|
|
biological adhesion
|
GO:0022610 |
331 |
0.797
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.532
|
Worm |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.518
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.465
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.338
|
Fly |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.317
|
Zebrafish Mouse Fly |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.290
|
|
|
|
system process
|
GO:0003008 |
349 |
0.280
|
Fly |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.279
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.251
|
Worm |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.248
|
Worm Fly |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.222
|
Zebrafish Mouse Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.219
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.218
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.216
|
Human |
|
|
head development
|
GO:0060322 |
108 |
0.215
|
Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.215
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.210
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.201
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.197
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.191
|
Zebrafish |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.186
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.185
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.176
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.176
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.164
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.161
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.160
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.160
|
Worm Fly |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.158
|
Human |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.151
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.147
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.143
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.141
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.131
|
Worm Fly |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.131
|
Zebrafish Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.131
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.130
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.130
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.128
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.128
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.126
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.126
|
Human |
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.126
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.125
|
Fly |
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.124
|
Worm |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.124
|
Human Fly |
|
|
tissue migration
|
GO:0090130 |
119 |
0.121
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.115
|
Worm |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.115
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.114
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.113
|
Worm |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.110
|
|
|
|
growth
|
GO:0040007 |
202 |
0.110
|
Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.108
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.106
|
Human Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.104
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.104
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.100
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.100
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.099
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.099
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.096
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.094
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.091
|
Zebrafish Mouse |
|
|
telencephalon development
|
GO:0021537 |
17 |
0.091
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.090
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.090
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.089
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.087
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.086
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.083
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.082
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.082
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.082
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.080
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.080
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.080
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.079
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.079
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.078
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.077
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.077
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.076
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.076
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.075
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.075
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.075
|
|
|
|
luteolysis
|
GO:0001554 |
3 |
0.073
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.072
|
Fly |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.071
|
Fly |
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.070
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.069
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.067
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.067
|
Human Worm Fly |
|
|
response to radiation
|
GO:0009314 |
151 |
0.067
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.065
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.064
|
Human |
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.064
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.063
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.062
|
Worm |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.062
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.061
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.060
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.059
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.058
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.058
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.057
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.056
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.056
|
Fly |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.055
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.055
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.055
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.054
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.054
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.054
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.053
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.053
|
Human |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.053
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.052
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.052
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.052
|
|
|
|
positive regulation of keratinocyte migration
|
GO:0051549 |
4 |
0.051
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.050
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.049
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.049
|
Human |
|
|
hippocampus development
|
GO:0021766 |
1 |
0.049
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.048
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.048
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.048
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.048
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.047
|
Worm |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.047
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.046
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.046
|
Human Fly |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.046
|
|
|
|
cerebral cortex development
|
GO:0021987 |
10 |
0.046
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.045
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.045
|
Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.045
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.045
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.045
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.045
|
Worm |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.044
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.044
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.043
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.041
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.041
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.041
|
Fly |
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.041
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.040
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.040
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.039
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.039
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.039
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.039
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.038
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.038
|
Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.038
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.038
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.038
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.038
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.037
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.037
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.036
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.036
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.036
|
Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.036
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.036
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.036
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.035
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.035
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.035
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.035
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.035
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.035
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.035
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.035
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.035
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.035
|
Human |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.034
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.034
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.034
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.034
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.034
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.034
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.033
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.033
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.033
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.033
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.033
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.033
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.032
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.032
|
Fly |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.032
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.032
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.031
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.031
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.031
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.031
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.031
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.031
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.031
|
Worm Fly |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.031
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.030
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.030
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.030
|
Worm |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.030
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.030
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.030
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.030
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.030
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.030
|
|
|
|
negative regulation of neutrophil chemotaxis
|
GO:0090024 |
2 |
0.030
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.030
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.030
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.030
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.030
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.030
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.029
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.029
|
Fly |
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.029
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.029
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.029
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.029
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.029
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.029
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.028
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.028
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.028
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.028
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.028
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.027
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.027
|
Worm Fly |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.027
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.027
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.027
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.027
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.027
|
Fly |
|
|
neuron development
|
GO:0048666 |
113 |
0.027
|
Worm Fly |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.027
