Homo sapiens

329 known processes

MAD2L2

MAD2 mitotic arrest deficient-like 2 (yeast)

(Aliases: REV7,MAD2B)

MAD2L2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.999
monocyte activation GO:0042117 3 0.967
regulation of keratinocyte migration GO:0051547 4 0.941
receptor transactivation GO:0035624 4 0.924
positive regulation of keratinocyte migration GO:0051549 4 0.873
regulation of lymphocyte chemotaxis GO:1901623 12 0.853
mitotic cell cycle GO:0000278 326 0.845
regulation of lymphocyte migration GO:2000401 22 0.822
positive regulation of protein catabolic process GO:0045732 75 0.817
cyclin catabolic process GO:0008054 6 0.816
g protein coupled receptor signaling pathway GO:0007186 207 0.809
regulation of t cell chemotaxis GO:0010819 7 0.789
regulation of cellular amine metabolic process GO:0033238 11 0.752
positive regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle GO:0031659 8 0.743
cellular ketone metabolic process GO:0042180 80 0.730
positive regulation of t cell chemotaxis GO:0010820 7 0.698
cell cycle phase transition GO:0044770 173 0.696
regulation of ligase activity GO:0051340 29 0.656
protein catabolic process GO:0030163 325 0.643
regulation of proteolysis GO:0030162 293 0.620
positive regulation of cellular amine metabolic process GO:0033240 7 0.612
cellular amino acid metabolic process GO:0006520 116 0.593
regulation of cellular amino acid metabolic process GO:0006521 6 0.556
positive regulation of lymphocyte migration GO:2000403 16 0.533
mitotic cell cycle phase transition GO:0044772 162 0.519
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.517
chromosome segregation GO:0007059 114 0.511
regulation of cell cycle GO:0051726 393 0.510
positive regulation of immune system process GO:0002684 283 0.509
mitotic cell cycle process GO:1903047 286 0.502
protein k11 linked ubiquitination GO:0070979 24 0.497
regulation of transferase activity GO:0051338 355 0.494
positive regulation of proteolysis GO:0045862 142 0.483
cellular response to molecule of bacterial origin GO:0071219 62 0.481
amine metabolic process GO:0009308 44 0.479
mitotic sister chromatid segregation GO:0000070 53 0.471
response to decreased oxygen levels GO:0036293 96 0.463
pma inducible membrane protein ectodomain proteolysis GO:0051088 3 0.463
cellular response to endogenous stimulus GO:0071495 336 0.433
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 15 0.432
metaphase anaphase transition of cell cycle GO:0044784 21 0.431
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.431
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.414
regulation of nuclear division GO:0051783 65 0.413
regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle GO:0031657 9 0.411
positive regulation of cell cycle GO:0045787 140 0.410
ubiquitin dependent protein catabolic process GO:0006511 206 0.403
positive regulation of mapk cascade GO:0043410 190 0.391
response to external biotic stimulus GO:0043207 261 0.386
positive regulation of cytokine production GO:0001819 167 0.381
positive regulation of transferase activity GO:0051347 227 0.358
positive regulation of t cell migration GO:2000406 13 0.349
response to oxygen containing compound GO:1901700 369 0.348
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.341
meiotic chromosome segregation GO:0045132 4 0.338
membrane protein ectodomain proteolysis GO:0006509 33 0.335
regulation of leukocyte migration GO:0002685 63 0.331
female gamete generation GO:0007292 2 0.329
regulation of mitosis GO:0007088 63 0.325
regulation of behavior GO:0050795 82 0.318
protein ubiquitination GO:0016567 314 0.318
positive regulation of leukocyte chemotaxis GO:0002690 38 0.312
keratinocyte migration GO:0051546 6 0.306
response to molecule of bacterial origin GO:0002237 82 0.294
positive regulation of ubiquitin protein transferase activity GO:0051443 18 0.291
chemokine production GO:0032602 32 0.288
response to oxygen levels GO:0070482 100 0.285
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.283
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.275
cellular response to oxygen containing compound GO:1901701 276 0.275
response to cytokine GO:0034097 232 0.274
cell division GO:0051301 168 0.272
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.270
oocyte maturation GO:0001556 1 0.266
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.265
regulation of cytokine production GO:0001817 232 0.264
macrophage fusion GO:0034238 1 0.261
regulation of meiotic cell cycle GO:0051445 4 0.250
