Homo sapiens

244 known processes

MEN1

multiple endocrine neoplasia I

(Aliases: MEAI,MENIN,SCG2)

MEN1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin organization GO:0006325 351 0.980
histone lysine methylation GO:0034968 50 0.953
peptidyl lysine modification GO:0018205 144 0.941
histone modification GO:0016570 251 0.926
chromatin modification GO:0016568 298 0.920
cellular response to dna damage stimulus GO:0006974 379 0.872
cellular ketone metabolic process GO:0042180 80 0.859
histone h3 acetylation GO:0043966 45 0.807
histone methylation GO:0016571 60 0.803
internal peptidyl lysine acetylation GO:0018393 97 0.802
cellular amino acid metabolic process GO:0006520 116 0.758
histone h4 k8 acetylation GO:0043982 15 0.752
protein acetylation GO:0006473 116 0.727
regulation of cellular amino acid metabolic process GO:0006521 6 0.693
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.628
peptidyl lysine acetylation GO:0018394 101 0.612
immune system development GO:0002520 195 0.600
Mouse
amine metabolic process GO:0009308 44 0.567
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.562
response to abiotic stimulus GO:0009628 336 0.558
regulation of cellular ketone metabolic process GO:0010565 50 0.552
response to biotic stimulus GO:0009607 276 0.518
covalent chromatin modification GO:0016569 254 0.517
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.470
histone h4 k16 acetylation GO:0043984 14 0.453
peptidyl lysine methylation GO:0018022 37 0.402
internal protein amino acid acetylation GO:0006475 101 0.389
cardiovascular system development GO:0072358 262 0.389
peptidyl lysine dimethylation GO:0018027 3 0.377
response to lipid GO:0033993 206 0.375
posttranscriptional regulation of gene expression GO:0010608 213 0.367
defense response GO:0006952 315 0.343
cellular amine metabolic process GO:0044106 41 0.339
negative regulation of multicellular organismal process GO:0051241 317 0.336
vasculature development GO:0001944 181 0.296
methylation GO:0032259 106 0.295
hematopoietic or lymphoid organ development GO:0048534 186 0.278
Mouse
immune response GO:0006955 307 0.277
multicellular organismal aging GO:0010259 3 0.277
regulation of response to dna damage stimulus GO:2001020 94 0.263
positive regulation of cellular amine metabolic process GO:0033240 7 0.256
protein modification by small protein conjugation GO:0032446 342 0.255
negative regulation of apoptotic process GO:0043066 316 0.246
regulation of gene expression epigenetic GO:0040029 73 0.241
protein acylation GO:0043543 138 0.241
regulation of response to external stimulus GO:0032101 222 0.238
protein alkylation GO:0008213 74 0.235
innate immune response GO:0045087 178 0.220
protein ubiquitination GO:0016567 314 0.220
histone acetylation GO:0016573 93 0.219
response to other organism GO:0051707 261 0.215
organ morphogenesis GO:0009887 147 0.211
Mouse
macromolecule methylation GO:0043414 97 0.205
regulation of cellular amine metabolic process GO:0033238 11 0.187
dna repair GO:0006281 198 0.183
regulation of cellular response to stress GO:0080135 244 0.176
transdifferentiation GO:0060290 2 0.171
female gamete generation GO:0007292 2 0.171
positive regulation of cytokine production GO:0001819 167 0.157
mitotic cell cycle process GO:1903047 286 0.151
post embryonic development GO:0009791 2 0.144
cellular response to organic cyclic compound GO:0071407 127 0.144
anatomical structure formation involved in morphogenesis GO:0048646 284 0.143
histone h3 k4 trimethylation GO:0080182 7 0.142
protein processing GO:0016485 226 0.141
hemopoiesis GO:0030097 180 0.131
Mouse
histone h4 acetylation GO:0043967 47 0.128
cation transport GO:0006812 331 0.126
blood vessel development GO:0001568 172 0.117
regulation of defense response GO:0031347 154 0.102
response to hormone GO:0009725 175 0.101
jak stat cascade GO:0007259 46 0.098
response to cytokine GO:0034097 232 0.097
response to organic cyclic compound GO:0014070 204 0.096
determination of adult lifespan GO:0008340 2 0.095
histone h3 k4 methylation GO:0051568 27 0.094
regulation of protein stability GO:0031647 87 0.092
negative regulation of protein metabolic process GO:0051248 391 0.092
