Homo sapiens

90 known processes

MARK2

MAP/microtubule affinity-regulating kinase 2

(Aliases: Par1b,EMK-1,MGC99619,EMK1,PAR-1)

MARK2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.858
regulation of cell development GO:0060284 161 0.817
cell development GO:0048468 328 0.815
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.812
neuronal stem cell division GO:0036445 1 0.793
Worm
positive regulation of phosphorylation GO:0042327 394 0.767
regulation of cellular amine metabolic process GO:0033238 11 0.715
single organism cellular localization GO:1902580 332 0.707
regulation of neurogenesis GO:0050767 82 0.659
regulation of cell differentiation GO:0045595 393 0.625
regulation of cytokine production GO:0001817 232 0.612
positive regulation of protein phosphorylation GO:0001934 313 0.593
asymmetric neuroblast division GO:0055059 1 0.589
Worm
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.575
cell fate determination GO:0001709 3 0.573
Worm
neuroblast division GO:0055057 1 0.566
Worm
generation of neurons GO:0048699 152 0.556
positive regulation of cellular amine metabolic process GO:0033240 7 0.499
establishment of cell polarity GO:0030010 22 0.492
positive regulation of transferase activity GO:0051347 227 0.490
cell projection organization GO:0030030 252 0.476
cellular ketone metabolic process GO:0042180 80 0.464
neuron projection development GO:0031175 106 0.441
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.441
ras protein signal transduction GO:0007265 73 0.440
regulation of neuron projection development GO:0010975 57 0.437
nervous system development GO:0007399 293 0.429
regulation of cellular ketone metabolic process GO:0010565 50 0.416
organophosphate catabolic process GO:0046434 430 0.407
vesicle mediated transport GO:0016192 371 0.400
regulation of cell projection organization GO:0031344 107 0.384
transmembrane transport GO:0055085 399 0.382
cellular amine metabolic process GO:0044106 41 0.377
post embryonic development GO:0009791 2 0.375
Worm
growth GO:0040007 202 0.375
endomembrane system organization GO:0010256 196 0.369
small gtpase mediated signal transduction GO:0007264 78 0.363
anterior posterior axis specification GO:0009948 2 0.362
regulation of cell morphogenesis GO:0022604 153 0.361
cell morphogenesis GO:0000902 296 0.359
cellular component disassembly GO:0022411 92 0.353
sodium ion transport GO:0006814 61 0.343
microtubule cytoskeleton organization GO:0000226 176 0.343
Human
regulation of microtubule based process GO:0032886 74 0.343
amine metabolic process GO:0009308 44 0.339
positive regulation of catabolic process GO:0009896 310 0.332
nucleoside catabolic process GO:0009164 408 0.329
regulation of nervous system development GO:0051960 88 0.324
cellular amino acid metabolic process GO:0006520 116 0.319
regulation of anatomical structure morphogenesis GO:0022603 286 0.316
establishment of organelle localization GO:0051656 59 0.309
peptidyl tyrosine modification GO:0018212 170 0.309
ribonucleoside catabolic process GO:0042454 406 0.306
response to muramyl dipeptide GO:0032495 4 0.301
apoptotic signaling pathway GO:0097190 268 0.299
regulation of ion transmembrane transport GO:0034765 132 0.296
ribonucleotide catabolic process GO:0009261 405 0.290
organelle localization GO:0051640 84 0.278
nucleoside triphosphate metabolic process GO:0009141 422 0.276
somatic stem cell division GO:0048103 1 0.276
Worm
purine ribonucleoside metabolic process GO:0046128 437 0.271
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.270
regulation of proteolysis GO:0030162 293 0.262
purine ribonucleotide catabolic process GO:0009154 404 0.252
mitotic cell cycle process GO:1903047 286 0.249
microtubule based process GO:0007017 210 0.248
Human
cell division GO:0051301 168 0.246
Worm
positive regulation of protein kinase activity GO:0045860 190 0.245
ribonucleoside triphosphate metabolic process GO:0009199 412 0.242
establishment of mitotic spindle orientation GO:0000132 7 0.242