regulation of epidermal growth factor activated receptor activity GO:0007176 14 0.231
regulation of leukocyte chemotaxis GO:0002688 46 0.228
t cell migration GO:0072678 16 0.227
positive regulation of epidermal growth factor activated receptor activity GO:0045741 8 0.225
positive regulation of kinase activity GO:0033674 204 0.224
response to hypoxia GO:0001666 96 0.223
response to bacterium GO:0009617 144 0.220
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.217
cellular macromolecule catabolic process GO:0044265 380 0.216
regulation of cell cycle process GO:0010564 266 0.215
positive regulation of protein kinase activity GO:0045860 190 0.212
positive regulation of catabolic process GO:0009896 310 0.204
positive regulation of behavior GO:0048520 60 0.203
positive regulation of membrane protein ectodomain proteolysis GO:0051044 13 0.199
t cell chemotaxis GO:0010818 10 0.197
mapk cascade GO:0000165 288 0.195
taxis GO:0042330 157 0.191
regulation of chemokine production GO:0032642 31 0.191
positive regulation of leukocyte migration GO:0002687 46 0.187
leukocyte activation GO:0045321 164 0.185
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.184
positive regulation of cellular catabolic process GO:0031331 284 0.182
positive regulation of ligase activity GO:0051351 19 0.178
regulation of mitotic cell cycle GO:0007346 189 0.177
positive regulation of cellular component organization GO:0051130 376 0.177
response to lipopolysaccharide GO:0032496 70 0.177
response to manganese ion GO:0010042 2 0.176
positive regulation of chemokine production GO:0032722 22 0.170
notch receptor processing GO:0007220 2 0.169
response to biotic stimulus GO:0009607 276 0.168
regulation of t cell migration GO:2000404 14 0.165
cellular response to biotic stimulus GO:0071216 71 0.164
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.158
positive regulation of protein phosphorylation GO:0001934 313 0.156
regulation of protein secretion GO:0050708 86 0.155
protein modification by small protein conjugation GO:0032446 342 0.151
meiosis i GO:0007127 4 0.151
cytokine production GO:0001816 247 0.150
membrane protein proteolysis GO:0033619 38 0.150
epithelium migration GO:0090132 119 0.150
regulation of cell growth GO:0001558 135 0.143
modification dependent protein catabolic process GO:0019941 209 0.141
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.141
lymphocyte migration GO:0072676 28 0.140
positive regulation of cell division GO:0051781 59 0.138
positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 11 0.136
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 2 0.133
response to metal ion GO:0010038 84 0.131
regulation of mitotic cell cycle phase transition GO:1901990 118 0.130
regulation of mapk cascade GO:0043408 262 0.127
positive regulation of protein secretion GO:0050714 60 0.126
regulation of meiosis GO:0040020 3 0.126
leukocyte chemotaxis GO:0030595 76 0.125
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.123
cellular response to lipopolysaccharide GO:0071222 57 0.122
cellular response to growth factor stimulus GO:0071363 197 0.120
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.120
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.116
interleukin 8 production GO:0032637 51 0.116
response to reactive oxygen species GO:0000302 61 0.116
regulation of cell division GO:0051302 116 0.114
positive regulation of mitosis GO:0045840 25 0.114
chromosome separation GO:0051304 23 0.114
regulation of proteasomal protein catabolic process GO:0061136 87 0.113
regulation of receptor activity GO:0010469 47 0.111
positive regulation of locomotion GO:0040017 186 0.110
cell growth GO:0016049 160 0.110
cellular lipid metabolic process GO:0044255 303 0.109
activation of mitotic anaphase promoting complex activity GO:0007092 2 0.109
negative regulation of mitotic anaphase promoting complex activity GO:0060564 4 0.109
negative regulation of cell cycle process GO:0010948 121 0.108
enzyme linked receptor protein signaling pathway GO:0007167 303 0.108
regulation of protein serine threonine kinase activity GO:0071900 179 0.107
cell activation GO:0001775 213 0.105
response to steroid hormone GO:0048545 80 0.104
regulation of cellular response to growth factor stimulus GO:0090287 76 0.104
oocyte differentiation GO:0009994 2 0.102
modification dependent macromolecule catabolic process GO:0043632 212 0.102
oogenesis GO:0048477 2 0.101
syncytium formation by plasma membrane fusion GO:0000768 2 0.100
