Homo sapiens

91 known processes

LCAT

lecithin-cholesterol acyltransferase

LCAT biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of triglyceride catabolic process GO:0010896 6 0.970
sterol esterification GO:0034434 10 0.926
neutral lipid catabolic process GO:0046461 12 0.925
very low density lipoprotein particle remodeling GO:0034372 10 0.924
protein lipid complex remodeling GO:0034368 16 0.907
high density lipoprotein particle remodeling GO:0034375 8 0.899
macromolecular complex remodeling GO:0034367 16 0.888
glycerolipid catabolic process GO:0046503 18 0.845
cell adhesion molecule production GO:0060352 3 0.719
triglyceride rich lipoprotein particle remodeling GO:0034370 10 0.711
cdc42 protein signal transduction GO:0032488 4 0.667
positive regulation of lipoprotein lipase activity GO:0051006 7 0.642
plasma lipoprotein particle organization GO:0071827 22 0.628
reverse cholesterol transport GO:0043691 8 0.566
negative regulation of sterol transport GO:0032372 8 0.529
postsynaptic membrane organization GO:0001941 2 0.512
plasma lipoprotein particle remodeling GO:0034369 16 0.502
regulation of lipid catabolic process GO:0050994 23 0.415
cholesterol import GO:0070508 4 0.389
neutral lipid metabolic process GO:0006638 27 0.384
negative regulation of cholesterol transport GO:0032375 8 0.369
regulation of lipoprotein lipase activity GO:0051004 12 0.355
sterol homeostasis GO:0055092 28 0.344
regulation of receptor catabolic process GO:2000644 2 0.323
presynaptic membrane organization GO:0097090 3 0.298
positive regulation of beta amyloid formation GO:1902004 4 0.292
amine metabolic process GO:0009308 44 0.274
cholesterol esterification GO:0034435 10 0.268
phospholipid efflux GO:0033700 11 0.265
cyclic nucleotide biosynthetic process GO:0009190 61 0.265
cyclic nucleotide metabolic process GO:0009187 82 0.259
acylglycerol metabolic process GO:0006639 27 0.258
phosphatidylcholine biosynthetic process GO:0006656 9 0.246
regulation of triglyceride metabolic process GO:0090207 11 0.242
sterol transport GO:0015918 39 0.232
lipid biosynthetic process GO:0008610 177 0.232
oxidation reduction process GO:0055114 396 0.230
rho protein signal transduction GO:0007266 26 0.228
cellular biogenic amine metabolic process GO:0006576 34 0.225
regulation of cholesterol metabolic process GO:0090181 4 0.221
cellular amine metabolic process GO:0044106 41 0.219
cyclic purine nucleotide metabolic process GO:0052652 60 0.217
plasma lipoprotein particle clearance GO:0034381 16 0.214
regulation of lipoprotein oxidation GO:0034442 3 0.212
glycerophospholipid metabolic process GO:0006650 84 0.211
cellular ketone metabolic process GO:0042180 80 0.203
cholesterol transport GO:0030301 39 0.201
cellular lipid metabolic process GO:0044255 303 0.200
lipid metabolic process GO:0006629 381 0.197
negative regulation of interleukin 1 secretion GO:0050711 4 0.197
negative regulation of cellular amide metabolic process GO:0034249 3 0.190
multicellular organismal lipid catabolic process GO:0044240 2 0.184
purine nucleotide biosynthetic process GO:0006164 84 0.184
small gtpase mediated signal transduction GO:0007264 78 0.181
regulation of defense response GO:0031347 154 0.181
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.178
positive regulation of rho protein signal transduction GO:0035025 4 0.176
receptor catabolic process GO:0032801 11 0.176
neurotransmitter gated ion channel clustering GO:0072578 1 0.175
positive regulation of nucleotide metabolic process GO:0045981 230 0.174
regulation of locomotion GO:0040012 329 0.173
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.169
carboxylic acid transport GO:0046942 63 0.166
dendritic spine maintenance GO:0097062 1 0.165
phosphatidylcholine metabolic process GO:0046470 19 0.164
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.161
triglyceride metabolic process GO:0006641 23 0.161
organophosphate ester transport GO:0015748 32 0.160
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.155
