Homo sapiens

98 known processes

MAP2K7

mitogen-activated protein kinase kinase 7

(Aliases: Jnkk2,PRKMK7,MAPKK7,MKK7)

MAP2K7 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of jun kinase activity GO:0043508 4 0.895
jnk cascade GO:0007254 80 0.766
Mouse Rat Worm Fly
stress activated protein kinase signaling cascade GO:0031098 94 0.735
regulation of protein kinase activity GO:0045859 289 0.728
regulation of jnk cascade GO:0046328 73 0.723
Mouse Rat Worm Fly
positive regulation of map kinase activity GO:0043406 80 0.711
activation of protein kinase activity GO:0032147 90 0.700
regulation of map kinase activity GO:0043405 108 0.648
regulation of stress activated mapk cascade GO:0032872 84 0.620
Mouse Rat Worm Fly
regulation of protein serine threonine kinase activity GO:0071900 179 0.610
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.595
Mouse Rat Worm Fly
signal transduction by phosphorylation GO:0023014 297 0.557
jun phosphorylation GO:0007258 28 0.556
Mouse Rat Worm Fly
positive regulation of protein phosphorylation GO:0001934 313 0.551
axon cargo transport GO:0008088 2 0.537
positive regulation of mapk cascade GO:0043410 190 0.524
response to nitric oxide GO:0071731 4 0.506
positive regulation of protein kinase activity GO:0045860 190 0.474
mapk cascade GO:0000165 288 0.446
collateral sprouting GO:0048668 2 0.437
regulation of mapk cascade GO:0043408 262 0.434
negative regulation of catalytic activity GO:0043086 335 0.426
positive regulation of transferase activity GO:0051347 227 0.405
positive regulation of phosphorylation GO:0042327 394 0.404
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.401
positive regulation of kinase activity GO:0033674 204 0.397
activation of mapk activity GO:0000187 45 0.392
regulation of jun kinase activity GO:0043506 27 0.381
Mouse Rat Worm Fly
apoptotic signaling pathway GO:0097190 268 0.372
covalent chromatin modification GO:0016569 254 0.372
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.311
regulation of transferase activity GO:0051338 355 0.304
activation of jnkk activity GO:0007256 1 0.298
positive regulation of jun kinase activity GO:0043507 23 0.296
Mouse Rat Worm Fly
negative regulation of jnk cascade GO:0046329 16 0.293
positive regulation of stress activated mapk cascade GO:0032874 60 0.290
Mouse Rat Worm Fly
regulation of kinase activity GO:0043549 314 0.289
negative regulation of protein phosphorylation GO:0001933 140 0.280
negative regulation of phosphate metabolic process GO:0045936 267 0.273
negative regulation of protein metabolic process GO:0051248 391 0.272
negative regulation of phosphorus metabolic process GO:0010563 267 0.268
stress activated mapk cascade GO:0051403 93 0.244
cellular macromolecular complex assembly GO:0034622 324 0.235
negative regulation of stress activated mapk cascade GO:0032873 19 0.234
synaptic vesicle transport GO:0048489 5 0.233
post embryonic development GO:0009791 2 0.229
Fly
negative regulation of phosphorylation GO:0042326 174 0.227
cell morphogenesis GO:0000902 296 0.225
Fly
positive regulation of jnk cascade GO:0046330 52 0.216
Mouse Rat Worm Fly
cell cell signaling GO:0007267 155 0.212
regulation of apoptotic signaling pathway GO:2001233 175 0.208
cell development GO:0048468 328 0.202
Fly
nervous system development GO:0007399 293 0.197
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.196
chromatin modification GO:0016568 298 0.189
negative regulation of protein modification process GO:0031400 200 0.183
cellular component morphogenesis GO:0032989 314 0.182
Fly
negative regulation of cell death GO:0060548 345 0.181
neuron projection development GO:0031175 106 0.178
Fly
negative regulation of apoptotic process GO:0043066 316 0.178
regulation of cell motility GO:2000145 299 0.171
intrinsic apoptotic signaling pathway GO:0097193 127 0.163
negative regulation of cellular protein metabolic process GO:0032269 353 0.162
