Homo sapiens

0 known processes

LARS

leucyl-tRNA synthetase

(Aliases: PIG44,LEURS,FLJ10595,hr025Cl,LRS,LEUS,KIAA1352,LARS1,FLJ21788,HSPC192,RNTLS)

LARS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amino acid activation GO:0043038 12 0.833
Yeast
trna aminoacylation for protein translation GO:0006418 8 0.726
Yeast
trna aminoacylation GO:0043039 12 0.685
Yeast
cellular amino acid metabolic process GO:0006520 116 0.410
Yeast
trna metabolic process GO:0006399 35 0.215
Yeast
translation GO:0006412 132 0.150
Yeast
regulation of translation GO:0006417 89 0.133
purine ribonucleoside catabolic process GO:0046130 398 0.122
ncrna metabolic process GO:0034660 108 0.118
Yeast
post embryonic development GO:0009791 2 0.116
Worm
transcription from rna polymerase iii promoter GO:0006383 19 0.088
negative regulation of protein metabolic process GO:0051248 391 0.078
purine nucleoside triphosphate catabolic process GO:0009146 392 0.075
posttranscriptional regulation of gene expression GO:0010608 213 0.070
regulation of tor signaling GO:0032006 30 0.060
Yeast
purine ribonucleoside metabolic process GO:0046128 437 0.044
organophosphate catabolic process GO:0046434 430 0.043
rna processing GO:0006396 255 0.043
negative regulation of cell size GO:0045792 3 0.041
trna processing GO:0008033 23 0.040
ncrna processing GO:0034470 83 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.039
ribonucleoside triphosphate catabolic process GO:0009203 391 0.037
protein localization to organelle GO:0033365 280 0.036
positive regulation of cellular catabolic process GO:0031331 284 0.035
oxidation reduction process GO:0055114 396 0.034
ribonucleoside triphosphate metabolic process GO:0009199 412 0.032
purine nucleoside triphosphate metabolic process GO:0009144 412 0.032
purine containing compound catabolic process GO:0072523 411 0.032
positive regulation of transcription from rna polymerase iii promoter GO:0045945 10 0.032
nucleoside triphosphate catabolic process GO:0009143 394 0.032
guanosine containing compound catabolic process GO:1901069 239 0.031
immune response GO:0006955 307 0.030
purine nucleoside catabolic process GO:0006152 398 0.029
mitotic cell cycle process GO:1903047 286 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
purine ribonucleotide catabolic process GO:0009154 404 0.027
regulation of protein localization GO:0032880 296 0.026
amine metabolic process GO:0009308 44 0.026
glycosyl compound catabolic process GO:1901658 413 0.025
oogenesis GO:0048477 2 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
response to oxygen containing compound GO:1901700 369 0.025
positive regulation of transport GO:0051050 336 0.025
determination of adult lifespan GO:0008340 2 0.025
vesicle mediated transport GO:0016192 371 0.024
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
leukocyte migration GO:0050900 107 0.024
positive regulation of cellular component organization GO:0051130 376 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
system process GO:0003008 349 0.024
nucleotide catabolic process GO:0009166 408 0.024
ribonucleoside catabolic process GO:0042454 406 0.023
positive regulation of phosphorylation GO:0042327 394 0.022
regeneration GO:0031099 4 0.022
cellular response to cytokine stimulus GO:0071345 181 0.022
cellular response to nitrogen compound GO:1901699 144 0.022
female gamete generation GO:0007292 2 0.021
cell morphogenesis GO:0000902 296 0.021
cellular response to external stimulus GO:0071496 111 0.021
nucleoside catabolic process GO:0009164 408 0.020
cell growth GO:0016049 160 0.020
positive regulation of catabolic process GO:0009896 310 0.020
defense response GO:0006952 315 0.019
protein folding GO:0006457 38 0.018
regulation of establishment of protein localization GO:0070201 242 0.018
neuromuscular junction development GO:0007528 3 0.018
cellular protein catabolic process GO:0044257 261 0.018
carbohydrate metabolic process GO:0005975 207 0.018
response to acid chemical GO:0001101 66 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
actin filament based process GO:0030029 224 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
rna interference GO:0016246 4 0.018
endocytosis GO:0006897 159 0.018
negative regulation of transferase activity GO:0051348 124 0.018
regulation of epithelial cell proliferation GO:0050678 113 0.018
regulation of transcription from rna polymerase iii promoter GO:0006359 13 0.017
response to cytokine GO:0034097 232 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
regulation of cell growth GO:0001558 135 0.017
growth GO:0040007 202 0.017
regulation of anatomical structure size GO:0090066 101 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
single organism cellular localization GO:1902580 332 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.016
response to extracellular stimulus GO:0009991 85 0.016
negative regulation of cell death GO:0060548 345 0.016
regulation of transferase activity GO:0051338 355 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
cell part morphogenesis GO:0032990 137 0.016
negative regulation of catalytic activity GO:0043086 335 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
actin cytoskeleton organization GO:0030036 207 0.016
maintenance of location GO:0051235 112 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
cellular amine metabolic process GO:0044106 41 0.015
cellular response to organonitrogen compound GO:0071417 124 0.015
