Homo sapiens

83 known processes

MAPK14

mitogen-activated protein kinase 14

(Aliases: EXIP,CSBP1,Mxi2,CSBP2,p38ALPHA,CSBP,p38,SAPK2A,RK,CSPB1,PRKM15,PRKM14)

MAPK14 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to nitrosative stress GO:0051409 4 1.000
jun phosphorylation GO:0007258 28 1.000
Human
inactivation of mapk activity GO:0000188 5 1.000
negative regulation of erk1 and erk2 cascade GO:0070373 14 1.000
negative regulation of protein serine threonine kinase activity GO:0071901 57 1.000
regulation of protein serine threonine kinase activity GO:0071900 179 1.000
peptidyl serine phosphorylation GO:0018105 101 1.000
Human Mouse Worm
peptidyl serine modification GO:0018209 106 1.000
Human Mouse Worm
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 1.000
chromatin modification GO:0016568 298 1.000
Human
erk1 and erk2 cascade GO:0070371 104 1.000
regulation of erk1 and erk2 cascade GO:0070372 99 1.000
positive regulation of protein phosphorylation GO:0001934 313 1.000
Fly
peptidyl tyrosine dephosphorylation GO:0035335 36 1.000
response to salt stress GO:0009651 3 1.000
Fly
small gtpase mediated signal transduction GO:0007264 78 1.000
regulation of map kinase activity GO:0043405 108 1.000
ras protein signal transduction GO:0007265 73 1.000
signal transduction by phosphorylation GO:0023014 297 0.999
regulation of mapk cascade GO:0043408 262 0.999
regulation of cytokine production GO:0001817 232 0.999
Human
positive regulation of apoptotic process GO:0043065 246 0.999
peptidyl threonine phosphorylation GO:0018107 41 0.999
Human
covalent chromatin modification GO:0016569 254 0.999
Human
regulation of kinase activity GO:0043549 314 0.998
regulation of translation GO:0006417 89 0.997
cytokine production GO:0001816 247 0.997
Human
rna stabilization GO:0043489 18 0.997
mapk cascade GO:0000165 288 0.996
negative regulation of map kinase activity GO:0043407 27 0.995
negative regulation of cellular protein metabolic process GO:0032269 353 0.995
cellular response to dna damage stimulus GO:0006974 379 0.994
stress activated protein kinase signaling cascade GO:0031098 94 0.994
Human Mouse Rat Worm
positive regulation of programmed cell death GO:0043068 249 0.993
negative regulation of protein phosphorylation GO:0001933 140 0.993
regulation of protein kinase activity GO:0045859 289 0.993
response to cytokine GO:0034097 232 0.993
defense response GO:0006952 315 0.993
Worm Fly
histone serine phosphorylation GO:0035404 4 0.993
innate immune response activating signal transduction GO:0002758 48 0.992
negative regulation of ras protein signal transduction GO:0046580 11 0.992
p38mapk cascade GO:0038066 9 0.992
Mouse Worm
protein dephosphorylation GO:0006470 81 0.991
negative regulation of catalytic activity GO:0043086 335 0.991
activation of mapk activity GO:0000187 45 0.991
negative regulation of apoptotic process GO:0043066 316 0.990
Human
negative regulation of protein metabolic process GO:0051248 391 0.989
response to osmotic stress GO:0006970 17 0.989
Human Yeast Worm Fly
cellular response to mechanical stimulus GO:0071260 39 0.988
Human
regulation of small gtpase mediated signal transduction GO:0051056 156 0.988
response to inorganic substance GO:0010035 127 0.987
Worm Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.985
negative regulation of small gtpase mediated signal transduction GO:0051058 12 0.985
protein autophosphorylation GO:0046777 123 0.984
Rat
response to lipopolysaccharide GO:0032496 70 0.984
positive regulation of defense response GO:0031349 87 0.984
response to lipid GO:0033993 206 0.982
mrna stabilization GO:0048255 18 0.982
tor signaling GO:0031929 39 0.980
negative regulation of phosphorylation GO:0042326 174 0.980
immune response regulating signaling pathway GO:0002764 97 0.977
regulation of cellular response to stress GO:0080135 244 0.977
Fly
posttranscriptional regulation of gene expression GO:0010608 213 0.975
positive regulation of cell death GO:0010942 263 0.973
protein deacylation GO:0035601 39 0.972
Human
positive regulation of immune response GO:0050778 159 0.972
