Homo sapiens

77 known processes

MKL1

megakaryoblastic leukemia (translocation) 1

(Aliases: MRTF-A,BSAC,MAL)

MKL1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 1.000
Human
positive regulation of transcription via serum response element binding GO:0010735 3 0.994
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 3 0.984
Human
hematopoietic stem cell differentiation GO:0060218 4 0.678
trophectodermal cell differentiation GO:0001829 3 0.613
platelet formation GO:0030220 4 0.607
cardiac muscle cell myoblast differentiation GO:0060379 5 0.588
Human
memory GO:0007613 3 0.578
water homeostasis GO:0030104 14 0.526
associative learning GO:0008306 1 0.507
positive regulation of axon extension GO:0045773 4 0.458
patterning of blood vessels GO:0001569 2 0.435
limbic system development GO:0021761 3 0.428
long term memory GO:0007616 2 0.399
blastocyst development GO:0001824 3 0.386
smooth muscle cell differentiation GO:0051145 8 0.382
cardiac vascular smooth muscle cell differentiation GO:0060947 2 0.370
anterior posterior axis specification GO:0009948 2 0.361
sleep GO:0030431 2 0.360
blastocyst formation GO:0001825 3 0.356
regulation of synaptic plasticity GO:0048167 3 0.353
trabecula morphogenesis GO:0061383 2 0.345
platelet morphogenesis GO:0036344 4 0.342
actin filament based process GO:0030029 224 0.333
regulation of beta amyloid clearance GO:1900221 5 0.316
Human
telencephalon cell migration GO:0022029 4 0.307
post embryonic development GO:0009791 2 0.301
thymic t cell selection GO:0045061 2 0.290
negative regulation of cell migration GO:0030336 102 0.288
eyelid development in camera type eye GO:0061029 2 0.284
muscle cell cellular homeostasis GO:0046716 3 0.266
cell adhesion GO:0007155 325 0.247
negative regulation of synaptic transmission GO:0050805 2 0.245
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 3 0.241
regulation of cell adhesion GO:0030155 166 0.238
regulation of muscle cell differentiation GO:0051147 31 0.237
Human
t cell selection GO:0045058 4 0.233
regulation of anatomical structure morphogenesis GO:0022603 286 0.198
regulation of cell migration GO:0030334 289 0.198
actin cytoskeleton organization GO:0030036 207 0.196
aorta morphogenesis GO:0035909 1 0.193
muscle contraction GO:0006936 73 0.189
Human
gastrulation with mouth forming second GO:0001702 1 0.187
t cell differentiation in thymus GO:0033077 4 0.187
hippocampus development GO:0021766 1 0.187
regulation of cell motility GO:2000145 299 0.185
blood coagulation GO:0007596 76 0.185
sprouting angiogenesis GO:0002040 29 0.180
angiogenesis GO:0001525 147 0.179
nervous system development GO:0007399 293 0.176
positive regulation of cellular component biogenesis GO:0044089 158 0.175
regulation of cellular component biogenesis GO:0044087 281 0.173
positive regulation of protein complex assembly GO:0031334 86 0.163
negative regulation of cellular component movement GO:0051271 106 0.163
olfactory lobe development GO:0021988 5 0.156
regulation of muscle system process GO:0090257 53 0.155
Human
short term memory GO:0007614 1 0.153
erythrocyte development GO:0048821 3 0.152
positive thymic t cell selection GO:0045059 1 0.148
actin filament organization GO:0007015 128 0.147
positive regulation of cellular component organization GO:0051130 376 0.147
cell projection organization GO:0030030 252 0.145
olfactory bulb development GO:0021772 5 0.144
cell morphogenesis GO:0000902 296 0.143
regulation of cell growth GO:0001558 135 0.142
positive regulation of muscle contraction GO:0045933 6 0.140
Human
negative regulation of cell motility GO:2000146 104 0.138
dna templated transcription initiation GO:0006352 35 0.137
cellular component morphogenesis GO:0032989 314 0.136
endothelial cell migration GO:0043542 86 0.133
