Homo sapiens

0 known processes

MAP2K5

mitogen-activated protein kinase kinase 5

(Aliases: HsT17454,PRKMK5,MEK5,MAPKK5)

MAP2K5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of p38mapk cascade GO:1900745 8 0.862
mapk cascade GO:0000165 288 0.751
Mouse Rat
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.637
regulation of heterotypic cell cell adhesion GO:0034114 14 0.620
Rat
protein autophosphorylation GO:0046777 123 0.479
glutamine family amino acid catabolic process GO:0009065 8 0.478
signal transduction by phosphorylation GO:0023014 297 0.362
Mouse Rat
nuclear transport GO:0051169 179 0.356
cellular response to laminar fluid shear stress GO:0071499 5 0.338
regulation of apoptotic signaling pathway GO:2001233 175 0.337
Rat
regulation of protein targeting GO:1903533 91 0.336
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.293
Rat
glutamine family amino acid metabolic process GO:0009064 17 0.277
protein targeting GO:0006605 187 0.275
negative regulation of transport GO:0051051 176 0.272
cellular amino acid metabolic process GO:0006520 116 0.267
angiogenesis GO:0001525 147 0.236
Rat
protein targeting to nucleus GO:0044744 104 0.233
regulation of oxidative stress induced cell death GO:1903201 24 0.229
cell cell adhesion involved in gastrulation GO:0070586 6 0.226
Rat
vasculature development GO:0001944 181 0.222
Rat
positive regulation of mapk cascade GO:0043410 190 0.221
Rat
establishment of protein localization to organelle GO:0072594 172 0.217
negative regulation of apoptotic signaling pathway GO:2001234 97 0.216
Rat
positive regulation of protein kinase activity GO:0045860 190 0.216
Rat
regulation of protein localization GO:0032880 296 0.212
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.207
Rat
anatomical structure formation involved in morphogenesis GO:0048646 284 0.202
Rat
heterotypic cell cell adhesion GO:0034113 28 0.201
Rat
aspartate family amino acid catabolic process GO:0009068 5 0.199
protein import into nucleus GO:0006606 104 0.199
small molecule catabolic process GO:0044282 92 0.194
alpha amino acid metabolic process GO:1901605 72 0.194
regulation of establishment of protein localization GO:0070201 242 0.190
regulation of protein kinase activity GO:0045859 289 0.189
Rat
tube development GO:0035295 125 0.187
Rat
regulation of nucleocytoplasmic transport GO:0046822 98 0.183
regulation of angiogenesis GO:0045765 92 0.178
Rat
single organismal cell cell adhesion GO:0016337 148 0.177
Rat
nuclear import GO:0051170 106 0.177
positive regulation of apoptotic process GO:0043065 246 0.176
cellular response to oxidative stress GO:0034599 85 0.170
negative regulation of apoptotic process GO:0043066 316 0.170
Rat
regulation of transcription factor import into nucleus GO:0042990 39 0.168
single organism cellular localization GO:1902580 332 0.166
cell death in response to oxidative stress GO:0036473 29 0.152
cellular response to fluid shear stress GO:0071498 7 0.151
regulation of mapk cascade GO:0043408 262 0.151
Rat
asymmetric neuroblast division GO:0055059 1 0.149
neuroblast division GO:0055057 1 0.143
regulation of anatomical structure morphogenesis GO:0022603 286 0.141
Rat
extrinsic apoptotic signaling pathway GO:0097191 119 0.140
Rat
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.140
Rat
negative regulation of intracellular signal transduction GO:1902532 183 0.140
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.136
Rat
regulation of protein transport GO:0051223 213 0.134
signal transduction in absence of ligand GO:0038034 22 0.130
Rat
cell adhesion GO:0007155 325 0.130
Rat
negative regulation of protein transport GO:0051224 75 0.126
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.124
carboxylic acid catabolic process GO:0046395 71 0.122
activation of protein kinase activity GO:0032147 90 0.121
Rat
regulation of cell cell adhesion involved in gastrulation GO:0070587 6 0.120
Rat
positive regulation of phosphorylation GO:0042327 394 0.118
Rat
positive regulation of transferase activity GO:0051347 227 0.113
Rat
i kappab kinase nf kappab signaling GO:0007249 166 0.108
ras protein signal transduction GO:0007265 73 0.102
organic acid catabolic process GO:0016054 71 0.102
intracellular protein transport GO:0006886 270 0.098
cellular response to endogenous stimulus GO:0071495 336 0.098
regulation of locomotion GO:0040012 329 0.097
Rat
blood vessel morphogenesis GO:0048514 162 0.097
Rat
negative regulation of cell adhesion GO:0007162 64 0.096
Rat
