Homo sapiens

17 known processes

LIG1

ligase I, DNA, ATP-dependent

(Aliases: MGC117397,MGC130025)

LIG1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multicellular organismal aging GO:0010259 3 0.225
determination of adult lifespan GO:0008340 2 0.200
dna repair GO:0006281 198 0.189
Yeast Mouse
microtubule based process GO:0007017 210 0.178
dna dependent dna replication GO:0006261 44 0.154
Yeast
mitotic cell cycle process GO:1903047 286 0.154
base excision repair GO:0006284 21 0.150
Yeast
double strand break repair GO:0006302 101 0.147
Mouse
nucleotide excision repair GO:0006289 31 0.143
Yeast
dna recombination GO:0006310 77 0.136
Yeast
cellular response to dna damage stimulus GO:0006974 379 0.134
Yeast Mouse
meiosis i GO:0007127 4 0.133
mitotic cell cycle GO:0000278 326 0.125
Yeast
post embryonic development GO:0009791 2 0.121
microtubule organizing center organization GO:0031023 62 0.116
dna replication GO:0006260 116 0.111
Yeast Mouse
microtubule cytoskeleton organization GO:0000226 176 0.096
dna synthesis involved in dna repair GO:0000731 6 0.095
negative regulation of chromatin silencing GO:0031936 4 0.085
purine nucleoside monophosphate catabolic process GO:0009128 158 0.085
mitotic cell cycle phase transition GO:0044772 162 0.081
regulation of cell cycle process GO:0010564 266 0.080
ribonucleoside triphosphate catabolic process GO:0009203 391 0.079
ribonucleotide catabolic process GO:0009261 405 0.074
centrosome organization GO:0051297 58 0.072
cellular amino acid metabolic process GO:0006520 116 0.068
chromosome segregation GO:0007059 114 0.068
dna strand elongation GO:0022616 5 0.065
Yeast
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.065
nucleoside monophosphate metabolic process GO:0009123 191 0.061
embryo development GO:0009790 123 0.060
Worm
female gamete generation GO:0007292 2 0.060
reproductive process GO:0022414 106 0.058
dna biosynthetic process GO:0071897 40 0.056
chromatin modification GO:0016568 298 0.055
nucleoside phosphate catabolic process GO:1901292 412 0.054
meiotic chromosome segregation GO:0045132 4 0.051
organelle fission GO:0048285 149 0.050
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.050
ribonucleoside triphosphate metabolic process GO:0009199 412 0.050
nuclear division GO:0000280 128 0.048
organophosphate catabolic process GO:0046434 430 0.047
purine nucleotide catabolic process GO:0006195 405 0.046
atp catabolic process GO:0006200 157 0.045
regulation of cell cycle GO:0051726 393 0.044
regulation of chromosome segregation GO:0051983 44 0.043
nucleoside triphosphate catabolic process GO:0009143 394 0.043
cell cycle phase transition GO:0044770 173 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.040
chromatin organization GO:0006325 351 0.039
oogenesis GO:0048477 2 0.039
regulation of intracellular transport GO:0032386 195 0.039
regulation of mitotic cell cycle GO:0007346 189 0.038
negative regulation of mitotic cell cycle GO:0045930 102 0.038
male meiosis GO:0007140 1 0.037
dna conformation change GO:0071103 113 0.037
deoxyribose phosphate metabolic process GO:0019692 6 0.037
response to abiotic stimulus GO:0009628 336 0.034
hematopoietic or lymphoid organ development GO:0048534 186 0.033
glycosyl compound catabolic process GO:1901658 413 0.033
purine containing compound catabolic process GO:0072523 411 0.031
purine nucleoside catabolic process GO:0006152 398 0.029
atp metabolic process GO:0046034 176 0.029
embryo development ending in birth or egg hatching GO:0009792 34 0.029
Worm
ribonucleoside catabolic process GO:0042454 406 0.029
single organism reproductive process GO:0044702 98 0.029
covalent chromatin modification GO:0016569 254 0.028
negative regulation of cell cycle GO:0045786 193 0.028
nucleoside catabolic process GO:0009164 408 0.028
response to ionizing radiation GO:0010212 65 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
purine ribonucleotide catabolic process GO:0009154 404 0.028
regulation of cellular ketone metabolic process GO:0010565 50 0.028
purine ribonucleoside metabolic process GO:0046128 437 0.027