internal protein amino acid acetylation GO:0006475 101 0.971
regulation of ras protein signal transduction GO:0046578 155 0.970
dna damage induced protein phosphorylation GO:0006975 5 0.968
regulation of stress activated mapk cascade GO:0032872 84 0.968
negative regulation of mapk cascade GO:0043409 56 0.966
regulation of jnk cascade GO:0046328 73 0.965
stress activated mapk cascade GO:0051403 93 0.964
Human Mouse Rat Worm
jnk cascade GO:0007254 80 0.963
Human
response to nitrogen compound GO:1901698 184 0.959
Mouse
histone h2a s1 phosphorylation GO:0043990 1 0.958
post embryonic development GO:0009791 2 0.957
Worm Fly
dephosphorylation GO:0016311 209 0.956
negative regulation of intracellular signal transduction GO:1902532 183 0.952
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.950
response to abiotic stimulus GO:0009628 336 0.950
cellular senescence GO:0090398 34 0.944
histone phosphorylation GO:0016572 16 0.944
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.943
cellular response to lipid GO:0071396 127 0.942
activation of immune response GO:0002253 114 0.941
interleukin 1 mediated signaling pathway GO:0070498 12 0.939
transposition rna mediated GO:0032197 0 0.938
multicellular organismal aging GO:0010259 3 0.936
Fly
innate immune response GO:0045087 178 0.932
Worm Fly
activation of protein kinase activity GO:0032147 90 0.931
response to reactive oxygen species GO:0000302 61 0.927
Worm Fly
regulation of transferase activity GO:0051338 355 0.925
regulation of histone phosphorylation GO:0033127 5 0.923
signal transduction in response to dna damage GO:0042770 57 0.923
regulation of cell cycle GO:0051726 393 0.919
Yeast
chromatin organization GO:0006325 351 0.918
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.916
response to interleukin 1 GO:0070555 47 0.914
embryo development GO:0009790 123 0.914
Worm
positive regulation of mapk cascade GO:0043410 190 0.913
peptidyl lysine modification GO:0018205 144 0.909
immune response GO:0006955 307 0.905
Worm Fly
translation GO:0006412 132 0.904
mucosal immune response GO:0002385 21 0.900
Fly
defense response to other organism GO:0098542 129 0.899
Worm Fly
cellular response to reactive oxygen species GO:0034614 50 0.886
Fly
response to metal ion GO:0010038 84 0.884
Fly
cellular response to abiotic stimulus GO:0071214 117 0.883
histone acetylation GO:0016573 93 0.883
muscle system process GO:0003012 81 0.880
defense response to gram negative bacterium GO:0050829 14 0.877
Worm
regulation of cellular ketone metabolic process GO:0010565 50 0.876
nervous system development GO:0007399 293 0.875
response to bacterium GO:0009617 144 0.875
anatomical structure formation involved in morphogenesis GO:0048646 284 0.874
Yeast Mouse
cell junction maintenance GO:0034331 4 0.871
heart development GO:0007507 95 0.867
Fly
regulation of chromatin organization GO:1902275 56 0.851
Human
positive regulation of protein kinase activity GO:0045860 190 0.848
regulation of mrna stability GO:0043488 23 0.848
negative regulation of protein kinase activity GO:0006469 98 0.848
female gamete generation GO:0007292 2 0.846
negative regulation of transferase activity GO:0051348 124 0.846
arachidonic acid metabolic process GO:0019369 14 0.843
peptidyl lysine acetylation GO:0018394 101 0.840
regulation of rna stability GO:0043487 23 0.839
regulation of innate immune response GO:0045088 97 0.833
Fly
positive regulation of hydrolase activity GO:0051345 331 0.833
Human
activation of innate immune response GO:0002218 55 0.827
positive regulation of phosphorylation GO:0042327 394 0.825
Fly
cellular response to endogenous stimulus GO:0071495 336 0.821
Fly
cellular amine metabolic process GO:0044106 41 0.820
peptidyl threonine modification GO:0018210 45 0.815
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.807
mapk import into nucleus GO:0000189 1 0.798
cellular component morphogenesis GO:0032989 314 0.796
Yeast Mouse
apoptotic signaling pathway GO:0097190 268 0.796
organ morphogenesis GO:0009887 147 0.790
Mouse Fly