regulation of dna repair GO:0006282 47 0.090
oocyte differentiation GO:0009994 2 0.088
viral latency GO:0019042 1 0.088
cellular response to oxygen containing compound GO:1901701 276 0.087
cellular response to abiotic stimulus GO:0071214 117 0.087
embryo development GO:0009790 123 0.081
Mouse
spermatid development GO:0007286 4 0.080
response to bacterium GO:0009617 144 0.080
defense response to other organism GO:0098542 129 0.079
compound eye development GO:0048749 1 0.073
cytokine production GO:0001816 247 0.070
regulation of cysteine type endopeptidase activity GO:2000116 127 0.070
Mouse
nervous system development GO:0007399 293 0.068
regulation of cell differentiation GO:0045595 393 0.067
negative regulation of defense response GO:0031348 47 0.067
protein stabilization GO:0050821 64 0.066
positive regulation of programmed cell death GO:0043068 249 0.066
Mouse
regulation of protein processing GO:0070613 150 0.065
regulation of transferase activity GO:0051338 355 0.064
negative regulation of cell cycle GO:0045786 193 0.062
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.062
regulation of cell cycle GO:0051726 393 0.061
lipid metabolic process GO:0006629 381 0.057
histone h4 k5 acetylation GO:0043981 15 0.055
signal transduction in response to dna damage GO:0042770 57 0.055
gene silencing GO:0016458 49 0.053
response to external biotic stimulus GO:0043207 261 0.052
neural tube formation GO:0001841 3 0.052
mitotic cell cycle GO:0000278 326 0.051
cellular response to cytokine stimulus GO:0071345 181 0.051
negative regulation of developmental process GO:0051093 247 0.051
negative regulation of programmed cell death GO:0043069 321 0.051
regulation of chromosome organization GO:0033044 103 0.051
Mouse
response to oxygen containing compound GO:1901700 369 0.050
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.048
regulation of immune effector process GO:0002697 91 0.048
lipid biosynthetic process GO:0008610 177 0.047
morphogenesis of embryonic epithelium GO:0016331 4 0.046
dna methylation or demethylation GO:0044728 19 0.046
cellular response to lipid GO:0071396 127 0.046
regulation of dna metabolic process GO:0051052 153 0.045
defense response to bacterium GO:0042742 63 0.045
cell development GO:0048468 328 0.045
intrinsic apoptotic signaling pathway GO:0097193 127 0.045
segmentation GO:0035282 4 0.045
establishment of t cell polarity GO:0001768 2 0.045
cellular lipid metabolic process GO:0044255 303 0.044
oocyte development GO:0048599 1 0.044
protein methylation GO:0006479 74 0.044
cellular component morphogenesis GO:0032989 314 0.044
central nervous system development GO:0007417 123 0.044
neurogenesis GO:0022008 169 0.044
myeloid cell differentiation GO:0030099 117 0.043
response to radiation GO:0009314 151 0.043
positive regulation of immune response GO:0050778 159 0.043
cellular protein catabolic process GO:0044257 261 0.042
protein autophosphorylation GO:0046777 123 0.042
positive regulation of proteolysis GO:0045862 142 0.042
Mouse
carbohydrate biosynthetic process GO:0016051 42 0.041
chromatin silencing GO:0006342 12 0.040
cellular ion homeostasis GO:0006873 168 0.040
single organism reproductive process GO:0044702 98 0.039
Mouse
neuron differentiation GO:0030182 138 0.039
negative regulation of cell cycle process GO:0010948 121 0.039
nucleotide excision repair GO:0006289 31 0.039
negative regulation of response to external stimulus GO:0032102 83 0.038
organelle fission GO:0048285 149 0.038
regulation of multi organism process GO:0043900 157 0.037
growth GO:0040007 202 0.037
Mouse
negative regulation of cytokine production GO:0001818 82 0.037
erythrocyte development GO:0048821 3 0.037
positive regulation of immune system process GO:0002684 283 0.036
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter GO:0072366 1 0.036
locomotory behavior GO:0007626 1 0.036
positive regulation of response to external stimulus GO:0032103 88 0.036
cell cycle checkpoint GO:0000075 117 0.035
vesicle mediated transport GO:0016192 371 0.035
positive regulation of histone modification GO:0031058 29 0.035
Mouse
cellular homeostasis GO:0019725 196 0.035
