Homo sapiens

24 known processes

MCM2

minichromosome maintenance complex component 2

(Aliases: CCNL1,MGC10606,BM28,cdc19,KIAA0030,MITOTIN,CDCL1,D3S3194)

MCM2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna dependent dna replication GO:0006261 44 1.000
dna replication initiation GO:0006270 6 1.000
dna replication GO:0006260 116 1.000
double strand break repair via homologous recombination GO:0000724 50 0.994
Yeast
recombinational repair GO:0000725 50 0.994
Yeast
dna geometric change GO:0032392 32 0.992
Yeast Mouse
dna conformation change GO:0071103 113 0.992
Yeast Mouse
protein dna complex assembly GO:0065004 64 0.988
Yeast Mouse
double strand break repair GO:0006302 101 0.981
Yeast
mitotic cell cycle phase transition GO:0044772 162 0.976
cellular response to dna damage stimulus GO:0006974 379 0.970
Yeast
dna repair GO:0006281 198 0.936
Yeast
mitotic cell cycle process GO:1903047 286 0.930
dna unwinding involved in dna replication GO:0006268 2 0.914
Mouse
dna packaging GO:0006323 77 0.899
Mouse
post embryonic development GO:0009791 2 0.895
Worm
dna strand elongation involved in dna replication GO:0006271 3 0.890
Yeast
chromosome condensation GO:0030261 15 0.883
negative regulation of cell cycle process GO:0010948 121 0.848
g2 dna damage checkpoint GO:0031572 26 0.833
protein dna complex subunit organization GO:0071824 80 0.814
Yeast Mouse
regulation of dna replication GO:0006275 68 0.813
cell cycle checkpoint GO:0000075 117 0.811
regulation of dna metabolic process GO:0051052 153 0.790
Yeast
dna duplex unwinding GO:0032508 30 0.733
Yeast Mouse
meiosis i GO:0007127 4 0.721
negative regulation of cell cycle phase transition GO:1901988 89 0.681
dna recombination GO:0006310 77 0.662
Yeast
nuclear dna replication GO:0033260 6 0.645
Yeast
cell cycle phase transition GO:0044770 173 0.640
negative regulation of mitotic cell cycle GO:0045930 102 0.572
meiotic chromosome segregation GO:0045132 4 0.561
regulation of mitotic cell cycle GO:0007346 189 0.550
organelle fission GO:0048285 149 0.516
cellular macromolecular complex assembly GO:0034622 324 0.503
Yeast Mouse
mitotic dna damage checkpoint GO:0044773 28 0.488
gene silencing GO:0016458 49 0.457
cell cycle dna replication GO:0044786 11 0.451
Yeast
regulation of mitotic cell cycle phase transition GO:1901990 118 0.430
regulation of cell cycle GO:0051726 393 0.425
negative regulation of cell cycle GO:0045786 193 0.383
dna strand elongation GO:0022616 5 0.359
Yeast
mitotic cell cycle GO:0000278 326 0.357
regulation of cell cycle process GO:0010564 266 0.344
regulation of dna dependent dna replication initiation GO:0030174 3 0.335
nuclear division GO:0000280 128 0.332
mitotic nuclear division GO:0007067 119 0.329
growth GO:0040007 202 0.312
female gamete generation GO:0007292 2 0.308
g1 s transition of mitotic cell cycle GO:0000082 78 0.305
mitotic cell cycle checkpoint GO:0007093 68 0.289
regulation of cell cycle phase transition GO:1901987 126 0.274
positive regulation of developmental process GO:0051094 314 0.270
chromatin silencing GO:0006342 12 0.262
regulation of gene silencing GO:0060968 24 0.252
cell cycle g2 m phase transition GO:0044839 43 0.250
organ morphogenesis GO:0009887 147 0.231
dna integrity checkpoint GO:0031570 71 0.211
meiotic chromosome separation GO:0051307 3 0.210
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.183
dna damage checkpoint GO:0000077 68 0.179
embryo development GO:0009790 123 0.173
Worm
reciprocal meiotic recombination GO:0007131 4 0.169
g2 m transition of mitotic cell cycle GO:0000086 41 0.159
response to abiotic stimulus GO:0009628 336 0.157
sister chromatid segregation GO:0000819 54 0.139
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.137
reproductive process GO:0022414 106 0.131
Worm
purine ribonucleoside metabolic process GO:0046128 437 0.125
Yeast
mitotic dna integrity checkpoint GO:0044774 30 0.117
response to fungus GO:0009620 4 0.116
single organism reproductive process GO:0044702 98 0.108
Worm
negative regulation of cell death GO:0060548 345 0.108
regulation of meiotic cell cycle GO:0051445 4 0.105
purine containing compound biosynthetic process GO:0072522 88 0.100
microtubule based process GO:0007017 210 0.095
developmental process involved in reproduction GO:0003006 66 0.090
Worm
cell cell signaling involved in cell fate commitment GO:0045168 5 0.089
negative regulation of gene expression epigenetic GO:0045814 19 0.089
cell aging GO:0007569 52 0.088
resolution of meiotic recombination intermediates GO:0000712 3 0.086
reproduction GO:0000003 63 0.086
Worm
negative regulation of programmed cell death GO:0043069 321 0.084
