Homo sapiens

72 known processes

LRSAM1

leucine rich repeat and sterile alpha motif containing 1

(Aliases: TAL,FLJ31641,RIFLE)

LRSAM1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
viral budding GO:0046755 9 0.538
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.327
cytoskeleton dependent cytokinesis GO:0061640 22 0.315
protein modification by small protein conjugation GO:0032446 342 0.289
regulation of cell cycle GO:0051726 393 0.282
multivesicular body organization GO:0036257 2 0.255
mitochondrial respiratory chain complex assembly GO:0033108 23 0.241
growth of symbiont in host GO:0044117 1 0.239
axon cargo transport GO:0008088 2 0.239
growth GO:0040007 202 0.225
post embryonic development GO:0009791 2 0.210
i kappab kinase nf kappab signaling GO:0007249 166 0.205
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.193
cellular macromolecule catabolic process GO:0044265 380 0.190
multi organism organelle organization GO:1902590 9 0.183
cell growth GO:0016049 160 0.168
negative regulation of growth of symbiont involved in interaction with host GO:0044146 2 0.165
multi organism cellular process GO:0044764 156 0.156
intracellular protein transport GO:0006886 270 0.155
protein glycosylation GO:0006486 62 0.151
protein ubiquitination GO:0016567 314 0.147
viral life cycle GO:0019058 132 0.143
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.143
interspecies interaction between organisms GO:0044419 156 0.129
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.120
protein polyubiquitination GO:0000209 110 0.118
protein localization to synapse GO:0035418 2 0.118
ubiquitin dependent protein catabolic process GO:0006511 206 0.117
bleb assembly GO:0032060 6 0.116
vesicle mediated transport GO:0016192 371 0.114
cytoskeleton dependent intracellular transport GO:0030705 21 0.114
cellular protein catabolic process GO:0044257 261 0.113
viral process GO:0016032 146 0.113
glycosylation GO:0070085 71 0.113
multivesicular body assembly GO:0036258 1 0.108
negative regulation of growth of symbiont in host GO:0044130 1 0.107
modification dependent macromolecule catabolic process GO:0043632 212 0.104
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.094
negative regulation of cell proliferation GO:0008285 228 0.088
cell morphogenesis GO:0000902 296 0.086
cellular component morphogenesis GO:0032989 314 0.085
cytochrome complex assembly GO:0017004 13 0.084
single organism cellular localization GO:1902580 332 0.084
nuclear division GO:0000280 128 0.084
mitochondrion organization GO:0007005 156 0.083
modification dependent protein catabolic process GO:0019941 209 0.082
cellular protein complex assembly GO:0043623 188 0.077
protein catabolic process GO:0030163 325 0.077
protein autoubiquitination GO:0051865 37 0.074
multi organism membrane organization GO:0044803 12 0.072
macromolecule glycosylation GO:0043413 63 0.072
carbohydrate metabolic process GO:0005975 207 0.070
viral gene expression GO:0019080 35 0.069
modulation of growth of symbiont involved in interaction with host GO:0044144 2 0.068
negative regulation of multi organism process GO:0043901 92 0.066
glycoprotein metabolic process GO:0009100 110 0.066
glycoprotein biosynthetic process GO:0009101 91 0.062
cell division GO:0051301 168 0.062
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.061
organelle fission GO:0048285 149 0.061
ribonucleoprotein complex disassembly GO:0032988 7 0.060
regulation of multi organism process GO:0043900 157 0.059
neuron differentiation GO:0030182 138 0.059
organelle disassembly GO:1903008 9 0.058
carbohydrate derivative biosynthetic process GO:1901137 207 0.057
female gamete generation GO:0007292 2 0.057
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 10 0.055
regulation of establishment of protein localization GO:0070201 242 0.053
viral entry into host cell GO:0046718 24 0.052
growth of symbiont involved in interaction with host GO:0044116 2 0.052
cell part morphogenesis GO:0032990 137 0.052
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.051
morphogenesis of embryonic epithelium GO:0016331 4 0.050