single organism cell adhesion GO:0098602 179 0.132
negative regulation of locomotion GO:0040013 118 0.131
muscle system process GO:0003012 81 0.130
Human
leukocyte activation GO:0045321 164 0.129
cell junction assembly GO:0034329 67 0.128
regulation of kinase activity GO:0043549 314 0.128
Human
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.127
regulation of cell differentiation GO:0045595 393 0.125
Human
lung morphogenesis GO:0060425 6 0.124
single organismal cell cell adhesion GO:0016337 148 0.123
cell matrix adhesion GO:0007160 85 0.120
cellular chemical homeostasis GO:0055082 180 0.120
cell development GO:0048468 328 0.120
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.119
anatomical structure formation involved in morphogenesis GO:0048646 284 0.118
smooth muscle contraction GO:0006939 14 0.117
Human
coagulation GO:0050817 78 0.116
negative regulation of cell proliferation GO:0008285 228 0.113
Human
response to cytokine GO:0034097 232 0.112
chemical homeostasis GO:0048878 306 0.108
smooth muscle tissue development GO:0048745 3 0.108
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 6 0.108
Human
regulation of water loss via skin GO:0033561 5 0.107
positive regulation of muscle cell differentiation GO:0051149 15 0.106
Human
cell aging GO:0007569 52 0.105
blood vessel endothelial cell migration GO:0043534 42 0.104
cellular senescence GO:0090398 34 0.103
carbon catabolite activation of transcription GO:0045991 3 0.100
cell migration involved in sprouting angiogenesis GO:0002042 19 0.100
regulation of locomotion GO:0040012 329 0.099
myeloid cell differentiation GO:0030099 117 0.099
vascular smooth muscle cell differentiation GO:0035886 3 0.099
regulation of cellular component movement GO:0051270 334 0.097
positive regulation of axonogenesis GO:0050772 9 0.097
anatomical structure homeostasis GO:0060249 100 0.097
cellular ketone metabolic process GO:0042180 80 0.096
neuron projection development GO:0031175 106 0.096
regulation of cell morphogenesis GO:0022604 153 0.095
tissue homeostasis GO:0001894 63 0.095
epithelium migration GO:0090132 119 0.094
positive regulation of striated muscle cell differentiation GO:0051155 9 0.092
Human
platelet activation GO:0030168 44 0.092
positive regulation of developmental process GO:0051094 314 0.091
Human
positive regulation of cell development GO:0010720 92 0.090
megakaryocyte differentiation GO:0030219 25 0.090
formation of primary germ layer GO:0001704 42 0.089
organelle assembly GO:0070925 176 0.089
cellular response to nutrient GO:0031670 12 0.089
beta amyloid clearance GO:0097242 5 0.089
Human
digestive tract morphogenesis GO:0048546 56 0.089
cardiovascular system development GO:0072358 262 0.089
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.088
cell activation GO:0001775 213 0.087
system process GO:0003008 349 0.087
Human
cell junction organization GO:0034330 79 0.086
histone modification GO:0016570 251 0.086
covalent chromatin modification GO:0016569 254 0.086
t cell activation GO:0042110 99 0.085
tissue migration GO:0090130 119 0.085
cellular homeostasis GO:0019725 196 0.085
cellular amino acid metabolic process GO:0006520 116 0.085
ameboidal type cell migration GO:0001667 135 0.084
neuron differentiation GO:0030182 138 0.083
regulation of neuron differentiation GO:0045664 70 0.082
regulation of cell projection organization GO:0031344 107 0.081
epithelial cell migration GO:0010631 119 0.080
tube morphogenesis GO:0035239 95 0.080
response to decreased oxygen levels GO:0036293 96 0.080
Human
regulation of protein complex assembly GO:0043254 147 0.078
behavior GO:0007610 112 0.077
hemopoiesis GO:0030097 180 0.077
regulation of smooth muscle contraction GO:0006940 5 0.077
Human
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.077
