Homo sapiens

103 known processes

MAP3K11

mitogen-activated protein kinase kinase kinase 11

(Aliases: PTK1,MGC17114,MEKK11,MLK3,MLK-3,SPRK)

MAP3K11 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
peptidyl serine phosphorylation GO:0018105 101 0.999
Human
behavioral response to ethanol GO:0048149 2 0.984
positive regulation of protein phosphorylation GO:0001934 313 0.981
endomembrane system organization GO:0010256 196 0.961
positive regulation of phosphorylation GO:0042327 394 0.953
activation of protein kinase activity GO:0032147 90 0.951
cellular response to hormone stimulus GO:0032870 125 0.950
peptidyl serine modification GO:0018209 106 0.944
Human
regulation of jun kinase activity GO:0043506 27 0.942
positive regulation of jun kinase activity GO:0043507 23 0.931
golgi organization GO:0007030 38 0.923
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.905
positive regulation of stress activated mapk cascade GO:0032874 60 0.889
cellular response to peptide hormone stimulus GO:0071375 56 0.887
regulation of cellular response to stress GO:0080135 244 0.878
regulation of protein serine threonine kinase activity GO:0071900 179 0.864
regulation of growth rate GO:0040009 1 0.853
positive regulation of tor signaling GO:0032008 11 0.843
cellular response to endogenous stimulus GO:0071495 336 0.826
regulation of tor signaling GO:0032006 30 0.825
regulation of cellular component size GO:0032535 82 0.817
regulation of protein kinase activity GO:0045859 289 0.801
regulation of map kinase activity GO:0043405 108 0.779
tor signaling GO:0031929 39 0.776
positive regulation of kinase activity GO:0033674 204 0.768
positive regulation of mapk cascade GO:0043410 190 0.707
response to abiotic stimulus GO:0009628 336 0.672
Fly
positive regulation of cellular component organization GO:0051130 376 0.649
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.635
response to nitrogen compound GO:1901698 184 0.633
cellular response to organonitrogen compound GO:0071417 124 0.632
cellular response to insulin stimulus GO:0032869 41 0.620
cellular response to peptide GO:1901653 59 0.617
regulation of cellular response to insulin stimulus GO:1900076 17 0.612
response to hormone GO:0009725 175 0.607
regulation of stress activated mapk cascade GO:0032872 84 0.593
regulation of jnk cascade GO:0046328 73 0.587
regulation of cellular ketone metabolic process GO:0010565 50 0.585
positive regulation of programmed cell death GO:0043068 249 0.581
Rat
response to cytokine GO:0034097 232 0.576
cellular response to nitrogen compound GO:1901699 144 0.575
rho protein signal transduction GO:0007266 26 0.557
cellular amine metabolic process GO:0044106 41 0.548
response to organonitrogen compound GO:0010243 156 0.534
positive regulation of ras gtpase activity GO:0032320 117 0.534
enzyme linked receptor protein signaling pathway GO:0007167 303 0.531
positive regulation of transferase activity GO:0051347 227 0.524
response to insulin GO:0032868 45 0.518
cellular response to oxygen containing compound GO:1901701 276 0.514
Fly
positive regulation of map kinase activity GO:0043406 80 0.510
positive regulation of actin filament polymerization GO:0030838 38 0.484
regulation of anatomical structure size GO:0090066 101 0.471
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.471
response to oxygen containing compound GO:1901700 369 0.463
Fly
positive regulation of rho gtpase activity GO:0032321 56 0.456
insulin receptor signaling pathway GO:0008286 23 0.455
regulation of actin filament polymerization GO:0030833 50 0.455
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.449
response to peptide GO:1901652 65 0.435
regulation of gtpase activity GO:0043087 180 0.422
gtp metabolic process GO:0046039 239 0.419
regulation of cellular component biogenesis GO:0044087 281 0.410
regulation of insulin receptor signaling pathway GO:0046626 13 0.405
