Homo sapiens

96 known processes

MCM7

minichromosome maintenance complex component 7

(Aliases: PNAS146,MCM2,P1.1-MCM3,CDC47,P1CDC47,P85MCM)

MCM7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna replication GO:0006260 116 1.000
Yeast Mouse
dna dependent dna replication GO:0006261 44 1.000
Yeast Mouse
dna replication initiation GO:0006270 6 0.999
Yeast
protein dna complex subunit organization GO:0071824 80 0.999
Yeast
covalent chromatin modification GO:0016569 254 0.981
regulation of cell cycle GO:0051726 393 0.978
Fly
negative regulation of mitotic cell cycle GO:0045930 102 0.977
Fly
protein dna complex assembly GO:0065004 64 0.971
Yeast
negative regulation of cell cycle GO:0045786 193 0.964
Fly
female gamete generation GO:0007292 2 0.950
dna conformation change GO:0071103 113 0.948
dna recombination GO:0006310 77 0.944
Yeast
dna damage checkpoint GO:0000077 68 0.930
Fly
dna strand elongation GO:0022616 5 0.930
Yeast
dna geometric change GO:0032392 32 0.926
chromatin organization GO:0006325 351 0.894
cellular response to dna damage stimulus GO:0006974 379 0.879
post embryonic development GO:0009791 2 0.876
single organism reproductive process GO:0044702 98 0.857
Worm
dna integrity checkpoint GO:0031570 71 0.839
Fly
chromatin modification GO:0016568 298 0.831
double strand break repair GO:0006302 101 0.797
Yeast
dna strand elongation involved in dna replication GO:0006271 3 0.784
Yeast
recombinational repair GO:0000725 50 0.764
Yeast
chromatin silencing GO:0006342 12 0.756
Yeast
mitotic dna damage checkpoint GO:0044773 28 0.736
Fly
mitotic cell cycle process GO:1903047 286 0.734
Fly
negative regulation of cell cycle process GO:0010948 121 0.734
Fly
mitotic cell cycle GO:0000278 326 0.714
Fly
regulation of meiotic cell cycle GO:0051445 4 0.699
organelle fission GO:0048285 149 0.688
mitotic cell cycle phase transition GO:0044772 162 0.674
Fly
dna packaging GO:0006323 77 0.670
mitotic dna integrity checkpoint GO:0044774 30 0.657
Fly
negative regulation of cell cycle phase transition GO:1901988 89 0.644
Fly
nervous system development GO:0007399 293 0.625
development of primary sexual characteristics GO:0045137 35 0.615
Worm
organ morphogenesis GO:0009887 147 0.609
regulation of cell cycle process GO:0010564 266 0.607
Fly
nuclear dna replication GO:0033260 6 0.605
Yeast
atp catabolic process GO:0006200 157 0.589
sex differentiation GO:0007548 45 0.585
Worm
regulation of mitotic cell cycle GO:0007346 189 0.567
Fly
cellular macromolecular complex assembly GO:0034622 324 0.542
Yeast Worm
cell development GO:0048468 328 0.541
dna duplex unwinding GO:0032508 30 0.527
oogenesis GO:0048477 2 0.521
reproductive process GO:0022414 106 0.520
Worm
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.494
cellular component morphogenesis GO:0032989 314 0.481
g2 dna damage checkpoint GO:0031572 26 0.480
Fly
positive regulation of cell cycle process GO:0090068 106 0.469
mitotic cell cycle checkpoint GO:0007093 68 0.469
Fly
regulation of transcription by chromatin organization GO:0034401 1 0.429
reproductive system development GO:0061458 56 0.426
Worm
meiosis i GO:0007127 4 0.423
dna repair GO:0006281 198 0.397
Yeast
sensory organ development GO:0007423 52 0.388
methylation GO:0032259 106 0.387
multicellular organismal aging GO:0010259 3 0.382
embryo development GO:0009790 123 0.360
Worm
mitotic nuclear division GO:0007067 119 0.342
regulation of cellular ketone metabolic process GO:0010565 50 0.337
developmental process involved in reproduction GO:0003006 66 0.314
Worm
regulation of cellular amine metabolic process GO:0033238 11 0.300
eye development GO:0001654 42 0.298
determination of adult lifespan GO:0008340 2 0.295
cell projection morphogenesis GO:0048858 129 0.287
regulation of dna dependent dna replication GO:0090329 19 0.287
positive regulation of cellular catabolic process GO:0031331 284 0.279
nuclear division GO:0000280 128 0.277
regulation of dna dependent dna replication initiation GO:0030174 3 0.275
