|
|
golgi to plasma membrane cftr protein transport
|
GO:0043000 |
1 |
1.000
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.989
|
Human |
|
|
intermediate filament bundle assembly
|
GO:0045110 |
5 |
0.987
|
|
|
|
intermediate filament based process
|
GO:0045103 |
17 |
0.984
|
Human |
|
|
hair cycle
|
GO:0042633 |
28 |
0.982
|
Human |
|
|
intermediate filament organization
|
GO:0045109 |
10 |
0.982
|
Human |
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
17 |
0.960
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.886
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.881
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.846
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.832
|
Human |
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.808
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.782
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.741
|
Human |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.732
|
Human |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.724
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.664
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.629
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.627
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.620
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.599
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.597
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.585
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.580
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.529
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.528
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.522
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.515
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.513
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.508
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.500
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.489
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.484
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.484
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.479
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.455
|
Human |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.453
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.438
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.421
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.418
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.414
|
Human |
|
|
desmosome assembly
|
GO:0002159 |
4 |
0.408
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.395
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.385
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.383
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.377
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.376
|
Zebrafish |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.371
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.365
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.364
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.363
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.363
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.356
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.353
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.349
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.341
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.334
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.333
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.330
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.327
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.325
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.321
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.320
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.318
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.307
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.297
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.293
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.293
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.293
|
|
|
|
post golgi vesicle mediated transport
|
GO:0006892 |
36 |
0.289
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.287
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.287
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.285
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.283
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.280
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.278
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.278
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.275
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
33 |
0.272
|
|
|
|
system process
|
GO:0003008 |
349 |
0.267
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.260
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.255
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.253
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.253
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.247
|
Human |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.247
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.244
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.241
|
Human |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.241
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.241
|
|
|
|
striated muscle cell development
|
GO:0055002 |
27 |
0.239
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.232
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.231
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.228
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.227
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.224
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.214
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.214
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.213
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.212
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.212
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.207
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.205
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.205
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.203
|
Human |
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.203
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.202
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.199
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.199
|
|
|
|
cardiac muscle cell action potential involved in contraction
|
GO:0086002 |
21 |
0.196
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.195
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.194
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.193
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.187
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.185
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.185
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.183
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.183
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.181
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.180
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.178
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.176
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.175
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.171
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.167
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.165
|
Human |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.163
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.162
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.162
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.158
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.157
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.156
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.154
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.154
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.151
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.149
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.143
|
Human |
|
|
cell activation
|
GO:0001775 |
213 |
0.142
|
Human |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.141
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.138
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.137
|
Zebrafish |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.136
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.134
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
37 |
0.131
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.131
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.130
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.130
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.130
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.127
|
Human |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.126
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.126
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.122
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.122
|
|
|
|
molting cycle
|
GO:0042303 |
28 |
0.122
|
Human |
|
|
cardiac conduction
|
GO:0061337 |
23 |
0.121
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.119
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.118
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.117
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.117
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.117
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.116
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.115
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.114
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.113
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.108
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.106
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.106
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.105
|
|
|
|
golgi to plasma membrane transport
|
GO:0006893 |
21 |
0.102
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.101
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.100
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.100
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.099
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.098
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.098
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.097
|
|
|
|
regulation of heart rate
|
GO:0002027 |
38 |
0.096
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.095
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.095
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.095
|
|
|
|
regulation of heart rate by cardiac conduction
|
GO:0086091 |
19 |
0.094
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.093
|
|
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
20 |
0.091
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.091
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.090
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.090
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.089
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.089
|
|
|
|
neutrophil degranulation
|
GO:0043312 |
3 |
0.089
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.088
|
|
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.088
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.088
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.087
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.086
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.086
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.086
|
|
|
|
neutrophil mediated immunity
|
GO:0002446 |
4 |
0.086
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.086
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.085
|
|
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.085
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.085
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.085
|
|
|
|
sarcomere organization
|
GO:0045214 |
8 |
0.084
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.084
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.083
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.082
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.080
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.079
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.078
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.078
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.078
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.078
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.077
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.076
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.075
|
Human |
|
|
action potential
|
GO:0001508 |
34 |
0.074
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.074
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.073
|
|
|
|
negative regulation of axon extension
|
GO:0030517 |
2 |
0.073
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.073
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.073
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.073
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.070
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.070
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.069
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.069
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.069
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.068
|
Zebrafish |
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.067
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.067
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.067
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.065
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.065
|
|
|
|
ventricular cardiac muscle tissue development
|
GO:0003229 |
14 |
0.064
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.063
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.062
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.062
|
|
|
|