establishment or maintenance of cell polarity GO:0007163 31 0.238
purine containing compound catabolic process GO:0072523 411 0.234
positive regulation of ras gtpase activity GO:0032320 117 0.232
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.230
positive regulation of rac gtpase activity GO:0032855 31 0.227
regulation of protein localization GO:0032880 296 0.225
nucleoside phosphate catabolic process GO:1901292 412 0.221
purine ribonucleoside catabolic process GO:0046130 398 0.220
regulation of cell motility GO:2000145 299 0.218
signal transduction by phosphorylation GO:0023014 297 0.218
negative regulation of protein maturation GO:1903318 142 0.217
positive regulation of anoikis GO:2000210 4 0.213
Human
asymmetric stem cell division GO:0098722 1 0.211
Worm
ribonucleoside triphosphate catabolic process GO:0009203 391 0.210
positive regulation of developmental process GO:0051094 314 0.209
oocyte differentiation GO:0009994 2 0.207
establishment of spindle orientation GO:0051294 9 0.205
regulation of protein kinase activity GO:0045859 289 0.205
purine nucleoside triphosphate metabolic process GO:0009144 412 0.203
cellular response to muramyl dipeptide GO:0071225 3 0.200
cellular protein complex disassembly GO:0043624 36 0.198
regulation of meiotic cell cycle GO:0051445 4 0.195
oocyte development GO:0048599 1 0.195
regulation of mapk cascade GO:0043408 262 0.194
regulation of protein depolymerization GO:1901879 22 0.192
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.192
regulation of small gtpase mediated signal transduction GO:0051056 156 0.191
multicellular organismal aging GO:0010259 3 0.190
neuron differentiation GO:0030182 138 0.189
protein complex disassembly GO:0043241 52 0.188
positive regulation of programmed cell death GO:0043068 249 0.188
Human
inorganic ion transmembrane transport GO:0098660 231 0.187
cation transmembrane transport GO:0098655 238 0.187
protein depolymerization GO:0051261 30 0.186
regulation of rho gtpase activity GO:0032319 66 0.183
female gamete generation GO:0007292 2 0.182
regulation of microtubule cytoskeleton organization GO:0070507 61 0.178
nuclear transport GO:0051169 179 0.177
positive regulation of mapk cascade GO:0043410 190 0.177
activation of protein kinase activity GO:0032147 90 0.176
purine nucleoside catabolic process GO:0006152 398 0.172
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.172
negative regulation of protein metabolic process GO:0051248 391 0.171
mapk cascade GO:0000165 288 0.170
cell part morphogenesis GO:0032990 137 0.167
positive regulation of gtpase activity GO:0043547 166 0.166
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.166
protein dephosphorylation GO:0006470 81 0.165
positive regulation of cell death GO:0010942 263 0.162
Human
sodium ion transmembrane transport GO:0035725 59 0.161
peptidyl serine modification GO:0018209 106 0.158
Worm
rho protein signal transduction GO:0007266 26 0.157
actin cytoskeleton organization GO:0030036 207 0.153
negative regulation of phosphate metabolic process GO:0045936 267 0.152
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.150
cytokine production GO:0001816 247 0.149
cation transport GO:0006812 331 0.147
establishment of spindle localization GO:0051293 12 0.147
positive regulation of hydrolase activity GO:0051345 331 0.147
negative regulation of transport GO:0051051 176 0.147
negative regulation of cellular component organization GO:0051129 235 0.146
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.144
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.141
gtp catabolic process GO:0006184 237 0.141
negative regulation of cell differentiation GO:0045596 171 0.141
regulation of locomotion GO:0040012 329 0.141
establishment of nucleus localization GO:0040023 1 0.141
nucleus localization GO:0051647 1 0.140
positive regulation of apoptotic process GO:0043065 246 0.138
Human
regulation of synaptic plasticity GO:0048167 3 0.137
purine nucleotide catabolic process GO:0006195 405 0.137
regulation of transferase activity GO:0051338 355 0.137
