Homo sapiens

141 known processes

MAPT

microtubule-associated protein tau

(Aliases: TAU,MGC138549,DDPAC,FLJ31424,FTDP-17,MTBT2,MSTD,MTBT1,PPND,MAPTL)

MAPT biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
serotonin uptake GO:0051610 2 0.999
positive regulation of synaptic transmission GO:0050806 4 0.998
peptidyl serine phosphorylation GO:0018105 101 0.998
microtubule cytoskeleton organization GO:0000226 176 0.997
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.997
organonitrogen compound biosynthetic process GO:1901566 200 0.994
neurotransmitter secretion GO:0007269 4 0.993
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.992
cell development GO:0048468 328 0.991
g protein coupled receptor signaling pathway GO:0007186 207 0.989
sodium ion transport GO:0006814 61 0.987
cell fate determination GO:0001709 3 0.986
sodium ion transmembrane transport GO:0035725 59 0.983
neuroblast division GO:0055057 1 0.983
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.983
regulation of neurotransmitter secretion GO:0046928 3 0.982
neuroblast proliferation GO:0007405 4 0.981
neuron differentiation GO:0030182 138 0.980
cellular amine metabolic process GO:0044106 41 0.979
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.979
anion transport GO:0006820 161 0.979
asymmetric neuroblast division GO:0055059 1 0.978
generation of neurons GO:0048699 152 0.977
positive regulation of cellular amine metabolic process GO:0033240 7 0.976
somatic stem cell division GO:0048103 1 0.973
amine metabolic process GO:0009308 44 0.973
regulation of neuron differentiation GO:0045664 70 0.972
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.971
peptidyl serine modification GO:0018209 106 0.969
regulation of peroxidase activity GO:2000468 2 0.969
asymmetric stem cell division GO:0098722 1 0.969
ion transmembrane transport GO:0034220 338 0.968
cellular ketone metabolic process GO:0042180 80 0.965
organic anion transport GO:0015711 103 0.964
positive regulation of anoikis GO:2000210 4 0.963
carboxylic acid transport GO:0046942 63 0.961
positive regulation of transport GO:0051050 336 0.958
regulation of microtubule polymerization GO:0031113 12 0.957
positive regulation of cellular component organization GO:0051130 376 0.955
organic acid transport GO:0015849 65 0.953
microtubule polymerization GO:0046785 18 0.948
cation transport GO:0006812 331 0.944
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.941
cellular carbohydrate metabolic process GO:0044262 84 0.933
neuronal stem cell division GO:0036445 1 0.932
protein autophosphorylation GO:0046777 123 0.928
regulation of membrane potential GO:0042391 95 0.916
positive regulation of developmental process GO:0051094 314 0.908
regulation of cellular amine metabolic process GO:0033238 11 0.898
negative regulation of ion transport GO:0043271 39 0.896
axonogenesis GO:0007409 31 0.887
regulation of cellular ketone metabolic process GO:0010565 50 0.883
single organism cellular localization GO:1902580 332 0.882
Mouse
amino acid transport GO:0006865 28 0.879
synaptic vesicle recycling GO:0036465 3 0.878
system process GO:0003008 349 0.875
cell projection organization GO:0030030 252 0.874
regulation of protein serine threonine kinase activity GO:0071900 179 0.873
negative regulation of endopeptidase activity GO:0010951 84 0.870
negative regulation of programmed cell death GO:0043069 321 0.870
regulation of oxidoreductase activity GO:0051341 43 0.865
stem cell division GO:0017145 2 0.864
regulation of ion transport GO:0043269 189 0.863
positive regulation of programmed cell death GO:0043068 249 0.860
female gamete generation GO:0007292 2 0.857
cellular component morphogenesis GO:0032989 314 0.853
neurogenesis GO:0022008 169 0.853
regulation of transferase activity GO:0051338 355 0.852
organophosphate biosynthetic process GO:0090407 163 0.849
ribonucleotide biosynthetic process GO:0009260 81 0.849