regulation of cellular ketone metabolic process GO:0010565 50 0.155
regulation of cytokine secretion GO:0050707 57 0.152
positive regulation of cgmp metabolic process GO:0030825 5 0.148
positive regulation of cgmp biosynthetic process GO:0030828 3 0.145
lipoprotein modification GO:0042160 4 0.142
organophosphate biosynthetic process GO:0090407 163 0.141
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.141
nucleotide biosynthetic process GO:0009165 109 0.131
lipoprotein metabolic process GO:0042157 42 0.130
Mouse Rat
regulation of interleukin 1 beta secretion GO:0050706 12 0.129
cellular response to oxygen radical GO:0071450 6 0.129
triglyceride catabolic process GO:0019433 10 0.129
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 1 0.128
regulation of rho protein signal transduction GO:0035023 79 0.127
positive regulation of cholesterol esterification GO:0010873 6 0.125
negative regulation of dendrite development GO:2000171 5 0.125
plasma lipoprotein particle assembly GO:0034377 9 0.125
Mouse
protein catabolic process GO:0030163 325 0.124
nucleoside phosphate biosynthetic process GO:1901293 109 0.123
cellular lipid catabolic process GO:0044242 65 0.123
steroid metabolic process GO:0008202 94 0.122
monocarboxylic acid metabolic process GO:0032787 185 0.122
positive regulation of catabolic process GO:0009896 310 0.121
regulation of cdc42 protein signal transduction GO:0032489 14 0.120
biological adhesion GO:0022610 331 0.118
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.117
positive regulation of dendritic spine development GO:0060999 2 0.117
ribose phosphate biosynthetic process GO:0046390 82 0.117
small molecule biosynthetic process GO:0044283 157 0.116
transmembrane transport GO:0055085 399 0.115
negative regulation of wound healing GO:0061045 25 0.113
ribonucleotide biosynthetic process GO:0009260 81 0.113
high density lipoprotein particle clearance GO:0034384 6 0.113
membrane organization GO:0061024 292 0.112
lipoprotein oxidation GO:0042161 4 0.111
regulation of blood coagulation GO:0030193 42 0.109
g protein coupled receptor signaling pathway GO:0007186 207 0.108
glycerolipid metabolic process GO:0046486 107 0.108
lipoprotein biosynthetic process GO:0042158 33 0.107
Mouse
ras protein signal transduction GO:0007265 73 0.107
regulation of immune response GO:0050776 201 0.106
cellular macromolecule catabolic process GO:0044265 380 0.106
purine containing compound biosynthetic process GO:0072522 88 0.106
negative regulation of cell migration GO:0030336 102 0.104
positive regulation of cellular component organization GO:0051130 376 0.104
regulation of lipoprotein metabolic process GO:0050746 7 0.103
mucosal immune response GO:0002385 21 0.103
very low density lipoprotein particle clearance GO:0034447 6 0.102
fatty acid metabolic process GO:0006631 115 0.102
positive regulation of amyloid precursor protein catabolic process GO:1902993 4 0.102
negative regulation of hydrolase activity GO:0051346 182 0.101
lipid catabolic process GO:0016042 84 0.101
anion transport GO:0006820 161 0.100
regeneration GO:0031099 4 0.099
positive regulation of hydrolase activity GO:0051345 331 0.099
regulation of cholesterol esterification GO:0010872 7 0.098
negative regulation of immune system process GO:0002683 136 0.097
single organism cellular localization GO:1902580 332 0.097
regulation of endothelial cell proliferation GO:0001936 56 0.097
organic anion transport GO:0015711 103 0.096
negative regulation of immune effector process GO:0002698 38 0.096
cytokine production GO:0001816 247 0.095
regulation of cell migration GO:0030334 289 0.094
ethanolamine containing compound metabolic process GO:0042439 26 0.093
phospholipid transport GO:0015914 23 0.093
chylomicron remnant clearance GO:0034382 4 0.093
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.092
cell cell adhesion involved in gastrulation GO:0070586 6 0.091
immune response GO:0006955 307 0.090
regulation of response to wounding GO:1903034 101 0.090