cellular response to lipopolysaccharide GO:0071222 57 0.789
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.789
protein deacetylation GO:0006476 38 0.780
Human
cellular response to oxygen containing compound GO:1901701 276 0.780
response to heat GO:0009408 21 0.778
Yeast Fly
regulation of gene expression epigenetic GO:0040029 73 0.776
establishment of protein localization to organelle GO:0072594 172 0.775
Mouse
translational initiation GO:0006413 48 0.772
regulation of peptidase activity GO:0052547 180 0.768
response to oxygen containing compound GO:1901700 369 0.768
response to molecule of bacterial origin GO:0002237 82 0.764
immune response activating signal transduction GO:0002757 90 0.762
response to oxidative stress GO:0006979 121 0.761
Worm Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.760
circulatory system process GO:0003013 113 0.757
oocyte differentiation GO:0009994 2 0.755
tube development GO:0035295 125 0.743
defense response to bacterium GO:0042742 63 0.741
Worm Fly
negative regulation of peptidase activity GO:0010466 91 0.741
response to mechanical stimulus GO:0009612 51 0.729
Human
regulation of multi organism process GO:0043900 157 0.715
Fly
cellular response to molecule of bacterial origin GO:0071219 62 0.713
circulatory system development GO:0072359 262 0.707
Mouse Fly
gtp metabolic process GO:0046039 239 0.703
cellular amino acid metabolic process GO:0006520 116 0.701
regulation of immune response GO:0050776 201 0.700
Fly
response to growth factor GO:0070848 205 0.697
positive regulation of histone phosphorylation GO:0033129 3 0.695
positive regulation of map kinase activity GO:0043406 80 0.693
regulation of hepatic stellate cell activation GO:2000489 1 0.686
positive regulation of multi organism process GO:0043902 56 0.679
regulation of chromosome organization GO:0033044 103 0.677
Human
negative regulation of jnk cascade GO:0046329 16 0.675
positive regulation of cytokine production GO:0001819 167 0.673
Human
positive regulation of cell size GO:0045793 3 0.673
Fly
regulation of tumor necrosis factor production GO:0032680 43 0.667
nuclear transport GO:0051169 179 0.666
Mouse
chordate embryonic development GO:0043009 34 0.664
3 utr mediated mrna stabilization GO:0070935 8 0.663
cell adhesion GO:0007155 325 0.662
cellular response to nitrogen compound GO:1901699 144 0.661
regulation of cellular amino acid metabolic process GO:0006521 6 0.657
system process GO:0003008 349 0.655
negative regulation of binding GO:0051100 57 0.652
Human
developmental process involved in reproduction GO:0003006 66 0.648
Yeast Worm
cellular response to growth factor stimulus GO:0071363 197 0.644
regulation of mitotic cell cycle GO:0007346 189 0.640
response to radiation GO:0009314 151 0.639
negative regulation of protein modification process GO:0031400 200 0.635
cellular response to cytokine stimulus GO:0071345 181 0.634
pattern recognition receptor signaling pathway GO:0002221 48 0.633
negative regulation of programmed cell death GO:0043069 321 0.632
Human
negative regulation of kinase activity GO:0033673 106 0.623
positive regulation of organic acid transport GO:0032892 3 0.622
histone modification GO:0016570 251 0.621
Human
response to biotic stimulus GO:0009607 276 0.620
oogenesis GO:0048477 2 0.614
cellular response to interleukin 1 GO:0071347 35 0.600
embryo development ending in birth or egg hatching GO:0009792 34 0.599
Worm
vascular endothelial growth factor receptor signaling pathway GO:0048010 19 0.592
negative regulation of mitotic cell cycle GO:0045930 102 0.591
regulation of anatomical structure size GO:0090066 101 0.584
Fly
dna damage checkpoint GO:0000077 68 0.584
Mouse
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 3 0.582
regulation of protein acetylation GO:1901983 25 0.575
regulation of rho protein signal transduction GO:0035023 79 0.570
hyperosmotic response GO:0006972 4 0.568
Yeast Worm
regulation of endopeptidase activity GO:0052548 170 0.565
protein processing GO:0016485 226 0.556
regulation of locomotion GO:0040012 329 0.551