positive regulation of cellular component organization GO:0051130 376 0.096
regulation of intracellular transport GO:0032386 195 0.096
cellular response to oxygen containing compound GO:1901701 276 0.095
regulation of cellular response to stress GO:0080135 244 0.092
response to growth factor GO:0070848 205 0.090
Rat
negative regulation of programmed cell death GO:0043069 321 0.089
Rat
cellular response to reactive oxygen species GO:0034614 50 0.087
response to oxygen containing compound GO:1901700 369 0.087
cytoplasmic transport GO:0016482 379 0.086
nucleocytoplasmic transport GO:0006913 176 0.083
negative regulation of response to cytokine stimulus GO:0060761 25 0.082
Rat
ribonucleoside triphosphate metabolic process GO:0009199 412 0.082
negative regulation of phosphate metabolic process GO:0045936 267 0.082
regulation of ion transmembrane transport GO:0034765 132 0.081
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.080
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.080
Rat
response to abiotic stimulus GO:0009628 336 0.077
circulatory system development GO:0072359 262 0.077
Mouse Rat
cellular macromolecular complex assembly GO:0034622 324 0.076
positive regulation of protein phosphorylation GO:0001934 313 0.076
Rat
cellular response to mechanical stimulus GO:0071260 39 0.076
cardiovascular system development GO:0072358 262 0.074
Mouse Rat
organophosphate catabolic process GO:0046434 430 0.074
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.073
neuroblast proliferation GO:0007405 4 0.073
biological adhesion GO:0022610 331 0.073
Rat
regulation of cell cell adhesion GO:0022407 57 0.072
Rat
endothelial cell apoptotic process GO:0072577 26 0.072
protein ubiquitination GO:0016567 314 0.072
single organism nuclear import GO:1902593 104 0.071
regulation of protein import into nucleus GO:0042306 78 0.069
embryonic morphogenesis GO:0048598 85 0.067
Rat
blood vessel development GO:0001568 172 0.067
Rat
response to reactive oxygen species GO:0000302 61 0.065
gastrulation GO:0007369 51 0.065
Rat
purine ribonucleoside metabolic process GO:0046128 437 0.064
microtubule based process GO:0007017 210 0.064
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.064
purine containing compound catabolic process GO:0072523 411 0.063
positive regulation of catabolic process GO:0009896 310 0.063
cellular amino acid catabolic process GO:0009063 31 0.063
purine nucleoside catabolic process GO:0006152 398 0.063
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.062
Rat
ion transmembrane transport GO:0034220 338 0.062
response to oxidative stress GO:0006979 121 0.060
regulation of response to oxidative stress GO:1902882 26 0.057
digestive system development GO:0055123 75 0.057
Rat
cellular response to growth factor stimulus GO:0071363 197 0.056
Rat
positive regulation of transport GO:0051050 336 0.055
protein localization to organelle GO:0033365 280 0.054
negative regulation of oxidative stress induced cell death GO:1903202 17 0.054
regulation of cellular response to oxidative stress GO:1900407 26 0.053
alpha amino acid catabolic process GO:1901606 26 0.053
post embryonic development GO:0009791 2 0.052
Worm
carbohydrate metabolic process GO:0005975 207 0.051
regulation of cell adhesion GO:0030155 166 0.051
Rat
positive regulation of vascular endothelial growth factor signaling pathway GO:1900748 3 0.050
purine nucleoside triphosphate metabolic process GO:0009144 412 0.049
regulation of cytoplasmic transport GO:1903649 149 0.049
negative regulation of heterotypic cell cell adhesion GO:0034115 6 0.048
Rat
positive regulation of nucleotide catabolic process GO:0030813 185 0.048
intrinsic apoptotic signaling pathway GO:0097193 127 0.048
nucleotide catabolic process GO:0009166 408 0.048
negative regulation of protein import into nucleus GO:0042308 30 0.047
negative regulation of cellular response to oxidative stress GO:1900408 18 0.046
cellular response to abiotic stimulus GO:0071214 117 0.046
peptidyl serine phosphorylation GO:0018105 101 0.046
g protein coupled receptor signaling pathway GO:0007186 207 0.044
cellular response to hydrogen peroxide GO:0070301 37 0.044
transcription factor import into nucleus GO:0042991 40 0.044
response to fluid shear stress GO:0034405 14 0.044
regulation of response to cytokine stimulus GO:0060759 46 0.043
Rat
regulation of intracellular protein transport GO:0033157 123 0.043
determination of adult lifespan GO:0008340 2 0.043
regulation of cell differentiation GO:0045595 393 0.043
