Homo sapiens

63 known processes

MMP14

matrix metallopeptidase 14 (membrane-inserted)

(Aliases: MMP-X1,MTMMP1,MT1-MMP)

MMP14 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cell migration GO:0030334 289 0.996
enzyme linked receptor protein signaling pathway GO:0007167 303 0.985
regulation of cellular amino acid metabolic process GO:0006521 6 0.981
cellular response to hepatocyte growth factor stimulus GO:0035729 6 0.974
embryonic morphogenesis GO:0048598 85 0.973
ossification GO:0001503 121 0.967
Mouse Rat
regulation of cellular component movement GO:0051270 334 0.959
skeletal system development GO:0001501 79 0.944
Zebrafish Mouse
organ morphogenesis GO:0009887 147 0.943
Zebrafish Mouse
regulation of cell motility GO:2000145 299 0.926
cellular response to growth factor stimulus GO:0071363 197 0.924
regulation of locomotion GO:0040012 329 0.910
positive regulation of cell proliferation GO:0008284 301 0.897
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.876
positive regulation of keratinocyte migration GO:0051549 4 0.867
connective tissue development GO:0061448 39 0.866
Zebrafish
peptidyl tyrosine phosphorylation GO:0018108 170 0.848
positive regulation of locomotion GO:0040017 186 0.848
cellular ketone metabolic process GO:0042180 80 0.845
negative regulation of multicellular organismal process GO:0051241 317 0.845
regulation of neuron differentiation GO:0045664 70 0.840
regulation of cellular response to growth factor stimulus GO:0090287 76 0.835
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.809
endoderm formation GO:0001706 33 0.804
cellular amine metabolic process GO:0044106 41 0.767
positive regulation of protein phosphorylation GO:0001934 313 0.761
response to growth factor GO:0070848 205 0.761
protein processing GO:0016485 226 0.761
Mouse
hepatocyte growth factor receptor signaling pathway GO:0048012 8 0.741
actin filament based process GO:0030029 224 0.728
cell development GO:0048468 328 0.716
Zebrafish
positive regulation of cell motility GO:2000147 177 0.716
single organism cell adhesion GO:0098602 179 0.691
osteoblast differentiation GO:0001649 92 0.686
ameboidal type cell migration GO:0001667 135 0.679
Zebrafish
cellular response to endogenous stimulus GO:0071495 336 0.674
response to transforming growth factor beta GO:0071559 94 0.672
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.667
negative regulation of peptidase activity GO:0010466 91 0.663
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.663
regulation of cellular ketone metabolic process GO:0010565 50 0.662
regulation of cellular amine metabolic process GO:0033238 11 0.656
tissue morphogenesis GO:0048729 96 0.654
Zebrafish Mouse
cartilage development GO:0051216 31 0.653
Zebrafish
generation of neurons GO:0048699 152 0.645
Zebrafish
negative regulation of cellular protein metabolic process GO:0032269 353 0.633
positive regulation of cellular amine metabolic process GO:0033240 7 0.628
regulation of cell adhesion GO:0030155 166 0.617
Rat
negative regulation of protein metabolic process GO:0051248 391 0.595
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.594
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.586
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.580
endodermal cell differentiation GO:0035987 31 0.578
positive regulation of cell migration GO:0030335 172 0.576
taxis GO:0042330 157 0.550
Zebrafish
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.545
regulation of keratinocyte migration GO:0051547 4 0.517
neurogenesis GO:0022008 169 0.513
Zebrafish Rat
regulation of mapk cascade GO:0043408 262 0.508
negative regulation of platelet derived growth factor receptor signaling pathway GO:0010642 4 0.504
amine metabolic process GO:0009308 44 0.499
nervous system development GO:0007399 293 0.498
Zebrafish Rat
regulation of cell projection organization GO:0031344 107 0.495
negative regulation of developmental process GO:0051093 247 0.491
cyclic nucleotide metabolic process GO:0009187 82 0.480
