Homo sapiens

0 known processes

MDH1

malate dehydrogenase 1, NAD (soluble)

(Aliases: MOR2,MDH-s,MDHA,MGC:1375)

MDH1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 396 0.785
Fly
atp metabolic process GO:0046034 176 0.512
reactive oxygen species metabolic process GO:0072593 75 0.496
ribonucleoside triphosphate metabolic process GO:0009199 412 0.387
nucleoside monophosphate metabolic process GO:0009123 191 0.359
determination of adult lifespan GO:0008340 2 0.356
purine ribonucleoside metabolic process GO:0046128 437 0.352
lipid metabolic process GO:0006629 381 0.334
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.308
cellular lipid metabolic process GO:0044255 303 0.295
purine nucleoside triphosphate metabolic process GO:0009144 412 0.288
nucleoside triphosphate metabolic process GO:0009141 422 0.247
purine ribonucleoside catabolic process GO:0046130 398 0.232
nucleoside catabolic process GO:0009164 408 0.218
ribonucleoside monophosphate metabolic process GO:0009161 187 0.215
cation transport GO:0006812 331 0.204
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.203
protein processing GO:0016485 226 0.191
nervous system development GO:0007399 293 0.190
energy derivation by oxidation of organic compounds GO:0015980 43 0.188
multicellular organismal aging GO:0010259 3 0.187
midbrain development GO:0030901 45 0.185
monocarboxylic acid metabolic process GO:0032787 185 0.185
brain development GO:0007420 97 0.174
lipid oxidation GO:0034440 33 0.158
substantia nigra development GO:0021762 45 0.157
inorganic cation transmembrane transport GO:0098662 194 0.156
inorganic ion transmembrane transport GO:0098660 231 0.150
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.134
purine containing compound catabolic process GO:0072523 411 0.124
response to oxidative stress GO:0006979 121 0.118
purine containing compound biosynthetic process GO:0072522 88 0.118
nucleoside triphosphate catabolic process GO:0009143 394 0.117
glycosyl compound catabolic process GO:1901658 413 0.117
regulation of membrane potential GO:0042391 95 0.115
nucleoside phosphate catabolic process GO:1901292 412 0.114
purine ribonucleoside biosynthetic process GO:0046129 23 0.113
central nervous system development GO:0007417 123 0.107
response to oxygen containing compound GO:1901700 369 0.106
post embryonic development GO:0009791 2 0.096
ribonucleoside triphosphate catabolic process GO:0009203 391 0.096
regulation of apoptotic signaling pathway GO:2001233 175 0.093
purine nucleoside triphosphate catabolic process GO:0009146 392 0.092
purine nucleoside monophosphate metabolic process GO:0009126 186 0.092
purine nucleoside monophosphate catabolic process GO:0009128 158 0.086
alcohol metabolic process GO:0006066 114 0.082
lipid catabolic process GO:0016042 84 0.082
carbohydrate derivative biosynthetic process GO:1901137 207 0.082
head development GO:0060322 108 0.082
ribonucleotide catabolic process GO:0009261 405 0.079
atp biosynthetic process GO:0006754 11 0.075
neural nucleus development GO:0048857 47 0.074
purine ribonucleotide catabolic process GO:0009154 404 0.074
ras protein signal transduction GO:0007265 73 0.072
organic hydroxy compound metabolic process GO:1901615 147 0.072
cellular amine metabolic process GO:0044106 41 0.070
generation of precursor metabolites and energy GO:0006091 68 0.067
response to xenobiotic stimulus GO:0009410 30 0.065
glycosyl compound biosynthetic process GO:1901659 27 0.063
oogenesis GO:0048477 2 0.063
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.060
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.059
monovalent inorganic cation transport GO:0015672 128 0.059
monocarboxylic acid catabolic process GO:0072329 37 0.056
system process GO:0003008 349 0.056
hydrogen peroxide metabolic process GO:0042743 20 0.056
energy coupled proton transport down electrochemical gradient GO:0015985 2 0.055
organophosphate catabolic process GO:0046434 430 0.054
apoptotic mitochondrial changes GO:0008637 57 0.053
regeneration GO:0031099 4 0.053
atp synthesis coupled electron transport GO:0042773 4 0.053
lipid biosynthetic process GO:0008610 177 0.048
single organism carbohydrate metabolic process GO:0044723 193 0.048
spermatid differentiation GO:0048515 4 0.045
ribonucleoside catabolic process GO:0042454 406 0.045
nucleoside monophosphate catabolic process GO:0009125 159 0.043
tricarboxylic acid cycle GO:0006099 4 0.042
maintenance of location GO:0051235 112 0.042
mating GO:0007618 1 0.040
cellular ketone metabolic process GO:0042180 80 0.038
response to decreased oxygen levels GO:0036293 96 0.037
spermatid development GO:0007286 4 0.037
response to hormone GO:0009725 175 0.037
epithelium development GO:0060429 227 0.037
cation transmembrane transport GO:0098655 238 0.037
nucleotide catabolic process GO:0009166 408 0.036