regulation of mapk cascade GO:0043408 262 0.403
regulation of protein polymerization GO:0032271 63 0.385
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.385
regulation of nucleoside metabolic process GO:0009118 209 0.380
regulation of protein complex assembly GO:0043254 147 0.376
regulation of transferase activity GO:0051338 355 0.369
small gtpase mediated signal transduction GO:0007264 78 0.358
lipid homeostasis GO:0055088 39 0.347
organophosphate catabolic process GO:0046434 430 0.342
triglyceride homeostasis GO:0070328 14 0.336
purine nucleoside triphosphate metabolic process GO:0009144 412 0.335
jnk cascade GO:0007254 80 0.329
mapk cascade GO:0000165 288 0.328
regulation of small gtpase mediated signal transduction GO:0051056 156 0.326
positive regulation of cell death GO:0010942 263 0.320
Rat
ribonucleoside triphosphate metabolic process GO:0009199 412 0.316
response to peptide hormone GO:0043434 61 0.313
acylglycerol homeostasis GO:0055090 14 0.313
nucleoside triphosphate catabolic process GO:0009143 394 0.311
actin cytoskeleton organization GO:0030036 207 0.307
purine ribonucleotide catabolic process GO:0009154 404 0.306
growth GO:0040007 202 0.305
Fly
regulation of actin polymerization or depolymerization GO:0008064 56 0.302
stress activated protein kinase signaling cascade GO:0031098 94 0.297
positive regulation of gtpase activity GO:0043547 166 0.296
regulation of rho protein signal transduction GO:0035023 79 0.295
membrane organization GO:0061024 292 0.288
post embryonic development GO:0009791 2 0.282
Fly
positive regulation of nucleoside metabolic process GO:0045979 186 0.278
positive regulation of organelle organization GO:0010638 195 0.277
positive regulation of cellular component biogenesis GO:0044089 158 0.271
gtp catabolic process GO:0006184 237 0.265
regulation of nucleotide catabolic process GO:0030811 205 0.263
regulation of ras protein signal transduction GO:0046578 155 0.261
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.260
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.256
cell development GO:0048468 328 0.255
Fly
positive regulation of protein polymerization GO:0032273 45 0.251
regulation of cell adhesion GO:0030155 166 0.241
cell morphogenesis GO:0000902 296 0.238
Fly
nucleoside triphosphate metabolic process GO:0009141 422 0.229
purine nucleoside catabolic process GO:0006152 398 0.228
nervous system development GO:0007399 293 0.219
ras protein signal transduction GO:0007265 73 0.216
regulation of cytoskeleton organization GO:0051493 177 0.215
positive regulation of nucleotide metabolic process GO:0045981 230 0.210
actin filament organization GO:0007015 128 0.209
signal transduction by phosphorylation GO:0023014 297 0.204
positive regulation of protein complex assembly GO:0031334 86 0.204
response to uv GO:0009411 73 0.195
response to tumor necrosis factor GO:0034612 76 0.191
amine metabolic process GO:0009308 44 0.189
cellular component morphogenesis GO:0032989 314 0.187
Fly
behavior GO:0007610 112 0.187
regulation of kinase activity GO:0043549 314 0.184
neuromuscular junction development GO:0007528 3 0.184
cellular macromolecular complex assembly GO:0034622 324 0.178
positive regulation of apoptotic process GO:0043065 246 0.171
Rat
response to alcohol GO:0097305 64 0.165
Fly
glycosyl compound catabolic process GO:1901658 413 0.163
regulation of purine nucleotide catabolic process GO:0033121 205 0.163
regulation of purine nucleotide metabolic process GO:1900542 264 0.163
actin polymerization or depolymerization GO:0008154 56 0.159
regulation of nucleotide metabolic process GO:0006140 269 0.158
cell projection organization GO:0030030 252 0.152
positive regulation of hydrolase activity GO:0051345 331 0.150
regulation of rho gtpase activity GO:0032319 66 0.150
regulation of cell cell adhesion mediated by cadherin GO:2000047 4 0.142