regulation of anatomical structure morphogenesis GO:0022603 286 0.847
regulation of axonogenesis GO:0050770 16 0.845
long term synaptic potentiation GO:0060291 1 0.844
response to oxygen containing compound GO:1901700 369 0.843
regulation of locomotion GO:0040012 329 0.842
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.834
negative regulation of apoptotic process GO:0043066 316 0.834
monovalent inorganic cation transport GO:0015672 128 0.832
regulation of neuron projection development GO:0010975 57 0.831
regulation of cell projection organization GO:0031344 107 0.829
microtubule based process GO:0007017 210 0.820
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.820
long term memory GO:0007616 2 0.813
regulation of neurogenesis GO:0050767 82 0.805
regulation of microtubule based process GO:0032886 74 0.802
regulation of synaptic plasticity GO:0048167 3 0.800
regulation of carbohydrate metabolic process GO:0006109 54 0.799
microtubule polymerization or depolymerization GO:0031109 37 0.799
response to organonitrogen compound GO:0010243 156 0.797
regulation of transporter activity GO:0032409 82 0.793
positive regulation of ion transport GO:0043270 87 0.791
positive regulation of cell proliferation GO:0008284 301 0.790
neuron development GO:0048666 113 0.783
establishment or maintenance of cell polarity GO:0007163 31 0.783
response to nitrogen compound GO:1901698 184 0.780
single organism carbohydrate metabolic process GO:0044723 193 0.775
regulation of nervous system development GO:0051960 88 0.772
enzyme linked receptor protein signaling pathway GO:0007167 303 0.766
transmembrane transport GO:0055085 399 0.765
nucleoside phosphate biosynthetic process GO:1901293 109 0.763
positive regulation of catabolic process GO:0009896 310 0.759
cell morphogenesis GO:0000902 296 0.758
nervous system development GO:0007399 293 0.756
positive regulation of neuron differentiation GO:0045666 40 0.755
locomotory behavior GO:0007626 1 0.742
Mouse
positive regulation of phosphorylation GO:0042327 394 0.728
lipid metabolic process GO:0006629 381 0.725
purine nucleotide biosynthetic process GO:0006164 84 0.717
metal ion transport GO:0030001 272 0.714
cell morphogenesis involved in differentiation GO:0000904 144 0.706
cellular response to endogenous stimulus GO:0071495 336 0.706
inorganic ion transmembrane transport GO:0098660 231 0.704
regulation of calcium ion transport GO:0051924 79 0.704
positive regulation of carbohydrate metabolic process GO:0045913 21 0.703
neuron projection development GO:0031175 106 0.702
regulation of inositol phosphate biosynthetic process GO:0010919 3 0.696
regulation of cell morphogenesis GO:0022604 153 0.695
dopamine uptake involved in synaptic transmission GO:0051583 4 0.686
positive regulation of cell death GO:0010942 263 0.682
positive regulation of neuron projection development GO:0010976 34 0.674
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.672
amino acid import GO:0043090 4 0.671
positive regulation of cytoplasmic transport GO:1903651 82 0.671
adult locomotory behavior GO:0008344 1 0.666
Mouse
nitrogen compound transport GO:0071705 191 0.660
neuron projection morphogenesis GO:0048812 50 0.658
organic hydroxy compound metabolic process GO:1901615 147 0.654
cellular amino acid metabolic process GO:0006520 116 0.653
anion transmembrane transport GO:0098656 76 0.653
regulation of phospholipase activity GO:0010517 26 0.653
carbohydrate metabolic process GO:0005975 207 0.652
positive regulation of protein phosphorylation GO:0001934 313 0.650
l amino acid import GO:0043092 4 0.641
covalent chromatin modification GO:0016569 254 0.640
regulation of cellular amino acid metabolic process GO:0006521 6 0.638
negative regulation of protein processing GO:0010955 142 0.637
carbohydrate transport GO:0008643 37 0.629
cyclic purine nucleotide metabolic process GO:0052652 60 0.624