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
nitrogen compound transport GO:0071705 191 0.015
oocyte development GO:0048599 1 0.015
dephosphorylation GO:0016311 209 0.015
translational initiation GO:0006413 48 0.015
innate immune response GO:0045087 178 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
positive regulation of cell size GO:0045793 3 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
membrane lipid metabolic process GO:0006643 53 0.015
protein ubiquitination GO:0016567 314 0.015
rna modification GO:0009451 27 0.015
positive regulation of kinase activity GO:0033674 204 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.014
protein localization to nucleus GO:0034504 136 0.014
organelle fission GO:0048285 149 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
cellular component morphogenesis GO:0032989 314 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
dna repair GO:0006281 198 0.014
rho protein signal transduction GO:0007266 26 0.014
cytoplasmic translational initiation GO:0002183 6 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
sphingolipid metabolic process GO:0006665 38 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
response to organonitrogen compound GO:0010243 156 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.013
positive regulation of rho protein signal transduction GO:0035025 4 0.013
cellular response to starvation GO:0009267 58 0.013
generation of precursor metabolites and energy GO:0006091 68 0.013
methylation GO:0032259 106 0.013
modification dependent macromolecule catabolic process GO:0043632 212 0.013
regulation of protein transport GO:0051223 213 0.013
negative regulation of phosphatase activity GO:0010923 61 0.013
response to nitrogen compound GO:1901698 184 0.013
negative regulation of synaptic transmission GO:0050805 2 0.013
intracellular protein transport GO:0006886 270 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.013
positive regulation of tor signaling GO:0032008 11 0.013
ribonucleoprotein complex subunit organization GO:0071826 81 0.012
neurological system process GO:0050877 163 0.012
regulation of cellular amine metabolic process GO:0033238 11 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
response to hormone GO:0009725 175 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
mrna metabolic process GO:0016071 175 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
actin filament organization GO:0007015 128 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
positive regulation of hydrolase activity GO:0051345 331 0.012
memory GO:0007613 3 0.012
small gtpase mediated signal transduction GO:0007264 78 0.012
locomotory behavior GO:0007626 1 0.012
macromolecule methylation GO:0043414 97 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
compound eye development GO:0048749 1 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
nervous system development GO:0007399 293 0.012
regulation of cell morphogenesis GO:0022604 153 0.011
regulation of binding GO:0051098 111 0.011
regulation of cellular component size GO:0032535 82 0.011
protein catabolic process GO:0030163 325 0.011
response to interferon gamma GO:0034341 39 0.011
response to nutrient levels GO:0031667 81 0.011
establishment of rna localization GO:0051236 39 0.011
cellular response to acid chemical GO:0071229 44 0.011
cytoplasmic transport GO:0016482 379 0.011
positive regulation of protein complex assembly GO:0031334 86 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
organelle assembly GO:0070925 176 0.011
regulation of cell differentiation GO:0045595 393 0.011
cation transmembrane transport GO:0098655 238 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
mitochondrion organization GO:0007005 156 0.011
protein maturation GO:0051604 233 0.011
microtubule based process GO:0007017 210 0.011
regulation of intracellular transport GO:0032386 195 0.011
endothelial cell proliferation GO:0001935 65 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
regulation of protein kinase activity GO:0045859 289 0.011
nuclear transport GO:0051169 179 0.010
ossification GO:0001503 121 0.010
lymphocyte homeostasis GO:0002260 4 0.010
negative regulation of catabolic process GO:0009895 104 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
regulation of apoptotic signaling pathway GO:2001233 175 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
protein targeting GO:0006605 187 0.010
cellular amide metabolic process GO:0043603 69 0.010
ion homeostasis GO:0050801 230 0.010
cellular response to interferon gamma GO:0071346 24 0.010
positive regulation of nucleoside metabolic process GO:0045979 186 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
cell projection organization GO:0030030 252 0.010
ribonucleoprotein complex assembly GO:0022618 78 0.010
regulation of intracellular protein transport GO:0033157 123 0.010
cell type specific apoptotic process GO:0097285 125 0.010
tripartite regional subdivision GO:0007351 2 0.010

LARS disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.017
immune system disease DOID:2914 155 0.014
myopathy DOID:423 104 0.012
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012
sensory system disease DOID:0050155 203 0.010
eye and adnexa disease DOID:1492 150 0.010
nervous system disease DOID:863 431 0.010
eye disease DOID:5614 149 0.010
central nervous system disease DOID:331 186 0.010
neurodegenerative disease DOID:1289 102 0.010