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.135
mitotic cell cycle GO:0000278 326 0.133
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.132
nucleotide catabolic process GO:0009166 408 0.131
negative regulation of developmental process GO:0051093 247 0.131
Worm
macromolecular complex disassembly GO:0032984 60 0.130
protein targeting to nucleus GO:0044744 104 0.130
positive regulation of nucleotide metabolic process GO:0045981 230 0.128
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.128
action potential GO:0001508 34 0.126
dna replication GO:0006260 116 0.126
protein maturation GO:0051604 233 0.124
regulation of kinase activity GO:0043549 314 0.123
positive regulation of p38mapk cascade GO:1900745 8 0.123
neurogenesis GO:0022008 169 0.123
regulation of metal ion transport GO:0010959 120 0.122
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.121
peptidyl tyrosine phosphorylation GO:0018108 170 0.120
positive regulation of cell differentiation GO:0045597 211 0.120
regulation of cytoskeleton organization GO:0051493 177 0.119
Rat
negative regulation of locomotion GO:0040013 118 0.118
regulation of ras protein signal transduction GO:0046578 155 0.117
purine nucleoside triphosphate catabolic process GO:0009146 392 0.117
intracellular protein transport GO:0006886 270 0.116
regulation of endopeptidase activity GO:0052548 170 0.116
dephosphorylation GO:0016311 209 0.116
gtp metabolic process GO:0046039 239 0.115
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.114
cellular macromolecule catabolic process GO:0044265 380 0.112
microtubule polymerization or depolymerization GO:0031109 37 0.111
ion transmembrane transport GO:0034220 338 0.111
single organism carbohydrate metabolic process GO:0044723 193 0.111
cytoplasmic transport GO:0016482 379 0.110
regulation of transporter activity GO:0032409 82 0.110
cellular response to nitrogen compound GO:1901699 144 0.110
negative regulation of protein complex disassembly GO:0043242 20 0.109
cellular component morphogenesis GO:0032989 314 0.109
system process GO:0003008 349 0.109
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.108
regulation of purine nucleotide catabolic process GO:0033121 205 0.108
vesicle organization GO:0016050 62 0.108
regulation of nucleotide catabolic process GO:0030811 205 0.107
cellular potassium ion transport GO:0071804 60 0.107
regulation of protein serine threonine kinase activity GO:0071900 179 0.106
nucleoside triphosphate catabolic process GO:0009143 394 0.106
negative regulation of cellular protein metabolic process GO:0032269 353 0.106
positive regulation of cellular catabolic process GO:0031331 284 0.105
regulation of protein transport GO:0051223 213 0.104
regulation of cellular protein catabolic process GO:1903362 96 0.104
endocytosis GO:0006897 159 0.104
tripartite regional subdivision GO:0007351 2 0.104
inorganic cation transmembrane transport GO:0098662 194 0.102
determination of adult lifespan GO:0008340 2 0.101
positive regulation of kinase activity GO:0033674 204 0.100
neuron development GO:0048666 113 0.098
regulation of protein stability GO:0031647 87 0.098
negative regulation of multicellular organismal process GO:0051241 317 0.097
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.096
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.095
regulation of ion transmembrane transporter activity GO:0032412 72 0.093
cellular response to peptide GO:1901653 59 0.093
actin filament based process GO:0030029 224 0.093
long term memory GO:0007616 2 0.093
nucleoside monophosphate catabolic process GO:0009125 159 0.090
negative regulation of catalytic activity GO:0043086 335 0.090
cellular macromolecular complex assembly GO:0034622 324 0.089
protein localization to membrane GO:0072657 160 0.089
anterior posterior axis specification embryo GO:0008595 2 0.088
tissue migration GO:0090130 119 0.087
regulation of transmembrane transporter activity GO:0022898 74 0.086
protein modification by small protein conjugation GO:0032446 342 0.085