negative regulation of cell death GO:0060548 345 0.035
double strand break repair GO:0006302 101 0.034
positive regulation of cell death GO:0010942 263 0.034
Mouse
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.034
carbohydrate metabolic process GO:0005975 207 0.033
aging GO:0007568 66 0.033
positive regulation of phosphorylation GO:0042327 394 0.032
organonitrogen compound biosynthetic process GO:1901566 200 0.032
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.032
cellular response to endogenous stimulus GO:0071495 336 0.032
regulation of histone modification GO:0031056 47 0.032
Mouse
somitogenesis GO:0001756 2 0.032
cellular response to hormone stimulus GO:0032870 125 0.032
dna methylation GO:0006306 7 0.032
response to molecule of bacterial origin GO:0002237 82 0.031
mitotic dna damage checkpoint GO:0044773 28 0.031
positive regulation of chromosome organization GO:2001252 41 0.031
Mouse
antimicrobial humoral response GO:0019730 26 0.031
regulation of protein ubiquitination GO:0031396 95 0.031
generation of neurons GO:0048699 152 0.030
protein glycosylation GO:0006486 62 0.030
regulation of innate immune response GO:0045088 97 0.030
regulation of protein catabolic process GO:0042176 155 0.030
response to nitrogen compound GO:1901698 184 0.030
neuron development GO:0048666 113 0.029
regulation of chromatin modification GO:1903308 51 0.029
Mouse
circadian behavior GO:0048512 2 0.029
spermatid differentiation GO:0048515 4 0.029
negative regulation of proteolysis GO:0045861 132 0.029
blood vessel morphogenesis GO:0048514 162 0.029
regulation of histone acetylation GO:0035065 19 0.029
tube development GO:0035295 125 0.029
maintenance of location GO:0051235 112 0.028
chemotaxis GO:0006935 157 0.028
regulation of antimicrobial humoral response GO:0002759 1 0.028
regulation of cell cycle process GO:0010564 266 0.028
regulation of chromatin organization GO:1902275 56 0.028
Mouse
reproductive process GO:0022414 106 0.027
Mouse
proteasomal protein catabolic process GO:0010498 176 0.027
circulatory system development GO:0072359 262 0.027
dna modification GO:0006304 27 0.027
dna replication GO:0006260 116 0.027
single organism carbohydrate metabolic process GO:0044723 193 0.026
embryonic hemopoiesis GO:0035162 4 0.026
positive regulation of transport GO:0051050 336 0.026
pharynx development GO:0060465 1 0.026
peptidyl lysine monomethylation GO:0018026 4 0.025
mitotic cell cycle phase transition GO:0044772 162 0.025
cell projection organization GO:0030030 252 0.024
dna templated transcription initiation GO:0006352 35 0.024
actin filament based process GO:0030029 224 0.024
positive regulation of organelle organization GO:0010638 195 0.024
Mouse
chemical homeostasis GO:0048878 306 0.024
positive regulation of cytoplasmic transport GO:1903651 82 0.023
epithelium migration GO:0090132 119 0.023
regulation of response to biotic stimulus GO:0002831 55 0.023
cell cycle phase transition GO:0044770 173 0.023
modification dependent protein catabolic process GO:0019941 209 0.023
protein modification by small protein removal GO:0070646 92 0.023
cytokine mediated signaling pathway GO:0019221 109 0.023
cell projection morphogenesis GO:0048858 129 0.023
regulation of establishment of protein localization GO:0070201 242 0.023
multicellular organism reproduction GO:0032504 42 0.023
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.022
chromatin mediated maintenance of transcription GO:0048096 2 0.022
regulation of cellular response to drug GO:2001038 2 0.022
cellular response to biotic stimulus GO:0071216 71 0.022
oogenesis GO:0048477 2 0.021
dna integrity checkpoint GO:0031570 71 0.021
regulation of immune response GO:0050776 201 0.021
endocytosis GO:0006897 159 0.021
mitotic nuclear division GO:0007067 119 0.020
response to decreased oxygen levels GO:0036293 96 0.020
regulation of protein acetylation GO:1901983 25 0.020
peptidyl tyrosine modification GO:0018212 170 0.020
regulation of dna replication GO:0006275 68 0.020
tube morphogenesis GO:0035239 95 0.020
regulation of cytokine production GO:0001817 232 0.019
ion homeostasis GO:0050801 230 0.019
tissue morphogenesis GO:0048729 96 0.019
