Homo sapiens

0 known processes

MARCH7

membrane-associated ring finger (C3HC4) 7

(Aliases: DKFZp586F1122,AXOT,RNF177,AXO,MARCH-VII)

MARCH7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein polyubiquitination GO:0000209 110 0.995
protein modification by small protein conjugation GO:0032446 342 0.994
protein ubiquitination GO:0016567 314 0.985
modification dependent macromolecule catabolic process GO:0043632 212 0.925
ubiquitin dependent protein catabolic process GO:0006511 206 0.893
protein k48 linked ubiquitination GO:0070936 38 0.870
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.868
cellular protein catabolic process GO:0044257 261 0.792
histone ubiquitination GO:0016574 31 0.766
modification dependent protein catabolic process GO:0019941 209 0.698
protein catabolic process GO:0030163 325 0.633
protein autoubiquitination GO:0051865 37 0.584
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.497
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.428
cellular macromolecule catabolic process GO:0044265 380 0.389
protein monoubiquitination GO:0006513 39 0.376
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.308
cellular macromolecular complex assembly GO:0034622 324 0.280
protein k63 linked ubiquitination GO:0070534 31 0.269
regulation of cellular response to stress GO:0080135 244 0.238
positive regulation of cellular component organization GO:0051130 376 0.212
histone modification GO:0016570 251 0.167
chromatin organization GO:0006325 351 0.162
interspecies interaction between organisms GO:0044419 156 0.159
chromatin modification GO:0016568 298 0.156
mitotic cell cycle GO:0000278 326 0.150
positive regulation of organelle organization GO:0010638 195 0.147
cellular response to dna damage stimulus GO:0006974 379 0.144
maintenance of location GO:0051235 112 0.118
regulation of proteolysis GO:0030162 293 0.117
regulation of cell cycle GO:0051726 393 0.117
oocyte differentiation GO:0009994 2 0.109
proteasomal protein catabolic process GO:0010498 176 0.108
cellular protein complex assembly GO:0043623 188 0.106
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.104
nervous system development GO:0007399 293 0.101
actin filament based process GO:0030029 224 0.098
regulation of proteasomal protein catabolic process GO:0061136 87 0.098
neuromuscular junction development GO:0007528 3 0.094
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.092
negative regulation of protein metabolic process GO:0051248 391 0.089
regulation of dna metabolic process GO:0051052 153 0.088
cellular amino acid metabolic process GO:0006520 116 0.087
maintenance of protein location GO:0045185 57 0.086
post embryonic development GO:0009791 2 0.083
cell development GO:0048468 328 0.082
positive regulation of developmental process GO:0051094 314 0.078
viral release from host cell GO:0019076 21 0.078
regulation of response to dna damage stimulus GO:2001020 94 0.075
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.075
response to abiotic stimulus GO:0009628 336 0.070
ribonucleoside monophosphate metabolic process GO:0009161 187 0.069
covalent chromatin modification GO:0016569 254 0.069
amine metabolic process GO:0009308 44 0.066
regulation of cell cycle process GO:0010564 266 0.066
female gamete generation GO:0007292 2 0.066
oocyte development GO:0048599 1 0.062
cell projection organization GO:0030030 252 0.062
actin cytoskeleton organization GO:0030036 207 0.062
cation transport GO:0006812 331 0.062
negative regulation of cellular protein metabolic process GO:0032269 353 0.061
negative regulation of immune system process GO:0002683 136 0.061
Mouse
dephosphorylation GO:0016311 209 0.061
regulation of chromosome organization GO:0033044 103 0.059
histone h2a ubiquitination GO:0033522 17 0.059
regulation of protein processing GO:0070613 150 0.056
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.054
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.054
immune effector process GO:0002252 159 0.054
positive regulation of cell death GO:0010942 263 0.053
positive regulation of protein ubiquitination GO:0031398 53 0.052
regulation of mitotic cell cycle phase transition GO:1901990 118 0.049
response to transforming growth factor beta GO:0071559 94 0.047
neurogenesis GO:0022008 169 0.046
cell cycle checkpoint GO:0000075 117 0.046
regulation of dna repair GO:0006282 47 0.045
oogenesis GO:0048477 2 0.044
nitrogen compound transport GO:0071705 191 0.044