amino acid activation
|
GO:0043038 |
12 |
0.061
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.061
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.060
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.059
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.059
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.058
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.058
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.058
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.057
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.056
|
|
|
|
lung saccule development
|
GO:0060430 |
2 |
0.056
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.056
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.056
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.056
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.055
|
|
|
|
golgi to plasma membrane protein transport
|
GO:0043001 |
19 |
0.055
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.055
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.055
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.054
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.054
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.054
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.054
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.054
|
|
|
|
negative regulation of catagen
|
GO:0051796 |
1 |
0.053
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.053
|
Human |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.053
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.053
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.052
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.052
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.052
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
27 |
0.052
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.051
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.051
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.051
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.051
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
23 |
0.050
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.050
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.049
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.049
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.049
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.049
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.049
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.049
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.048
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.048
|
|
|
|
positive regulation of cytokinesis
|
GO:0032467 |
29 |
0.048
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.048
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.047
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.047
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.047
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.047
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.047
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.047
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.046
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
14 |
0.046
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.046
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.046
|
|
|
|
inorganic anion transmembrane transport
|
GO:0098661 |
47 |
0.045
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.044
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.044
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.044
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.044
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.044
|
|
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.043
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.043
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.043
|
|
|
|
respiratory system development
|
GO:0060541 |
22 |
0.043
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.042
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.042
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.042
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.041
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.041
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.041
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.041
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.041
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.041
|
|
|
|
growth
|
GO:0040007 |
202 |
0.041
|
Zebrafish |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.041
|
|
|
|
epithelial cell fate commitment
|
GO:0072148 |
3 |
0.040
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.040
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.039
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.039
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.039
|
|
|
|
catagen
|
GO:0042637 |
3 |
0.038
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.038
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
19 |
0.038
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.038
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.038
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.038
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.037
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.037
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.037
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.037
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.037
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.037
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.036
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.036
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.036
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.036
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.035
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.035
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.035
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.035
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.035
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.034
|
|
|
|
regulation of cardiac muscle cell contraction
|
GO:0086004 |
23 |
0.034
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.034
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.034
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.034
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.034
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.033
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.033
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.033
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.033
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.033
|
|
|
|
lens fiber cell differentiation
|
GO:0070306 |
2 |
0.033
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.033
|
|
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.033
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.033
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.033
|
Human |
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.033
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.032
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.032
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.032
|
|
|
|
negative regulation of glial cell differentiation
|
GO:0045686 |
1 |
0.032
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.032
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.032
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.032
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.032
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.031
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.031
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.031
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.031
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.030
|
|
|
|
regulation of metalloenzyme activity
|
GO:0048552 |
3 |
0.030
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.030
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.030
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.030
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.030
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.029
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.029
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.029
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.029
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.029
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.029
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.029
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.029
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
7 |
0.029
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.029
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.029
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.029
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.029
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.029
|
|
|
|
myofibril assembly
|
GO:0030239 |
10 |
0.028
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.028
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.028
|
|
|
|
cochlea development
|
GO:0090102 |
1 |
0.028
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.028
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.028
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.027
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.027
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.027
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.027
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.027
|
|
|
|
regulation of astrocyte differentiation
|
GO:0048710 |
3 |
0.027
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.027
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.026
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.026
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
20 |
0.026
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.026
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.026
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
13 |
0.026
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.025
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.025
|
|
|
|
cardiac muscle cell cardiac muscle cell adhesion
|
GO:0086042 |
1 |
0.025
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.025
|
|
|
|
cardiac muscle cell action potential
|
GO:0086001 |
23 |
0.025
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.025
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.025
|
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
4 |
0.025
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.025
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.025
|
|
|
|
muscle organ morphogenesis
|
GO:0048644 |
19 |
0.025
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.025
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.024
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.024
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.024
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
18 |
0.024
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.024
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.024
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.024
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.023
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.023
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.023
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.023
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.023
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.023
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.023
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.023
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.023
|
|
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
4 |
0.023
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.023
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.022
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.022
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.022
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.022
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.022
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.022
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.022
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
25 |
0.022
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.022
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.022
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
37 |
0.021
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.021
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.021
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.021
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.021
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.021
|
|
|
|
phagocytosis
|
GO:0006909 |
42 |
0.021
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.021
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.021
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.021
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.021
|
Zebrafish |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.021
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.021
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.021
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.021
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.021
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.021
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.021
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.021
|
|
|
|
memory
|
GO:0007613 |
3 |
0.020
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.020
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.020
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.020
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.020
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.020
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.020
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.020
|
|