negative regulation of map kinase activity GO:0043407 27 0.158
regulation of cell migration GO:0030334 289 0.145
multicellular organismal aging GO:0010259 3 0.141
Fly
regulation of cellular amine metabolic process GO:0033238 11 0.138
cellular macromolecule catabolic process GO:0044265 380 0.136
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.134
negative regulation of transferase activity GO:0051348 124 0.131
microtubule based movement GO:0007018 32 0.130
vesicle mediated transport GO:0016192 371 0.129
Fly
ribonucleoside triphosphate metabolic process GO:0009199 412 0.127
neuron differentiation GO:0030182 138 0.125
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.124
ras protein signal transduction GO:0007265 73 0.123
gtp catabolic process GO:0006184 237 0.123
lung alveolus development GO:0048286 4 0.122
rho protein signal transduction GO:0007266 26 0.121
positive regulation of cell migration GO:0030335 172 0.120
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.120
negative regulation of stress activated protein kinase signaling cascade GO:0070303 19 0.119
negative regulation of programmed cell death GO:0043069 321 0.118
cellular protein complex assembly GO:0043623 188 0.118
organophosphate catabolic process GO:0046434 430 0.116
actin cytoskeleton organization GO:0030036 207 0.115
Fly
activation of jun kinase activity GO:0007257 7 0.112
Mouse Rat Worm
negative regulation of mapk cascade GO:0043409 56 0.110
chromatin organization GO:0006325 351 0.108
anatomical structure formation involved in morphogenesis GO:0048646 284 0.106
Zebrafish Fly
cell projection organization GO:0030030 252 0.105
Fly
actin filament based process GO:0030029 224 0.103
Fly
negative regulation of intracellular signal transduction GO:1902532 183 0.103
taxis GO:0042330 157 0.100
cell projection morphogenesis GO:0048858 129 0.100
Fly
positive regulation of cell motility GO:2000147 177 0.099
neuron projection morphogenesis GO:0048812 50 0.098
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.097
negative regulation of protein kinase activity GO:0006469 98 0.097
cellular response to oxygen containing compound GO:1901701 276 0.097
Rat
generation of neurons GO:0048699 152 0.096
Fly
negative regulation of kinase activity GO:0033673 106 0.095
guanosine containing compound metabolic process GO:1901068 244 0.095
regulation of locomotion GO:0040012 329 0.094
establishment of vesicle localization GO:0051650 23 0.094
activation of mapkk activity GO:0000186 18 0.094
ubiquitin dependent protein catabolic process GO:0006511 206 0.093
cytoskeleton dependent intracellular transport GO:0030705 21 0.092
peptidyl serine phosphorylation GO:0018105 101 0.090
purine nucleotide catabolic process GO:0006195 405 0.090
defense response GO:0006952 315 0.089
Worm Fly
cellular amine metabolic process GO:0044106 41 0.089
purine nucleoside triphosphate catabolic process GO:0009146 392 0.089
positive regulation of cellular catabolic process GO:0031331 284 0.087
Fly
positive regulation of catabolic process GO:0009896 310 0.087
Fly
histone acetylation GO:0016573 93 0.085
peptidyl serine modification GO:0018209 106 0.085
enzyme linked receptor protein signaling pathway GO:0007167 303 0.082
response to abiotic stimulus GO:0009628 336 0.082
regulation of cytoskeleton organization GO:0051493 177 0.082
regulation of cellular amino acid metabolic process GO:0006521 6 0.082
guanosine containing compound catabolic process GO:1901069 239 0.081
neuron projection regeneration GO:0031102 1 0.081
regulation of cellular ketone metabolic process GO:0010565 50 0.080
melanin metabolic process GO:0006582 1 0.080
Fly
regulation of cell differentiation GO:0045595 393 0.080
Fly
regulation of cellular response to stress GO:0080135 244 0.080
Mouse Rat Worm Fly
gtp metabolic process GO:0046039 239 0.078
microtubule based process GO:0007017 210 0.078