purine nucleotide catabolic process GO:0006195 405 0.035
female gamete generation GO:0007292 2 0.035
succinate metabolic process GO:0006105 1 0.034
response to activity GO:0014823 0 0.034
mitochondrial electron transport nadh to ubiquinone GO:0006120 2 0.034
organonitrogen compound biosynthetic process GO:1901566 200 0.034
small molecule biosynthetic process GO:0044283 157 0.034
ribonucleoside triphosphate biosynthetic process GO:0009201 12 0.034
response to reactive oxygen species GO:0000302 61 0.033
purine nucleotide biosynthetic process GO:0006164 84 0.033
sulfur compound biosynthetic process GO:0044272 38 0.032
positive regulation of hydrolase activity GO:0051345 331 0.031
ossification GO:0001503 121 0.031
regulation of cellular ketone metabolic process GO:0010565 50 0.031
fatty acid metabolic process GO:0006631 115 0.030
purine ribonucleotide biosynthetic process GO:0009152 79 0.030
ribonucleoside biosynthetic process GO:0042455 25 0.029
cellular metal ion homeostasis GO:0006875 146 0.029
regulation of ras protein signal transduction GO:0046578 155 0.029
positive regulation of apoptotic process GO:0043065 246 0.029
cellular macromolecular complex assembly GO:0034622 324 0.028
chemical homeostasis GO:0048878 306 0.028
ribonucleoside monophosphate catabolic process GO:0009158 158 0.028
reactive oxygen species biosynthetic process GO:1903409 4 0.027
regulation of mitochondrial membrane potential GO:0051881 23 0.027
osteoblast differentiation GO:0001649 92 0.026
immune system development GO:0002520 195 0.026
multicellular organismal response to stress GO:0033555 1 0.026
aspartate metabolic process GO:0006531 4 0.025
anatomical structure homeostasis GO:0060249 100 0.025
response to inorganic substance GO:0010035 127 0.025
organic acid biosynthetic process GO:0016053 97 0.025
regulation of endopeptidase activity GO:0052548 170 0.025
skin development GO:0043588 76 0.024
atp catabolic process GO:0006200 157 0.024
small molecule catabolic process GO:0044282 92 0.024
ribonucleotide biosynthetic process GO:0009260 81 0.024
regulation of cellular amine metabolic process GO:0033238 11 0.024
anatomical structure formation involved in morphogenesis GO:0048646 284 0.024
regulation of transferase activity GO:0051338 355 0.024
regulation of small gtpase mediated signal transduction GO:0051056 156 0.023
nucleotide biosynthetic process GO:0009165 109 0.023
hydrogen ion transmembrane transport GO:1902600 15 0.023
cellular respiration GO:0045333 21 0.023
cellular response to oxygen containing compound GO:1901701 276 0.023
lipid localization GO:0010876 106 0.022
cell cell signaling GO:0007267 155 0.022
Fly
aging GO:0007568 66 0.022
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.021
ion homeostasis GO:0050801 230 0.021
cellular homeostasis GO:0019725 196 0.021
reproduction GO:0000003 63 0.021
regulation of endothelial cell proliferation GO:0001936 56 0.021
epithelial cell differentiation GO:0030855 141 0.021
amine metabolic process GO:0009308 44 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
circulatory system process GO:0003013 113 0.020
purine nucleoside catabolic process GO:0006152 398 0.020
cofactor metabolic process GO:0051186 87 0.020
negative regulation of cell death GO:0060548 345 0.019
defense response GO:0006952 315 0.019
metal ion transport GO:0030001 272 0.019
cellular response to endogenous stimulus GO:0071495 336 0.018
regulation of proteolysis GO:0030162 293 0.018
protein maturation GO:0051604 233 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
regulation of protein processing GO:0070613 150 0.018
response to other organism GO:0051707 261 0.018
cellular response to oxidative stress GO:0034599 85 0.018
regulation of ion transport GO:0043269 189 0.018
meiotic chromosome segregation GO:0045132 4 0.018
mitochondrial atp synthesis coupled electron transport GO:0042775 4 0.017
organic hydroxy compound biosynthetic process GO:1901617 71 0.017
bleb assembly GO:0032060 6 0.017
phospholipid metabolic process GO:0006644 99 0.017
organophosphate biosynthetic process GO:0090407 163 0.016
phototransduction GO:0007602 3 0.016
response to hypoxia GO:0001666 96 0.016
carbohydrate metabolic process GO:0005975 207 0.016
endothelial cell proliferation GO:0001935 65 0.016
immune response GO:0006955 307 0.015
cellular response to reactive oxygen species GO:0034614 50 0.015
nucleoside phosphate biosynthetic process GO:1901293 109 0.015
regulation of cysteine type endopeptidase activity GO:2000116 127 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
regulation of cellular amino acid metabolic process GO:0006521 6 0.015
regulation of peptide transport GO:0090087 62 0.015
heart process GO:0003015 62 0.015
muscle cell cellular homeostasis GO:0046716 3 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
purine ribonucleoside monophosphate biosynthetic process GO:0009168 16 0.015
