Homo sapiens

66 known processes

MED21

mediator complex subunit 21

(Aliases: SRB7,SURB7)

MED21 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.936
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 0.895
dna templated transcription initiation GO:0006352 35 0.420
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.344
modification dependent macromolecule catabolic process GO:0043632 212 0.307
post embryonic development GO:0009791 2 0.281
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.241
cellular macromolecule catabolic process GO:0044265 380 0.222
protein localization to organelle GO:0033365 280 0.217
cellular response to dna damage stimulus GO:0006974 379 0.189
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.187
microtubule organizing center organization GO:0031023 62 0.183
mitotic cell cycle GO:0000278 326 0.183
proteasomal protein catabolic process GO:0010498 176 0.179
nervous system development GO:0007399 293 0.177
Worm
histone modification GO:0016570 251 0.162
cell cycle phase transition GO:0044770 173 0.160
regulation of mitotic cell cycle GO:0007346 189 0.157
oogenesis GO:0048477 2 0.154
regulation of cellular amino acid metabolic process GO:0006521 6 0.152
modification dependent protein catabolic process GO:0019941 209 0.151
internal peptidyl lysine acetylation GO:0018393 97 0.147
protein modification by small protein conjugation GO:0032446 342 0.140
regulation of kinase activity GO:0043549 314 0.140
ubiquitin dependent protein catabolic process GO:0006511 206 0.134
intracellular receptor signaling pathway GO:0030522 104 0.126
negative regulation of cell cycle phase transition GO:1901988 89 0.122
immune response GO:0006955 307 0.121
androgen receptor signaling pathway GO:0030521 34 0.118
cellular macromolecular complex assembly GO:0034622 324 0.117
lung saccule development GO:0060430 2 0.108
negative regulation of cell proliferation GO:0008285 228 0.102
chromatin organization GO:0006325 351 0.102
positive regulation of phosphorylation GO:0042327 394 0.101
cytoplasmic transport GO:0016482 379 0.100
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.098
female gamete generation GO:0007292 2 0.098
receptor mediated endocytosis GO:0006898 84 0.096
negative regulation of multicellular organismal process GO:0051241 317 0.095
regulation of transferase activity GO:0051338 355 0.092
peptidyl lysine acetylation GO:0018394 101 0.092
regulation of neural precursor cell proliferation GO:2000177 4 0.089
protein catabolic process GO:0030163 325 0.085
regulation of cellular amine metabolic process GO:0033238 11 0.082
secretion GO:0046903 254 0.081
regulation of cell cycle GO:0051726 393 0.081
mitotic cell cycle process GO:1903047 286 0.081
meiotic chromosome segregation GO:0045132 4 0.080
cellular response to endogenous stimulus GO:0071495 336 0.078
negative regulation of protein metabolic process GO:0051248 391 0.076
negative regulation of cellular component organization GO:0051129 235 0.073
cell development GO:0048468 328 0.071
Mouse Worm
regulation of protein catabolic process GO:0042176 155 0.070
protein targeting GO:0006605 187 0.069
innate immune response GO:0045087 178 0.068
negative regulation of cell differentiation GO:0045596 171 0.067
Mouse
regulation of establishment of protein localization GO:0070201 242 0.067
cellular amine metabolic process GO:0044106 41 0.065
regulation of protein localization GO:0032880 296 0.062
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.062
endocytosis GO:0006897 159 0.061
regulation of mitotic cell cycle phase transition GO:1901990 118 0.061
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.060
cellular protein complex assembly GO:0043623 188 0.059
dna repair GO:0006281 198 0.058
negative regulation of immune system process GO:0002683 136 0.055
negative regulation of developmental process GO:0051093 247 0.054
Mouse
internal protein amino acid acetylation GO:0006475 101 0.054
negative regulation of neurogenesis GO:0050768 26 0.053
negative regulation of cellular protein metabolic process GO:0032269 353 0.052
neuroblast proliferation GO:0007405 4 0.052
regulation of secretion GO:0051046 194 0.052
response to abiotic stimulus GO:0009628 336 0.051
defense response GO:0006952 315 0.051
regulation of cell development GO:0060284 161 0.051
regulation of intracellular transport GO:0032386 195 0.050
reproductive process GO:0022414 106 0.050
mapk cascade GO:0000165 288 0.049
rna interference GO:0016246 4 0.049
protein ubiquitination GO:0016567 314 0.049
regulation of cell cycle process GO:0010564 266 0.049
cellular protein catabolic process GO:0044257 261 0.047
regulation of proteasomal protein catabolic process GO:0061136 87 0.047
intracellular protein transport GO:0006886 270 0.047
negative regulation of chromosome organization GO:2001251 48 0.046
centrosome organization GO:0051297 58 0.045
covalent chromatin modification GO:0016569 254 0.043
chromatin modification GO:0016568 298 0.043
mitotic cell cycle phase transition GO:0044772 162 0.041
regulation of cell cycle phase transition GO:1901987 126 0.041
amine metabolic process GO:0009308 44 0.040
