|
|
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment
|
GO:0061317 |
3 |
1.000
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.997
|
|
|
|
regulation of heart induction by regulation of canonical wnt signaling pathway
|
GO:0090081 |
1 |
0.986
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.981
|
|
|
|
regulation of heart induction
|
GO:0090381 |
2 |
0.981
|
|
|
|
heart field specification
|
GO:0003128 |
2 |
0.978
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.975
|
|
|
|
dermatome development
|
GO:0061054 |
3 |
0.975
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.974
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.973
|
|
|
|
regulation of dermatome development
|
GO:0061183 |
3 |
0.973
|
|
|
|
wnt signaling pathway calcium modulating pathway
|
GO:0007223 |
2 |
0.961
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.946
|
Mouse |
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.945
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.941
|
|
|
|
mesodermal cell fate specification
|
GO:0007501 |
2 |
0.938
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.938
|
Human Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.914
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.910
|
Mouse |
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.909
|
Mouse |
|
|
heart induction
|
GO:0003129 |
4 |
0.905
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.883
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.856
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
13 |
0.839
|
Mouse |
|
|
receptor internalization
|
GO:0031623 |
43 |
0.833
|
|
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
3 |
0.831
|
Mouse |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.821
|
Human Mouse Fly |
|
|
cardiac muscle cell fate commitment
|
GO:0060923 |
4 |
0.819
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.796
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.787
|
|
|
|
positive regulation of dermatome development
|
GO:0061184 |
3 |
0.787
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.779
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.771
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.770
|
Mouse |
|
|
regulation of receptor internalization
|
GO:0002090 |
15 |
0.770
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.740
|
Human Mouse |
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.719
|
Human |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.712
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.710
|
Human Mouse |
|
|
regulation of organ formation
|
GO:0003156 |
4 |
0.697
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.690
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.687
|
Mouse |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.677
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.662
|
Human |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.657
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.638
|
Mouse |
|
|
gastrulation
|
GO:0007369 |
51 |
0.627
|
Mouse |
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.625
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.622
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.599
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.593
|
|
|
|
positive regulation of cell fate commitment
|
GO:0010455 |
2 |
0.584
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.583
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.571
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.568
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.567
|
Mouse |
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.565
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.559
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
0.553
|
|
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
2 |
0.549
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.549
|
Human Mouse |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.548
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.548
|
Mouse |
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.545
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.545
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.544
|
|
|
|
organ induction
|
GO:0001759 |
4 |
0.532
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.531
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.511
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.502
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
3 |
0.500
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.490
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.488
|
|
|
|
regulation of mesoderm development
|
GO:2000380 |
4 |
0.471
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.458
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.455
|
|
|
|
negative regulation of mesenchymal cell proliferation
|
GO:0072201 |
3 |
0.453
|
|
|
|
regulation of mesodermal cell fate specification
|
GO:0042661 |
2 |
0.453
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.452
|
Human |
|
|
non canonical wnt signaling pathway via mapk cascade
|
GO:0038030 |
4 |
0.447
|
|
|
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.436
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.434
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.434
|
Human |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.429
|
Human Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.427
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.423
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.423
|
Mouse Fly |
|
|
regulation of cardiac muscle cell differentiation
|
GO:2000725 |
7 |
0.420
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.418
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.417
|
Human Mouse |
|
|
negative regulation of cardiac muscle cell differentiation
|
GO:2000726 |
3 |
0.414
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.412
|
|
|
|
negative regulation of gastrulation
|
GO:2000542 |
4 |
0.405
|
|
|
|
regulation of kidney size
|
GO:0035564 |
2 |
0.400
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.399
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.396
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.392
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.386
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.373
|
|
|
|
positive regulation of cell fate specification
|
GO:0042660 |
2 |
0.369
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.368
|
Mouse |
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.367
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.367
|
Human Mouse |
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.367
|
Mouse |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.366
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.362
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.361
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.361
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.361
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.360
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.355
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.349
|
Human Fly |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.348
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.347
|
Human |
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.347
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.345
|
Human Fly |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.345
|
Human |
|
|
regulation of peroxidase activity
|
GO:2000468 |
2 |
0.342
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.340
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.340
|
Mouse |
|
|
digestive tract development
|
GO:0048565 |
75 |
0.340
|
Mouse |
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.338
|
Mouse |
|
|
cell differentiation in spinal cord
|
GO:0021515 |
1 |
0.336
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.336
|
Human |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.328
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.319
|
Human |
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.316
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.315
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.315
|
Human Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.308
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.304
|
Human |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.304
|
Human |
|
|
regulation of cell fate commitment
|
GO:0010453 |
7 |
0.303
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.300
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.297
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
187 |
0.295
|
Human Fly |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.295
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.295
|
Human |
|
|
right ventricular cardiac muscle tissue morphogenesis
|
GO:0003221 |
2 |
0.294
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.290
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.289
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.284
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.284
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.284
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.281
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.280
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.280
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.277
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.276
|
Human |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.275
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.273
|
Rat |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.269
|
Human |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.265
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.264
|
Human Fly |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.263
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.258
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.257
|
Human |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.250
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.248
|
Mouse |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.247
|
Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.243
|
|
|
|
regulation of wnt signaling pathway involved in heart development
|
GO:0003307 |
3 |
0.242
|
Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.241
|
|
|
|
mesoderm formation
|
GO:0001707 |
10 |
0.237
