Homo sapiens

91 known processes

MKL2

MKL/myocardin-like 2

(Aliases: MRTF-B,DKFZp686J1745,FLJ45623,FLJ31823,NPD001)

MKL2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.999
Human
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003256 3 0.857
Human
positive regulation of transcription via serum response element binding GO:0010735 3 0.422
Human
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 3 0.367
Human
post embryonic development GO:0009791 2 0.223
regulation of muscle system process GO:0090257 53 0.162
Human
regulation of cellular amine metabolic process GO:0033238 11 0.155
positive regulation of axon extension GO:0045773 4 0.122
neuromuscular junction development GO:0007528 3 0.121
regulation of cell cycle GO:0051726 393 0.120
Human
regulation of cellular component biogenesis GO:0044087 281 0.118
positive regulation of cellular component organization GO:0051130 376 0.114
memory GO:0007613 3 0.112
blood vessel endothelial cell migration GO:0043534 42 0.109
protein catabolic process GO:0030163 325 0.102
mesodermal cell fate commitment GO:0001710 2 0.100
associative learning GO:0008306 1 0.097
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 2 0.096
negative regulation of apoptotic process GO:0043066 316 0.094
positive regulation of cell differentiation GO:0045597 211 0.093
Human
regulation of synaptic plasticity GO:0048167 3 0.090
regulation of cellular ketone metabolic process GO:0010565 50 0.089
limbic system development GO:0021761 3 0.089
negative regulation of phosphate metabolic process GO:0045936 267 0.086
Human
cellular amino acid metabolic process GO:0006520 116 0.085
cellular ketone metabolic process GO:0042180 80 0.084
anatomical structure formation involved in morphogenesis GO:0048646 284 0.083
cell substrate adhesion GO:0031589 132 0.083
regulation of cellular amino acid metabolic process GO:0006521 6 0.079
muscle contraction GO:0006936 73 0.079
Human
amine metabolic process GO:0009308 44 0.078
positive regulation of transport GO:0051050 336 0.078
biological adhesion GO:0022610 331 0.077
sleep GO:0030431 2 0.077
negative regulation of cell death GO:0060548 345 0.077
long term memory GO:0007616 2 0.077
gastrulation GO:0007369 51 0.076
patterning of blood vessels GO:0001569 2 0.075
negative regulation of phosphorus metabolic process GO:0010563 267 0.075
Human
retinal ganglion cell axon guidance GO:0031290 2 0.074
chemical homeostasis GO:0048878 306 0.073
positive regulation of smooth muscle contraction GO:0045987 5 0.072
Human
regulation of cell morphogenesis GO:0022604 153 0.071
gastrulation with mouth forming second GO:0001702 1 0.070
regulation of cell growth GO:0001558 135 0.069
trophectodermal cell differentiation GO:0001829 3 0.069
anterior posterior axis specification GO:0009948 2 0.068
actin filament based process GO:0030029 224 0.066
regulation of cell differentiation GO:0045595 393 0.066
Human
evasion or tolerance of host defenses by virus GO:0019049 2 0.065
cellular response to endogenous stimulus GO:0071495 336 0.064
cell adhesion GO:0007155 325 0.063
platelet formation GO:0030220 4 0.063
negative regulation of cell proliferation GO:0008285 228 0.062
Human
t cell selection GO:0045058 4 0.062
negative regulation of pathway restricted smad protein phosphorylation GO:0060394 11 0.062
regulation of proteolysis GO:0030162 293 0.060
cell morphogenesis GO:0000902 296 0.059
cell projection organization GO:0030030 252 0.059
negative regulation of programmed cell death GO:0043069 321 0.059
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.058
endothelial cell migration GO:0043542 86 0.058
muscle cell cellular homeostasis GO:0046716 3 0.058
regulation of cellular component movement GO:0051270 334 0.058
regulation of establishment of protein localization GO:0070201 242 0.057
regulation of meiotic cell cycle GO:0051445 4 0.057
generation of neurons GO:0048699 152 0.057
system process GO:0003008 349 0.056
Human
segmentation GO:0035282 4 0.056
t cell differentiation in thymus GO:0033077 4 0.056
cell junction organization GO:0034330 79 0.056
regulation of protein complex assembly GO:0043254 147 0.055
cellular component morphogenesis GO:0032989 314 0.055
single organism cell adhesion GO:0098602 179 0.055
negative regulation of synaptic transmission GO:0050805 2 0.055
oogenesis GO:0048477 2 0.055
blastoderm segmentation GO:0007350 2 0.054
negative regulation of protein modification process GO:0031400 200 0.053
Human
negative regulation of cellular amine metabolic process GO:0033239 3 0.053