purine ribonucleotide biosynthetic process GO:0009152 79 0.624
regulation of microtubule cytoskeleton organization GO:0070507 61 0.623
oogenesis GO:0048477 2 0.621
cellular ion homeostasis GO:0006873 168 0.621
axon development GO:0061564 34 0.620
cyclic nucleotide biosynthetic process GO:0009190 61 0.620
cyclic nucleotide metabolic process GO:0009187 82 0.613
positive regulation of oxidoreductase activity GO:0051353 26 0.609
negative regulation of peptidase activity GO:0010466 91 0.608
regulation of establishment of protein localization GO:0070201 242 0.602
alcohol metabolic process GO:0006066 114 0.599
d aspartate transport GO:0070777 3 0.593
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.585
response to drug GO:0042493 81 0.583
metal ion homeostasis GO:0055065 169 0.582
regulation of kinase activity GO:0043549 314 0.580
regulation of glucose import GO:0046324 21 0.578
organophosphate ester transport GO:0015748 32 0.576
secretion by cell GO:0032940 226 0.567
response to lipid GO:0033993 206 0.567
positive regulation of cell development GO:0010720 92 0.566
behavior GO:0007610 112 0.565
Mouse
regulation of synaptic vesicle exocytosis GO:2000300 2 0.560
multicellular organismal aging GO:0010259 3 0.557
carbohydrate derivative biosynthetic process GO:1901137 207 0.551
membrane organization GO:0061024 292 0.539
chemical homeostasis GO:0048878 306 0.538
cell part morphogenesis GO:0032990 137 0.534
cellular response to oxygen containing compound GO:1901701 276 0.533
cellular calcium ion homeostasis GO:0006874 117 0.532
regulation of ion transmembrane transport GO:0034765 132 0.521
positive regulation of apoptotic process GO:0043065 246 0.518
d aspartate import GO:0070779 3 0.517
growth GO:0040007 202 0.515
chemotaxis GO:0006935 157 0.515
regulation of proteolysis GO:0030162 293 0.514
response to hormone GO:0009725 175 0.514
positive regulation of cellular catabolic process GO:0031331 284 0.509
secretion GO:0046903 254 0.507
inorganic cation transmembrane transport GO:0098662 194 0.505
regulation of lipid metabolic process GO:0019216 96 0.505
reproductive process GO:0022414 106 0.504
Rat
regulation of homeostatic process GO:0032844 121 0.501
regulation of anion transport GO:0044070 25 0.501
anoikis GO:0043276 22 0.500
cellular response to nitrogen compound GO:1901699 144 0.500
regulation of cell differentiation GO:0045595 393 0.498
response to extracellular stimulus GO:0009991 85 0.496
Rat
cell type specific apoptotic process GO:0097285 125 0.484
regulation of protein localization GO:0032880 296 0.484
negative regulation of protein metabolic process GO:0051248 391 0.474
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.472
establishment of vesicle localization GO:0051650 23 0.470
regulation of endopeptidase activity GO:0052548 170 0.470
regulation of protein maturation GO:1903317 150 0.469
establishment of cell polarity GO:0030010 22 0.469
cell cell signaling GO:0007267 155 0.462
cytoplasmic transport GO:0016482 379 0.460
phospholipid catabolic process GO:0009395 12 0.455
cell projection morphogenesis GO:0048858 129 0.455
regulation of postsynaptic membrane potential GO:0060078 1 0.451
positive regulation of transferase activity GO:0051347 227 0.451
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.444
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.441
cellular metal ion homeostasis GO:0006875 146 0.440
regulation of secretion by cell GO:1903530 177 0.438
regulation of protein polymerization GO:0032271 63 0.435
cellular response to organonitrogen compound GO:0071417 124 0.435
defense response GO:0006952 315 0.431
regulation of neurotransmitter levels GO:0001505 15 0.431
cytokine mediated signaling pathway GO:0019221 109 0.425
positive regulation of monooxygenase activity GO:0032770 14 0.421
small molecule biosynthetic process GO:0044283 157 0.420
generation of precursor metabolites and energy GO:0006091 68 0.418