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.237
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.235
|
Human Fly |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.233
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.232
|
Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.230
|
Mouse |
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.230
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.228
|
Mouse |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.226
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.223
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.223
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.222
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
5 |
0.221
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.219
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.218
|
|
|
|
head development
|
GO:0060322 |
108 |
0.217
|
Mouse |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.217
|
Human Mouse |
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.215
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.212
|
Human |
|
|
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation
|
GO:0044338 |
2 |
0.212
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.211
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.209
|
Mouse |
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.209
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.207
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.206
|
Human |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.205
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.205
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.204
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.203
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.202
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.202
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.201
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.200
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.199
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.198
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.196
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.195
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.195
|
Human |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.193
|
Human |
|
|
anion transport
|
GO:0006820 |
161 |
0.192
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.191
|
Mouse |
|
|
canonical wnt signaling pathway involved in osteoblast differentiation
|
GO:0044339 |
2 |
0.191
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.191
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.189
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.186
|
Mouse |
|
|
cardiac cell fate commitment
|
GO:0060911 |
7 |
0.186
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.186
|
Mouse |
|
|
limbic system development
|
GO:0021761 |
3 |
0.184
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.184
|
|
|
|
negative regulation of cardioblast differentiation
|
GO:0051892 |
2 |
0.184
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.182
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.182
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.182
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.181
|
Human Mouse |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.181
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.179
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
10 |
0.179
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.178
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.177
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.177
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.176
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.176
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.176
|
Human |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.175
|
Rat |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.174
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.173
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.172
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.172
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.171
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.171
|
Human Mouse |
|
|
negative regulation of axon guidance
|
GO:1902668 |
1 |
0.166
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.166
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.166
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.164
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.162
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.162
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.162
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.161
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.159
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.159
|
Human |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.159
|
|
|
|
wnt signaling pathway involved in heart development
|
GO:0003306 |
5 |
0.159
|
Mouse |
|
|
regulation of gastrulation
|
GO:0010470 |
12 |
0.159
|
|
|
|
system process
|
GO:0003008 |
349 |
0.159
|
Human Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.158
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.158
|
Human |
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.158
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.157
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.157
|
|
|
|
axon extension
|
GO:0048675 |
13 |
0.157
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.155
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.154
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.154
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.154
|
|
|
|
regulation of synaptic vesicle endocytosis
|
GO:1900242 |
1 |
0.153
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
5 |
0.152
|
Mouse |
|
|
positive regulation of aldosterone biosynthetic process
|
GO:0032349 |
2 |
0.151
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.151
|
Human |
|
|
ossification
|
GO:0001503 |
121 |
0.151
|
Human Mouse |
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.151
|
Mouse |
|
|
stem cell division
|
GO:0017145 |
2 |
0.150
|
Mouse |
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.150
|
|
|
|
cell proliferation in forebrain
|
GO:0021846 |
1 |
0.149
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.148
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.148
|
Human Fly |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.148
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.147
|
Mouse |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.146
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.146
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.146
|
Mouse |
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.145
|
Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.144
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.144
|
|
|
|
axon extension involved in axon guidance
|
GO:0048846 |
5 |
0.144
|
|
|
|
negative regulation of axon extension
|
GO:0030517 |
2 |
0.143
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.143
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.142
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.142
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.141
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.141
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.140
|
|
|
|
cardioblast cell fate commitment
|
GO:0042684 |
1 |
0.139
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.139
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.138
|
Mouse |
|
|
immune system development
|
GO:0002520 |
195 |
0.137
|
Human |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.137
|
|
|
|
regulation of dopamine receptor signaling pathway
|
GO:0060159 |
3 |
0.136
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.136
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.134
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.134
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.134
|
|
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
4 |
0.133
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.133
|
|
|
|
cellular response to ammonium ion
|
GO:0071242 |
4 |
0.133
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.133
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.132
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.132
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.131
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.131
|
Human |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.131
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
5 |
0.130
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.130
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.130
|
Rat |
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.129
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.128
|
Mouse |
|
|
positive regulation of collateral sprouting
|
GO:0048672 |
2 |
0.128
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.127
|
Mouse |
|
|
growth
|
GO:0040007 |
202 |
0.127
|
Mouse |
|
|
retina vasculature morphogenesis in camera type eye
|
GO:0061299 |
3 |
0.126
|
Human |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.126
|
|
|
|
hair cycle
|
GO:0042633 |
28 |
0.125
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.125
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.124
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.123
|
Human |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.122
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.120
|
|
|
|
negative regulation of pathway restricted smad protein phosphorylation
|
GO:0060394 |
11 |
0.119
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.119
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.119
|
Human |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.116
|
Mouse |
|
|
positive regulation of epithelial cell proliferation involved in wound healing
|
GO:0060054 |
3 |
0.115
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.115
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.115
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.114
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.114
|
Mouse |
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.113
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.113
|
|
|
|
telencephalon development
|
GO:0021537 |
17 |
0.112
|
Mouse |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.112