neuron projection morphogenesis GO:0048812 50 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
neural tube closure GO:0001843 3 0.019
immune effector process GO:0002252 159 0.019
response to lipopolysaccharide GO:0032496 70 0.019
negative regulation of protein processing GO:0010955 142 0.019
developmental growth GO:0048589 48 0.019
Mouse
rhythmic behavior GO:0007622 2 0.019
mitochondrion organization GO:0007005 156 0.019
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.019
peptidyl tyrosine phosphorylation GO:0018108 170 0.018
maintenance of protein location GO:0045185 57 0.018
embryonic epithelial tube formation GO:0001838 4 0.018
sexual reproduction GO:0019953 37 0.018
trophectodermal cell differentiation GO:0001829 3 0.018
peptidyl lysine trimethylation GO:0018023 10 0.018
somatic stem cell maintenance GO:0035019 4 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
positive regulation of protein phosphorylation GO:0001934 313 0.018
regulation of protein localization GO:0032880 296 0.018
cell aging GO:0007569 52 0.018
chromosome segregation GO:0007059 114 0.017
regulation of peptidase activity GO:0052547 180 0.017
Mouse
positive regulation of endopeptidase activity GO:0010950 84 0.017
Mouse
blastoderm segmentation GO:0007350 2 0.017
apoptotic signaling pathway GO:0097190 268 0.017
digestive tract development GO:0048565 75 0.017
blastocyst development GO:0001824 3 0.017
signal transduction by p53 class mediator GO:0072331 72 0.017
purine ribonucleoside metabolic process GO:0046128 437 0.017
regulation of cytoplasmic transport GO:1903649 149 0.017
response to light stimulus GO:0009416 87 0.017
morphogenesis of a polarized epithelium GO:0001738 3 0.016
negative regulation of endopeptidase activity GO:0010951 84 0.016
regulation of peptidyl lysine acetylation GO:2000756 22 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
glycoprotein biosynthetic process GO:0009101 91 0.016
regulation of cell division GO:0051302 116 0.016
Mouse
photoreceptor cell differentiation GO:0046530 2 0.016
regulation of protein transport GO:0051223 213 0.016
maintenance of location in cell GO:0051651 62 0.016
cell morphogenesis GO:0000902 296 0.016
neuron projection development GO:0031175 106 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.016
toll signaling pathway GO:0008063 2 0.016
sex determination GO:0007530 3 0.016
positive regulation of peptidase activity GO:0010952 88 0.016
Mouse
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
negative regulation of cellular protein metabolic process GO:0032269 353 0.016
multi organism reproductive process GO:0044703 54 0.016
Mouse
central nervous system projection neuron axonogenesis GO:0021952 3 0.015
gastrulation GO:0007369 51 0.015
heart morphogenesis GO:0003007 48 0.015
response to oxygen levels GO:0070482 100 0.015
regulation of protein maturation GO:1903317 150 0.015
metencephalon development GO:0022037 2 0.015
dna biosynthetic process GO:0071897 40 0.015
transmembrane transport GO:0055085 399 0.015
protein maturation GO:0051604 233 0.015
negative regulation of response to wounding GO:1903035 47 0.015
positive regulation of dna templated transcription elongation GO:0032786 18 0.015
establishment of planar polarity GO:0001736 3 0.015
anterior posterior axis specification GO:0009948 2 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
response to acid chemical GO:0001101 66 0.015
protein deubiquitination GO:0016579 79 0.015
regulation of protein kinase activity GO:0045859 289 0.015
leukocyte activation GO:0045321 164 0.014
response to wounding GO:0009611 168 0.014
regionalization GO:0003002 29 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
Mouse
gamete generation GO:0007276 25 0.014
regulation of double strand break repair GO:2000779 22 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
rna processing GO:0006396 255 0.014
microtubule based process GO:0007017 210 0.014
regulation of cytokine mediated signaling pathway GO:0001959 41 0.014
positive regulation of transferase activity GO:0051347 227 0.014
regulation of kinase activity GO:0043549 314 0.014
positive regulation of protein transport GO:0051222 135 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