negative regulation of multicellular organismal process GO:0051241 317 0.139
spermatid differentiation GO:0048515 4 0.133
response to radiation GO:0009314 151 0.131
purine ribonucleoside catabolic process GO:0046130 398 0.127
vacuole organization GO:0007033 44 0.124
positive regulation of cytoskeleton organization GO:0051495 83 0.124
positive regulation of cellular amine metabolic process GO:0033240 7 0.123
regulation of growth GO:0040008 165 0.122
negative regulation of cellular component organization GO:0051129 235 0.121
cellular ketone metabolic process GO:0042180 80 0.117
locomotory behavior GO:0007626 1 0.115
actin filament polymerization GO:0030041 45 0.112
nucleoside phosphate catabolic process GO:1901292 412 0.112
regulation of cell substrate adhesion GO:0010810 68 0.112
positive regulation of cellular catabolic process GO:0031331 284 0.111
guanosine containing compound catabolic process GO:1901069 239 0.111
positive regulation of rac gtpase activity GO:0032855 31 0.110
adult behavior GO:0030534 18 0.109
ribonucleoside triphosphate catabolic process GO:0009203 391 0.109
purine nucleoside triphosphate catabolic process GO:0009146 392 0.106
cell adhesion GO:0007155 325 0.103
ribonucleotide catabolic process GO:0009261 405 0.101
regulation of cell matrix adhesion GO:0001952 42 0.101
regulation of actin cytoskeleton organization GO:0032956 116 0.100
regulation of ras gtpase activity GO:0032318 128 0.099
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.098
regulation of cell differentiation GO:0045595 393 0.098
regulation of cell projection organization GO:0031344 107 0.097
regulation of cell cycle GO:0051726 393 0.097
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.097
positive regulation of actin filament bundle assembly GO:0032233 25 0.097
single organismal cell cell adhesion GO:0016337 148 0.096
regulation of actin filament length GO:0030832 56 0.092
positive regulation of catabolic process GO:0009896 310 0.091
purine ribonucleoside metabolic process GO:0046128 437 0.091
positive regulation of cell motility GO:2000147 177 0.089
positive regulation of nucleotide catabolic process GO:0030813 185 0.087
segmentation GO:0035282 4 0.082
regulation of actin filament based process GO:0032970 141 0.082
regulation of response to external stimulus GO:0032101 222 0.080
single organism cellular localization GO:1902580 332 0.080
guanosine containing compound metabolic process GO:1901068 244 0.075
chromatin modification GO:0016568 298 0.074
negative regulation of phosphate metabolic process GO:0045936 267 0.074
regulation of microtubule based process GO:0032886 74 0.073
multicellular organismal aging GO:0010259 3 0.071
erbb signaling pathway GO:0038127 44 0.070
positive regulation of jnk cascade GO:0046330 52 0.069
neural tube formation GO:0001841 3 0.067
apoptotic signaling pathway GO:0097190 268 0.067
negative regulation of phosphorus metabolic process GO:0010563 267 0.067
protein targeting to nucleus GO:0044744 104 0.066
response to light stimulus GO:0009416 87 0.066
single organism cell adhesion GO:0098602 179 0.066
leukocyte migration GO:0050900 107 0.065
positive regulation of cell projection organization GO:0031346 64 0.065
nucleoside catabolic process GO:0009164 408 0.065
stress activated mapk cascade GO:0051403 93 0.064
cell matrix adhesion GO:0007160 85 0.063
vesicle organization GO:0016050 62 0.063
negative regulation of catalytic activity GO:0043086 335 0.062
brain development GO:0007420 97 0.062
microtubule based process GO:0007017 210 0.062
protein modification by small protein conjugation GO:0032446 342 0.062
regulation of protein localization GO:0032880 296 0.061
regulation of microtubule cytoskeleton organization GO:0070507 61 0.061
neuron projection development GO:0031175 106 0.061
establishment of organelle localization GO:0051656 59 0.060
single organism membrane organization GO:0044802 268 0.060