regulation of cell motility GO:2000145 299 0.053
positive regulation of cellular catabolic process GO:0031331 284 0.053
regulation of pathway restricted smad protein phosphorylation GO:0060393 34 0.053
single organismal cell cell adhesion GO:0016337 148 0.053
negative regulation of transferase activity GO:0051348 124 0.052
Human
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.052
response to abiotic stimulus GO:0009628 336 0.052
Human
protein targeting GO:0006605 187 0.052
hippocampus development GO:0021766 1 0.052
regulation of mapk cascade GO:0043408 262 0.051
female gamete generation GO:0007292 2 0.051
actin cytoskeleton organization GO:0030036 207 0.051
regulation of cell adhesion GO:0030155 166 0.051
regulation of cell migration GO:0030334 289 0.050
vasculature development GO:0001944 181 0.049
Mouse
regulation of locomotion GO:0040012 329 0.049
regulation of anatomical structure morphogenesis GO:0022603 286 0.048
response to growth factor GO:0070848 205 0.048
regulation of protein localization GO:0032880 296 0.048
cellular macromolecule catabolic process GO:0044265 380 0.047
cellular amine metabolic process GO:0044106 41 0.047
positive regulation of developmental process GO:0051094 314 0.046
intracellular protein transport GO:0006886 270 0.046
growth GO:0040007 202 0.045
blastocyst formation GO:0001825 3 0.045
positive regulation of catabolic process GO:0009896 310 0.045
regulation of kinase activity GO:0043549 314 0.045
Human
cytoplasmic transport GO:0016482 379 0.045
immune response GO:0006955 307 0.045
negative regulation of protein metabolic process GO:0051248 391 0.044
Human
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.044
vesicle mediated transport GO:0016192 371 0.044
actin filament organization GO:0007015 128 0.043
cell growth GO:0016049 160 0.043
response to oxygen containing compound GO:1901700 369 0.043
cellular protein catabolic process GO:0044257 261 0.043
hematopoietic stem cell differentiation GO:0060218 4 0.042
regulation of transferase activity GO:0051338 355 0.042
Human
protein localization to organelle GO:0033365 280 0.041
cardiac vascular smooth muscle cell differentiation GO:0060947 2 0.041
tube morphogenesis GO:0035239 95 0.041
response to decreased oxygen levels GO:0036293 96 0.041
Human
nervous system development GO:0007399 293 0.041
single organism cellular localization GO:1902580 332 0.041
endodermal cell fate commitment GO:0001711 4 0.040
eyelid development in camera type eye GO:0061029 2 0.040
somatic stem cell maintenance GO:0035019 4 0.040
short term memory GO:0007614 1 0.040
formation of primary germ layer GO:0001704 42 0.040
negative regulation of sodium ion transmembrane transporter activity GO:2000650 2 0.040
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.039
cell cell junction organization GO:0045216 69 0.039
cellular macromolecular complex assembly GO:0034622 324 0.039
endodermal cell fate specification GO:0001714 4 0.039
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.039
Human
tissue migration GO:0090130 119 0.039
sex determination GO:0007530 3 0.039
negative regulation of cellular protein metabolic process GO:0032269 353 0.039
Human
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.039
cell projection assembly GO:0030031 126 0.038
nucleotide catabolic process GO:0009166 408 0.038
neurological system process GO:0050877 163 0.038
protein modification by small protein conjugation GO:0032446 342 0.038
enzyme linked receptor protein signaling pathway GO:0007167 303 0.038
ubiquitin dependent protein catabolic process GO:0006511 206 0.038
cell part morphogenesis GO:0032990 137 0.038
viral process GO:0016032 146 0.038
mitotic cell cycle GO:0000278 326 0.038
positive regulation of hydrolase activity GO:0051345 331 0.038
wnt signaling pathway GO:0016055 156 0.037
circulatory system development GO:0072359 262 0.037
Human Mouse
regulation of cellular component size GO:0032535 82 0.037
purine nucleoside triphosphate catabolic process GO:0009146 392 0.037
regulation of muscle contraction GO:0006937 45 0.037
Human
response to external biotic stimulus GO:0043207 261 0.037
regulation of cell development GO:0060284 161 0.036
nucleoside triphosphate catabolic process GO:0009143 394 0.036
regulation of intracellular transport GO:0032386 195 0.036
cellular chemical homeostasis GO:0055082 180 0.036
negative regulation of catalytic activity GO:0043086 335 0.036
Human
cell morphogenesis involved in differentiation GO:0000904 144 0.036