regulation of protein serine threonine kinase activity GO:0071900 179 0.040
circulatory system development GO:0072359 262 0.040
response to fungus GO:0009620 4 0.039
regulation of cellular protein catabolic process GO:1903362 96 0.039
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.039
organelle assembly GO:0070925 176 0.038
nuclear division GO:0000280 128 0.038
regulation of neuroblast proliferation GO:1902692 3 0.038
peptidyl lysine modification GO:0018205 144 0.037
nitrogen compound transport GO:0071705 191 0.037
protein import into nucleus GO:0006606 104 0.037
regulation of protein kinase activity GO:0045859 289 0.036
response to external biotic stimulus GO:0043207 261 0.034
negative regulation of protein catabolic process GO:0042177 59 0.034
embryo development GO:0009790 123 0.034
Mouse
striated muscle tissue development GO:0014706 59 0.033
spermatid development GO:0007286 4 0.033
embryo development ending in birth or egg hatching GO:0009792 34 0.033
Mouse
single organism reproductive process GO:0044702 98 0.032
regulation of gene expression epigenetic GO:0040029 73 0.032
establishment of protein localization to organelle GO:0072594 172 0.032
reproduction GO:0000003 63 0.031
gene silencing GO:0016458 49 0.031
protein processing GO:0016485 226 0.031
signal transduction by phosphorylation GO:0023014 297 0.031
regulation of chromosome organization GO:0033044 103 0.031
protein import GO:0017038 130 0.030
meiosis i GO:0007127 4 0.030
nuclear transport GO:0051169 179 0.029
cellular component morphogenesis GO:0032989 314 0.029
negative regulation of phosphorylation GO:0042326 174 0.029
positive regulation of catabolic process GO:0009896 310 0.028
regulation of immune response GO:0050776 201 0.028
sensory organ development GO:0007423 52 0.027
regulation of protein maturation GO:1903317 150 0.027
posttranscriptional regulation of gene expression GO:0010608 213 0.027
negative regulation of programmed cell death GO:0043069 321 0.027
negative regulation of organelle organization GO:0010639 126 0.026
negative regulation of mapk cascade GO:0043409 56 0.026
microtubule polymerization or depolymerization GO:0031109 37 0.026
neurogenesis GO:0022008 169 0.026
Worm
defense response to bacterium GO:0042742 63 0.026
lipid biosynthetic process GO:0008610 177 0.026
response to other organism GO:0051707 261 0.025
cardiac muscle tissue development GO:0048738 39 0.025
endosomal transport GO:0016197 129 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
cardiovascular system development GO:0072358 262 0.025
cellular amino acid metabolic process GO:0006520 116 0.024
response to oxygen containing compound GO:1901700 369 0.024
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
negative regulation of protein maturation GO:1903318 142 0.024
nuclear import GO:0051170 106 0.023
lipid metabolic process GO:0006629 381 0.023
regulation of intracellular protein transport GO:0033157 123 0.023
cell projection morphogenesis GO:0048858 129 0.022
cellular ketone metabolic process GO:0042180 80 0.022
regulation of meiosis GO:0040020 3 0.022
vesicle mediated transport GO:0016192 371 0.022
protein targeting to nucleus GO:0044744 104 0.022
negative regulation of protein processing GO:0010955 142 0.022
negative regulation of apoptotic process GO:0043066 316 0.022
rna processing GO:0006396 255 0.021
single organism cellular localization GO:1902580 332 0.021
reproductive system development GO:0061458 56 0.021
regulation of mapk cascade GO:0043408 262 0.021
developmental process involved in reproduction GO:0003006 66 0.020
segmentation GO:0035282 4 0.020
positive regulation of cell cycle GO:0045787 140 0.020
cell morphogenesis GO:0000902 296 0.020
gene silencing by rna GO:0031047 26 0.020
regulation of anatomical structure morphogenesis GO:0022603 286 0.020
spindle assembly GO:0051225 29 0.020
microtubule based process GO:0007017 210 0.020
carbohydrate metabolic process GO:0005975 207 0.020
regulation of map kinase activity GO:0043405 108 0.020
negative regulation of cell development GO:0010721 48 0.020
chromosome separation GO:0051304 23 0.020
organophosphate biosynthetic process GO:0090407 163 0.019
double strand break repair GO:0006302 101 0.019
protein dna complex assembly GO:0065004 64 0.019
regulation of protein processing GO:0070613 150 0.019
regulation of protein secretion GO:0050708 86 0.019
response to radiation GO:0009314 151 0.019
regulation of protein targeting GO:1903533 91 0.018
chromosome segregation GO:0007059 114 0.018
negative regulation of cellular protein catabolic process GO:1903363 38 0.018
associative learning GO:0008306 1 0.018
establishment of nucleus localization GO:0040023 1 0.018
regeneration GO:0031099 4 0.018
histone ubiquitination GO:0016574 31 0.018
mitotic nuclear division GO:0007067 119 0.018
regulation of protein transport GO:0051223 213 0.018
oocyte differentiation GO:0009994 2 0.018
cell division GO:0051301 168 0.018
regulation of cell morphogenesis GO:0022604 153 0.018
dna damage checkpoint GO:0000077 68 0.018
negative regulation of cell death GO:0060548 345 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
protein acetylation GO:0006473 116 0.017