|
Human |
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.111
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.111
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.111
|
|
|
|
canonical wnt signaling pathway involved in regulation of cell proliferation
|
GO:0044340 |
2 |
0.111
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
247 |
0.111
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.111
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.111
|
|
|
|
regulation of synaptic vesicle recycling
|
GO:1903421 |
1 |
0.110
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.110
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.110
|
|
|
|
non canonical wnt signaling pathway via jnk cascade
|
GO:0038031 |
3 |
0.109
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.109
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.108
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.107
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.107
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.106
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.106
|
|
|
|
positive regulation of steroid hormone biosynthetic process
|
GO:0090031 |
2 |
0.105
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.105
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.105
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.105
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.105
|
|
|
|
regulation of endodermal cell fate specification
|
GO:0042663 |
1 |
0.105
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.104
|
Mouse |
|
|
cardiac cell fate specification
|
GO:0060912 |
1 |
0.104
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.104
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.104
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.104
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.104
|
Human |
|
|
behavior
|
GO:0007610 |
112 |
0.103
|
Fly |
|
|
regulation of sodium dependent phosphate transport
|
GO:2000118 |
2 |
0.103
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.103
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.103
|
|
|
|
tangential migration from the subventricular zone to the olfactory bulb
|
GO:0022028 |
3 |
0.102
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.102
|
Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.102
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.102
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.102
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.101
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.101
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.101
|
|
|
|
cardioblast cell fate specification
|
GO:0042685 |
1 |
0.101
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.101
|
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.101
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.100
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.099
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.099
|
Human |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.099
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.099
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.098
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.098
|
|
|
|
cell fate specification
|
GO:0001708 |
8 |
0.098
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.097
|
Mouse |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.097
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.097
|
Mouse |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.097
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.097
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.096
|
|
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.096
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.096
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.095
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.095
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.095
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.095
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.094
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.094
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.093
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.093
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.092
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.092
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.092
|
Human |
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.091
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.091
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.091
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.090
|
Human |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.089
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.089
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
24 |
0.089
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.088
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.088
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
15 |
0.088
|
Human Mouse |
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.088
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.088
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.088
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.087
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.087
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.087
|
|
|
|
positive regulation of mineralocorticoid secretion
|
GO:2000857 |
1 |
0.086
|
|
|
|
negative regulation of muscle organ development
|
GO:0048635 |
12 |
0.086
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.086
|
Human |
|
|
regulation of cardioblast cell fate specification
|
GO:0042686 |
1 |
0.085
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.085
|
Mouse |
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
3 |
0.084
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.083
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.083
|
Mouse |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.083
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.083
|
Human |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.083
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.083
|
|
|
|
negative regulation of cardioblast cell fate specification
|
GO:0009997 |
1 |
0.082
|
|
|
|
negative regulation of mesodermal cell fate specification
|
GO:0042662 |
1 |
0.082
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.082
|
Mouse |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.082
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.082
|
|
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.082
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.082
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.082
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.081
|
Mouse |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.080
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.080
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.079
|
Rat |
|
|
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901030 |
3 |
0.079
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.079
|
Human |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.078
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.078
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.078
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.078
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.077
|
Mouse |
|
|
negative regulation of cell projection organization
|
GO:0031345 |
22 |
0.076
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.076
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.076
|
Mouse |
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.076
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.076
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.076
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.076
|
|
|
|
regulation of cell maturation
|
GO:1903429 |
3 |
0.075
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.074
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.074
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.074
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.074
|
Mouse |
|
|
nuclear import
|
GO:0051170 |
106 |
0.073
|
Human |
|
|
negative regulation of muscle cell differentiation
|
GO:0051148 |
17 |
0.073
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.072
|
Human |
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.072
|
Human |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.072
|
|
|
|
positive regulation of receptor internalization
|
GO:0002092 |
12 |
0.072
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.072
|
|
|
|
developmental induction
|
GO:0031128 |
5 |
0.072
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.071
|
|
|
|
positive regulation of cytokine secretion involved in immune response
|
GO:0002741 |
2 |
0.070
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.070
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.069
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.069
|
|
|
|
rostrocaudal neural tube patterning
|
GO:0021903 |
1 |
0.069
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.069
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.069
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.068
|
Mouse |
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.068
|
Human |
|
|
molting cycle process
|
GO:0022404 |
12 |
0.068
|
|
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.067
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.067
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.067
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.067
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.067
|
Mouse |
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.067
|
Human Mouse |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.067
|
Rat |
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.066
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.066
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.066
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.066
|
Human |
|
|
endoderm formation
|
GO:0001706 |
33 |
0.065
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.065
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.065
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.065
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.065
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.065
|
Mouse |