integrin mediated signaling pathway GO:0007229 32 0.476
epithelial cell migration GO:0010631 119 0.469
regulation of cell development GO:0060284 161 0.467
embryonic camera type eye development GO:0031076 2 0.463
negative regulation of catalytic activity GO:0043086 335 0.461
mapk cascade GO:0000165 288 0.456
ephrin receptor signaling pathway GO:0048013 15 0.456
negative regulation of cell development GO:0010721 48 0.451
neuron development GO:0048666 113 0.440
Zebrafish
regulation of ossification GO:0030278 58 0.409
embryonic organ development GO:0048568 36 0.398
Zebrafish Mouse
negative regulation of locomotion GO:0040013 118 0.396
collagen catabolic process GO:0030574 10 0.394
Mouse
negative regulation of cellular component movement GO:0051271 106 0.391
negative regulation of hydrogen peroxide metabolic process GO:0010727 3 0.389
positive regulation of organelle organization GO:0010638 195 0.382
regulation of cell differentiation GO:0045595 393 0.381
cell projection organization GO:0030030 252 0.378
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 144 0.368
Zebrafish
cellular component morphogenesis GO:0032989 314 0.364
Zebrafish
extracellular matrix organization GO:0030198 41 0.356
negative regulation of transport GO:0051051 176 0.354
protein catabolic process GO:0030163 325 0.352
regulation of endopeptidase activity GO:0052548 170 0.351
negative regulation of trophoblast cell migration GO:1901164 3 0.340
negative regulation of cell motility GO:2000146 104 0.335
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.330
negative regulation of proteolysis GO:0045861 132 0.328
regulation of ion transport GO:0043269 189 0.321
positive regulation of protein kinase activity GO:0045860 190 0.317
neuron projection development GO:0031175 106 0.315
Zebrafish
regulation of cytoskeleton organization GO:0051493 177 0.313
cell morphogenesis GO:0000902 296 0.297
Zebrafish
cell adhesion GO:0007155 325 0.296
Rat
cell substrate adhesion GO:0031589 132 0.295
Rat
signal transduction by phosphorylation GO:0023014 297 0.288
regulation of cellular component biogenesis GO:0044087 281 0.285
Rat
positive regulation of cellular component movement GO:0051272 181 0.282
positive regulation of cytoskeleton organization GO:0051495 83 0.281
positive regulation of immune system process GO:0002684 283 0.267
cell chemotaxis GO:0060326 112 0.259
protein maturation GO:0051604 233 0.257
Mouse
single organismal cell cell adhesion GO:0016337 148 0.252
cation transport GO:0006812 331 0.249
epithelium migration GO:0090132 119 0.242
muscle cell migration GO:0014812 19 0.234
skeletal system morphogenesis GO:0048705 24 0.232
Zebrafish Mouse
negative regulation of protein maturation GO:1903318 142 0.232
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.232
Zebrafish
negative regulation of cell differentiation GO:0045596 171 0.231
cell growth GO:0016049 160 0.230
regulation of peptidase activity GO:0052547 180 0.228
Rat
epithelium development GO:0060429 227 0.228
Zebrafish Mouse
embryonic viscerocranium morphogenesis GO:0048703 1 0.228
regulation of protein localization GO:0032880 296 0.227
cellular response to organic cyclic compound GO:0071407 127 0.227
cellular amino acid metabolic process GO:0006520 116 0.227
regulation of actin cytoskeleton organization GO:0032956 116 0.223
regulation of protein catabolic process GO:0042176 155 0.223
negative regulation of hydrolase activity GO:0051346 182 0.218
anatomical structure formation involved in morphogenesis GO:0048646 284 0.217
negative regulation of endopeptidase activity GO:0010951 84 0.215
negative regulation of transferase activity GO:0051348 124 0.215
regulation of metalloenzyme activity GO:0048552 3 0.214
protein modification by small protein conjugation GO:0032446 342 0.214
appendage morphogenesis GO:0035107 16 0.214
establishment of planar polarity GO:0001736 3 0.211
positive regulation of cellular component organization GO:0051130 376 0.210
regulation of nervous system development GO:0051960 88 0.208