positive regulation of cell differentiation GO:0045597 211 0.415
forebrain development GO:0030900 26 0.414
carbohydrate biosynthetic process GO:0016051 42 0.414
peptidyl threonine phosphorylation GO:0018107 41 0.413
aspartate transport GO:0015810 5 0.410
regulation of intracellular transport GO:0032386 195 0.406
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.404
vesicle mediated transport GO:0016192 371 0.401
negative regulation of proteolysis GO:0045861 132 0.399
regulation of monooxygenase activity GO:0032768 22 0.395
response to abiotic stimulus GO:0009628 336 0.395
positive regulation of nervous system development GO:0051962 54 0.394
response to light stimulus GO:0009416 87 0.391
positive regulation of hydrolase activity GO:0051345 331 0.389
sulfur compound metabolic process GO:0006790 101 0.389
nucleotide biosynthetic process GO:0009165 109 0.388
regulation of metal ion transport GO:0010959 120 0.386
camp biosynthetic process GO:0006171 47 0.386
cellular macromolecular complex assembly GO:0034622 324 0.383
monocarboxylic acid metabolic process GO:0032787 185 0.381
reactive oxygen species metabolic process GO:0072593 75 0.381
purine ribonucleoside metabolic process GO:0046128 437 0.378
calcium ion transport GO:0006816 147 0.377
protein maturation GO:0051604 233 0.373
negative regulation of neuron apoptotic process GO:0043524 23 0.372
positive regulation of organelle organization GO:0010638 195 0.370
cell adhesion GO:0007155 325 0.368
regulation of cell activation GO:0050865 125 0.368
neurotransmitter transport GO:0006836 10 0.366
regulation of lipase activity GO:0060191 37 0.365
negative regulation of amine transport GO:0051953 1 0.363
regulation of purine nucleotide metabolic process GO:1900542 264 0.363
ribose phosphate biosynthetic process GO:0046390 82 0.362
calcium ion transport into cytosol GO:0060402 48 0.357
regulation of neuron death GO:1901214 56 0.352
protein processing GO:0016485 226 0.352
purine nucleoside triphosphate metabolic process GO:0009144 412 0.352
fatty acid metabolic process GO:0006631 115 0.342
cellular response to hormone stimulus GO:0032870 125 0.342
negative regulation of cellular protein metabolic process GO:0032269 353 0.341
negative regulation of catalytic activity GO:0043086 335 0.341
oocyte development GO:0048599 1 0.340
response to lithium ion GO:0010226 2 0.338
regulation of cellular component biogenesis GO:0044087 281 0.338
negative regulation of protein maturation GO:1903318 142 0.336
response to inorganic substance GO:0010035 127 0.330
maintenance of location GO:0051235 112 0.329
synaptic vesicle endocytosis GO:0048488 2 0.328
positive regulation of gliogenesis GO:0014015 4 0.327
negative regulation of lipid catabolic process GO:0050995 9 0.327
response to interleukin 1 GO:0070555 47 0.326
response to metal ion GO:0010038 84 0.325
innate immune response GO:0045087 178 0.324
organic hydroxy compound transport GO:0015850 63 0.323
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.323
oocyte differentiation GO:0009994 2 0.322
pattern specification process GO:0007389 43 0.319
telencephalon development GO:0021537 17 0.319
divalent metal ion transport GO:0070838 152 0.318
positive regulation of cellular carbohydrate metabolic process GO:0010676 16 0.317
negative regulation of transport GO:0051051 176 0.317
Mouse
microtubule bundle formation GO:0001578 15 0.311
positive regulation of cellular component movement GO:0051272 181 0.311
neuron death GO:0070997 65 0.310
monosaccharide transport GO:0015749 32 0.309
response to hydrogen peroxide GO:0042542 40 0.308
cellular response to hydrogen peroxide GO:0070301 37 0.307
glucose import GO:0046323 24 0.305
mitochondrion organization GO:0007005 156 0.303
second messenger mediated signaling GO:0019932 78 0.302
single organism reproductive process GO:0044702 98 0.301
sulfur compound biosynthetic process GO:0044272 38 0.296