regulation of muscle contraction GO:0006937 45 0.077
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.075
Human
multicellular organismal homeostasis GO:0048871 67 0.074
coronary vasculature development GO:0060976 2 0.074
cardiac muscle tissue development GO:0048738 39 0.074
Human
cell substrate adhesion GO:0031589 132 0.074
regulation of cellular amino acid metabolic process GO:0006521 6 0.073
small gtpase mediated signal transduction GO:0007264 78 0.073
blood vessel morphogenesis GO:0048514 162 0.073
regulation of cell projection assembly GO:0060491 47 0.071
cellular component assembly involved in morphogenesis GO:0010927 73 0.071
regulation of cell development GO:0060284 161 0.070
immune system development GO:0002520 195 0.070
ribonucleoside triphosphate metabolic process GO:0009199 412 0.070
apical junction assembly GO:0043297 19 0.069
regulation of cellular amine metabolic process GO:0033238 11 0.068
nucleoside triphosphate metabolic process GO:0009141 422 0.067
epithelium development GO:0060429 227 0.067
trabecula formation GO:0060343 1 0.066
response to abiotic stimulus GO:0009628 336 0.066
Human
protein catabolic process GO:0030163 325 0.065
epithelial cell cell adhesion GO:0090136 7 0.065
regulation of body fluid levels GO:0050878 99 0.064
neurogenesis GO:0022008 169 0.063
regulation of cellular component size GO:0032535 82 0.063
cell projection assembly GO:0030031 126 0.063
growth GO:0040007 202 0.062
response to hormone GO:0009725 175 0.062
cell cell junction assembly GO:0007043 25 0.062
multicellular organismal water homeostasis GO:0050891 14 0.062
regulation of axonogenesis GO:0050770 16 0.062
positive regulation of cell differentiation GO:0045597 211 0.062
Human
regulation of neuron projection development GO:0010975 57 0.062
pallium development GO:0021543 10 0.061
regulation of transcription by glucose GO:0046015 4 0.061
myoblast differentiation GO:0045445 21 0.061
Human
generation of neurons GO:0048699 152 0.061
positive regulation of neurogenesis GO:0050769 49 0.061
developmental cell growth GO:0048588 18 0.060
post embryonic organ development GO:0048569 1 0.060
cellular response to nutrient levels GO:0031669 69 0.059
female gamete generation GO:0007292 2 0.058
morphogenesis of a branching structure GO:0001763 21 0.058
blood vessel development GO:0001568 172 0.058
positive regulation of cell projection organization GO:0031346 64 0.058
cellular response to oxygen containing compound GO:1901701 276 0.057
regulation of nervous system development GO:0051960 88 0.057
negative regulation of phosphorus metabolic process GO:0010563 267 0.056
Human
trachea development GO:0060438 1 0.056
purine containing compound catabolic process GO:0072523 411 0.056
vesicle mediated transport GO:0016192 371 0.056
neuron development GO:0048666 113 0.056
positive t cell selection GO:0043368 2 0.055
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.055
mesoderm morphogenesis GO:0048332 11 0.055
purine ribonucleotide catabolic process GO:0009154 404 0.054
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003256 3 0.054
Human
nucleoside catabolic process GO:0009164 408 0.054
purine nucleoside triphosphate catabolic process GO:0009146 392 0.054
skin development GO:0043588 76 0.054
oogenesis GO:0048477 2 0.054
response to hypoxia GO:0001666 96 0.053
Human
actin filament bundle organization GO:0061572 54 0.053
leukocyte differentiation GO:0002521 98 0.053
stress fiber assembly GO:0043149 40 0.053
negative regulation of protein modification process GO:0031400 200 0.053
Human
mrna transcription from rna polymerase ii promoter GO:0042789 6 0.052
ras protein signal transduction GO:0007265 73 0.052
positive regulation of cell growth GO:0030307 48 0.052
gastrulation GO:0007369 51 0.052
