|
|
positive regulation of interleukin 1 beta secretion
|
GO:0050718 |
11 |
0.457
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.391
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
13 |
0.273
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.258
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
14 |
0.242
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.230
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.225
|
|
|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
18 |
0.224
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.217
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.215
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.213
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.205
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.203
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.203
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.198
|
|
|
|
positive regulation of interleukin 8 secretion
|
GO:2000484 |
9 |
0.191
|
|
|
|
negative regulation of interferon beta production
|
GO:0032688 |
4 |
0.190
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.189
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.188
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.187
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.177
|
|
|
|
detection of muramyl dipeptide
|
GO:0032498 |
1 |
0.169
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.166
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.165
|
Rat |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.165
|
|
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
30 |
0.165
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.159
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.159
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.157
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.156
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.156
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.154
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.154
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.152
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.151
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.150
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.148
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.148
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.144
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.143
|
|
|
|
positive regulation of t cell migration
|
GO:2000406 |
13 |
0.142
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.142
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
18 |
0.141
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.140
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.138
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.136
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.135
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.134
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.132
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.131
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.130
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.130
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.129
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.127
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
36 |
0.126
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.125
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.125
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.124
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.123
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.123
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.121
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.120
|
Rat |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.120
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.119
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.119
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.119
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.119
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.118
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.118
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.117
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.115
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.114
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.113
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.112
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.111
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.111
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.111
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.111
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.110
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.110
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.110
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
21 |
0.109
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.109
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.109
|
Rat |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.107
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
15 |
0.106
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.106
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.106
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.105
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.105
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.105
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.105
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.103
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.103
|
|
|
|
pinocytosis
|
GO:0006907 |
8 |
0.103
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.103
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.103
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.102
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.102
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.102
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.101
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.101
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.100
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.100
|
|
|
|
interferon beta production
|
GO:0032608 |
23 |
0.099
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.099
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.098
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.098
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.097
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.097
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.097
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
12 |
0.096
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.096
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.095
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.094
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.094
|
|
|
|
positive regulation of interleukin 1 production
|
GO:0032732 |
14 |
0.094
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.094
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.093
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.093
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.093
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.092
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
4 |
0.092
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.091
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.091
|
Rat |
|
|
chemokine production
|
GO:0032602 |
32 |
0.091
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.090
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.090
|
Rat |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.090
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.090
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.089
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.089
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.089
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.089
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.088
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.088
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.087
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.087
|
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.087
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.087
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.086
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.086
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.086
|
Rat |
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.085
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.085
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.085
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.085
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.084
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.083
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.083
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.083
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.083
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.083
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.083
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.082
|
|
|
|
regulation of t cell migration
|
GO:2000404 |
14 |
0.082
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.082
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.082
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.081
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.081
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.079
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.078
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.078
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.078
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.077
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.076
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.076
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.076
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.076
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.076
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.076
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.075
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.075
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.075
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.075
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.075
|
|
|
|
positive regulation of interleukin 10 secretion
|
GO:2001181 |
2 |
0.074
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.074
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.074
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.074
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.073
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.073
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.073
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.073
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.072
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.072
|
|
|
|
regulation of interferon beta production
|
GO:0032648 |
22 |
0.071
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.071
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.071
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.070
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.070
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.070
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.070
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.069
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.069
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.068
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.068
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.068
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.068
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.067
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.066
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
15 |
0.066
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.066
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.066
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.066
|
|
|
|
t cell migration
|
GO:0072678 |
16 |
0.065
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.065
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.064
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.064
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.064
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.064
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.063
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.063
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
18 |
0.063
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.063
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.062
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
22 |
0.062
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.062
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.062
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.061
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.061
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.061
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.061
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.061
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.061
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.060
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.060
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.060
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.060
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.060
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.060
|
|
|
|
antigen processing and presentation of peptide antigen via mhc class ii
|
GO:0002495 |
11 |
0.060
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
16 |
0.059
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.059
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.059
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.059
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.058
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.058
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.058
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.057
