|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.967
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.895
|
Mouse Rat |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.830
|
Mouse Rat |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.793
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.733
|
Mouse Rat |
|
|
hippo signaling
|
GO:0035329 |
20 |
0.727
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.712
|
Rat |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.694
|
|
|
|
determination of dorsal identity
|
GO:0048263 |
4 |
0.679
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.678
|
Mouse Rat |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.643
|
Mouse Rat |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.612
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.578
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.574
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.563
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.559
|
Mouse Rat |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.546
|
Mouse Rat |
|
|
growth
|
GO:0040007 |
202 |
0.528
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.511
|
Mouse Rat |
|
|
cell development
|
GO:0048468 |
328 |
0.508
|
Mouse |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.505
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.505
|
Mouse Rat |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.499
|
Rat |
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.497
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.493
|
Mouse Rat |
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.486
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.485
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.465
|
Mouse Rat |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.464
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.456
|
Mouse |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.454
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.448
|
Mouse |
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.442
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.437
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.436
|
Mouse Rat |
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.432
|
Mouse Rat |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.432
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
7 |
0.425
|
Mouse Rat |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.419
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.413
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.406
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.402
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.402
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.399
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.388
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.385
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.382
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.377
|
Mouse Rat |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.374
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.374
|
Mouse Rat |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.373
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.371
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.370
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.366
|
Mouse |
|
|
response to radiation
|
GO:0009314 |
151 |
0.362
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.359
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.354
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.353
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.347
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.347
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.346
|
Mouse Rat |
|
|
negative regulation of phagocytosis engulfment
|
GO:0060101 |
1 |
0.345
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.344
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.341
|
Mouse |
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.335
|
Mouse Rat |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.332
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.329
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.321
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.319
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.316
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.314
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.314
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.312
|
|
|
|
jun phosphorylation
|
GO:0007258 |
28 |
0.307
|
Mouse Rat |
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.305
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.304
|
Mouse |
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.298
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
3 |
0.295
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.288
|
Rat |
|
|
axon extension
|
GO:0048675 |
13 |
0.275
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.275
|
Mouse Rat |
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.272
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.270
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.262
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.261
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.260
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.259
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.248
|
Rat |
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.248
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.247
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.242
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.240
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.239
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.239
|
Mouse Rat |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.237
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.235
|
|
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.235
|
|
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
2 |
0.228
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.226
|
Rat |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.218
|
Mouse Rat |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.215
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.214
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.214
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.212
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.210
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.203
|
Mouse |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.203
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.197
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.196
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.196
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.194
|
Mouse Rat |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.193
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.193
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.192
|
Rat |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.190
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.188
|
Mouse Rat |
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.186
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.185
|
Mouse Rat |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.184
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.182
|
|
|
|
cellular response to heat
|
GO:0034605 |
14 |
0.182
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.181
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.178
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.177
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.177
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.176
|
|
|
|
regulation of developmental pigmentation
|
GO:0048070 |
2 |
0.175
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.174
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.171
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.171
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.168
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.167
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.166
|
Mouse |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.163
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.163
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.162
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.160
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.159
|
Rat |
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.157
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.156
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.154
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.153
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.151
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.151
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.150
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.149
|
Rat |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.145
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.145
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.144
|
Mouse Rat |
|
|
response to uv
|
GO:0009411 |
73 |
0.142
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.139
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.138
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.136
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.134
|
Rat |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.133
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.132
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.131
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.130
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.129
|
Rat |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.129
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.127
|
|
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.126
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.126
|
|
|
|
response to heat
|
GO:0009408 |
21 |
0.126
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.125
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.121
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.121
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.121
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.120
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.118
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.117
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.117
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.117
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.116
|
Mouse |
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.116
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.116
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.114
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.114
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.114
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.113
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.113
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.113
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway by arrestin
|
GO:0002032 |
2 |
0.112
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.112
|
|
|
|
vesicle transport along actin filament
|
GO:0030050 |
2 |
0.111
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.111
|
|
|
|
system process
|
GO:0003008 |
349 |
0.110
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.109
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.108
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.108
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.107
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.106
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.105
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.104
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.103
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.103
|
Mouse Rat |
|
|
autophagy
|
GO:0006914 |
88 |
0.103
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.102
|
Mouse Rat |
|
|
dna replication
|
GO:0006260 |
116 |
0.102
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.102
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.101
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
41 |
0.101
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.099
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.097
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.097
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.097
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.096
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.096
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.096
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.096
|
Mouse Rat |
|
|
immune system development
|
GO:0002520 |
195 |
0.096
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.095
|
|
|
|
aging
|
GO:0007568 |
66 |
0.094
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.092
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.091
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.091
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.091
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.091
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.089
|
Rat |
|
|
protein targeting
|
GO:0006605 |
187 |
0.088
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.088
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.088
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.087
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.087
|
Mouse |
|
|
immune response
|
GO:0006955 |
307 |
0.087
|
|
|
|
activation of jnkk activity
|
GO:0007256 |
1 |
0.086
|
Rat |
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.086
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.086
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.085
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.083
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.082
|
Rat |
|
|
anion transport
|
GO:0006820 |
161 |
0.082
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.082
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.082
|
Mouse Rat |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.081
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.081
|
Mouse Rat |
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.080
|
|
|
|
establishment of protein localization to mitochondrion
|
GO:0072655 |
22 |
0.080
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.079
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.079
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.078
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.078
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
2 |
0.078