photoreceptor cell differentiation GO:0046530 2 0.084
organelle fission GO:0048285 149 0.084
regulation of dephosphorylation GO:0035303 96 0.084
positive regulation of rho gtpase activity GO:0032321 56 0.084
protein localization to plasma membrane GO:0072659 93 0.084
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.084
negative regulation of protein processing GO:0010955 142 0.081
regulation of rho protein signal transduction GO:0035023 79 0.081
single organism membrane organization GO:0044802 268 0.079
cell growth GO:0016049 160 0.079
metal ion transport GO:0030001 272 0.079
regulation of cell cycle process GO:0010564 266 0.079
segmentation GO:0035282 4 0.077
membrane organization GO:0061024 292 0.077
regulation of establishment of protein localization GO:0070201 242 0.076
regulation of nucleocytoplasmic transport GO:0046822 98 0.076
circulatory system development GO:0072359 262 0.076
histone modification GO:0016570 251 0.076
negative regulation of organelle organization GO:0010639 126 0.075
regulation of peptidase activity GO:0052547 180 0.075
regulation of sodium ion transmembrane transport GO:1902305 23 0.074
embryonic morphogenesis GO:0048598 85 0.073
negative regulation of cell development GO:0010721 48 0.073
guanosine containing compound metabolic process GO:1901068 244 0.073
positive regulation of cell development GO:0010720 92 0.072
glycosyl compound catabolic process GO:1901658 413 0.072
regulation of ras gtpase activity GO:0032318 128 0.072
regulation of sodium ion transmembrane transporter activity GO:2000649 17 0.071
oogenesis GO:0048477 2 0.071
negative regulation of cell migration GO:0030336 102 0.070
mitochondrion organization GO:0007005 156 0.069
regulation of potassium ion transmembrane transport GO:1901379 20 0.069
regulation of cysteine type endopeptidase activity GO:2000116 127 0.066
negative regulation of phosphorus metabolic process GO:0010563 267 0.066
regulation of sodium ion transport GO:0002028 24 0.066
negative regulation of programmed cell death GO:0043069 321 0.065
embryonic epithelial tube formation GO:0001838 4 0.065
response to abiotic stimulus GO:0009628 336 0.064
interleukin 6 production GO:0032635 37 0.063
i kappab kinase nf kappab signaling GO:0007249 166 0.063
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.063
neurological system process GO:0050877 163 0.063
regulation of protein maturation GO:1903317 150 0.063
positive regulation of interleukin 6 production GO:0032755 21 0.062
establishment of mitotic spindle localization GO:0040001 8 0.062
positive regulation of nucleotide catabolic process GO:0030813 185 0.061
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.060
protein processing GO:0016485 226 0.060
intrinsic apoptotic signaling pathway GO:0097193 127 0.060
positive regulation of intracellular protein transport GO:0090316 76 0.060
positive regulation of transport GO:0051050 336 0.060
maintenance of location GO:0051235 112 0.060
protein targeting GO:0006605 187 0.059
regulation of growth GO:0040008 165 0.059
regulation of transmembrane transport GO:0034762 139 0.058
regulation of map kinase activity GO:0043405 108 0.058
regulation of potassium ion transmembrane transporter activity GO:1901016 16 0.058
regulation of gtpase activity GO:0043087 180 0.058
regulation of epithelial cell migration GO:0010632 93 0.057
regulation of cellular component movement GO:0051270 334 0.056
stem cell division GO:0017145 2 0.056
Worm
regulation of cell cycle GO:0051726 393 0.056
regulation of intracellular transport GO:0032386 195 0.056
monovalent inorganic cation transport GO:0015672 128 0.056
establishment of protein localization to organelle GO:0072594 172 0.056
cytokinesis GO:0000910 96 0.055
positive regulation of gtp catabolic process GO:0033126 166 0.055
potassium ion transmembrane transport GO:0071805 60 0.055
regulation of cellular amino acid metabolic process GO:0006521 6 0.054
response to growth factor GO:0070848 205 0.054