multi organism membrane budding GO:1902592 9 0.049
oogenesis GO:0048477 2 0.049
membrane organization GO:0061024 292 0.049
positive regulation of cellular component biogenesis GO:0044089 158 0.047
single organism carbohydrate metabolic process GO:0044723 193 0.047
protein n linked glycosylation GO:0006487 23 0.046
regulation of transferase activity GO:0051338 355 0.046
innate immune response GO:0045087 178 0.044
ribonucleoprotein complex subunit organization GO:0071826 81 0.044
negative regulation of epithelial cell migration GO:0010633 38 0.043
neuron projection development GO:0031175 106 0.043
negative regulation of multicellular organismal process GO:0051241 317 0.043
regulation of cytoskeleton organization GO:0051493 177 0.043
developmental growth involved in morphogenesis GO:0060560 23 0.042
regulation of growth GO:0040008 165 0.042
macromolecular complex disassembly GO:0032984 60 0.042
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.042
cellular component disassembly GO:0022411 92 0.042
oocyte differentiation GO:0009994 2 0.041
endomembrane system organization GO:0010256 196 0.041
receptor catabolic process GO:0032801 11 0.041
mitotic nuclear division GO:0007067 119 0.041
cell projection organization GO:0030030 252 0.041
negative regulation of phosphate metabolic process GO:0045936 267 0.040
nervous system development GO:0007399 293 0.040
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.040
multi organism metabolic process GO:0044033 41 0.039
entry into host GO:0044409 25 0.038
positive regulation of transport GO:0051050 336 0.038
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.038
secretion by cell GO:0032940 226 0.038
movement in environment of other organism involved in symbiotic interaction GO:0052192 25 0.038
positive regulation of exocytosis GO:0045921 35 0.037
protein monoubiquitination GO:0006513 39 0.037
synaptic vesicle transport GO:0048489 5 0.037
positive regulation of exosomal secretion GO:1903543 12 0.036
regulation of adherens junction organization GO:1903391 21 0.035
axis elongation GO:0003401 4 0.035
cell projection morphogenesis GO:0048858 129 0.035
apoptotic signaling pathway GO:0097190 268 0.035
myoblast migration GO:0051451 1 0.034
mitotic cell cycle GO:0000278 326 0.034
synaptic vesicle localization GO:0097479 5 0.033
negative regulation of viral process GO:0048525 66 0.033
growth involved in symbiotic interaction GO:0044110 2 0.032
early endosome to late endosome transport GO:0045022 21 0.032
cell cell signaling GO:0007267 155 0.032
cellular response to dna damage stimulus GO:0006974 379 0.031
protein modification by small protein removal GO:0070646 92 0.031
morphogenesis of a polarized epithelium GO:0001738 3 0.030
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.030
actin filament based process GO:0030029 224 0.030
regulation of vesicle mediated transport GO:0060627 130 0.030
protein k48 linked ubiquitination GO:0070936 38 0.030
determination of adult lifespan GO:0008340 2 0.030
endosomal transport GO:0016197 129 0.030
neuromuscular junction development GO:0007528 3 0.030
single organism membrane organization GO:0044802 268 0.030
response to external biotic stimulus GO:0043207 261 0.030
microtubule based movement GO:0007018 32 0.030
cell morphogenesis involved in differentiation GO:0000904 144 0.030
neurogenesis GO:0022008 169 0.029
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.029
proteasomal protein catabolic process GO:0010498 176 0.029
regulation of exosomal secretion GO:1903541 12 0.029
mitochondrial respiratory chain complex iii assembly GO:0034551 4 0.028
cell development GO:0048468 328 0.028
multicellular organismal aging GO:0010259 3 0.028
developmental cell growth GO:0048588 18 0.028
positive regulation of cellular component organization GO:0051130 376 0.028
neuron development GO:0048666 113 0.028
regulation of proteolysis GO:0030162 293 0.028
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.028
entry into host cell GO:0030260 25 0.028
entry into other organism involved in symbiotic interaction GO:0051828 25 0.028
