|
|
hippo signaling
|
GO:0035329 |
20 |
1.000
|
|
|
|
negative regulation of hippo signaling
|
GO:0035331 |
6 |
1.000
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.998
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.995
|
Human |
|
|
digestive system development
|
GO:0055123 |
75 |
0.990
|
Worm |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.983
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.981
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.979
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.975
|
Fly |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.969
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.960
|
Mouse |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.957
|
Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.956
|
Fly |
|
|
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules
|
GO:0016339 |
2 |
0.955
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.951
|
Fly |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.938
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.938
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.931
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.930
|
Human |
|
|
digestive tract development
|
GO:0048565 |
75 |
0.929
|
Worm |
|
|
cytoplasmic sequestering of protein
|
GO:0051220 |
12 |
0.926
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.923
|
|
|
|
system process
|
GO:0003008 |
349 |
0.922
|
Worm |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.901
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.893
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.893
|
Fly |
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.892
|
|
|
|
notch signaling involved in heart development
|
GO:0061314 |
2 |
0.880
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.877
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.874
|
|
|
|
cartilage morphogenesis
|
GO:0060536 |
1 |
0.870
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.870
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.865
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.864
|
Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.863
|
Mouse Fly |
|
|
stem cell division
|
GO:0017145 |
2 |
0.863
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.862
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.856
|
Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.852
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.851
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.846
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.844
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.843
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.840
|
Fly |
|
|
fat soluble vitamin metabolic process
|
GO:0006775 |
19 |
0.840
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.838
|
Fly |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.815
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.814
|
|
|
|
regulation of organ growth
|
GO:0046620 |
7 |
0.811
|
Mouse |
|
|
negative regulation of vitamin d biosynthetic process
|
GO:0010957 |
5 |
0.807
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.795
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.790
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.786
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.786
|
Human |
|
|
vitamin d receptor signaling pathway
|
GO:0070561 |
4 |
0.785
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.779
|
Fly |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.772
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.769
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.768
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.764
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.759
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.753
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.747
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.747
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.742
|
Fly |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.742
|
Human |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.739
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.738
|
Human |
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.737
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.735
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.731
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.722
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.722
|
Human |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.720
|
Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.717
|
Fly |
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.717
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.717
|
|
|
|
hair cycle
|
GO:0042633 |
28 |
0.714
|
|
|
|
growth
|
GO:0040007 |
202 |
0.710
|
Mouse Fly |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.704
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.700
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
34 |
0.695
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.695
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.693
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.693
|
Fly |
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.687
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.686
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.675
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.673
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.669
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.666
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.663
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.659
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.655
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.652
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.649
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.649
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.646
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.637
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.633
|
|
|
|
integrin activation
|
GO:0033622 |
8 |
0.629
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.624
|
Worm |
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.622
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.622
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.622
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.618
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.616
|
|
|
|
regulation of keratinocyte proliferation
|
GO:0010837 |
11 |
0.616
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.611
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.611
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.607
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.603
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.600
|
|
|
|
gene silencing by mirna
|
GO:0035195 |
23 |
0.595
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.587
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.587
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.585
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.582
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.579
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.579
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.574
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.571
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.569
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.565
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.560
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.560
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.543
|
Fly |
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.543
|
Fly |
|
|
protein localization to centrosome
|
GO:0071539 |
5 |
0.537
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.537
|
Human |
|
|
left right pattern formation
|
GO:0060972 |
2 |
0.535
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.533
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.533
|
Human |
|
|
vitamin d metabolic process
|
GO:0042359 |
10 |
0.531
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.510
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.503
|
Fly |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.503
|
Fly |
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.501
|
|
|
|
positive regulation of blood vessel endothelial cell migration
|
GO:0043536 |
16 |
0.500
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.499
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.496
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.491
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.491
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.483
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.479
|
Fly |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.476
|
|
|
|
keratinocyte proliferation
|
GO:0043616 |
17 |
0.473
|
|
|
|
organ growth
|
GO:0035265 |
12 |
0.466
|
Mouse Fly |
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.463
|
|
|
|
vitamin metabolic process
|
GO:0006766 |
26 |
0.456
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.454
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.452
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.452
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.443
|
Mouse Fly |
|
|
protein localization to cytoskeleton
|
GO:0044380 |
11 |
0.442
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.440
|
Fly |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.438
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.438
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.433
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.433
|
Fly |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.430
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.422
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.421
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.410
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.408
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.408
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.407
|
Human |
|
|