positive regulation of cell proliferation GO:0008284 301 0.099
regulation of cell cycle phase transition GO:1901987 126 0.099
response to transition metal nanoparticle GO:1990267 29 0.098
organelle fission GO:0048285 149 0.097
negative regulation of protein maturation GO:1903318 142 0.096
response to high density lipoprotein particle GO:0055099 1 0.095
positive regulation of cell adhesion mediated by integrin GO:0033630 9 0.095
nuclear division GO:0000280 128 0.094
chemotaxis GO:0006935 157 0.094
leukocyte migration GO:0050900 107 0.092
regulation of protein localization GO:0032880 296 0.091
positive regulation of secretion GO:0051047 116 0.090
regulation of response to external stimulus GO:0032101 222 0.089
positive regulation of secretion by cell GO:1903532 108 0.088
positive regulation of protein ubiquitination GO:0031398 53 0.087
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.086
protein maturation GO:0051604 233 0.085
cell cycle g1 s phase transition GO:0044843 80 0.085
regulation of interleukin 8 production GO:0032677 49 0.083
regulation of protein maturation GO:1903317 150 0.082
mitotic sister chromatid separation GO:0051306 18 0.081
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.081
cellular response to lipid GO:0071396 127 0.080
regulation of secretion GO:0051046 194 0.080
positive regulation of response to external stimulus GO:0032103 88 0.078
histone modification GO:0016570 251 0.076
cellular response to dna damage stimulus GO:0006974 379 0.076
positive regulation of transport GO:0051050 336 0.076
response to lipid GO:0033993 206 0.075
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.074
regulation of cell differentiation GO:0045595 393 0.074
signal transduction by phosphorylation GO:0023014 297 0.073
protein localization to chromosome GO:0034502 30 0.073
regulation of chromosome segregation GO:0051983 44 0.071
oocyte development GO:0048599 1 0.070
g1 s transition of mitotic cell cycle GO:0000082 78 0.070
regulation of secretion by cell GO:1903530 177 0.069
ameboidal type cell migration GO:0001667 135 0.069
regulation of binding GO:0051098 111 0.068
response to organic cyclic compound GO:0014070 204 0.067
covalent chromatin modification GO:0016569 254 0.067
positive regulation of developmental process GO:0051094 314 0.067
regulation of ubiquitin protein transferase activity GO:0051438 28 0.067
mitotic nuclear division GO:0007067 119 0.067
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.066
growth GO:0040007 202 0.066
single organism cell adhesion GO:0098602 179 0.066
negative regulation of protein metabolic process GO:0051248 391 0.065
activation of anaphase promoting complex activity GO:0051488 6 0.064
wound healing GO:0042060 115 0.063
peptidyl serine phosphorylation GO:0018105 101 0.063
positive regulation of mitotic cell cycle GO:0045931 60 0.063
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.062
negative regulation of cellular catabolic process GO:0031330 83 0.060
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.060
response to growth factor GO:0070848 205 0.059
cellular protein catabolic process GO:0044257 261 0.058
regulation of chemotaxis GO:0050920 74 0.058
negative regulation of cellular protein metabolic process GO:0032269 353 0.057
positive regulation of cell growth GO:0030307 48 0.057
response to tumor necrosis factor GO:0034612 76 0.057
regulation of protein ubiquitination GO:0031396 95 0.056
protein localization to kinetochore GO:0034501 10 0.056
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.056
negative regulation of cell death GO:0060548 345 0.056
positive regulation of chemotaxis GO:0050921 57 0.055
nervous system development GO:0007399 293 0.054
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.054
sister chromatid segregation GO:0000819 54 0.054
negative regulation of catalytic activity GO:0043086 335 0.054
cell cycle checkpoint GO:0000075 117 0.054
lipid metabolic process GO:0006629 381 0.054
myeloid leukocyte activation GO:0002274 34 0.053
positive regulation of chromosome organization GO:2001252 41 0.052
protein polyubiquitination GO:0000209 110 0.052
regulation of protein transport GO:0051223 213 0.052
cell matrix adhesion GO:0007160 85 0.052
positive regulation of cell motility GO:2000147 177 0.052
tissue migration GO:0090130 119 0.051
epiboly involved in wound healing GO:0090505 8 0.051
cellular amine metabolic process GO:0044106 41 0.050
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.050