biological adhesion GO:0022610 331 0.058
determination of adult lifespan GO:0008340 2 0.058
protein polymerization GO:0051258 71 0.058
protein localization to organelle GO:0033365 280 0.057
microtubule cytoskeleton organization GO:0000226 176 0.055
regulation of cytokine production GO:0001817 232 0.055
actin filament bundle organization GO:0061572 54 0.053
actin nucleation GO:0045010 21 0.052
negative regulation of apoptotic process GO:0043066 316 0.052
nucleotide catabolic process GO:0009166 408 0.052
peptidyl tyrosine phosphorylation GO:0018108 170 0.052
defense response GO:0006952 315 0.052
chromatin organization GO:0006325 351 0.052
activation of jun kinase activity GO:0007257 7 0.051
regulation of stress fiber assembly GO:0051492 32 0.051
negative regulation of protein phosphorylation GO:0001933 140 0.051
purine nucleotide catabolic process GO:0006195 405 0.051
positive regulation of locomotion GO:0040017 186 0.050
positive regulation of cell substrate adhesion GO:0010811 37 0.050
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 11 0.050
response to other organism GO:0051707 261 0.050
compound eye development GO:0048749 1 0.050
chemical homeostasis GO:0048878 306 0.049
anatomical structure formation involved in morphogenesis GO:0048646 284 0.049
Fly
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.049
cellular amino acid metabolic process GO:0006520 116 0.049
regulation of cell projection assembly GO:0060491 47 0.048
negative regulation of cell proliferation GO:0008285 228 0.048
negative regulation of cell death GO:0060548 345 0.047
protein autophosphorylation GO:0046777 123 0.047
positive regulation of protein kinase activity GO:0045860 190 0.047
cell projection assembly GO:0030031 126 0.047
regulation of cellular amino acid metabolic process GO:0006521 6 0.046
endocytosis GO:0006897 159 0.045
embryonic epithelial tube formation GO:0001838 4 0.045
regulation of cell cycle process GO:0010564 266 0.044
actin filament based process GO:0030029 224 0.044
regulation of gtp catabolic process GO:0033124 180 0.044
protein targeting GO:0006605 187 0.043
head development GO:0060322 108 0.042
positive regulation of cellular component movement GO:0051272 181 0.042
cellular protein complex assembly GO:0043623 188 0.041
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.041
regulation of cellular component movement GO:0051270 334 0.041
generation of neurons GO:0048699 152 0.041
actin filament bundle assembly GO:0051017 54 0.040
response to bacterium GO:0009617 144 0.040
purine containing compound catabolic process GO:0072523 411 0.039
regulation of erbb signaling pathway GO:1901184 27 0.039
central nervous system development GO:0007417 123 0.039
positive regulation of cell division GO:0051781 59 0.038
regulation of peptidyl serine phosphorylation GO:0033135 50 0.038
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.038
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.037
embryo development GO:0009790 123 0.037
Fly
establishment of vesicle localization GO:0051650 23 0.037
cell substrate junction assembly GO:0007044 35 0.037
negative regulation of protein complex assembly GO:0031333 43 0.037
memory GO:0007613 3 0.037
chromosome segregation GO:0007059 114 0.037
regulation of protein targeting GO:1903533 91 0.037
protein localization to membrane GO:0072657 160 0.036
negative regulation of phosphorylation GO:0042326 174 0.036
cell cell adhesion mediated by cadherin GO:0044331 4 0.036
positive regulation of developmental process GO:0051094 314 0.036
regulation of locomotion GO:0040012 329 0.035
epithelial cell development GO:0002064 34 0.035
Fly
regulation of adherens junction organization GO:1903391 21 0.035
response to biotic stimulus GO:0009607 276 0.035
extrinsic apoptotic signaling pathway GO:0097191 119 0.035
positive regulation of cell cycle process GO:0090068 106 0.034