negative regulation of phosphorus metabolic process GO:0010563 267 0.027
cardiovascular system development GO:0072358 262 0.027
regulation of cell growth GO:0001558 135 0.026
regulation of cell cycle process GO:0010564 266 0.026
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
regulation of protein ubiquitination GO:0031396 95 0.026
generation of neurons GO:0048699 152 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
actin mediated cell contraction GO:0070252 12 0.025
regulation of kinase activity GO:0043549 314 0.025
epithelium development GO:0060429 227 0.025
regulation of secretion GO:0051046 194 0.025
regulation of viral transcription GO:0046782 34 0.024
movement in host environment GO:0052126 25 0.024
maintenance of location GO:0051235 112 0.024
regulation of protein localization GO:0032880 296 0.024
mitochondrial respiratory chain complex iii biogenesis GO:0097033 4 0.024
spindle elongation GO:0051231 4 0.024
regulation of growth of symbiont in host GO:0044126 1 0.024
protein deubiquitination GO:0016579 79 0.024
cell fate determination GO:0001709 3 0.023
regulation of actin cytoskeleton organization GO:0032956 116 0.023
establishment of planar polarity GO:0001736 3 0.023
interaction with host GO:0051701 42 0.023
regulation of cytokine production GO:0001817 232 0.023
cell cycle arrest GO:0007050 71 0.023
cell type specific apoptotic process GO:0097285 125 0.022
neuron projection extension GO:1990138 14 0.022
positive regulation of phosphorylation GO:0042327 394 0.022
microtubule based transport GO:0010970 21 0.022
regulation of viral process GO:0050792 103 0.022
spermatid differentiation GO:0048515 4 0.022
negative regulation of protein metabolic process GO:0051248 391 0.022
secretion GO:0046903 254 0.021
regulation of viral release from host cell GO:1902186 20 0.021
dephosphorylation GO:0016311 209 0.021
mitotic spindle elongation GO:0000022 4 0.021
establishment of synaptic vesicle localization GO:0097480 5 0.021
regulation of intracellular transport GO:0032386 195 0.020
epithelial cell differentiation GO:0030855 141 0.020
organelle assembly GO:0070925 176 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.019
coagulation GO:0050817 78 0.019
regulation of dephosphorylation GO:0035303 96 0.019
negative regulation of viral transcription GO:0032897 23 0.019
negative regulation of locomotion GO:0040013 118 0.019
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.019
amine metabolic process GO:0009308 44 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
segmentation GO:0035282 4 0.018
microtubule cytoskeleton organization GO:0000226 176 0.018
regulation of viral entry into host cell GO:0046596 17 0.018
organ morphogenesis GO:0009887 147 0.018
synaptic transmission GO:0007268 61 0.018
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.018
viral transcription GO:0019083 35 0.018
positive regulation of viral entry into host cell GO:0046598 3 0.017
neurological system process GO:0050877 163 0.017
response to oxygen containing compound GO:1901700 369 0.017
cellular lipid metabolic process GO:0044255 303 0.017
regulation of protein catabolic process GO:0042176 155 0.017
regulation of meiotic cell cycle GO:0051445 4 0.017
jak stat cascade GO:0007259 46 0.017
cytokine production GO:0001816 247 0.017
mitotic cell cycle process GO:1903047 286 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
vesicle localization GO:0051648 26 0.017
epithelial cell migration GO:0010631 119 0.017
memory GO:0007613 3 0.017
axon development GO:0061564 34 0.017
membrane budding GO:0006900 28 0.016
endosome to lysosome transport via multivesicular body sorting pathway GO:0032510 2 0.016
regulation of interleukin 2 secretion GO:1900040 2 0.016
positive regulation of intracellular transport GO:0032388 104 0.016
compound eye development GO:0048749 1 0.016
protein localization to membrane GO:0072657 160 0.016
positive regulation of transferase activity GO:0051347 227 0.016
response to other organism GO:0051707 261 0.016
exosomal secretion GO:1990182 15 0.016
establishment of organelle localization GO:0051656 59 0.016
