Homo sapiens

0 known processes

LRP1

low density lipoprotein receptor-related protein 1

(Aliases: APOER,FLJ16451,TGFBR5,APR,A2MR,MGC88725,CD91,IGFBP3R,LRP)

LRP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
visual learning GO:0008542 1 0.850
histone h4 acetylation GO:0043967 47 0.789
positive regulation of secretion by cell GO:1903532 108 0.765
vesicle mediated transport GO:0016192 371 0.754
Human Mouse
negative regulation of neuron differentiation GO:0045665 21 0.702
regulation of protein localization GO:0032880 296 0.654
Human
negative regulation of multicellular organismal process GO:0051241 317 0.639
Human
regulation of locomotion GO:0040012 329 0.628
Mouse
regulation of protein secretion GO:0050708 86 0.605
positive regulation of locomotion GO:0040017 186 0.595
chemotaxis GO:0006935 157 0.589
double strand break repair GO:0006302 101 0.565
negative regulation of developmental process GO:0051093 247 0.560
Human
taxis GO:0042330 157 0.550
secretion GO:0046903 254 0.541
Human
positive regulation of transport GO:0051050 336 0.529
Human Mouse
regulation of protein transport GO:0051223 213 0.527
Human
internal protein amino acid acetylation GO:0006475 101 0.490
regulation of cell migration GO:0030334 289 0.474
Mouse
cardiovascular system development GO:0072358 262 0.469
Human Mouse
vasculature development GO:0001944 181 0.451
Human Mouse
secretion by cell GO:0032940 226 0.451
positive regulation of response to dna damage stimulus GO:2001022 43 0.448
cell substrate adhesion GO:0031589 132 0.443
cholesterol homeostasis GO:0042632 28 0.439
Human
regulation of cell development GO:0060284 161 0.434
cell development GO:0048468 328 0.428
Human
lipid metabolic process GO:0006629 381 0.418
Mouse
histone modification GO:0016570 251 0.415
visual behavior GO:0007632 2 0.404
internal peptidyl lysine acetylation GO:0018393 97 0.374
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.374
Human Mouse
positive regulation of protein secretion GO:0050714 60 0.367
extracellular structure organization GO:0043062 41 0.366
regulation of secretion by cell GO:1903530 177 0.366
protein secretion GO:0009306 98 0.362
response to metal ion GO:0010038 84 0.360
extracellular matrix organization GO:0030198 41 0.355
negative regulation of catalytic activity GO:0043086 335 0.353
Human
regulation of cell motility GO:2000145 299 0.352
Mouse
chromatin modification GO:0016568 298 0.350
regulation of vesicle mediated transport GO:0060627 130 0.342
cellular response to endogenous stimulus GO:0071495 336 0.340
cellular response to growth factor stimulus GO:0071363 197 0.340
cellular component morphogenesis GO:0032989 314 0.334
Human
sterol homeostasis GO:0055092 28 0.332
Human
glycerol metabolic process GO:0006071 4 0.330
response to radiation GO:0009314 151 0.316
regulation of lipid catabolic process GO:0050994 23 0.309
positive regulation of dna metabolic process GO:0051054 73 0.308
response to abiotic stimulus GO:0009628 336 0.304
regulation of cellular component movement GO:0051270 334 0.302
Mouse
growth GO:0040007 202 0.293
system process GO:0003008 349 0.293
Human
cellular response to dna damage stimulus GO:0006974 379 0.288
dna repair GO:0006281 198 0.285
negative regulation of cell differentiation GO:0045596 171 0.285
Human
protein processing GO:0016485 226 0.278
regulation of cell adhesion GO:0030155 166 0.274
negative regulation of hydrolase activity GO:0051346 182 0.273
single organismal cell cell adhesion GO:0016337 148 0.268
biological adhesion GO:0022610 331 0.260
single organism carbohydrate metabolic process GO:0044723 193 0.257
Human
single organism cell adhesion GO:0098602 179 0.256
positive regulation of cellular component movement GO:0051272 181 0.254
protein acetylation GO:0006473 116 0.251
cellular amine metabolic process GO:0044106 41 0.249
enzyme linked receptor protein signaling pathway GO:0007167 303 0.247