negative regulation of epithelial cell proliferation GO:0050680 48 0.090
regulation of endothelial cell migration GO:0010594 67 0.090
protein lipid complex subunit organization GO:0071825 24 0.088
defense response GO:0006952 315 0.087
high density lipoprotein particle assembly GO:0034380 5 0.087
Mouse
positive regulation of cellular catabolic process GO:0031331 284 0.087
regulation of protein transport GO:0051223 213 0.086
negative regulation of cell proliferation GO:0008285 228 0.086
negative regulation of amyloid precursor protein catabolic process GO:1902992 4 0.085
regulation of mapk cascade GO:0043408 262 0.083
regulation of establishment of protein localization GO:0070201 242 0.083
negative regulation of hemostasis GO:1900047 22 0.082
negative regulation of defense response GO:0031348 47 0.081
negative regulation of protein transport GO:0051224 75 0.080
regulation of cytokine production GO:0001817 232 0.080
regulation of sterol transport GO:0032371 21 0.080
negative regulation of cellular component movement GO:0051271 106 0.080
negative regulation of catalytic activity GO:0043086 335 0.080
acylglycerol catabolic process GO:0046464 12 0.079
secretion GO:0046903 254 0.079
negative regulation of dendritic spine development GO:0061000 1 0.078
protein localization to membrane GO:0072657 160 0.078
carbohydrate derivative biosynthetic process GO:1901137 207 0.078
tube development GO:0035295 125 0.077
tissue regeneration GO:0042246 3 0.077
negative regulation of phosphate metabolic process GO:0045936 267 0.077
protein oxidation GO:0018158 5 0.077
regulation of wound healing GO:0061041 56 0.076
carboxylic acid biosynthetic process GO:0046394 97 0.076
regulation of heterotypic cell cell adhesion GO:0034114 14 0.076
negative regulation of protein metabolic process GO:0051248 391 0.076
posttranscriptional regulation of gene expression GO:0010608 213 0.073
regulation of secretion GO:0051046 194 0.073
cholesterol homeostasis GO:0042632 28 0.072
cgmp mediated signaling GO:0019934 5 0.071
regulation of cell motility GO:2000145 299 0.071
nervous system development GO:0007399 293 0.071
cellular response to hydrogen peroxide GO:0070301 37 0.071
inflammatory response GO:0006954 79 0.070
secretion by cell GO:0032940 226 0.070
regulation of response to external stimulus GO:0032101 222 0.069
positive regulation of actin filament bundle assembly GO:0032233 25 0.069
taxis GO:0042330 157 0.068
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.068
negative regulation of cellular protein metabolic process GO:0032269 353 0.068
ion homeostasis GO:0050801 230 0.068
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.068
epithelial cell migration GO:0010631 119 0.068
positive regulation of proteolysis GO:0045862 142 0.068
negative regulation of lipid transport GO:0032369 18 0.067
post embryonic development GO:0009791 2 0.067
negative regulation of phosphorus metabolic process GO:0010563 267 0.067
regulation of inflammatory response GO:0050727 46 0.067
regulation of protein secretion GO:0050708 86 0.067
regulation of ras protein signal transduction GO:0046578 155 0.066
single organism membrane organization GO:0044802 268 0.066
organic acid biosynthetic process GO:0016053 97 0.066
negative regulation of protein secretion GO:0050709 29 0.066
cytokine secretion GO:0050663 64 0.065
regulation of immune effector process GO:0002697 91 0.065
positive regulation of lipase activity GO:0060193 28 0.065
phospholipid homeostasis GO:0055091 6 0.065
steroid biosynthetic process GO:0006694 46 0.065
negative regulation of response to wounding GO:1903035 47 0.065
interleukin 1 beta production GO:0032611 22 0.065
innate immune response GO:0045087 178 0.064
enzyme linked receptor protein signaling pathway GO:0007167 303 0.064
regulation of proteolysis GO:0030162 293 0.064
negative regulation of cell adhesion GO:0007162 64 0.064
negative regulation of lipid metabolic process GO:0045833 38 0.064
negative regulation of complement activation lectin pathway GO:0001869 2 0.064