regulation of transcription by chromatin organization GO:0034401 1 0.081
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.081
mitotic g2 dna damage checkpoint GO:0007095 7 0.080
neurogenesis GO:0022008 169 0.080
dna biosynthetic process GO:0071897 40 0.078
cell development GO:0048468 328 0.076
chromatin organization GO:0006325 351 0.075
Mouse
mitotic spindle organization GO:0007052 27 0.071
positive regulation of cellular component organization GO:0051130 376 0.069
embryo development ending in birth or egg hatching GO:0009792 34 0.066
Worm
reciprocal dna recombination GO:0035825 4 0.065
positive regulation of cell proliferation GO:0008284 301 0.065
response to inorganic substance GO:0010035 127 0.064
dna endoreduplication GO:0042023 5 0.061
microtubule cytoskeleton organization GO:0000226 176 0.058
response to metal ion GO:0010038 84 0.057
oogenesis GO:0048477 2 0.057
reproductive system development GO:0061458 56 0.056
Worm
regulation of gene expression epigenetic GO:0040029 73 0.056
positive regulation of cell cycle g2 m phase transition GO:1902751 8 0.055
vesicle mediated transport GO:0016192 371 0.053
membrane organization GO:0061024 292 0.051
protein alkylation GO:0008213 74 0.050
cell cycle g1 s phase transition GO:0044843 80 0.050
regulation of response to dna damage stimulus GO:2001020 94 0.048
positive regulation of cell cycle process GO:0090068 106 0.047
lagging strand elongation GO:0006273 3 0.046
neuron projection development GO:0031175 106 0.046
nervous system development GO:0007399 293 0.046
protein localization to nucleus GO:0034504 136 0.045
positive regulation of growth GO:0045927 58 0.043
methylation GO:0032259 106 0.042
response to other organism GO:0051707 261 0.042
mitotic g2 m transition checkpoint GO:0044818 9 0.041
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.040
oocyte differentiation GO:0009994 2 0.040
cell cell signaling GO:0007267 155 0.040
regulation of cellular response to stress GO:0080135 244 0.039
regulation of kinase activity GO:0043549 314 0.039
cell adhesion GO:0007155 325 0.039
dephosphorylation GO:0016311 209 0.039
generation of neurons GO:0048699 152 0.038
response to cadmium ion GO:0046686 10 0.037
regulation of chromatin silencing GO:0031935 8 0.037
response to xenobiotic stimulus GO:0009410 30 0.035
cell morphogenesis GO:0000902 296 0.035
positive regulation of dna metabolic process GO:0051054 73 0.034
ras protein signal transduction GO:0007265 73 0.034
oocyte development GO:0048599 1 0.033
chromosome segregation GO:0007059 114 0.033
positive regulation of dna replication GO:0045740 35 0.032
negative regulation of apoptotic process GO:0043066 316 0.032
organelle assembly GO:0070925 176 0.031
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.031
purine nucleobase metabolic process GO:0006144 5 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.031
Yeast
regulation of microtubule cytoskeleton organization GO:0070507 61 0.030
regulation of microtubule based process GO:0032886 74 0.030
cellular component morphogenesis GO:0032989 314 0.029
positive regulation of cell cycle GO:0045787 140 0.029
segmentation GO:0035282 4 0.028
response to extracellular stimulus GO:0009991 85 0.028
regulation of growth GO:0040008 165 0.028
regulation of meiosis GO:0040020 3 0.027
neuron differentiation GO:0030182 138 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.027
Yeast
camera type eye development GO:0043010 25 0.027
regulation of binding GO:0051098 111 0.027
pteridine containing compound metabolic process GO:0042558 7 0.027
cell projection organization GO:0030030 252 0.027
response to radiation GO:0009314 151 0.026
cellular macromolecule catabolic process GO:0044265 380 0.026
eye development GO:0001654 42 0.026
positive regulation of meiosis i GO:0060903 1 0.026
response to biotic stimulus GO:0009607 276 0.026
regulation of dna repair GO:0006282 47 0.025
regulation of developmental growth GO:0048638 30 0.025
reproductive structure development GO:0048608 55 0.025
Worm
regulation of ras protein signal transduction GO:0046578 155 0.025
enzyme linked receptor protein signaling pathway GO:0007167 303 0.025
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.025
mitotic sister chromatid segregation GO:0000070 53 0.025
negative regulation of meiotic cell cycle GO:0051447 2 0.024
determination of adult lifespan GO:0008340 2 0.024
Worm
organophosphate biosynthetic process GO:0090407 163 0.023
nucleotide biosynthetic process GO:0009165 109 0.023
alpha amino acid metabolic process GO:1901605 72 0.022
regulation of transferase activity GO:0051338 355 0.022
cell division GO:0051301 168 0.022