regulation of secretion GO:0051046 194 0.296
small molecule catabolic process GO:0044282 92 0.294
positive regulation of lipid metabolic process GO:0045834 50 0.293
cellular lipid metabolic process GO:0044255 303 0.292
response to molecule of bacterial origin GO:0002237 82 0.292
regulation of map kinase activity GO:0043405 108 0.292
response to biotic stimulus GO:0009607 276 0.291
regulation of cellular response to stress GO:0080135 244 0.291
negative regulation of secretion GO:0051048 58 0.290
positive regulation of neurogenesis GO:0050769 49 0.290
ribonucleoside triphosphate metabolic process GO:0009199 412 0.286
regulation of protein catabolic process GO:0042176 155 0.286
neuromuscular junction development GO:0007528 3 0.284
dicarboxylic acid transport GO:0006835 13 0.283
histone acetylation GO:0016573 93 0.282
regulation of cell development GO:0060284 161 0.282
positive regulation of cell cycle GO:0045787 140 0.280
cellular cation homeostasis GO:0030003 163 0.278
regulation of cytoskeleton organization GO:0051493 177 0.276
regulation of glucose transport GO:0010827 23 0.276
nucleoside triphosphate metabolic process GO:0009141 422 0.274
cation transmembrane transport GO:0098655 238 0.271
serotonin transport GO:0006837 3 0.270
regulation of calcium ion transport into cytosol GO:0010522 33 0.268
positive regulation of cell growth GO:0030307 48 0.266
mitochondrial membrane organization GO:0007006 40 0.264
determination of adult lifespan GO:0008340 2 0.261
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.259
internal peptidyl lysine acetylation GO:0018393 97 0.258
oxidation reduction process GO:0055114 396 0.258
regulation of catecholamine secretion GO:0050433 1 0.255
regulation of protein localization to nucleus GO:1900180 85 0.254
negative regulation of cell death GO:0060548 345 0.254
energy derivation by oxidation of organic compounds GO:0015980 43 0.253
organelle localization GO:0051640 84 0.253
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.253
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.252
cation homeostasis GO:0055080 189 0.251
synaptic vesicle transport GO:0048489 5 0.251
memory GO:0007613 3 0.248
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.247
regulation of reactive oxygen species metabolic process GO:2000377 41 0.245
reactive nitrogen species metabolic process GO:2001057 3 0.244
organic hydroxy compound biosynthetic process GO:1901617 71 0.239
tor signaling GO:0031929 39 0.238
taxis GO:0042330 157 0.238
peptidyl tyrosine phosphorylation GO:0018108 170 0.235
regulation of anoikis GO:2000209 19 0.233
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.231
regulation of protein kinase activity GO:0045859 289 0.231
lipid localization GO:0010876 106 0.230
leukocyte activation GO:0045321 164 0.228
phospholipid metabolic process GO:0006644 99 0.228
ethanolamine containing compound metabolic process GO:0042439 26 0.226
myeloid leukocyte activation GO:0002274 34 0.226
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.225
positive regulation of intracellular protein transport GO:0090316 76 0.225
synaptic vesicle localization GO:0097479 5 0.224
glucose transport GO:0015758 30 0.224
regulation of cell growth GO:0001558 135 0.223
post embryonic development GO:0009791 2 0.222
regulation of dendrite development GO:0050773 18 0.221
response to peptide GO:1901652 65 0.220
negative regulation of organelle organization GO:0010639 126 0.218
purine containing compound biosynthetic process GO:0072522 88 0.218
regulation of protein processing GO:0070613 150 0.216
regulation of protein complex assembly GO:0043254 147 0.216
regulation of cell cycle GO:0051726 393 0.216
signal release GO:0023061 70 0.211
regulation of ion homeostasis GO:2000021 73 0.211
positive regulation of secretion by cell GO:1903532 108 0.210
response to growth factor GO:0070848 205 0.209