cytoplasmic mrna processing body assembly
|
GO:0033962 |
10 |
0.407
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.404
|
Human |
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.398
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.397
|
Fly |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.397
|
Human |
|
|
positive regulation of organ growth
|
GO:0046622 |
2 |
0.397
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.395
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.391
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.390
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.388
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.386
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.386
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.384
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.384
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.381
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.381
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.377
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.377
|
Fly |
|
|
negative regulation of catenin import into nucleus
|
GO:0035414 |
7 |
0.373
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.372
|
|
|
|
molting cycle process
|
GO:0022404 |
12 |
0.371
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.370
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.369
|
Human |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.367
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.366
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.366
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.361
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.354
|
Fly |
|
|
cell junction organization
|
GO:0034330 |
79 |
0.352
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.351
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.350
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.349
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.348
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.347
|
|
|
|
negative regulation of cell cell adhesion by negative regulation of transcription from rna polymerase ii promoter
|
GO:1900387 |
1 |
0.344
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.344
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.343
|
Fly |
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.342
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.342
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.341
|
|
|
|
cell cell adhesion via plasma membrane adhesion molecules
|
GO:0098742 |
19 |
0.341
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.337
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.336
|
Fly |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.333
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.329
|
Mouse |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.329
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.326
|
Fly |
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.326
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.325
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.324
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.316
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.315
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.313
|
Fly |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.312
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.307
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.304
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.303
|
Mouse |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.300
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.298
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.296
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.293
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.292
|
Fly |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.289
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.288
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.288
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.286
|
|
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.284
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.283
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.282
|
|
|
|
protein localization to microtubule cytoskeleton
|
GO:0072698 |
10 |
0.282
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.280
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.280
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.276
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.273
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.272
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.272
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.270
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.270
|
Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.269
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.263
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.262
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.262
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.261
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.260
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.259
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.257
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.255
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.253
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.248
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.246
|
Fly |
|
|
peptide transport
|
GO:0015833 |
74 |
0.246
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.246
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.243
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.240
|
Worm |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.239
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.239
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.238
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.237
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.236
|
Human |
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.231
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.225
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.225
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.225
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.222
|
Fly |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.221
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.218
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.217
|
Fly |
|
|
dendrite morphogenesis
|
GO:0048813 |
14 |
0.216
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.213
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.212
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.209
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.205
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.204
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.203
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.202
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.201
|
Fly |
|
|
regulation of steroid metabolic process
|
GO:0019218 |
32 |
0.200
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.200
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.200
|
|
|
|
negative regulation of vitamin metabolic process
|
GO:0046137 |
6 |
0.199
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.199
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.198
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.198
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.197
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.197
|
Human |
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.196
|
Human |
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.195
|
|
|
|
phospholipid biosynthetic process
|
GO:0008654 |
44 |
0.193
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.192
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.192
|
|
|
|
regulation of vitamin d receptor signaling pathway
|
GO:0070562 |
3 |
0.188
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.186
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.184
|
Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.184
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.182
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.180
|
Worm |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.180
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.179
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.178
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.178
|
|
|
|
desmosome organization
|
GO:0002934 |
5 |
0.176
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.175
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.174
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.174
|
Fly |
|
|
cell division
|
GO:0051301 |
168 |
0.174
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.173
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.172
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.171
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.167
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.166
|
|
|
|
regulation of gene silencing by rna
|
GO:0060966 |
6 |
0.165
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.165
|
|
|
|
negative regulation of cardiac muscle cell proliferation
|
GO:0060044 |
2 |
0.163
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.161
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.161
|
Worm |
|
|
vasculature development
|
GO:0001944 |
181 |
0.159
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.159
|
Fly |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.158
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.158
|
|
|
|
regulation of catenin import into nucleus
|
GO:0035412 |
18 |
0.157
|
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.155
|
|
|
|
regulation of vitamin metabolic process
|
GO:0030656 |
9 |
0.154
|
|
|
|
regulation of signal transduction by p53 class mediator
|
GO:1901796 |
26 |
0.154
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.153
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.153
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.153