Human Mouse
negative regulation of neurogenesis GO:0050768 26 0.245
cholesterol metabolic process GO:0008203 28 0.244
Mouse
regulation of neuron differentiation GO:0045664 70 0.244
regulation of dna repair GO:0006282 47 0.242
response to wounding GO:0009611 168 0.241
histone acetylation GO:0016573 93 0.238
negative regulation of cell death GO:0060548 345 0.237
Human
positive regulation of cell migration GO:0030335 172 0.236
regulation of establishment of protein localization GO:0070201 242 0.234
Human
regulation of cellular response to stress GO:0080135 244 0.234
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.230
regulation of cell cycle GO:0051726 393 0.230
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.224
positive regulation of secretion GO:0051047 116 0.224
response to growth factor GO:0070848 205 0.218
positive regulation of programmed cell death GO:0043068 249 0.213
nervous system development GO:0007399 293 0.213
cytokine production GO:0001816 247 0.206
anatomical structure formation involved in morphogenesis GO:0048646 284 0.204
Human
cell cycle arrest GO:0007050 71 0.202
ionotropic glutamate receptor signaling pathway GO:0035235 16 0.199
cell adhesion GO:0007155 325 0.198
positive regulation of immune system process GO:0002684 283 0.194
regulation of nervous system development GO:0051960 88 0.191
covalent chromatin modification GO:0016569 254 0.189
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.188
protein localization to membrane GO:0072657 160 0.187
peptidyl lysine acetylation GO:0018394 101 0.184
regulation of growth GO:0040008 165 0.181
defense response GO:0006952 315 0.181
cell matrix adhesion GO:0007160 85 0.180
regulation of heterotypic cell cell adhesion GO:0034114 14 0.179
positive regulation of cell motility GO:2000147 177 0.177
neurogenesis GO:0022008 169 0.172
negative regulation of cell development GO:0010721 48 0.163
positive regulation of cell death GO:0010942 263 0.163
negative regulation of locomotion GO:0040013 118 0.163
Mouse
negative regulation of wound healing GO:0061045 25 0.160
response to transition metal nanoparticle GO:1990267 29 0.158
membrane organization GO:0061024 292 0.158
protein acylation GO:0043543 138 0.157
regulation of neurogenesis GO:0050767 82 0.153
response to light stimulus GO:0009416 87 0.152
chemical homeostasis GO:0048878 306 0.147
Human
ossification GO:0001503 121 0.147
Human
circulatory system development GO:0072359 262 0.147
Human Mouse
positive regulation of dna repair GO:0045739 25 0.144
chromatin organization GO:0006325 351 0.142
behavior GO:0007610 112 0.141
cell projection organization GO:0030030 252 0.141
blood vessel development GO:0001568 172 0.140
Human Mouse
negative regulation of cellular component organization GO:0051129 235 0.140
phospholipid metabolic process GO:0006644 99 0.139
cell growth GO:0016049 160 0.136
neuron projection development GO:0031175 106 0.136
steroid metabolic process GO:0008202 94 0.133
Mouse
regulation of response to dna damage stimulus GO:2001020 94 0.133
organophosphate catabolic process GO:0046434 430 0.130
cell part morphogenesis GO:0032990 137 0.128
neuron differentiation GO:0030182 138 0.125
response to oxidative stress GO:0006979 121 0.122
platelet activation GO:0030168 44 0.122
cellular protein catabolic process GO:0044257 261 0.122
phospholipid catabolic process GO:0009395 12 0.120
single organism membrane organization GO:0044802 268 0.119
positive regulation of cellular component organization GO:0051130 376 0.117
Human
regulation of angiogenesis GO:0045765 92 0.115
regulation of cell growth GO:0001558 135 0.113
signal transduction by phosphorylation GO:0023014 297 0.112
Human
regulation of protein catabolic process GO:0042176 155 0.111
regulation of vasculature development GO:1901342 97 0.109
innate immune response GO:0045087 178 0.109