hematopoietic progenitor cell differentiation GO:0002244 38 0.051
regulation of muscle organ development GO:0048634 27 0.051
Human
glycosyl compound catabolic process GO:1901658 413 0.051
regulation of cell cycle GO:0051726 393 0.051
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.051
negative regulation of multicellular organismal process GO:0051241 317 0.050
Human
brain development GO:0007420 97 0.050
chromatin organization GO:0006325 351 0.050
actin filament bundle assembly GO:0051017 54 0.049
telencephalon development GO:0021537 17 0.049
cardiac myofibril assembly GO:0055003 3 0.049
myeloid cell development GO:0061515 5 0.049
regulation of anatomical structure size GO:0090066 101 0.049
purine ribonucleoside catabolic process GO:0046130 398 0.049
aorta development GO:0035904 2 0.049
neurological system process GO:0050877 163 0.049
ribonucleoside catabolic process GO:0042454 406 0.049
vasculature development GO:0001944 181 0.048
biological adhesion GO:0022610 331 0.048
cardiac chamber morphogenesis GO:0003206 26 0.048
cell morphogenesis involved in differentiation GO:0000904 144 0.048
negative regulation of phosphate metabolic process GO:0045936 267 0.048
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.048
ribonucleotide catabolic process GO:0009261 405 0.047
nucleoside phosphate catabolic process GO:1901292 412 0.047
mesoderm development GO:0007498 14 0.047
determination of bilateral symmetry GO:0009855 15 0.047
branching morphogenesis of an epithelial tube GO:0048754 19 0.046
positive regulation of neuron differentiation GO:0045666 40 0.046
organophosphate catabolic process GO:0046434 430 0.046
heart trabecula morphogenesis GO:0061384 1 0.046
positive regulation of muscle organ development GO:0048636 7 0.046
Human
cell cell signaling GO:0007267 155 0.045
somatic muscle development GO:0007525 1 0.045
nucleoside triphosphate catabolic process GO:0009143 394 0.045
regulation of transferase activity GO:0051338 355 0.045
Human
embryonic morphogenesis GO:0048598 85 0.045
erythrocyte differentiation GO:0030218 28 0.045
central nervous system development GO:0007417 123 0.045
positive regulation of nucleoside metabolic process GO:0045979 186 0.044
head development GO:0060322 108 0.044
response to oxygen containing compound GO:1901700 369 0.044
connective tissue development GO:0061448 39 0.044
gtp catabolic process GO:0006184 237 0.044
internal protein amino acid acetylation GO:0006475 101 0.043
rho protein signal transduction GO:0007266 26 0.043
purine ribonucleoside metabolic process GO:0046128 437 0.043
cell part morphogenesis GO:0032990 137 0.043
regulation of protein serine threonine kinase activity GO:0071900 179 0.043
Human
homeostasis of number of cells GO:0048872 40 0.043
positive regulation of nervous system development GO:0051962 54 0.042
morphogenesis of an epithelium GO:0002009 60 0.042
nucleotide catabolic process GO:0009166 408 0.042
regulation of striated muscle tissue development GO:0016202 26 0.042
Human
cellular response to carbohydrate stimulus GO:0071322 11 0.042
skeletal system development GO:0001501 79 0.042
myoblast fusion GO:0007520 1 0.042
positive regulation of cellular amine metabolic process GO:0033240 7 0.042
locomotory behavior GO:0007626 1 0.042
purine nucleoside triphosphate metabolic process GO:0009144 412 0.041
purine nucleotide catabolic process GO:0006195 405 0.041
digestive tract development GO:0048565 75 0.041
guanosine containing compound catabolic process GO:1901069 239 0.041
determination of left right symmetry GO:0007368 11 0.041
regulation of smooth muscle cell differentiation GO:0051150 3 0.041
Human
organ morphogenesis GO:0009887 147 0.040
erythrocyte homeostasis GO:0034101 31 0.040
tissue morphogenesis GO:0048729 96 0.040