internal peptidyl lysine acetylation GO:0018393 97 0.078
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.077
Mouse Rat Worm Fly
regulation of microtubule cytoskeleton organization GO:0070507 61 0.074
regulation of cellular component movement GO:0051270 334 0.073
organelle localization GO:0051640 84 0.071
regulation of protein localization GO:0032880 296 0.070
regulation of cell cycle GO:0051726 393 0.070
regulation of cellular component biogenesis GO:0044087 281 0.070
viral process GO:0016032 146 0.069
purine ribonucleoside catabolic process GO:0046130 398 0.067
regulation of determination of dorsal identity GO:2000015 2 0.067
protein ubiquitination GO:0016567 314 0.066
positive regulation of determination of dorsal identity GO:2000017 1 0.066
establishment of organelle localization GO:0051656 59 0.066
cell morphogenesis involved in differentiation GO:0000904 144 0.066
Fly
positive regulation of organelle organization GO:0010638 195 0.065
protein acetylation GO:0006473 116 0.065
modification dependent macromolecule catabolic process GO:0043632 212 0.064
regulation of response to external stimulus GO:0032101 222 0.064
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.064
histone modification GO:0016570 251 0.064
axon regeneration GO:0031103 1 0.062
mitotic cell cycle GO:0000278 326 0.062
negative regulation of multicellular organismal process GO:0051241 317 0.061
neurogenesis GO:0022008 169 0.061
Fly
synaptic transmission GO:0007268 61 0.060
oogenesis GO:0048477 2 0.060
Fly
axon transport of mitochondrion GO:0019896 2 0.058
regulation of multi organism process GO:0043900 157 0.056
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.056
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.056
vesicle localization GO:0051648 26 0.055
negative regulation of cell differentiation GO:0045596 171 0.055
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.055
regulation of protein polymerization GO:0032271 63 0.055
locomotory behavior GO:0007626 1 0.054
regulation of cell cycle process GO:0010564 266 0.054
positive regulation of locomotion GO:0040017 186 0.053
morphogenesis of embryonic epithelium GO:0016331 4 0.053
Fly
cell part morphogenesis GO:0032990 137 0.051
Fly
nucleoside triphosphate catabolic process GO:0009143 394 0.051
growth GO:0040007 202 0.051
Fly
regulation of nucleotide metabolic process GO:0006140 269 0.050
positive regulation of cellular component organization GO:0051130 376 0.050
regulation of mitotic cell cycle GO:0007346 189 0.050
response to growth factor GO:0070848 205 0.050
erk1 and erk2 cascade GO:0070371 104 0.050
reactive oxygen species metabolic process GO:0072593 75 0.050
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.050
regulation of axon guidance GO:1902667 3 0.049
cellular response to dna damage stimulus GO:0006974 379 0.048
synaptic vesicle localization GO:0097479 5 0.048
peptidyl lysine modification GO:0018205 144 0.047
cellular protein catabolic process GO:0044257 261 0.047
neuron development GO:0048666 113 0.046
Fly
response to oxygen containing compound GO:1901700 369 0.045
Rat
peptidyl threonine phosphorylation GO:0018107 41 0.044
regulation of protein complex assembly GO:0043254 147 0.044
determination of dorsal ventral asymmetry GO:0048262 4 0.044
ribonucleoside triphosphate catabolic process GO:0009203 391 0.043
system process GO:0003008 349 0.043
immune response GO:0006955 307 0.042
Fly
endocytosis GO:0006897 159 0.042
Fly
axonogenesis GO:0007409 31 0.042
Fly
female gamete generation GO:0007292 2 0.042
Fly
chemotaxis GO:0006935 157 0.042
embryonic epithelial tube formation GO:0001838 4 0.042
positive regulation of protein complex assembly GO:0031334 86 0.041
protein catabolic process GO:0030163 325 0.041
cellular response to hydrogen peroxide GO:0070301 37 0.041
regulation of anatomical structure size GO:0090066 101 0.041