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.078
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.078
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.077
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.077
|
Mouse |
|
|
digestive system development
|
GO:0055123 |
75 |
0.076
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.076
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.076
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.075
|
Rat |
|
|
secretion
|
GO:0046903 |
254 |
0.074
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.072
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.072
|
Mouse |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.071
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.070
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.070
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.070
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.070
|
Mouse |
|
|
ectodermal digestive tract development
|
GO:0007439 |
1 |
0.069
|
|
|
|
phagocytosis engulfment
|
GO:0006911 |
7 |
0.069
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.069
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.069
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.069
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.068
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.068
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.068
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.068
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.067
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.066
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.066
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.066
|
|
|
|
retina layer formation
|
GO:0010842 |
3 |
0.066
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.065
|
Rat |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.065
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.064
|
|
|
|
basement membrane organization
|
GO:0071711 |
3 |
0.064
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.063
|
|
|
|
protein folding
|
GO:0006457 |
38 |
0.063
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.063
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.063
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.062
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.062
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.062
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.062
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.061
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.061
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.061
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.061
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
24 |
0.060
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.060
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.060
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.059
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.059
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.059
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.059
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.059
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.058
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.058
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.057
|
Rat |
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.057
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.057
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.057
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.056
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.056
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.056
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.056
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.056
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.056
|
|
|
|
response to osmotic stress
|
GO:0006970 |
17 |
0.056
|
Rat |
|
|
secondary metabolic process
|
GO:0019748 |
17 |
0.056
|
|
|
|
apoptotic cell clearance
|
GO:0043277 |
12 |
0.055
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.055
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.055
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.055
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.055
|
Mouse Rat |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.055
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.054
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.054
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.054
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.053
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.053
|
Mouse Rat |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.053
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.052
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.051
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.051
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.050
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.050
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.050
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.050
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.050
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.050
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.050
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.050
|
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.049
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.049
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.049
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.049
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.049
|
|
|
|
positive regulation of organic acid transport
|
GO:0032892 |
3 |
0.049
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.049
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.049
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.048
|
Mouse Rat |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.048
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.048
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.048
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.048
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.046
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.046
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.046
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.046
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.046
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.046
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.046
|
Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.046
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.045
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.045
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.045
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.044
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.044
|
|
|
|
muscle hypertrophy
|
GO:0014896 |
14 |
0.044
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.044
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.044
|
|
|
|
regulation of synaptic transmission dopaminergic
|
GO:0032225 |
4 |
0.044
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.043
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.043
|
Mouse |
|
|
positive regulation of rho protein signal transduction
|
GO:0035025 |
4 |
0.043
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.042
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.042
|
|
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
12 |
0.042
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.042
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.042
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.042
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.041
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.041
|
Mouse Rat |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.041
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.041
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.040
|
Rat |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.040
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.040
|
Mouse Rat |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.040
|
Mouse |
|
|
memory
|
GO:0007613 |
3 |
0.040
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.040
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.040
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.040
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.040
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.040
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.040
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.039
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.039
|
Rat |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.039
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.039
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
24 |
0.038
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.038
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.038
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.038
|
Mouse |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.038
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.038
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.038
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.037
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.037
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.037
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.037
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.037
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.037
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.037
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
9 |
0.037
|
|
|
|
regulation of rac gtpase activity
|
GO:0032314 |
4 |
0.036
|
|
|
|
rna splicing via transesterification reactions with bulged adenosine as nucleophile
|
GO:0000377 |
89 |
0.036
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.036
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.036
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.036
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.036
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.036
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.036
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.035
|
|
|
|
embryonic digestive tract development
|
GO:0048566 |
10 |
0.035
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.035
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.035
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.035
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.035
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.034
|
|
|
|
striated muscle hypertrophy
|
GO:0014897 |
14 |
0.034
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.034
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.034
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.034
|
Mouse Rat |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.034
|
|
|
|
positive regulation of determination of dorsal identity
|
GO:2000017 |
1 |
0.033
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.033
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.033
|
Mouse |
|
|
pigment metabolic process
|
GO:0042440 |
16 |
0.033
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.033
|
|
|
|
melanocyte differentiation
|
GO:0030318 |
2 |
0.033
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.033
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.033
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.033
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.033
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.033
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.033
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.033
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.032
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.032
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.032
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.032
|
|
|
|
phagocytosis
|
GO:0006909 |
42 |
0.032
|
|
|
|
regulation of hippo signaling
|
GO:0035330 |
8 |
0.032
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.032
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.032
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.032
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.032
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.032
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.032
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.032
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.032
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.032
|
|
|
|
prostaglandin secretion
|
GO:0032310 |
2 |
0.032
|
|
|
|
multicellular organismal movement
|
GO:0050879 |
17 |
0.032
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.032
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.031
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
12 |
0.031
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.031
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.031
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.031
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.031
|
Mouse Rat |
|
|
posttranscriptional gene silencing
|
GO:0016441 |
25 |
0.031
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.031
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.031
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.031
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.031
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.031
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.030
|
|
|
|
positive regulation of fatty acid transport
|
GO:2000193 |
3 |
0.030
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.030
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.030
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.030
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.030
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.030
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.030
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.030
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.030
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.030
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.030
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.030
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.029
|
|
|
|
heart growth
|
GO:0060419 |
6 |
0.029
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.029
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.029
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.029
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.029
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.029
|
|