regulation of defense response GO:0031347 154 0.017
nucleus localization GO:0051647 1 0.017
protein maturation GO:0051604 233 0.017
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.017
histone acetylation GO:0016573 93 0.017
regulation of protein localization to nucleus GO:1900180 85 0.016
nuclear transcribed mrna catabolic process GO:0000956 48 0.016
negative regulation of cell cycle GO:0045786 193 0.016
positive regulation of transferase activity GO:0051347 227 0.016
positive regulation of transport GO:0051050 336 0.016
negative regulation of mitotic cell cycle GO:0045930 102 0.016
positive regulation of cell death GO:0010942 263 0.016
negative regulation of proteolysis GO:0045861 132 0.016
metaphase anaphase transition of cell cycle GO:0044784 21 0.016
positive regulation of organelle organization GO:0010638 195 0.015
central nervous system development GO:0007417 123 0.015
mitotic cell cycle checkpoint GO:0007093 68 0.015
multicellular organismal response to stress GO:0033555 1 0.015
spindle organization GO:0007051 53 0.015
regulation of chromatin organization GO:1902275 56 0.015
negative regulation of cell cycle process GO:0010948 121 0.015
generation of neurons GO:0048699 152 0.015
Worm
cellular response to oxygen containing compound GO:1901701 276 0.015
nucleocytoplasmic transport GO:0006913 176 0.015
positive regulation of cell differentiation GO:0045597 211 0.015
negative regulation of nervous system development GO:0051961 28 0.015
regulation of organelle assembly GO:1902115 40 0.015
negative regulation of growth GO:0045926 97 0.015
regulation of growth GO:0040008 165 0.015
response to hormone GO:0009725 175 0.014
purine ribonucleoside metabolic process GO:0046128 437 0.014
dna templated transcriptional preinitiation complex assembly GO:0070897 5 0.014
rna 3 end processing GO:0031123 35 0.014
nucleoside catabolic process GO:0009164 408 0.014
ncrna metabolic process GO:0034660 108 0.014
regulation of cell division GO:0051302 116 0.014
retrograde transport endosome to golgi GO:0042147 45 0.014
protein acylation GO:0043543 138 0.014
regulation of cell differentiation GO:0045595 393 0.013
Mouse
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.013
negative regulation of protein modification process GO:0031400 200 0.013
mrna metabolic process GO:0016071 175 0.013
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.013
purine ribonucleoside catabolic process GO:0046130 398 0.013
single organism membrane organization GO:0044802 268 0.013
cell part morphogenesis GO:0032990 137 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
nucleotide catabolic process GO:0009166 408 0.013
centrosome cycle GO:0007098 32 0.012
regulation of chromosome segregation GO:0051983 44 0.012
negative regulation of kinase activity GO:0033673 106 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
regulation of secretion by cell GO:1903530 177 0.012
negative regulation of catalytic activity GO:0043086 335 0.012
dna integrity checkpoint GO:0031570 71 0.012
regulation of neurogenesis GO:0050767 82 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
lung alveolus development GO:0048286 4 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
protein polyubiquitination GO:0000209 110 0.012
negative regulation of catabolic process GO:0009895 104 0.012
regulation of cellular response to stress GO:0080135 244 0.012
response to biotic stimulus GO:0009607 276 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
male gamete generation GO:0048232 22 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
neuron differentiation GO:0030182 138 0.012
Worm
response to alcohol GO:0097305 64 0.012
anterior posterior axis specification GO:0009948 2 0.011
response to drug GO:0042493 81 0.011
regulation of protein stability GO:0031647 87 0.011
macromolecule methylation GO:0043414 97 0.011
muscle tissue development GO:0060537 62 0.011
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.011
mitotic sister chromatid segregation GO:0000070 53 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
mitochondrial transport GO:0006839 60 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
mrna splicing via spliceosome GO:0000398 89 0.011
regulation of cellular ketone metabolic process GO:0010565 50 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
epithelium development GO:0060429 227 0.011
protein localization to nucleus GO:0034504 136 0.011
microtubule polymerization GO:0046785 18 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.011
defense response to fungus GO:0050832 4 0.011
purine containing compound catabolic process GO:0072523 411 0.011
rna localization GO:0006403 41 0.011
mitotic sister chromatid separation GO:0051306 18 0.011
eye photoreceptor cell differentiation GO:0001754 2 0.011
cellular response to nutrient levels GO:0031669 69 0.010
posttranscriptional gene silencing by rna GO:0035194 25 0.010
embryonic placenta development GO:0001892 1 0.010
neuron development GO:0048666 113 0.010
Worm
organophosphate catabolic process GO:0046434 430 0.010

MED21 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.017
nervous system disease DOID:863 431 0.017