|
|
response to nitrosative stress
|
GO:0051409 |
4 |
1.000
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.999
|
Rat Worm Fly |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.999
|
Fly |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.997
|
Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.990
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.986
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.984
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.980
|
Rat Worm Fly |
|
|
tor signaling
|
GO:0031929 |
39 |
0.974
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.945
|
Rat Fly |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.940
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.935
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.931
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.917
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.915
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.903
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.901
|
Fly |
|
|
inactivation of mapk activity
|
GO:0000188 |
5 |
0.888
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.877
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.846
|
|
|
|
jun phosphorylation
|
GO:0007258 |
28 |
0.841
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.839
|
|
|
|
transposition rna mediated
|
GO:0032197 |
0 |
0.834
|
Yeast |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.816
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.801
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.795
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.792
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.791
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.788
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.787
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
14 |
0.782
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.771
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.762
|
|
|
|
macroautophagy
|
GO:0016236 |
39 |
0.757
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.756
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.752
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.743
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.721
|
Yeast |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.717
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.705
|
Mouse |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.683
|
Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.659
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.656
|
Mouse Rat |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.649
|
Mouse Rat |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.644
|
Yeast |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.608
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.606
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.605
|
|
|
|
negative regulation of autophagy
|
GO:0010507 |
14 |
0.602
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.599
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.593
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.570
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.567
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.554
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.545
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.542
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.538
|
|
|
|
negative regulation of macroautophagy
|
GO:0016242 |
4 |
0.537
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.536
|
Rat |
|
|
negative regulation of response to extracellular stimulus
|
GO:0032105 |
5 |
0.530
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.528
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.524
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.515
|
Yeast |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.508
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.503
|
Fly |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.496
|
Yeast |
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.486
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.472
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.466
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.463
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.459
|
|
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
12 |
0.459
|
Rat Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.446
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.442
|
Worm |
|
|
cell development
|
GO:0048468 |
328 |
0.431
|
Rat Fly |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.430
|
Yeast |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.421
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.421
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.416
|
Yeast |
|
|
response to metal ion
|
GO:0010038 |
84 |
0.407
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.403
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.401
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.398
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.377
|
Mouse Rat |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.369
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.368
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.361
|
Rat |
|
|
autophagy
|
GO:0006914 |
88 |
0.350
|
Yeast |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.346
|
Rat |
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.343
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902042 |
15 |
0.343
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.339
|
|
|
|
system process
|
GO:0003008 |
349 |
0.336
|
Rat |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.335
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.331
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.331
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.313
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.307
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.301
|
Mouse |
|
|
negative regulation of response to nutrient levels
|
GO:0032108 |
5 |
0.301
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.301
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.297
|
Rat |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.290
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.286
|
Rat |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.285
|
Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.273
|
Rat |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.272
|
Human |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.272
|
Yeast |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.270
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.266
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.264
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.259
|
|
|
|
peptidyl serine dephosphorylation
|
GO:0070262 |
2 |
0.253
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.252
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.249
|
Yeast |
|
|
visual learning
|
GO:0008542 |
1 |
0.249
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.243
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.243
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.241
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.239
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.238
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.238
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.235
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.232
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.232
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.231
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.229
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.226
|
Rat |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.226
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.226
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.225
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.225
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.224
|
Worm |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.223
|
Yeast |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.222
|
|
|
|
growth
|
GO:0040007 |
202 |
0.221
|
Yeast |
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.221
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.217
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.216
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.213
|
Fly |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.212
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.211
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.210
|
Fly |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.210
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.207
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.206
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.205
|
Rat |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.204
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.204
|
Rat |
|
|
wound healing
|
GO:0042060 |
115 |
0.203
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.202
|
Fly |
|
|
cartilage condensation
|
GO:0001502 |
1 |
0.202
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.199
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.197
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.197
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.195
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.192
|
Yeast |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.192
|
Yeast |
|
|
response to wounding
|
GO:0009611 |
168 |
0.192
|
Rat |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.192
|
Mouse Rat |
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.188
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.188