negative regulation of protein processing GO:0010955 142 0.048
peptidyl tyrosine phosphorylation GO:0018108 170 0.048
oxidation reduction process GO:0055114 396 0.048
exit from mitosis GO:0010458 10 0.048
positive regulation of erbb signaling pathway GO:1901186 11 0.047
protein localization to organelle GO:0033365 280 0.047
mitotic cell cycle checkpoint GO:0007093 68 0.046
response to hydrogen peroxide GO:0042542 40 0.046
regulation of protein catabolic process GO:0042176 155 0.046
response to calcium ion GO:0051592 46 0.045
negative regulation of apoptotic process GO:0043066 316 0.045
negative regulation of cytokine production GO:0001818 82 0.044
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.044
reactive oxygen species metabolic process GO:0072593 75 0.043
negative regulation of programmed cell death GO:0043069 321 0.043
peptidyl serine modification GO:0018209 106 0.043
secretion GO:0046903 254 0.043
maintenance of location GO:0051235 112 0.043
regulation of membrane protein ectodomain proteolysis GO:0051043 17 0.043
response to inorganic substance GO:0010035 127 0.042
positive regulation of cell cycle process GO:0090068 106 0.042
regulation of protein kinase activity GO:0045859 289 0.041
response to transforming growth factor beta GO:0071559 94 0.041
negative regulation of multicellular organismal process GO:0051241 317 0.040
organonitrogen compound biosynthetic process GO:1901566 200 0.040
protein secretion GO:0009306 98 0.040
protein processing GO:0016485 226 0.040
regeneration GO:0031099 4 0.039
organophosphate biosynthetic process GO:0090407 163 0.038
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.038
positive regulation of mitotic sister chromatid separation GO:1901970 6 0.038
regulation of macrophage fusion GO:0034239 1 0.038
single organism membrane organization GO:0044802 268 0.036
negative regulation of proteolysis GO:0045861 132 0.036
organelle assembly GO:0070925 176 0.036
single organismal cell cell adhesion GO:0016337 148 0.036
positive regulation of cell migration GO:0030335 172 0.036
positive regulation of phosphorylation GO:0042327 394 0.036
chemical homeostasis GO:0048878 306 0.036
regulation of erbb signaling pathway GO:1901184 27 0.035
metaphase plate congression GO:0051310 18 0.035
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.035
positive regulation of cellular component movement GO:0051272 181 0.035
regulation of mitotic sister chromatid segregation GO:0033047 27 0.033
regulation of mitotic sister chromatid separation GO:0010965 27 0.033
response to lipoprotein particle GO:0055094 5 0.032
cell adhesion mediated by integrin GO:0033627 27 0.032
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.032
behavior GO:0007610 112 0.032
cellular response to abiotic stimulus GO:0071214 117 0.031
immune response GO:0006955 307 0.031
negative regulation of cellular component organization GO:0051129 235 0.031
ion transmembrane transport GO:0034220 338 0.031
multicellular organismal aging GO:0010259 3 0.031
regulation of cell adhesion GO:0030155 166 0.030
negative regulation of chromosome organization GO:2001251 48 0.030
receptor mediated endocytosis GO:0006898 84 0.030
segmentation GO:0035282 4 0.030
morphogenesis of an epithelial sheet GO:0002011 12 0.030
positive regulation of chromosome segregation GO:0051984 9 0.030
positive regulation of epithelial cell migration GO:0010634 55 0.030
regulation of protein tyrosine kinase activity GO:0061097 36 0.030
regulation of locomotion GO:0040012 329 0.029
positive regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051437 2 0.029
determination of adult lifespan GO:0008340 2 0.028
glycerolipid metabolic process GO:0046486 107 0.028
positive regulation of exit from mitosis GO:0031536 2 0.027
histone serine phosphorylation GO:0035404 4 0.027
response to other organism GO:0051707 261 0.027
regulation of epithelial cell migration GO:0010632 93 0.027
anatomical structure formation involved in morphogenesis GO:0048646 284 0.027
cell substrate adhesion GO:0031589 132 0.027
regulation of cellular ketone metabolic process GO:0010565 50 0.027
negative regulation of interleukin 8 production GO:0032717 12 0.027
regulation of growth GO:0040008 165 0.027
regulation of cellular protein catabolic process GO:1903362 96 0.026
cell adhesion GO:0007155 325 0.026
mitotic metaphase plate congression GO:0007080 14 0.026
dna repair GO:0006281 198 0.026
positive regulation of cell death GO:0010942 263 0.026