regulation of protein transport GO:0051223 213 0.036
protein processing GO:0016485 226 0.035
positive regulation of cellular amine metabolic process GO:0033240 7 0.035
protein ubiquitination GO:0016567 314 0.035
negative regulation of cell cycle GO:0045786 193 0.035
Human
positive regulation of cellular component biogenesis GO:0044089 158 0.035
smad protein complex assembly GO:0007183 12 0.035
multi organism cellular process GO:0044764 156 0.035
apoptotic signaling pathway GO:0097190 268 0.035
regulation of growth GO:0040008 165 0.035
negative regulation of locomotion GO:0040013 118 0.035
response to other organism GO:0051707 261 0.035
morphogenesis of embryonic epithelium GO:0016331 4 0.034
posttranscriptional regulation of gene expression GO:0010608 213 0.034
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.034
intraciliary transport GO:0042073 7 0.034
positive regulation of phosphorylation GO:0042327 394 0.034
organelle assembly GO:0070925 176 0.034
cell junction assembly GO:0034329 67 0.034
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 3 0.034
regulation of smooth muscle cell differentiation GO:0051150 3 0.034
Human
proteasomal protein catabolic process GO:0010498 176 0.033
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.033
cellular lipid metabolic process GO:0044255 303 0.033
anatomical structure homeostasis GO:0060249 100 0.033
stem cell division GO:0017145 2 0.033
regulation of anatomical structure size GO:0090066 101 0.033
positive regulation of protein catabolic process GO:0045732 75 0.033
hindbrain development GO:0030902 3 0.033
cardiovascular system development GO:0072358 262 0.033
Human Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.032
positive regulation of protein phosphorylation GO:0001934 313 0.032
neurogenesis GO:0022008 169 0.032
response to cytokine GO:0034097 232 0.032
response to host GO:0075136 2 0.032
regulation of cell projection organization GO:0031344 107 0.032
modification dependent protein catabolic process GO:0019941 209 0.032
erythrocyte development GO:0048821 3 0.032
digestive system development GO:0055123 75 0.032
cation transport GO:0006812 331 0.031
cofactor metabolic process GO:0051186 87 0.031
trabecula morphogenesis GO:0061383 2 0.031
regulation of protein kinase activity GO:0045859 289 0.031
Human
stem cell differentiation GO:0048863 93 0.031
Human
cell cell signaling GO:0007267 155 0.031
aorta morphogenesis GO:0035909 1 0.030
determination of adult lifespan GO:0008340 2 0.030
cell activation GO:0001775 213 0.030
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.030
cellular homeostasis GO:0019725 196 0.030
t cell activation GO:0042110 99 0.030
evasion or tolerance of host defenses GO:0044415 2 0.030
ribonucleoside catabolic process GO:0042454 406 0.030
response to wounding GO:0009611 168 0.029
rna processing GO:0006396 255 0.029
positive regulation of cell projection organization GO:0031346 64 0.029
regulation of protein catabolic process GO:0042176 155 0.029
negative regulation of cell motility GO:2000146 104 0.029
defense response GO:0006952 315 0.029
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.028
response to oxygen levels GO:0070482 100 0.028
Human
small molecule biosynthetic process GO:0044283 157 0.028
ras protein signal transduction GO:0007265 73 0.028
regulation of peptidase activity GO:0052547 180 0.028
cell development GO:0048468 328 0.028
ion transmembrane transport GO:0034220 338 0.028
purine ribonucleoside metabolic process GO:0046128 437 0.028
response to host defenses GO:0052200 2 0.028
negative regulation of cell differentiation GO:0045596 171 0.028
Human
protein maturation GO:0051604 233 0.027
neuron differentiation GO:0030182 138 0.027
cilium morphogenesis GO:0060271 75 0.027
neuron projection development GO:0031175 106 0.027
monocarboxylic acid metabolic process GO:0032787 185 0.027
cellular component assembly involved in morphogenesis GO:0010927 73 0.027
mapk cascade GO:0000165 288 0.027
extrinsic apoptotic signaling pathway GO:0097191 119 0.027
determination of bilateral symmetry GO:0009855 15 0.027
negative regulation of cell migration GO:0030336 102 0.027
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.027
regulation of activin receptor signaling pathway GO:0032925 14 0.027
blastocyst development GO:0001824 3 0.027
ribonucleoside triphosphate metabolic process GO:0009199 412 0.027
regulation of mesoderm development GO:2000380 4 0.027
regulation of cell cycle process GO:0010564 266 0.027
nucleocytoplasmic transport GO:0006913 176 0.027