segmentation GO:0035282 4 0.040
Zebrafish
regulation of purine nucleotide metabolic process GO:1900542 264 0.040
positive regulation of dna metabolic process GO:0051054 73 0.039
purine containing compound catabolic process GO:0072523 411 0.039
endosomal transport GO:0016197 129 0.039
regulation of gtpase activity GO:0043087 180 0.039
positive regulation of cellular component biogenesis GO:0044089 158 0.038
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.038
cellular response to nitrogen compound GO:1901699 144 0.038
myoblast fusion GO:0007520 1 0.037
determination of adult lifespan GO:0008340 2 0.037
Fly
lipid metabolic process GO:0006629 381 0.037
mitochondrion organization GO:0007005 156 0.037
establishment of synaptic vesicle localization GO:0097480 5 0.036
determination of dorsal identity GO:0048263 4 0.036
actin filament organization GO:0007015 128 0.035
Fly
peptidyl lysine acetylation GO:0018394 101 0.035
positive regulation of cytoskeleton organization GO:0051495 83 0.035
small gtpase mediated signal transduction GO:0007264 78 0.035
mating GO:0007618 1 0.034
regulation of rho protein signal transduction GO:0035023 79 0.034
nucleoside catabolic process GO:0009164 408 0.034
positive regulation of cellular component movement GO:0051272 181 0.034
modification dependent protein catabolic process GO:0019941 209 0.034
protein maturation GO:0051604 233 0.033
cardiovascular system development GO:0072358 262 0.033
microtubule based transport GO:0010970 21 0.033
receptor metabolic process GO:0043112 81 0.033
positive regulation of cell death GO:0010942 263 0.033
Rat
positive regulation of cellular amine metabolic process GO:0033240 7 0.033
protein modification by small protein conjugation GO:0032446 342 0.033
dna replication GO:0006260 116 0.033
cellular ketone metabolic process GO:0042180 80 0.033
response to hormone GO:0009725 175 0.032
actin filament based movement GO:0030048 17 0.032
cellular response to endogenous stimulus GO:0071495 336 0.032
positive regulation of developmental process GO:0051094 314 0.032
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.032
positive regulation of hydrolase activity GO:0051345 331 0.032
ribonucleotide catabolic process GO:0009261 405 0.031
regulation of ras protein signal transduction GO:0046578 155 0.030
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.030
Fly
positive regulation of response to external stimulus GO:0032103 88 0.030
specification of organ identity GO:0010092 3 0.030
programmed necrotic cell death GO:0097300 18 0.030
regulation of binding GO:0051098 111 0.030
cellular amino acid metabolic process GO:0006520 116 0.029
blastoderm segmentation GO:0007350 2 0.029
negative regulation of organelle organization GO:0010639 126 0.029
motor neuron axon guidance GO:0008045 2 0.029
epithelium development GO:0060429 227 0.029
Zebrafish Fly
proteasomal protein catabolic process GO:0010498 176 0.029
negative regulation of cellular component organization GO:0051129 235 0.028
heart development GO:0007507 95 0.028
regulation of viral transcription GO:0046782 34 0.028
dephosphorylation GO:0016311 209 0.028
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.028
response to external biotic stimulus GO:0043207 261 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.028
i kappab kinase nf kappab signaling GO:0007249 166 0.028
positive regulation of programmed cell death GO:0043068 249 0.028
Rat
regulation of erk1 and erk2 cascade GO:0070372 99 0.028
glycosyl compound catabolic process GO:1901658 413 0.027
positive regulation of immune system process GO:0002684 283 0.027
interspecies interaction between organisms GO:0044419 156 0.027
regulation of cell growth GO:0001558 135 0.027
regulation of defense response GO:0031347 154 0.027
digestive system development GO:0055123 75 0.027
regulation of small gtpase mediated signal transduction GO:0051056 156 0.027