purine nucleoside triphosphate metabolic process GO:0009144 412 0.275
nucleosome organization GO:0034728 66 0.274
cell morphogenesis GO:0000902 296 0.271
ribonucleoside triphosphate metabolic process GO:0009199 412 0.269
embryo development ending in birth or egg hatching GO:0009792 34 0.258
Worm
negative regulation of gene expression epigenetic GO:0045814 19 0.251
Yeast
chromosome segregation GO:0007059 114 0.249
neurogenesis GO:0022008 169 0.248
protein alkylation GO:0008213 74 0.242
meiotic chromosome separation GO:0051307 3 0.226
regulation of establishment of protein localization GO:0070201 242 0.224
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.222
double strand break repair via homologous recombination GO:0000724 50 0.213
Yeast
negative regulation of chromatin silencing GO:0031936 4 0.201
cell cycle g1 s phase transition GO:0044843 80 0.199
cell cell signaling GO:0007267 155 0.196
cell cycle checkpoint GO:0000075 117 0.196
Fly
reproductive structure development GO:0048608 55 0.193
Worm
regulation of dna replication GO:0006275 68 0.191
reproduction GO:0000003 63 0.189
Worm
microtubule organizing center organization GO:0031023 62 0.188
gonad development GO:0008406 34 0.181
Worm
atp metabolic process GO:0046034 176 0.179
g1 s transition of mitotic cell cycle GO:0000082 78 0.176
regulation of nucleotide metabolic process GO:0006140 269 0.169
regulation of gene expression epigenetic GO:0040029 73 0.166
Yeast
cell cycle dna replication GO:0044786 11 0.164
Yeast
cell cell signaling involved in cell fate commitment GO:0045168 5 0.163
positive regulation of apoptotic process GO:0043065 246 0.159
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.156
meiotic chromosome segregation GO:0045132 4 0.147
cell cycle g2 m phase transition GO:0044839 43 0.146
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.140
Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.140
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.139
developmental growth GO:0048589 48 0.138
vesicle mediated transport GO:0016192 371 0.137
tube development GO:0035295 125 0.125
cellular ketone metabolic process GO:0042180 80 0.123
purine ribonucleotide catabolic process GO:0009154 404 0.119
macromolecule methylation GO:0043414 97 0.116
nucleoside triphosphate metabolic process GO:0009141 422 0.113
eye morphogenesis GO:0048592 16 0.105
lagging strand elongation GO:0006273 3 0.103
resolution of meiotic recombination intermediates GO:0000712 3 0.102
regulation of cell cycle g1 s phase transition GO:1902806 42 0.102
regulation of cell cycle phase transition GO:1901987 126 0.101
Fly
chromosome separation GO:0051304 23 0.101
purine ribonucleoside metabolic process GO:0046128 437 0.100
response to other organism GO:0051707 261 0.099
cell type specific apoptotic process GO:0097285 125 0.098
meiotic nuclear division GO:0007126 10 0.097
segmentation GO:0035282 4 0.096
microtubule based process GO:0007017 210 0.093
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.092
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.090
response to external biotic stimulus GO:0043207 261 0.083
positive regulation of cell proliferation GO:0008284 301 0.083
ribonucleoside catabolic process GO:0042454 406 0.081
purine nucleoside triphosphate catabolic process GO:0009146 392 0.079
histone lysine methylation GO:0034968 50 0.078
regulation of dna metabolic process GO:0051052 153 0.076
response to abiotic stimulus GO:0009628 336 0.073
negative regulation of programmed cell death GO:0043069 321 0.070
negative regulation of cell death GO:0060548 345 0.070
positive regulation of hydrolase activity GO:0051345 331 0.069
multicellular organismal reproductive process GO:0048609 40 0.068
multi organism reproductive process GO:0044703 54 0.066
genitalia development GO:0048806 10 0.063
Worm
growth GO:0040007 202 0.063
response to metal ion GO:0010038 84 0.063
lymphocyte activation GO:0046649 133 0.062
neuron projection morphogenesis GO:0048812 50 0.061