dna damage response signal transduction resulting in transcription GO:0042772 12 0.550
oocyte development GO:0048599 1 0.546
positive regulation of innate immune response GO:0045089 79 0.541
embryonic placenta development GO:0001892 1 0.531
purine ribonucleotide catabolic process GO:0009154 404 0.530
dna replication GO:0006260 116 0.528
Yeast
regulation of defense response GO:0031347 154 0.524
Fly
regulation of cysteine type endopeptidase activity GO:2000116 127 0.523
dna integrity checkpoint GO:0031570 71 0.511
Mouse
regulation of histone acetylation GO:0035065 19 0.511
positive regulation of cellular component organization GO:0051130 376 0.510
Mouse
interleukin 6 production GO:0032635 37 0.509
Human
posttranscriptional gene silencing by rna GO:0035194 25 0.502
positive regulation of catabolic process GO:0009896 310 0.499
regulation of cell differentiation GO:0045595 393 0.499
Human Yeast Mouse
response to axon injury GO:0048678 1 0.498
regulation of histone modification GO:0031056 47 0.493
Human
tumor necrosis factor production GO:0032640 43 0.489
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.471
regulation of peptidyl lysine acetylation GO:2000756 22 0.464
positive regulation of icosanoid secretion GO:0032305 3 0.458
negative regulation of stress activated protein kinase signaling cascade GO:0070303 19 0.452
reproductive process GO:0022414 106 0.451
Yeast Worm
internal peptidyl lysine acetylation GO:0018393 97 0.442
cytokine mediated signaling pathway GO:0019221 109 0.441
cellular response to arsenic containing substance GO:0071243 4 0.441
Fly
protein localization to organelle GO:0033365 280 0.438
Mouse Worm
regulation of cellular component size GO:0032535 82 0.437
Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.436
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.435
dna dependent dna replication GO:0006261 44 0.431
Yeast
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.428
positive regulation of fatty acid transport GO:2000193 3 0.428
cellular response to metal ion GO:0071248 43 0.420
Fly
positive regulation of immune system process GO:0002684 283 0.420
Mouse
cell activation GO:0001775 213 0.412
regulation of behavior GO:0050795 82 0.405
negative regulation of cell cycle GO:0045786 193 0.397
cellular response to cadmium ion GO:0071276 8 0.397
Fly
positive regulation of transferase activity GO:0051347 227 0.396
cell morphogenesis GO:0000902 296 0.393
Mouse
negative regulation of protein processing GO:0010955 142 0.392
cellular response to external stimulus GO:0071496 111 0.387
Human
negative regulation of stress activated mapk cascade GO:0032873 19 0.384
purine ribonucleoside catabolic process GO:0046130 398 0.382
protein maturation GO:0051604 233 0.373
cellular response to heat GO:0034605 14 0.372
Yeast
negative regulation of endopeptidase activity GO:0010951 84 0.369
reproduction GO:0000003 63 0.368
Yeast Worm
nuclear import GO:0051170 106 0.365
Mouse
positive regulation of organelle organization GO:0010638 195 0.364
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.364
Mouse
response to hydrogen peroxide GO:0042542 40 0.361
Fly
regulation of protein targeting GO:1903533 91 0.360
Mouse
cellular response to vascular endothelial growth factor stimulus GO:0035924 26 0.356
single organismal cell cell adhesion GO:0016337 148 0.356
histone h2a phosphorylation GO:1990164 3 0.349
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.348
response to other organism GO:0051707 261 0.344
positive regulation of chromatin modification GO:1903310 30 0.344
regulation of translational initiation GO:0006446 24 0.343
protein acetylation GO:0006473 116 0.342
growth GO:0040007 202 0.341
Mouse Fly
cell development GO:0048468 328 0.339
Yeast Mouse
protein acylation GO:0043543 138 0.337
response to uv GO:0009411 73 0.333
Human
response to organic cyclic compound GO:0014070 204 0.330
blood vessel development GO:0001568 172 0.329
Mouse
regulation of cytoplasmic transport GO:1903649 149 0.328
Mouse
cell cycle checkpoint GO:0000075 117 0.324
Mouse