free ubiquitin chain polymerization GO:0010994 2 0.026
mrna metabolic process GO:0016071 175 0.026
regulation of kinase activity GO:0043549 314 0.025
microtubule based process GO:0007017 210 0.025
positive regulation of mitotic metaphase anaphase transition GO:0045842 6 0.025
regulation of chromosome organization GO:0033044 103 0.025
positive regulation of nuclear division GO:0051785 27 0.025
ras protein signal transduction GO:0007265 73 0.025
regulation of peptidase activity GO:0052547 180 0.024
negative regulation of catabolic process GO:0009895 104 0.024
negative regulation of ubiquitin protein transferase activity GO:0051444 8 0.024
regulation of endopeptidase activity GO:0052548 170 0.024
regulation of protein complex assembly GO:0043254 147 0.024
erbb signaling pathway GO:0038127 44 0.023
regulation of anatomical structure morphogenesis GO:0022603 286 0.023
positive regulation of organelle organization GO:0010638 195 0.023
negative regulation of protein catabolic process GO:0042177 59 0.023
nuclear transport GO:0051169 179 0.023
negative regulation of cell cycle phase transition GO:1901988 89 0.023
regulation of dna metabolic process GO:0051052 153 0.023
regulation of mitochondrial membrane potential GO:0051881 23 0.023
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.023
neurogenesis GO:0022008 169 0.023
epithelial cell migration GO:0010631 119 0.022
activation of protein kinase activity GO:0032147 90 0.022
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.022
negative regulation of peptidase activity GO:0010466 91 0.022
regulation of dna recombination GO:0000018 23 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
divalent inorganic cation transport GO:0072511 158 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
metal ion transport GO:0030001 272 0.021
establishment of organelle localization GO:0051656 59 0.021
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.021
proteasomal protein catabolic process GO:0010498 176 0.021
maintenance of protein location in cell GO:0032507 56 0.021
wound healing spreading of epidermal cells GO:0035313 6 0.021
intracellular protein transport GO:0006886 270 0.021
gtp metabolic process GO:0046039 239 0.021
spindle assembly checkpoint GO:0071173 17 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
activation of mapkk activity GO:0000186 18 0.020
response to acid chemical GO:0001101 66 0.020
phospholipid metabolic process GO:0006644 99 0.020
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 6 0.020
fatty acid metabolic process GO:0006631 115 0.020
activation of immune response GO:0002253 114 0.020
defense response GO:0006952 315 0.020
regulation of homeostatic process GO:0032844 121 0.020
negative regulation of mitotic sister chromatid segregation GO:0033048 17 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
response to abiotic stimulus GO:0009628 336 0.020
dna recombination GO:0006310 77 0.020
negative regulation of cellular protein catabolic process GO:1903363 38 0.019
anterior posterior axis specification GO:0009948 2 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.019
response to oxidative stress GO:0006979 121 0.019
regulation of membrane potential GO:0042391 95 0.019
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
membrane organization GO:0061024 292 0.018
epithelium development GO:0060429 227 0.018
protein localization to cytoskeleton GO:0044380 11 0.018
lens development in camera type eye GO:0002088 2 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.018
nitrogen compound transport GO:0071705 191 0.018
chromatin organization GO:0006325 351 0.017
negative regulation of mitosis GO:0045839 24 0.017
negative regulation of mitotic cell cycle GO:0045930 102 0.017
positive regulation of cell adhesion GO:0045785 84 0.017
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.017
post embryonic development GO:0009791 2 0.017
rna 3 end processing GO:0031123 35 0.017
cation transport GO:0006812 331 0.016
blastocyst development GO:0001824 3 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
morphogenesis of an epithelium GO:0002009 60 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
protein localization to microtubule cytoskeleton GO:0072698 10 0.016
regulation of immune response GO:0050776 201 0.016
positive regulation of protein transport GO:0051222 135 0.016
cell projection morphogenesis GO:0048858 129 0.016
negative regulation of endopeptidase activity GO:0010951 84 0.016
small molecule biosynthetic process GO:0044283 157 0.016