regulation of transferase activity GO:0051338 355 0.105
Human
angiogenesis GO:0001525 147 0.105
Human
generation of neurons GO:0048699 152 0.105
positive regulation of developmental process GO:0051094 314 0.104
Human
response to inorganic substance GO:0010035 127 0.103
negative regulation of blood coagulation GO:0030195 22 0.100
cdc42 protein signal transduction GO:0032488 4 0.100
tube development GO:0035295 125 0.098
regulation of coagulation GO:0050818 44 0.098
heterotypic cell cell adhesion GO:0034113 28 0.098
peripheral nervous system development GO:0007422 2 0.097
negative regulation of protein processing GO:0010955 142 0.096
regulation of cytokine production GO:0001817 232 0.093
regulation of wound healing GO:0061041 56 0.092
g protein coupled receptor signaling pathway GO:0007186 207 0.091
regulation of endocytosis GO:0030100 72 0.091
regulation of cell cycle process GO:0010564 266 0.091
Human
anion homeostasis GO:0055081 18 0.090
positive regulation of phosphorylation GO:0042327 394 0.090
Human
lipid catabolic process GO:0016042 84 0.089
regulation of purine nucleotide metabolic process GO:1900542 264 0.089
positive regulation of vasoconstriction GO:0045907 3 0.089
neuron development GO:0048666 113 0.089
positive regulation of apoptotic process GO:0043065 246 0.088
axonogenesis GO:0007409 31 0.088
cell type specific apoptotic process GO:0097285 125 0.087
Human
innate immune response activating cell surface receptor signaling pathway GO:0002220 2 0.087
negative regulation of protein maturation GO:1903318 142 0.087
negative regulation of proteolysis GO:0045861 132 0.085
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.083
regulation of proteolysis GO:0030162 293 0.082
small gtpase mediated signal transduction GO:0007264 78 0.082
negative regulation of cell cycle GO:0045786 193 0.081
cellular lipid metabolic process GO:0044255 303 0.081
post embryonic development GO:0009791 2 0.081
cellular lipid catabolic process GO:0044242 65 0.079
extrinsic apoptotic signaling pathway GO:0097191 119 0.079
neurological system process GO:0050877 163 0.079
negative regulation of nervous system development GO:0051961 28 0.077
adult locomotory behavior GO:0008344 1 0.077
regulation of protein maturation GO:1903317 150 0.076
negative regulation of phosphorus metabolic process GO:0010563 267 0.074
Human
regulation of cell cell adhesion GO:0022407 57 0.074
cellular macromolecule catabolic process GO:0044265 380 0.074
regulation of cellular component biogenesis GO:0044087 281 0.074
negative regulation of cell adhesion GO:0007162 64 0.073
regulation of defense response GO:0031347 154 0.073
regulation of anatomical structure morphogenesis GO:0022603 286 0.072
protein catabolic process GO:0030163 325 0.072
determination of adult lifespan GO:0008340 2 0.072
regulation of ion transport GO:0043269 189 0.068
Human
positive regulation of interleukin 8 production GO:0032757 36 0.067
neuron migration GO:0001764 11 0.067
posttranscriptional regulation of gene expression GO:0010608 213 0.067
postsynaptic membrane organization GO:0001941 2 0.066
response to iron ion GO:0010039 6 0.066
cell chemotaxis GO:0060326 112 0.065
negative regulation of phosphate metabolic process GO:0045936 267 0.064
Human
regulation of tube size GO:0035150 18 0.062
regulation of nucleotide metabolic process GO:0006140 269 0.062
regulation of cellular response to growth factor stimulus GO:0090287 76 0.061
regulation of cellular amine metabolic process GO:0033238 11 0.061
epithelial cell migration GO:0010631 119 0.061
cellular response to oxygen containing compound GO:1901701 276 0.061
Human
negative regulation of cellular component movement GO:0051271 106 0.061
Mouse
complement activation GO:0006956 19 0.061
multicellular organismal aging GO:0010259 3 0.061
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.061