carbohydrate derivative biosynthetic process GO:1901137 207 0.043
response to light stimulus GO:0009416 87 0.042
nucleoside phosphate catabolic process GO:1901292 412 0.042
negative regulation of protein metabolic process GO:0051248 391 0.042
Rat
negative regulation of protein modification process GO:0031400 200 0.042
positive regulation of locomotion GO:0040017 186 0.042
positive regulation of gtpase activity GO:0043547 166 0.041
regulation of protein localization to nucleus GO:1900180 85 0.041
regulation of endothelial cell apoptotic process GO:2000351 24 0.040
cell morphogenesis GO:0000902 296 0.040
positive regulation of intracellular protein transport GO:0090316 76 0.040
atp metabolic process GO:0046034 176 0.040
forebrain generation of neurons GO:0021872 3 0.040
negative regulation of response to oxidative stress GO:1902883 18 0.039
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 9 0.039
regulation of cellular component biogenesis GO:0044087 281 0.039
mitotic cell cycle process GO:1903047 286 0.039
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.039
negative regulation of cellular protein metabolic process GO:0032269 353 0.038
Rat
nucleoside triphosphate metabolic process GO:0009141 422 0.038
amine metabolic process GO:0009308 44 0.038
nucleus localization GO:0051647 1 0.038
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.037
ribonucleoside triphosphate catabolic process GO:0009203 391 0.037
regulation of cellular ketone metabolic process GO:0010565 50 0.037
digestive tract morphogenesis GO:0048546 56 0.036
Rat
somatic stem cell division GO:0048103 1 0.035
taxis GO:0042330 157 0.035
negative regulation of cell cell adhesion GO:0022408 27 0.035
Rat
neuronal stem cell division GO:0036445 1 0.034
cell cell junction organization GO:0045216 69 0.034
purine ribonucleoside catabolic process GO:0046130 398 0.034
cellular response to external stimulus GO:0071496 111 0.034
neuromuscular junction development GO:0007528 3 0.034
cellular response to cytokine stimulus GO:0071345 181 0.034
forelimb morphogenesis GO:0035136 4 0.034
regulation of cellular component movement GO:0051270 334 0.034
Rat
cell development GO:0048468 328 0.034
lipid metabolic process GO:0006629 381 0.033
digestive tract development GO:0048565 75 0.033
Rat
peptidyl serine modification GO:0018209 106 0.033
negative regulation of developmental process GO:0051093 247 0.032
Rat
ribonucleoside monophosphate metabolic process GO:0009161 187 0.032
regulation of nucleotide metabolic process GO:0006140 269 0.032
positive regulation of protein transport GO:0051222 135 0.032
negative regulation of cell death GO:0060548 345 0.032
Rat
response to laminar fluid shear stress GO:0034616 8 0.031
monocarboxylic acid metabolic process GO:0032787 185 0.031
positive regulation of programmed cell death GO:0043068 249 0.031
activation of mapkkk activity GO:0000185 7 0.030
positive regulation of cellular component movement GO:0051272 181 0.030
cellular protein catabolic process GO:0044257 261 0.030
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 16 0.029
purine nucleoside monophosphate metabolic process GO:0009126 186 0.029
cellular lipid metabolic process GO:0044255 303 0.029
regulation of gastrulation GO:0010470 12 0.029
Rat
neurological system process GO:0050877 163 0.029
atp catabolic process GO:0006200 157 0.029
positive regulation of cell motility GO:2000147 177 0.029
response to cytokine GO:0034097 232 0.028
Rat
cell junction organization GO:0034330 79 0.028
associative learning GO:0008306 1 0.028
positive regulation of intracellular transport GO:0032388 104 0.028
oxidation reduction process GO:0055114 396 0.028
regulation of cytoskeleton organization GO:0051493 177 0.028
transmembrane transport GO:0055085 399 0.028
negative regulation of transcription factor import into nucleus GO:0042992 17 0.027
regulation of embryonic development GO:0045995 20 0.027
Rat
action potential GO:0001508 34 0.027
regulation of leukocyte activation GO:0002694 115 0.027
regulation of peptidase activity GO:0052547 180 0.027
Rat
negative regulation of catalytic activity GO:0043086 335 0.026
Rat
ribonucleotide catabolic process GO:0009261 405 0.026
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.026
negative regulation of intracellular protein transport GO:0090317 42 0.026
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.026
positive regulation of ion transport GO:0043270 87 0.025
chemical homeostasis GO:0048878 306 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.025