negative regulation of protein modification process GO:0031400 200 0.207
negative regulation of cell proliferation GO:0008285 228 0.206
response to cytokine GO:0034097 232 0.206
neuron projection morphogenesis GO:0048812 50 0.203
Zebrafish
positive regulation of cellular component biogenesis GO:0044089 158 0.200
sensory organ morphogenesis GO:0090596 21 0.200
Zebrafish
formation of primary germ layer GO:0001704 42 0.195
regulation of anatomical structure morphogenesis GO:0022603 286 0.193
camp metabolic process GO:0046058 61 0.190
biological adhesion GO:0022610 331 0.188
Rat
cellular response to acid chemical GO:0071229 44 0.188
regulation of neuron projection development GO:0010975 57 0.183
regulation of kinase activity GO:0043549 314 0.183
immune response activating signal transduction GO:0002757 90 0.182
cell part morphogenesis GO:0032990 137 0.180
Zebrafish
positive regulation of protein oligomerization GO:0032461 17 0.173
wnt signaling pathway GO:0016055 156 0.172
positive regulation of phosphorylation GO:0042327 394 0.170
compound eye development GO:0048749 1 0.167
single organism cellular localization GO:1902580 332 0.166
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.164
regulation of epithelial cell migration GO:0010632 93 0.164
actin cytoskeleton organization GO:0030036 207 0.160
canonical wnt signaling pathway GO:0060070 116 0.160
regulation of protein complex assembly GO:0043254 147 0.159
regulation of cell growth GO:0001558 135 0.159
vesicle mediated transport GO:0016192 371 0.158
regulation of protein processing GO:0070613 150 0.154
multi organism cellular process GO:0044764 156 0.153
regulation of transferase activity GO:0051338 355 0.150
positive regulation of vascular endothelial growth factor signaling pathway GO:1900748 3 0.149
mesenchyme development GO:0060485 59 0.148
positive regulation of protein transport GO:0051222 135 0.147
positive regulation of fibrinolysis GO:0051919 4 0.146
regulation of protein maturation GO:1903317 150 0.146
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 6 0.146
negative regulation of protein processing GO:0010955 142 0.145
negative regulation of membrane protein ectodomain proteolysis GO:0051045 4 0.143
negative regulation of cellular catabolic process GO:0031330 83 0.138
tube development GO:0035295 125 0.137
neuron differentiation GO:0030182 138 0.136
Zebrafish
negative regulation of protein catabolic process GO:0042177 59 0.135
positive regulation of immune response GO:0050778 159 0.135
embryonic organ morphogenesis GO:0048562 24 0.133
Zebrafish Mouse
morphogenesis of an epithelium GO:0002009 60 0.132
Zebrafish Mouse
cellular response to lipid GO:0071396 127 0.132
embryonic eye morphogenesis GO:0048048 2 0.130
regulation of neurogenesis GO:0050767 82 0.129
positive regulation of protein complex assembly GO:0031334 86 0.128
positive regulation of cell differentiation GO:0045597 211 0.128
regulation of nucleotide metabolic process GO:0006140 269 0.126
negative regulation of neurogenesis GO:0050768 26 0.126
regeneration GO:0031099 4 0.125
amide biosynthetic process GO:0043604 15 0.124
cellular macromolecule catabolic process GO:0044265 380 0.124
viral life cycle GO:0019058 132 0.122
female gamete generation GO:0007292 2 0.122
regulation of growth GO:0040008 165 0.122
negative regulation of multi organism process GO:0043901 92 0.121
blood vessel morphogenesis GO:0048514 162 0.121
Rat
neural crest cell development GO:0014032 3 0.119
ion transmembrane transport GO:0034220 338 0.118
response to oxygen containing compound GO:1901700 369 0.116
tissue migration GO:0090130 119 0.113
regulation of osteoblast differentiation GO:0045667 38 0.113
cranial nerve development GO:0021545 4 0.112
regulation of leukocyte migration GO:0002685 63 0.111
nuclear transport GO:0051169 179 0.109
secretion GO:0046903 254 0.108
negative regulation of cell migration GO:0030336 102 0.107
endothelial cell migration GO:0043542 86 0.107
actin filament organization GO:0007015 128 0.106