n methyl d aspartate receptor clustering GO:0097114 1 0.063
regulation of transferase activity GO:0051338 355 0.063
negative regulation of cell motility GO:2000146 104 0.063
negative regulation of developmental process GO:0051093 247 0.063
negative regulation of secretion GO:0051048 58 0.062
actin cytoskeleton organization GO:0030036 207 0.062
positive regulation of cellular amine metabolic process GO:0033240 7 0.062
regulation of ion transport GO:0043269 189 0.062
regulation of purine nucleotide metabolic process GO:1900542 264 0.062
negative regulation of response to external stimulus GO:0032102 83 0.061
cellular amino acid metabolic process GO:0006520 116 0.061
regulation of protein kinase activity GO:0045859 289 0.061
system process GO:0003008 349 0.060
immune effector process GO:0002252 159 0.060
stress fiber assembly GO:0043149 40 0.060
positive regulation of transferase activity GO:0051347 227 0.060
organic acid transport GO:0015849 65 0.059
cellular protein catabolic process GO:0044257 261 0.059
regulation of nucleotide metabolic process GO:0006140 269 0.059
cell morphogenesis GO:0000902 296 0.059
negative regulation of cellular component organization GO:0051129 235 0.059
regulation of body fluid levels GO:0050878 99 0.059
regulation of protein catabolic process GO:0042176 155 0.058
monocarboxylic acid biosynthetic process GO:0072330 67 0.058
ameboidal type cell migration GO:0001667 135 0.058
single organism cell adhesion GO:0098602 179 0.057
amyloid precursor protein catabolic process GO:0042987 12 0.057
regulation of cytokine secretion involved in immune response GO:0002739 7 0.057
lipid transport GO:0006869 90 0.057
cell adhesion GO:0007155 325 0.057
regulation of secretion by cell GO:1903530 177 0.057
positive regulation of cell death GO:0010942 263 0.056
negative regulation of ion transport GO:0043271 39 0.056
positive regulation of transport GO:0051050 336 0.056
negative regulation of immune response GO:0050777 40 0.056
regulation of actin filament based process GO:0032970 141 0.056
positive regulation of organelle organization GO:0010638 195 0.056
monocarboxylic acid transport GO:0015718 32 0.056
regulation of small gtpase mediated signal transduction GO:0051056 156 0.055
heterotypic cell cell adhesion GO:0034113 28 0.054
cellular response to cytokine stimulus GO:0071345 181 0.054
organic hydroxy compound biosynthetic process GO:1901617 71 0.054
regulation of lipid metabolic process GO:0019216 96 0.054
epithelial cell proliferation GO:0050673 128 0.053
negative regulation of cell death GO:0060548 345 0.053
regulation of coagulation GO:0050818 44 0.053
organic hydroxy compound metabolic process GO:1901615 147 0.053
lipid modification GO:0030258 84 0.053
negative regulation of interleukin 1 beta production GO:0032691 6 0.053
receptor metabolic process GO:0043112 81 0.053
cytokine mediated signaling pathway GO:0019221 109 0.051
cellular response to oxygen containing compound GO:1901701 276 0.051
protein secretion GO:0009306 98 0.051
endothelial cell migration GO:0043542 86 0.051
wound healing GO:0042060 115 0.051
negative regulation of phosphorylation GO:0042326 174 0.051
digestive tract morphogenesis GO:0048546 56 0.051
regulation of anion transport GO:0044070 25 0.051
regulation of map kinase activity GO:0043405 108 0.050
regulation of cell activation GO:0050865 125 0.050
glycerolipid biosynthetic process GO:0045017 51 0.050
platelet activation GO:0030168 44 0.050
regulation of cytoskeleton organization GO:0051493 177 0.050
regulation of cellular component movement GO:0051270 334 0.050
lipid localization GO:0010876 106 0.049
regulation of high density lipoprotein particle clearance GO:0010982 2 0.049
sterol transmembrane transport GO:0035382 4 0.049
response to oxygen containing compound GO:1901700 369 0.049
triglyceride rich lipoprotein particle clearance GO:0071830 4 0.049
regulation of phospholipid transport GO:2001138 4 0.049
vesicle mediated transport GO:0016192 371 0.048
interleukin 1 secretion GO:0050701 18 0.048