cell part morphogenesis GO:0032990 137 0.034
regulation of endopeptidase activity GO:0052548 170 0.034
negative regulation of programmed cell death GO:0043069 321 0.034
mitotic cell cycle GO:0000278 326 0.034
pseudopodium assembly GO:0031269 7 0.034
regulation of cell shape GO:0008360 48 0.033
Fly
neurological system process GO:0050877 163 0.033
negative regulation of cytokine production GO:0001818 82 0.033
regulation of proteolysis GO:0030162 293 0.032
lamellipodium organization GO:0097581 30 0.032
establishment of protein localization to membrane GO:0090150 121 0.032
cellular response to metal ion GO:0071248 43 0.032
positive regulation of cell migration GO:0030335 172 0.032
regulation of cellular amine metabolic process GO:0033238 11 0.032
myeloid leukocyte migration GO:0097529 62 0.031
covalent chromatin modification GO:0016569 254 0.031
organelle localization GO:0051640 84 0.031
positive regulation of cell matrix adhesion GO:0001954 23 0.031
ribonucleoside catabolic process GO:0042454 406 0.030
leukocyte cell cell adhesion GO:0007159 37 0.030
spermatid development GO:0007286 4 0.029
regulation of cell size GO:0008361 19 0.029
internal protein amino acid acetylation GO:0006475 101 0.029
regulation of intracellular transport GO:0032386 195 0.029
negative regulation of transport GO:0051051 176 0.029
purine nucleoside monophosphate catabolic process GO:0009128 158 0.029
dendritic spine morphogenesis GO:0060997 3 0.029
hair follicle morphogenesis GO:0031069 2 0.029
neuron differentiation GO:0030182 138 0.029
regulation of chromosome segregation GO:0051983 44 0.028
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.028
response to external biotic stimulus GO:0043207 261 0.028
regulation of cysteine type endopeptidase activity GO:2000116 127 0.028
organelle fission GO:0048285 149 0.028
single organism behavior GO:0044708 28 0.028
regulation of cell migration GO:0030334 289 0.028
regulation of cell cell adhesion GO:0022407 57 0.028
regulation of protein localization to nucleus GO:1900180 85 0.028
regulation of apoptotic signaling pathway GO:2001233 175 0.027
regulation of nervous system development GO:0051960 88 0.027
vesicle mediated transport GO:0016192 371 0.027
cell activation GO:0001775 213 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
cell morphogenesis involved in differentiation GO:0000904 144 0.026
focal adhesion assembly GO:0048041 30 0.026
pseudopodium organization GO:0031268 8 0.026
nuclear import GO:0051170 106 0.026
maintenance of location GO:0051235 112 0.026
protein processing GO:0016485 226 0.025
regulation of cell development GO:0060284 161 0.025
histone modification GO:0016570 251 0.025
cell division GO:0051301 168 0.025
regulation of mitotic cell cycle GO:0007346 189 0.025
negative regulation of protein kinase activity GO:0006469 98 0.024
negative regulation of developmental process GO:0051093 247 0.024
regulation of cell adhesion mediated by integrin GO:0033628 22 0.024
regulation of respiratory burst GO:0060263 8 0.024
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.024
protein import into nucleus GO:0006606 104 0.024
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.023
negative regulation of protein modification process GO:0031400 200 0.023
cellular response to abiotic stimulus GO:0071214 117 0.023
vesicle localization GO:0051648 26 0.023
nucleocytoplasmic transport GO:0006913 176 0.023
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.023
regulation of establishment of protein localization GO:0070201 242 0.022
purine nucleotide biosynthetic process GO:0006164 84 0.022
asymmetric neuroblast division GO:0055059 1 0.022
negative regulation of actin nucleation GO:0051126 3 0.022
negative regulation of protein metabolic process GO:0051248 391 0.022
adult locomotory behavior GO:0008344 1 0.022
regulation of intracellular protein transport GO:0033157 123 0.021