response to biotic stimulus GO:0009607 276 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
negative regulation of protein transport GO:0051224 75 0.016
regulation of jak stat cascade GO:0046425 44 0.016
viral release from host cell GO:0019076 21 0.016
regulation of secretion by cell GO:1903530 177 0.016
axon extension GO:0048675 13 0.015
regulation of neuron differentiation GO:0045664 70 0.015
positive regulation of early endosome to late endosome transport GO:2000643 3 0.015
protein maturation GO:0051604 233 0.015
protein localization to organelle GO:0033365 280 0.015
lipid metabolic process GO:0006629 381 0.015
regulation of locomotion GO:0040012 329 0.015
anterior posterior axis specification GO:0009948 2 0.015
regulation of protein kinase activity GO:0045859 289 0.015
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.015
regeneration GO:0031099 4 0.015
negative regulation of protein modification process GO:0031400 200 0.015
neuron projection morphogenesis GO:0048812 50 0.015
keratinocyte differentiation GO:0030216 36 0.015
regulation of exocytosis GO:0017157 46 0.015
circulatory system development GO:0072359 262 0.015
regulation of synaptic plasticity GO:0048167 3 0.015
hindbrain development GO:0030902 3 0.015
protein processing GO:0016485 226 0.015
positive regulation of cell death GO:0010942 263 0.015
cellular chemical homeostasis GO:0055082 180 0.014
intrinsic apoptotic signaling pathway GO:0097193 127 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
establishment of tissue polarity GO:0007164 3 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
regulation of protein maturation GO:1903317 150 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
peripheral nervous system development GO:0007422 2 0.014
positive regulation of protein ubiquitination GO:0031398 53 0.014
histone modification GO:0016570 251 0.014
inner ear morphogenesis GO:0042472 4 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
developmental growth GO:0048589 48 0.014
negative regulation of cellular component movement GO:0051271 106 0.014
regulation of actin filament based process GO:0032970 141 0.014
metencephalon development GO:0022037 2 0.014
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.014
regulation of neuron death GO:1901214 56 0.013
epidermis development GO:0008544 59 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
regulation of meiosis GO:0040020 3 0.013
receptor metabolic process GO:0043112 81 0.013
positive regulation of developmental process GO:0051094 314 0.013
tissue regeneration GO:0042246 3 0.013
epidermal cell differentiation GO:0009913 45 0.013
mitotic sister chromatid segregation GO:0000070 53 0.013
negative regulation of cell migration GO:0030336 102 0.013
oocyte development GO:0048599 1 0.013
regulation of cellular ketone metabolic process GO:0010565 50 0.013
limbic system development GO:0021761 3 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
exocytosis GO:0006887 71 0.013
dna repair GO:0006281 198 0.013
negative regulation of cell cycle GO:0045786 193 0.013
regulation of vasculature development GO:1901342 97 0.013
cytoplasmic transport GO:0016482 379 0.013
regulation of cell motility GO:2000145 299 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
negative regulation of cytokine production GO:0001818 82 0.013
negative regulation of growth GO:0045926 97 0.013
defense response GO:0006952 315 0.013
protein dephosphorylation GO:0006470 81 0.013
ionotropic glutamate receptor signaling pathway GO:0035235 16 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
protein secretion GO:0009306 98 0.012
response to bacterium GO:0009617 144 0.012
chromatin modification GO:0016568 298 0.012
regulation of cell adhesion GO:0030155 166 0.012
intracellular receptor signaling pathway GO:0030522 104 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
ion transmembrane transport GO:0034220 338 0.012
tube closure GO:0060606 3 0.012
stem cell division GO:0017145 2 0.012
regulation of actin filament bundle assembly GO:0032231 36 0.012
neural tube formation GO:0001841 3 0.012
actin filament organization GO:0007015 128 0.012