embryonic epithelial tube formation GO:0001838 4 0.025
rna processing GO:0006396 255 0.025
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.025
Rat
adult locomotory behavior GO:0008344 1 0.025
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.025
establishment of protein localization to membrane GO:0090150 121 0.025
female gamete generation GO:0007292 2 0.024
chemotaxis GO:0006935 157 0.024
negative regulation of protein phosphorylation GO:0001933 140 0.024
monovalent inorganic cation transport GO:0015672 128 0.024
stress activated mapk cascade GO:0051403 93 0.024
response to radiation GO:0009314 151 0.024
cellular ketone metabolic process GO:0042180 80 0.023
glycosyl compound catabolic process GO:1901658 413 0.023
mitotic cell cycle GO:0000278 326 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
reactive nitrogen species metabolic process GO:2001057 3 0.023
regulation of protein complex assembly GO:0043254 147 0.023
negative regulation of endothelial cell apoptotic process GO:2000352 16 0.023
negative regulation of protein localization to nucleus GO:1900181 34 0.023
response to hormone GO:0009725 175 0.023
regulation of dna templated transcription in response to stress GO:0043620 18 0.023
secretion GO:0046903 254 0.022
positive regulation of cellular component biogenesis GO:0044089 158 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
regulation of actin cytoskeleton organization GO:0032956 116 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
phospholipid catabolic process GO:0009395 12 0.022
response to hydrogen peroxide GO:0042542 40 0.022
response to mechanical stimulus GO:0009612 51 0.022
positive regulation of organelle organization GO:0010638 195 0.022
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
Rat
regulation of small gtpase mediated signal transduction GO:0051056 156 0.021
microtubule cytoskeleton organization GO:0000226 176 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
growth GO:0040007 202 0.021
Rat
regulation of carbohydrate metabolic process GO:0006109 54 0.021
regulation of stress activated mapk cascade GO:0032872 84 0.021
negative regulation of cellular amine metabolic process GO:0033239 3 0.021
establishment of nucleus localization GO:0040023 1 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 10 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.020
protein localization to nucleus GO:0034504 136 0.020
regulation of p38mapk cascade GO:1900744 9 0.020
vesicle mediated transport GO:0016192 371 0.020
hindbrain development GO:0030902 3 0.020
negative regulation of organelle organization GO:0010639 126 0.020
regulation of cell development GO:0060284 161 0.020
regulation of dna metabolic process GO:0051052 153 0.020
response to transforming growth factor beta GO:0071559 94 0.020
regulation of secretion GO:0051046 194 0.020
ribonucleoside monophosphate catabolic process GO:0009158 158 0.020
protein processing GO:0016485 226 0.020
Rat
myeloid cell differentiation GO:0030099 117 0.020
morphogenesis of embryonic epithelium GO:0016331 4 0.020
regulation of potassium ion transmembrane transport GO:1901379 20 0.020
locomotory behavior GO:0007626 1 0.019
cellular calcium ion homeostasis GO:0006874 117 0.019
negative regulation of proteolysis GO:0045861 132 0.019
Rat
actin cytoskeleton organization GO:0030036 207 0.019
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 17 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
response to inorganic substance GO:0010035 127 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.019
dephosphorylation GO:0016311 209 0.019
organelle assembly GO:0070925 176 0.019
regulation of cysteine type endopeptidase activity GO:2000116 127 0.019
Rat
regulation of protein serine threonine kinase activity GO:0071900 179 0.019
Rat
cell type specific apoptotic process GO:0097285 125 0.019
regulation of lymphocyte activation GO:0051249 103 0.019
regulation of cell motility GO:2000145 299 0.019
Rat
nucleotide biosynthetic process GO:0009165 109 0.019
cellular polysaccharide metabolic process GO:0044264 27 0.018
maintenance of location GO:0051235 112 0.018
reactive oxygen species biosynthetic process GO:1903409 4 0.018
memory GO:0007613 3 0.018
positive regulation of stress activated mapk cascade GO:0032874 60 0.018
regulation of kinase activity GO:0043549 314 0.018
Rat
regulation of reactive oxygen species metabolic process GO:2000377 41 0.018