chromosome condensation GO:0030261 15 0.061
peptidyl tyrosine phosphorylation GO:0018108 170 0.061
reciprocal meiotic recombination GO:0007131 4 0.061
chromatin assembly GO:0031497 61 0.061
spindle organization GO:0007051 53 0.056
circulatory system development GO:0072359 262 0.056
cellular amine metabolic process GO:0044106 41 0.055
positive regulation of developmental process GO:0051094 314 0.054
histone methylation GO:0016571 60 0.054
cell cycle phase transition GO:0044770 173 0.053
Fly
mitotic g2 m transition checkpoint GO:0044818 9 0.053
Fly
positive regulation of cell death GO:0010942 263 0.053
purine ribonucleoside catabolic process GO:0046130 398 0.051
regulation of nucleotide catabolic process GO:0030811 205 0.051
sister chromatid cohesion GO:0007062 24 0.051
regulation of gene silencing GO:0060968 24 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
cell projection organization GO:0030030 252 0.049
nucleoside triphosphate catabolic process GO:0009143 394 0.048
nucleoside monophosphate metabolic process GO:0009123 191 0.046
centrosome organization GO:0051297 58 0.046
negative regulation of cellular component organization GO:0051129 235 0.045
pattern specification process GO:0007389 43 0.043
regulation of mitotic cell cycle phase transition GO:1901990 118 0.043
Fly
anatomical structure formation involved in morphogenesis GO:0048646 284 0.041
nucleoside phosphate catabolic process GO:1901292 412 0.040
response to cytokine GO:0034097 232 0.039
cell fate commitment GO:0045165 27 0.039
multicellular organism reproduction GO:0032504 42 0.039
apoptotic signaling pathway GO:0097190 268 0.038
sexual reproduction GO:0019953 37 0.038
cellular component assembly involved in morphogenesis GO:0010927 73 0.038
response to biotic stimulus GO:0009607 276 0.037
meiotic cell cycle GO:0051321 13 0.037
regulation of cellular amino acid metabolic process GO:0006521 6 0.036
epithelium development GO:0060429 227 0.035
cardiovascular system development GO:0072358 262 0.034
cell division GO:0051301 168 0.034
ribonucleoside monophosphate catabolic process GO:0009158 158 0.032
histone modification GO:0016570 251 0.032
generation of neurons GO:0048699 152 0.031
positive regulation of cell cycle GO:0045787 140 0.031
immune system development GO:0002520 195 0.030
purine containing compound catabolic process GO:0072523 411 0.030
endocytosis GO:0006897 159 0.029
protein complex localization GO:0031503 31 0.029
osteoblast differentiation GO:0001649 92 0.029
gene looping GO:0090202 1 0.028
regulation of purine nucleotide metabolic process GO:1900542 264 0.028
regulation of cellular response to stress GO:0080135 244 0.028
intrinsic apoptotic signaling pathway GO:0097193 127 0.028
regionalization GO:0003002 29 0.028
nucleus localization GO:0051647 1 0.027
nucleoside catabolic process GO:0009164 408 0.027
response to hypoxia GO:0001666 96 0.026
response to temperature stimulus GO:0009266 22 0.026
positive regulation of cellular component organization GO:0051130 376 0.025
neuron differentiation GO:0030182 138 0.025
chromatin remodeling GO:0006338 55 0.025
positive regulation of proteolysis GO:0045862 142 0.025
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.025
mitotic g2 dna damage checkpoint GO:0007095 7 0.024
Fly
peptidyl serine phosphorylation GO:0018105 101 0.024
cellular amino acid metabolic process GO:0006520 116 0.023
regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:1902165 7 0.023
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.023
regulation of proteolysis GO:0030162 293 0.023
regulation of meiosis GO:0040020 3 0.023
regulation of spindle checkpoint GO:0090231 12 0.023
regulation of gtp catabolic process GO:0033124 180 0.022
cell part morphogenesis GO:0032990 137 0.022
regulation of gtpase activity GO:0043087 180 0.022
hemopoiesis GO:0030097 180 0.022
neuron development GO:0048666 113 0.022
protein localization to nucleus GO:0034504 136 0.022