regulation of membrane repolarization GO:0060306 16 0.054
protein deubiquitination GO:0016579 79 0.053
neuromuscular junction development GO:0007528 3 0.053
regulation of nucleotide metabolic process GO:0006140 269 0.053
muscle contraction GO:0006936 73 0.053
nucleocytoplasmic transport GO:0006913 176 0.053
negative regulation of phosphorylation GO:0042326 174 0.052
guanosine containing compound catabolic process GO:1901069 239 0.052
establishment of protein localization to membrane GO:0090150 121 0.051
regulation of membrane potential GO:0042391 95 0.051
cellular response to organonitrogen compound GO:0071417 124 0.051
neuroblast proliferation GO:0007405 4 0.051
Worm
covalent chromatin modification GO:0016569 254 0.051
endothelial cell migration GO:0043542 86 0.051
cellular response to growth factor stimulus GO:0071363 197 0.050
negative regulation of apoptotic process GO:0043066 316 0.050
behavior GO:0007610 112 0.049
cellular response to dna damage stimulus GO:0006974 379 0.049
single organismal cell cell adhesion GO:0016337 148 0.049
actin filament organization GO:0007015 128 0.049
positive regulation of cytoplasmic transport GO:1903651 82 0.049
regulation of purine nucleotide metabolic process GO:1900542 264 0.049
protein k63 linked deubiquitination GO:0070536 21 0.048
enzyme linked receptor protein signaling pathway GO:0007167 303 0.048
negative regulation of dephosphorylation GO:0035305 63 0.048
regulation of homeostatic process GO:0032844 121 0.048
response to nitrogen compound GO:1901698 184 0.048
chromatin modification GO:0016568 298 0.048
negative regulation of cell motility GO:2000146 104 0.047
positive regulation of nucleoside metabolic process GO:0045979 186 0.047
carbohydrate metabolic process GO:0005975 207 0.047
adult locomotory behavior GO:0008344 1 0.047
negative regulation of protein modification process GO:0031400 200 0.046
negative regulation of protein phosphorylation GO:0001933 140 0.046
negative regulation of peptidase activity GO:0010466 91 0.046
positive regulation of nervous system development GO:0051962 54 0.046
regulation of protein binding GO:0043393 66 0.045
lipid catabolic process GO:0016042 84 0.044
regulation of protein targeting GO:1903533 91 0.044
maintenance of location in cell GO:0051651 62 0.044
blastoderm segmentation GO:0007350 2 0.044
negative regulation of cell death GO:0060548 345 0.044
regulation of protein catabolic process GO:0042176 155 0.044
central nervous system development GO:0007417 123 0.043
cell cell junction organization GO:0045216 69 0.043
negative regulation of protein transport GO:0051224 75 0.043
posttranscriptional regulation of gene expression GO:0010608 213 0.043
positive regulation of cell growth GO:0030307 48 0.043
cellular response to endogenous stimulus GO:0071495 336 0.042
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.042
tor signaling GO:0031929 39 0.042
atp catabolic process GO:0006200 157 0.042
chemotaxis GO:0006935 157 0.042
regulation of ion transport GO:0043269 189 0.042
neural tube formation GO:0001841 3 0.041
regulation of protein processing GO:0070613 150 0.041
limbic system development GO:0021761 3 0.041
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.040
cell projection morphogenesis GO:0048858 129 0.040
cell junction organization GO:0034330 79 0.040
lipid metabolic process GO:0006629 381 0.040
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.039
spindle localization GO:0051653 12 0.039
positive regulation of neuron differentiation GO:0045666 40 0.039
regulation of cellular response to growth factor stimulus GO:0090287 76 0.039
purine nucleoside monophosphate catabolic process GO:0009128 158 0.039
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.038
response to organonitrogen compound GO:0010243 156 0.038
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.038
negative regulation of cellular amine metabolic process GO:0033239 3 0.038
cellular response to oxygen containing compound GO:1901701 276 0.037
plasma membrane organization GO:0007009 115 0.037