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.188
|
Mouse |
|
|
neurological system process
|
GO:0050877 |
163 |
0.187
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.186
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.185
|
Rat |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.180
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.180
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.178
|
|
|
|
positive regulation of adenylate cyclase activity
|
GO:0045762 |
12 |
0.177
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.176
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.176
|
Fly |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.175
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.170
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.168
|
Rat |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.168
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.166
|
Yeast |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.165
|
Rat Fly |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.160
|
Fly |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.160
|
Human |
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.158
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.158
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.155
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.152
|
Rat |
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.151
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.151
|
Worm |
|
|
gastrulation
|
GO:0007369 |
51 |
0.149
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.149
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.148
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
17 |
0.147
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.145
|
Rat |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.144
|
Worm |
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.143
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.139
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.138
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.136
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.136
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.135
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.135
|
Yeast |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.134
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.133
|
Mouse Worm |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.131
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.129
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.128
|
Mouse |
|
|
negative regulation of small gtpase mediated signal transduction
|
GO:0051058 |
12 |
0.127
|
|
|
|
arachidonic acid metabolic process
|
GO:0019369 |
14 |
0.127
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.126
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.125
|
Mouse Worm Fly |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.122
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.122
|
Rat |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.122
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.121
|
Mouse |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.121
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.120
|
Rat |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.119
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.117
|
|
|
|
cellular response to calcium ion
|
GO:0071277 |
19 |
0.117
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.116
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.115
|
Human |
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.115
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.115
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.113
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.111
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.109
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.109
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.108
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.107
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.107
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.106
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.105
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.105
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.105
|
|
|
|
histone h2a s1 phosphorylation
|
GO:0043990 |
1 |
0.104
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.104
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.103
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.103
|
Rat |
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.103
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.102
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.102
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.098
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.096
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.094
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.094
|
Yeast Rat |
|
|
developmental growth
|
GO:0048589 |
48 |
0.093
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.093
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.093
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.092
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.092
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.091
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.091
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.090
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.090
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
28 |
0.090
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.090
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.090
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.089
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.089
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.088
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.088
|
Rat |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.088
|
Rat |
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.088
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.087
|
|
|
|
interleukin 1 mediated signaling pathway
|
GO:0070498 |
12 |
0.087
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.086
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.086
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.086
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.085
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.084
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.084
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.084
|
|
|
|
positive regulation of wound healing
|
GO:0090303 |
20 |
0.083
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.082
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.082
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.082
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.081
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.080
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.079
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.079
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.078
|
|
|
|
negative regulation of t cell receptor signaling pathway
|
GO:0050860 |
4 |
0.078
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.077
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.076
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.076
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.076
|
|
|
|
mapk import into nucleus
|
GO:0000189 |
1 |
0.075
|
Yeast |
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.075
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.075
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.075
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.075
|
Rat |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.075
|
|
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
3 |
0.074
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.073
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.073
|
|
|
|
regulation of response to nutrient levels
|
GO:0032107 |
22 |
0.073
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.073
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.072
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.072
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.072
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.072
|
Yeast |
|
|
regulation of transcription by galactose
|
GO:0000409 |
1 |
0.071
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.070
|
Yeast |
|
|
regionalization
|
GO:0003002 |
29 |
0.070
|
Fly |
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.069
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.069
|
|
|
|
mapk export from nucleus
|
GO:0045204 |
1 |
0.069
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.069
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.069
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.068
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.067
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.066
|
Rat |
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
24 |
0.066
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.066
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.066
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.065
|
Rat |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.065
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.065
|
Yeast |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.065
|
|
|
|
positive regulation of histone phosphorylation
|
GO:0033129 |
3 |
0.064
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.063
|
Rat |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.063
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.062
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.062
|
Rat |
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.062