establishment of tissue polarity GO:0007164 3 0.105
regulation of protein ubiquitination GO:0031396 95 0.105
platelet derived growth factor receptor signaling pathway GO:0048008 14 0.103
response to organonitrogen compound GO:0010243 156 0.103
regulation of receptor catabolic process GO:2000644 2 0.102
positive regulation of developmental process GO:0051094 314 0.101
protein oligomerization GO:0051259 173 0.100
response to wounding GO:0009611 168 0.097
circulatory system development GO:0072359 262 0.096
Rat
regulation of actin filament based process GO:0032970 141 0.095
embryonic camera type eye morphogenesis GO:0048596 2 0.095
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.095
negative regulation of axonogenesis GO:0050771 4 0.094
signal peptide processing GO:0006465 3 0.093
negative regulation of cellular component organization GO:0051129 235 0.093
Rat
positive regulation of neuron projection development GO:0010976 34 0.093
neurotrophin trk receptor signaling pathway GO:0048011 4 0.092
cell projection morphogenesis GO:0048858 129 0.092
Zebrafish
negative regulation of catabolic process GO:0009895 104 0.091
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.091
peptidyl tyrosine modification GO:0018212 170 0.091
reproductive process GO:0022414 106 0.091
Rat
regulation of camp metabolic process GO:0030814 52 0.091
cellular response to interleukin 1 GO:0071347 35 0.091
response to tumor necrosis factor GO:0034612 76 0.090
transmembrane transport GO:0055085 399 0.089
embryo development GO:0009790 123 0.088
wound healing GO:0042060 115 0.087
protein ubiquitination GO:0016567 314 0.087
appendage development GO:0048736 23 0.086
oogenesis GO:0048477 2 0.086
regulation of transmembrane transport GO:0034762 139 0.085
hematopoietic or lymphoid organ development GO:0048534 186 0.085
leukocyte migration GO:0050900 107 0.084
motor neuron axon guidance GO:0008045 2 0.084
cellular response to cytokine stimulus GO:0071345 181 0.083
erk1 and erk2 cascade GO:0070371 104 0.082
cytokine production GO:0001816 247 0.081
regulation of receptor mediated endocytosis GO:0048259 32 0.081
digestive tract morphogenesis GO:0048546 56 0.080
negative regulation of nervous system development GO:0051961 28 0.079
regulation of cartilage development GO:0061035 12 0.078
regulation of cytokine production GO:0001817 232 0.078
regulation of cell cell adhesion GO:0022407 57 0.078
positive regulation of epithelial cell migration GO:0010634 55 0.078
insulin processing GO:0030070 1 0.077
cell junction assembly GO:0034329 67 0.077
Rat
endocytosis GO:0006897 159 0.077
neurotrophin production GO:0032898 2 0.077
ribonucleoside catabolic process GO:0042454 406 0.077
negative regulation of transforming growth factor beta1 production GO:0032911 2 0.077
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.075
cellular response to nitrogen compound GO:1901699 144 0.074
cellular response to hormone stimulus GO:0032870 125 0.074
cellular protein catabolic process GO:0044257 261 0.074
growth GO:0040007 202 0.073
sensory organ development GO:0007423 52 0.073
Zebrafish
regulation of smooth muscle cell migration GO:0014910 15 0.070
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.070
regulation of cellular response to stress GO:0080135 244 0.070
negative regulation of phosphate metabolic process GO:0045936 267 0.070
membrane organization GO:0061024 292 0.070
angiogenesis GO:0001525 147 0.070
Rat
cellular response to oxygen containing compound GO:1901701 276 0.069
regulation of nucleocytoplasmic transport GO:0046822 98 0.069
anterior posterior axis specification GO:0009948 2 0.069
Zebrafish
positive regulation of neurogenesis GO:0050769 49 0.068
positive regulation of mapk cascade GO:0043410 190 0.067
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.067
regulation of purine nucleotide metabolic process GO:1900542 264 0.067
purine nucleotide catabolic process GO:0006195 405 0.066
ribonucleoside triphosphate metabolic process GO:0009199 412 0.064
tissue regeneration GO:0042246 3 0.064