pathway restricted smad protein phosphorylation GO:0060389 38 0.027
regulation of endopeptidase activity GO:0052548 170 0.027
response to biotic stimulus GO:0009607 276 0.026
purine nucleotide catabolic process GO:0006195 405 0.026
embryonic morphogenesis GO:0048598 85 0.026
heart morphogenesis GO:0003007 48 0.026
Mouse
cellular protein complex assembly GO:0043623 188 0.026
regulation of cytoplasmic transport GO:1903649 149 0.026
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 4 0.026
chromatin organization GO:0006325 351 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
digestive tract development GO:0048565 75 0.025
fatty acid metabolic process GO:0006631 115 0.025
response to hypoxia GO:0001666 96 0.025
Human
tissue homeostasis GO:0001894 63 0.025
transmembrane transport GO:0055085 399 0.025
positive regulation of cell development GO:0010720 92 0.025
platelet morphogenesis GO:0036344 4 0.025
blood vessel development GO:0001568 172 0.025
Mouse
metal ion transport GO:0030001 272 0.025
positive regulation of proteolysis GO:0045862 142 0.025
establishment of protein localization to organelle GO:0072594 172 0.025
nitrogen compound transport GO:0071705 191 0.025
regulation of cysteine type endopeptidase activity GO:2000116 127 0.025
purine nucleoside triphosphate metabolic process GO:0009144 412 0.025
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.025
positive thymic t cell selection GO:0045059 1 0.025
epithelium development GO:0060429 227 0.024
carbon catabolite activation of transcription GO:0045991 3 0.024
trachea development GO:0060438 1 0.024
cellular response to growth factor stimulus GO:0071363 197 0.024
regulation of system process GO:0044057 101 0.024
Human
regulation of response to external stimulus GO:0032101 222 0.024
rho protein signal transduction GO:0007266 26 0.024
modification dependent macromolecule catabolic process GO:0043632 212 0.024
ribonucleotide catabolic process GO:0009261 405 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
cardiac muscle tissue development GO:0048738 39 0.024
Human Mouse
regulation of isoprenoid metabolic process GO:0019747 1 0.024
regulation of body fluid levels GO:0050878 99 0.024
potassium ion transport GO:0006813 62 0.024
specification of symmetry GO:0009799 16 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.024
interspecies interaction between organisms GO:0044419 156 0.024
multicellular organismal aging GO:0010259 3 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.024
positive regulation of wnt signaling pathway GO:0030177 54 0.023
myoblast differentiation GO:0045445 21 0.023
Human
regulation of cellular protein catabolic process GO:1903362 96 0.023
regulation of mitotic cell cycle GO:0007346 189 0.023
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.023
regulation of nervous system development GO:0051960 88 0.023
brain development GO:0007420 97 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.023
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.023
organophosphate catabolic process GO:0046434 430 0.023
nucleoside catabolic process GO:0009164 408 0.023
epithelial tube morphogenesis GO:0060562 38 0.023
regulation of transcription from rna polymerase ii promoter mitotic GO:0046021 1 0.023
regeneration GO:0031099 4 0.023
negative regulation of cellular component movement GO:0051271 106 0.023
dephosphorylation GO:0016311 209 0.023
histone modification GO:0016570 251 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
common partner smad protein phosphorylation GO:0007182 3 0.022
angiogenesis GO:0001525 147 0.022
skeletal system development GO:0001501 79 0.022
coenzyme metabolic process GO:0006732 65 0.022
lateral mesoderm development GO:0048368 1 0.022
glycosyl compound catabolic process GO:1901658 413 0.022
regulation of stem cell differentiation GO:2000736 56 0.022
head development GO:0060322 108 0.022
regulation of protein serine threonine kinase activity GO:0071900 179 0.022
Human
cell fate determination GO:0001709 3 0.022
response to hormone GO:0009725 175 0.022
positive regulation of protein transport GO:0051222 135 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
hematopoietic or lymphoid organ development GO:0048534 186 0.022
positive regulation of cytoplasmic transport GO:1903651 82 0.022
regulation of striated muscle tissue development GO:0016202 26 0.022
regulation of actin filament based process GO:0032970 141 0.021
cell matrix adhesion GO:0007160 85 0.021
muscle system process GO:0003012 81 0.021