apoptotic mitochondrial changes GO:0008637 57 0.027
syncytium formation by plasma membrane fusion GO:0000768 2 0.027
necrotic cell death GO:0070265 21 0.026
tube morphogenesis GO:0035239 95 0.026
regeneration GO:0031099 4 0.026
protein localization to membrane GO:0072657 160 0.026
single organism cellular localization GO:1902580 332 0.026
cellular response to metal ion GO:0071248 43 0.026
Fly
organic hydroxy compound metabolic process GO:1901615 147 0.026
Fly
actin filament bundle assembly GO:0051017 54 0.025
Fly
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.025
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.025
regulation of chromatin organization GO:1902275 56 0.025
negative regulation of protein processing GO:0010955 142 0.025
regulation of vesicle mediated transport GO:0060627 130 0.025
regulation of nucleoside metabolic process GO:0009118 209 0.024
regulation of neurogenesis GO:0050767 82 0.024
response to axon injury GO:0048678 1 0.024
nucleoside phosphate catabolic process GO:1901292 412 0.024
negative regulation of cell cycle GO:0045786 193 0.024
peripheral nervous system development GO:0007422 2 0.024
tube development GO:0035295 125 0.024
retrograde transport endosome to golgi GO:0042147 45 0.024
cellular response to external stimulus GO:0071496 111 0.024
Human
regulation of axon extension involved in axon guidance GO:0048841 2 0.024
dna repair GO:0006281 198 0.024
regulation of gtp catabolic process GO:0033124 180 0.023
response to light stimulus GO:0009416 87 0.023
biological adhesion GO:0022610 331 0.023
multicellular organismal response to stress GO:0033555 1 0.023
response to hydrogen peroxide GO:0042542 40 0.023
regulation of anatomical structure morphogenesis GO:0022603 286 0.023
response to biotic stimulus GO:0009607 276 0.023
associative learning GO:0008306 1 0.023
actin filament bundle organization GO:0061572 54 0.023
Fly
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.023
cellular response to mechanical stimulus GO:0071260 39 0.023
Human
ossification GO:0001503 121 0.023
regulation of viral process GO:0050792 103 0.023
amine metabolic process GO:0009308 44 0.023
positive regulation of gtpase activity GO:0043547 166 0.022
microtubule cytoskeleton organization GO:0000226 176 0.022
organ formation GO:0048645 3 0.022
somatic stem cell maintenance GO:0035019 4 0.022
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.022
protein acylation GO:0043543 138 0.022
regulation of chromosome organization GO:0033044 103 0.022
positive regulation of nucleotide catabolic process GO:0030813 185 0.022
protein oligomerization GO:0051259 173 0.022
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.022
inflammatory response GO:0006954 79 0.022
positive regulation of nucleoside metabolic process GO:0045979 186 0.022
regulation of growth GO:0040008 165 0.022
engulfment of apoptotic cell GO:0043652 2 0.022
Fly
cell growth GO:0016049 160 0.022
Fly
positive regulation of axon extension GO:0045773 4 0.021
negative regulation of binding GO:0051100 57 0.021
cytokine production GO:0001816 247 0.021
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.021
tripartite regional subdivision GO:0007351 2 0.021
positive regulation of rho protein signal transduction GO:0035025 4 0.021
regulation of protein catabolic process GO:0042176 155 0.021
negative regulation of response to external stimulus GO:0032102 83 0.021
positive regulation of nucleotide metabolic process GO:0045981 230 0.021
axon development GO:0061564 34 0.021
Fly
axon extension GO:0048675 13 0.021
Fly
neuromuscular junction development GO:0007528 3 0.021
release of cytochrome c from mitochondria GO:0001836 35 0.021
regulation of cytokine production GO:0001817 232 0.020
single organism membrane organization GO:0044802 268 0.020
response to nitrogen compound GO:1901698 184 0.020
regulation of proteolysis GO:0030162 293 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.020