tube morphogenesis GO:0035239 95 0.064
transforming growth factor beta1 production GO:0032905 3 0.064
regulation of defense response GO:0031347 154 0.064
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.063
regulation of cytoplasmic transport GO:1903649 149 0.063
axon development GO:0061564 34 0.061
Zebrafish
posttranscriptional regulation of gene expression GO:0010608 213 0.061
multicellular organismal macromolecule metabolic process GO:0044259 29 0.061
Mouse
cell activation GO:0001775 213 0.061
protein targeting GO:0006605 187 0.060
positive regulation of axon extension GO:0045773 4 0.060
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.059
cartilage morphogenesis GO:0060536 1 0.059
regulation of hormone levels GO:0010817 125 0.059
regulation of intracellular transport GO:0032386 195 0.059
negative regulation of cell adhesion GO:0007162 64 0.058
Rat
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.058
cytokine mediated signaling pathway GO:0019221 109 0.058
negative regulation of transforming growth factor beta production GO:0071635 4 0.058
smooth muscle cell migration GO:0014909 18 0.058
nerve growth factor production GO:0032902 2 0.058
regulation of inflammatory response GO:0050727 46 0.057
intracellular protein transport GO:0006886 270 0.057
reactive oxygen species metabolic process GO:0072593 75 0.057
positive regulation of actin filament bundle assembly GO:0032233 25 0.057
endoderm development GO:0007492 33 0.057
blastoderm segmentation GO:0007350 2 0.057
cell adhesion mediated by integrin GO:0033627 27 0.056
response to hypoxia GO:0001666 96 0.056
Zebrafish Rat
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.056
organonitrogen compound biosynthetic process GO:1901566 200 0.055
gastrulation GO:0007369 51 0.055
regulation of protein binding GO:0043393 66 0.054
membrane protein ectodomain proteolysis GO:0006509 33 0.054
multicellular organismal metabolic process GO:0044236 34 0.054
Mouse
morphogenesis of embryonic epithelium GO:0016331 4 0.053
establishment of protein localization to membrane GO:0090150 121 0.053
segmentation GO:0035282 4 0.053
regulation of jnk cascade GO:0046328 73 0.053
positive regulation of intracellular protein transport GO:0090316 76 0.052
establishment of protein localization to plasma membrane GO:0090002 68 0.052
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.052
regulation of stress fiber assembly GO:0051492 32 0.052
receptor catabolic process GO:0032801 11 0.051
vasculature development GO:0001944 181 0.051
Rat
regulation of blood coagulation GO:0030193 42 0.051
regulation of transforming growth factor beta production GO:0071634 13 0.051
replacement ossification GO:0036075 1 0.051
Mouse
carbohydrate derivative biosynthetic process GO:1901137 207 0.051
interspecies interaction between organisms GO:0044419 156 0.051
proteoglycan catabolic process GO:0030167 3 0.050
chordate embryonic development GO:0043009 34 0.050
Zebrafish Mouse
nucleoside catabolic process GO:0009164 408 0.050
regulation of epithelial cell proliferation GO:0050678 113 0.050
negative regulation of protein phosphorylation GO:0001933 140 0.049
hormone metabolic process GO:0042445 61 0.049
regulation of cellular component size GO:0032535 82 0.049
cardiovascular system development GO:0072358 262 0.048
Rat
positive regulation of hydrolase activity GO:0051345 331 0.048
Rat
regulation of establishment of protein localization GO:0070201 242 0.048
cranial nerve morphogenesis GO:0021602 1 0.047
response to mechanical stimulus GO:0009612 51 0.047
Rat
response to hormone GO:0009725 175 0.046
Rat
response to acid chemical GO:0001101 66 0.046
luteolysis GO:0001554 3 0.046
regulation of canonical wnt signaling pathway GO:0060828 88 0.045
neural tube formation GO:0001841 3 0.045
response to organic cyclic compound GO:0014070 204 0.045
Rat
negative regulation of ion transport GO:0043271 39 0.045
positive regulation of lymphocyte activation GO:0051251 73 0.045
embryonic epithelial tube formation GO:0001838 4 0.045