circulatory system development GO:0072359 262 0.040
Human
gtp metabolic process GO:0046039 239 0.040
signal transduction by phosphorylation GO:0023014 297 0.040
morphogenesis of an epithelial sheet GO:0002011 12 0.040
amine metabolic process GO:0009308 44 0.039
cellular response to endogenous stimulus GO:0071495 336 0.039
regulation of gtpase activity GO:0043087 180 0.039
positive regulation of hydrolase activity GO:0051345 331 0.039
multicellular organismal aging GO:0010259 3 0.039
response to wounding GO:0009611 168 0.039
wound healing GO:0042060 115 0.039
negative regulation of striated muscle tissue development GO:0045843 11 0.038
Human
negative regulation of cell death GO:0060548 345 0.038
Mouse
morphogenesis of a branching epithelium GO:0061138 20 0.038
digestive system development GO:0055123 75 0.038
positive regulation of protein phosphorylation GO:0001934 313 0.038
ribonucleoside triphosphate catabolic process GO:0009203 391 0.038
synaptic transmission GO:0007268 61 0.038
epithelial structure maintenance GO:0010669 9 0.038
positive regulation of catabolic process GO:0009896 310 0.038
myeloid cell homeostasis GO:0002262 34 0.037
protein acetylation GO:0006473 116 0.037
response to hexose GO:0009746 20 0.037
enzyme linked receptor protein signaling pathway GO:0007167 303 0.037
axon extension GO:0048675 13 0.037
positive regulation of neuron projection development GO:0010976 34 0.037
tube development GO:0035295 125 0.036
determination of adult lifespan GO:0008340 2 0.036
purine nucleoside catabolic process GO:0006152 398 0.036
negative regulation of cell cycle GO:0045786 193 0.036
Human
actomyosin structure organization GO:0031032 59 0.036
mrna transcription GO:0009299 8 0.036
negative regulation of cell differentiation GO:0045596 171 0.035
Human
histone acetylation GO:0016573 93 0.035
embryonic organ morphogenesis GO:0048562 24 0.035
regulation of gtp catabolic process GO:0033124 180 0.035
regulation of purine nucleotide metabolic process GO:1900542 264 0.035
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
Human Mouse
negative regulation of protein metabolic process GO:0051248 391 0.035
Human Mouse
regulation of cardiac muscle tissue development GO:0055024 13 0.034
Human
regulation of nucleotide catabolic process GO:0030811 205 0.034
cellular response to external stimulus GO:0071496 111 0.034
neuron projection extension GO:1990138 14 0.034
heart development GO:0007507 95 0.034
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
regulation of purine nucleotide catabolic process GO:0033121 205 0.033
positive regulation of cellular catabolic process GO:0031331 284 0.033
striated muscle adaptation GO:0014888 4 0.033
regulation of system process GO:0044057 101 0.033
Human
negative regulation of phosphorylation GO:0042326 174 0.033
Human
peptidyl lysine modification GO:0018205 144 0.033
regulation of nucleotide metabolic process GO:0006140 269 0.032
epithelial tube morphogenesis GO:0060562 38 0.032
neuromuscular junction development GO:0007528 3 0.032
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.031
regulation of response to external stimulus GO:0032101 222 0.031
guanosine containing compound metabolic process GO:1901068 244 0.031
positive regulation of gtpase activity GO:0043547 166 0.030
forebrain development GO:0030900 26 0.030
cellular amine metabolic process GO:0044106 41 0.030
striated muscle cell differentiation GO:0051146 43 0.030
Human
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.030
Human
regeneration GO:0031099 4 0.030
regulation of nucleoside metabolic process GO:0009118 209 0.030
t cell differentiation GO:0030217 29 0.030
neuron projection morphogenesis GO:0048812 50 0.030
regulation of mapk cascade GO:0043408 262 0.030