organonitrogen compound biosynthetic process GO:1901566 200 0.048
cholesterol metabolic process GO:0008203 28 0.048
peptide metabolic process GO:0006518 51 0.048
cellular amide metabolic process GO:0043603 69 0.048
regulation of kinase activity GO:0043549 314 0.048
regulation of anatomical structure morphogenesis GO:0022603 286 0.047
actin filament based process GO:0030029 224 0.047
negative regulation of cytokine production GO:0001818 82 0.047
phospholipid metabolic process GO:0006644 99 0.047
chemical homeostasis GO:0048878 306 0.047
negative regulation of intracellular signal transduction GO:1902532 183 0.047
regulation of cellular amino acid metabolic process GO:0006521 6 0.046
positive regulation of fatty acid biosynthetic process GO:0045723 5 0.046
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.046
positive regulation of cytoskeleton organization GO:0051495 83 0.046
negative regulation of protein phosphorylation GO:0001933 140 0.046
positive regulation of protein catabolic process GO:0045732 75 0.046
negative regulation of multicellular organismal process GO:0051241 317 0.046
cytokine production involved in immune response GO:0002367 27 0.045
maintenance of location GO:0051235 112 0.045
endothelial cell proliferation GO:0001935 65 0.045
protein import GO:0017038 130 0.045
negative regulation of epithelial cell migration GO:0010633 38 0.045
cell activation GO:0001775 213 0.044
positive regulation of cell adhesion GO:0045785 84 0.044
positive regulation of phospholipid transport GO:2001140 4 0.044
blood vessel endothelial cell migration GO:0043534 42 0.044
long chain fatty acid transport GO:0015909 18 0.044
positive regulation of membrane protein ectodomain proteolysis GO:0051044 13 0.043
response to wounding GO:0009611 168 0.043
second messenger mediated signaling GO:0019932 78 0.043
protein maturation GO:0051604 233 0.043
positive regulation of steroid metabolic process GO:0045940 13 0.043
regulation of interleukin 1 production GO:0032652 21 0.042
membrane protein proteolysis GO:0033619 38 0.042
regulation of protein localization GO:0032880 296 0.042
regulation of cell cell adhesion involved in gastrulation GO:0070587 6 0.041
negative regulation of protein modification process GO:0031400 200 0.041
response to oxidative stress GO:0006979 121 0.041
regulation of stress fiber assembly GO:0051492 32 0.041
single organismal cell cell adhesion GO:0016337 148 0.041
regulation of hemostasis GO:1900046 42 0.041
interleukin 1 production GO:0032612 26 0.041
negative regulation of blood coagulation GO:0030195 22 0.041
leukocyte cell cell adhesion GO:0007159 37 0.041
negative chemotaxis GO:0050919 11 0.040
membrane protein ectodomain proteolysis GO:0006509 33 0.040
mapk cascade GO:0000165 288 0.039
multicellular organismal aging GO:0010259 3 0.039
negative regulation of cell differentiation GO:0045596 171 0.039
regulation of cell development GO:0060284 161 0.039
response to hydrogen peroxide GO:0042542 40 0.039
sterol metabolic process GO:0016125 28 0.039
positive regulation of developmental process GO:0051094 314 0.039
inclusion body assembly GO:0070841 17 0.038
positive regulation of substrate adhesion dependent cell spreading GO:1900026 15 0.038
regulation of low density lipoprotein particle receptor catabolic process GO:0032803 2 0.038
removal of superoxide radicals GO:0019430 6 0.038
gastrulation GO:0007369 51 0.038
blood coagulation GO:0007596 76 0.038
cellular response to reactive oxygen species GO:0034614 50 0.038
positive regulation of lipid biosynthetic process GO:0046889 22 0.038
female gamete generation GO:0007292 2 0.038
intestinal cholesterol absorption GO:0030299 4 0.037
positive regulation of phosphorylation GO:0042327 394 0.037
coagulation GO:0050817 78 0.037
actin filament organization GO:0007015 128 0.037
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.037
neuron projection development GO:0031175 106 0.037
regulation of lipid biosynthetic process GO:0046890 47 0.037