glycerolipid metabolic process GO:0046486 107 0.014
regulation of atpase activity GO:0043462 25 0.014
neurological system process GO:0050877 163 0.014
apoptotic signaling pathway GO:0097190 268 0.014
cellular component morphogenesis GO:0032989 314 0.014
muscle cell differentiation GO:0042692 63 0.014
positive regulation of cell death GO:0010942 263 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
vesicle mediated transport GO:0016192 371 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
gtp catabolic process GO:0006184 237 0.013
metal ion homeostasis GO:0055065 169 0.013
regulation of lipid metabolic process GO:0019216 96 0.013
tissue regeneration GO:0042246 3 0.013
tissue homeostasis GO:0001894 63 0.013
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902177 4 0.013
ribose phosphate biosynthetic process GO:0046390 82 0.013
ion transmembrane transport GO:0034220 338 0.013
purine nucleoside monophosphate biosynthetic process GO:0009127 16 0.013
cell type specific apoptotic process GO:0097285 125 0.013
regulation of cellular component biogenesis GO:0044087 281 0.012
zymogen activation GO:0031638 70 0.012
response to abiotic stimulus GO:0009628 336 0.012
developmental process involved in reproduction GO:0003006 66 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
neuromuscular junction development GO:0007528 3 0.012
hemopoiesis GO:0030097 180 0.012
electron transport chain GO:0022900 8 0.012
cellular ion homeostasis GO:0006873 168 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
lipid storage GO:0019915 28 0.012
hydrogen transport GO:0006818 23 0.012
regulation of response to external stimulus GO:0032101 222 0.012
heart contraction GO:0060047 62 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
embryo development GO:0009790 123 0.012
negative regulation of apoptotic signaling pathway GO:2001234 97 0.012
alpha amino acid metabolic process GO:1901605 72 0.011
myeloid cell differentiation GO:0030099 117 0.011
behavioral defense response GO:0002209 0 0.011
anion transport GO:0006820 161 0.011
multi organism reproductive process GO:0044703 54 0.011
cell projection assembly GO:0030031 126 0.011
multicellular organismal homeostasis GO:0048871 67 0.011
cellular amino acid metabolic process GO:0006520 116 0.011
oxidative phosphorylation GO:0006119 10 0.011
cardiac muscle contraction GO:0060048 34 0.011
nitrogen compound transport GO:0071705 191 0.011
membrane organization GO:0061024 292 0.011
protein oligomerization GO:0051259 173 0.011
positive regulation of apoptotic signaling pathway GO:2001235 70 0.011
response to oxygen radical GO:0000305 6 0.011
response to lipid GO:0033993 206 0.011
organelle assembly GO:0070925 176 0.011
lung alveolus development GO:0048286 4 0.011
hindbrain development GO:0030902 3 0.011
rho protein signal transduction GO:0007266 26 0.011
regulation of peptidase activity GO:0052547 180 0.011
segmentation GO:0035282 4 0.011
fear response GO:0042596 0 0.011
myosin filament assembly GO:0031034 2 0.011
regulation of kinase activity GO:0043549 314 0.011
steroid metabolic process GO:0008202 94 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
cellular lipid catabolic process GO:0044242 65 0.011
blastoderm segmentation GO:0007350 2 0.010
cellular chemical homeostasis GO:0055082 180 0.010
regulation of gtp catabolic process GO:0033124 180 0.010
neuron death GO:0070997 65 0.010
negative regulation of cell proliferation GO:0008285 228 0.010
organic acid catabolic process GO:0016054 71 0.010
response to starvation GO:0042594 59 0.010
negative regulation of programmed cell death GO:0043069 321 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.010
nucleoside monophosphate biosynthetic process GO:0009124 19 0.010
response to drug GO:0042493 81 0.010
striated muscle myosin thick filament assembly GO:0071688 2 0.010
peptidyl serine modification GO:0018209 106 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010
response to organonitrogen compound GO:0010243 156 0.010

MDH1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.091
disease of cellular proliferation DOID:14566 174 0.091
disease of metabolism DOID:0014667 295 0.081
inherited metabolic disorder DOID:655 242 0.081
central nervous system disease DOID:331 186 0.040
nervous system disease DOID:863 431 0.040
organ system cancer DOID:0050686 164 0.033
carbohydrate metabolic disorder DOID:2978 55 0.025
cardiovascular system disease DOID:1287 106 0.021
amino acid metabolic disorder DOID:9252 50 0.020
organic acidemia DOID:0060159 14 0.020
myopathy DOID:423 104 0.020
muscular disease DOID:0080000 114 0.020
musculoskeletal system disease DOID:17 223 0.020
muscle tissue disease DOID:66 113 0.020
sensory system disease DOID:0050155 203 0.017
immune system disease DOID:2914 155 0.017
hematopoietic system disease DOID:74 100 0.017