cardiac muscle cell differentiation GO:0055007 15 0.029
Human
regulation of dna templated transcription initiation GO:2000142 9 0.029
developmental growth GO:0048589 48 0.028
regulation of growth GO:0040008 165 0.028
oocyte differentiation GO:0009994 2 0.028
cartilage development GO:0051216 31 0.028
rna processing GO:0006396 255 0.028
response to other organism GO:0051707 261 0.028
cell fate determination GO:0001709 3 0.027
muscle cell differentiation GO:0042692 63 0.027
positive regulation of gtp catabolic process GO:0033126 166 0.027
cell projection morphogenesis GO:0048858 129 0.027
positive regulation of phosphorylation GO:0042327 394 0.027
regulation of cardiac muscle cell differentiation GO:2000725 7 0.027
Human
cellular response to monosaccharide stimulus GO:0071326 10 0.027
regulation of cellular response to stress GO:0080135 244 0.026
oocyte development GO:0048599 1 0.026
segmentation GO:0035282 4 0.026
peptidyl lysine acetylation GO:0018394 101 0.026
regulation of myoblast fusion GO:1901739 1 0.026
positive regulation of growth GO:0045927 58 0.026
cellular response to extracellular stimulus GO:0031668 72 0.026
positive regulation of nucleotide catabolic process GO:0030813 185 0.026
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.025
negative regulation of kinase activity GO:0033673 106 0.025
Human
response to glucose GO:0009749 19 0.025
positive regulation of nucleotide metabolic process GO:0045981 230 0.025
cellular response to hexose stimulus GO:0071331 10 0.025
regulation of cell cycle process GO:0010564 266 0.025
positive regulation of cell proliferation GO:0008284 301 0.025
cell growth GO:0016049 160 0.025
response to monosaccharide GO:0034284 20 0.025
heart morphogenesis GO:0003007 48 0.024
embryo development GO:0009790 123 0.024
regulation of small gtpase mediated signal transduction GO:0051056 156 0.024
regulation of ras protein signal transduction GO:0046578 155 0.023
membrane organization GO:0061024 292 0.023
rna splicing GO:0008380 131 0.023
response to nutrient GO:0007584 20 0.023
morphogenesis of embryonic epithelium GO:0016331 4 0.023
striated muscle tissue development GO:0014706 59 0.023
Human
carbohydrate homeostasis GO:0033500 31 0.023
cellular glucose homeostasis GO:0001678 11 0.022
negative regulation of protein kinase activity GO:0006469 98 0.022
Human
response to carbohydrate GO:0009743 21 0.022
single organism membrane organization GO:0044802 268 0.022
skin morphogenesis GO:0043589 6 0.022
mitotic cell cycle GO:0000278 326 0.022
response to extracellular stimulus GO:0009991 85 0.022
dephosphorylation GO:0016311 209 0.022
endocytosis GO:0006897 159 0.022
mapk cascade GO:0000165 288 0.022
positive regulation of kinase activity GO:0033674 204 0.022
cytoplasmic transport GO:0016482 379 0.022
microtubule based process GO:0007017 210 0.021
response to external biotic stimulus GO:0043207 261 0.021
protein autophosphorylation GO:0046777 123 0.021
blastoderm segmentation GO:0007350 2 0.021
response to oxygen levels GO:0070482 100 0.021
Human
protein localization to organelle GO:0033365 280 0.021
response to growth factor GO:0070848 205 0.021
regulation of filopodium assembly GO:0051489 13 0.021
cellular response to glucose stimulus GO:0071333 10 0.021
ion transmembrane transport GO:0034220 338 0.021
adult locomotory behavior GO:0008344 1 0.021
single organism carbohydrate metabolic process GO:0044723 193 0.021
transmembrane transport GO:0055085 399 0.021
tight junction assembly GO:0070830 14 0.020
pattern specification process GO:0007389 43 0.020
regulation of ras gtpase activity GO:0032318 128 0.020
protein ubiquitination GO:0016567 314 0.020
compound eye development GO:0048749 1 0.020
microtubule cytoskeleton organization GO:0000226 176 0.020
immune response GO:0006955 307 0.020
