062
mitotic spindle organization GO:0007052 27 0.061
Worm
rna processing GO:0006396 255 0.060
negative regulation of apoptotic process GO:0043066 316 0.060
positive regulation of gtp catabolic process GO:0033126 166 0.060
Yeast
nucleosome organization GO:0034728 66 0.059
mrna export from nucleus GO:0006406 29 0.059
defense response GO:0006952 315 0.058
spindle organization GO:0007051 53 0.058
Worm
endocytosis GO:0006897 159 0.058
positive regulation of catabolic process GO:0009896 310 0.057
Yeast
regeneration GO:0031099 4 0.056
regulation of mitosis GO:0007088 63 0.056
determination of adult lifespan GO:0008340 2 0.056
regulation of transferase activity GO:0051338 355 0.055
ribonucleoprotein complex biogenesis GO:0022613 116 0.055
phagocytosis GO:0006909 42 0.054
oocyte development GO:0048599 1 0.054
spermatid differentiation GO:0048515 4 0.054
positive regulation of nucleotide metabolic process GO:0045981 230 0.054
Yeast
protein catabolic process GO:0030163 325 0.053
cellular amine metabolic process GO:0044106 41 0.053
Yeast
purine ribonucleoside catabolic process GO:0046130 398 0.052
regulation of nucleotide metabolic process GO:0006140 269 0.051
Yeast
cell cycle phase transition GO:0044770 173 0.051
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.048
organic hydroxy compound metabolic process GO:1901615 147 0.048
Yeast
multicellular organismal reproductive process GO:0048609 40 0.048
Fly
regulation of sister chromatid segregation GO:0033045 27 0.047
nuclear division GO:0000280 128 0.047
Fly
regulation of locomotion GO:0040012 329 0.046
regulation of ras protein signal transduction GO:0046578 155 0.046
Yeast
negative regulation of cytoplasmic transport GO:1903650 46 0.046
positive regulation of hydrolase activity GO:0051345 331 0.045
Yeast
negative regulation of growth GO:0045926 97 0.044
muscle structure development GO:0061061 98 0.044
macromolecule methylation GO:0043414 97 0.041
ribonucleoside triphosphate catabolic process GO:0009203 391 0.041
positive regulation of cellular catabolic process GO:0031331 284 0.041
Yeast
centrosome cycle GO:0007098 32 0.040
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.040
covalent chromatin modification GO:0016569 254 0.039
sensory organ development GO:0007423 52 0.039
response to external biotic stimulus GO:0043207 261 0.039
negative regulation of cell cycle GO:0045786 193 0.039
chromatin assembly GO:0031497 61 0.039
segmentation GO:0035282 4 0.038
gtp metabolic process GO:0046039 239 0.038
ribonucleoprotein complex assembly GO:0022618 78 0.038
regulation of purine nucleotide catabolic process GO:0033121 205 0.038
Yeast
cell junction assembly GO:0034329 67 0.037
reproductive process GO:0022414 106 0.037
Fly
negative regulation of developmental process GO:0051093 247 0.037
anterior posterior axis specification embryo GO:0008595 2 0.036
regulation of endopeptidase activity GO:0052548 170 0.036
oocyte differentiation GO:0009994 2 0.036
gene silencing GO:0016458 49 0.036
reproduction GO:0000003 63 0.036
Worm Fly
mrna metabolic process GO:0016071 175 0.035
regulation of cellular amino acid metabolic process GO:0006521 6 0.035
locomotory behavior GO:0007626 1 0.034
response to oxidative stress GO:0006979 121 0.034
organelle assembly GO:0070925 176 0.034
cellular response to oxygen containing compound GO:1901701 276 0.033
embryonic epithelial tube formation GO:0001838 4 0.032
cation transport GO:0006812 331 0.032
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.032
response to oxygen containing compound GO:1901700 369 0.032
amine metabolic process GO:0009308 44 0.032
Yeast
positive regulation of proteolysis GO:0045862 142 0.031
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.031
response to transforming growth factor beta GO:0071559 94 0.031
regulation of cell cycle phase transition GO:1901987 126 0.030
muscle organ development GO:0007517 56 0.030
regulation of dna metabolic process GO:0051052 153 0.030
positive regulation of nucleotide catabolic process GO:0030813 185 0.029
Yeast
regulation of cellular response to growth factor stimulus GO:0090287 76 0.029
negative regulation of protein metabolic process GO:0051248 391 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
cell type specific apoptotic process GO:0097285 125 0.028
organelle localization GO:0051640 84 0.027
protein polyubiquitination GO:0000209 110 0.027