positive regulation of cell proliferation GO:0008284 301 0.020
nucleotide catabolic process GO:0009166 408 0.020
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
regulation of synaptic plasticity GO:0048167 3 0.020
positive regulation of gtp catabolic process GO:0033126 166 0.020
regulation of cellular component size GO:0032535 82 0.020
respiratory gaseous exchange GO:0007585 3 0.020
positive regulation of multi organism process GO:0043902 56 0.020
somatic muscle development GO:0007525 1 0.020
cytoplasmic transport GO:0016482 379 0.020
anterior posterior axis specification embryo GO:0008595 2 0.019
chromosome segregation GO:0007059 114 0.019
nucleocytoplasmic transport GO:0006913 176 0.019
cell fate determination GO:0001709 3 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.019
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.019
microtubule polymerization or depolymerization GO:0031109 37 0.019
positive regulation of apoptotic process GO:0043065 246 0.019
Rat
cellular response to reactive nitrogen species GO:1902170 2 0.019
regulation of protein transport GO:0051223 213 0.019
viral life cycle GO:0019058 132 0.019
response to inorganic substance GO:0010035 127 0.018
Fly
negative regulation of apoptotic signaling pathway GO:2001234 97 0.018
dna conformation change GO:0071103 113 0.018
negative regulation of developmental process GO:0051093 247 0.018
endodermal cell fate specification GO:0001714 4 0.018
long term memory GO:0007616 2 0.018
cell cycle phase transition GO:0044770 173 0.018
head development GO:0060322 108 0.018
membrane organization GO:0061024 292 0.018
Fly
posttranscriptional regulation of gene expression GO:0010608 213 0.018
oocyte development GO:0048599 1 0.018
oocyte differentiation GO:0009994 2 0.018
neurotransmitter secretion GO:0007269 4 0.018
regulation of peptidase activity GO:0052547 180 0.018
positive regulation of transport GO:0051050 336 0.018
actin filament polymerization GO:0030041 45 0.018
fear response GO:0042596 0 0.018
cell adhesion GO:0007155 325 0.018
peptidyl tyrosine modification GO:0018212 170 0.018
protein polymerization GO:0051258 71 0.018
transmembrane transport GO:0055085 399 0.017
mrna metabolic process GO:0016071 175 0.017
organonitrogen compound biosynthetic process GO:1901566 200 0.017
digestive tract morphogenesis GO:0048546 56 0.017
response to organonitrogen compound GO:0010243 156 0.017
mrna processing GO:0006397 133 0.017
internal protein amino acid acetylation GO:0006475 101 0.017
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 3 0.017
memory GO:0007613 3 0.017
multi organism metabolic process GO:0044033 41 0.017
double strand break repair GO:0006302 101 0.017
innate immune response GO:0045087 178 0.017
Fly
regulation of cell cycle phase transition GO:1901987 126 0.017
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
multi organism cellular process GO:0044764 156 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
rna processing GO:0006396 255 0.016
histone h4 acetylation GO:0043967 47 0.016
anterior posterior axis specification GO:0009948 2 0.016
tissue morphogenesis GO:0048729 96 0.016
Fly
muscle tissue development GO:0060537 62 0.016
circulatory system development GO:0072359 262 0.016
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.016
protein modification by small protein removal GO:0070646 92 0.016
regulation of neurotransmitter secretion GO:0046928 3 0.016
rhythmic behavior GO:0007622 2 0.016
neuron projection extension GO:1990138 14 0.016
Fly
nucleoside triphosphate metabolic process GO:0009141 422 0.016
positive regulation of dna replication GO:0045740 35 0.016
behavioral defense response GO:0002209 0 0.016
central nervous system development GO:0007417 123 0.016
regulation of synaptic vesicle exocytosis GO:2000300 2 0.016