lymphocyte activation GO:0046649 133 0.027
positive regulation of hydrolase activity GO:0051345 331 0.026
blastocyst development GO:0001824 3 0.026
meiotic chromosome separation GO:0051307 3 0.026
purine nucleoside triphosphate catabolic process GO:0009146 392 0.026
mitotic cell cycle checkpoint GO:0007093 68 0.025
immune effector process GO:0002252 159 0.025
developmental process involved in reproduction GO:0003006 66 0.025
vesicle mediated transport GO:0016192 371 0.025
Worm
protein alkylation GO:0008213 74 0.025
establishment of nucleus localization GO:0040023 1 0.024
nucleotide catabolic process GO:0009166 408 0.023
nucleoside triphosphate metabolic process GO:0009141 422 0.023
regulation of cellular amino acid metabolic process GO:0006521 6 0.023
methylation GO:0032259 106 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.022
nucleoside monophosphate catabolic process GO:0009125 159 0.022
dna damage checkpoint GO:0000077 68 0.022
cell cycle checkpoint GO:0000075 117 0.022
cell projection morphogenesis GO:0048858 129 0.022
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.022
response to fungus GO:0009620 4 0.021
purine nucleoside triphosphate metabolic process GO:0009144 412 0.021
interspecies interaction between organisms GO:0044419 156 0.021
cellular component morphogenesis GO:0032989 314 0.021
sister chromatid segregation GO:0000819 54 0.021
cellular ketone metabolic process GO:0042180 80 0.021
positive regulation of cellular amine metabolic process GO:0033240 7 0.021
negative regulation of cell cycle process GO:0010948 121 0.021
ribonucleoside monophosphate metabolic process GO:0009161 187 0.021
oocyte differentiation GO:0009994 2 0.021
reproduction GO:0000003 63 0.021
sensory organ development GO:0007423 52 0.020
positive regulation of nuclease activity GO:0032075 5 0.020
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.020
spindle organization GO:0007051 53 0.020
epithelium development GO:0060429 227 0.020
cellular response to endogenous stimulus GO:0071495 336 0.019
mitotic nuclear division GO:0007067 119 0.019
ribonucleoside monophosphate catabolic process GO:0009158 158 0.019
reproductive structure development GO:0048608 55 0.019
endomembrane system organization GO:0010256 196 0.019
sex differentiation GO:0007548 45 0.019
response to other organism GO:0051707 261 0.019
protein modification by small protein conjugation GO:0032446 342 0.018
organ morphogenesis GO:0009887 147 0.018
response to hormone GO:0009725 175 0.018
nervous system development GO:0007399 293 0.018
regulation of establishment of protein localization GO:0070201 242 0.018
immune system development GO:0002520 195 0.018
rna phosphodiester bond hydrolysis GO:0090501 35 0.018
regulation of response to dna damage stimulus GO:2001020 94 0.017
purine ribonucleoside catabolic process GO:0046130 398 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
multi organism cellular process GO:0044764 156 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
positive regulation of transport GO:0051050 336 0.017
regulation of gene expression epigenetic GO:0040029 73 0.017
cell division GO:0051301 168 0.017
cell projection organization GO:0030030 252 0.017
rna catabolic process GO:0006401 71 0.017
response to uv GO:0009411 73 0.017
cell part morphogenesis GO:0032990 137 0.017
cellular amine metabolic process GO:0044106 41 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.017
regulation of transcription by chromatin organization GO:0034401 1 0.017
response to external biotic stimulus GO:0043207 261 0.017
chromatin remodeling GO:0006338 55 0.016
immune response GO:0006955 307 0.016
viral life cycle GO:0019058 132 0.016
regulation of immune effector process GO:0002697 91 0.016
response to organic cyclic compound GO:0014070 204 0.016
response to growth factor GO:0070848 205 0.016
protein dna complex subunit organization GO:0071824 80 0.016
response to biotic stimulus GO:0009607 276 0.016
rna processing GO:0006396 255 0.016
regulation of cellular component biogenesis GO:0044087 281 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