regulation of response to oxidative stress GO:1902882 26 0.206
ribonucleotide catabolic process GO:0009261 405 0.206
negative regulation of hydrolase activity GO:0051346 182 0.205
regulation of cytoplasmic transport GO:1903649 149 0.205
regulation of lipid catabolic process GO:0050994 23 0.204
regulation of peptidyl serine phosphorylation GO:0033135 50 0.204
response to reactive oxygen species GO:0000302 61 0.204
coenzyme biosynthetic process GO:0009108 24 0.199
vascular process in circulatory system GO:0003018 29 0.199
signal transduction by phosphorylation GO:0023014 297 0.197
neurological system process GO:0050877 163 0.197
cellular homeostasis GO:0019725 196 0.196
mapk cascade GO:0000165 288 0.196
sequestering of metal ion GO:0051238 24 0.195
cardiovascular system development GO:0072358 262 0.195
regulation of cell migration GO:0030334 289 0.195
regulation of anatomical structure size GO:0090066 101 0.194
ion homeostasis GO:0050801 230 0.194
purine containing compound catabolic process GO:0072523 411 0.193
purine nucleoside monophosphate metabolic process GO:0009126 186 0.191
cofactor biosynthetic process GO:0051188 31 0.191
regeneration GO:0031099 4 0.190
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.190
anatomical structure formation involved in morphogenesis GO:0048646 284 0.189
neuron neuron synaptic transmission GO:0007270 6 0.188
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.188
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.188
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.186
response to wounding GO:0009611 168 0.186
positive regulation of cell migration GO:0030335 172 0.186
regulation of synaptic transmission dopaminergic GO:0032225 4 0.186
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.185
regulation of neuronal synaptic plasticity GO:0048168 1 0.183
calcium ion homeostasis GO:0055074 122 0.182
positive regulation of protein kinase activity GO:0045860 190 0.181
peptidyl lysine modification GO:0018205 144 0.179
histone h2a s1 phosphorylation GO:0043990 1 0.179
negative regulation of protein phosphorylation GO:0001933 140 0.178
regulation of autophagy GO:0010506 52 0.176
response to mechanical stimulus GO:0009612 51 0.175
positive regulation of glial cell proliferation GO:0060252 2 0.174
embryo development GO:0009790 123 0.172
developmental growth GO:0048589 48 0.172
single organism behavior GO:0044708 28 0.172
Mouse
regulation of macrophage chemotaxis GO:0010758 4 0.170
negative regulation of phosphorus metabolic process GO:0010563 267 0.170
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.170
negative regulation of protein modification process GO:0031400 200 0.170
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.170
positive regulation of cellular protein catabolic process GO:1903364 37 0.168
cofactor metabolic process GO:0051186 87 0.166
regulation of epithelial cell migration GO:0010632 93 0.165
dopamine biosynthetic process GO:0042416 4 0.165
protein polymerization GO:0051258 71 0.163
negative regulation of phosphate metabolic process GO:0045936 267 0.162
synaptic transmission GO:0007268 61 0.161
divalent inorganic cation transport GO:0072511 158 0.161
catecholamine uptake involved in synaptic transmission GO:0051934 4 0.161
norepinephrine transport GO:0015874 1 0.161
cellular chemical homeostasis GO:0055082 180 0.160
purine ribonucleoside catabolic process GO:0046130 398 0.159
regulation of endothelial cell migration GO:0010594 67 0.159
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.157
cellular divalent inorganic cation homeostasis GO:0072503 128 0.155
positive regulation of neurotransmitter transport GO:0051590 1 0.155
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.153
segmentation GO:0035282 4 0.152
l glutamate import GO:0051938 3 0.152
nucleocytoplasmic transport GO:0006913 176 0.151
regulation of exocytosis GO:0017157 46 0.150
response to other organism GO:0051707 261 0.150