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.153
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.150
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.149
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.149
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.149
|
Fly |
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.149
|
Human |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.148
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.148
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.147
|
Human |
|
|
response to lipid
|
GO:0033993 |
206 |
0.146
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.146
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.145
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.145
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.144
|
|
|
|
regulation of gene silencing
|
GO:0060968 |
24 |
0.144
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.143
|
Fly |
|
|
regulation of nf kappab import into nucleus
|
GO:0042345 |
22 |
0.143
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.142
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.141
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.140
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.140
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.140
|
Fly |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.139
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.139
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.139
|
|
|
|
hair follicle development
|
GO:0001942 |
11 |
0.139
|
|
|
|
nf kappab import into nucleus
|
GO:0042348 |
22 |
0.137
|
|
|
|
glycerophospholipid biosynthetic process
|
GO:0046474 |
40 |
0.137
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.137
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
3 |
0.137
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.135
|
Human |
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.134
|
|
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.133
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.132
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.131
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.131
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.129
|
|
|
|
cellular response to vitamin d
|
GO:0071305 |
5 |
0.129
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.126
|
|
|
|
regulation of alcohol biosynthetic process
|
GO:1902930 |
22 |
0.123
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.121
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.119
|
Human |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.119
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.119
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.119
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.119
|
Fly |
|
|
protein deacylation
|
GO:0035601 |
39 |
0.118
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.117
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.116
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.115
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.113
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.113
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.113
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.113
|
|
|
|
stem cell proliferation
|
GO:0072089 |
25 |
0.112
|
Fly |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.112
|
|
|
|
negative regulation of steroid metabolic process
|
GO:0045939 |
15 |
0.110
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.109
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
25 |
0.109
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.108
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.108
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.108
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.107
|
Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.107
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.107
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.107
|
|
|
|
regulation of hippo signaling
|
GO:0035330 |
8 |
0.107
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
41 |
0.105
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.105
|
|
|
|
cytoplasmic sequestering of nf kappab
|
GO:0007253 |
7 |
0.104
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
33 |
0.104
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.104
|
Human |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.102
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.102
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.102
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.101
|
|
|
|
hair cycle process
|
GO:0022405 |
12 |
0.101
|
|
|
|
negative regulation of keratinocyte proliferation
|
GO:0010839 |
5 |
0.100
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.100
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.100
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.099
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.099
|
Fly |
|
|
pigmentation
|
GO:0043473 |
22 |
0.098
|
|
|
|
lamellipodium assembly
|
GO:0030032 |
26 |
0.098
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.096
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.096
|
|
|
|
palate development
|
GO:0060021 |
13 |
0.096
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.095
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.094
|
Mouse |
|
|
response to vitamin d
|
GO:0033280 |
10 |
0.093
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.093
|
Fly |
|
|
positive regulation of nf kappab import into nucleus
|
GO:0042346 |
13 |
0.092
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.092
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.092
|
Human |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.091
|
|
|
|
skin morphogenesis
|
GO:0043589 |
6 |
0.091
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.091
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.091
|
Fly |
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.090
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
23 |
0.090
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.090
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.089
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.085
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.085
|
Fly |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.085
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.084
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.083
|
Fly |
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.081
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.081
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.081
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.081
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.080
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.079
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.079
|
|
|
|
epiboly involved in wound healing
|
GO:0090505 |
8 |
0.078
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.078
|
|
|
|
wound healing spreading of cells
|
GO:0044319 |
8 |
0.077
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.076
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.076
|
|
|
|
anoikis
|
GO:0043276 |
22 |
0.075
|
|
|
|
regulation of vitamin d biosynthetic process
|
GO:0060556 |
8 |
0.075
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.075
|
|
|
|
positive regulation of gene silencing by mirna
|
GO:2000637 |
3 |
0.075
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.074
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.073
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.073
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.073
|
|
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.073
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.071
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.071
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.070
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.070
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.069
|
Human |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.069
|
Worm |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.068
|
Mouse |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.068
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.067
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.067
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.067
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
25 |
0.067
|
|
|
|
cellular response to nutrient
|
GO:0031670 |
12 |
0.066
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.065
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.065
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.065
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.065
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.064
|
|
|
|
regulation of gene silencing by mirna
|
GO:0060964 |
6 |
0.064
|
|
|
|
negative regulation of lipid biosynthetic process
|
GO:0051055 |
22 |
0.064
|
|
|
|
epiboly
|
GO:0090504 |
9 |
0.063
|
|
|
|
mesoderm formation
|
GO:0001707 |
10 |
0.062
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.062
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.062
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.062
|
|
|
|
gene silencing by rna
|
GO:0031047 |
26 |
0.061
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.061
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.061
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.060
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.060
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.059
|
Human |
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.059
|
|
|
|
trachea development
|
GO:0060438 |
1 |
0.059
|
Fly |
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.058
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.057
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.057
|
|
|
|
negative regulation of response to extracellular stimulus
|
GO:0032105 |
5 |
0.057
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.057
|
|
|
|
fat soluble vitamin biosynthetic process
|
GO:0042362 |
11 |
0.056
|
|