positive regulation of cell proliferation GO:0008284 301 0.060
Human
cation homeostasis GO:0055080 189 0.059
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.059
regulation of lipid metabolic process GO:0019216 96 0.059
plasma membrane organization GO:0007009 115 0.058
negative regulation of programmed cell death GO:0043069 321 0.058
Human
lipid localization GO:0010876 106 0.058
Mouse
cell morphogenesis GO:0000902 296 0.058
Human
digestive tract development GO:0048565 75 0.058
locomotory behavior GO:0007626 1 0.058
endothelial cell proliferation GO:0001935 65 0.057
regulation of mitotic cell cycle GO:0007346 189 0.057
Human
nitrogen compound transport GO:0071705 191 0.057
actin cytoskeleton organization GO:0030036 207 0.057
Mouse
carbohydrate metabolic process GO:0005975 207 0.057
Human
negative regulation of protein metabolic process GO:0051248 391 0.056
Human
glycerolipid metabolic process GO:0046486 107 0.055
organic hydroxy compound metabolic process GO:1901615 147 0.055
Mouse
regulation of cytokine secretion GO:0050707 57 0.055
negative regulation of cell migration GO:0030336 102 0.055
Mouse
interspecies interaction between organisms GO:0044419 156 0.055
divalent inorganic cation homeostasis GO:0072507 136 0.055
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.054
gland development GO:0048732 48 0.054
positive regulation of cytokine production GO:0001819 167 0.053
response to transforming growth factor beta GO:0071559 94 0.053
regulation of hormone levels GO:0010817 125 0.053
protein maturation GO:0051604 233 0.053
regulation of blood vessel size GO:0050880 18 0.053
purine ribonucleotide biosynthetic process GO:0009152 79 0.052
rho protein signal transduction GO:0007266 26 0.052
replacement ossification GO:0036075 1 0.052
regeneration GO:0031099 4 0.051
regulation of exocytosis GO:0017157 46 0.050
regulation of actin cytoskeleton organization GO:0032956 116 0.050
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.050
lung alveolus development GO:0048286 4 0.050
positive regulation of immune response GO:0050778 159 0.049
ameboidal type cell migration GO:0001667 135 0.049
cell activation GO:0001775 213 0.049
positive regulation of proteolysis GO:0045862 142 0.049
regulation of endothelial cell apoptotic process GO:2000351 24 0.049
calcium ion homeostasis GO:0055074 122 0.048
humoral immune response GO:0006959 49 0.048
positive regulation of catabolic process GO:0009896 310 0.048
axon development GO:0061564 34 0.048
endocytosis GO:0006897 159 0.048
Human Mouse
cellular carbohydrate metabolic process GO:0044262 84 0.048
immune response GO:0006955 307 0.047
regulation of cellular amino acid metabolic process GO:0006521 6 0.047
negative regulation of growth GO:0045926 97 0.047
purine containing compound biosynthetic process GO:0072522 88 0.047
cytokine secretion GO:0050663 64 0.047
regulation of protein processing GO:0070613 150 0.047
organic acid transport GO:0015849 65 0.047
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.047
positive regulation of rho protein signal transduction GO:0035025 4 0.047
gastrulation GO:0007369 51 0.047
blood vessel morphogenesis GO:0048514 162 0.046
Human Mouse
blood circulation GO:0008015 113 0.046
Human
monocarboxylic acid metabolic process GO:0032787 185 0.045
negative regulation of complement activation lectin pathway GO:0001869 2 0.045
tube morphogenesis GO:0035239 95 0.045
neuromuscular junction development GO:0007528 3 0.045
regulation of peptidase activity GO:0052547 180 0.045
positive regulation of defense response GO:0031349 87 0.044
negative regulation of phosphorylation GO:0042326 174 0.044
Human
multicellular organismal homeostasis GO:0048871 67 0.043
collateral sprouting GO:0048668 2 0.042
positive regulation of cellular amine metabolic process GO:0033240 7 0.041
neuron remodeling GO:0016322 2 0.041
cognition GO:0050890 43 0.041