regulation of cell cycle GO:0051726 393 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
secretion by cell GO:0032940 226 0.018
cellular amine metabolic process GO:0044106 41 0.018
positive regulation of cytoplasmic transport GO:1903651 82 0.018
peptidyl tyrosine modification GO:0018212 170 0.018
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.018
striated muscle contraction GO:0006941 52 0.018
lipid biosynthetic process GO:0008610 177 0.018
regulation of interleukin 13 secretion GO:2000665 2 0.017
cellular response to hormone stimulus GO:0032870 125 0.017
cellular potassium ion transport GO:0071804 60 0.017
cell fate determination GO:0001709 3 0.017
hippocampus development GO:0021766 1 0.017
protein dephosphorylation GO:0006470 81 0.017
asymmetric stem cell division GO:0098722 1 0.017
regulation of proteolysis GO:0030162 293 0.017
Rat
cation homeostasis GO:0055080 189 0.017
actin filament based process GO:0030029 224 0.017
regulation of vasculature development GO:1901342 97 0.017
Rat
gtp metabolic process GO:0046039 239 0.017
organonitrogen compound biosynthetic process GO:1901566 200 0.017
segmentation GO:0035282 4 0.017
positive regulation of synaptic transmission GO:0050806 4 0.017
regulation of dephosphorylation GO:0035303 96 0.017
protein localization to membrane GO:0072657 160 0.017
regulation of cell cycle process GO:0010564 266 0.017
positive regulation of cell migration GO:0030335 172 0.017
regulation of response to external stimulus GO:0032101 222 0.017
actin polymerization or depolymerization GO:0008154 56 0.017
developmental programmed cell death GO:0010623 3 0.017
midgut development GO:0007494 1 0.017
positive regulation of interleukin 5 production GO:0032754 3 0.016
ribonucleoside catabolic process GO:0042454 406 0.016
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.016
interleukin 13 secretion GO:0072611 2 0.016
calcium ion homeostasis GO:0055074 122 0.016
nuclear division GO:0000280 128 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
negative regulation of transferase activity GO:0051348 124 0.016
positive regulation of cell development GO:0010720 92 0.016
regulation of epithelial cell migration GO:0010632 93 0.016
Rat
mitotic nuclear division GO:0007067 119 0.016
positive regulation of ion transmembrane transport GO:0034767 40 0.016
negative regulation of cytoplasmic transport GO:1903650 46 0.016
regulation of cellular amine metabolic process GO:0033238 11 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.016
Rat
protein import GO:0017038 130 0.016
regulation of synaptic plasticity GO:0048167 3 0.016
p38mapk cascade GO:0038066 9 0.016
reproductive process GO:0022414 106 0.016
Worm
protein polymerization GO:0051258 71 0.016
protein oligomerization GO:0051259 173 0.016
regulation of membrane potential GO:0042391 95 0.016
spinal cord development GO:0021510 4 0.016
golgi vesicle transport GO:0048193 80 0.016
response to interleukin 6 GO:0070741 15 0.016
organic anion transport GO:0015711 103 0.015
protein targeting to membrane GO:0006612 42 0.015
calcium ion transport GO:0006816 147 0.015
regulation of erk1 and erk2 cascade GO:0070372 99 0.015
regulation of ras gtpase activity GO:0032318 128 0.015
spermatid differentiation GO:0048515 4 0.015
cell projection morphogenesis GO:0048858 129 0.015
generation of precursor metabolites and energy GO:0006091 68 0.015
immune response GO:0006955 307 0.015
epithelium migration GO:0090132 119 0.015
Rat
regulation of homeostatic process GO:0032844 121 0.015
regulation of cell growth GO:0001558 135 0.015
Rat
mrna metabolic process GO:0016071 175 0.015
cell junction assembly GO:0034329 67 0.015
erk1 and erk2 cascade GO:0070371 104 0.015
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.015
actin filament based movement GO:0030048 17 0.015
apical junction assembly GO:0043297 19 0.015
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.015
organ formation GO:0048645 3 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
Rat
nucleoside monophosphate catabolic process GO:0009125 159 0.014
cation transport GO:0006812 331 0.014
cell activation GO:0001775 213 0.014
positive regulation of developmental process GO:0051094 314 0.014
immune system development GO:0002520 195 0.014
negative regulation of dephosphorylation GO:0035305 63 0.014
epithelial cell differentiation GO:0030855 141 0.014
negative regulation of protein processing GO:0010955 142 0.014
Rat
single organism membrane organization GO:0044802 268 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