negative regulation of skeletal muscle tissue development GO:0048642 2 0.020
Human
positive regulation of immune system process GO:0002684 283 0.020
positive regulation of transferase activity GO:0051347 227 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
Human Mouse
tripartite regional subdivision GO:0007351 2 0.020
regionalization GO:0003002 29 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.019
spermatid differentiation GO:0048515 4 0.019
positive regulation of cell cycle process GO:0090068 106 0.019
muscle structure development GO:0061061 98 0.019
regulation of vesicle mediated transport GO:0060627 130 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
Mouse
anterior posterior axis specification embryo GO:0008595 2 0.019
neuroblast proliferation GO:0007405 4 0.019
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.019
cellular protein complex assembly GO:0043623 188 0.019
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
positive regulation of apoptotic process GO:0043065 246 0.019
cation transport GO:0006812 331 0.019
regulation of protein localization GO:0032880 296 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
regulation of cellular ketone metabolic process GO:0010565 50 0.019
artery morphogenesis GO:0048844 7 0.019
peptidyl tyrosine modification GO:0018212 170 0.019
mitotic cell cycle process GO:1903047 286 0.018
ion homeostasis GO:0050801 230 0.018
positive regulation of locomotion GO:0040017 186 0.018
regulation of cytoskeleton organization GO:0051493 177 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
determination of heart left right asymmetry GO:0061371 8 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
Mouse
muscle cell development GO:0055001 29 0.018
negative regulation of transferase activity GO:0051348 124 0.018
Human
muscle tissue development GO:0060537 62 0.018
Human
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
embryonic organ development GO:0048568 36 0.018
negative regulation of muscle tissue development GO:1901862 11 0.018
Human
specification of symmetry GO:0009799 16 0.018
organonitrogen compound biosynthetic process GO:1901566 200 0.018
intracellular protein transport GO:0006886 270 0.018
single organism cellular localization GO:1902580 332 0.018
sarcomere organization GO:0045214 8 0.018
cellular macromolecule catabolic process GO:0044265 380 0.018
cognition GO:0050890 43 0.018
stem cell division GO:0017145 2 0.017
inorganic ion transmembrane transport GO:0098660 231 0.017
lipid metabolic process GO:0006629 381 0.017
chordate embryonic development GO:0043009 34 0.017
positive regulation of transport GO:0051050 336 0.017
respiratory system development GO:0060541 22 0.017
carbohydrate metabolic process GO:0005975 207 0.017
metal ion transport GO:0030001 272 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.017
negative regulation of transport GO:0051051 176 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
spermatid development GO:0007286 4 0.017
respiratory tube development GO:0030323 20 0.017
response to fungus GO:0009620 4 0.017
hindbrain development GO:0030902 3 0.017
nucleocytoplasmic transport GO:0006913 176 0.017
peptidyl tyrosine phosphorylation GO:0018108 170 0.017
negative regulation of developmental process GO:0051093 247 0.017
Human
regulation of axon extension GO:0030516 7 0.016

MKL1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.026
disease of cellular proliferation DOID:14566 174 0.024
cancer DOID:162 167 0.024
organ system cancer DOID:0050686 164 0.022
sensory system disease DOID:0050155 203 0.022
nervous system disease DOID:863 431 0.022
central nervous system disease DOID:331 186 0.018
musculoskeletal system disease DOID:17 223 0.018
immune system disease DOID:2914 155 0.017