regulation of interleukin 1 beta production GO:0032651 18 0.037
protein lipid complex assembly GO:0065005 12 0.036
Mouse
cell projection organization GO:0030030 252 0.036
regulation of interleukin 1 secretion GO:0050704 14 0.036
negative regulation of catabolic process GO:0009895 104 0.036
regulation of cell morphogenesis GO:0022604 153 0.036
positive regulation of ion transport GO:0043270 87 0.036
regulation of cell substrate adhesion GO:0010810 68 0.036
tube morphogenesis GO:0035239 95 0.036
regulation of epithelial cell migration GO:0010632 93 0.036
negative regulation of transferase activity GO:0051348 124 0.035
regulation of cytokine mediated signaling pathway GO:0001959 41 0.035
cholesterol efflux GO:0033344 28 0.035
cell development GO:0048468 328 0.035
regulation of lipid transport GO:0032368 44 0.035
fatty acid transport GO:0015908 25 0.035
regulation of cellular protein catabolic process GO:1903362 96 0.035
glycerophospholipid biosynthetic process GO:0046474 40 0.035
cellular response to tumor necrosis factor GO:0071356 63 0.034
signal transduction by phosphorylation GO:0023014 297 0.034
regulation of cell projection organization GO:0031344 107 0.034
substrate adhesion dependent cell spreading GO:0034446 41 0.034
hydrogen peroxide metabolic process GO:0042743 20 0.034
negative regulation of transport GO:0051051 176 0.034
reactive oxygen species metabolic process GO:0072593 75 0.034
regulation of blood vessel endothelial cell migration GO:0043535 30 0.034
low density lipoprotein particle receptor catabolic process GO:0032802 3 0.033
regulation of steroid biosynthetic process GO:0050810 23 0.033
intestinal absorption GO:0050892 4 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
gland development GO:0048732 48 0.033
phospholipid biosynthetic process GO:0008654 44 0.033
amyloid precursor protein metabolic process GO:0042982 17 0.033
negative regulation of kinase activity GO:0033673 106 0.033
positive regulation of cell development GO:0010720 92 0.033
integrin mediated signaling pathway GO:0007229 32 0.033
hemostasis GO:0007599 76 0.032
negative regulation of secretion by cell GO:1903531 52 0.032
negative regulation of cytokine secretion GO:0050710 20 0.032
regulation of alcohol biosynthetic process GO:1902930 22 0.032
determination of adult lifespan GO:0008340 2 0.032
regulation of epithelial cell proliferation GO:0050678 113 0.032
interleukin 1 beta secretion GO:0050702 15 0.032
negative regulation of response to cytokine stimulus GO:0060761 25 0.032
regulation of cellular amine metabolic process GO:0033238 11 0.031
response to cytokine GO:0034097 232 0.031
positive regulation of cytokine production GO:0001819 167 0.031
organic hydroxy compound transport GO:0015850 63 0.031
response to reactive oxygen species GO:0000302 61 0.031
anion homeostasis GO:0055081 18 0.031
cyclic nucleotide mediated signaling GO:0019935 26 0.030
oogenesis GO:0048477 2 0.030
locomotory behavior GO:0007626 1 0.030
negative regulation of beta amyloid formation GO:1902430 3 0.030
neuron differentiation GO:0030182 138 0.030
cytokine secretion involved in immune response GO:0002374 7 0.030
positive regulation of cell differentiation GO:0045597 211 0.030
positive regulation of cellular protein catabolic process GO:1903364 37 0.030
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.030
positive regulation of cell projection organization GO:0031346 64 0.030
negative regulation of cytokine production involved in immune response GO:0002719 13 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.029
digestion GO:0007586 22 0.029
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.029
negative regulation of protein activation cascade GO:2000258 7 0.029
positive regulation of lipid transport GO:0032370 22 0.029
regulation of response to cytokine stimulus GO:0060759 46 0.029
positive regulation of oxidoreductase activity GO:0051353 26 0.028
regulation of cgmp biosynthetic process GO:0030826 4 0.028
segmentation GO:0035282 4 0.028