regulation of nucleotide catabolic process GO:0030811 205 0.021
Yeast
regulation of cell cycle g1 s phase transition GO:1902806 42 0.021
regulation of nuclear division GO:0051783 65 0.021
peptidyl serine phosphorylation GO:0018105 101 0.021
organonitrogen compound biosynthetic process GO:1901566 200 0.021
organophosphate catabolic process GO:0046434 430 0.021
Yeast
jak stat cascade GO:0007259 46 0.021
meiotic cell cycle GO:0051321 13 0.020
response to nutrient levels GO:0031667 81 0.020
rna processing GO:0006396 255 0.020
cellular amino acid metabolic process GO:0006520 116 0.020
regulation of cell adhesion GO:0030155 166 0.019
response to nitrogen compound GO:1901698 184 0.019
meiotic nuclear division GO:0007126 10 0.018
response to external biotic stimulus GO:0043207 261 0.018
hemopoiesis GO:0030097 180 0.018
protein localization to organelle GO:0033365 280 0.018
macromolecule methylation GO:0043414 97 0.018
sex differentiation GO:0007548 45 0.017
Worm
response to organic cyclic compound GO:0014070 204 0.017
cellular component assembly involved in morphogenesis GO:0010927 73 0.017
multi organism reproductive process GO:0044703 54 0.017
engulfment of apoptotic cell GO:0043652 2 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.016
Yeast
positive regulation of multicellular organism growth GO:0040018 6 0.016
regulation of dna dependent dna replication GO:0090329 19 0.016
developmental growth GO:0048589 48 0.016
regulation of cellular ketone metabolic process GO:0010565 50 0.016
multicellular organismal aging GO:0010259 3 0.016
Worm
positive regulation of mitotic cell cycle GO:0045931 60 0.016
intracellular protein transport GO:0006886 270 0.016
cell part morphogenesis GO:0032990 137 0.015
sensory organ development GO:0007423 52 0.015
purine containing compound catabolic process GO:0072523 411 0.015
Yeast
response to oxygen containing compound GO:1901700 369 0.015
regulation of transcription by glucose GO:0046015 4 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
Yeast
chromatin remodeling GO:0006338 55 0.015
biological adhesion GO:0022610 331 0.015
negative regulation of dephosphorylation GO:0035305 63 0.015
protein methylation GO:0006479 74 0.015
tube development GO:0035295 125 0.014
regulation of transcription from rna polymerase ii promoter by glucose GO:0000430 2 0.014
exit from mitosis GO:0010458 10 0.014
protein complex disassembly GO:0043241 52 0.014
regulation of protein kinase activity GO:0045859 289 0.014
chemical homeostasis GO:0048878 306 0.014
spindle organization GO:0007051 53 0.014
response to hypoxia GO:0001666 96 0.014
response to ionizing radiation GO:0010212 65 0.014
nucleoside catabolic process GO:0009164 408 0.014
Yeast
actin filament based process GO:0030029 224 0.014
negative regulation of cytoskeleton organization GO:0051494 45 0.014
cellular component disassembly GO:0022411 92 0.013
protein processing GO:0016485 226 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
endocytosis GO:0006897 159 0.013
ribonucleoside triphosphate metabolic process GO:0009199 412 0.013
Yeast
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.013
response to organophosphorus GO:0046683 41 0.013
development of primary sexual characteristics GO:0045137 35 0.013
Worm
myosin filament organization GO:0031033 2 0.013
regulation of chromosome organization GO:0033044 103 0.012
chromatin modification GO:0016568 298 0.012
oocyte maturation GO:0001556 1 0.012
chordate embryonic development GO:0043009 34 0.012
gonad development GO:0008406 34 0.012
Worm
response to cytokine GO:0034097 232 0.011
Mouse
eye morphogenesis GO:0048592 16 0.011
nuclear transport GO:0051169 179 0.011
cellular response to hypoxia GO:0071456 51 0.011
negative regulation of organelle organization GO:0010639 126 0.011
apoptotic signaling pathway GO:0097190 268 0.011
atp metabolic process GO:0046034 176 0.011
Yeast
dna synthesis involved in dna repair GO:0000731 6 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
Yeast
cofactor metabolic process GO:0051186 87 0.011
regulation of notch signaling pathway GO:0008593 18 0.010
circulatory system development GO:0072359 262 0.010
cardiovascular system development GO:0072358 262 0.010
response to light stimulus GO:0009416 87 0.010
carbohydrate derivative biosynthetic process GO:1901137 207 0.010
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.010
response to heat GO:0009408 21 0.010

MCM2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.047
aicardi goutieres syndrome DOID:0050629 7 0.028
inherited metabolic disorder DOID:655 242 0.022
carbohydrate metabolic disorder DOID:2978 55 0.016