cellular macromolecule catabolic process GO:0044265 380 0.021
regulation of attachment of spindle microtubules to kinetochore GO:0051988 9 0.021
response to wounding GO:0009611 168 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
regulation of protein localization to plasma membrane GO:1903076 40 0.021
epidermal growth factor receptor signaling pathway GO:0007173 39 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
negative regulation of organelle organization GO:0010639 126 0.021
regulation of behavior GO:0050795 82 0.021
positive regulation of transport GO:0051050 336 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.021
Human
negative regulation of cell differentiation GO:0045596 171 0.021
cytoplasmic transport GO:0016482 379 0.021
regulation of dna metabolic process GO:0051052 153 0.021
negative regulation of growth GO:0045926 97 0.021
cytokine production GO:0001816 247 0.021
atp metabolic process GO:0046034 176 0.021
negative regulation of cell cycle GO:0045786 193 0.020
regulation of cell morphogenesis GO:0022604 153 0.020
Fly
membrane budding GO:0006900 28 0.020
regulation of protein import into nucleus GO:0042306 78 0.020
neuroblast division GO:0055057 1 0.020
cellular response to biotic stimulus GO:0071216 71 0.020
chemotaxis GO:0006935 157 0.020
transmembrane transport GO:0055085 399 0.020
cdc42 protein signal transduction GO:0032488 4 0.019
protein acylation GO:0043543 138 0.019
receptor mediated endocytosis GO:0006898 84 0.019
negative regulation of cell size GO:0045792 3 0.019
ubiquitin dependent protein catabolic process GO:0006511 206 0.019
g protein coupled receptor signaling pathway GO:0007186 207 0.019
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.019
negative regulation of kinase activity GO:0033673 106 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.019
rhythmic behavior GO:0007622 2 0.019
response to transforming growth factor beta GO:0071559 94 0.019
neuron development GO:0048666 113 0.019
positive regulation of response to external stimulus GO:0032103 88 0.019
response to organic cyclic compound GO:0014070 204 0.019
response to inorganic substance GO:0010035 127 0.018
histone acetylation GO:0016573 93 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
lipid metabolic process GO:0006629 381 0.018
regulation of protein ubiquitination GO:0031396 95 0.018
circulatory system development GO:0072359 262 0.018
regulation of lamellipodium assembly GO:0010591 14 0.018
regulation of protein processing GO:0070613 150 0.018
regeneration GO:0031099 4 0.018
actin filament based movement GO:0030048 17 0.018
negative regulation of protein maturation GO:1903318 142 0.018
cyclic purine nucleotide metabolic process GO:0052652 60 0.018
cyclic nucleotide biosynthetic process GO:0009190 61 0.017
cellular response to inorganic substance GO:0071241 45 0.017
cellular protein catabolic process GO:0044257 261 0.017
regulation of neural precursor cell proliferation GO:2000177 4 0.017
regulation of binding GO:0051098 111 0.017
ossification GO:0001503 121 0.017
engulfment of apoptotic cell GO:0043652 2 0.017
positive regulation of stress fiber assembly GO:0051496 22 0.017
positive regulation of cell adhesion GO:0045785 84 0.017
positive regulation of protein transport GO:0051222 135 0.017
sensory perception of smell GO:0007608 2 0.017
regulation of peptidase activity GO:0052547 180 0.017
anterior posterior axis specification GO:0009948 2 0.017
reproductive process GO:0022414 106 0.017
Fly
morphogenesis of embryonic epithelium GO:0016331 4 0.017
Fly
regulation of cell motility GO:2000145 299 0.017
circadian behavior GO:0048512 2 0.017
cell substrate adhesion GO:0031589 132 0.017
cell growth GO:0016049 160 0.016
Fly
stem cell division GO:0017145 2 0.016
protein catabolic process GO:0030163 325 0.016
mitotic nuclear division GO:0007067 119 0.016