positive regulation of triglyceride metabolic process GO:0090208 9 0.028
positive regulation of lipid catabolic process GO:0050996 13 0.028
digestive system development GO:0055123 75 0.028
purine ribonucleoside metabolic process GO:0046128 437 0.028
chemotaxis GO:0006935 157 0.027
ribonucleoside triphosphate metabolic process GO:0009199 412 0.027
purine nucleotide catabolic process GO:0006195 405 0.027
regulation of protein stability GO:0031647 87 0.027
protein processing GO:0016485 226 0.027
dephosphorylation GO:0016311 209 0.027
fatty acid homeostasis GO:0055089 3 0.027
regulation of protein maturation GO:1903317 150 0.027
neuron death GO:0070997 65 0.027
regulation of macrophage chemotaxis GO:0010758 4 0.027
growth GO:0040007 202 0.027
embryonic morphogenesis GO:0048598 85 0.026
nucleoside triphosphate metabolic process GO:0009141 422 0.026
regulation of nervous system development GO:0051960 88 0.026
apoptotic signaling pathway GO:0097190 268 0.026
nucleoside triphosphate catabolic process GO:0009143 394 0.026
hydrogen peroxide catabolic process GO:0042744 13 0.026
regulation of actin cytoskeleton organization GO:0032956 116 0.026
negative regulation of very low density lipoprotein particle remodeling GO:0010903 3 0.026
steroid esterification GO:0034433 10 0.026
ribonucleoside catabolic process GO:0042454 406 0.026
response to tumor necrosis factor GO:0034612 76 0.026
regulation of digestive system process GO:0044058 5 0.025
positive regulation of cell substrate adhesion GO:0010811 37 0.025
positive regulation of nucleotide catabolic process GO:0030813 185 0.025
negative regulation of protein kinase activity GO:0006469 98 0.025
negative regulation of inflammatory response GO:0050728 22 0.025
glycosyl compound catabolic process GO:1901658 413 0.025
alcohol metabolic process GO:0006066 114 0.025
purine nucleoside triphosphate catabolic process GO:0009146 392 0.025
positive regulation of stress fiber assembly GO:0051496 22 0.024
endocytosis GO:0006897 159 0.024
regulation of amyloid precursor protein catabolic process GO:1902991 9 0.024
regulation of lipase activity GO:0060191 37 0.024
negative regulation of endothelial cell migration GO:0010596 29 0.024
negative regulation of coagulation GO:0050819 24 0.024
nucleotide catabolic process GO:0009166 408 0.024
cellular component morphogenesis GO:0032989 314 0.024
purine containing compound catabolic process GO:0072523 411 0.024
epithelium migration GO:0090132 119 0.024
tumor necrosis factor mediated signaling pathway GO:0033209 27 0.024
beta amyloid formation GO:0034205 7 0.024
cellular response to superoxide GO:0071451 6 0.023
endocrine system development GO:0035270 26 0.023
purine nucleoside catabolic process GO:0006152 398 0.023
neuromuscular junction development GO:0007528 3 0.023
cell substrate adhesion GO:0031589 132 0.023
peripheral nervous system development GO:0007422 2 0.023
regulation of cell adhesion GO:0030155 166 0.023
negative regulation of neuron differentiation GO:0045665 21 0.023
positive regulation of protein phosphorylation GO:0001934 313 0.023
regulation of actin filament bundle assembly GO:0032231 36 0.023
negative regulation of heterotypic cell cell adhesion GO:0034115 6 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.023
regulation of steroid metabolic process GO:0019218 32 0.023
regulation of plasma lipoprotein particle levels GO:0097006 32 0.023
ribonucleoside triphosphate catabolic process GO:0009203 391 0.023
neuron development GO:0048666 113 0.023
regulation of beta amyloid clearance GO:1900221 5 0.023
organ or tissue specific immune response GO:0002251 22 0.022
cgmp metabolic process GO:0046068 19 0.022
lipid digestion GO:0044241 6 0.022
regulation of protein processing GO:0070613 150 0.022

LCAT disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.279
acquired metabolic disease DOID:0060158 58 0.120
central nervous system disease DOID:331 186 0.042
nervous system disease DOID:863 431 0.042
neurodegenerative disease DOID:1289 102 0.036
amyloidosis DOID:9120 10 0.029