blastoderm segmentation GO:0007350 2 0.025
positive regulation of gtpase activity GO:0043547 166 0.025
Yeast
microtubule based process GO:0007017 210 0.025
Worm
tripartite regional subdivision GO:0007351 2 0.025
regulation of cellular ketone metabolic process GO:0010565 50 0.025
cellular amino acid metabolic process GO:0006520 116 0.025
spermatid development GO:0007286 4 0.025
neural tube formation GO:0001841 3 0.025
positive regulation of apoptotic process GO:0043065 246 0.025
histone methylation GO:0016571 60 0.025
negative regulation of catabolic process GO:0009895 104 0.025
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.025
response to uv GO:0009411 73 0.024
regulation of protein catabolic process GO:0042176 155 0.024
rna 3 end processing GO:0031123 35 0.024
positive regulation of cell division GO:0051781 59 0.023
anatomical structure formation involved in morphogenesis GO:0048646 284 0.023
Fly
cell cell signaling GO:0007267 155 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.023
chordate embryonic development GO:0043009 34 0.023
chemotaxis GO:0006935 157 0.022
cell morphogenesis involved in differentiation GO:0000904 144 0.022
response to oxygen levels GO:0070482 100 0.022
nucleoside triphosphate catabolic process GO:0009143 394 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
glycosyl compound catabolic process GO:1901658 413 0.022
immune effector process GO:0002252 159 0.022
positive regulation of cell cycle GO:0045787 140 0.021
intrinsic apoptotic signaling pathway GO:0097193 127 0.021
regulation of membrane potential GO:0042391 95 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.021
nucleoside triphosphate metabolic process GO:0009141 422 0.021
protein methylation GO:0006479 74 0.021
vasculature development GO:0001944 181 0.020
regulation of protein stability GO:0031647 87 0.020
maturation of 5 8s rrna GO:0000460 8 0.020
microtubule organizing center organization GO:0031023 62 0.020
cellular response to decreased oxygen levels GO:0036294 51 0.020
tube development GO:0035295 125 0.019
endomembrane system organization GO:0010256 196 0.019
regulation of chromosome organization GO:0033044 103 0.019
ribonucleoside triphosphate metabolic process GO:0009199 412 0.019
negative regulation of cell cycle process GO:0010948 121 0.019
positive regulation of mitotic cell cycle GO:0045931 60 0.019
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.019
ubiquitin dependent protein catabolic process GO:0006511 206 0.019
protein folding GO:0006457 38 0.019
anterior posterior axis specification GO:0009948 2 0.019
regulation of binding GO:0051098 111 0.019
centrosome duplication GO:0051298 28 0.018
nfat protein import into nucleus GO:0051531 5 0.018
Fly
neuron projection morphogenesis GO:0048812 50 0.018
regulation of cell cycle process GO:0010564 266 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
developmental growth GO:0048589 48 0.018
developmental process involved in reproduction GO:0003006 66 0.018
Fly
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
Yeast
cellular response to oxidative stress GO:0034599 85 0.018
regulation of cellular amine metabolic process GO:0033238 11 0.018
response to lipid GO:0033993 206 0.018
positive regulation of binding GO:0051099 45 0.017
blastocyst development GO:0001824 3 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
Yeast
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.017
protein autophosphorylation GO:0046777 123 0.017
angiogenesis GO:0001525 147 0.017
neuromuscular junction development GO:0007528 3 0.017
regulation of kinase activity GO:0043549 314 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
regulation of cellular response to stress GO:0080135 244 0.017
regulation of system process GO:0044057 101 0.017
ribonucleotide catabolic process GO:0009261 405 0.017
positive regulation of cell cycle process GO:0090068 106 0.017
cellular protein catabolic process GO:0044257 261 0.017
regulation of proteasomal protein catabolic process GO:0061136 87 0.017
negative regulation of neuron death GO:1901215 32 0.017
response to nitrogen compound GO:1901698 184 0.017
purine ribonucleoside metabolic process GO:0046128 437 0.017
cellular protein complex assembly GO:0043623 188 0.016
Yeast Fly
response to cytokine GO:0034097 232 0.016
nucleoside catabolic process GO:0009164 408 0.016