negative regulation of cell growth GO:0030308 83 0.040
response to oxygen containing compound GO:1901700 369 0.040
Human
innate immune response activating signal transduction GO:0002758 48 0.040
memory GO:0007613 3 0.040
neurotransmitter gated ion channel clustering GO:0072578 1 0.040
endothelial cell migration GO:0043542 86 0.040
negative regulation of response to wounding GO:1903035 47 0.040
regulation of lipoprotein lipase activity GO:0051004 12 0.039
organonitrogen compound biosynthetic process GO:1901566 200 0.039
Human
organic anion transport GO:0015711 103 0.039
purine nucleotide biosynthetic process GO:0006164 84 0.039
epithelial cell proliferation GO:0050673 128 0.039
collagen catabolic process GO:0030574 10 0.038
positive regulation of cell cycle process GO:0090068 106 0.038
Human
single organism cellular localization GO:1902580 332 0.038
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.038
osteoblast differentiation GO:0001649 92 0.038
Human
sleep GO:0030431 2 0.038
endochondral bone morphogenesis GO:0060350 3 0.037
positive regulation of protein phosphorylation GO:0001934 313 0.037
Human
negative regulation of protein phosphorylation GO:0001933 140 0.037
Human
reactive oxygen species metabolic process GO:0072593 75 0.037
long term memory GO:0007616 2 0.037
tissue morphogenesis GO:0048729 96 0.037
Human
regulation of phospholipase activity GO:0010517 26 0.037
Mouse
multicellular organismal response to stress GO:0033555 1 0.036
regulation of immune response GO:0050776 201 0.036
positive regulation of fibroblast migration GO:0010763 3 0.036
positive regulation of hydrolase activity GO:0051345 331 0.036
cellular response to oxidative stress GO:0034599 85 0.035
cell adhesion molecule production GO:0060352 3 0.035
glycerolipid biosynthetic process GO:0045017 51 0.035
protein activation cascade GO:0072376 22 0.035
cellular cation homeostasis GO:0030003 163 0.035
response to hormone GO:0009725 175 0.034
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.034
Human
positive regulation of lipid metabolic process GO:0045834 50 0.034
motor neuron axon guidance GO:0008045 2 0.034
regulation of erk1 and erk2 cascade GO:0070372 99 0.034
regulation of binding GO:0051098 111 0.034
embryonic morphogenesis GO:0048598 85 0.033
positive regulation of cell substrate adhesion GO:0010811 37 0.033
endothelial cell apoptotic process GO:0072577 26 0.033
positive regulation of cellular component biogenesis GO:0044089 158 0.033
vascular process in circulatory system GO:0003018 29 0.033
cellular macromolecular complex assembly GO:0034622 324 0.033
positive regulation of innate immune response GO:0045089 79 0.033
cerebral cortex cell migration GO:0021795 3 0.033
integrin mediated signaling pathway GO:0007229 32 0.033
protein localization to plasma membrane GO:0072659 93 0.033
establishment of protein localization to plasma membrane GO:0090002 68 0.033
regulation of cell morphogenesis GO:0022604 153 0.032
positive regulation of endocytosis GO:0045807 42 0.032
interleukin 8 production GO:0032637 51 0.032
embryo development GO:0009790 123 0.032
Human
response to steroid hormone GO:0048545 80 0.032
sterol metabolic process GO:0016125 28 0.032
Mouse
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.032
negative regulation of phospholipase activity GO:0010519 3 0.032
pattern recognition receptor signaling pathway GO:0002221 48 0.032
nucleoside monophosphate metabolic process GO:0009123 191 0.031
actin filament based process GO:0030029 224 0.031
Mouse
negative regulation of intracellular signal transduction GO:1902532 183 0.031
regulation of mapk cascade GO:0043408 262 0.031
Human
immune response regulating signaling pathway GO:0002764 97 0.031
negative regulation of peptidase activity GO:0010466 91 0.031
response to other organism GO:0051707 261 0.030