positive regulation of apoptotic signaling pathway GO:2001235 70 0.016
g1 s transition of mitotic cell cycle GO:0000082 78 0.016
atp catabolic process GO:0006200 157 0.016
protein maturation GO:0051604 233 0.016
single organism nuclear import GO:1902593 104 0.016
maintenance of protein location in cell GO:0032507 56 0.016
ribonucleoside monophosphate metabolic process GO:0009161 187 0.016
proteasomal protein catabolic process GO:0010498 176 0.016
regulation of proteasomal protein catabolic process GO:0061136 87 0.016
leukocyte activation GO:0045321 164 0.015
peptidyl lysine acetylation GO:0018394 101 0.015
immune response GO:0006955 307 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.015
syncytium formation by plasma membrane fusion GO:0000768 2 0.015
regulation of epidermal growth factor receptor signaling pathway GO:0042058 27 0.015
positive regulation of cell cycle GO:0045787 140 0.015
nucleoside phosphate biosynthetic process GO:1901293 109 0.015
stress fiber assembly GO:0043149 40 0.015
ribonucleotide biosynthetic process GO:0009260 81 0.015
immune effector process GO:0002252 159 0.015
plasma membrane organization GO:0007009 115 0.015
monosaccharide transport GO:0015749 32 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
organic hydroxy compound transport GO:0015850 63 0.015
cell cell junction organization GO:0045216 69 0.015
carbohydrate transport GO:0008643 37 0.015
internal peptidyl lysine acetylation GO:0018393 97 0.015
negative regulation of jun kinase activity GO:0043508 4 0.015
cell substrate adherens junction assembly GO:0007045 30 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.015
tube development GO:0035295 125 0.015
cell type specific apoptotic process GO:0097285 125 0.014
Rat
positive regulation of pseudopodium assembly GO:0031274 7 0.014
muscle cell differentiation GO:0042692 63 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
positive regulation of proteolysis GO:0045862 142 0.014
negative regulation of cytoplasmic transport GO:1903650 46 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
nuclear transport GO:0051169 179 0.014
maintenance of protein location GO:0045185 57 0.014
translational initiation GO:0006413 48 0.014
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
regulation of cellular protein catabolic process GO:1903362 96 0.014
autophagy GO:0006914 88 0.014
ribonucleoside monophosphate catabolic process GO:0009158 158 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
regulation of protein transport GO:0051223 213 0.014
protein import GO:0017038 130 0.014
regulation of chromosome organization GO:0033044 103 0.014
intracellular protein transport GO:0006886 270 0.014
nuclear division GO:0000280 128 0.014
circulatory system process GO:0003013 113 0.014
taxis GO:0042330 157 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
i kappab kinase nf kappab signaling GO:0007249 166 0.014
epithelial cell migration GO:0010631 119 0.014
hippocampus development GO:0021766 1 0.014
neuroblast proliferation GO:0007405 4 0.014
system process GO:0003008 349 0.014
lipid transport GO:0006869 90 0.014
positive regulation of lamellipodium organization GO:1902745 12 0.014
response to virus GO:0009615 126 0.014
regulation of defense response GO:0031347 154 0.014
cytokinesis GO:0000910 96 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.013
methylation GO:0032259 106 0.013
mitotic cell cycle process GO:1903047 286 0.013
muscle structure development GO:0061061 98 0.013
aging GO:0007568 66 0.013
regulation of chemotaxis GO:0050920 74 0.013

MAP3K11 disease predictions

Disease DO term ID Size Probability Func Analog Org
urinary system disease DOID:18 40 0.056
kidney disease DOID:557 36 0.033
central nervous system disease DOID:331 186 0.030
nervous system disease DOID:863 431 0.030
disease of metabolism DOID:0014667 295 0.026
inherited metabolic disorder DOID:655 242 0.016