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.061
|
Rat |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.060
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.060
|
Rat |
|
|
cell activation
|
GO:0001775 |
213 |
0.060
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.060
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.060
|
|
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
12 |
0.059
|
Rat Fly |
|
|
regulation of response to extracellular stimulus
|
GO:0032104 |
22 |
0.059
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.059
|
Mouse |
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.058
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.058
|
Rat |
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.058
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.058
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.057
|
Yeast |
|
|
cell fate specification
|
GO:0001708 |
8 |
0.057
|
|
|
|
skeletal muscle tissue regeneration
|
GO:0043403 |
2 |
0.057
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.057
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.056
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.056
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.056
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.056
|
Rat |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.056
|
Rat |
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.056
|
Rat |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.055
|
Rat |
|
|
mucosal immune response
|
GO:0002385 |
21 |
0.055
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.054
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.054
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.053
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.053
|
|
|
|
head development
|
GO:0060322 |
108 |
0.053
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.053
|
|
|
|
histone phosphorylation
|
GO:0016572 |
16 |
0.052
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.052
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.052
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.052
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.051
|
Rat |
|
|
histone serine phosphorylation
|
GO:0035404 |
4 |
0.051
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.051
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.050
|
|
|
|
cell aggregation
|
GO:0098743 |
1 |
0.050
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.050
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.050
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.049
|
|
|
|
response to epidermal growth factor
|
GO:0070849 |
14 |
0.049
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.049
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.049
|
Rat |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.049
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.049
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.048
|
Rat |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.048
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.048
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.048
|
Rat |
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.047
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.047
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.047
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.047
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.046
|
|
|
|
regulation of histone phosphorylation
|
GO:0033127 |
5 |
0.046
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.046
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.046
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.046
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.046
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.045
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.045
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.045
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.044
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.044
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.044
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.044
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.044
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.044
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.044
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.044
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.043
|
Rat |
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.043
|
|
|
|
membrane raft localization
|
GO:0051665 |
1 |
0.043
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.043
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.043
|
Rat |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.043
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.043
|
Yeast |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.043
|
|
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.042
|
Rat |
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.042
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.042
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.042
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.042
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.041
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.041
|
Rat |
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.041
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.041
|
|
|
|
disruption of cells of other organism involved in symbiotic interaction
|
GO:0051818 |
3 |
0.040
|
|
|
|
centrosome separation
|
GO:0051299 |
3 |
0.040
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.040
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.040
|
Rat |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.040
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.040
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.040
|
Rat |
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.040
|
Rat |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.039
|
|
|
|
positive regulation of ruffle assembly
|
GO:1900029 |
4 |
0.039
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.039
|
Mouse |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.039
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.039
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.039
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.039
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.038
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.038
|
Rat |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.038
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.038
|
Yeast Mouse Worm Fly |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.038
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.038
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
5 |
0.037
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.037
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.037
|
|
|
|
regulation of developmental pigmentation
|
GO:0048070 |
2 |
0.037
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.037
|
|
|
|
positive regulation of hepatic stellate cell activation
|
GO:2000491 |
1 |
0.037
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.036
|
|
|
|
long chain fatty acid metabolic process
|
GO:0001676 |
30 |
0.036
|
|
|
|
dna damage induced protein phosphorylation
|
GO:0006975 |
5 |
0.036
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.035
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.035
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.034
|
Rat |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.034
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.034
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.034
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.034
|
Rat |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.034
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.033
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.033
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.033
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.032
|
Rat |
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
2 |
0.032
|
|
|
|
translational initiation
|
GO:0006413 |
48 |
0.032
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.032
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.031
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.031
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.031
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.031
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.031
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.031
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.031
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.031
|
Rat |
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.031
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.030
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.030
|
Rat |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.030
|
|
|
|
regulation of cell fate commitment
|
GO:0010453 |
7 |
0.030
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.030
|
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.030
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.030
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.030
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.030
|
|
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
17 |
0.030
|
|
|
|
cellular hyperosmotic response
|
GO:0071474 |
4 |
0.029
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.029
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.029
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.029
|
|
|
|
regulation of peptidyl serine dephosphorylation
|
GO:1902308 |
2 |
0.029
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.029
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.029
|
|