positive regulation of innate immune response GO:0045089 79 0.013
positive regulation of defense response GO:0031349 87 0.013
metal ion transport GO:0030001 272 0.013
negative regulation of cell differentiation GO:0045596 171 0.013
positive regulation of growth GO:0045927 58 0.013
regulation of protein complex assembly GO:0043254 147 0.013
monocarboxylic acid biosynthetic process GO:0072330 67 0.013
negative regulation of gene expression epigenetic GO:0045814 19 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
cell division GO:0051301 168 0.013
Mouse
regulation of histone methylation GO:0031060 16 0.013
Mouse
negative regulation of catalytic activity GO:0043086 335 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
digestive tract morphogenesis GO:0048546 56 0.013
cell activation GO:0001775 213 0.013
response to organonitrogen compound GO:0010243 156 0.013
embryonic morphogenesis GO:0048598 85 0.012
Mouse
response to retinoic acid GO:0032526 33 0.012
blastocyst formation GO:0001825 3 0.012
demethylation GO:0070988 37 0.012
purine nucleoside triphosphate catabolic process GO:0009146 392 0.012
defense response to virus GO:0051607 71 0.012
rostrocaudal neural tube patterning GO:0021903 1 0.012
interspecies interaction between organisms GO:0044419 156 0.012
axon development GO:0061564 34 0.012
response to steroid hormone GO:0048545 80 0.012
response to estrogen GO:0043627 47 0.012
cell type specific apoptotic process GO:0097285 125 0.012
mitotic cell cycle checkpoint GO:0007093 68 0.011
regulation of homeostatic process GO:0032844 121 0.011
taxis GO:0042330 157 0.011
regulation of transporter activity GO:0032409 82 0.011
chordate embryonic development GO:0043009 34 0.011
Mouse
positive regulation of cell cycle GO:0045787 140 0.011
eye development GO:0001654 42 0.011
cellular amide metabolic process GO:0043603 69 0.011
system process GO:0003008 349 0.011
skeletal muscle tissue development GO:0007519 24 0.011
dna damage response signal transduction resulting in transcription GO:0042772 12 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.011
positive regulation of chromatin modification GO:1903310 30 0.011
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 128 0.011
regulation of intracellular transport GO:0032386 195 0.011
muscle tissue development GO:0060537 62 0.011
axis elongation GO:0003401 4 0.011
regulation of defense response to bacterium GO:1900424 2 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
cellular response to peptide hormone stimulus GO:0071375 56 0.011
defense response to fungus GO:0050832 4 0.011
establishment of tissue polarity GO:0007164 3 0.011
cellular cation homeostasis GO:0030003 163 0.011
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.010
regulation of lipid metabolic process GO:0019216 96 0.010
pattern specification process GO:0007389 43 0.010
negative regulation of protein modification process GO:0031400 200 0.010
negative regulation of chromatin silencing GO:0031936 4 0.010
mitotic dna integrity checkpoint GO:0044774 30 0.010
multicellular organismal reproductive process GO:0048609 40 0.010
Mouse
response to virus GO:0009615 126 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.010
intracellular mrna localization GO:0008298 1 0.010
positive regulation of multi organism process GO:0043902 56 0.010
regulation of dna binding GO:0051101 37 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.010
cellular macromolecule catabolic process GO:0044265 380 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.010
negative regulation of cell proliferation GO:0008285 228 0.010
regulation of nucleocytoplasmic transport GO:0046822 98 0.010

MEN1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.025
neurodegenerative disease DOID:1289 102 0.025
nervous system disease DOID:863 431 0.025
disease of metabolism DOID:0014667 295 0.023
carbohydrate metabolic disorder DOID:2978 55 0.023
inherited metabolic disorder DOID:655 242 0.023
immune system disease DOID:2914 155 0.018
congenital disorder of glycosylation DOID:5212 26 0.013
auditory system disease DOID:2742 53 0.011
sensory system disease DOID:0050155 203 0.011