regulation of cellular amine metabolic process GO:0033238 11 0.015
gtp metabolic process GO:0046039 239 0.015
mitochondrion organization GO:0007005 156 0.015
membrane organization GO:0061024 292 0.015
regulation of secretion by cell GO:1903530 177 0.015
regulation of protein localization GO:0032880 296 0.015
chromatin silencing GO:0006342 12 0.015
hemopoiesis GO:0030097 180 0.015
regulation of multi organism process GO:0043900 157 0.015
negative regulation of cell cycle phase transition GO:1901988 89 0.015
nucleus localization GO:0051647 1 0.015
maintenance of location GO:0051235 112 0.014
dephosphorylation GO:0016311 209 0.014
regulation of cell cycle phase transition GO:1901987 126 0.014
deoxyribonucleotide metabolic process GO:0009262 6 0.014
chemical homeostasis GO:0048878 306 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
cilium organization GO:0044782 68 0.014
centrosome cycle GO:0007098 32 0.014
nucleus organization GO:0006997 28 0.013
mitotic sister chromatid segregation GO:0000070 53 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
positive regulation of cell activation GO:0050867 81 0.013
gene conversion GO:0035822 1 0.013
negative regulation of cell death GO:0060548 345 0.013
response to organophosphorus GO:0046683 41 0.013
cell activation GO:0001775 213 0.013
dna integrity checkpoint GO:0031570 71 0.013
aging GO:0007568 66 0.013
neuron development GO:0048666 113 0.013
multi organism reproductive process GO:0044703 54 0.013
single organism cellular localization GO:1902580 332 0.013
dna strand elongation involved in dna replication GO:0006271 3 0.013
Yeast
regulation of immune response GO:0050776 201 0.012
nucleosome organization GO:0034728 66 0.012
autophagy GO:0006914 88 0.012
regulation of protein transport GO:0051223 213 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
amine metabolic process GO:0009308 44 0.012
histone methylation GO:0016571 60 0.012
cell cycle g1 s phase transition GO:0044843 80 0.012
response to nitrogen compound GO:1901698 184 0.012
cell development GO:0048468 328 0.012
endocytosis GO:0006897 159 0.012
Worm
organelle assembly GO:0070925 176 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
positive regulation of cellular component movement GO:0051272 181 0.012
convergent extension GO:0060026 1 0.012
positive regulation of developmental process GO:0051094 314 0.011
translesion synthesis GO:0019985 8 0.011
regulation of mapk cascade GO:0043408 262 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.011
protein localization to organelle GO:0033365 280 0.011
gene silencing GO:0016458 49 0.011
growth GO:0040007 202 0.011
macromolecule methylation GO:0043414 97 0.011
protein localization to nucleus GO:0034504 136 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
response to transforming growth factor beta GO:0071559 94 0.011
regulation of energy homeostasis GO:2000505 1 0.011
positive regulation of cell cycle process GO:0090068 106 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
lagging strand elongation GO:0006273 3 0.011
Yeast
maintenance of protein location in cell GO:0032507 56 0.011
pharynx development GO:0060465 1 0.011
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.010
nucleotide biosynthetic process GO:0009165 109 0.010
leukocyte activation GO:0045321 164 0.010
spindle assembly GO:0051225 29 0.010
2 deoxyribonucleotide metabolic process GO:0009394 6 0.010
eye development GO:0001654 42 0.010
regulation of microtubule cytoskeleton organization GO:0070507 61 0.010
cellular component assembly involved in morphogenesis GO:0010927 73 0.010
alpha amino acid metabolic process GO:1901605 72 0.010

LIG1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.117
disease of cellular proliferation DOID:14566 174 0.117
organ system cancer DOID:0050686 164 0.106
gastrointestinal system cancer DOID:3119 52 0.058
large intestine cancer DOID:5672 29 0.015
intestinal cancer DOID:10155 29 0.015
colorectal cancer DOID:9256 29 0.015
musculoskeletal system disease DOID:17 223 0.011