response to xenobiotic stimulus GO:0009410 30 0.022
gamete generation GO:0007276 25 0.021
amine metabolic process GO:0009308 44 0.021
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.021
positive regulation of cellular amine metabolic process GO:0033240 7 0.021
nuclear transport GO:0051169 179 0.021
regulation of mitotic cell cycle spindle assembly checkpoint GO:0090266 8 0.021
b cell activation GO:0042113 33 0.020
camera type eye development GO:0043010 25 0.020
single organism nuclear import GO:1902593 104 0.020
regulation of mitotic recombination GO:0000019 1 0.020
carbohydrate derivative biosynthetic process GO:1901137 207 0.020
regulation of protein localization GO:0032880 296 0.020
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.020
microtubule cytoskeleton organization GO:0000226 176 0.019
transcriptional activation by promoter enhancer looping GO:0071733 1 0.019
mature ribosome assembly GO:0042256 5 0.019
dna biosynthetic process GO:0071897 40 0.019
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.019
dna modification GO:0006304 27 0.019
dna endoreduplication GO:0042023 5 0.018
neuron projection development GO:0031175 106 0.018
embryonic morphogenesis GO:0048598 85 0.018
heart development GO:0007507 95 0.018
purine nucleoside catabolic process GO:0006152 398 0.017
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.017
ribonucleotide catabolic process GO:0009261 405 0.017
response to inorganic substance GO:0010035 127 0.016
dna unwinding involved in dna replication GO:0006268 2 0.016
Yeast Mouse
nucleotide catabolic process GO:0009166 408 0.016
cell activation GO:0001775 213 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
response to decreased oxygen levels GO:0036293 96 0.016
response to fungus GO:0009620 4 0.015
positive regulation of mitotic cell cycle GO:0045931 60 0.015
single organism cellular localization GO:1902580 332 0.015
regulation of growth GO:0040008 165 0.015
taxis GO:0042330 157 0.015
regulation of protein catabolic process GO:0042176 155 0.015
protein localization to organelle GO:0033365 280 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
nuclear migration GO:0007097 1 0.015
regulation of cell division GO:0051302 116 0.014
negative regulation of organelle organization GO:0010639 126 0.014
protein targeting GO:0006605 187 0.014
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.014
positive regulation of mitotic cell cycle spindle assembly checkpoint GO:0090267 6 0.014
regulation of cellular respiration GO:0043457 4 0.014
germ cell development GO:0007281 8 0.013
regulation of cell activation GO:0050865 125 0.013
peptidyl serine modification GO:0018209 106 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.012
purine nucleoside monophosphate catabolic process GO:0009128 158 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
transcription factor import into nucleus GO:0042991 40 0.012
regulation of histone acetylation GO:0035065 19 0.012
digestive system development GO:0055123 75 0.012
regulation of centriole replication GO:0046599 7 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
regulation of mitotic spindle checkpoint GO:1903504 8 0.011
leukocyte activation GO:0045321 164 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
regulation of protein targeting GO:1903533 91 0.011
purine nucleotide catabolic process GO:0006195 405 0.011
regulation of nuclear division GO:0051783 65 0.011
nucleosome assembly GO:0006334 50 0.011
nucleus organization GO:0006997 28 0.011
cell aging GO:0007569 52 0.011
gene silencing GO:0016458 49 0.011
Yeast
rna 3 end processing GO:0031123 35 0.011
regulation of mrna metabolic process GO:1903311 53 0.011
er overload response GO:0006983 5 0.010
phagocytosis GO:0006909 42 0.010
cell morphogenesis involved in differentiation GO:0000904 144 0.010

MCM7 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.069
cancer DOID:162 167 0.035
organ system cancer DOID:0050686 164 0.022
musculoskeletal system disease DOID:17 223 0.012