regulation of ras protein signal transduction GO:0046578 155 0.030
mitotic cell cycle process GO:1903047 286 0.030
Human
lipid transport GO:0006869 90 0.030
Mouse
negative regulation of cell motility GO:2000146 104 0.030
Mouse
apoptotic signaling pathway GO:0097190 268 0.030
neuron projection morphogenesis GO:0048812 50 0.030
alcohol metabolic process GO:0006066 114 0.029
Mouse
positive regulation of angiogenesis GO:0045766 51 0.029
negative regulation of organelle organization GO:0010639 126 0.029
epithelium migration GO:0090132 119 0.029
peptidyl tyrosine modification GO:0018212 170 0.029
Human
positive regulation of heterotypic cell cell adhesion GO:0034116 8 0.029
regulation of receptor activity GO:0010469 47 0.029
Human
regulation of protein kinase activity GO:0045859 289 0.029
Human
cholesterol transport GO:0030301 39 0.029
Mouse
regulation of translation GO:0006417 89 0.028
developmental growth involved in morphogenesis GO:0060560 23 0.028
tissue migration GO:0090130 119 0.028
dendritic spine maintenance GO:0097062 1 0.028
multicellular organismal metabolic process GO:0044236 34 0.028
negative regulation of catabolic process GO:0009895 104 0.028
digestive tract morphogenesis GO:0048546 56 0.028
endomembrane system organization GO:0010256 196 0.028
plasminogen activation GO:0031639 11 0.028
positive regulation of actin filament bundle assembly GO:0032233 25 0.028
platelet aggregation GO:0070527 32 0.028
cell morphogenesis involved in differentiation GO:0000904 144 0.028
Human
nucleotide biosynthetic process GO:0009165 109 0.027
metal ion homeostasis GO:0055065 169 0.027
positive regulation of organelle organization GO:0010638 195 0.027
Human
stress fiber assembly GO:0043149 40 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.027
tissue regeneration GO:0042246 3 0.026
purine ribonucleoside metabolic process GO:0046128 437 0.026
regulation of epithelial cell migration GO:0010632 93 0.026
growth of symbiont in host GO:0044117 1 0.026
acylglycerol homeostasis GO:0055090 14 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.026
ras protein signal transduction GO:0007265 73 0.026
purine ribonucleoside catabolic process GO:0046130 398 0.025
positive regulation of cytokine secretion GO:0050715 42 0.025
positive regulation of exocytosis GO:0045921 35 0.025
ribonucleoside monophosphate metabolic process GO:0009161 187 0.025
negative regulation of protein modification process GO:0031400 200 0.025
Human
negative regulation of apoptotic process GO:0043066 316 0.025
Human
nucleoside catabolic process GO:0009164 408 0.025
regulation of cell projection organization GO:0031344 107 0.025
regulation of synaptic plasticity GO:0048167 3 0.025
spinal cord development GO:0021510 4 0.025
ribonucleoside catabolic process GO:0042454 406 0.025
calcium ion transmembrane transport GO:0070588 76 0.025
response to oxygen levels GO:0070482 100 0.024
response to peptide GO:1901652 65 0.024
regulation of blood coagulation GO:0030193 42 0.024
ion transmembrane transport GO:0034220 338 0.024
Human
digestive system development GO:0055123 75 0.024
translation GO:0006412 132 0.024
regulation of protein localization to plasma membrane GO:1903076 40 0.024
cellular ion homeostasis GO:0006873 168 0.024
ribonucleotide catabolic process GO:0009261 405 0.024
cell cell signaling GO:0007267 155 0.024
purine nucleoside monophosphate metabolic process GO:0009126 186 0.024
tissue homeostasis GO:0001894 63 0.024
hemostasis GO:0007599 76 0.024
dna replication GO:0006260 116 0.024
cell junction assembly GO:0034329 67 0.024
female gamete generation GO:0007292 2 0.024
anterior posterior axis specification GO:0009948 2 0.024
morphogenesis of an epithelium GO:0002009 60 0.024
epithelium development GO:0060429 227 0.023
bone mineralization GO:0030282 34 0.023
negative regulation of growth of symbiont in host GO:0044130 1 0.023