Human
ion homeostasis GO:0050801 230 0.021
actin filament bundle assembly GO:0051017 54 0.021
nuclear transport GO:0051169 179 0.021
locomotory behavior GO:0007626 1 0.021
canonical wnt signaling pathway GO:0060070 116 0.021
purine nucleoside catabolic process GO:0006152 398 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
cardiac chamber development GO:0003205 30 0.021
cardiac muscle cell myoblast differentiation GO:0060379 5 0.021
Human
positive regulation of programmed cell death GO:0043068 249 0.021
multicellular organismal homeostasis GO:0048871 67 0.021
regulation of protein targeting GO:1903533 91 0.021
regulation of protein ubiquitination GO:0031396 95 0.021
positive regulation of transcription from rna polymerase ii promoter during mitosis GO:0046022 1 0.021
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.021
coagulation GO:0050817 78 0.021
avoidance of defenses of other organism involved in symbiotic interaction GO:0051832 2 0.021
signal transduction by phosphorylation GO:0023014 297 0.021
regulation of multi organism process GO:0043900 157 0.021
cellular response to oxygen containing compound GO:1901701 276 0.021
transforming growth factor beta production GO:0071604 14 0.021
avoidance of host defenses GO:0044413 2 0.021
monovalent inorganic cation transport GO:0015672 128 0.020
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.020
regulation of ion transmembrane transport GO:0034765 132 0.020
positive regulation of intracellular protein transport GO:0090316 76 0.020
positive regulation of organ growth GO:0046622 2 0.020
regulation of nucleotide metabolic process GO:0006140 269 0.020
leukocyte activation GO:0045321 164 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
negative regulation of catabolic process GO:0009895 104 0.020
positive regulation of mesoderm development GO:2000382 2 0.020
interaction with host GO:0051701 42 0.020
thymic t cell selection GO:0045061 2 0.020
immune system development GO:0002520 195 0.020
leukocyte differentiation GO:0002521 98 0.020
regulation of potassium ion transmembrane transporter activity GO:1901016 16 0.020
positive regulation of transcription during mitosis GO:0045897 2 0.020
late endosome to vacuole transport GO:0045324 2 0.020
digestive tract morphogenesis GO:0048546 56 0.020
peptidyl serine modification GO:0018209 106 0.020
sprouting angiogenesis GO:0002040 29 0.019
myoblast fusion GO:0007520 1 0.019
smooth muscle cell differentiation GO:0051145 8 0.019
Human Mouse
positive regulation of growth GO:0045927 58 0.019
regulation of neuron projection development GO:0010975 57 0.019
positive regulation of epithelial to mesenchymal transition GO:0010718 22 0.019
vascular smooth muscle cell differentiation GO:0035886 3 0.019
mitotic cell cycle phase transition GO:0044772 162 0.019
mitotic cell cycle process GO:1903047 286 0.019
somatic muscle development GO:0007525 1 0.019
microtubule based process GO:0007017 210 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
myeloid cell homeostasis GO:0002262 34 0.019
atrioventricular valve development GO:0003171 3 0.019
stress fiber assembly GO:0043149 40 0.019
regulation of cytokine production GO:0001817 232 0.019
regulation of epithelial cell migration GO:0010632 93 0.019
regulation of intracellular protein transport GO:0033157 123 0.019
cilium organization GO:0044782 68 0.019
positive regulation of intracellular transport GO:0032388 104 0.019
oocyte development GO:0048599 1 0.019
cardiac chamber morphogenesis GO:0003206 26 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.019
sodium ion transmembrane transport GO:0035725 59 0.019
organ formation GO:0048645 3 0.019
tissue regeneration GO:0042246 3 0.019
fatty acid biosynthetic process GO:0006633 46 0.019
adult locomotory behavior GO:0008344 1 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.018
positive regulation of immune system process GO:0002684 283 0.018
oocyte differentiation GO:0009994 2 0.018
zygotic specification of dorsal ventral axis GO:0007352 2 0.018
activin receptor signaling pathway GO:0032924 24 0.018
mitochondrion organization GO:0007005 156 0.018
positive regulation of cellular protein catabolic process GO:1903364 37 0.018
regulation of ion transmembrane transporter activity GO:0032412 72 0.018
negative regulation of kinase activity GO:0033673 106 0.018
Human
regulation of proteasomal protein catabolic process GO:0061136 87 0.018
regulation of gtp catabolic process GO:0033124 180 0.018
purine containing compound catabolic process GO:0072523 411 0.018