lipid biosynthetic process GO:0008610 177 0.016
Yeast
histone exchange GO:0043486 3 0.016
ribonucleoside catabolic process GO:0042454 406 0.016
peptidyl serine modification GO:0018209 106 0.016
positive regulation of ras gtpase activity GO:0032320 117 0.016
Yeast
protein acetylation GO:0006473 116 0.016
tube morphogenesis GO:0035239 95 0.016
neuron differentiation GO:0030182 138 0.016
cell fate determination GO:0001709 3 0.016
cell fate commitment GO:0045165 27 0.015
response to hypoxia GO:0001666 96 0.015
cellular ketone metabolic process GO:0042180 80 0.015
multicellular organism reproduction GO:0032504 42 0.015
Fly
positive regulation of endopeptidase activity GO:0010950 84 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
methylation GO:0032259 106 0.015
eye development GO:0001654 42 0.015
cellular response to organonitrogen compound GO:0071417 124 0.015
regulation of oocyte development GO:0060281 1 0.015
cell development GO:0048468 328 0.015
Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
protein dna complex subunit organization GO:0071824 80 0.014
photoreceptor cell differentiation GO:0046530 2 0.014
adult locomotory behavior GO:0008344 1 0.014
cell projection morphogenesis GO:0048858 129 0.014
cellular macromolecule catabolic process GO:0044265 380 0.014
regulation of gtp catabolic process GO:0033124 180 0.013
Yeast
negative regulation of protein modification process GO:0031400 200 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
ncrna metabolic process GO:0034660 108 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
muscle cell differentiation GO:0042692 63 0.013
central nervous system development GO:0007417 123 0.013
rna splicing GO:0008380 131 0.013
regulation of body fluid levels GO:0050878 99 0.013
actin filament based process GO:0030029 224 0.013
Fly
compound eye development GO:0048749 1 0.013
mrna processing GO:0006397 133 0.012
microtubule polymerization or depolymerization GO:0031109 37 0.012
generation of neurons GO:0048699 152 0.012
striated muscle cell differentiation GO:0051146 43 0.012
regulation of mapk cascade GO:0043408 262 0.012
spindle assembly involved in mitosis GO:0090307 12 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.012
positive regulation of developmental process GO:0051094 314 0.012
regulation of protein kinase activity GO:0045859 289 0.012
regulation of cell differentiation GO:0045595 393 0.012
regulation of proteolysis GO:0030162 293 0.012
single organismal cell cell adhesion GO:0016337 148 0.012
ribosome biogenesis GO:0042254 48 0.011
negative regulation of catalytic activity GO:0043086 335 0.011
regulation of nuclear division GO:0051783 65 0.011
regulation of gtpase activity GO:0043087 180 0.011
Yeast
innate immune response GO:0045087 178 0.011
cation transmembrane transport GO:0098655 238 0.011
regulation of mrna metabolic process GO:1903311 53 0.011
negative regulation of transferase activity GO:0051348 124 0.011
regulation of developmental growth GO:0048638 30 0.011
regulation of chromatin organization GO:1902275 56 0.011
positive regulation of mrna metabolic process GO:1903313 19 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
atp dependent chromatin remodeling GO:0043044 25 0.011
protein stabilization GO:0050821 64 0.011
purine containing compound catabolic process GO:0072523 411 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.011
regulation of cellular component movement GO:0051270 334 0.011
cell projection organization GO:0030030 252 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
Yeast
protein maturation GO:0051604 233 0.010
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.010
neuroblast proliferation GO:0007405 4 0.010
guanosine containing compound metabolic process GO:1901068 244 0.010
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.010
multi organism reproductive process GO:0044703 54 0.010
Fly
response to lipopolysaccharide GO:0032496 70 0.010
positive regulation of organelle organization GO:0010638 195 0.010
protein localization to cell surface GO:0034394 28 0.010
lymphocyte activation GO:0046649 133 0.010
rna splicing via transesterification reactions GO:0000375 90 0.010

KPNB1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012
cancer DOID:162 167 0.012
central nervous system disease DOID:331 186 0.012
nervous system disease DOID:863 431 0.012