antimicrobial humoral response GO:0019730 26 0.321
Fly
histone deacetylation GO:0016575 32 0.317
Human
signal transduction by p53 class mediator GO:0072331 72 0.315
blood circulation GO:0008015 113 0.314
response to estrogen GO:0043627 47 0.312
generation of neurons GO:0048699 152 0.311
hematopoietic or lymphoid organ development GO:0048534 186 0.306
Mouse
determination of adult lifespan GO:0008340 2 0.302
Fly
regulation of cellular amine metabolic process GO:0033238 11 0.299
negative regulation of insulin receptor signaling pathway GO:0046627 8 0.296
stress induced premature senescence GO:0090400 5 0.295
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 17 0.294
Yeast
nucleoside triphosphate metabolic process GO:0009141 422 0.292
response to external biotic stimulus GO:0043207 261 0.291
ribonucleoside triphosphate metabolic process GO:0009199 412 0.290
defense response to fungus GO:0050832 4 0.285
Fly
positive regulation of intracellular protein transport GO:0090316 76 0.284
Mouse
negative regulation of proteolysis GO:0045861 132 0.280
cellular response to hormone stimulus GO:0032870 125 0.275
positive regulation of cell activation GO:0050867 81 0.272
cellular ketone metabolic process GO:0042180 80 0.268
tube morphogenesis GO:0035239 95 0.263
rho protein signal transduction GO:0007266 26 0.262
response to hormone GO:0009725 175 0.261
response to superoxide GO:0000303 6 0.257
Worm
oxidation reduction process GO:0055114 396 0.255
Mouse
cell aging GO:0007569 52 0.253
actin filament organization GO:0007015 128 0.252
positive regulation of cell differentiation GO:0045597 211 0.252
Human Mouse
regulation of protein localization GO:0032880 296 0.248
Human Mouse Worm
fatty acid metabolic process GO:0006631 115 0.248
Mouse
response to drug GO:0042493 81 0.245
negative regulation of cell death GO:0060548 345 0.242
Human
positive regulation of ion transport GO:0043270 87 0.241
protein targeting to nucleus GO:0044744 104 0.240
Mouse
cell cell signaling GO:0007267 155 0.236
Fly
foam cell differentiation GO:0090077 15 0.236
Human
purine nucleotide catabolic process GO:0006195 405 0.235
regulation of proteolysis GO:0030162 293 0.233
regulation of intracellular transport GO:0032386 195 0.233
Mouse
negative regulation of transposition GO:0010529 7 0.233
regulation of cell cycle process GO:0010564 266 0.231
Yeast
neurological system process GO:0050877 163 0.230
behavioral response to ethanol GO:0048149 2 0.226
macromolecule deacylation GO:0098732 41 0.226
Human
regulation of cellular component biogenesis GO:0044087 281 0.223
autophagy GO:0006914 88 0.220
extrinsic apoptotic signaling pathway GO:0097191 119 0.219
negative regulation of developmental process GO:0051093 247 0.218
Yeast
head development GO:0060322 108 0.217
negative regulation of immune system process GO:0002683 136 0.216
Fly
nuclear division GO:0000280 128 0.213
tissue morphogenesis GO:0048729 96 0.212
regulation of protein processing GO:0070613 150 0.209
peptidyl tyrosine phosphorylation GO:0018108 170 0.209
long chain fatty acid metabolic process GO:0001676 30 0.206
muscle contraction GO:0006936 73 0.206
reactive oxygen species metabolic process GO:0072593 75 0.205
cardiovascular system development GO:0072358 262 0.202
Mouse Fly
regulation of cell development GO:0060284 161 0.201
Mouse
negative regulation of organelle organization GO:0010639 126 0.199
regulation of chromatin modification GO:1903308 51 0.198
Human
negative regulation of humoral immune response GO:0002921 7 0.198
Fly
signal transduction in absence of ligand GO:0038034 22 0.197
protein localization to nucleus GO:0034504 136 0.197
Mouse Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.196
regulation of meiotic cell cycle GO:0051445 4 0.195
digestive tract morphogenesis GO:0048546 56 0.195
apoptotic mitochondrial changes GO:0008637 57 0.194
positive regulation of cell cycle GO:0045787 140 0.194
epithelium development GO:0060429 227 0.190
hepatic stellate cell activation GO:0035733 1 0.189
mrna destabilization GO:0061157 1 0.189