protein localization to membrane GO:0072657 160 0.150
peptidyl lysine acetylation GO:0018394 101 0.149
response to radiation GO:0009314 151 0.149
cellular response to dna damage stimulus GO:0006974 379 0.148
positive regulation of map kinase activity GO:0043406 80 0.146
somatic muscle development GO:0007525 1 0.145
epithelium migration GO:0090132 119 0.145
negative regulation of multicellular organismal process GO:0051241 317 0.145
regulation of dopamine uptake involved in synaptic transmission GO:0051584 4 0.145
establishment of organelle localization GO:0051656 59 0.144
Mouse
response to lipopolysaccharide GO:0032496 70 0.144
positive regulation of nucleotide metabolic process GO:0045981 230 0.144
peripheral nervous system development GO:0007422 2 0.143
single organism cell adhesion GO:0098602 179 0.143
release of sequestered calcium ion into cytosol GO:0051209 41 0.142
response to organic cyclic compound GO:0014070 204 0.141
positive regulation of proteolysis GO:0045862 142 0.141
negative regulation of neuron death GO:1901215 32 0.140
regulation of transmembrane transporter activity GO:0022898 74 0.140
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.140
positive regulation of secretion GO:0051047 116 0.139
developmental process involved in reproduction GO:0003006 66 0.139
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.138
autophagy GO:0006914 88 0.138
protein acetylation GO:0006473 116 0.137
cerebral cortex development GO:0021987 10 0.137
peptidyl tyrosine modification GO:0018212 170 0.137
hexose transport GO:0008645 30 0.136
neuron apoptotic process GO:0051402 39 0.135
reactive oxygen species biosynthetic process GO:1903409 4 0.133
translation GO:0006412 132 0.132
positive regulation of homeostatic process GO:0032846 47 0.132
ionotropic glutamate receptor signaling pathway GO:0035235 16 0.132
positive regulation of phospholipid transport GO:2001140 4 0.132
positive regulation of gtpase activity GO:0043547 166 0.131
regulation of carbohydrate biosynthetic process GO:0043255 27 0.131
receptor mediated endocytosis GO:0006898 84 0.127
acid secretion GO:0046717 12 0.127
cellular macromolecule catabolic process GO:0044265 380 0.126
nuclear import GO:0051170 106 0.126
regulation of phospholipid transport GO:2001138 4 0.125
regulation of glial cell proliferation GO:0060251 4 0.125
purine ribonucleotide catabolic process GO:0009154 404 0.125
cellular response to peptide GO:1901653 59 0.124
cellular response to organic cyclic compound GO:0071407 127 0.124
lipid catabolic process GO:0016042 84 0.124
regulation of cell motility GO:2000145 299 0.123
regulation of neurotransmitter transport GO:0051588 7 0.123
hindbrain development GO:0030902 3 0.122
right ventricular cardiac muscle tissue morphogenesis GO:0003221 2 0.121
nucleoside monophosphate metabolic process GO:0009123 191 0.120
alcohol biosynthetic process GO:0046165 52 0.120
calcium mediated signaling GO:0019722 44 0.120
cell activation GO:0001775 213 0.120
regulation of neuron apoptotic process GO:0043523 35 0.119
circulatory system process GO:0003013 113 0.118
regulation of lipid biosynthetic process GO:0046890 47 0.117
catecholamine secretion GO:0050432 1 0.117
mitotic cell cycle process GO:1903047 286 0.117
negative regulation of synaptic transmission dopaminergic GO:0032227 1 0.116
positive regulation of lipid biosynthetic process GO:0046889 22 0.116
atp metabolic process GO:0046034 176 0.116
negative regulation of lipid transport GO:0032369 18 0.116
cellular response to ammonium ion GO:0071242 4 0.116
cellular protein catabolic process GO:0044257 261 0.115

MAPT disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.889
nervous system disease DOID:863 431 0.889
neurodegenerative disease DOID:1289 102 0.782
disease of mental health DOID:150 70 0.446
parkinson s disease DOID:14330 18 0.286
synucleinopathy DOID:0050890 22 0.286