nucleoside phosphate biosynthetic process GO:1901293 109 0.037
modification dependent protein catabolic process GO:0019941 209 0.037
atp metabolic process GO:0046034 176 0.037
regulation of cell shape GO:0008360 48 0.037
nuclear division GO:0000280 128 0.037
nuclear migration GO:0007097 1 0.037
protein localization to organelle GO:0033365 280 0.036
regulation of tumor necrosis factor production GO:0032680 43 0.036
negative regulation of intracellular signal transduction GO:1902532 183 0.035
epithelium migration GO:0090132 119 0.035
morphogenesis of embryonic epithelium GO:0016331 4 0.035
cellular response to cytokine stimulus GO:0071345 181 0.035
negative regulation of cytoskeleton organization GO:0051494 45 0.035
positive regulation of meiotic cell cycle GO:0051446 2 0.035
positive regulation of mitotic cell cycle GO:0045931 60 0.035
membrane repolarization GO:0086009 23 0.035
regulation of interleukin 6 production GO:0032675 37 0.035
regulation of blood vessel endothelial cell migration GO:0043535 30 0.034
positive regulation of synaptic transmission GO:0050806 4 0.034
positive regulation of glial cell proliferation GO:0060252 2 0.034
vasculature development GO:0001944 181 0.034
ubiquitin dependent protein catabolic process GO:0006511 206 0.034
generation of precursor metabolites and energy GO:0006091 68 0.034
axonogenesis GO:0007409 31 0.034
specification of axis polarity GO:0065001 1 0.033
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.033
innate immune response GO:0045087 178 0.033
establishment of planar polarity GO:0001736 3 0.033
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.033
purine nucleoside monophosphate metabolic process GO:0009126 186 0.033
negative regulation of epithelial cell migration GO:0010633 38 0.033
positive regulation of protein targeting to membrane GO:0090314 8 0.033
positive regulation of ion transport GO:0043270 87 0.033
cellular homeostasis GO:0019725 196 0.033
mitochondrial respiratory chain complex assembly GO:0033108 23 0.032
negative regulation of protein kinase activity GO:0006469 98 0.032
regulation of cell growth GO:0001558 135 0.032
neuron projection morphogenesis GO:0048812 50 0.032
cellular protein catabolic process GO:0044257 261 0.032
hindbrain development GO:0030902 3 0.031
negative regulation of protein depolymerization GO:1901880 17 0.031
tumor necrosis factor production GO:0032640 43 0.031
regulation of cell migration GO:0030334 289 0.031
regulation of neuron differentiation GO:0045664 70 0.031
cell migration involved in sprouting angiogenesis GO:0002042 19 0.031
reproduction GO:0000003 63 0.031
Worm
memory GO:0007613 3 0.031
negative regulation of endopeptidase activity GO:0010951 84 0.031
mitotic cell cycle phase transition GO:0044772 162 0.031
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.031
brain development GO:0007420 97 0.031
negative regulation of cellular component movement GO:0051271 106 0.031
positive regulation of cell proliferation GO:0008284 301 0.030
Human
regulation of response to biotic stimulus GO:0002831 55 0.030
positive regulation of proteolysis GO:0045862 142 0.030
monocarboxylic acid metabolic process GO:0032787 185 0.029
eye photoreceptor cell differentiation GO:0001754 2 0.029
regulation of dna metabolic process GO:0051052 153 0.029
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.029
maintenance of protein location in cell GO:0032507 56 0.029
somatic muscle development GO:0007525 1 0.029
release of cytochrome c from mitochondria GO:0001836 35 0.028
tube development GO:0035295 125 0.028
cellular response to abiotic stimulus GO:0071214 117 0.028
regulation of proteasomal protein catabolic process GO:0061136 87 0.028
reproductive process GO:0022414 106 0.028
Worm
regulation of peptidyl serine dephosphorylation GO:1902308 2 0.028
protein homooligomerization GO:0051260 100 0.028
protein ubiquitination GO:0016567 314 0.028
regulation of apoptotic signaling pathway GO:2001233 175 0.028
positive regulation of intracellular transport GO:0032388 104 0.027