single organism nuclear import GO:1902593 104 0.016
negative regulation of cell cycle GO:0045786 193 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
regulation of intracellular transport GO:0032386 195 0.015
mitotic spindle checkpoint GO:0071174 18 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
regulation of epidermal growth factor receptor signaling pathway GO:0042058 27 0.015
regulation of cellular component movement GO:0051270 334 0.015
wound healing spreading of cells GO:0044319 8 0.015
positive regulation of cellular protein catabolic process GO:1903364 37 0.015
peripheral nervous system development GO:0007422 2 0.015
regulation of multi organism process GO:0043900 157 0.015
cellular response to organic cyclic compound GO:0071407 127 0.015
response to corticosteroid GO:0031960 15 0.015
ribonucleotide biosynthetic process GO:0009260 81 0.015
reproductive system development GO:0061458 56 0.015
t cell activation GO:0042110 99 0.015
endocytosis GO:0006897 159 0.015
regulation of microtubule cytoskeleton organization GO:0070507 61 0.014
lipid localization GO:0010876 106 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
protein polymerization GO:0051258 71 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
response to hormone GO:0009725 175 0.014
cell projection organization GO:0030030 252 0.014
epiboly GO:0090504 9 0.014
cellular component disassembly GO:0022411 92 0.014
extrinsic apoptotic signaling pathway GO:0097191 119 0.014
regulation of cell migration GO:0030334 289 0.014
lymphocyte activation GO:0046649 133 0.014
establishment of protein localization to organelle GO:0072594 172 0.013
early endosome to golgi transport GO:0034498 3 0.013
cell type specific apoptotic process GO:0097285 125 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.013
phospholipid biosynthetic process GO:0008654 44 0.013
regulation of cell motility GO:2000145 299 0.013
spindle checkpoint GO:0031577 26 0.013
blastoderm segmentation GO:0007350 2 0.013
negative regulation of organelle organization GO:0010639 126 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
regulation of protein processing GO:0070613 150 0.013
epidermal growth factor receptor signaling pathway GO:0007173 39 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 7 0.013
tissue regeneration GO:0042246 3 0.013
cell aging GO:0007569 52 0.013
cellular protein complex assembly GO:0043623 188 0.013
response to wounding GO:0009611 168 0.013
embryo development ending in birth or egg hatching GO:0009792 34 0.012
cilium assembly GO:0042384 63 0.012
protein import GO:0017038 130 0.012
dephosphorylation GO:0016311 209 0.012
positive regulation of growth GO:0045927 58 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.012
innate immune response GO:0045087 178 0.012
reciprocal dna recombination GO:0035825 4 0.012
biological adhesion GO:0022610 331 0.012
rna interference GO:0016246 4 0.012
phagocytosis GO:0006909 42 0.012
single organism reproductive process GO:0044702 98 0.012
divalent metal ion transport GO:0070838 152 0.011
reproductive process GO:0022414 106 0.011
engulfment of apoptotic cell GO:0043652 2 0.011
defense response to bacterium GO:0042742 63 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
central nervous system neuron axonogenesis GO:0021955 3 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.011
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
secretion by cell GO:0032940 226 0.011
icosanoid metabolic process GO:0006690 35 0.011
mitotic spindle assembly checkpoint GO:0007094 14 0.011
positive regulation of cell cycle phase transition GO:1901989 22 0.011
cellular response to decreased oxygen levels GO:0036294 51 0.011
neuron death GO:0070997 65 0.010
response to radiation GO:0009314 151 0.010
monovalent inorganic cation transport GO:0015672 128 0.010
positive regulation of phospholipid biosynthetic process GO:0071073 4 0.010
maintenance of location in cell GO:0051651 62 0.010
ribonucleoside catabolic process GO:0042454 406 0.010
golgi inheritance GO:0048313 2 0.010

MAD2L2 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.773
eye and adnexa disease DOID:1492 150 0.773
nervous system disease DOID:863 431 0.773
retinal disease DOID:5679 118 0.585
eye disease DOID:5614 149 0.585
retinal degeneration DOID:8466 89 0.551
cancer DOID:162 167 0.066
disease of cellular proliferation DOID:14566 174 0.066
organ system cancer DOID:0050686 164 0.044
gastrointestinal system cancer DOID:3119 52 0.011