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.189
regulation of cell morphogenesis GO:0022604 153 0.183
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.183
g2 dna damage checkpoint GO:0031572 26 0.181
placenta development GO:0001890 10 0.181
locomotory behavior GO:0007626 1 0.179
regulation of intracellular protein transport GO:0033157 123 0.176
Mouse
monocarboxylic acid metabolic process GO:0032787 185 0.176
Mouse
photoreceptor cell differentiation GO:0046530 2 0.174
response to steroid hormone GO:0048545 80 0.174
positive regulation of kinase activity GO:0033674 204 0.174
bmp signaling pathway GO:0030509 49 0.173
Fly
cellular lipid metabolic process GO:0044255 303 0.172
Mouse
histone h3 s10 phosphorylation GO:0043987 3 0.170
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.170
Fly
regulation of nitric oxide synthase biosynthetic process GO:0051769 6 0.167
response to tumor necrosis factor GO:0034612 76 0.165
regulation of protein complex assembly GO:0043254 147 0.165
regulation of purine nucleotide metabolic process GO:1900542 264 0.163
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.160
chemotaxis GO:0006935 157 0.159
positive regulation of histone acetylation GO:0035066 11 0.159
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 9 0.158
Yeast
gene silencing GO:0016458 49 0.157
regulation of cellular component movement GO:0051270 334 0.155
negative regulation of chromatin silencing GO:0031936 4 0.153
regulation of prostaglandin secretion GO:0032306 2 0.152
glycosyl compound catabolic process GO:1901658 413 0.152
response to testosterone GO:0033574 1 0.151
t cell activation GO:0042110 99 0.151
cellular response to inorganic substance GO:0071241 45 0.150
Fly
response to temperature stimulus GO:0009266 22 0.150
Yeast Fly
acid secretion GO:0046717 12 0.149
histone h3 s28 phosphorylation GO:0043988 2 0.149
regulation of autophagy GO:0010506 52 0.146
cellular response to organonitrogen compound GO:0071417 124 0.146
neuron projection development GO:0031175 106 0.144
response to alcohol GO:0097305 64 0.143
rna interference GO:0016246 4 0.143
cellular macromolecular complex assembly GO:0034622 324 0.143
oocyte maturation GO:0001556 1 0.142
cellular response to biotic stimulus GO:0071216 71 0.141
central nervous system neuron axonogenesis GO:0021955 3 0.141
central nervous system development GO:0007417 123 0.141
ribonucleoside catabolic process GO:0042454 406 0.140
cell cycle arrest GO:0007050 71 0.139
positive regulation of prostaglandin secretion GO:0032308 1 0.139
positive regulation of ras gtpase activity GO:0032320 117 0.138
cellular response to calcium ion GO:0071277 19 0.137
mitotic cell cycle GO:0000278 326 0.136
mrna processing GO:0006397 133 0.134
digestive system development GO:0055123 75 0.134
tripartite regional subdivision GO:0007351 2 0.132
organelle fission GO:0048285 149 0.132
cell cell junction organization GO:0045216 69 0.130
anterior posterior axis specification embryo GO:0008595 2 0.129
negative regulation of locomotion GO:0040013 118 0.128
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 11 0.128
morphogenesis of an epithelium GO:0002009 60 0.126
behavior GO:0007610 112 0.124
regulation of protein polymerization GO:0032271 63 0.124
vesicle mediated transport GO:0016192 371 0.124
regulation of cell activation GO:0050865 125 0.122
negative regulation of protein maturation GO:1903318 142 0.121
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.121
cytoplasmic transport GO:0016482 379 0.121
Mouse
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.119
mrna metabolic process GO:0016071 175 0.119
positive regulation of cell development GO:0010720 92 0.118
golgi organization GO:0007030 38 0.118
negative regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress GO:1990441 1 0.115
response to organonitrogen compound GO:0010243 156 0.114
Mouse
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.113
regulation of protein binding GO:0043393 66 0.113
Human
regulation of reproductive process GO:2000241 15 0.113
response to transition metal nanoparticle GO:1990267 29 0.113