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.045
negative regulation of apoptotic process GO:0043066 316 0.044
regulation of proteolysis GO:0030162 293 0.044
Rat
protein localization to nucleus GO:0034504 136 0.043
embryonic skeletal system morphogenesis GO:0048704 9 0.043
Zebrafish Mouse
regulation of hepatocyte growth factor receptor signaling pathway GO:1902202 4 0.043
determination of adult lifespan GO:0008340 2 0.043
limb development GO:0060173 23 0.042
negative regulation of neuron projection development GO:0010977 15 0.042
single organism carbohydrate metabolic process GO:0044723 193 0.042
kinin cascade GO:0002254 1 0.042
morphogenesis of a polarized epithelium GO:0001738 3 0.041
collagen fibril organization GO:0030199 10 0.041
positive regulation of epithelial cell proliferation GO:0050679 65 0.041
single organism nuclear import GO:1902593 104 0.041
regulation of protein import into nucleus GO:0042306 78 0.041
oocyte differentiation GO:0009994 2 0.041
positive regulation of fibroblast migration GO:0010763 3 0.041
positive regulation of proteolysis GO:0045862 142 0.040
Rat
circulatory system process GO:0003013 113 0.040
protein localization to membrane GO:0072657 160 0.040
multicellular organismal aging GO:0010259 3 0.040
positive regulation of leukocyte chemotaxis GO:0002690 38 0.039
response to oxygen levels GO:0070482 100 0.039
Zebrafish Rat
viral process GO:0016032 146 0.039
negative regulation of anoikis GO:2000811 15 0.039
angiogenesis involved in wound healing GO:0060055 4 0.039
skin development GO:0043588 76 0.039
regulation of binding GO:0051098 111 0.039
vascular endothelial growth factor receptor signaling pathway GO:0048010 19 0.039
myeloid cell differentiation GO:0030099 117 0.038
lymphocyte activation GO:0046649 133 0.038
regulation of vesicle mediated transport GO:0060627 130 0.038
response to estrogen GO:0043627 47 0.038
Rat
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.038
semaphorin plexin signaling pathway GO:0071526 4 0.038
keratinocyte migration GO:0051546 6 0.037
tripartite regional subdivision GO:0007351 2 0.037
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.037
response to interleukin 1 GO:0070555 47 0.037
regulation of protein localization to nucleus GO:1900180 85 0.037
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.037
hemopoiesis GO:0030097 180 0.036
rho protein signal transduction GO:0007266 26 0.036
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.036
negative regulation of response to cytokine stimulus GO:0060761 25 0.036
regulation of cell morphogenesis GO:0022604 153 0.035
response to increased oxygen levels GO:0036296 4 0.035
jak stat cascade GO:0007259 46 0.035
anterior posterior axis specification embryo GO:0008595 2 0.035
regulation of cell matrix adhesion GO:0001952 42 0.035
Rat
glial cell migration GO:0008347 4 0.035
Rat
response to hepatocyte growth factor GO:0035728 6 0.035
stress fiber assembly GO:0043149 40 0.034
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.034
dendritic spine morphogenesis GO:0060997 3 0.034
bone morphogenesis GO:0060349 10 0.034
Mouse
regulation of immune response GO:0050776 201 0.033
cytoplasmic transport GO:0016482 379 0.033
bone trabecula formation GO:0060346 1 0.033
negative regulation of cell projection organization GO:0031345 22 0.033
multi organism reproductive process GO:0044703 54 0.033
response to decreased oxygen levels GO:0036293 96 0.033
Zebrafish Rat
positive regulation of transport GO:0051050 336 0.033
regulation of cell adhesion mediated by integrin GO:0033628 22 0.033
endochondral bone morphogenesis GO:0060350 3 0.032
Mouse
stem cell development GO:0048864 69 0.032
regulation of wnt signaling pathway GO:0030111 123 0.032
organic hydroxy compound transport GO:0015850 63 0.032
plasma membrane organization GO:0007009 115 0.032
renal system development GO:0072001 63 0.032
cellular component disassembly GO:0022411 92 0.032
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 18 0.031