negative regulation of transferase activity GO:0051348 124 0.027
single organism nuclear import GO:1902593 104 0.027
reactive oxygen species biosynthetic process GO:1903409 4 0.027
nucleotide biosynthetic process GO:0009165 109 0.027
head development GO:0060322 108 0.027
embryonic placenta development GO:0001892 1 0.027
positive regulation of gliogenesis GO:0014015 4 0.027
neurotransmitter secretion GO:0007269 4 0.027
negative regulation of t cell apoptotic process GO:0070233 4 0.027
striated muscle contraction GO:0006941 52 0.027
response to bacterium GO:0009617 144 0.027
regulation of intracellular protein transport GO:0033157 123 0.027
negative regulation of vasculature development GO:1901343 43 0.027
midbrain development GO:0030901 45 0.027
positive regulation of neurogenesis GO:0050769 49 0.026
primary neural tube formation GO:0014020 3 0.026
locomotory behavior GO:0007626 1 0.026
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.026
negative regulation of nervous system development GO:0051961 28 0.026
immune effector process GO:0002252 159 0.026
intracellular receptor signaling pathway GO:0030522 104 0.026
secretion GO:0046903 254 0.026
positive regulation of neuron projection development GO:0010976 34 0.026
epithelial cell migration GO:0010631 119 0.026
protein modification by small protein removal GO:0070646 92 0.026
collateral sprouting GO:0048668 2 0.026
regulation of tor signaling GO:0032006 30 0.026
chromatin organization GO:0006325 351 0.025
positive regulation of cell cycle GO:0045787 140 0.025
negative regulation of cell size GO:0045792 3 0.025
blood vessel endothelial cell migration GO:0043534 42 0.025
regulation of multi organism process GO:0043900 157 0.025
response to cytokine GO:0034097 232 0.025
positive regulation of growth GO:0045927 58 0.025
nitrogen compound transport GO:0071705 191 0.025
ribonucleotide biosynthetic process GO:0009260 81 0.024
regulation of axonogenesis GO:0050770 16 0.024
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.024
ribonucleoside monophosphate catabolic process GO:0009158 158 0.024
apical junction assembly GO:0043297 19 0.024
negative regulation of neurogenesis GO:0050768 26 0.024
morphogenesis of a polarized epithelium GO:0001738 3 0.024
negative regulation of hydrolase activity GO:0051346 182 0.024
steroid metabolic process GO:0008202 94 0.024
negative regulation of endothelial cell migration GO:0010596 29 0.024
positive regulation of cytokine production GO:0001819 167 0.024
positive regulation of protein catabolic process GO:0045732 75 0.024
regulation of autophagy GO:0010506 52 0.024
negative regulation of proteolysis GO:0045861 132 0.023
positive regulation of organelle organization GO:0010638 195 0.023
cellular protein complex assembly GO:0043623 188 0.023
digestive tract development GO:0048565 75 0.023
microtubule depolymerization GO:0007019 18 0.023
cellular response to hormone stimulus GO:0032870 125 0.023
cardiovascular system development GO:0072358 262 0.023
positive regulation of epithelial cell proliferation GO:0050679 65 0.023
negative regulation of cytokine production GO:0001818 82 0.023
ribonucleoside monophosphate metabolic process GO:0009161 187 0.022
mitochondrion transport along microtubule GO:0047497 3 0.022
regulation of cell division GO:0051302 116 0.022
regulation of mitotic cell cycle GO:0007346 189 0.022
response to oxygen containing compound GO:1901700 369 0.022
positive regulation of cellular component biogenesis GO:0044089 158 0.022
membrane depolarization during action potential GO:0086010 10 0.022
organonitrogen compound biosynthetic process GO:1901566 200 0.022
regulation of anatomical structure size GO:0090066 101 0.022

MARK2 disease predictions

Disease DO term ID Size Probability Func Analog Org
synucleinopathy DOID:0050890 22 0.036
central nervous system disease DOID:331 186 0.036
neurodegenerative disease DOID:1289 102 0.036
nervous system disease DOID:863 431 0.036
parkinson s disease DOID:14330 18 0.031