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.057
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.057
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.057
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.057
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.056
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.056
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.056
|
|
|
|
positive regulation of antigen processing and presentation
|
GO:0002579 |
1 |
0.055
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.055
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.054
|
|
|
|
regulation of interleukin 1 secretion
|
GO:0050704 |
14 |
0.054
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.054
|
|
|
|
positive regulation of interleukin 1 beta production
|
GO:0032731 |
13 |
0.053
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.052
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.052
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.051
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.051
|
|
|
|
activated t cell proliferation
|
GO:0050798 |
13 |
0.050
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.049
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.049
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
29 |
0.049
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.049
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.049
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.048
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.048
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.048
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.048
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.048
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.047
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.047
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.047
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.047
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.047
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
37 |
0.047
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.046
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.045
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.045
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.045
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
33 |
0.045
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.044
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
21 |
0.044
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.043
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.043
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.043
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.043
|
|
|
|
regulation of type i interferon production
|
GO:0032479 |
26 |
0.043
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.042
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.042
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.042
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.041
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.041
|
|
|
|
type i interferon production
|
GO:0032606 |
27 |
0.040
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.039
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.039
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.039
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.039
|
|
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
14 |
0.038
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.038
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.038
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.037
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.037
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.036
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.036
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.036
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.036
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.036
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.035
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.035
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.035
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.035
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.034
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.034
|
|
|
|
regulation of tumor necrosis factor mediated signaling pathway
|
GO:0010803 |
12 |
0.034
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.034
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.034
|
|
|
|
interleukin 1 production
|
GO:0032612 |
26 |
0.034
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.034
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.033
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.033
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.033
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.033
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.033
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.032
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.032
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.032
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.032
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.032
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.031
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.031
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.031
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.030
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.030
|
|
|
|
positive regulation of interleukin 6 secretion
|
GO:2000778 |
6 |
0.030
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.030
|
Rat |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.030
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.030
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.029
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.029
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.029
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.029
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.028
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.028
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.027
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.027
|
|
|
|
regulation of rac gtpase activity
|
GO:0032314 |
4 |
0.027
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.026
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.026
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.026
|
|
|
|
antigen processing and presentation of peptide antigen
|
GO:0048002 |
18 |
0.026
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.026
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.025
|
|
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
11 |
0.025
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.025
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.025
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.025
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.025
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.025
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.024
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.024
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.024
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.024
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.024
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.024
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.023
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.023
|
|
|
|
interleukin 10 production
|
GO:0032613 |
17 |
0.023
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.023
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.023
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.023
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.022
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.022
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
16 |
0.022
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.022
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.022
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.021
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.021
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.021
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.021
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.021
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.020
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.020
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.020
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.020
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.020
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.019
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.019
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.019
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.019
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.019
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.019
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.019
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.019
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
21 |
0.019
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.019
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.019
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.019
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.019
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.018
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.018
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.018
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.018
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.018
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.018
|
|
|
|
regulation of eosinophil activation
|
GO:1902566 |
2 |
0.018
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.018
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.018
|
Rat |
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.018
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
27 |
0.018
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.018
|
|
|
|
phagocytosis
|
GO:0006909 |
42 |
0.017
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.017
|
|
|
|
negative regulation of type i interferon production
|
GO:0032480 |
5 |
0.017
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.017
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.017
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.017
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.017
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.017
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.017
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.017
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.017
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.016
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.016
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.016
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.016
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.016
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.016
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.016
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.016
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.016
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.016
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.016
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.016
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.016
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.016
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.016
|
|
|
|
system process
|
GO:0003008 |
349 |
0.016
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.016
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.015
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.015
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.015
|
|
|
|
negative regulation of acetylcholine gated cation channel activity
|
GO:1903049 |
1 |
0.015
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
29 |
0.015
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.015
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.015
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.015
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.015
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.015
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.015
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.015
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.015
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.015
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.015
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.015
|
|
|
|
visual learning
|
GO:0008542 |
1 |
0.015
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.015
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.015
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.015
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.015
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.015
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.015
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.015
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.014
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.014
|
|
|
|
memory
|
GO:0007613 |
3 |
0.014
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.014
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.014
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.014
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
10 |
0.014
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.014
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.014
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.014
|
|
|
|
growth
|
GO:0040007 |
202 |
0.014
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.014
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.014
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.014
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.014
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.014
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.014
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.014
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.014
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.014
|
|