dna integrity checkpoint GO:0031570 71 0.043
immune response GO:0006955 307 0.043
protein localization to organelle GO:0033365 280 0.043
cellular ketone metabolic process GO:0042180 80 0.042
regulation of cellular ketone metabolic process GO:0010565 50 0.041
regulation of kinase activity GO:0043549 314 0.041
maintenance of protein location in cell GO:0032507 56 0.041
rna processing GO:0006396 255 0.040
neuron development GO:0048666 113 0.040
response to growth factor GO:0070848 205 0.040
mitotic cell cycle process GO:1903047 286 0.040
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.039
cell cycle phase transition GO:0044770 173 0.038
segmentation GO:0035282 4 0.037
regulation of protein stability GO:0031647 87 0.037
positive regulation of transferase activity GO:0051347 227 0.037
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.037
secretion by cell GO:0032940 226 0.037
negative regulation of cell death GO:0060548 345 0.036
dna repair GO:0006281 198 0.036
cellular component morphogenesis GO:0032989 314 0.036
cellular response to endogenous stimulus GO:0071495 336 0.035
vesicle organization GO:0016050 62 0.035
regulation of protein catabolic process GO:0042176 155 0.035
microtubule cytoskeleton organization GO:0000226 176 0.035
chordate embryonic development GO:0043009 34 0.035
metal ion transport GO:0030001 272 0.034
peptidyl serine phosphorylation GO:0018105 101 0.034
organelle fission GO:0048285 149 0.034
ribonucleoside monophosphate catabolic process GO:0009158 158 0.034
protein dephosphorylation GO:0006470 81 0.033
lymphocyte activation GO:0046649 133 0.033
Mouse
regulation of intracellular transport GO:0032386 195 0.033
embryo development GO:0009790 123 0.033
microtubule organizing center organization GO:0031023 62 0.033
positive regulation of cellular amine metabolic process GO:0033240 7 0.033
regulation of chromatin modification GO:1903308 51 0.033
negative regulation of hydrolase activity GO:0051346 182 0.033
positive regulation of immune system process GO:0002684 283 0.033
protein processing GO:0016485 226 0.032
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.032
negative regulation of apoptotic process GO:0043066 316 0.032
response to cytokine GO:0034097 232 0.032
morphogenesis of embryonic epithelium GO:0016331 4 0.032
regulation of protein complex assembly GO:0043254 147 0.031
positive regulation of proteolysis GO:0045862 142 0.031
regulation of protein polymerization GO:0032271 63 0.031
stress activated mapk cascade GO:0051403 93 0.030
neural tube formation GO:0001841 3 0.030
regulation of secretion by cell GO:1903530 177 0.029
chromosome segregation GO:0007059 114 0.029
atp catabolic process GO:0006200 157 0.029
metencephalon development GO:0022037 2 0.028
positive regulation of programmed cell death GO:0043068 249 0.028
response to hormone GO:0009725 175 0.028
cellular response to growth factor stimulus GO:0071363 197 0.028
posttranscriptional regulation of gene expression GO:0010608 213 0.028
regulation of cell cycle phase transition GO:1901987 126 0.028
vesicle mediated transport GO:0016192 371 0.028
cell morphogenesis GO:0000902 296 0.027
negative regulation of secretion by cell GO:1903531 52 0.027
histone monoubiquitination GO:0010390 20 0.027
negative regulation of organelle organization GO:0010639 126 0.027
regulation of cellular protein catabolic process GO:1903362 96 0.026
regulation of protein maturation GO:1903317 150 0.026
protein maturation GO:0051604 233 0.026
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.026
endomembrane system organization GO:0010256 196 0.026
negative regulation of cellular component organization GO:0051129 235 0.025
negative regulation of protein maturation GO:1903318 142 0.025
inner ear morphogenesis GO:0042472 4 0.025
macromolecule methylation GO:0043414 97 0.025
cellular homeostasis GO:0019725 196 0.025
regulation of protein ubiquitination GO:0031396 95 0.025
mitotic cell cycle checkpoint GO:0007093 68 0.025
blastocyst formation GO:0001825 3 0.025
t cell activation GO:0042110 99 0.024
Mouse
regulation of cellular component biogenesis GO:0044087 281 0.024
positive regulation of cellular component biogenesis GO:0044089 158 0.024
negative regulation of chromosome organization GO:2001251 48 0.024
nucleoside monophosphate metabolic process GO:0009123 191 0.024
regulation of rna splicing GO:0043484 62 0.024
neuron differentiation GO:0030182 138 0.024
positive regulation of transport GO:0051050 336 0.024