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.113
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 2 0.112
regulation of nucleocytoplasmic transport GO:0046822 98 0.112
Mouse
t cell differentiation in thymus GO:0033077 4 0.111
response to starvation GO:0042594 59 0.111
Fly
intracellular protein transport GO:0006886 270 0.110
Mouse
negative regulation of cell migration GO:0030336 102 0.109
regulation of protein maturation GO:1903317 150 0.108
cell cycle g1 s phase transition GO:0044843 80 0.106
positive regulation of deacetylase activity GO:0090045 6 0.106
Human
ribonucleotide catabolic process GO:0009261 405 0.106
regulation of establishment of protein localization GO:0070201 242 0.106
Mouse
establishment of vesicle localization GO:0051650 23 0.106
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.105
viral process GO:0016032 146 0.105
response to organophosphorus GO:0046683 41 0.104
regulation of cell motility GO:2000145 299 0.103
positive regulation of cellular catabolic process GO:0031331 284 0.103
ion homeostasis GO:0050801 230 0.103
regulation of cytoskeleton organization GO:0051493 177 0.102
regulation of gtp catabolic process GO:0033124 180 0.101
positive regulation of translational initiation GO:0045948 7 0.101
multi organism reproductive process GO:0044703 54 0.101
Yeast
amine metabolic process GO:0009308 44 0.101
mitochondrion organization GO:0007005 156 0.100
positive regulation of mitotic cell cycle GO:0045931 60 0.100
protein import GO:0017038 130 0.100
Mouse
cellular response to organic cyclic compound GO:0071407 127 0.099
regeneration GO:0031099 4 0.099
Mouse
purine ribonucleoside metabolic process GO:0046128 437 0.098
regulation of rho gtpase activity GO:0032319 66 0.098
collateral sprouting GO:0048668 2 0.098
synaptic transmission GO:0007268 61 0.097
Fly
regulation of ras gtpase activity GO:0032318 128 0.096
regulation of protein transport GO:0051223 213 0.096
Mouse
actin filament based process GO:0030029 224 0.095
biological adhesion GO:0022610 331 0.094
release of cytochrome c from mitochondria GO:0001836 35 0.094
positive regulation of apoptotic signaling pathway GO:2001235 70 0.094
intra s dna damage checkpoint GO:0031573 4 0.093
positive regulation of neurogenesis GO:0050769 49 0.093
positive regulation of wound healing GO:0090303 20 0.093
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.093
single organism cellular localization GO:1902580 332 0.091
Mouse
cellular response to osmotic stress GO:0071470 8 0.091
Yeast
interspecies interaction between organisms GO:0044419 156 0.091
embryonic morphogenesis GO:0048598 85 0.091
defense response to gram positive bacterium GO:0050830 29 0.090
Worm
cellular response to oxidative stress GO:0034599 85 0.089
Fly
neuron projection regeneration GO:0031102 1 0.087
mitotic cell cycle phase transition GO:0044772 162 0.086
regulation of protein deacetylation GO:0090311 12 0.085
Human
protein catabolic process GO:0030163 325 0.084
neurogenesis GO:0022008 169 0.083
organelle inheritance GO:0048308 2 0.083
single organism cell adhesion GO:0098602 179 0.082
response to purine containing compound GO:0014074 40 0.081
immune system development GO:0002520 195 0.081
Mouse
negative regulation of hydrolase activity GO:0051346 182 0.081
mapk export from nucleus GO:0045204 1 0.080
regulation of actin filament based process GO:0032970 141 0.080
regulation of binding GO:0051098 111 0.080
Human
regulation of transposition GO:0010528 7 0.080
positive regulation of translation GO:0045727 35 0.079
paracrine signaling GO:0038001 1 0.079
Fly
insulin receptor signaling pathway GO:0008286 23 0.078
epithelium migration GO:0090132 119 0.078
nucleoside phosphate catabolic process GO:1901292 412 0.078
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.078
toll like receptor signaling pathway GO:0002224 25 0.077
regulation of wound healing GO:0061041 56 0.077
response to oxygen radical GO:0000305 6 0.076
Worm

MAPK14 disease predictions

Disease DO term ID Size Probability Func Analog Org