regulation of protein processing GO:0070613 150 0.014
Rat
regulation of camp biosynthetic process GO:0030817 45 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
organelle localization GO:0051640 84 0.014
cell projection assembly GO:0030031 126 0.014
neurotransmitter secretion GO:0007269 4 0.014
regulation of meiotic cell cycle GO:0051445 4 0.014
embryo development GO:0009790 123 0.014
Rat
endomembrane system organization GO:0010256 196 0.014
second messenger mediated signaling GO:0019932 78 0.014
response to hypoxia GO:0001666 96 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
fatty acid metabolic process GO:0006631 115 0.014
cellular cation homeostasis GO:0030003 163 0.013
stem cell division GO:0017145 2 0.013
membrane hyperpolarization GO:0060081 1 0.013
tissue migration GO:0090130 119 0.013
Rat
pharynx development GO:0060465 1 0.013
cellular carbohydrate metabolic process GO:0044262 84 0.013
system process GO:0003008 349 0.013
neural tube formation GO:0001841 3 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.013
stress activated protein kinase signaling cascade GO:0031098 94 0.013
regulation of tor signaling GO:0032006 30 0.013
neuron development GO:0048666 113 0.013
leukocyte activation GO:0045321 164 0.013
regulation of protein ubiquitination GO:0031396 95 0.013
regulation of cellular component size GO:0032535 82 0.013
cellular macromolecule catabolic process GO:0044265 380 0.013
cellular protein complex assembly GO:0043623 188 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
cell cycle phase transition GO:0044770 173 0.013
apoptotic signaling pathway GO:0097190 268 0.013
Rat
modification dependent protein catabolic process GO:0019941 209 0.013
hexose metabolic process GO:0019318 55 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
membrane organization GO:0061024 292 0.013
membrane lipid metabolic process GO:0006643 53 0.013
nervous system development GO:0007399 293 0.012
regulation of cellular amino acid metabolic process GO:0006521 6 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
positive regulation of alpha beta t cell differentiation GO:0046638 4 0.012
nitrogen compound transport GO:0071705 191 0.012
negative regulation of nfat protein import into nucleus GO:0051534 2 0.012
nucleoside phosphate biosynthetic process GO:1901293 109 0.012
ameboidal type cell migration GO:0001667 135 0.012
Rat
endosomal transport GO:0016197 129 0.012
multi organism cellular process GO:0044764 156 0.012
leukocyte migration GO:0050900 107 0.012
spermatid development GO:0007286 4 0.012
ectodermal placode development GO:0071696 1 0.012
lymphocyte activation GO:0046649 133 0.012
circadian behavior GO:0048512 2 0.012
regulation of lipid metabolic process GO:0019216 96 0.012
ethanolamine containing compound metabolic process GO:0042439 26 0.012
forebrain neuron differentiation GO:0021879 3 0.012
regulation of ion transmembrane transporter activity GO:0032412 72 0.012
regulation of cell division GO:0051302 116 0.012
oocyte development GO:0048599 1 0.012
glial cell migration GO:0008347 4 0.012
oogenesis GO:0048477 2 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
negative regulation of t cell apoptotic process GO:0070233 4 0.012
maintenance of location in cell GO:0051651 62 0.012
alcohol metabolic process GO:0006066 114 0.012
heart formation GO:0060914 2 0.011
regeneration GO:0031099 4 0.011
regulation of multi organism process GO:0043900 157 0.011
pattern specification process GO:0007389 43 0.011
cellular chemical homeostasis GO:0055082 180 0.011
embryonic hindlimb morphogenesis GO:0035116 2 0.011
negative regulation of cell cycle process GO:0010948 121 0.011
positive regulation of cell death GO:0010942 263 0.011

MAP2K5 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.043
inherited metabolic disorder DOID:655 242 0.043
disease of cellular proliferation DOID:14566 174 0.024
cancer DOID:162 167 0.024
organ system cancer DOID:0050686 164 0.024
sensory system disease DOID:0050155 203 0.021
eye and adnexa disease DOID:1492 150 0.021
nervous system disease DOID:863 431 0.021
eye disease DOID:5614 149 0.021
urinary system disease DOID:18 40 0.017
central nervous system disease DOID:331 186 0.015
musculoskeletal system disease DOID:17 223 0.015
connective tissue disease DOID:65 109 0.015
retinal disease DOID:5679 118 0.014
kidney disease DOID:557 36 0.014
retinal degeneration DOID:8466 89 0.014
cardiovascular system disease DOID:1287 106 0.012
auditory system disease DOID:2742 53 0.012