regulation of cell adhesion GO:0030155 166 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.016
establishment of protein localization to organelle GO:0072594 172 0.016
regulation of reactive oxygen species metabolic process GO:2000377 41 0.016
embryo development GO:0009790 123 0.016
Zebrafish Fly
regulation of actin cytoskeleton organization GO:0032956 116 0.016
positive regulation of protein polymerization GO:0032273 45 0.016
spermatid differentiation GO:0048515 4 0.016
forebrain development GO:0030900 26 0.016
alcohol metabolic process GO:0006066 114 0.015
methylation GO:0032259 106 0.015
regulation of transmembrane transporter activity GO:0022898 74 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
organelle fission GO:0048285 149 0.015
protein polyubiquitination GO:0000209 110 0.015
ion homeostasis GO:0050801 230 0.015
regulation of protein ubiquitination GO:0031396 95 0.015
ribonucleoside catabolic process GO:0042454 406 0.015
pattern specification process GO:0007389 43 0.015
Zebrafish Fly
g protein coupled receptor signaling pathway GO:0007186 207 0.015
embryonic digestive tract morphogenesis GO:0048557 2 0.015
rab protein signal transduction GO:0032482 4 0.015
positive regulation of cell development GO:0010720 92 0.015
ectodermal digestive tract morphogenesis GO:0048567 1 0.015
eyelid development in camera type eye GO:0061029 2 0.015
macromolecule methylation GO:0043414 97 0.015
reactive nitrogen species metabolic process GO:2001057 3 0.015
regulation of cell morphogenesis GO:0022604 153 0.015
epithelium migration GO:0090132 119 0.015
Fly
leukocyte activation GO:0045321 164 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
mitotic cell cycle phase transition GO:0044772 162 0.014
regulation of protein maturation GO:1903317 150 0.014
regulation of actin filament length GO:0030832 56 0.014
regulation of synapse structure and activity GO:0050803 7 0.014
spermatid development GO:0007286 4 0.014
negative regulation of immune system process GO:0002683 136 0.014
protein methylation GO:0006479 74 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
receptor internalization GO:0031623 43 0.014
regulation of interleukin 6 production GO:0032675 37 0.014
regulation of dna metabolic process GO:0051052 153 0.014
protein deacylation GO:0035601 39 0.014
t cell differentiation in thymus GO:0033077 4 0.014
cellular response to abiotic stimulus GO:0071214 117 0.014
Human
single organism carbohydrate metabolic process GO:0044723 193 0.014
protein alkylation GO:0008213 74 0.014
rna interference GO:0016246 4 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
actin polymerization or depolymerization GO:0008154 56 0.014
negative regulation of cell cycle process GO:0010948 121 0.014
endomembrane system organization GO:0010256 196 0.014
regulation of synaptic vesicle transport GO:1902803 3 0.014
histone methylation GO:0016571 60 0.014
positive regulation of apoptotic signaling pathway GO:2001235 70 0.014
cellular response to biotic stimulus GO:0071216 71 0.014

MAP2K7 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.843
acquired metabolic disease DOID:0060158 58 0.713
diabetes mellitus DOID:9351 31 0.634
carbohydrate metabolism disease DOID:0050013 32 0.634
glucose metabolism disease DOID:4194 32 0.634
type 2 diabetes mellitus DOID:9352 28 0.334
chromosomal disease DOID:0080014 16 0.099
immune system disease DOID:2914 155 0.021
gonadal dysgenesis DOID:14447 8 0.021
artery disease DOID:0050828 23 0.021
vascular disease DOID:178 25 0.021
cardiovascular system disease DOID:1287 106 0.021
inherited metabolic disorder DOID:655 242 0.020
disease of cellular proliferation DOID:14566 174 0.018
musculoskeletal system disease DOID:17 223 0.016
central nervous system disease DOID:331 186 0.014
nervous system disease DOID:863 431 0.014
connective tissue disease DOID:65 109 0.014
neurodegenerative disease DOID:1289 102 0.014
brain disease DOID:936 73 0.014