protein polymerization GO:0051258 71 0.023
centrosome organization GO:0051297 58 0.023
embryonic organ morphogenesis GO:0048562 24 0.023
anatomical structure formation involved in morphogenesis GO:0048646 284 0.023
regulation of secretion GO:0051046 194 0.023
regulation of cytoskeleton organization GO:0051493 177 0.023
regulation of homeostatic process GO:0032844 121 0.023
negative regulation of transport GO:0051051 176 0.023
hindbrain development GO:0030902 3 0.022
hormone secretion GO:0046879 65 0.022
canonical wnt signaling pathway GO:0060070 116 0.022
cellular amine metabolic process GO:0044106 41 0.022
positive regulation of phosphorylation GO:0042327 394 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
pattern specification process GO:0007389 43 0.022
response to other organism GO:0051707 261 0.022
dna conformation change GO:0071103 113 0.021
double strand break repair GO:0006302 101 0.021
neurological system process GO:0050877 163 0.021
mitotic cell cycle phase transition GO:0044772 162 0.021
regulation of anatomical structure size GO:0090066 101 0.021
hormone transport GO:0009914 68 0.021
negative regulation of secretion GO:0051048 58 0.021
negative regulation of peptidase activity GO:0010466 91 0.021
androgen receptor signaling pathway GO:0030521 34 0.021
negative regulation of cell cycle phase transition GO:1901988 89 0.021
peptide transport GO:0015833 74 0.021
regulation of transferase activity GO:0051338 355 0.021
single organism cellular localization GO:1902580 332 0.020
lipid localization GO:0010876 106 0.020
regulation of mitotic cell cycle GO:0007346 189 0.020
negative regulation of cell differentiation GO:0045596 171 0.020
membrane organization GO:0061024 292 0.020
regulation of vesicle mediated transport GO:0060627 130 0.020
negative regulation of cell cycle GO:0045786 193 0.020
regulation of canonical wnt signaling pathway GO:0060828 88 0.019
purine nucleotide catabolic process GO:0006195 405 0.019
regulation of cell division GO:0051302 116 0.019
peptidyl tyrosine phosphorylation GO:0018108 170 0.019
response to oxygen containing compound GO:1901700 369 0.019
positive regulation of cell differentiation GO:0045597 211 0.019
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.019
long term memory GO:0007616 2 0.019
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.019
maintenance of location in cell GO:0051651 62 0.019
organophosphate biosynthetic process GO:0090407 163 0.018
cell morphogenesis involved in differentiation GO:0000904 144 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
amide transport GO:0042886 76 0.018
anterior posterior axis specification GO:0009948 2 0.018
endocytosis GO:0006897 159 0.018
chemotaxis GO:0006935 157 0.018
response to radiation GO:0009314 151 0.018
positive regulation of growth GO:0045927 58 0.018
protein dna complex subunit organization GO:0071824 80 0.018
small molecule biosynthetic process GO:0044283 157 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
regulation of histone modification GO:0031056 47 0.018
negative regulation of developmental process GO:0051093 247 0.017
negative regulation of cell proliferation GO:0008285 228 0.017
Mouse
regulation of growth GO:0040008 165 0.017
negative regulation of protein phosphorylation GO:0001933 140 0.017
negative regulation of chromatin modification GO:1903309 21 0.017
regulation of cytoplasmic transport GO:1903649 149 0.017
cell activation GO:0001775 213 0.017
Mouse
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
i kappab kinase nf kappab signaling GO:0007249 166 0.017
regulation of jnk cascade GO:0046328 73 0.017
regulation of actin filament length GO:0030832 56 0.016
neuroblast proliferation GO:0007405 4 0.016
generation of neurons GO:0048699 152 0.016
apoptotic signaling pathway GO:0097190 268 0.016
determination of adult lifespan GO:0008340 2 0.016
cell growth GO:0016049 160 0.016
positive regulation of protein phosphorylation GO:0001934 313 0.016
purine nucleoside monophosphate catabolic process GO:0009128 158 0.016
atp metabolic process GO:0046034 176 0.016
primary neural tube formation GO:0014020 3 0.016
regulation of cellular amine metabolic process GO:0033238 11 0.016
skeletal system development GO:0001501 79 0.016
positive regulation of dna metabolic process GO:0051054 73 0.016
regulation of leukocyte differentiation GO:1902105 61 0.016
single organism membrane organization GO:0044802 268 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.015