metal ion transport GO:0030001 272 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
transmembrane transport GO:0055085 399 0.012
positive regulation of cytokine production GO:0001819 167 0.011
glycosyl compound catabolic process GO:1901658 413 0.011
microtubule based process GO:0007017 210 0.011
regulation of protein processing GO:0070613 150 0.011
maintenance of protein location GO:0045185 57 0.011
blood coagulation GO:0007596 76 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
regulation of protein stability GO:0031647 87 0.011
cellular amino acid metabolic process GO:0006520 116 0.011
axonogenesis GO:0007409 31 0.011
negative regulation of programmed cell death GO:0043069 321 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
adult locomotory behavior GO:0008344 1 0.011
positive regulation of secretion by cell GO:1903532 108 0.011
meiosis i GO:0007127 4 0.011
regulation of neuron projection development GO:0010975 57 0.011
negative regulation of dephosphorylation GO:0035305 63 0.011
negative regulation of cellular component organization GO:0051129 235 0.011
regulation of mapk cascade GO:0043408 262 0.011
alpha amino acid metabolic process GO:1901605 72 0.011
angiogenesis GO:0001525 147 0.011
endocytosis GO:0006897 159 0.011
non canonical wnt signaling pathway GO:0035567 14 0.011
cation transport GO:0006812 331 0.011
cellular homeostasis GO:0019725 196 0.011
retrograde transport endosome to golgi GO:0042147 45 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
centrosome organization GO:0051297 58 0.011
cellular cation homeostasis GO:0030003 163 0.011
myoblast fusion GO:0007520 1 0.011
regulation of neurogenesis GO:0050767 82 0.011
regulation of cellular component movement GO:0051270 334 0.011
regulation of protein transport GO:0051223 213 0.011
protein k63 linked ubiquitination GO:0070534 31 0.011
negative regulation of developmental process GO:0051093 247 0.011
negative regulation of protein maturation GO:1903318 142 0.011
forebrain generation of neurons GO:0021872 3 0.011
somitogenesis GO:0001756 2 0.010
ribonucleotide catabolic process GO:0009261 405 0.010
reactive nitrogen species metabolic process GO:2001057 3 0.010
organophosphate biosynthetic process GO:0090407 163 0.010
regulation of cellular protein catabolic process GO:1903362 96 0.010
positive regulation of organelle organization GO:0010638 195 0.010
peptidyl tyrosine dephosphorylation GO:0035335 36 0.010
negative regulation of protein deubiquitination GO:0090086 3 0.010
regulation of metal ion transport GO:0010959 120 0.010
regulation of nucleocytoplasmic transport GO:0046822 98 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.010
regulation of cell junction assembly GO:1901888 29 0.010
negative regulation of hydrolase activity GO:0051346 182 0.010
negative regulation of interleukin 2 secretion GO:1900041 2 0.010
negative regulation of blood vessel morphogenesis GO:2000181 41 0.010
primary neural tube formation GO:0014020 3 0.010
regulation of cellular response to stress GO:0080135 244 0.010
blastoderm segmentation GO:0007350 2 0.010

LRSAM1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.113
disease of cellular proliferation DOID:14566 174 0.113
organ system cancer DOID:0050686 164 0.113
musculoskeletal system disease DOID:17 223 0.028
muscle tissue disease DOID:66 113 0.023
muscular disease DOID:0080000 114 0.023
myopathy DOID:423 104 0.023
eye and adnexa disease DOID:1492 150 0.017
nervous system disease DOID:863 431 0.017
sensory system disease DOID:0050155 203 0.017
eye disease DOID:5614 149 0.017
central nervous system disease DOID:331 186 0.016
neurodegenerative disease DOID:1289 102 0.014
cardiovascular system disease DOID:1287 106 0.013
breast cancer DOID:1612 21 0.012
thoracic cancer DOID:5093 21 0.012
disease of metabolism DOID:0014667 295 0.011
gastrointestinal system cancer DOID:3119 52 0.011
retinal disease DOID:5679 118 0.011
neuropathy DOID:870 52 0.010
neuromuscular disease DOID:440 38 0.009
charcot marie tooth disease DOID:10595 33 0.004
charcot marie tooth disease type 2 DOID:0050539 15 0.002