|
|
cell development
|
GO:0048468 |
328 |
0.691
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.593
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.582
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.576
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.539
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.534
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.528
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.510
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.491
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.490
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.483
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.462
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.459
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.446
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.442
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.425
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.421
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.416
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.390
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.373
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.369
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.365
|
Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
0.353
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.349
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.331
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.328
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.320
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.316
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.298
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.296
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.263
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.252
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.251
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.250
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.246
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.242
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.241
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.241
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.238
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.233
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.229
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.228
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.220
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.219
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.214
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.214
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.207
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.204
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.198
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.190
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.188
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.187
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.187
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.186
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.176
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.174
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.170
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.170
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.166
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.164
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.161
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.154
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.150
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.148
|
Human Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.147
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.142
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.141
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.139
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.138
|
Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.137
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.137
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.137
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.137
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.135
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.132
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.130
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.130
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.127
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.112
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.110
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.107
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.103
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.103
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.102
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.100
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.100
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.100
|
Fly |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.099
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.099
|
Human Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.098
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.098
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.098
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.097
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.096
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.096
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.095
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.094
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.093
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.090
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.088
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.088
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.087
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.086
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.085
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.084
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.084
|
Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.082
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.079
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.079
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.078
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.078
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.078
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.078
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.077
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.077
|
Human |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.077
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.075
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.075
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.074
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.074
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.074
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.073
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.073
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.073
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.073
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.072
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.070
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.069
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.069
|
Fly |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.069
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.069
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.067
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.067
|
Fly |
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.067
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.066
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.066
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.066
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.065
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.064
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.064
|
|
|
|
system process
|
GO:0003008 |
349 |
0.064
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.064
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.064
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.063
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.063
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.063
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.062
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.061
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.061
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.061
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.060
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.059
|
Fly |
|
|
reproductive process
|
GO:0022414 |
106 |
0.059
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.059
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.058
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.058
|
Human Fly |
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.058
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.058
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.057
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.057
|
Human |
|
|
cell junction organization
|
GO:0034330 |
79 |
0.057
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.056
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.056
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.055
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.055
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.054
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.054
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.054
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.054
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.053
|
Human Fly |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.053
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.053
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.052
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.052
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.051
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.051
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.050
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.050
|
Human Fly |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.050
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.049
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.049
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.049
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.049
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.048
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.048
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.048
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.047
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.047
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.047
|
Human Fly |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.046
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.046
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.045
|
Fly |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.045
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.045
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.045
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.045
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.045
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.044
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.044
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.043
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.043
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.043
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.043
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.042
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.042
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.042
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.042
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.042
|
Human |
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.040
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.040
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.040
|
Human |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.040
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.039
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.039
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.039
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.039
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.039
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.039
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.039
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.039
|
Human Fly |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.039
|
Human Fly |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.038
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.038
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.038
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.037
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.037
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.037
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.037
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.036
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.036
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.036
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.036
|
|
|
|
growth
|
GO:0040007 |
202 |
0.036
|
Fly |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.036
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.035
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.035
|
Fly |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.035
|
Human Fly |
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.034
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.034
|
Human |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.034
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.034
|
Human |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.033
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.033
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.033
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.033
|
Human Fly |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.033
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.033
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
2 |
0.033
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.033
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.032
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.032
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.032
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.032
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.032
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.032
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.031
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.031
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.031
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.031
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.030
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.030
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.030
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.030
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.030
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.030
|
Human |
|
|
response to glucagon
|
GO:0033762 |
1 |
0.030
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.030
|
Fly |
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.030
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.030
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.029
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.029
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.029
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.029
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.029
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.029
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.029
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.028
|
Fly |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.028
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.028
|
Fly |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.028
|
Human Fly |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.028
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.027
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.027
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.027
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.027
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.027
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.027
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.026
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.026
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.025
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.025
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.025
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.025
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.025
|
Fly |
|
|
embryo development
|
GO:0009790 |
123 |
0.025
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.025
|
Human |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.025
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.025
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.025
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.025
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.025
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.024
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.024
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.024
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.024
|
|
|
|
establishment of endothelial barrier
|
GO:0061028 |
16 |
0.024
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.024
|
Human Fly |
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.024
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.024
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.024
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.024
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.024
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.024
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.023
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.023
|
Fly |
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.023
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.023
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.023
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.023
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.023
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.023
|
Human |
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.023
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.023
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.023
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.022
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.022
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.022
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.022
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.022
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.022
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.022
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.022
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.022
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.022
|
Human Fly |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.022
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.022
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.022
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.022
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.022
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.021
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.021
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.021
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.021
|
|
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.021
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.021
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.021
|
|
|
|
regulation of pro b cell differentiation
|
GO:2000973 |
1 |
0.021
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.021
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.021
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.021
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.021
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.021
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.021
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
27 |
0.021
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.021
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.020
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.020
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.020
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.020
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.020
|
Fly |
|
|
regulation of rap protein signal transduction
|
GO:0032487 |
9 |
0.020
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.020
|
Human |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.020
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.020
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.019
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.019
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.019
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.019
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.019
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.019
|
|
|
|
endothelial cell development
|
GO:0001885 |
18 |
0.019
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.019
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.019
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.019
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.019
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.019
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.019
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.019
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.019
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.019
|
|
|
|
hard palate development
|
GO:0060022 |
1 |
0.019
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.019
|
Fly |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.019
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.018
|
Human |
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.018
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.018
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.018
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.018
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.018
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.018
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.018
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.018
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.018
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.018
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.018
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.017
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.017
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.017
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.017
|
Fly |
|
|
cilium organization
|
GO:0044782 |
68 |
0.017
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.017
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.017
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.017
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.017
|
Fly |
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.017
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.017
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.017
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.017
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.017
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.016
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.016
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.016
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.016
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.016
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.016
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.016
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.016
|
|
|
|
cellular response to camp
|
GO:0071320 |
21 |
0.016
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.016
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.016
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.016
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.016
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.015
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.015
|
|
|
|
endothelium development
|
GO:0003158 |
33 |
0.015
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
48 |
0.015
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.015
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.015
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.015
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
3 |
0.015
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.015
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.015
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.015
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.015
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.015
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.015
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.015
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.015
|
Human |
|
|
head development
|
GO:0060322 |
108 |
0.015
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.015
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.015
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.014
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.014
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.014
|
Human |
|
|
endothelial cell differentiation
|
GO:0045446 |
26 |
0.014
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.014
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.014
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.014
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.014
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.014
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.014
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.014
|
Fly |
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.014
|
|
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
2 |
0.014
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.014
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.014
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.014
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.013
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.013
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.013
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.013
|
|
|
|
translation
|
GO:0006412 |
132 |
0.013
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.013
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.013
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.013
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.013
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.013
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.013
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.013
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.013
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.013
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.013
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.013
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.013
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.013
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.013
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.013
|
Fly |
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.013
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.013
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.013
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.013
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.012
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.012
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.012
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.012
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.012
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.012
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.012
|
|