glycoprotein metabolic process GO:0009100 110 0.015
positive regulation of immune response GO:0050778 159 0.015
tube development GO:0035295 125 0.015
regulation of chromatin organization GO:1902275 56 0.015
microtubule based process GO:0007017 210 0.015
golgi vesicle transport GO:0048193 80 0.015
protein stabilization GO:0050821 64 0.015
leukocyte mediated immunity GO:0002443 59 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
regulation of cellular amino acid metabolic process GO:0006521 6 0.014
negative regulation of endopeptidase activity GO:0010951 84 0.014
protein dna complex assembly GO:0065004 64 0.014
peptide secretion GO:0002790 51 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.014
meiotic chromosome segregation GO:0045132 4 0.014
defense response GO:0006952 315 0.014
purine ribonucleoside metabolic process GO:0046128 437 0.014
growth GO:0040007 202 0.014
lipid metabolic process GO:0006629 381 0.014
negative regulation of proteolysis GO:0045861 132 0.014
positive regulation of histone modification GO:0031058 29 0.014
response to extracellular stimulus GO:0009991 85 0.014
positive regulation of chromosome organization GO:2001252 41 0.013
stem cell division GO:0017145 2 0.013
response to nutrient levels GO:0031667 81 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.013
regulation of response to external stimulus GO:0032101 222 0.013
wnt signaling pathway GO:0016055 156 0.013
protein oligomerization GO:0051259 173 0.013
peptide hormone secretion GO:0030072 50 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
embryonic camera type eye morphogenesis GO:0048596 2 0.013
notch signaling pathway GO:0007219 31 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
regulation of protein kinase activity GO:0045859 289 0.013
positive regulation of sequestering of triglyceride GO:0010890 3 0.013
tube closure GO:0060606 3 0.013
regulation of immune response GO:0050776 201 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
cell division GO:0051301 168 0.013
cellular response to oxygen levels GO:0071453 55 0.012
positive regulation of response to external stimulus GO:0032103 88 0.012
mrna metabolic process GO:0016071 175 0.012
somitogenesis GO:0001756 2 0.012
cardiovascular system development GO:0072358 262 0.012
spermatid development GO:0007286 4 0.012
regulation of ubiquitin protein transferase activity GO:0051438 28 0.012
neural tube closure GO:0001843 3 0.012
response to ionizing radiation GO:0010212 65 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
negative regulation of transferase activity GO:0051348 124 0.012
regulation of multi organism process GO:0043900 157 0.012
cellular response to lipid GO:0071396 127 0.012
locomotory behavior GO:0007626 1 0.012
regulation of cell differentiation GO:0045595 393 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.012
heart morphogenesis GO:0003007 48 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.012
memory GO:0007613 3 0.012
regulation of hormone levels GO:0010817 125 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
regulation of immune effector process GO:0002697 91 0.012
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.012
response to peptide hormone GO:0043434 61 0.012
positive regulation of viral process GO:0048524 37 0.011
positive regulation of mitotic cell cycle GO:0045931 60 0.011
cell part morphogenesis GO:0032990 137 0.011
dna damage checkpoint GO:0000077 68 0.011
head development GO:0060322 108 0.011
regulation of growth rate GO:0040009 1 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
regulation of actin filament polymerization GO:0030833 50 0.011
stem cell development GO:0048864 69 0.011
regulation of defense response GO:0031347 154 0.010
cell adhesion GO:0007155 325 0.010
actin filament polymerization GO:0030041 45 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.010
chemical homeostasis GO:0048878 306 0.010
neutrophil degranulation GO:0043312 3 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010
cellular response to cytokine stimulus GO:0071345 181 0.010
calcium ion transport GO:0006816 147 0.010
peptidyl serine modification GO:0018209 106 0.010

MARCH7 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.077
eye and adnexa disease DOID:1492 150 0.077
nervous system disease DOID:863 431 0.077
eye disease DOID:5614 149 0.077
cancer DOID:162 167 0.022
disease of cellular proliferation DOID:14566 174 0.022
organ system cancer DOID:0050686 164 0.022