carbohydrate metabolic process GO:0005975 207 0.031
single organism reproductive process GO:0044702 98 0.031
Rat
response to inorganic substance GO:0010035 127 0.031
immune response GO:0006955 307 0.031
regulation of peptidyl serine phosphorylation GO:0033135 50 0.031
bone development GO:0060348 26 0.031
Mouse
regulation of angiogenesis GO:0045765 92 0.030
regulation of protein targeting GO:1903533 91 0.030
regulation of reproductive process GO:2000241 15 0.030
regulation of erk1 and erk2 cascade GO:0070372 99 0.030
actin polymerization or depolymerization GO:0008154 56 0.030
regulation of vasodilation GO:0042312 4 0.030
regulation of secretion by cell GO:1903530 177 0.030
positive regulation of cell development GO:0010720 92 0.030
oocyte development GO:0048599 1 0.030
cellular response to organonitrogen compound GO:0071417 124 0.029
female pregnancy GO:0007565 17 0.029
head development GO:0060322 108 0.029
activation of immune response GO:0002253 114 0.029
actin filament bundle assembly GO:0051017 54 0.029
regulation of actin filament bundle assembly GO:0032231 36 0.029
cellular response to tumor necrosis factor GO:0071356 63 0.029
negative regulation of cell death GO:0060548 345 0.029
immune response regulating signaling pathway GO:0002764 97 0.029
trabecula morphogenesis GO:0061383 2 0.028
negative regulation of ligase activity GO:0051352 8 0.028
salivary gland morphogenesis GO:0007435 4 0.028
nucleocytoplasmic transport GO:0006913 176 0.028
regulation of ubiquitin protein transferase activity GO:0051438 28 0.028
negative regulation of protein kinase activity GO:0006469 98 0.028
sensory perception of pain GO:0019233 4 0.028
membrane protein proteolysis GO:0033619 38 0.027
regulation of ion transmembrane transport GO:0034765 132 0.027
regulation of cytokine mediated signaling pathway GO:0001959 41 0.027
nucleoside triphosphate catabolic process GO:0009143 394 0.027
positive regulation of cell projection organization GO:0031346 64 0.027
purine nucleoside catabolic process GO:0006152 398 0.027
positive regulation of leukocyte migration GO:0002687 46 0.027
transforming growth factor beta production GO:0071604 14 0.027
peptide metabolic process GO:0006518 51 0.027
regulation of secretion GO:0051046 194 0.026
bone mineralization GO:0030282 34 0.026
regulation of multi organism process GO:0043900 157 0.026
positive regulation of nervous system development GO:0051962 54 0.026
purine ribonucleoside catabolic process GO:0046130 398 0.026
regulation of response to external stimulus GO:0032101 222 0.026
positive regulation of odontogenesis GO:0042482 3 0.026
regulation of protein oligomerization GO:0032459 26 0.026
post embryonic development GO:0009791 2 0.026
negative regulation of growth GO:0045926 97 0.025
single organism membrane organization GO:0044802 268 0.025
negative regulation of kinase activity GO:0033673 106 0.025
central nervous system neuron axonogenesis GO:0021955 3 0.025
regulation of apoptotic signaling pathway GO:2001233 175 0.025
apoptotic signaling pathway GO:0097190 268 0.025
positive regulation of jak stat cascade GO:0046427 35 0.025
substrate adhesion dependent cell spreading GO:0034446 41 0.025
negative regulation of metalloenzyme activity GO:0048553 1 0.025
response to drug GO:0042493 81 0.025
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 9 0.024

MMP14 disease predictions

Disease DO term ID Size Probability Func Analog Org
osteochondrodysplasia DOID:2256 35 0.133
bone development disease DOID:0080006 55 0.133
bone disease DOID:0080001 88 0.133
musculoskeletal system disease DOID:17 223 0.133
connective tissue disease DOID:65 109 0.133
osteogenesis imperfecta DOID:12347 13 0.117
disease of metabolism DOID:0014667 295 0.052
inherited metabolic disorder DOID:655 242 0.052
acquired metabolic disease DOID:0060158 58 0.033
central nervous system disease DOID:331 186 0.031
nervous system disease DOID:863 431 0.031
cancer DOID:162 167 0.029
disease of cellular proliferation DOID:14566 174 0.029