spermatid development GO:0007286 4 0.018
negative regulation of transport GO:0051051 176 0.018
negative regulation of smad protein complex assembly GO:0010991 4 0.018
positive regulation of mapk cascade GO:0043410 190 0.018
carboxylic acid biosynthetic process GO:0046394 97 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
lipid metabolic process GO:0006629 381 0.018
inorganic ion transmembrane transport GO:0098660 231 0.018
actin filament bundle organization GO:0061572 54 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
regulation of wnt signaling pathway GO:0030111 123 0.018
zymogen activation GO:0031638 70 0.018
striated muscle tissue development GO:0014706 59 0.018
i kappab kinase nf kappab signaling GO:0007249 166 0.018
photoreceptor cell differentiation GO:0046530 2 0.018
negative regulation of muscle organ development GO:0048635 12 0.018
Human
sodium ion transport GO:0006814 61 0.018
regulation of cellular response to growth factor stimulus GO:0090287 76 0.018
regulation of transcription during mitosis GO:0045896 2 0.018
spermatid differentiation GO:0048515 4 0.017
peripheral nervous system development GO:0007422 2 0.017
regulation of nucleoside metabolic process GO:0009118 209 0.017
lipid biosynthetic process GO:0008610 177 0.017
compound eye development GO:0048749 1 0.017
dna templated transcription initiation GO:0006352 35 0.017
single organism membrane organization GO:0044802 268 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.017
regulation of protein localization to nucleus GO:1900180 85 0.017
endosomal transport GO:0016197 129 0.017
embryonic heart tube morphogenesis GO:0003143 8 0.017
peptidyl serine phosphorylation GO:0018105 101 0.017
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.017
positive regulation of neurogenesis GO:0050769 49 0.017
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.017
aorta development GO:0035904 2 0.017
skin development GO:0043588 76 0.017
positive regulation of developmental growth GO:0048639 16 0.017
atrioventricular valve morphogenesis GO:0003181 2 0.017
positive regulation of cell death GO:0010942 263 0.017
positive regulation of cell adhesion GO:0045785 84 0.017
motor neuron axon guidance GO:0008045 2 0.017
nuclear import GO:0051170 106 0.017
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.016
heart development GO:0007507 95 0.016
Human Mouse
positive regulation of meiotic cell cycle GO:0051446 2 0.016
specification of organ identity GO:0010092 3 0.016
negative regulation of cell cycle phase transition GO:1901988 89 0.016
protein import GO:0017038 130 0.016
positive regulation of peptidase activity GO:0010952 88 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
wound healing GO:0042060 115 0.016
endocytosis GO:0006897 159 0.016
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.016
positive regulation of protein complex assembly GO:0031334 86 0.016
regulation of metal ion transport GO:0010959 120 0.016
regulation of transmembrane transport GO:0034762 139 0.016
positive regulation of kinase activity GO:0033674 204 0.016
regulation of vesicle mediated transport GO:0060627 130 0.016
negative regulation of protein kinase activity GO:0006469 98 0.016
Human
negative regulation of multicellular organismal process GO:0051241 317 0.016
Human
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 1 0.016
blood coagulation GO:0007596 76 0.016
innate immune response GO:0045087 178 0.016
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.016
positive regulation of cell growth GO:0030307 48 0.016
organ induction GO:0001759 4 0.016
response to alcohol GO:0097305 64 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.016
cation transmembrane transport GO:0098655 238 0.016
organic acid biosynthetic process GO:0016053 97 0.016
lymphocyte activation GO:0046649 133 0.016
cell proliferation involved in heart valve development GO:2000793 1 0.016
regulation of transporter activity GO:0032409 82 0.016

MKL2 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.053
disease of cellular proliferation DOID:14566 174 0.053
organ system cancer DOID:0050686 164 0.037
central nervous system disease DOID:331 186 0.032
nervous system disease DOID:863 431 0.032
musculoskeletal system disease DOID:17 223 0.030
disease of metabolism DOID:0014667 295 0.026
cardiovascular system disease DOID:1287 106 0.025
sensory system disease DOID:0050155 203 0.019
heart disease DOID:114 68 0.018
inherited metabolic disorder DOID:655 242 0.017