erbb signaling pathway GO:0038127 44 0.023
Human
negative regulation of protein catabolic process GO:0042177 59 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.023
regulation of macrophage chemotaxis GO:0010758 4 0.023
regulation of plasma lipoprotein particle levels GO:0097006 32 0.023
myeloid leukocyte migration GO:0097529 62 0.023
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.023
regulation of endopeptidase activity GO:0052548 170 0.023
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 15 0.023
cellular protein complex assembly GO:0043623 188 0.023
regulation of dna metabolic process GO:0051052 153 0.023
negative regulation of hemostasis GO:1900047 22 0.023
anatomical structure homeostasis GO:0060249 100 0.023
muscle cell migration GO:0014812 19 0.023
Mouse
cellular response to organic cyclic compound GO:0071407 127 0.023
Human
regulation of viral process GO:0050792 103 0.022
peptide metabolic process GO:0006518 51 0.022
phospholipid homeostasis GO:0055091 6 0.022
regulation of interleukin 8 production GO:0032677 49 0.022
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.022
regulation of innate immune response GO:0045088 97 0.022
embryonic placenta development GO:0001892 1 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.022
blood coagulation GO:0007596 76 0.022
regulation of complement activation lectin pathway GO:0001868 2 0.022
response to external biotic stimulus GO:0043207 261 0.022
aging GO:0007568 66 0.022
positive regulation of growth GO:0045927 58 0.022
divalent inorganic cation transport GO:0072511 158 0.021
Human
mitotic cell cycle phase transition GO:0044772 162 0.021
modulation of growth of symbiont involved in interaction with host GO:0044144 2 0.021
regulation of lipid transport GO:0032368 44 0.021
Mouse
positive regulation of cell differentiation GO:0045597 211 0.021
Human
sterol catabolic process GO:0016127 3 0.021
sterol transport GO:0015918 39 0.021
Mouse
learning GO:0007612 11 0.021
positive regulation of protein kinase activity GO:0045860 190 0.021
Human
associative learning GO:0008306 1 0.021
regulation of nucleotide biosynthetic process GO:0030808 50 0.021
positive regulation of nervous system development GO:0051962 54 0.021
cellular response to nitrogen compound GO:1901699 144 0.021
fatty acid metabolic process GO:0006631 115 0.020
branching involved in salivary gland morphogenesis GO:0060445 1 0.020
protein polymerization GO:0051258 71 0.020
negative regulation of protein activation cascade GO:2000258 7 0.020
hormone transport GO:0009914 68 0.020
cellular metal ion homeostasis GO:0006875 146 0.020
coagulation GO:0050817 78 0.020
cellular calcium ion homeostasis GO:0006874 117 0.020
neuromuscular process controlling balance GO:0050885 7 0.020
chemical homeostasis within a tissue GO:0048875 3 0.020
cell substrate adherens junction assembly GO:0007045 30 0.020

LRP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.416
neurodegenerative disease DOID:1289 102 0.416
nervous system disease DOID:863 431 0.416
Human
disease of metabolism DOID:0014667 295 0.147
inherited metabolic disorder DOID:655 242 0.147
tauopathy DOID:680 16 0.127
acquired metabolic disease DOID:0060158 58 0.102
disease of mental health DOID:150 70 0.091
lysosomal storage disease DOID:3211 47 0.044
lipid storage disease DOID:9455 28 0.031
myopathy DOID:423 104 0.026
congenital muscular dystrophy DOID:0050557 22 0.026
muscular disease DOID:0080000 114 0.026
muscular dystrophy DOID:9884 51 0.026
musculoskeletal system disease DOID:17 223 0.026
Human
muscle tissue disease DOID:66 113 0.026
brain disease DOID:936 73 0.024
cancer DOID:162 167 0.024
disease of cellular proliferation DOID:14566 174 0.024
organ system cancer DOID:0050686 164 0.023
sensory system disease DOID:0050155 203 0.023
Human
eye and adnexa disease DOID:1492 150 0.023
Human
eye disease DOID:5614 149 0.023
Human