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.027
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.027
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.027
|
Fly |
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.026
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.026
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.026
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.026
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.026
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.026
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.026
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.025
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.025
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.025
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.025
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.025
|
Fly |
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.025
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.025
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.025
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.025
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.025
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.025
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.025
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.025
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.025
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.024
|
Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.024
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.024
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.024
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.024
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.024
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.024
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.024
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.024
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.024
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.024
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.023
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.023
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.023
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.023
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.023
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.023
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.023
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.023
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.023
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.023
|
|
|
|
regulation of keratinocyte migration
|
GO:0051547 |
4 |
0.023
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.023
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.023
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.023
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.022
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.022
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.022
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.022
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.022
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.022
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.022
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.022
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.022
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.022
|
|
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.022
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.022
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.022
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.021
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.021
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.021
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.021
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.021
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.021
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.021
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.021
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.021
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.021
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.021
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.021
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.021
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.021
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.021
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.020
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.020
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.020
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.020
|
Fly |
|
|
protein maturation
|
GO:0051604 |
233 |
0.020
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.020
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
3 |
0.020
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.020
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.020
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.020
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.020
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.020
|
Fly |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.020
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.020
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.020
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.020
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.020
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.019
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.019
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.019
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.019
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.019
|
|
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.019
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.019
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.019
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.019
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.019
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.019
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.019
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.019
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.019
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.019
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.019
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.019
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.019
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.019
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.019
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.019
|
Fly |
|
|
compound eye development
|
GO:0048749 |
1 |
0.019
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.019
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.019
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.019
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.019
|
Worm Fly |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.018
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.018
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.018
|
Fly |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.018
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.018
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.018
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.018
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.018
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.018
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.018
|
|
|
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.018
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.018
|
|
|
|
negative regulation of axon guidance
|
GO:1902668 |
1 |
0.018
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.018
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.018
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.018
|
|
|
|
elastic fiber assembly
|
GO:0048251 |
3 |
0.018
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.018
|
Worm Fly |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.018
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.018
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.018
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.018
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.018
|
Zebrafish |
|
|
endochondral bone growth
|
GO:0003416 |
1 |
0.018
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.017
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.017
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.017
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.017
|
|
|
|
soft palate development
|
GO:0060023 |
3 |
0.017
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.017
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.017
|
|
|
|
retina vasculature morphogenesis in camera type eye
|
GO:0061299 |
3 |
0.017
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.017
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.017
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.017
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.017
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.017
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.017
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.017
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.017
|
Worm |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.017
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.017
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.017
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.017
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.017
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.017
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.017
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.016
|
|
|
|
negative regulation of gastrulation
|
GO:2000542 |
4 |
0.016
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.016
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.016
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.016
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.016
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.016
|
|
|
|
multicellular organismal macromolecule metabolic process
|
GO:0044259 |
29 |
0.016
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.016
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.016
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.016
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.016
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.016
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.016
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.016
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.016
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.016
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.016
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.016
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.016
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.016
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.016
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.016
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.016
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.016
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.016
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.016
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.016
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.016
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.015
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.015
|
Worm Fly |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.015
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.015
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.015
|
|
|
|
collagen metabolic process
|
GO:0032963 |
28 |
0.015
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.015
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
29 |
0.015
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.015
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.015
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.015
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.015
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.015
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.015
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.015
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.015
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.015
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.015
|
Worm |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.015
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.015
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.015
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.015
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.015
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.015
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.015
|
|
|
|
positive regulation of vasoconstriction
|
GO:0045907 |
3 |
0.015
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.015
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.015
|
Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.015
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.015
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.015
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.015
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.015
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
10 |
0.015
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.015
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.014
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.014
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.014
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.014
|
Human |
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.014
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.014
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.014
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.014
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.014
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.014
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.014
|
|
|
|
negative regulation of axon extension
|
GO:0030517 |
2 |
0.014
|
|
